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https://www.readbyqxmd.com/read/28226678/hip-segmentation-from-mri-volumes-in-infants-for-ddh-diagnosis-and-treatment-planning
#1
Abhilash Rakkunedeth Hareendranathan, Dornoosh Zonoobi, Myles Mabee, Chad Diederichs, Kumaradevan Punithakumar, Michelle Noga, Jacob L Jaremko, Abhilash Rakkunedeth Hareendranathan, Dornoosh Zonoobi, Myles Mabee, Chad Diederichs, Kumaradevan Punithakumar, Michelle Noga, Jacob L Jaremko, Jacob L Jaremko, Myles Mabee, Dornoosh Zonoobi, Michelle Noga, Chad Diederichs, Kumaradevan Punithakumar, Abhilash Rakkunedeth Hareendranathan
Diagnosis and surgical management of Developmental Dysplasia of the Hip (DDH) relies on physical examination and 2D ultrasound scanning. Magnetic Resonance Imaging (MRI) can be used to complement existing techniques and could be advantageous in treatment planning due to its larger field of view. In this paper we propose a semi-automatic method to segment surface models of the acetabulum from MRI images. The method incorporates clinical knowledge in the form of intensity priors which are integrated into a Random Walker (RW) formulation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28222640/dynamic-long-leg-casting-fixation-for-treating-12-to-18-month-old-infants-with-developmental-dysplasia-of-the-hip
#2
Zhencun Cai, Lianyong Li, Lijun Zhang, Shijun Ji, Qun Zhao
Objective To evaluate the effect of dynamic long leg casting in paediatric patients with developmental dysplasia of hip (DDH) diagnosed at 12-18 months. Methods The adductor tenotomy, closed reduction, and dynamic long leg casting method was adopted to treat paediatric patients with DDH. The hips were divided into four groups according to the Tonnis radiographic dislocation classification. Groups were also classified according to the baseline acetabular index (AI): 30°-35°, 36°-40°, and > 40°. The outcomes of the reductions were evaluated according to McKay's hip function criteria and Severin's radiological criteria...
February 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28213129/cyclic-compressive-stress-induced-scinderin-regulates-progress-of-developmental-dysplasia-of-the-hip
#3
Cheng-Long Wang, Hui Wang, Fei Xiao, Chuan-Dong Wang, Guo-Li Hu, Jun-Feng Zhu, Chao Shen, Bin Zuo, Yi-Min Cui, De Li, Yuan-Gao, Xiao-Ling Zhang, Xiao-Dong Chen
Developmental dysplasia of the hip (DDH) is a common musculoskeletal disorder characterized by a mismatch between acetabulum and femoral head. Mechanical force plays an important role during the occurrence and development of abnormities in acetabulum and femoral head. In this study, we established a mechanical force model named cyclic compressive stress (Ccs). To analyze the effect of Ccs on DDH, we detected special genes in chondrocytes and osteoblasts. Results showed that Ccs downregulated chondrogenesis of ADTC5 in a concentration-dependent manner...
February 14, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28185391/severe-cartilage-degeneration-in-patients-with-developmental-dysplasia-of-the-hip
#4
Wei-Jia Feng, Hui Wang, Chao Shen, Jun-Feng Zhu, Xiao-Dong Chen
Developmental dysplasia of the hip (DDH) is a developmental disorder that has long-term chronic pain and limited hip joint mobility as major pathological characteristics. This study aims to access the association between the development of DDH and cartilage metabolic disorders. Cartilage tissue samples were acquired from patients with DDH, osteoarthritis (OA) and femoral neck fracture. The proteoglycan level was evaluated by safranin O-fast green, toluidine blue and hematoxylin-eosin (HE) staining. The levels of collagen-II (Col-II), collagen-X (Col-X) and metal matrix proteinase-13 (MMP-13) were evaluated by immunohistochemistry (IHC) and Western blotting analysis...
February 10, 2017: IUBMB Life
https://www.readbyqxmd.com/read/28176570/parents-know-best-in-infant-hip-screening-programme
#5
Angie Lee
The importance of early identification of developmental dysplasia of the hip (DDH) is well documented, and there has been a national screening programme since the early 1960s. Until 2008, infants were checked at birth, then at six weeks and eight months; the check at eight months has since been discontinued.
February 8, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28151382/pyrobaculum-igneiluti-sp-nov-a-novel-anaerobic-hyperthermophilic-archaeon-that-reduces-thiosulfate-and-ferric-iron
#6
Jerry Y Lee, Brenda Iglesias, Caleb E Chu, Daniel J P Lawrence, Edward J Crane Iii
A novel anaerobic, hyperthermophilic archaeon was isolated from a mud volcano in the Salton Sea geothermal system in Southern California, USA. The isolate, named strain 521T, grew optimally at 90°C, pH 5.5-7.3, and 0-2.0% w/v NaCl, with a generation time of 10 hours under optimal conditions. Cells were rod-shaped and nonmotile, ranging from 2-7 μm in length. Strain 521T grew only in the presence of thiosulfate and/or Fe(III) (ferrihydrite) as terminal electron acceptors in strictly anaerobic conditions, and preferred protein-rich compounds as energy sources, although the isolate was capable of chemolithoautotrophic growth...
February 2, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28150577/whole-genome-sequences-reveal-vibrio-hemicentroti-kim-et-al-2013-as-a-later-heterotypic-synonym-of-vibrio-splendidus-beijerinck-1900-baumann-et-al-1981
#7
Teresa Lucena, M Carmen Macián, David R Arahal, Lidia Rodrigo-Torres, María J Pujalte
The synonymy between Vibrio hemicentroti Kim et al. 2013 and Vibrio splendidus (Beijerinck 1900) Baumann et al. 1981 was suggested after a recent multilocus sequence analysis (MLSA) of the Splendidus clade which included both type strains (Pérez-Cataluña et al., 2016). In order to clarify their status, we have determined genomic indexes from whole genome sequences of strains V. hemicentroti CECT 8714T and V. splendidus NCCB 53037T. ANI indexes of 96.0 to 96.7% and in silico DDH values of 70.2%, as well as similarity levels of selected housekeeping gene sequences support the consideration of V...
February 1, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28150480/adequate-dietary-fiber-supplement-along-with-tone-concept-can-help-avoid-surgery-in-most-patients-with-advanced-hemorrhoids
#8
Pankaj Garg, Pratiksha Singh
BACKGROUND: The root cause of hemorrhoids are three deranged defecation habits (DDH) - (1) increased straining, (2) prolonged defecation-time and, (3) frequent bowel-motions. These DDH are responsible for development of new hemorrhoids, progression of existing hemorrhoids and hemorrhoidal rupture (bleeding). DDH can be corrected by TONE concept. TONE entails specifying exact treatment goals (T-Three minutes at defecation, O-Once a day defecation- frequency, N-No straining during passing motions, E-Enough fiber)...
February 1, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28141499/streptomyces-jeddahensis-sp-nov-an-oleaginous-bacterium-isolated-from-desert-soil
#9
Annika Röttig, Ewelina Atasayar, Jan Philipp Meier-Kolthoff, Cathrin Spröer, Peter Schumann, Jennifer Schauer, Alexander Steinbüchel
A novel strain, G25T, was isolated from desert soil collected near Jeddah in Saudi Arabia. It can accumulate nearly 65% fatty acids of its cell dry weight, grows on a broad range of carbon sources, and tolerates temperatures of up to 50°C. According to its 16S rRNA gene sequence, strain G25T is most closely related to Streptomyces massasporeus DSM 40035T, Streptomyces hawaiiensis DSM 40042T, Streptomyces indiaensis DSM 43803T, Streptomyces luteogriseus DSM 40483T, and Streptomyces purpurascens DSM 40310T. Conventional DNA:DNA hybridization (DDH) values ranged from 18...
January 30, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28116042/high-quality-draft-genome-sequence-of-janthinobacterium-psychrotolerans-sp-nov-isolated-from-a-frozen-freshwater-pond
#10
Xianzhe Gong, Stig Skrivergaard, Benjamin Smed Korsgaard, Lars Schreiber, Ian P G Marshall, Kai Finster, Andreas Schramm
Strain S3-2(T), isolated from sediment of a frozen freshwater pond, shares 99% 16S rRNA gene sequence identity with strains of the genus Janthinobacterium. Strain S3-2(T) is a facultative anaerobe that lacks the ability to produce violacein but shows antibiotic resistance, psychrotolerance, incomplete denitrification, and fermentation. The draft genome of strain S3-2(T) has a size of ~5.8 Mbp and contains 5,297 genes, including 115 RNA genes. Based on the phenotypic properties of the strain, the low in silico DNA-DNA hybridization (DDH) values with related genomes (<35%), and the low whole genome-based average nucleotide identity (ANI) (<86%) with other strains within the genus Janthinobacterium, we propose that strain S3-2(T) is the type strain (= DSM 102223 = LMG 29653) of a new species within this genus...
2017: Standards in Genomic Sciences
https://www.readbyqxmd.com/read/28109208/psychromonas-aquatilis-sp-nov-isolated-from-water-samples-obtained-in-the-chilean-antarctica
#11
Peter Kämpfer, Rute Irgang, Mathías Poblete-Morales, Stefanie P Glaeser, Marcelo Cortez-San Martín, Ruben Avendaño-Herrera
One slightly beige-white pigmented, Gram-staining negative, rod-shaped bacterium, strain M1A1T, was isolated from seawater samples obtained in Fildes Bay, Antarctica (62º12´S, 58º57´W). Phylogenetic analysis based on nearly full-length 16S rRNA gene sequences showed that the isolate shared 98.4 % 16S rRNA gene sequence identity to the type strain of the species Psychromonas arctica, but less than 97 % 16S rRNA gene sequence similarities to all other Psychromonas species. DNA-DNA hybridisation (DDH) with Psychromonas arctica DSM 14288T showed low values (21 %, reciprocal 27 %)...
January 19, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28099350/retrospective-observational-study-comparing-the-international-hip-dysplasia-institute-classification-with-the-tonnis-classification-of-developmental-dysplasia-of-the-hip
#12
Mingyuan Miao, Haiqing Cai, Liwei Hu, Zhigang Wang
The Tonnis radiographic classification of developmental dysplasia of the hip (DDH) has been widely used. The International Hip Dysplasia Institute (IHDI) classification, a new classification system recently developed by the IHDI, is beginning to be applied to evaluate DDH with the absence of an ossification center. This study aimed to validate its reliability in evaluating DDH with an ossification center and compared the 2 classifications in evaluating all DDH hips. In addition, the prediction values of the 2 classifications on clinical management selection were compared...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28075436/gait-kinematic-deviations-in-patients-with-developmental-dysplasia-of-the-hip-treated-with-total-hip-arthroplasty
#13
Yong Nie, Ning Ning, Fuxing Pei, Bin Shen, Zongke Zhou, Zongming Li
Comprehensive gait analysis of patients with Crowe type II and III developmental dysplasia of the hip (DDH) after successful total hip arthroplasty (THA) is lacking in the literature. This study evaluated gait function in joint kinematics after unilateral and bilateral THA in patients with DDH. In addition, the effect of high cup position on gait function was investigated. A total of 16 unilateral and 15 bilateral cementless THA patients due to DDH and 10 healthy participants comprised the study population...
January 11, 2017: Orthopedics
https://www.readbyqxmd.com/read/28066739/hip-instability-a-review-of-hip-dysplasia-and-other-contributing-factors
#14
REVIEW
Matthew J Kraeutler, Tigran Garabekyan, Cecilia Pascual-Garrido, Omer Mei-Dan
BACKGROUND: Hip instability has classically been associated with developmental dysplasia of the hip (DDH) in newborns and children. However, numerous factors may contribute to hip instability in children, adolescents, and adults. PURPOSE: This review aims to concisely present the literature on hip instability in patients of all ages in order to guide health care professionals in the appropriate diagnosis and treatment of the various disorders which may contribute to an unstable hip...
July 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28053253/minimally-invasive-periacetabular-osteotomy-using-a-modified-smith-petersen-approach-technique-and-early-outcomes
#15
O H Khan, A Malviya, P Subramanian, D Agolley, J D Witt
AIMS: Periacetabular osteotomy is an effective way of treating symptomatic hip dysplasia. We describe a new minimally invasive technique using a modification of the Smith-Peterson approach. We performed a prospective, longitudinal cohort study to assess for any compromise in acetabular correction when using this approach, and to see if the procedure would have a higher complication rate than that quoted in the literature for other approaches. We also assessed for any improvement in functional outcome...
January 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28040300/neptuniibacter-pectenicola-sp-nov-and-neptuniibacter-marinus-sp-nov-two-novel-species-isolated-from-a-great-scallop-pecten-maximus-hatchery-in-norway-and-emended-description-of-the-genus-neptuniibacter
#16
Ana L Diéguez, Sabela Balboa, Thorolf Magnesen, Jesús L Romalde
Nine isolates obtained from a great scallop hatchery in Norway were characterized using a polyphasic approach. Strains were Gram-negative, aerobic and motile rods with oxidative metabolism. Phylogenetic analysis based on the sequences of 16S rRNA and rpoB genes showed that these strains formed two different groups associated with members of the genus Neptuniibacter. DNA-DNA hybridization (DDH) and Average Nucleotide Identity (ANI) demonstrated that the isolates constituted two novel species of this genus, which can be phenotypically differentiated from their closest relatives...
December 21, 2016: Systematic and Applied Microbiology
https://www.readbyqxmd.com/read/28032035/seasonal-variation-in-adult-hip-disease-secondary-to-osteoarthritis-and-developmental-dysplasia-of-the-hip
#17
Tatsuya Sueyoshi, Merrill A Ritter, Kenneth E Davis, Randall T Loder
AIM: To determine if there was a seasonal variation in adults undergoing total hip arthroplasty for end stage hip disease due to osteoarthritis (OA) or sequelae of developmental dysplasia of the hip (DDH). METHODS: The total hip registry from the author's institution for the years 1969 to 2013 was reviewed. The month of birth, age, gender, and ethnicity was recorded. Differences between number of births observed and expected in the winter months (October through February) and non-winter mo (March through September) were analyzed with the χ(2) test...
December 18, 2016: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28025728/semiautomatic-classification-of-acetabular-shape-from-three-dimensional-ultrasound-for-diagnosis-of-infant-hip-dysplasia-using-geometric-features
#18
Abhilash Rakkunedeth Hareendranathan, Dornoosh Zonoobi, Myles Mabee, Chad Diederichs, Kumaradevan Punithakumar, Michelle Noga, Jacob L Jaremko
PURPOSE: Developmental dysplasia of the hip (DDH) is a congenital deformity which in severe cases leads to hip dislocation and in milder cases to premature osteoarthritis. Image-aided diagnosis of DDH is partly based on Graf classification which quantifies the acetabular shape seen at two-dimensional ultrasound (2DUS), which leads to high inter-scan variance. 3D ultrasound (3DUS) is a promising alternative for more reliable DDH diagnosis. However, manual quantification of acetabular shape from 3DUS is cumbersome...
December 26, 2016: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28017958/theoretical-implications-of-periacetabular-osteotomy-in-various-dysplastic-acetabular-cartilage-defects-as-determined-by-finite-element-analysis
#19
Meng Xu, Wenrui Qu, Yanbing Wang, Lei Zhong, Zhe Zhu, Wei Li, Xin Zhao, Jincheng Wang, Yu Sun
BACKGROUND Different extents and locations of acetabular cartilage defect have been supposed to be a major cause of undesirable outcomes of periacetabular osteotomy (PAO) in patients with developmental dysplasia of the hip (DDH). This study aimed to verify whether different locations of cartilage deficiency affect the biomechanical environment in a three-dimensional model utilizing finite element analysis (FEA). MATERIAL AND METHODS We developed 3 DDH models - DDH-1 (normal shape), DDH-2 (superior defect), and DDH-3 (anterosuperior defect) - by deforming from a normal hip model...
December 26, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28004172/hydrophobic-ionic-liquids-for-quantitative-bacterial-cell-lysis-with-subsequent-dna-quantification
#20
Sabine Fuchs-Telka, Susanne Fister, Patrick-Julian Mester, Martin Wagner, Peter Rossmanith
DNA is one of the most frequently analyzed molecules in the life sciences. In this article we describe a simple and fast protocol for quantitative DNA isolation from bacteria based on hydrophobic ionic liquid supported cell lysis at elevated temperatures (120-150 °C) for subsequent PCR-based analysis. From a set of five hydrophobic ionic liquids, 1-butyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide was identified as the most suitable for quantitative cell lysis and DNA extraction because of limited quantitative PCR inhibition by the aqueous eluate as well as no detectable DNA uptake...
December 21, 2016: Analytical and Bioanalytical Chemistry
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