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https://www.readbyqxmd.com/read/28731207/polyclonal-and-monoclonal-antibodies-for-treating-acute-rejection-episodes-in-kidney-transplant-recipients
#1
REVIEW
Angela C Webster, Sunny Wu, Krishna Tallapragada, Min Young Park, Jeremy R Chapman, Sue J Carr
BACKGROUND: Registry data shows that the incidence of acute rejection has been steadily falling. Approximately 10% to 35% of kidney recipients will undergo treatment for at least one episode of acute rejection within the first post-transplant year. Treatment options include pulsed steroid therapy, the use of an antibody preparation, the alteration of background immunosuppression, or combinations of these options. Over recent years, new treatment strategies have evolved, and in many parts of the world there has been an increase in use of tacrolimus and mycophenolate and a reduction in the use of cyclosporin and azathioprine use as baseline immunosuppression to prevent acute rejection...
July 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28730900/falls-prevention-interventions-for-older-adults-with-low-vision-a-scoping-review-%C3%A3-tude-de-port%C3%A3-e-sur-les-interventions-visant-%C3%A3-pr%C3%A3-venir-les-chutes-chez-les-a%C3%A3-n%C3%A3-s-ayant-une-basse-vision
#2
Sarah E Blaylock, Laura K Vogtle
BACKGROUND: Older adults with low vision are especially vulnerable to falls. There are no comprehensive reviews of fall prevention interventions for older adults with vision loss who live in the community. PURPOSE: The aim of this study was to review the evidence regarding community-based falls prevention interventions that appear inclusive of and/or accessible to individuals with low vision. METHOD: A scoping review was completed using the framework developed by Arksey and O'Malley, and the charted data were analyzed using sums and percentages and qualitative content analysis...
June 2017: Canadian Journal of Occupational Therapy. Revue Canadienne D'ergothérapie
https://www.readbyqxmd.com/read/28730504/changing-trends-in-stomach-cancer-throughout-the-world
#3
REVIEW
Maya Balakrishnan, Rollin George, Ashish Sharma, David Y Graham
PURPOSE OF REVIEW: The paper aims to discuss the global trends in gastric cancer incidence in relation to important factors involved in the pathogenesis of gastric cancer. RECENT FINDINGS: Despite a significant worldwide decline, gastric cancer remains a common cause of cancer death. The decline has been multifactorial and preceded the fall in Helicobacter pylori prevalence. The initial decline was associated with changes in food preservation and availability, especially of fresh fruits and vegetables, followed by a decline in the primary etiologic factor, H...
August 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/28728627/sharing-knowledge-of-falls-prevention-for-people-with-dementia-insights-for-community-care-practice
#4
Claudia Meyer, Sophie Hill, Keith D Hill, Briony Dow
People living with dementia (PLWD) fall more frequently, with more adverse consequences, than general community-dwelling older people; however, falls prevention evidence for PLWD is limited. Increased success of falls prevention strategies for PLWD may rely on tailored interventions to address dementia-specific risk factors. The Australian person-centred care environment highlights the need to better understand sharing of falls prevention knowledge between clients, carers and health professionals. This study aims to examine knowledge of falls prevention for PLWD among community care health professionals (CCHPs) and explore effectiveness of an action-research approach to enhance falls prevention practice...
July 21, 2017: Australian Journal of Primary Health
https://www.readbyqxmd.com/read/28728083/sleep-disturbances-and-risk-of-falls-in-an-old-chinese-population-rugao-longevity-and-ageing-study
#5
Teng Ma, Guoping Shi, Yinsheng Zhu, Yong Wang, Xuefeng Chu, Xiaoyan Jiang, Zuyun Liu, Jian Cai, Hongfei Wang, Li Jin, Zhendong Wang, Xiaofeng Wang
BACKGROUND: To explore the relationship between sleep disturbances and falls in an elderly Chinese population. METHODS: Data from 1726 individuals aged 70-87 years from the Rugao Longevity and Ageing Study were used. The Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep variables. Outcomes were falls ≥1 time per year and falls ≥2 times per year. RESULTS: A total of 22.7% of the participants experienced ≥1 fall, and 9.8% experienced ≥2 falls per year...
July 12, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28725985/diversity-in-fall-characteristics-hampers-effective-prevention-the-precipitants-the-environment-the-fall-and-the-injury
#6
K M Sanders, K Lim, A L Stuart, A Macleod, D Scott, G C Nicholson, L Busija
Falls among the elderly are common and characteristics may differ between injurious and non-injurious falls. Among 887 older Australian women followed for 1.6 years, 32% fell annually. Only 8.5% resulted in fracture and/or hospital admission. The characteristics of those falls are indistinguishable from those not coming to medical attention. INTRODUCTION: The precipitants and environment of all falls occurring among a large cohort of older Caucasian women were categorised by injury status to determine if the characteristics differed between injurious and non-injurious falls...
July 19, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28725327/prevalence-of-undiagnosed-cardiovascular-risk-factors-in-adults-aged-20-40-a-cross-sectional-study-in-2016-in-jeddah-saudi-arabia
#7
Faisal Saed Alharthi, Jamilah Saad Alrahimi, Abdulrahman Ali Alotaibi, Daniah Ahmed Alhamdi, Bashair Mohammed Ibrahim, Yasmina Aymen Badeeb
BACKGROUND: Cardiovascular diseases (CVDs) are the first leading cause of death worldwide. In Saudi Arabia, CVDs are the major killers with a mortality rate of 46%. CVD risk factors are not exclusive to old populations. Thus, the purpose of this study was to approximately find the prevalence of these risk factors, particularly high blood pressure (HBP), high blood glucose (HBG), obesity, and smoking. METHODS: This cross-sectional was conducted in May 2016 and took place in the Ambulatory Care Center of King Abdulaziz Medical City, Jeddah...
June 2017: Cardiology Research
https://www.readbyqxmd.com/read/28725324/cardiorenal-syndrome-role-of-arginine-vasopressin-and-vaptans-in-heart-failure
#8
REVIEW
Poornima Vinod, Vinod Krishnappa, Abigail M Chauvin, Anshika Khare, Rupesh Raina
Heart and kidney failure continued to be of increasing prevalence in today's society, and their comorbidity has synergistic effect on the morbidity and mortality of patients. Cardiorenal syndrome (CRS) is a complex disease with multifactorial pathophysiology. Better understanding of this pathophysiological network is crucial for the successful intervention to prevent advancement of the disease process. One of the major factors in this process is neurohormonal activation, predominantly involving renin-angiotensin-aldosterone system (RAAS) and arginine vasopressin (AVP)...
June 2017: Cardiology Research
https://www.readbyqxmd.com/read/28725160/significance-of-quality-of-care-for-quality-of-life-in-persons-with-dementia-at-risk-of-nursing-home-admission-a-cross-sectional-study
#9
Christina Bökberg, Gerd Ahlström, Staffan Karlsson
BACKGROUND: Quality of life in persons with dementia is, in large part, dependent on the quality of care they receive. Investigating both subjective and objective aspects of quality of care may reveal areas for improvement regarding their care, which information may ultimately enable persons with dementia to remain living in their own homes while maintaining quality of life. The aim of this study was to 1) describe self-reported quality of life in persons with dementia at risk of nursing home admission...
2017: BMC Nursing
https://www.readbyqxmd.com/read/28723840/cervical-spine-evaluation-and-clearance-in-the-intoxicated-patient-a-prospective-western-trauma-association-multi-institutional-trial-and-survey
#10
Matthew J Martin, Lisa D Bush, Kenji Inaba, Saskya Byerly, Martin Schreiber, Kimberly A Peck, Galinos Barmparas, Jay Menaker, Joshua P Hazelton, Raul Coimbra, Martin D Zielinski, Carlos V R Brown, Chad G Ball, Jill R Cherry-Bukowiec, Clay Cothren Burlew, Julie Dunn, C Todd Minshall, Matthew M Carrick, Gina M Berg, Demetrios Demetriades, William Long
INTRODUCTION: Intoxication often prevents clinical clearance of the cervical spine (Csp) after trauma leading to prolonged immobilization even with a normal CT scan. We evaluated the accuracy of CT at detecting clinically significant Csp injury, and surveyed participants on related opinions and practice. METHODS: A prospective multicenter study (2013-2015) at 17 centers. All adult blunt trauma patients underwent structured clinical examination and imaging including a Csp CT, with follow-up thru discharge...
July 19, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28723702/reducing-falls-in-the-inpatient-hospital-setting
#11
Catherine M Melin
AIM: This quality improvement project's objective was to introduce and assess a process change to potentially reduce fall rates on an inpatient medical-surgical unit. METHODS: The Iowa Model of Evidence-Based Practice was used to guide the implementation of this project. This project was piloted over a 3-month period from October to December 2016 on a 38-bed medical-surgical unit at a community-based hospital in the southeastern United States. Prior to the implementation of this quality improvement project, staff received falls education using a modified pre-existing falls prevention protocol, with a focus on increasing the consistency of bed/chair alarm use for patients identified as being at risk for falling...
July 18, 2017: International Journal of Evidence-based Healthcare
https://www.readbyqxmd.com/read/28721959/a-study-of-falls-among-elderly-persons-in-a-rural-area-of-haryana
#12
Aniket Sirohi, Ravneet Kaur, Anil Kumar Goswami, Kalaivani Mani, Baridalyne Nongkynrih, Sanjeev Kumar Gupta
BACKGROUND: Falls are a common, disabling, and frequently fatal health concern among elderly persons. Assessment of the prevalence of falls and associated factors can lead to the identification of corrective measures, which can help in preventing falls and their consequent effects on health and well-being of the elderly. OBJECTIVES: The objective is to determine the prevalence of falls among elderly persons in a rural area and to study the association of falls with sociodemographic variables and selected health conditions...
April 2017: Indian Journal of Public Health
https://www.readbyqxmd.com/read/28721431/depressive-symptoms-falls-and-fear-of-falling-in-old-korean-adults-the-korean-longitudinal-study-on-health-and-aging-klosha
#13
Y Park, N-J Paik, K W Kim, H-C Jang, J-Y Lim
Fall is a common cause of disability and death in old adults, and much research has been focused on identifying risk factors and developing preventive measures. Yet the majority of preceding research has been focused on physical performance. This study aims to evaluate the association between fall and depressive symptoms in community-dwelling elderly. Cross-sectional data of 431 men and 546 women was collected from old Korean adults living in Seongnam, Korea. Geriatric fall assessment was conducted by self-report questionnaires...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/28721028/frailty-in-community-dwelling-older-adults-association-with-adverse-outcomes
#14
Sergio Sánchez-García, Carmen García-Peña, Antoni Salvà, Rosalinda Sánchez-Arenas, Víctor Granados-García, Juan Cuadros-Moreno, Laura Bárbara Velázquez-Olmedo, Ángel Cárdenas-Bahena
BACKGROUND: The study of frailty is important to identify the additional needs of medical long-term care and prevent adverse outcomes in community dwelling older adults. This study aimed to determine the prevalence of frailty and its association with adverse outcomes in community dwelling older adults. METHODS: A cross-sectional study was carried out from April to September 2014. The population sample was 1,252 older adults (≥60 years) who were beneficiaries of the Mexican Institute of Social Security (IMSS) in Mexico City...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28719088/understanding-and-managing-the-risk-of-head-impact-from-in-hospital-falls-a-cross-sectional-analysis-of-data-from-166-public-hospitals
#15
Satyan R Chari, Paul Varghese, Rebecca A R Bell, Kate Smith, Terry P Haines
BACKGROUND: Falls are a leading cause of preventable harm in the hospitalized elderly, and head impacts (HIs) can be a precursor to serious injury. The aim of this study was to examine if the risk of fall-related HI can be explained by incident characteristics. METHODS: All reported falls across public hospital facilities in the state of Queensland, Australia, over a 2-year period were analyzed using univariate and multiple logistic regression. RESULTS: In all, 650 instances of HI were reported across 24 218 falls...
July 2017: Journal of Healthcare Risk Management: the Journal of the American Society for Healthcare Risk Management
https://www.readbyqxmd.com/read/28718704/a-study-of-sports-related-orbital-fractures-in-singapore
#16
Jing Zhan Lock, Raghuraj Hegde, Stephanie Young, Thiam Chye Lim, Shantha Amrith, Gangadhara Sundar
With an increased popularity of sport and active living worldwide, our study aims to explore the incidence and features of sports-related orbital fractures in Singapore. 1421 computer tomography (CT) imaging scans of the face and orbits done at the National University Hospital over a 24-month period from January 2013 and December 2014 were reviewed retrospectively for orbital fractures. We identified 483 orbital fractures of which sports injury was the fourth most common etiology (n = 65; 13.5%) after road traffic accident (n = 131; 27...
July 18, 2017: Orbit
https://www.readbyqxmd.com/read/28718303/benign-paroxysmal-positional-vertigo-management-and-its-impact-on-falls
#17
Kiran Jumani, Jason Powell
INTRODUCTION: Benign paroxysmal positional vertigo (BPPV) is the most common cause of dizziness in the elderly. This has been identified as a risk factor in falls. Falls are the leading cause of disability and the leading cause of death from injury among people over 75 in the UK. METHODS: We assessed the effect of BPPV treatment on falls in an elderly population by retrospectively reviewing one unit's experience of BPPV management over an 8-year period from June 2008 to June 2016...
August 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28718008/the-effect-of-vitamin%C3%A2-d-and-calcium-supplementation-on-falls-in-older-adults-a%C3%A2-systematic-review-and-meta-analysis
#18
Haiting Wu, Qingjiang Pang
OBJECTIVES: A number of studies have hypothesized that vitamin D is a potential factor in the prevention of falls in the elderly; however, the effect of vitamin D is still inconsistent and not quantitative. We conducted this meta-analysis to assess the effect of vitamin D on falls among elderly individuals. METHODS: The PubMed and Cochrane Library databases were searched from the earliest possible year up to December 2016. Two authors working independently reviewed the trials, and odds ratios (ORs) were calculated using a fixed-effect or random-effect model by Review Manager 5...
July 17, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/28717984/falls-in-older-people-comparing-older-and-younger-fallers-in-a-developing-country
#19
R R Yogi, I Sammy, J F Paul, P Nunes, P Robertson, V Ramcharitar Maharaj
PURPOSE: While falls are common in older people, causing significant mortality and morbidity, this phenomenon has not been extensively studied in the Caribbean. This study aimed to compare falls in older and younger people in this setting. METHODS: We conducted a prospective observational study of older trauma patients in Trinidad, comparing older and younger patients sustaining falls. RESULTS: 1432 adult trauma patients were included (1141 aged 18-64 years and 291 aged 65 years and older)...
July 17, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/28717890/application-of-phototherapy-for-the-healing-of-the-navels-of-neonatal-dairy-calves
#20
Ana Lúcia Borges de Souza Faria, Luis Augusto Lupato Conrado, Luiz Sergio Vanzela, Antonio Balbin Villaverde, Egberto Munin
The present work evaluated the effects of LED light irradiation on the healing of the navels of neonatal dairy calves. Fifty-seven neonatal calves were divided into two groups. Animals had their umbilical stumps immersed in 10% iodine tincture for 60 s, and this process was repeated every 24 h for three consecutive days. The 29 animals in the first group did not receive LED therapy. The 28 animals in the second group received LED light irradiation at 640 nm with 300 mW power, 46.8 J/cm(2) energy density, 60 s irradiation time, and 0...
July 17, 2017: Lasers in Medical Science
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