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JOURNAL ARTICLE
Juan-Ramón González-Rueda, Agustín Galparsoro-Catalán, Víctor-Manuel de Paz-Hermoso, Elena Riad-Deglow, Álvaro Zubizarreta-Macho, Jesús Pato-Mourelo, Sofía Hernández-Montero, Javier Montero-Martín
BACKGROUND: Analyze and compare the accuracy of zygomatic dental implant placement carried out using a static navigation surgery, a dynamic navigation surgery and an augmented reality appliance. MATERIAL AND METHODS: Eighty (80) zygomatic dental implants were randomly assigned to one of four study groups: A: static navigation implant surgery (n = 20) (GI); B: dynamic navigation implant surgery (n = 20) (NI); C: augmented reality appliance implant placement (n = 20) (ARI) and D: free hand technique (n = 20) (FHI)...
December 2023: Journal of Clinical and Experimental Dentistry
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JOURNAL ARTICLE
Victor X Mosquera, Adrian Muinelo-Paul, Oscar Pato-López, Alberto Bouzas-Mosquera, José J Cuenca-Castillo
OBJECTIVES: This study analyzes neocommissural alignment and the clinical and hemodynamic outcomes after transaxillary and transcarotid implantation of the Acurate neo2 transcatheter heart valve. METHODS: We performed a retrospective, single-center analysis of early outcomes after transaxillary and transcarotid implantation of the Acurate neo2 transcatheter heart valve. Primary outcomes were neocommisural alignment, in-hospital mortality, and valve hemodynamic performance...
December 2023: JTCVS techniques
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JOURNAL ARTICLE
Yu-Chun Chien, Ying-Chih Ko, Wen-Chu Chiang, Jen-Tang Sun, Sang Do Shin, Hideharu Tanaka, Sabariah Faizah Jamaluddin, Hao-Yang Lin, Matthew Huei-Ming Ma
BACKGROUND: Major trauma is a leading cause of unexpected death globally, with increasing age-adjusted death rates for unintentional injuries. Field triage schemes (FTSs) assist emergency medical technicians in identifying appropriate medical care facilities for patients. While full FTSs may improve sensitivity, step-by-step field triage is time-consuming. A simplified FTS (sFTS) that uses only physiological and anatomical criteria may offer a more rapid decision-making process. However, evidence for this approach is limited, and its performance in identifying all age groups requiring trauma center resources in Asia remains unclear...
December 14, 2023: American Journal of Emergency Medicine
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JOURNAL ARTICLE
Avishay Edri, Nimrod Ben-Haim, Astar Hailu, Nurit Brycman, Orit Berhani-Zipori, Julia Rifman, Sherri Cohen, Dima Yackoubov, Michael Rosenberg, Ronit Simantov, Hideshima Teru, Keiji Kurata, Kenneth Carl Anderson, Ayal Hendel, Aviad Pato, Yona Geffen
Natural killer (NK) cells are a vital component of cancer immune surveillance. They provide a rapid and potent immune response, including direct cytotoxicity and mobilization of the immune system, without the need for antigen processing and presentation. NK cells may also be better tolerated than T cell therapy approaches and are susceptible to various gene manipulations. Therefore, NK cells have become the focus of extensive translational research. Gamida Cell's nicotinamide (NAM) platform for cultured NK cells provides an opportunity to enhance the therapeutic potential of NK cells...
December 7, 2023: International Journal of Molecular Sciences
#25
JOURNAL ARTICLE
Yu-Chun Chien, Wen-Chu Chiang, Chi-Hsin Chen, Jen-Tang Sun, Sabariah Faizah Jamaluddin, Hideharu Tanaka, Matthew Huei-Ming Ma, Edward Pei-Chuan Huang, Mau-Roung Lin
BACKGROUND AND IMPORTANCE: This study compared the on-scene Glasgow Coma Scale (GCS) and the GCS-motor (GCS-M) for predictive accuracy of mortality and severe disability using a large, multicenter population of trauma patients in Asian countries. OBJECTIVE: To compare the ability of the prehospital GCS and GCS-M to predict 30-day mortality and severe disability in trauma patients. DESIGN: We used the Pan-Asia Trauma Outcomes Study registry to enroll all trauma patients >18 years of age who presented to hospitals via emergency medical services from 1 January 2016 to November 30, 2018...
December 13, 2023: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
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JOURNAL ARTICLE
Alfredo Madrid-García, Zulema Rosales-Rosado, Dalifer Freites-Nuñez, Inés Pérez-Sancristóbal, Esperanza Pato-Cour, Chamaida Plasencia-Rodríguez, Luis Cabeza-Osorio, Lydia Abasolo-Alcázar, Leticia León-Mateos, Benjamín Fernández-Gutiérrez, Luis Rodríguez-Rodríguez
The emergence of large language models (LLM) with remarkable performance such as ChatGPT and GPT-4, has led to an unprecedented uptake in the population. One of their most promising and studied applications concerns education due to their ability to understand and generate human-like text, creating a multitude of opportunities for enhancing educational practices and outcomes. The objective of this study is twofold: to assess the accuracy of ChatGPT/GPT-4 in answering rheumatology questions from the access exam to specialized medical training in Spain (MIR), and to evaluate the medical reasoning followed by these LLM to answer those questions...
December 13, 2023: Scientific Reports
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JOURNAL ARTICLE
Sabrina R Vollrath, Valéria M Lemos, João P Vieira, Alexandre M Garcia
Overfishing constitutes a major threat affecting marine fish population worldwide, including mullet species that have been exploited by fisheries during the reproductive migration in temperate and tropical latitudes for millennia. In the present study, we investigated the relationship of fishing intensity of mullet Mugil liza during its reproductive migration and the abundance of their juveniles in an essential nursery ground for the species in the southwest Atlantic Ocean. To carry out this analysis, we used a 23-year standardized long-term time series (1997-2019) of monthly abundance of M...
December 6, 2023: Marine Environmental Research
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JOURNAL ARTICLE
Catarina Jota Baptista, Fernanda Seixas, José M Gonzalo-Orden, Carla Patinha, Pedro Pato, Eduardo Ferreira da Silva, Luís J Merino-Goyenechea, Paula A Oliveira
Wild boars (Sus scrofa) are part of the hunting economy and are highly consumed in the Iberian Peninsula, including in the Castile and Leon regions. As zoonotic diseases, chemical pollutants in wild boars' internal tissues should be interpreted as evidence of environmental contamination and a matter of concern for animal, human and ecosystem health; in other words, a One Health concern. Twenty-eight wild boars' livers and kidneys (n = 28) from Castile and Leon were submitted to metal(loid) determination (As, Cd, Co, Cr, Cu, Ni, Pb, and Zn) with inductively coupled plasma mass spectrophotometry (ICP-MS) and histopathological exam...
December 6, 2023: Veterinary Research Communications
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REVIEW
Ángel-Orión Salgado-Peralvo, Naresh Kewalramani, Alba Pérez-Jardón, Jesús Pato-Mourelo, Adriana Castro-Calderón, Lorenzo Arriba-Fuente, Mario Pérez-Sayáns
Platelet-rich fibrin (PRF) is a second-generation platelet concentrate whose use in clinical practice has been widely disseminated. This has led to the development of several commercial protocols, creating great confusion as to the terminology and implications of each of them. This integrative review aims to identify the critical factors of each of the phases of the solid-based PRF matrix protocol and their possible influence on their macro- and microscopic characteristics. An electronic search of the MEDLINE database (via PubMed), Web of Science, Scopus, LILACS, and OpenGrey was carried out...
October 27, 2023: Medicina
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JOURNAL ARTICLE
Michał Romański, Joanna Giebułtowicz, Elżbieta Gniazdowska, Roman Piotrowski, Anna Żuk, Piotr Kułakowski, Jadwiga Paszkowska, Daria Myslitska, Jaroslaw Sczodrok, Grzegorz Garbacz, Dorota Danielak
A direct oral anticoagulant rivaroxaban fails to prevent stroke and systemic embolism in one-to-several percent of patients with nonvalvular atrial fibrillation (NVAF), but the reasons are unknown. The study used semi-mechanistic in vitro-in vivo prediction (IVIVP) modeling to explore the reasons for ineffective thrombosis prevention in NVAF patients. Steady-state drug concentrations in plasma were measured at 0 h (Ctrough ), 3 h (C3h ), and 12 h post-dosing in thirty-four patients treated with 20 mg rivaroxaban daily...
November 22, 2023: International Journal of Pharmaceutics
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JOURNAL ARTICLE
Nerea Gonzalez-Pato, Davide Blasi, Domna M Nikolaidou, Francesco Bertocchi, Jesús Cerdá, Francesca Terenziani, Nora Ventosa, Juan Aragó, Andrea Lapini, Jaume Veciana, Imma Ratera
Nanothermometers are emerging probes as biomedical diagnostic tools. Especially appealing are nanoprobes using NIR light in the range of biological transparency window (BTW) since they have the advantages of a deeper penetration into biological tissues, better contrast, reduced phototoxicity and photobleaching. This article reports the preparation and characterization of organic nanoparticles (ONPs) doped with two polychlorinated trityl radicals (TTM and PTM), as well as studies of their electronic and optical properties...
November 22, 2023: Small Methods
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JOURNAL ARTICLE
M J Maciá-Andreu, R Vaquero-Cristóbal, L Meroño, L Abenza-Cano, J A García-Roca, F J Cánovas-Álvarez, A Díaz-Aroca, L Capranica, M Stanescu, A Pereira, M Doupona, F Mendes, A Figueiredo, E Isidori, A Sánchez-Pato, A Leiva-Arcas
The objective of this study was to analyze the perceived barriers to dual career success and athletic identity of student-athletes according to disability type and level of professionalization. The final sample consisted of 203 student-athletes with disabilities from five European countries. The questionnaires used were ESTPORT, EBBS and AIMS. Depending on disability type, it was found that student-athletes with hearing and physical impairment showed the highest difficulty in reconciling sports and studies (p = 0...
November 22, 2023: Scientific Reports
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JOURNAL ARTICLE
Irina Horváthné Pató, Tamás Szekeres, Szilvia Kresznerits, Dóra Perczel-Forintos
INTRODUCTION: Suicide attempts and their consequences have been the leading causes of death among prisoners. Meta-analyses suggest that the main risk factors are current suicidal ideation, the presence of a mental disorder, high perceived stress levels, previous suicidal attempts or self-harm, and institutional and criminogenic variables. Empirical evidence is consistent with the integrated motivational-volitional model of suicidality, which also emphasizes the role of impulsivity in suicidal behaviour...
2023: Psychiatria Hungarica: A Magyar Pszichiátriai Társaság Tudományos Folyóirata
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JOURNAL ARTICLE
James J Crowley, Carolina Cappi, Marcos E Ochoa-Panaifo, Renee M Frederick, Minjee Kook, Andrew D Wiese, Diana Rancourt, Elizabeth G Atkinson, Paola Giusti-Rodriguez, Jacey L Anderberg, Jonathan S Abramowitz, Victor R Adorno, Cinthia Aguirre, Gilberto S Alves, Gustavo S Alves, NaEshia Ancalade, Alejandro A Arellano Espinosa, Paul D Arnold, Daphne M Ayton, Izabela G Barbosa, Laura Marcela Barón Castano, Cynthia N Barrera, María Celeste Berardo, Dayan Berrones, John R Best, Tim B Bigdeli, Christie L Burton, Joseph D Buxbaum, Jennifer L Callahan, Maria Cecília B Carneiro, Sandra L Cepeda, Evelyn Chazelle, Jessica M Chire, Macarena Churruca Munoz, Pamela Claisse Quiroz, Journa Cobite, Jonathan S Comer, Daniel L Costa, Jennifer Crosbie, Victor O Cruz, Guillermo Dager, Luisa F Daza, Anabel de la Rosa-Gómez, Daniela Del Río, Fernanda Z Delage, Carolina B Dreher, Lucila Fay, Tomas Fazio, Ygor A Ferrão, Gabriela M Ferreira, Edith G Figueroa, Leonardo F Fontenelle, Diego A Forero, Daniele T H Fragoso, Bharathi S Gadad, Sheldon R Garrison, Andres González, Laura D Gonzalez, Marco A González, Polaris Gonzalez-Barrios, Wayne K Goodman, Dorothy E Grice, Jerry Guintivano, Daniel G Guttfreund, Andrew G Guzick, Matthew W Halvorsen, Joseph D Hovey, Hailiang Huang, Jonathan Irreño-Sotomonte, Reinhard Janssen-Aguilar, Matias Jensen, Alexandra Z Jimenez Reynolds, Joali Alexandra Juárez Lujambio, Nasim Khalfe, Madison A Knutsen, Caleb Lack, Nuria Lanzagorta, Monicke O Lima, Melanie O Longhurst, David A Lozada Martinez, Elba S Luna, Andrea H Marques, Molly S Martinez, Maria de Los Angeles Matos, Caitlyn E Maye, Joseph F McGuire, Gabriela Menezes, Charlene Minaya, Tomás Miño, Sara M Mithani, Circe Montes de Oca, Alonso Morales-Rivero, Maria E Moreira-de-Oliveira, Olivia J Morris, Sandra I Muñoz, Zainab Naqqash, Ambar A Núñez Bracho, Belinda E Núñez Bracho, Maria Corina Ochoa Rojas, Luis A Olavarria Castaman, Trinidad Olivos Balmaceda, Iliana Ortega, Darpan I Patel, Ainsley K Patrick, Mariel Paz Y Mino, Jose L Perales Orellana, Bárbara Perdigão Stumpf, Tamara Peregrina, Tania Pérez Duarte, Kelly L Piacsek, Maritza Placencia, María Belén Prieto, Lucas C Quarantini, Yana Quarantini-Alvim, Renato T Ramos, Iaroslava C Ramos, Vanessa R Ramos, Kesley A Ramsey, Elise V Ray, Margaret A Richter, Bradley C Riemann, Juan C Rivas, Maria C Rosario, Camilo J Ruggero, Angel A Ruiz-Chow, Alejandra Ruiz-Velasco, Melisa N Sagarnaga, Aline S Sampaio, Leonardo C Saraiva, Russell J Schachar, Sophie C Schneider, Ethan J Schweissing, Laura D Seligman, Roseli G Shavitt, Keaton J Soileau, S Evelyn Stewart, Shaina B Storch, Emily R Strouphauer, Vissente Tapia Cuevas, Kiara R Timpano, Beatriz Treviño-de la Garza, Alexie Vallejo-Silva, Javier Vargas-Medrano, María I Vásquez, Guadalupe Vidal Martinez, Saira A Weinzimmer, Mauricio A Yanez, Gwyneth Zai, Lina M Zapata-Restrepo, Luz M Zappa, Raquel M Zepeda-Burgos, Anthony W Zoghbi, Euripedes C Miguel, Carolyn I Rodriguez, Mayra C Martinez Mallen, Pablo R Moya, Tania Borda, María Beatriz Moyano, Manuel Mattheisen, Stacey Pereira, Gabriel Lázaro-Muñoz, Karen G Martinez-Gonzalez, Michele T Pato, Humberto Nicolini, Eric A Storch
Obsessive-compulsive disorder (OCD) is a debilitating psychiatric disorder. Worldwide, its prevalence is ~2% and its etiology is mostly unknown. Identifying biological factors contributing to OCD will elucidate underlying mechanisms and might contribute to improved treatment outcomes. Genomic studies of OCD are beginning to reveal long-sought risk loci, but >95% of the cases currently in analysis are of homogenous European ancestry. If not addressed, this Eurocentric bias will result in OCD genomic findings being more accurate for individuals of European ancestry than other ancestries, thereby contributing to health disparities in potential future applications of genomics...
November 9, 2023: American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics
#35
JOURNAL ARTICLE
Johanne E Spreckels, Asier Fernández-Pato, Marloes Kruk, Alexander Kurilshikov, Sanzhima Garmaeva, Trishla Sinha, Hiren Ghosh, Hermie Harmsen, Jingyuan Fu, Ranko Gacesa, Alexandra Zhernakova
Human milk microbiome studies are currently hindered by low milk bacterial/human cell ratios and often rely on 16S rRNA gene sequencing, which limits downstream analyses. Here, we aimed to find a method to study milk bacteria and assess bacterial sharing between maternal and infant microbiota. We tested four DNA isolation methods, two bacterial enrichment methods and three sequencing methods on mock communities, milk samples and negative controls. Of the four DNA isolation kits, the DNeasy PowerSoil Pro (PS) and MagMAX Total Nucleic Acid Isolation (MX) kits provided consistent 16S rRNA gene sequencing results with low contamination...
November 9, 2023: ISME Commun
#36
JOURNAL ARTICLE
Szu-Han Chen, Meng-Chang Lee, Po-Yuan Wang, Matthew Huei-Ming Ma, Sang Do Shin, Jen-Tang Sun, Sabariah Faizah Jamaluddin, Hideharu Tanaka, Do Ngoc Son, Ki Jeong Hong, Wei-Chieh Tseng, Wen-Chu Chiang
BACKGROUND: To prevent school injuries, thorough epidemiological data is an essential foundation. We aimed to investigate the characteristics of school injuries in Asia and explore risk factors for major trauma. METHODS: This retrospective study was conducted in the participating centers of the Pan-Asian Trauma Outcome Study from October 2015 to December 2020. Subjects who reported "school" as the site of injury were included. Major trauma was defined as an Injury Severity Score (ISS) value of ≥16...
November 7, 2023: Pediatric Research
#37
JOURNAL ARTICLE
Victoria Sook Keng Tung, Fasil Mathews, Marina Boruk, Gabrielle Suppa, Robert Foronjy, Michele T Pato, Carlos N Pato, James A Knowles, Oleg V Evgrafov
The study of neurodevelopmental molecular mechanisms in schizophrenia requires the development of adequate biological models such as patient-derived cells and their derivatives. We previously utilized cell lines with neural progenitor properties (CNON) derived from the superior or middle turbinates of patients with schizophrenia and control groups to study schizophrenia-specific gene expression. In this study, we analyzed single-cell RNA seq data from two CNON cell lines (one derived from an individual with schizophrenia (SCZ) and the other from a control group) and two biopsy samples from the middle turbinate (MT) (also from an individual with SCZ and a control)...
October 19, 2023: International Journal of Molecular Sciences
#38
JOURNAL ARTICLE
M Sánchez-Díaz, Á Flórez, M Ara-Martín, S Arias-Santiago, R Botella-Estrada, J Cañueto, G Carretero-Hernández, P Coto-Segura, E de Eusebio-Murillo, F J García-Latasa de Araníbar, V García-Patos Briones, J Gardeazabal García, C Gómez-Fernández, S Hernández-Ostiz, R Izu Belloso, A López-Ávila, P Manchado López, A Martín-Santiago, I Martinez De Espronceda Ezquerro, A Mateu-Puchades, P Mercader-García, J Notario Rosa, L Palacio Aller, C Pérez-Hortet, L Quintana-Castanedo, R Rivera, V Rocamora Duran, I M Rodríguez-Nevado, R Ruiz-Villaverde, J Suárez, L Trasobares-Marugán, C Vizán-de Uña, I Yanguas, A Zulaica-Garate, I García-Doval, M Á Descalzo, M Grau-Pérez, J M Carrascosa-Carrillo
BACKGROUND AND OBJECTIVE: Although the Spanish Ministry of Health prepares national therapeutic positioning reports (TPRs) and drug reimbursement policies, each of the country's 17 autonomous communities is responsible for health care services and prescription requirements in its territory. The aim of the EQUIDAD study was to describe and explore potential differences in prescription requirements for new dermatology drugs across the autonomous communities. MATERIAL AND METHODS: Cross-sectional study conducted in April and May, 2023...
October 25, 2023: Actas Dermo-sifiliográficas
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JOURNAL ARTICLE
Emma Beltrán Catalán, Noé Brito García, Esperanza Pato Cour, Santiago Muñoz Fernández, Alejandro Gómez Gómez, David Díaz Valle, Marisa Hernández Garfella, Félix Manuel Francisco Hernández, M Del Mar Trujillo Martín, Lucía Silva Fernández, Gemma Villanueva, Julio Suárez Cuba, Ricardo Blanco
OBJECTIVE: To develop evidence-based expert-consensus recommendations for the management of non-infectious, non-neoplastic, non-demyelinating disease associated uveitis. METHODS: Clinical research questions relevant to the objective of the document were identified, and reformulated into PICO format (patient, intervention, comparison, outcome) by a panel of experts selected based on their experience in the field. A systematic review of the available evidence was conducted, and evidence was graded according to GRADE (Grading of Recommendations Assessment, Development, and Evaluation) criteria...
November 2023: Reumatología clinica
#40
JOURNAL ARTICLE
Faisal S Jehan, Sangrag Ganguli, Areeba Saif, Niklas E Hase, Paramita S Nayak, Apoorve Nayyar, Hassan Aziz
INTRODUCTION: Information about condition(s) being present at time of surgery (PATOS) in the American College of Surgeons (ASC) National Surgical Quality Improvement Program (NSQIP) database can influence the postoperative complication rates after liver surgeries. Here, we compare the postoperative complication rates with and without taking condition(s) being PATOS into account. METHODS: We retrospectively reviewed the ACS NSQIP Participant User Files (PUFs) from 2015 through 2019...
October 1, 2023: American Journal of Surgery
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