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https://www.readbyqxmd.com/read/29168514/specific-protein-supplementation-using-soya-casein-or-whey-differentially-affects-regional-gut-growth-and-luminal-growth-factor-bioactivity-in-rats-implications-for-the-treatment-of-gut-injury-and-stimulating-repair
#1
Tania Marchbank, Nikki Mandir, Denis Calnan, Robert A Goodlad, Theo Podas, Raymond J Playford
Modulation of regional growth within specific segments of the bowel may have clinical value for several gastrointestinal conditions. We therefore examined the effects of different dietary protein sources on regional gut growth and luminal growth factor bioactivity as potential therapies. Rats were fed for 14 days on isonitrogenous and isocaloric diets comprising elemental diet (ED) alone (which is known to cause gut atrophy), ED supplemented with casein or whey or a soya protein-rich feed. Effects on regional gut growth and intraluminal growth factor activity were then determined...
November 23, 2017: Food & Function
https://www.readbyqxmd.com/read/29168434/changes-in-knee-shape-and-geometry-resulting-from-total-knee-arthroplasty
#2
Mohsen Akbari Shandiz, Paul Boulos, Stefan Karl Saevarsson, Heiko Ramm, Chun Kit Jack Fu, Stephen Miller, Stefan Zachow, Carolyn Anglin
Changes in knee shape and geometry resulting from total knee arthroplasty can affect patients in numerous important ways: pain, function, stability, range of motion, and kinematics. Quantitative data concerning these changes have not been previously available, to our knowledge, yet are essential to understand individual experiences of total knee arthroplasty and thereby improve outcomes for all patients. The limiting factor has been the challenge of accurately measuring these changes. Our study objective was to develop a conceptual framework and analysis method to investigate changes in knee shape and geometry, and prospectively apply it to a sample total knee arthroplasty population...
November 1, 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/29168231/a-newly-hybrid-anchoring-balloon-for-direct-peroral-cholangioscopy-using-an-ultraslim-upper-endoscope
#3
Jian Li, Shao-Ju Guo, Jing-Chao Zhang, Hong-Yan Wang, Kai Li, She-Hui Niu
OBJECTIVES: Large impacted or residual invisible common bile duct (CBD) stones after mechanical lithotripsy are challenging. We aimed to evaluate the feasibility and success rate of a new hybrid anchoring balloon-guided direct peroral cholangioscopy (POC) for these conditions, using an ultraslim endoscope. METHODS: Sixty-five patients with large or residual invisible CBD stones for direct POC from July 2012 to July 2016 were identified, including 6 cases in whom an additional interventional procedure was required...
November 23, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29167943/penetrating-crohn-disease-does-it-occur-in-the-absence-of-stricturing-disease
#4
Emily S Orscheln, Jonathan R Dillman, Alexander J Towbin, Lee A Denson, Andrew T Trout
PURPOSE: To establish the relationship between penetrating complications and bowel luminal narrowing/stricturing disease in pediatric Crohn disease (CD). MATERIALS AND METHODS: This retrospective study was IRB-approved and HIPAA compliant with waiver of informed consent. CT and MRI examinations describing intra-abdominal penetrating complications in CD patients ≤ 18 years old between January 1, 2009 and March 31, 2016 were reviewed to document: type of complication, affected bowel segment, minimum bowel luminal diameter, maximum upstream diameter, location of penetrating complication relative to luminal narrowing, length of narrowed bowel segment, and the presence of active bowel wall inflammation...
November 22, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29167831/laparoscopic-distal-gastrectomy-with-d2-lymphadenectomy-followed-by-intracorporeal-gastroduodenostomy-for-advanced-gastric-cancer-technical-guide-and-tips
#5
REVIEW
Sang-Woong Lee, Masaru Kawai, Keitaro Tashiro, George Bouras, Satoshi Kawashima, Ryo Tanaka, Eiji Nomura, Kazuhisa Uchiyama
In 1994, Kitano and colleagues first reported laparoscopy-assisted Billroth I gastrectomy. Since then, laparoscopic gastrectomy (LG) has been associated with earlier patient recovery compared with open surgery, and has gained increasing international acceptance. Japan Society of Endoscopic Surgery biennial surveys confirm the increasing use of laparoscopic procedures for treatment of gastric cancer in Japan. Its thirteenth national survey indicates that of 31,264 patients treated at Japanese institutions in 2015, approximately 9,500 (30...
2017: Translational Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29167705/comparative-analysis-of-impacted-upper-canines-panoramic-radiograph-vs-cone-beam-computed-tomography
#6
Catarina-Luís-Vicente-Rodrigues Pico, Francisco-José-Fernandes do Vale, Francisco-José-Santiago-Fernandes-Amado Caramelo, Ana Corte-Real, Sónia-Margarida-Alves Pereira
Background: The use of CBCT exam in the study of IMC is not new. However, it's still not known in what specific aspects CBCT exam shows a better result than then conventional exams. The aim of this study was to compare and conclude in what way the opinion regarding upper canine impaction differed when observing a panoramic image compared to the observation of a set of CBCT reconstructions. Material and Methods: Twenty patients (10 males and 10 females) with a total of 28 impacted maxillary canines were identified from the database of the Department of Dentistry, Faculty of Medicine, University of Coimbra...
October 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29167019/reassessing-the-utility-of-ct-angiograms-in-penetrating-injuries-to-the-extremities
#7
Lori A Gurien, Andrew J Kerwin, Brian K Yorkgitis, John Renkosik, J Christian Allmon, Joseph H Habib, James W Dennis
BACKGROUND: Computed tomography angiography has become routine in the management of penetrating trauma to the extremity. Our objective was to evaluate the efficacy of physical examination findings compared with computed tomography angiography for detection of clinically significant vascular injuries associated with penetrating trauma to the extremity. METHODS: This was a retrospective chart review of patients presenting to a single level 1 trauma center from January 2013-June 2016...
November 20, 2017: Surgery
https://www.readbyqxmd.com/read/29166684/-implantation-of-a-modular-distal-femoral-replacement-with-compressive-osseointegration-as-a-salvage-procedure-in-a-complex-femoral-posttraumatic-setting
#8
Anna Janine Schreiner, Peter Marten de Zwart, Christian Arnscheidt, Ulrich Stöckle, Björn Gunnar Ochs
Background Large bone defects and losses play a crucial role in both tumour surgery and in complex primary and revision total knee replacement. The established options of cemented or uncemented long intramedullary stems are limited by large bone defects and are at risk from relatively high exposure to aseptic loosening. There is no general valid agreement on implant fixation of the distal femur. A further option is the cementless fixation method with compressive osseointegration, based on the so-called Wolff law of bone remodelling...
November 22, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/29165862/an-assessment-of-an-australasian-pathway-for-the-introduction-of-transanal-total-mesorectal-excision-tatme
#9
Sarah C Abbott, Andrew R L Stevenson, Stephen W Bell, David Clark, Arend Merrie, Julian Hayes, Shanthan Ganesh, Alexander G Heriot, Satish K Warrier
AIM: To evaluate the use of a pathway for the introduction of transanal total mesorectal excision (taTME) into Australia and New Zealand. METHOD: A pathway for surgeons with an appropriate level of specialist training and baseline skillset was initiated amongst colorectal surgeons; it includes an intensive course, a series of proctored cases and ongoing contribution to audit. Data were collected for patients who had taTME, for benign and malignant conditions, undertaken by the initial adopters of the technique...
November 22, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29164165/platelet-rich-plasma-for-primary-treatment-of-partial-ulnar-collateral-ligament-tears-mri-correlation-with-results
#10
J Banks Deal, Ed Smith, Wendell Heard, Michael J O'Brien, Felix H Savoie
Background: Jobe revolutionized the treatment of medial ulnar collateral ligament (MUCL) tears with his reconstruction technique. However, not all MUCL injuries require operative management; Rettig showed that 42% of MUCL injuries respond to conservative management. This was improved by Podesta, who showed that augmentation of nonoperative management with platelet-rich plasma (PRP) and magnetic resonance imaging (MRI) for detecting partial MUCL tears resulted in significantly higher success rates...
November 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29163968/brushing-the-distal-biliary-stricture-in-the-surrounding-of-the-papilla-increased-the-risk-of-post-endoscopic-retrograde-cholangiopancreatography-pancreatitis-a-retrospective-study-using-propensity-score-analysis
#11
Kunihiro Kato, Satoshi Sugimori, Yuki Kakiya, Hirotsugu Maruyama, Shusei Fukunaga, Yasuaki Nagami, Masatsugu Shiba, Tetsuya Tanigawa, Toshio Watanabe, Yasuhiro Fujiwara
Background and aims: Brushing cytology is useful for diagnosing biliary strictures. With regard to biliary stricture brushing at the distal common bile duct in the surrounding of the papilla, the risk of post-endoscopic retrograde cholangiopancreatography pancreatitis is unknown. Our study aimed to evaluate the risk of post-endoscopic retrograde cholangiopancreatography pancreatitis by using this procedure. Methods: A total of 150 endoscopic retrograde cholangiopancreatography-naïve patients undergoing endoscopic retrograde cholangiopancreatography including biliary stricture brushing were retrospectively analyzed...
November 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29163576/quantitative-trait-loci-and-maternal-effects-affecting-the-strong-grain-dormancy-of-wild-barley-hordeum-vulgare-ssp-spontaneum
#12
Shingo Nakamura, Mohammad Pourkheirandish, Hiromi Morishige, Mohammad Sameri, Kazuhiro Sato, Takao Komatsuda
Wild barley (Hordeum vulgare ssp. spontaneum) has strong grain dormancy, a trait that may enhance its survival in non-cultivated environments; by contrast, cultivated barley (Hordeum vulgare ssp. vulgare) has weaker dormancy, allowing uniform germination in cultivation. Malting barley cultivars have been bred for especially weak dormancy to optimize their use in malt production. Here, we analyzed the genetic mechanism of this difference in seed dormancy, using recombinant inbred lines (RILs) derived from a cross between the wild barley accession 'H602' and the malting barley cultivar 'Kanto Nakate Gold (KNG)'...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29163054/motor-deficits-and-cerebellar-atrophy-in-elovl5-knock-out-mice
#13
Eriola Hoxha, Rebecca M C Gabriele, Ilaria Balbo, Francesco Ravera, Linda Masante, Vanessa Zambelli, Cristian Albergo, Nico Mitro, Donatella Caruso, Eleonora Di Gregorio, Alfredo Brusco, Barbara Borroni, Filippo Tempia
Spino-Cerebellar-Ataxia type 38 (SCA38) is caused by missense mutations in the very long chain fatty acid elongase 5 gene, ELOVL5. The main clinical findings in this disease are ataxia, hyposmia and cerebellar atrophy. Mice in which Elovl5 has been knocked out represent a model of the loss of function hypothesis of SCA38. In agreement with this hypothesis, Elovl5 knock out mice reproduced the main symptoms of patients, motor deficits at the beam balance test and hyposmia. The cerebellar cortex of Elovl5 knock out mice showed a reduction of thickness of the molecular layer, already detectable at 6 months of age, confirmed at 12 and 18 months...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29162306/osteosynthesis-of-ao-ota-13-c3-distal-humeral-fractures-in-patients-older-than-70-years
#14
Steven F Shannon, Eric R Wagner, Matthew T Houdek, Daniel Mascarenhas, Raymond A Pensy, Walter A Eglseder
OBJECTIVE: The purpose of this retrospective case series was to examine the AO Foundation and Orthopaedic Trauma Association (AO/OTA) 13-C3 distal humeral fractures treated with open reduction-internal fixation (ORIF) in patients older than 70 years. METHODS: During an 8-year period, 21 patients older than 70 years with AO/OTA 13-C3 distal humeral fractures were treated with ORIF performed by 2 senior upper extremity traumatologists. There were 16 patients with >1 year of follow-up, with a mean age of 78 (70-84) years...
November 18, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29157109/comparison-of-patellar-tracking-according-to-different-angles-of-external-rotation-of-femoral-component-in-varus-knee-of-asians
#15
Jai Hyung Park, Seong-Il Bin, Jong-Min Kim, Bum-Sik Lee, Chang-Rack Lee, Jong-Min Kim, Yongun Cho
PURPOSE: Racial difference in the femoral geometry may exist. Asian femurs may be more externally rotated. If anatomical differences in distal femur had existed between Caucasians and Asians, the group with 5° external rotation of the femoral component should have shown better results than the group with 3° external rotation of the femoral component have. METHODS: 598 patients underwent total knee arthroplasty in our institution, among whom 83 patients (115 knees) who had postoperative computed tomography (CT) were studied retrospectively...
September 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/29154969/adults-with-cystic-fibrosis-have-deficits-in-bone-structure-and-strength-at-the-distal-tibia-despite-similar-size-and-measuring-standard-and-relative-sites
#16
Kyle K Nishiyama, Sanchita Agarwal, Anna Kepley, Fernando Rosete, Yizhong Hu, X Edward Guo, Claire L Keating, Emily A DiMango, Elizabeth Shane
Individuals with cystic fibrosis (CF) have lower bone mineral density (BMD) by DXA and are at higher risk of fracture than healthy controls. However, the 2-dimensional measurement of areal BMD (aBMD) provided by DXA is influenced by bone size and the true extent of the bone deficit is unclear. Our objective was to use high-resolution peripheral quantitative computed tomography (HR-pQCT) and individual trabecula segmentation (ITS) analysis to compare volumetric BMD (vBMD), microarchitecture and estimated strength at the distal radius and tibia in 26 young adults with CF and 26 controls matched for age, gender, and race...
November 14, 2017: Bone
https://www.readbyqxmd.com/read/29151690/region-dependent-effects-of-diabetes-and-insulin-replacement-on-neuronal-nitric-oxide-synthase-and-heme-oxygenase-immunoreactive-submucous-neurons
#17
Nikolett Bódi, Zita Szalai, Lalitha Chandrakumar, Mária Bagyánszki
AIM: To investigate the intestinal segment-specific effects of diabetes and insulin replacement on the density of different subpopulations of submucous neurons. METHODS: Ten weeks after the onset of type 1 diabetes samples were taken from the duodenum, ileum and colon of streptozotocin-induce diabetic, insulin-treated diabetic and sex- and age-matched control rats. Whole-mount preparations of submucous plexus were prepared from the different gut segments for quantitative fluorescent immunohistochemistry...
November 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29149965/comparision-of-ureteral-stent-colonization-between-deceased-and-live-donor-renal-transplant-recipients
#18
M Sarier, D Seyman, S Tekin, I Duman, B Uygun, M Demir, E Kukul, A H Yavuz
BACKGROUND: The use of a ureteral stent can cause a urinary tract infection (UTI), although it reduces urologic complications. UTIs are associated with a higher rate of ureteral stent colonization (USC). The aim of this study was to compare USC in living and deceased donor renal transplant recipients. MATERIAL AND METHODS: We conducted a prospective study of 48 patients who underwent renal transplantation between January and December 2016. The stents were removed aseptically, the inner surface of proximal and distal ends of stents were irrigated with liquid culture medium, and then they were vortexed for bacteriological investigation...
November 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/29148142/outcomes-of-primary-percutaneous-coronary-intervention-in-acute-myocardial-infarction-due-to-unprotected-left-main-thrombosis-the-asia-pacific-left-main-st-elevation-registry-aster
#19
Jonathan Yap, Gagan D Singh, Jung-Sun Kim, Krishan Soni, Kelvin Chua, Alvin Neo, Choong Hou Koh, Ehrin J Armstrong, Stephen W Waldo, Kendrick A Shunk, Reginald I Low, Myeong-Ki Hong, Yangsoo Jang, Khung Keong Yeo
INTRODUCTION: Prior studies of ULM STEMI have been confined to small cohorts. Recent registry data with larger patient cohorts have shown contrasting results. We aim to study the outcomes of patients with unprotected left main (ULM) ST-elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (PCI). METHODS: The Asia-pacific left main ST-Elevation Registry (ASTER) is a multicenter retrospective registry involving 4 sites in Singapore, South Korea, and the United States...
November 16, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29148001/an-arterioarterial-prosthetic-graft-as-an-alternative-option-for-haemodialysis-access-a-systematic-review
#20
Matthew J Grima, Bianca Vriens, Peter J Holt, Eric Chemla
INTRODUCTION: All arteriovenous fistula/grafts options should be exhausted before haemodialysis is carried out via central venous catheters (CVC). CVCs carry high morbidity and mortality risks and in some patients, the central veins could be exhausted. In these patients, an arterioarterial prosthetic loop (AAPL) or straight graft can be the only option for haemodialysis. A systematic review was thus carried out to look at the use of arterioarterial graft for haemodialysis, with regards to dialysis adequacy, complications, and patency rates...
November 10, 2017: Journal of Vascular Access
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