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https://www.readbyqxmd.com/read/28795888/effective-wound-bed-preparation-using-maggot-debridement-therapy-for-patients-with-critical-limb-ischaemia
#1
A Nishijima, M Gosho, R Yoshida, S Yanagibayashi, M Takikawa, J Nishijima, M Sekido, N Yamamoto
OBJECTIVE: Patients with critical limb ischaemia (CLI) lack sufficient blood flow in to the limb, which leads to difficulties in the normal wound healing process. Therefore, maggot debridement therapy (MDT) has not generally been recommended for CLI patients. We evaluated the effectiveness of wound bed preparation by MDT in CLI patients who had undergone mid-foot amputation. METHODS: Patients who underwent mid-foot amputation after angioplasty between April 2014 and October 2016 were retrospectively investigated by classifying them into an MDT group or a conventional treatment group...
August 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28781904/second-report-of-accidental-intestinal-myiasis-due-to-eristalis-tenax-diptera-syrphidae-in-iran-2015
#2
Ramezani Awal Riabi Hamed, Ramezani Awal Riabi Hamid, Naghizade Hamid
We have described a new case of accidental intestinal myiasis that had occurred due to Eristalis tenax in Iran. A 4-year-old girl living in rural area near Bajestan city located in the south of Khorasan Razavi province visited the hospital lab with complaints of one live larva in feces and did not have other symptoms, except anal itching. This case had a history of consuming subterranean village water and did not have a history of traveling outside the city or contact with other patients. Conclusion. Based on the morphology characteristic, the larva was identified as "rat-tailed maggot" or larvae fly E...
2017: Case Reports in Emergency Medicine
https://www.readbyqxmd.com/read/28726434/-salvation-of-the-diabetic-foot-through-a-comprehensive-individualized-treatment-of-the-patient-with-type-2-diabetes-case-study
#3
Ivana Flanderová
This is a case of men with type 2 diabetes mellitus and diabetic foot. The patient was in danger of limb amputation. After improvement of diabetes, hypertension and dyslipidemia therapies a comprehensive treatment of diabetic foot including angioplasty, antibiotics and local maggot therapy was used for diabetic foot management. Therapy result was very satisfying for the patient. Despite of amputation of the 2nd digit due to advanced gangrene, the whole foot function was saved.Key words: diabetes foot - maggot therapies - type 2 diabetes mellitus...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/28684791/development-of-insect-life-tables-comparison-of-two-demographic-methods-of-delia-antiqua-diptera-anthomyiidae-on-different-hosts
#4
Shuoying Ning, Wenchao Zhang, Yan Sun, Jinian Feng
In this study, we first construct an age-stage, two-sex life table for onion maggot, Delia antiqua, grown on three host plants: onion, scallion, and garlic. We found that onion is the optimal host for this species and populations grown on onion have maximum fecundity, longest adult longevity and reproduction period, and the shortest immature developmental time. In contrast, the fecundity on other hosts was lower, particularly on garlic, but these crops can also serve as important secondary hosts for this pest...
July 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28637365/insight-into-the-c-f-bond-mechanism-of-molecular-analogs-for-antibacterial-drug-design
#5
Junna Liu, Biyu Lv, Huaqing Liu, Xin Li, Weiping Yin
The activities of biological molecules usually rely on both of intra-molecular and intermolecular interactions between their function groups. These interactions include interonic attraction theory, Van der Waal's forces and the function of geometry on the individual molecules, whether they are naturally or synthetic. The purpose of this study was to evaluate the antibacterial activity of C-F bond compound using combination of experiments verification and theoretical calculation. We target on the insect natural products from the maggots of Chrysomyis megacephala Fabricius...
June 21, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28599051/maggot-therapy-for-wound-care-in-austere-environments
#6
Ronald A Sherman, Michael R Hetzler
The past 25 years have seen an increase in use of maggot therapy for wound care. Maggot therapy is very effective in wound debridement; it is simple to apply and requires very little in the way of resources, costs, or skilled personnel. These characteristics make it well suited for use in austere environments. The use of medical-grade maggots makes maggot therapy nearly risk free, but medical grade maggots may not always be available, especially in the wilderness or in resource-limited communities. By understanding myiasis and fly biology, it should be possible even for the nonentomologist to obtain maggots from the wild and apply them therapeutically, with minimal risks...
2017: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
https://www.readbyqxmd.com/read/28570137/benefits-of-maggot-debridement-therapy-on-leg-ulcers-a-literature-review
#7
Genevieve Abela
Maggot debridement therapy (MDT) is an effective method for debriding wounds such as leg ulcers, supporting the concept of wound bed preparation ( Dumville et al, 2009 ; Soares et al, 2009 ; Mudge et al, 2014 ). New evidence is emerging to suggest that maggots might contribute to wound healing in other ways. For example, the reduction of biofilms and disinfection of wounds ( Van Der Plas et al, 2008 ; Brown et al, 2012 ; Pritchard and Brown, 2015 ) plus regulation of protease levels ( Chambers et al, 2003 ; Van Der Plas et al, 2009a ; Van Der Plas et al, 2009b )...
June 2, 2017: British Journal of Community Nursing
https://www.readbyqxmd.com/read/28567433/maggot-debridement-therapy-for-a-patient-with-critical-limb-ischaemia-and-severe-cardiac-dysfunction-possibility-of-limb-salvage
#8
Akio Nishijima, Naoto Yamamoto, Ryuichi Yoshida, Koji Hozawa, Satoshi Yanagibayashi, Megumi Takikawa, Rie Hayasaka, Junko Nishijima, Tadasu Okada, Mitsuru Sekido
Ischaemic skin ulcer occurred on the foot of a 73-year-old man who had a history of fulminant myocarditis with severe cardiac dysfunction. We attempted wound bed preparation by maggot debridement therapy and salvaged his limb. It can be one of the adjuvant treatment strategies for critical limb ischaemia.
2017: Case Reports in Plastic Surgery & Hand Surgery
https://www.readbyqxmd.com/read/28550155/maggots-in-the-management-of-ulcer-care
#9
Shawnee Munro, Abubakar Hadid, Muhammad Javaid Hameed Rahmani
No abstract text is available yet for this article.
May 26, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28469564/pavlovian-conditioning-of-larval-drosophila-an-illustrated-multilingual-hands-on-manual-for-odor-taste-associative-learning-in-maggots
#10
Birgit Michels, Timo Saumweber, Roland Biernacki, Jeanette Thum, Rupert D V Glasgow, Michael Schleyer, Yi-Chun Chen, Claire Eschbach, Reinhard F Stocker, Naoko Toshima, Teiichi Tanimura, Matthieu Louis, Gonzalo Arias-Gil, Manuela Marescotti, Fabio Benfenati, Bertram Gerber
Larval Drosophila offer a study case for behavioral neurogenetics that is simple enough to be experimentally tractable, yet complex enough to be worth the effort. We provide a detailed, hands-on manual for Pavlovian odor-reward learning in these animals. Given the versatility of Drosophila for genetic analyses, combined with the evolutionarily shared genetic heritage with humans, the paradigm has utility not only in behavioral neurogenetics and experimental psychology, but for translational biomedicine as well...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28423428/aggregation-behavior-and-a-putative-aggregation-pheromone-in-sugar-beet-root-maggot-flies-diptera-ulidiidae
#11
Erik J Wenninger, Susan Y Emmert, Kelly Tindall, Hongjian Ding, Mark A Boetel, D Rajabaskar, Sanford D Eigenbrode
Male-biased aggregations of sugar beet root maggot, Tetanops myopaeformis (Röder) (Diptera: Ulidiidae), flies were observed on utility poles near sugar beet (Beta vulgaris L. [Chenopodiaceae]) fields in southern Idaho; this contrasts with the approximately equal sex ratio typically observed within fields. Peak observation of mating pairs coincided with peak diurnal abundance of flies. Volatiles released by individual male and female flies were sampled from 08:00 to 24:00 hours in the laboratory using solid-phase microextraction and analyzed using gas chromatography/mass spectrometry (GC/MS)...
January 1, 2017: Journal of Insect Science
https://www.readbyqxmd.com/read/28402593/a-new-method-for-the-production-of-sterile-colonies-of-lucilia-sericata
#12
N E Gasz, M L Harvey
Maggot debridement therapy (MDT) refers to the use of blowfly larvae to clean or debride an infected wound. Most commonly, larvae of Lucilia sericata (Meigen) (Diptera: Calliphoridae) are used, and are sterilized prior to use to ensure no further bacterial infections are introduced during treatment. Current methods sterilize eggs from laboratory-reared blowfly colonies, after which sterile early second instar maggots can be provided to hospitals for use in treatment. Maggots not required for treatment are used for colony regeneration, in which sterility is not maintained...
September 2017: Medical and Veterinary Entomology
https://www.readbyqxmd.com/read/28384914/orbital-myiasis-with-scalp-pediculosis-and-buccal-abscess-an-uncommon-presentation
#13
Nidhi Kaeley, Rajeev Mohan Kaushik, Richa Rajput, Renu Dhasmana, Anurag Bhargava
We present a case of severe orbital myiasis caused by Osteris ovis, also known as sheep nasal botfly which is an uncommon manifestation of maggot infestation. Our patient was successfully treated with oral as well as topical ivermectin. The experience of ivermectin as an anti-parasitic agent in the treatment of orbital myiasis, although a known entity, is still limited among medical professionals including ophthalmologists. Thus, we would like to highlight the role of oral ivermectin as an anti-parasitic agent in the treatment of orbital myiasis facilitating the removal of maggots; thus, precluding the need for exploratory surgery...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28374542/to-eat-or-get-heat-behavioral-trade-offs-between-thermoregulation-and-feeding-in-gregarious-necrophagous-larvae
#14
Jana Podhorna, Cindy Aubernon, Marie Borkovcova, Julien Boulay, Valery Hedouin, Damien Charabidze
The thermoregulation behavior of Lucilia sericata larvae (Diptera: Calliphoridae), a necrophagous species that feeds on vertebrate cadavers, was investigated. These larvae require high heat incomes to develop, and can elevate temperatures by forming large aggregates. We hypothesized that L. sericata larvae should continue to feed at temperatures up to 38°C, which can be reached inside larval masses. Thermal regulation behavior such as movement between a hot food spot and colder areas was also postulated. The hypotheses were tested by tracking for 1h the activity of single, starved third instar larvae in a Petri dish containing one food spot (FS) that was heated to a constant temperature of 25°C, 34°C or 38°C with an ambient temperature of 25°C...
April 4, 2017: Insect Science
https://www.readbyqxmd.com/read/28361272/sterilization-of-blow-fly-eggs-chrysomya-megacephala-and-lucilia-cuprina-diptera-calliphoridae-for-maggot-debridement-therapy-application
#15
Kwankamol Limsopatham, Phadungkiat Khamnoi, Kabkaew L Sukontason, Dheerawan Boonyawan, Tarinee Chaiwong, Kom Sukontason
Maggot debridement therapy (MDT) is an application of sterile laboratory-reared blow fly larvae to remove necrotic tissue and disinfect wounds for medical conditions. For effective application, the blow fly larvae used in the wound treatment are required to be in aseptic condition. Here, we report the results of a detailed assessment of bacteria and fungi isolated from the eggs of two blow fly species, Chrysomya megacephala (F.) and Lucilia cuprina (Wiedemann) before and after sterilization by disinfectants Chlorhex-C, povidone-iodine, and sodium hypochlorite...
May 2017: Parasitology Research
https://www.readbyqxmd.com/read/28348762/a-case-of-ignatzschineria-bacteraemia-in-an-unconscious-man-from-the-netherlands
#16
Edou Heddema, Frank Janssen, Harro van Westreenen
INTRODUCTION: Ignatzschineria species were previously known as Schineria species and are well known inhabitants of the larvae of the parasitic fly Wohlfahrtia magnifica. CASE PRESENTATION: We report a case of Ignatzschineria species bacteraemia in a Dutch patient with a wound infested with maggots. CONCLUSION: In the past, these bacteria have been isolated from Wohlfahrtia magnifica, a fly not indigenous to The Netherlands. Other fly larvae such as the blowfly larvae probably infested the wound and harboured this Ignatzschineria strain which subsequently caused this bacteraemia...
June 2016: JMM Case Reports
https://www.readbyqxmd.com/read/28278280/natural-antimicrobial-peptide-complexes-in-the-fighting-of-antibiotic-resistant-biofilms-calliphora-vicina-medicinal-maggots
#17
Natalia Gordya, Andrey Yakovlev, Anastasia Kruglikova, Dmitry Tulin, Evdokia Potolitsina, Tatyana Suborova, Domenico Bordo, Camillo Rosano, Sergey Chernysh
Biofilms, sedimented microbial communities embedded in a biopolymer matrix cause vast majority of human bacterial infections and many severe complications such as chronic inflammatory diseases and cancer. Biofilms' resistance to the host immunity and antibiotics makes this kind of infection particularly intractable. Antimicrobial peptides (AMPs) are a ubiquitous facet of innate immunity in animals. However, AMPs activity was studied mainly on planktonic bacteria and little is known about their effects on biofilms...
2017: PloS One
https://www.readbyqxmd.com/read/28277993/maggot-therapy-for-wound-care-in-iran-a-case-series-of-the-first-28-patients
#18
A Mirabzadeh, M J Ladani, B Imani, S A B Rosen, R A Sherman
OBJECTIVE: The need for improved wound care is receiving considerable attention in the Islamic Republic of Iran. Beginning in 2003, maggot therapy (MT) became part of Iran's effort to advance its wound care technology. The first cohort of patients treated with MT was analysed to evaluate the use of this treatment. METHOD: Patients treated with MT at three hospitals in Tehran were analysed retrospectively. Primary outcomes were time to wound debridement and time to wound healing...
March 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28261793/a-case-of-insect-colonization-before-the-death
#19
Stefano Vanin, Manuela Bonizzoli, Maria Luisa Migliaccio, Laura Tadini Buoninsegni, Valentina Bugelli, Vilma Pinchi, Martina Focardi
Forensic entomology is a branch of forensic science in which insects are used as evidence in legal investigations relating to humans, domestic animals and wildlife. One of the theoretical pillars on which the discipline is based concerns the fact that flies colonize a body after death. However in cases of myiasis, maggots are present before death, with consequences in the correct estimation of the minimum postmortem interval (mPMI). We report here the case of a woman, largely colonized by fly larvae, who has lain alive in her garden for four days prior to being rescued...
March 6, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28235562/urate-oxidase-produced-by-lucilia-sericata-medical-maggots-is-localized-in-malpighian-tubes-and-facilitates-allantoin-production
#20
Andre Baumann, Marisa Skaljac, Rüdiger Lehmann, Andreas Vilcinskas, Zdenӗk Franta
Lucilia sericata maggots are the only species currently approved for maggot debridement therapy (MDT), an alternative treatment for chronic and recalcitrant wounds. Maggots promote wound debridement, disinfection and healing by producing a complex mixture of proteins, peptides and low-molecular-weight compounds in their secretions and excretions, but the individual components are not well characterized at the molecular level. Here we investigated the purine catabolism pathway in L. sericata, focusing on the production of allantoin by Urate Oxidase (UO), which is thought to promote wound healing...
February 22, 2017: Insect Biochemistry and Molecular Biology
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