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Fernando Chaves, José Garnacho-Montero, José Luis Del Pozo, Emilio Bouza, José Antonio Capdevila, Marina de Cueto, M Ángeles Domínguez, Jaime Esteban, Nuria Fernández-Hidalgo, Marta Fernández Sampedro, Jesús Fortún, María Guembe, Leonardo Lorente, Jose Ramón Paño, Paula Ramírez, Miguel Salavert, Miguel Sánchez, Jordi Vallés
Catheter-related bloodstream infections (CRBSI) constitute an important cause of hospital-acquired infection associated with morbidity, mortality, and cost. The aim of these guidelines is to provide updated recommendations for the diagnosis and management of CRBSI in adults. Prevention of CRBSI is excluded. Experts in the field were designated by the two participating Societies (Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica and the Sociedad Española de Medicina Intensiva, Crítica y Unidades Coronarias)...
February 2018: Enfermedades Infecciosas y Microbiología Clínica
Tales Lyra Oliveira, Návylla Candeia-Medeiros, Polliane M Cavalcante-Araújo, Igor Santana Melo, Elaine Fávaro-Pípi, Luciana Alves Fátima, Antônio Augusto Rocha, Luiz Ricardo Goulart, Ubiratan Fabres Machado, Ruy R Campos, Robinson Sabino-Silva
High glucose concentration in the airway surface liquid (ASL) is an important feature of diabetes that predisposes to respiratory infections. We investigated the role of alveolar epithelial SGLT1 activity on ASL glucose concentration and bacterial proliferation. Non-diabetic and diabetic rats were intranasally treated with saline, isoproterenol (to increase SGLT1 activity) or phlorizin (to decrease SGLT1 activity); 2 hours later, glucose concentration and bacterial proliferation (methicillin-resistant Sthaphylococcus aureus, MRSA and Pseudomonas aeruginosa, P...
February 23, 2016: Scientific Reports
M M Echezarreta-López, T De Miguel, F Quintero, J Pou, M Landin
A laser-spinning technique has been used to produce amorphous, dense and flexible glass nanofibers of two different compositions with potential utility as reinforcement materials in composites, fillers in bone defects or scaffolds (3D structures) for tissue engineering. Morphological and microstructural analyses have been carried out using SEM-EDX, ATR-FTIR and TEM. Bioactivity studies allow the nanofibers with high proportion in SiO2 (S18/12) to be classified as a bioinert glass and the nanofibers with high proportion of calcium (ICIE16) as a bioactive glass...
December 30, 2014: International Journal of Pharmaceutics
Rogério Heládio Lopes Motta, Juliana Cama Ramacciato, Francisco Carlos Groppo, Aline de Barros Nóbrega Dias Pacheco, Thales Rocha de Mattos-Filho
PURPOSE: To verify environmental contamination by collecting microorganisms from dental equipment surfaces before, during and after clinical procedures. METHODS: Sterile swabs were used to collect the samples from dental-chair push buttons, 3-in-1 syringes, X-ray tubes, computer keys, doorknobs, and light handles before (P1), during (P2) and after (P3) clinical procedures, in the undergraduate clinic of the Dental School of Piracicaba, University of Campinas, Brazil...
October 2005: American Journal of Dentistry
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