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Tenectaplase

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https://www.readbyqxmd.com/read/27843802/coronary-ectasia-in-a-man-on-breast-cancer-therapy-presenting-with-acute-coronary-syndrome
#1
Dana C Johnson, Luay Rifai, Parag V Patel
Limited data exist on the association between breast cancer treatments and coronary artery disease anatomy, particularly in males. We describe an unusual case of diffuse coronary ectasia in a man with breast cancer presenting with acute coronary syndrome (ACS). A 66-year-old man with breast cancer on paclitaxel, tamoxifen, and carboplatin chemotherapy regimen, presents with new onset chest pain. Electrocardiogram reveals anterolateral ST-segment depressions and elevated troponin I level. Emergent angiography revealed grossly ectatic coronary arteries with a total thrombotic occlusion of the mid right coronary artery...
October 2016: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/22688929/successful-treatment-of-st-elevation-myocardial-infarction-caused-by-septic-embolus-with-the-use-of-a-thrombectomy-catheter-in-infective-endocarditis
#2
John Whitaker, Mrinal Saha, Rahul Fulmali, Divaka Perera
A 71-year-old patient suffered a transmural (ST elevation) myocardial infarction (MI) as a result of a septic embolus from an infected tissue aortic valve replacement. Following failed fibrinolysis, his MI was successfully treated with thrombectomy using an export catheter. He suffered bleeding complications following the administration of tenectaplase and required aortic valve and root replacement due to ongoing systemic embolisation.
2011: BMJ Case Reports
https://www.readbyqxmd.com/read/22624282/future-of-thrombolytic-therapy-an-indian-context
#3
J S Hiremath
Acute myocardial infarction has two main treatment modalities in the form of direct angioplasty (PAMI) and intravenous thrombolysis. PAMI is statistically clearly superior to intravenous thrombolysis. However, as ground reality in Indian conditions PAMI remains a distant ideal option for many ST elevation MI patients. In order to bridge the gap between IV thrombolysis and PAMI, early/pre-hospital IV thrombolysis to all and early angiography within 3 to 24 hours is the treatment modality, which needs to be exercised in India...
December 2011: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/18082502/guideline-adjudicated-fibrinolytic-failure-incidence-findings-and-management-in-a-contemporary-clinical-trial
#4
RANDOMIZED CONTROLLED TRIAL
Christopher E Buller, Robert C Welsh, Cynthia M Westerhout, John G Webb, Blair O'Neill, Richard Gallo, Paul W Armstrong
BACKGROUND: Rescue percutaneous coronary intervention (PCI) is efficacious after clinical failure of fibrinolytic therapy and is recommended for those with persistent ischemia, hemodynamic, or electrical instability. We sought to describe the frequency of fibrinolytic failure (rescue eligibility) as well as the patient characteristics associated with rescue eligibility, rescue referral, and PCI. METHODS AND RESULTS: Eligibility, indication, and referral for guideline-based rescue PCI were adjudicated in 221 patients enrolled in the WEST trial...
January 2008: American Heart Journal
https://www.readbyqxmd.com/read/15131541/association-of-the-timing-of-st-segment-resolution-with-timi-myocardial-perfusion-grade-in-acute-myocardial-infarction
#5
C Michael Gibson, Juhana Karha, Robert P Giugliano, Mathew T Roe, Sabina A Murphy, Robert A Harrington, Cindy L Green, Marc J Schweiger, Jerry S Miklin, Kenneth W Baran, Sebastian Palmeri, Eugene Braunwald, Mitchell W Krucoff et al.
BACKGROUND: More complete ST-segment resolution (ST res) in acute myocardial infarction (MI) has been associated with better epicardial and myocardial reperfusion as assessed with the Thrombolysis in Myocardial Infarction (TIMI) flow grade (TFG) and the TIMI myocardial perfusion grade (TMPG), respectively. However, no data exist comparing the speed of ST resolution on continuous electrocardiogram (ECG) monitoring with the TMPG on coronary angiography. We hypothesized that delayed ST res is associated with impaired TMPGs...
May 2004: American Heart Journal
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