keyword
https://read.qxmd.com/read/38435949/exploring-individualized-approaches-to-managing-vancouver-b-periprosthetic-femoral-fractures-insights-from-a-comprehensive-case-series-analysis
#1
JOURNAL ARTICLE
Adrian Cursaru, Mihnea Popa, Bogdan Cretu, Sergiu Iordache, Georgian L Iacobescu, Razvan Spiridonica, Angel Rascu, Bogdan Serban, Catalin Cirstoiu
The increasing prevalence of periprosthetic femoral fractures, specifically in the vicinity of the hip, has emerged as a significant issue in recent times. Consequently, there is a need for a thorough examination to enhance the effectiveness of management and treatment approaches. The findings of this study emphasize a significant disparity in the occurrence and characteristics of these fractures, and the multiple cases have highlighted the efficacy of various treatment strategies, such as open reduction and internal fixation, as well as the utilization of cortical strut allografts...
January 2024: Curēus
https://read.qxmd.com/read/38411105/the-impact-of-social-determinants-of-health-on-the-treatment-of-distal-radius-fracture
#2
JOURNAL ARTICLE
Graham Grogan, Kristen L Stephens, Jesse Chou, Jasmina Abdalla, Ryan Wagner, Kacy J Peek, Aaron M Freilich, Brent R DeGeorge
BACKGROUND: Disparities in social determinants of health (SDH) have been shown to play an increasingly important role in the equitable delivery of health care. Distal radius fractures (DRFs) are among the most common upper-extremity injuries encountered. This study aims to examine the influence of economic, educational, social, environmental, and healthcare disparities on management of these injuries. METHODS: PearlDiver Mariner insurance claims database was analyzed for treatment patterns of DRF in patients aged 18 to 65 years based on the presence or absence of social determinants of health disparities (SDHDs)...
February 27, 2024: Hand: Official Journal of the American Association for Hand Surgery
https://read.qxmd.com/read/38378724/the-gaze-of-schizophrenia-patients-captured-by-bottom-up-saliency
#3
JOURNAL ARTICLE
Petr Adámek, Dominika Grygarová, Lucia Jajcay, Eduard Bakštein, Petra Fürstová, Veronika Juríčková, Juraj Jonáš, Veronika Langová, Iryna Neskoroďana, Ladislav Kesner, Jiří Horáček
Schizophrenia (SCHZ) notably impacts various human perceptual modalities, including vision. Prior research has identified marked abnormalities in perceptual organization in SCHZ, predominantly attributed to deficits in bottom-up processing. Our study introduces a novel paradigm to differentiate the roles of top-down and bottom-up processes in visual perception in SCHZ. We analysed eye-tracking fixation ground truth maps from 28 SCHZ patients and 25 healthy controls (HC), comparing these with two mathematical models of visual saliency: one bottom-up, based on the physical attributes of images, and the other top-down, incorporating machine learning...
February 20, 2024: Schizophrenia (Heidelb)
https://read.qxmd.com/read/38317534/increased-time-to-fixation-after-traumatic-spinal-cord-injury-influenced-by-race-and-insurance-status
#4
JOURNAL ARTICLE
Jon Raso, Pramod Kamalapathy, Eric Solomon, Elizabeth Driskill, Kristina Kurker, Aditya Joshi, Hamid Hassanzadeh
STUDY DESIGN: Retrospective Cohort Study. OBJECTIVES: Although the optimal timing of surgical intervention for traumatic spinal cord injury (TSCI) is controversial, early intervention has been recognized as being beneficial in several studies. The objective of this study was to evaluate the socioeconomic factors that may delay time to surgical fixation in the management of TSCI. METHODS: The present study utilized the Trauma Quality Improvement Program (TQIP) dataset to identify patients aged greater than 18 undergoing spinal fusion for TSCI from 2007-2016...
February 5, 2024: Global Spine Journal
https://read.qxmd.com/read/38316570/analgesic-effectiveness-of-continuous-versus-single-injection-adductor-canal-block-in-addition-to-continuous-popliteal-sciatic-nerve-block-for-bimalleolar-and-trimalleolar-ankle-fracture-surgery-prospective-randomized-controlled-trial
#5
JOURNAL ARTICLE
Young Uk Park, Han Bum Joe, Jong Wha Lee, Young Wook Seo
BACKGROUND: The adductor canal block is a well-known procedure for controlling postoperative pain after medial malleolus fracture surgery. Continuous nerve block is a viable option for blocking pain for a longer period although the literature on this subject is scarce. Therefore, this study aimed to compare continuous adductor canal block (cACB) group to single-injection adductor canal block (sACB) group in those with bimalleolar or trimalleolar ankle fractures. The procedure was performed in addition to a continuous sciatic nerve block for postoperative pain relief and patient satisfaction...
February 5, 2024: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://read.qxmd.com/read/38299757/unusual-electronic-structures-of-an-electron-transfer-series-of-cr-%C3%AE-%C3%AE-1-%C3%AE-1-n2-cr-0-1-2
#6
JOURNAL ARTICLE
Gao-Xiang Wang, Chunxiao Shan, Wang Chen, Botao Wu, Peng Zhang, Junnian Wei, Zhenfeng Xi, Shengfa Ye
In dinitrogen (N2) fixation chemistry, bimetallic end-on bridging N2 complexes M(μ-η1:η1-N2)M can split N2 into terminal nitrides and hence attract great attention. To date, only 4d and 5d transition complexes, but none of 3d counterparts, could realize such a transformation. Likewise, complexes {[Cp*Cr(dmpe)]2(μ-N2)}0/1+/2+ (1-3) are incapable to cleave N2, in contrast to their Mo congeners. Remarkably, cross this series the N-N bond length of the N2 ligand and the N-N stretching frequency exhibit unprecedented nonmonotonic variations, and complexes 1 and 2 in both solid and solution states display rare thermally activated ligand-mediated two-center spin transitions (STs), distinct from discrete dinuclear spin crossovers...
February 1, 2024: Angewandte Chemie
https://read.qxmd.com/read/38294540/image-guided-percutaneous-cholecystostomy-challenging-the-norms
#7
JOURNAL ARTICLE
Nikolaos-Achilleas Arkoudis, Lazaros Reppas, Stavros Spiliopoulos
Image-guided percutaneous cholecystostomy (IGPC) is a widely recognized and regularly employed procedure in numerous institutions, serving as an indispensable cornerstone in the management of patients with acute cholecystitis. The most up-to-date literature has found that the transperitoneal route is at least as safe as the transhepatic route and that both the trocar and Seldinger techniques are equally safe and effective. The above novel insights may offer reassurance and alleviate concerns among operators performing IGPC by dispelling the fixation on previously established beliefs and thus providing flexibility, which lightens the load on the operator...
January 31, 2024: Abdominal Radiology
https://read.qxmd.com/read/38235858/clinical-efficacy-analysis-of-minimally-invasive-intramedullary-nailing-in-the-treatment-of-humeral-shaft-fractures-combined-with-radial-nerve-injury
#8
JOURNAL ARTICLE
S-Y Shi, X-L Du, X-H Ou
OBJECTIVE: The aim of this study was to research the therapeutic effectiveness of radial nerve damage paired with a humeral shaft fracture and intramedullary nailing. PATIENTS AND METHODS: Retrospective research was performed on the medical records of 58 individuals who had humeral shaft fractures and radial nerve injuries. The admission period was between June 1, 2020, and June 31, 2022. All study subjects that satisfied the requirements for inclusion were separated, using the random number table approach, into two groups: one for internal fixation (group N), which included 29 cases, and one for minimally invasive procedures (group W), which included 29 patients...
January 2024: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/38233925/effectiveness-of-bone-grafting-versus-cannulated-screw-fixation-in-the-treatment-of-posterolateral-tibial-plateau-compression-fractures-with-concomitant-acl-injury-a-comparative-study
#9
JOURNAL ARTICLE
Yang Yang, Xiaofang Lin, Jianmin Zhang, Hanlong Xin, Dawei Han, Qingguo Zhang, Xiaobo Zhou
BACKGROUND: Posterolateral tibial plateau compression fractures (PTPCF) are one of the significant factors leading to knee instability and anterior cruciate ligament (ACL) reconstruction failure. The effectiveness of fixation for such cases without the use of metal implants remains inconclusive. The aim of this study is to investigate whether the fixation with isolated bone grafting is stable enough for the treatment of PTPCF with concomitant ACL injuries. METHODS: This retrospective study analyzed patients treated for concomitant ACL injuries and PTPCF in authors' institution...
January 17, 2024: Journal of Orthopaedic Surgery and Research
https://read.qxmd.com/read/38181226/drift-drives-the-evolution-of-chromosome-number-i-the-impact-of-trait-transitions-on-genome-evolution-in-coleoptera
#10
JOURNAL ARTICLE
Heath Blackmon, Michelle M Jonika, James M Alfieri, Jeffery P Demuth
Chromosomal mutations such as fusions and fissions are often thought to be deleterious, especially in heterozygotes (underdominant), and consequently are unlikely to become fixed. Yet, many models of chromosomal speciation ascribe an important role to chromosomal mutations. When the effective population size (Ne) is small, the efficacy of selection is weakened, and the likelihood of fixing underdominant mutations by genetic drift is greater. Thus, it is possible that ecological and phenotypic transitions that modulate Ne facilitate the fixation of chromosome changes, increasing the rate of karyotype evolution...
January 5, 2024: Journal of Heredity
https://read.qxmd.com/read/38153736/medicare-eligibility-and-racial-and-ethnic-disparities-in-operative-fixation-for-distal-radius-fracture
#11
JOURNAL ARTICLE
Trista M Benítez, Zhongzhe Ouyang, Alexander N Khouri, Joseph N Fahmy, Lu Wang, Kevin C Chung
IMPORTANCE: Medicare provides near-universal health insurance to US residents aged 65 years or older. How eligibility for Medicare coverage affects racial and ethnic disparities in operative management after orthopedic trauma is poorly understood. OBJECTIVE: To assess the association of Medicare eligibility with racial and ethnic disparities in open reduction and internal fixation (ORIF) after distal radius fracture (DRF). DESIGN, SETTING, AND PARTICIPANTS: This retrospective cohort study with a regression discontinuity design obtained data from the Healthcare Cost and Utilization Project all-payer statewide databases for Florida, Maryland, and New York...
December 1, 2023: JAMA Network Open
https://read.qxmd.com/read/38130715/commbini-an-experimentally-informed-computational-model-of-macrophage-dynamics-in-the-bone-injury-immunoresponse
#12
JOURNAL ARTICLE
Edoardo Borgiani, Gabriele Nasello, Liesbeth Ory, Tim Herpelinck, Lisanne Groeneveldt, Christian H Bucher, Katharina Schmidt-Bleek, Liesbet Geris
Bone fracture healing is a well-orchestrated but complex process that involves numerous regulations at different scales. This complexity becomes particularly evident during the inflammatory stage, as immune cells invade the healing region and trigger a cascade of signals to promote a favorable regenerative environment. Thus, the emergence of criticalities during this stage might hinder the rest of the process. Therefore, the investigation of the many interactions that regulate the inflammation has a primary importance on the exploration of the overall healing progression...
2023: Frontiers in Immunology
https://read.qxmd.com/read/38106428/disparate-viral-pandemics-from-covid19-to-monkeypox-and-beyond-a-simple-effective-and-universal-therapeutic-approach-hiding-in-plain-sight
#13
REVIEW
Howard M Johnson, Chulbul M Ahmed
The field of antiviral therapeutics is fixated on COVID19 and rightly so as the fatalities at the height of the pandemic in the United States were almost 1,000,000 in a twelve month period spanning parts of 2020/2021. A coronavirus called SARS-CoV2 is the causative virus. Development of a vaccine through molecular biology approaches with mRNA as the inducer of virus spike protein has played a major role in driving down mortality and morbidity. Antivirals have been of marginal value in established infections at the level of hospitalization...
2023: Frontiers in Immunology
https://read.qxmd.com/read/38101970/how-good-is-good-enough-lessons-learned-from-review-of-outcomes-of-50-patients-following-extraoral-open-reduction-and-internal-fixation-of-condylar-neck-and-base-fractures-at-a-regional-major-trauma-centre
#14
JOURNAL ARTICLE
Julian Leow, Rebecca Exley, Simon Holmes, Nabeel Bhatti
The management of mandibular fractures is routine owing to their frequency, particularly those of the mandibular condyle, which are invariably common. Notwithstanding disparities in the literature, the international consensus towards which fractures of the mandibular condyle benefit from open surgical intervention is almost universally accepted. Closed reduction or non-operative management may be utilised in certain circumstances. Whilst outcome research has addressed complications with respect to operative side effects, outcomes related to the quality of bone repair and the setting in which this is delivered have not been universally addressed...
November 27, 2023: British Journal of Oral & Maxillofacial Surgery
https://read.qxmd.com/read/38090313/door-to-door-in-24-factors-that-allow-surgical-stabilization-of-rib-fractures-within-24-hours-of-admission
#15
JOURNAL ARTICLE
Kiara Leasia, Jonne T H Prins, Ryan Lawless, Clay Cothren Burlew, Ernest E Moore, Barry Platnick, Lakshmipriya Karamsetty, Fredric M Pieracci
BACKGROUND: Surgical stabilization of rib fractures (SSRF) should be performed early after injury. Factors that influence timing remain unknown. Our objective was to identify inherent variables that allow for early identification and treatment. We hypothesized that certain demographic, injury, and logistical factors are associated with SSRF <24 hours from admission. METHODS: Retrospective review from an urban level 1 trauma center (10/2010-8/2019). Patients were grouped as SSRF <24 hours from admission vs...
November 30, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/38066529/surgical-management-practice-of-pelvic-organ-prolapse-among-ethiopian-gynecologists-2021-a-descriptive-study
#16
JOURNAL ARTICLE
Zelalem Ayichew Workineh, Birhanu Abera Ayana, Kiros Terefe Gashaye, Solomon Berhe Wubneh, Belayneh Ayanaw Kassie
INTRODUCTION: Pelvic Organ Prolapse is the descent of one or more of the anterior vaginal wall, posterior vaginal wall, the uterus, or the apex of the vagina. Surgical intervention addresses both anatomical defect and associated symptoms. The landscape of prolapse surgery has been evolving constantly over years. Emerging evidences either support or challenge existing surgical treatment options, making urogynecology a dynamic field. In Ethiopia, the surgical management of pelvic organ prolapse has transitioned from abdominal to vaginal hysterectomy, supplemented later by McCall's culdoplasty...
December 8, 2023: BMC Women's Health
https://read.qxmd.com/read/38043303/disparities-and-mechanisms-of-carbon-and-nitrogen-conversion-during-food-waste-composting-with-different-bulking-agents
#17
JOURNAL ARTICLE
Wuji Huang, Hongyu Shi, Qin Weng, Shang Ding, Liping Lou
The low C/N ratio, high moisture content, and low porosity of food waste require the addition of bulking agents for adjustment during the composting process. However, the effect and mechanism of different bulking agents on the reduction of carbon and nitrogen losses are unclear. Therefore, this study conducted experiments to evaluate and clarify the differences in carbon and nitrogen transformation between sawdust, rice husk and wheat bran in food waste composting. The results showed that the addition of bulking agents promoted the conversion of carbon and nitrogen into total organic carbon (TOC) and total organic nitrogen (TON) rather than CO2 and NH3 ...
December 2, 2023: Journal of Environmental Management
https://read.qxmd.com/read/38031238/effects-of-hazards-and-sensation-seeking-on-intermediate-swimming-college-students-hazard-perceptions
#18
JOURNAL ARTICLE
Hui Zhang, Li Zi Yun, Shi Luo
BACKGROUND: According to the Global Report on Drowning: Preventing a Leading Killer and Preventing Drowning: An Implementation Guide, two documents released by the World Health Organization in 2014 and 2017, respectively, 372,000 people drown each year globally (approximately 42 per hour), half of whom are below 25 years old. Chinese adolescents aged 18-24 years are the main victim group. Intermediate swimming college students are more susceptible to risk-taking behavior and drowning while swimming...
November 29, 2023: Brain and Behavior
https://read.qxmd.com/read/37964170/learning-curve-of-junior-surgeons-in-robot-assisted-pedicle-screw-placement-a-comparative-cohort-study
#19
JOURNAL ARTICLE
Fan Feng, Xiuyuan Chen, Zude Liu, Yingchao Han, Hao Chen, Quan Li, Lifeng Lao, Hongxing Shen
OBJECTIVE: Robot-assisted technology has been gradually applied to pedicle screw placement in spinal surgery. This study was designed to detailedly evaluate the learning curve of junior surgeons in robot-assisted spine surgery. METHODS: From December 2020 to February 2022, 199 patients requiring surgical treatment with posterior pedicle screw fixation were prospectively recruited into the study. The patients were randomized to the robot-assisted group (the RA group) or the conventional freehand group (the CF group)...
November 14, 2023: European Spine Journal
https://read.qxmd.com/read/37954698/differences-in-regional-anesthesia-utilization-by-hospital-region-in-the-united-states
#20
JOURNAL ARTICLE
Alexander Beletsky, Morgan Currie, Jonathan Shen, Hunter Brooks, Mahesh Desilva, Nutan Winston, Rodney A Gabriel
BACKGROUND: Regional anesthesia has been associated with improved postoperative outcomes. Disparities in regional anesthesia utilization exist; however, no studies have examined utilization rates as a function of hospital region. METHODS: A national hospital database (Hospital Corporation of America {HCA}) was queried for patients aged 18 years or older that received selected surgical procedure codes between January 2016 and June 2021. Surgical procedures included were total knee arthroplasty (TKA), total shoulder arthroplasty (TSA), anterior cruciate ligament reconstruction (ACLR), carpal tunnel release, total abdominal hysterectomy (TAH), open reduction and internal fixation (ORIF) of the ankle, and arteriovenous (AV) fistula creation...
October 2023: Curēus
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