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https://www.readbyqxmd.com/read/29644239/the-correlation-between-changes-in-biochemical-parameters-and-central-macular-thickness-in-patients-with-non-proliferative-diabetic-retinopathy
#1
Ayse Gul Kocak Altintas, Bayram Gulpamuk, Veysel Cankurtaran, Cagri Ilhan, Mehmet Citirik
This study aimed at evaluating the correlation between changes in Hemoglobin A1c (HbA1c) and fasting serum lipids, and Central Macular Thickness (CMT) in patients with Non-Proliferative Diabetic Retinopathy (NPDR). In the current research, both eyes of 68 patients with mild or moderate NPDR, without clinically significant macular edema, were studied. Levels of fasting serum lipids, HbAlc, and CMT were measured during the first visit and at the end of the follow-up period (3 months). For statistical analysis, CMTs of each eye were studied and the correlation of changes was investigated...
2018: Medical Hypothesis, Discovery and Innovation in Ophthalmology
https://www.readbyqxmd.com/read/29642939/elimination-of-onchocerciasis-from-colombia-first-proof-of-concept-of-river-blindness-elimination-in-the-world
#2
Rubén Santiago Nicholls, Sofía Duque, Luz Adriana Olaya, Myriam Consuelo López, Sol Beatriz Sánchez, Alba Lucía Morales, Gloria Inés Palma
BACKGROUND: Onchocerciasis is a chronic parasitic infection originally endemic in 13 discrete regional foci distributed among six countries of Latin America (Brazil, Colombia, Ecuador, Guatemala, Mexico and Venezuela). In Colombia, this disease was discovered in 1965 in the Pacific Coast of the country. The National Onchocerciasis Elimination Program was established in 1993 with the aim of eliminating disease morbidity and infection transmission. In 2013, the World Health Organization (WHO) verified Colombia as free of onchocerciasis, becoming the first country in the world to reach such a goal...
April 11, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29626669/the-effects-of-feeding-lactobacillus-pentosus-on-growth-immunity-and-disease-resistance-in-haliotis-discus-hannai-ino
#3
Gao Xiaolong, Zhang Mo, Li Xian, Han Yin, Wu Fucun, Liu Ying
To study the effects of probiotic-added food on the survival and growth of abalone (Haliotis discus hannai Ino), the expression levels of nonspecific immune genes and the anti-Vibrio parahaemolyticus infection were examined. During an 8-week culturing experiment in an indoor aquarium and a 2-week V. parahaemolyticus artificial infection experiment, the control group was fed with untreated food once a day, while the experimental groups (L1, L2 and L3) were fed with Lactobacillus pentosus added food. The concentration of probiotics in the experimental food was 103  cfu/g (L1), 105  cfu/g (L2) and 107  cfu/g (L3), respectively...
April 4, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29614090/intra-abdominal-pressure-vertebral-column-length-and-spread-of-spinal-anesthesia-in-parturients-undergoing-cesarean-section-an-observational-study
#4
Ting-Ting Ni, Ying Zhou, An-Cui Yong, Lu Wang, Qing-He Zhou
BACKGROUND: In parturients with increased physiologically intra-abdominal pressure (IAP) and a short stature, a greater cephalad spread of spinal anesthesia is often observed after a fixed amount of plain bupivacaine is administered. Therefore, we designed this prospective study to test whether IAP and vertebral column length (VCL) were predictors of spinal spread in parturients undergoing a cesarean section. METHODS: A total of 113 parturients, all undergoing elective cesarean sections with single-shot spinal anesthesia, were enrolled...
2018: PloS One
https://www.readbyqxmd.com/read/29605026/visceral-adiposity-but-not-subcutaneous-fat-associated-with-improved-outcome-of-patients-with-acute-cholecystitis
#5
Eyal Leibovitz, Nadav Ben-David, Lea Shibanov, Sorin Elias, Mordechai Shimonov
BACKGROUND: The aim of this study to study the effect of visceral and subcutaneous fat tissue mass on short- and long-term prognosis of patients with acute calculus cholecystitis (ACC). METHODS: Retrospective analysis of medical records. Included were all patients admitted because of ACC. Computed tomography images at the level of L3 were analyzed for body composition using designated software (Slice-O-matic; TomoVision, Montreal, Quebec, Canada). General linear model was used to analyze the effect of body composition on length of hospital stay, and Cox regression analysis was used to ascertain the effect of the different parameters on 1-y survival...
May 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29603915/examining-the-association-between-adiposity-and-biochemical-recurrence-after-radical-prostatectomy
#6
Ross J Mason, Stephen A Boorjian, Bimal Bhindi, Laureano Rangel, Igor Frank, R Jeffrey Karnes, Matthew K Tollefson
INTRODUCTION: Herein we examined the association between adiposity, as measured with computed tomography (CT), and biochemical recurrence (BCR) after RP. METHODS: Using axial CT images, preoperative fat mass index (FMI) was calculated for 698 men who underwent RP from 2007-2010 by using measurements of total surface area of adipose tissue at the L3 level. Obesity was classified according to NHANES standards for obesity (FMI >9 kg/m2 ). The associations between obesity and the distribution of adiposity (visceral vs...
March 19, 2018: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29603340/a-novel-stepwise-model-of-intervertebral-disc-degeneration-with-intact-annulus-fibrosus-to-test-regeneration-strategies
#7
Gianluca Vadalà, Fabrizio Russo, Francesca De Strobel, Marco Bernardini, Giulia De Benedictis, Caterina Cattani, Luca Denaro, Matteo D'Este, David Eglin, Mauro Alini, Vincenzo Denaro
Novel preclinical models that do not damage the annulus fibrosus (AF) of the intervertebral disc are required to study the efficacy of new regenerative strategies for the nucleus pulposus (NP). The aim of the study was to characterize a preclinical ovine model of intervertebral disc degeneration (IDD) induced by endplate (EP) damage and repair via the transpedicular approach, with or without partial nucleotomy, whilst keeping the AF intact. Twelve adult sheep were used. By the transpedicular approach, a 2mm tunnel was drilled to the NP through the EP...
March 30, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29595411/comparison-of-relative-and-absolute-values-of-magnetic-resonance-imaging-in-the-diagnosis-of-spinal-epidural-lipomatosis
#8
Yuxi Ge, Xiaohan Yang, Yaqian You, Yinghua Xuan, Gen Yan
Objective To describe spinal epidural lipomatosis (SEL) of the lumbar region and evaluate the relative versus absolute values of epidural fat (EF) to determine which is more appropriate when using magnetic resonance imaging (MRI). Design Comparative study. Setting Hospital. Participants Eight SEL patients and 40 healthy adults. Interventions MRI measurement of EF. Outcome Measures The MRI-based EF thickness, cutoff value, and coefficient of variation (CV) were calculated. Frequency distribution maps for the absolute EF value and the relative EF/DuS value were created...
March 29, 2018: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/29582133/marrow-adipose-tissue-in-older-men-association-with-visceral-and-subcutaneous-fat-bone-volume-metabolism-and-inflammation
#9
Ebrahim Bani Hassan, Oddom Demontiero, Sara Vogrin, Alvin Ng, Gustavo Duque
Marrow (MAT) and subcutaneous (SAT) adipose tissues display different metabolic profiles and varying associations with aging, bone density, and fracture risk. Using a non-invasive imaging methodology, we aimed to investigate the associations between MAT, SAT, and visceral fat (VAT) with bone volume, bone remodeling markers, insulin resistance, and circulating inflammatory mediators in a population of older men. In this cross-sectional study, 96 healthy men (mean age 67 ± 5.5) were assessed for anthropometric parameters, body composition, serum biochemistry, and inflammatory panel...
March 26, 2018: Calcified Tissue International
https://www.readbyqxmd.com/read/29575220/lumbosacral-plexus-root-thickening-establishing-normal-root-dimensions-using-magnetic-resonance-neurography
#10
Hernán Chaves, Mariana Bendersky, Romina Goñi, César Gómez, Martín Carnevale, Claudia Cejas
INTRODUCTION: Disorders affecting the lumbosacral plexus (LSP) can alter root diameter. Our aim was to determine normal LSP nerve root dimensions using magnetic resonance neurography (MRN). MATERIALS AND METHODS: Eleven asymptomatic patients (ages: 18-53, mean: 34 years) underwent MRN of the LSP on a 3T scanner with an 8-channel torso-PA coil. IDEAL T2-weighted images were acquired and nerve root dimensions were measured from the second lumbar (L2) to the first sacral (S1) vertebrae on the coronal plane, 5 mm from the dorsal root ganglion (DRG)...
March 25, 2018: Clinical Anatomy
https://www.readbyqxmd.com/read/29572605/inflammatory-bowel-disease-across-the-age-continuum-similarity-and-disparity
#11
Amey Dilip Sonavane, Pratibha Sonawane, Deepak N Amarapurkar
OBJECTIVES: To identify similarities and differences between the pediatric-onset and adult-onset Inflammatory Bowel Disease (IBD) based cohorts and further characterize the pediatric cohort. METHODS: A retrospective analysis of pediatric patients attending the tertiary referral care gastroenterology center from 2004 to 2016 was conducted. All the patients were clinically evaluated, investigated and followed up at the centre. RESULTS: Sixty five patients with pediatric IBD were compared with 216 patients with adult-onset IBD...
March 23, 2018: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29567652/transforaminal-lumbar-puncture-an-alternative-technique-in-patients-with-challenging-access
#12
D R Nascene, C Ozutemiz, H Estby, A M McKinney, J B Rykken
Interlaminar lumbar puncture and cervical puncture may not be ideal in all circumstances. Recently, we have used a transforaminal approach in selected situations. Between May 2016 and December 2017, twenty-six transforaminal lumbar punctures were performed in 9 patients (25 CT-guided, 1 fluoroscopy-guided). Seven had spinal muscular atrophy and were referred for intrathecal nusinersen administration. In 2, CT myelography was performed via transforaminal lumbar puncture. The lumbar posterior elements were completely fused in 8, and there was an overlying abscess in 1...
March 22, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29561550/positive-and-negative-nano-electrospray-mass-spectrometry-of-ruthenated-serum-albumin-supported-by-docking-studies-an-integrated-approach-towards-defining-metallodrug-binding-sites-on-proteins
#13
Marija Nišavić, Goran V Janjić, Amela Hozić, Marijana Petković, Miloš K Milčić, Zoran Vujčić, Mario Cindrić
Binding of three ruthenium(ii) compounds of general formula mer-[Ru(L3)(N-N)X][Y] (where L3 = 4'-chloro-2,2':6',2''-terpyridine (Cl-tpy); N-N = 1,2-diaminoethane (en), 1,2-diaminocyclohexane (dach) or 2,2'-bipyridine (bipy); X = Cl; Y = Cl) to human serum albumin (HSA) has been investigated by nano-LC/nano-ESI MS and docking studies. A bottom-up proteomics approach has been applied for the structural characterization of metallated proteins and the data were analyzed in both the positive and negative ion mode...
March 21, 2018: Metallomics: Integrated Biometal Science
https://www.readbyqxmd.com/read/29559725/the-optimal-anatomic-site-for-a-single-slice-to-estimate-the-total-volume-of-visceral-adipose-tissue-by-using-the-quantitative-computed-tomography-qct-in-chinese-population
#14
X Cheng, Y Zhang, C Wang, W Deng, L Wang, Y Duanmu, K Li, D Yan, L Xu, C Wu, W Shen, W Tian
BACKGROUND/OBJECTIVES: To investigate the relationship between the cross-sectional visceral adipose tissue (VAT) areas at different anatomic sites and the total VAT volume in a healthy Chinese population using quantitative computed tomography (QCT), and to identify the optimal anatomic site for a single slice to estimate the total VAT volume. SUBJECTS/METHODS: A total of 389 healthy Chinese subjects aged 19-63 years underwent lumbar spine QCT scans. The cross-sectional area of total adipose tissue and VAT were measured using the tissue composition module of the software (QCT Pro, Mindways) at each intervertebral disc level from T12 /L1 to L5 /S1 , as well as at the umbilical level...
March 20, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29551678/hemocyanin-of-litopenaeus-vannamei-agglutinates-vibrio-parahaemolyticus-ahpnd-vp-ahpnd-and-neutralizes-its-toxin
#15
Pakpoom Boonchuen, Phattarunda Jaree, Anchalee Tassanakajon, Kunlaya Somboonwiwat
Acute hepatopancreatic necrosis disease, AHPND, caused by a specific strain of Vibrio parahaemolyticus (VPAHPND ), results in great loss of global shrimp production. Despite this, studies on shrimp defense mechanisms protecting against AHPND are few. In this study, suppression subtractive hybridization (SSH) was performed to identify differentially expressed genes from white shrimp Litopenaeus vannamei hepatopancreas upon VPAHPND infection at the early stages: 3 and 6 h post challenge and in the late stage at 48 h post challenge...
March 15, 2018: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/29548956/biomechanical-analysis-of-an-expandable-lumbar-interbody-spacer
#16
Hector Soriano-Baron, Anna G U S Newcomb, Devika Malhotra, Atilio E Palma, Eduardo Martinez-Del-Campo, Neil R Crawford, Nicholas Theodore, Brian P Kelly, Taro Kaibara
OBJECTIVE: Recently developed expandable interbody spacers are widely accepted in spinal surgery; however, the resulting biomechanical effects of their use have not yet been fully studied. We analyzed the biomechanical effects of an expandable polyetheretherketone interbody spacer inserted through a bilateral posterior approach with and without different modalities of posterior augmentation. METHODS: Biomechanical nondestructive flexibility testing was performed in 7 human cadaveric lumbar (L2-L5) specimens followed by axial compressive loading...
March 13, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29548381/formation-of-coal-layered-double-hydroxide-on-the-boehmite-surface-and-its-role-in-tungstate-sorption
#17
Hyuck Hur, Richard J Reeder
Sorption of tungstate on boehmite (γ-AlOOH) is increased by co-sorption with Co2+ over the near-neutral pH range. Batch uptake experiments show up to a 3-fold increase in tungstate uptake over the range WO4 2- =50-1000μmol/L compared to boehmite not treated with Co2+ . Desorption experiments reveal a corresponding decrease in sorption reversibility for tungstate co-sorbed with Co2+ . Reaction of boehmite with Co2+ results in the formation of CoAl layered double hydroxide (LDH), as confirmed by X-ray diffraction and X-ray absorption spectroscopy...
March 2018: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/29548343/double-level-lumbar-spondylolysis-and-spondylolisthesis-a-retrospective-study
#18
Shengtao Zhang, Conglin Ye, Qi Lai, Xiaolong Yu, Xuqiang Liu, Tao Nie, Haibo Zhan, Min Dai, Bin Zhang
BACKGROUND: Lumbar spondylolysis and isthmic spondylolisthesis are common conditions. However, double-level lumbar spondylolysis and spondylolisthesis are rare. We report 24 cases of it along with a review of literature and a briefly description of the clinical and radiological features and integrated management of patients with this condition. METHODS: Of 1700 inpatients diagnosed with lumbar spondylolisthesis at our hospital between January 2008 and September 2015, we selected those with a diagnosis of double-level spondylolisthesis who underwent surgery...
March 16, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29541621/application-of-low-tube-current-with-iterative-model-reconstruction-on-philips-brilliance-ict-elite-fhd-in-the-accuracy-of-spinal-qct-using-a-european-spine-phantom
#19
Yan Wu, Yaojun Jiang, Xueli Han, Mingyue Wang, Jianbo Gao
Background: To investigate the repeatability and accuracy of quantitative CT (QCT) measurement of bone mineral density (BMD) by low-mAs using iterative model reconstruction (IMR) technique based on phantom model. Methods: European spine phantom (ESP) was selected and measured on the Philips Brilliance iCT Elite FHD machine for 10 times. Data were transmitted to the QCT PRO workstation to measure BMD (mg/cm3 ) of the ESP (L1, L2, L3). Scanning method: the voltage of X-ray tube is 120 kV, the electric current of X-ray tube output in five respective groups A-E were: 20, 30, 40, 50 and 60 mAs...
February 2018: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29538033/lumbar-osteophyte-avid-on-68ga-prostate-specific-membrane-antigen-pet-ct
#20
Mads Ryø Jochumsen, Michael Alle Madsen, Lise Gammelgaard, Kirsten Bouchelouche
A 75-year-old man with recently diagnosed high-risk prostate cancer was referred for primary staging with Ga-prostate-specific membrane antigen (PSMA) PET/CT. The scan revealed intense Ga-PSMA uptake in a lumbar osteophyte on the right side of level L2/L3, whereas several other spinal osteophytes showed no Ga-PSMA uptake. MRI findings in the L3 vertebra was consistent with a benign Modic type 1 lesion, but MRI showed no signs of malignancy in the osteophyte with high Ga-PMSA uptake. This case presents an osteophyte as an addition to the list of potential benign pitfalls to be aware of when interpreting Ga-PSMA PET/CT...
March 13, 2018: Clinical Nuclear Medicine
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