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https://www.readbyqxmd.com/read/28533599/the-effect-of-segmental-weight-of-prosthesis-on-hemodynamic-responses-and-energy-expenditure-of-lower-extremity-amputees
#1
Akmer Mutlu, Mohammad Dawood Kharooty, Yavuz Yakut
[Purpose] The aim of this study was to investigate the effect of segmental weight of the prosthesis on hemodynamic responses and energy expenditure in lower extremity amputees. [Subjects and Methods] Thirteen patients with a mean age of 44 ± 15.84 years and with unilateral transtibial, transfemoral and Syme's amputation were included to the study. The difference between the lightest and the heaviest prosthesis, 250 g used as the weight. All the patients completed the measurements first without weight and then with 250 g weight on the ankle joint...
April 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28532169/impact-of-metoprolol-treatment-on-cardiac-function-and-exercise-tolerance-in-heart-failure-patients-with-neuropsychiatric-disorders
#2
Jingjing Huang, Ran Zhang, Xuelu Liu, Yong Meng
OBJECTIVE: To investigate the impact of neuropsychiatric disorders on the effect of metoprolol on cardiac and motor function in chronic heart failure (CHF) patients. METHODS: From February 2013 to April 2016, CHF patients with clinical mental disorders, received metoprolol (23.75 or 47.5 mg, once daily, p.o) at the Second Affiliated Hospital of Kunming Medical University. Mental status was confirmed by means of hospital anxiety and depression scale (HADS) and Copenhagen burnout inventory (CBI) scale...
May 22, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28527879/ventricular-diastolic-pressure-ratio-as-a-marker-of-treatment-response-in-pulmonary-hypertension
#3
Arun Jose, Christopher S King, Oksana A Shlobin, Joseph M Kiernan, Nicolas A Cossa, A Whitney Brown, Steven D Nathan
BACKGROUND: Pulmonary hypertension (PH) is diagnosed and classified through right heart catheterization (RHC), with a number of hemodynamic markers used to help guide treatment decisions. These markers may not reflect the complex remodeling of the right ventricle or the interplay between ventricles, and struggle to predict treatment response. This study investigates the use of a novel marker; the ratio of left to right ventricular end-diastolic pressures (LVEDP/RVEDP), in predicting treatment outcomes in a cohort of PH patients...
May 17, 2017: Chest
https://www.readbyqxmd.com/read/28507310/molecular-and-functional-characterization-of-the-bmpr2-gene-in-pulmonary-arterial-hypertension
#4
Guillermo Pousada, Vincenzo Lupo, Sheila Cástro-Sánchez, María Álvarez-Satta, Ana Sánchez-Monteagudo, Adolfo Baloira, Carmen Espinós, Diana Valverde
Pulmonary arterial hypertension is a progressive disease that causes the obstruction of precapillary pulmonary arteries and a sustained increase in pulmonary vascular resistance. The aim was to analyze functionally the variants found in the BMPR2 gene and to establish a genotype-phenotype correlation. mRNA expression studies were performed using pSPL3 vector, studies of subcellular localization were performed using pEGFP-N1 vector and luciferase assays were performed using pGL3-Basic vector. We have identified 30 variants in the BMPR2 gene in 27 of 55 patients...
May 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28505992/the-influence-of-a-constraint-and-bimanual-training-program-using-a-variety-of-modalities-on-endurance-and-on-the-cardiac-autonomic-regulation-system-of-children-with-unilateral-cerebral-palsy-a-self-control-clinical-trial
#5
Marilyn Cohen-Holzer, Gilad Sorek, Maayan Schweizer, Michal Katz-Leurer
BACKGROUND: An intensive hybrid program, combining constraint with bimanual training, improves upper extremity function as well as walking endurance of children with unilateral cerebral palsy (UCP). Endurance improvement may be associated with the cardiac autonomic regulation system (CARS) adaptation, known to be impaired among these children. OBJECTIVE: To examine the influence of an intensive hybrid program on CARS, walking endurance and the correlation with upper extremity function of children with UCP...
May 11, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28503450/balance-assessment-in-subacute-stroke-patients-using-the-balance-control-trainer-balpro
#6
Jin Won Song, Jong Min Kim, Youn Soo Cheong, Yang-Soo Lee, Seong Min Chun, Yu-Sun Min, Tae-Du Jung
OBJECTIVE: To demonstrate the efficacy of the balance control trainer (BCT), developed for training patients with balance problems, as a balance assessment tool in subacute stroke patients. METHODS: A prospective cross-sectional study was carried out on 38 subacute stroke patients in their first episode of a stroke, and having the ability to maintain a standing position without aid for at least 5 minutes. Patients were assessed using the BCT (BalPro) 43.7±35.7 days after stroke...
April 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28501523/a-new-clinically-applicable-measure-of-functional-status-in-patients-with-heart%C3%A2-failure-the-60-foot-walk-test
#7
Kristie M Harris, David S Krantz, Willem J Kop, Joanne Marshall, Shawn W Robinson, Jennifer M Marshall, Stephen S Gottlieb
OBJECTIVES: This study reports the development and predictive value of the 60-foot walk test (60ftWT), a brief functional status measure for patients with heart failure (HF). The goal was to develop a test suitable for clinical settings and appropriate for patients with walking impairments. BACKGROUND: The 6-min walk test (6MWT) has considerable predictive value, but requires a long walking course and has limited utility in patients with mobility-related comorbidities...
May 2, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28490242/-telemetry-data-based-on-comparative-study-of-physical-activity-in-patients-with-resynchronization-device
#8
Csaba Melczer, László Melczer, Ilona Goják, Attila Kónyi, Sándor Szabados, L Bence Raposa, András Oláh, Pongrác Ács
INTRODUCTION: The effect of regular physical activity on health is widely recognized, but several studies have shown its key importance for heart patients. AIM: The present study aimed to define the PA % values, and to convert them into metabolic equivalent values (MET), which describes oxygen consumption during physical activity. METHOD: A total of seventeen patients with heart disease; 3 females and 14 males; age: 57.35 yrs ± 9.54; body mass 98...
May 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28488885/respiratory-muscle-strength-and-pulmonary-function-in-children-with-rhinitis-and-asthma-after-a-six-minute-walk-test
#9
Ana Alice de Almeida Soares, Camila Moraes Barros, Cássia Giulliane Costa Santos, Maria Renata Aragão Dos Santos, José Rodrigo Santos Silva, Walderi Monteiro da Silva Junior, Silvia de Magalhães Simões
OBJECTIVE: Rhinitis and asthma decrease quality of life. Few studies have assessed the performance of children with asthma or rhinitis under submaximal exercise. We evaluated maximal respiratory pressures, spirometric parameters, and ability to sustain submaximal exercise in these children before and after the 6-minute walk test (6MWT), compared to healthy children. METHODS: This cross-sectional, analytical study included 89 children aged 6-12 years in outpatient follow-up: 27 healthy (H), 31 with rhinitis (R), and 31 with mild asthma under control (A)...
May 10, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28486559/online-mindfulness-as-a-promising-method-to-improve-exercise-capacity-in-heart-disease-12-month-follow-up-of-a-randomized-controlled-trial
#10
Rinske A Gotink, John O Younge, Machteld F Wery, Elisabeth M W J Utens, Michelle Michels, Dimitris Rizopoulos, Liesbeth F C van Rossum, Jolien W Roos-Hesselink, Myriam M G Hunink
There is increasing evidence that mindfulness can reduce stress, and thereby affect other psychological and physiological outcomes as well. Earlier, we reported the direct 3-month results of an online modified mindfulness-based stress reduction training in patients with heart disease, and now we evaluate the effect at 12-month follow-up. 324 patients (mean age 43.2 years, 53.7% male) were randomized in a 2:1 ratio to additional 3-month online mindfulness training or to usual care alone. The primary outcome was exercise capacity measured with the 6 minute walk test (6MWT)...
2017: PloS One
https://www.readbyqxmd.com/read/28475703/cibinetide-improves-corneal-nerve-fiber-abundance-in-patients-with-sarcoidosis-associated-small-nerve-fiber-loss-and-neuropathic-pain
#11
Daniel A Culver, Albert Dahan, Daiva Bajorunas, Maria Jeziorska, Monique van Velzen, Leon P H J Aarts, Jinny Tavee, Martijn R Tannemaat, Ann N Dunne, Rita I Kirk, Ioannis N Petropoulos, Anthony Cerami, Rayaz A Malik, Michael Brines
Purpose: Sarcoidosis frequently is complicated by small nerve fiber loss (SNFL), which can be quantified using corneal confocal microscopy (CCM). Prior studies suggest that the innate repair receptor agonist cibinetide reverses corneal nerve loss. This phase 2b, 28-day, randomized trial of 64 subjects with sarcoid-associated SNFL and neuropathic pain assessed the effect of cibinetide on corneal nerve fiber area (CNFA) and regenerating intraepidermal fibers (GAP-43+) as surrogate endpoints for disease modification, pain severity, and functional capacity (6-minute walk test [6MWT])...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28474651/squat-to-stand-test-in-functional-assessment-of-stable-chronic-obstructive-pulmonary-disease-patients
#12
Prahlad Rai Gupta, Asif Feroz, Sachet Dawar, Harshdeep Bhangoo, Shivani Swami, T K Khublani
BACKGROUND: Assessment of functional status is vital for proper therapy and rehabilitation programs in chronic obstructive pulmonary disease (COPD) patients. Traditionally, 6 min walk test (6MWT) has been used but it by itself may not reflect the total functional status in these patients as it poorly correlates to the disease severity. A sit-to-stand test (STST) has been proposed as a better alternative to 6MWT but to test their ability to stand from the squatting position, i.e., a squat-to-stand test (SqTST) will be more appropriate in rural patients...
May 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/28473284/energy-expenditure-and-cost-of-walking-and-stair-climbing-in-individuals-with-chronic-stroke
#13
Janaine C Polese, Giane A Ribeiro-Samora, Raquel C Lana, Fátima V Rodrigues-De-Paula, Luci F Teixeira-Salmela
BACKGROUND: Subjects with stroke show higher energy cost (EC) during walking, when compared to healthy individuals, but the mechanisms are not fully understood. Additionally, the behavior of physiological variables during other activities has not been investigated. OBJECTIVES: To investigate energy expenditure (EE) and EC during the six-minute walking test (6MWT) and stair climb test (SCT) in chronic stroke subjects compared to healthy controls. METHODS: Cross-sectional study in which stroke subjects (n=18) (community-walking speed ≥0...
April 13, 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28473280/safety-of-early-performance-of-the-six-minute-walk-test-following-acute-myocardial-infarction-a-cross-sectional-study
#14
Lívia S Diniz, Victor R Neves, Ana C Starke, Marco P T Barbosa, Raquel R Britto, Antônio L P Ribeiro
BACKGROUND: The six-minute walk test (6MWT) is a simple, low cost, reliable, and valid method for evaluating the functional capacity of cardiac patients. However, its early use and safety following acute myocardial infarction (AMI) is recent and has been little investigated. OBJECTIVE: To evaluate and to compare the safety and the cardiac behavior of early performance of the 6MWT in patients following uncomplicated AMI up to 4 days or more than 4 days after the event...
April 8, 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28468260/6mwt-performance-and-its-correlations-with-vo%C3%A2-and-handgrip-strength-in-home-dwelling-mid-aged-and-older-chinese
#15
Qing Zhang, Hailin Lu, Shiqin Pan, Yuan Lin, Kun Zhou, Li Wang
Six-minute walk test (6MWT) performance is more commonly used in clinic patients with chronic cardiopulmonary diseases but not in home-dwelling individuals of similar age, and its correlations with oxygen uptake (VO₂) and muscle strength require further investigation. The current study determined the 6MWT performance of 106 home-dwelling residents (mean age of 62 years) in Suzhou, China. VO₂ at a respiratory exchange ratio (R) of 1 was measured through graded cycling exercise tests on 46 participants. Handgrip strength of all participants was tested...
April 29, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28465220/the-six-minute-walk-6mwt-as-a-measure-walking-capacity-wc-in-ambulatory-individual-with-amyotrophic-lateral-sclerosis-ambals
#16
Mohammed Sanjak, Velma Langford, Scott Holsten, Nigel Rozario, Charity G Moore Patterson, Elena Bravver, William L Bockenek, Benjamin R Brooks
OBJECTIVE: To determine the validity of the 6MWT as an outcome measure to evaluate WC in ambALS. DESIGN: Observational study. Participants performed 6MWT, 25FWT, TUG, lower extremity maximum voluntary isometric contraction (MVIC), ALSFRS-R, and forced vital capacity (FVC). SETTING: Multidisciplinary ALS clinic at an academic medical center. PARTICIPANTS: AmbALS (N=186) who ambulate without (stage I) or with (stage II) assistive device...
April 29, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28462519/effect-of-ivabradine-in-patients-with-heart-failure-with-preserved-ejection-fraction-the-edify-randomized-placebo-controlled-trial
#17
Michel Komajda, Richard Isnard, Alain Cohen-Solal, Marco Metra, Burkert Pieske, Piotr Ponikowski, Adriaan A Voors, Fabienne Dominjon, Cécile Henon-Goburdhun, Matthieu Pannaux, Michael Böhm
AIMS: This randomized, double-blind, placebo-controlled trial assessed whether heart rate (HR) reduction with ivabradine improves cardiac function in heart failure with preserved ejection fraction (HFpEF). METHODS AND RESULTS: The prEserveD left ventricular ejectIon fraction chronic heart Failure with ivabradine studY (EDIFY) included 179 patients in New York Heart Association (NYHA) classes II and III, in sinus rhythm, with HR of ≥70 b.p.m., NT-proBNP of ≥220 pg/mL (BNP ≥80 pg/mL) and left ventricular ejection fraction of ≥45%...
April 30, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28460707/could-peak-oxygen-uptake-be-estimated-from-proposed-equations-based-on-the-six-minute-walk-test-in-chronic-heart-failure-subjects
#18
Giane A Ribeiro-Samora, Dayane Montemezzo, Danielle A G Pereira, Thaysa L Tagliaferri, Otávia A Vieira, Raquel R Britto
OBJECTIVES: To evaluate the agreement between the measured peak oxygen uptake (VO2peak) and the VO2peak estimated by four prediction equations based on the six-minute walk test (6MWT) in chronic heart failure patients. METHOD: Thirty-six chronic heart failure patients underwent cardiopulmonary exercise testing and the 6MWT to assess their VO2peak. Four previously published equations that include the variable six-minute walk distance were used to estimate the VO2peak: Cahalin, 1996a (1); Cahalin, 1996b (2); Ross, 2010 (3); and Adedoyin, 2010 (4)...
March 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28459605/objectively-measured-daily-life-physical-activity-of-moderate-to-severe-brazilian-asthmatic-women-in-comparison-to-healthy-controls-a-cross-sectional-study
#19
Cristina Martins Coelho, Larissa Almeida Campos, Fabiana Oliveira Pereira, Ranieri Monteiro Cardoso, Lucas Mendes Nascimento, Jessica Blanc Leite Oliveira, Lucas Ricardo Andrade, Erich Vidal Carvalho, Maycon Moura Reboredo, Bruno Valle Pinheiro
Considering the complex relationship between asthma symptoms and exercise, asthmatics are usually believed to be less active in daily life than healthy subjects. However, few studies have objectively assessed daily-life physical activity (DLPA) of asthmatic adults. OBJECTIVE: To objectively assess DLPA of a sample of Brazilian asthmatic women in comparison to healthy controls, and to investigate the associations between DLPA and asthma control, health-related quality of life, anxiety and depression levels, and the Six-minute walk test (6MWT) in this population...
May 1, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28459237/effects-of-feiwei-granules-in-the-treatment-of-idiopathic-pulmonary-fibrosis-a-randomized-and-placebo-controlled-trial
#20
Yang Yu, Zengtao Sun, Liqing Shi, Yanping Zhang, Zhaoshan Zhou, Shunan Zhang, Enxiang Chao
OBJECTIVE: To document the therapeutic effects of Feiwei granules (FGs) for idiopathic pulmonary fibrosis (IPF). METHODS: One hundred cases with IPF were randomized into the treatment group (80) and control group (20). Both groups were given basic treatment with prednisone. The treatment group was given FGs, and the control group was given Jinshuibao capsules (JCs). Treatment lasted for 6 months. The Medical Research Council Dyspnea Scale (MRCDS), the Saint George's Hospital Respiratory Questionnaire (SGHRQ), pulmonary function, the Traditional Chinese Medicine Syndrome Score (TCMSS), 6-min walking test (6MWT) and blood gas analyses were recorded before the study as well as 3 months and 6 months after treatment...
August 2016: Journal of Traditional Chinese Medicine, Chung i Tsa Chih Ying Wen Pan
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