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https://www.readbyqxmd.com/read/29036954/-relationship-between-highly-sensitive-cardiac-troponin-t-and-sepsis-and-outcome-in-critically-ill-patients
#1
T T Wang, L Jiang
Objective: To investigate the prognostic value of highly sensitive cardiac Troponin T (hs-cTn T) for sepsis in critically ill patients. Methods: Patients estimated to stay in the ICU of Fuxing Hospital for more than 24h were enrolled at from March 2014 to December 2014. Serum hs-cTn T was tested within two hours. Univariate and multivariate linear regression analyses were used to determine the association of variables with the hs-cTn T. Multivariable logistic regression analysis was used to evaluate the risk factors of 28-day mortality...
October 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29036855/diagnostic-criteria-for-persistent-postural-perceptual-dizziness-pppd-consensus-document-of-the-committee-for-the-classification-of-vestibular-disorders-of-the-b%C3%A3-r%C3%A3-ny-society
#2
Jeffrey P Staab, Annegret Eckhardt-Henn, Arata Horii, Rolf Jacob, Michael Strupp, Thomas Brandt, Adolfo Bronstein
This paper presents diagnostic criteria for persistent postural-perceptual dizziness (PPPD) to be included in the International Classification of Vestibular Disorders (ICVD). The term PPPD is new, but the disorder is not. Its diagnostic criteria were derived by expert consensus from an exhaustive review of 30 years of research on phobic postural vertigo, space-motion discomfort, visual vertigo, and chronic subjective dizziness. PPPD manifests with one or more symptoms of dizziness, unsteadiness, or non-spinning vertigo that are present on most days for three months or more and are exacerbated by upright posture, active or passive movement, and exposure to moving or complex visual stimuli...
October 7, 2017: Journal of Vestibular Research: Equilibrium & Orientation
https://www.readbyqxmd.com/read/29036843/aberrant-peak-lactate-response-in-ms
#3
Kathrin Schlüter, Josephina Maier, Stefan Patra, Stefan M Gold, Christoph Heesen, Karl-Heinz Schulz
BACKGROUND: The peak blood lactate response to an exhaustive exercise test in a number of chronic conditions has been shown to differ from that seen in healthy, untrained individuals. However, this has not been investigated for patients with multiple sclerosis (MS). OBJECTIVE: The main objective was to determine and compare the peak blood lactate response to exercise and the maximal workload between two groups of MS patients with different illness severity. METHODS: Twenty-five patients with a relapsing-remitting disease course (Group RR) and 41 patients with a secondary- or primary chronic progressive disease course (group CP) performed an exhaustive incremental bicycle ergometry...
October 11, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/29036731/rethinking-body-ownership-in-schizophrenia-experimental-and-meta-analytical-approaches-show-no-evidence-for-deficits
#4
Albulena Shaqiri, Maya Roinishvili, Mariia Kaliuzhna, Ophélie Favrod, Eka Chkonia, Michael H Herzog, Olaf Blanke, Roy Salomon
Schizophrenia is a severe psychiatric disorder, in which patients experience an abnormal sense of self. While deficits in sensorimotor self-representation (agency) are well documented in schizophrenia, less is known about other aspects of bodily self-representation (body ownership). Here, we tested a large cohort (N = 59) of chronic schizophrenia patients and matched controls (N = 30) on a well-established body illusion paradigm, the Full Body Illusion (FBI). In this paradigm, changes in body ownership are induced through prolonged multisensory stimulation, in which participants are stroked on their back while seeing the stroking on the back of a virtual body...
July 25, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29036727/economic-labor-and-regulatory-moderators-of-the-effect-of-individual-placement-and-support-among-people-with-severe-mental-illness-a-systematic-review-and-meta-analysis
#5
Justin D Metcalfe, Robert E Drake, Gary R Bond
As Individual Placement and Support (IPS) has become the international standard for vocational rehabilitation of adults with serious mental illness, researchers must consider the relationship between IPS and local environments. This meta-analysis used mixed-effects meta-regressions to assess the impact of site-level moderators on the likelihood that IPS recipients, compared with recipients of alternative vocational services, achieved competitive employment. Potential moderators included change in gross domestic product (GDP), local unemployment and unionization rates, and indices describing employment protection regulations, level of disability benefits compensation, and efforts to integrate people with disabilities into the workforce...
September 28, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29036718/glutamatergic-response-to-heat-pain-stress-in-schizophrenia
#6
Joshua Chiappelli, Qiaoyun Shi, Sarah Andrea Wijtenburg, Raimi Quiton, Krista Wisner, Frank Gaston, Priyadurga Kodi, Christopher Gaudiot, Peter Kochunov, Laura M Rowland, Liyi Elliot Hong
Regulation of stress response involves top-down mechanisms of the frontal-limbic glutamatergic system. As schizophrenia is associated with glutamatergic abnormalities, we hypothesized that schizophrenia patients may have abnormal glutamatergic reactivity within the dorsal anterior cingulate cortex (dACC), a key region involved in perception of and reaction to stress. To test this, we developed a somatic stress paradigm involving pseudorandom application of safe but painfully hot stimuli to the forearm of participants while they were undergoing serial proton magnetic resonance spectroscopy to measure changes in glutamate and glutamine levels in the dACC...
September 23, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29036471/immunization-completion-in-infants-born-at-low-birth-weight
#7
Matt Nestander, Jay Dintaman, Apryl Susi, Gregory Gorman, Elizabeth Hisle-Gorman
Background: Low birth weight (LBW) has been associated with underimmunization. We sought to understand the effect of LBW on immunization completion after controlling for previously hypothesized mediators, including prematurity, neonatal illness, well-child care, non-well-child visits, and provider consistency. Methods: We formed a retrospective cohort of infants born between 2008 and 2011 with ≥2 years of military healthcare follow-up. International Classification of Diseases, Ninth Revision codes were used to identify LBW, preterm birth, neonatal illnesses, well-child visits, non-well-child visits, provider consistency, and parental rank in the inpatient and outpatient records...
September 23, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29036464/the-mimic-code-repository-enabling-reproducibility-in-critical-care-research
#8
Alistair E W Johnson, David J Stone, Leo A Celi, Tom J Pollard
Objective: Lack of reproducibility in medical studies is a barrier to the generation of a robust knowledge base to support clinical decision-making. In this paper we outline the Medical Information Mart for Intensive Care (MIMIC) Code Repository, a centralized code base for generating reproducible studies on an openly available critical care dataset. Materials and Methods: Code is provided to load the data into a relational structure, create extractions of the data, and reproduce entire analysis plans including research studies...
September 27, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/29036388/risk-factors-for-suicidality-in-patients-with-schizophrenia-a-systematic-review-meta-analysis-and-meta-regression-of-96-studies
#9
Ryan Michael Cassidy, Fang Yang, Flávio Kapczinski, Ives Cavalcante Passos
The lifetime risk of suicide and suicide attempt in patients with schizophrenia are 5% and 25%-50%, respectively. The current meta-analysis aims to determine risk factors associated with suicidality in subjects with schizophrenia. We searched Pubmed, Web of Science, EMBASE, and the reference lists of included studies. Inclusion criteria were met if an article reported a dichotomous sample of patients with schizophrenia with suicidal ideation, attempted suicide, or suicide compared to patients without. We also performed a cohort study meta-analysis as a supplemental analysis...
September 23, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29036378/the-effect-of-costs-on-kenyan-households-demand-for-medical-care-why-time-and-distance-matter
#10
Matt Kukla, Niccie McKay, Richard Rheingans, Jeff Harman, Jessica Schumacher, Karen L Kotloff, Myrone M Levine, Robert Breiman, Tamer Farag, Damian Walker, Dilruba Nasrin, Richard Omore, Ciara O'Reilly, Eric Mintz
In an environment of constrained resources, policymakers must identify solutions for financing and delivering health services that are efficient and sustainable. However, such solutions require that policymakers understand the complex interaction between household utilization patterns, factors influencing household medical decisions, and provider performance. This study examined whether and under what conditions out-of-pocket, transportation, and time costs influenced Kenyan households' choice of medical provider for childhood diarrhoeal illnesses...
October 5, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/29036258/serpiginous-purpuric-eruption-of-the-leg
#11
Kristin Totoraitis, Cynthia M Magro, Adam Friedman
A previously healthy 68-year-old male presented with a rash on his right lower leg. The lesions had spread along the leg since onset 9 days prior, and the patient reported localized soreness and pruritus. He denied systemic symptoms including fever, fatigue, myalgia, joint pain, and recent illness. Physical examination revealed a serpiginous, purpuric eruption on the anterior and posterior right thigh and lower leg. A 4mm punch biopsy from the right lower leg revealed a Th2 dominant process reflective of a type IV delayed hypersensitivity reaction...
October 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29036219/correction-role-of-mitochondrial-dna-damage-and-dysfunction-in-veterans-with-gulf-war-illness
#12
Yang Chen, Joel N Meyer, Helene Z Hill, Gudrun Lange, Michael R Condon, Jacquelyn C Klein, Duncan Ndirangu, Michael J Falvo
[This corrects the article DOI: 10.1371/journal.pone.0184832.].
2017: PloS One
https://www.readbyqxmd.com/read/29036206/risk-characterization-of-hospitalizations-for-mental-illness-and-or-behavioral-disorders-with-concurrent-heat-related-illness
#13
Michael T Schmeltz, Janet L Gamble
BACKGROUND: Many studies have found significant associations between high ambient temperatures and increases in heat-related morbidity and mortality. Several studies have demonstrated that increases in heat-related hospitalizations are elevated among individuals with diagnosed mental illnesses and/or behavioral disorders (MBD). However, there are a limited number of studies regarding risk factors associated with specific mental illnesses that contribute, at least in part, to heat-related illnesses (HRI) in the United States...
2017: PloS One
https://www.readbyqxmd.com/read/29036136/correlation-based-evaluation-of-visual-performance-to-reduce-the-statistical-error-of-visual-acuity
#14
Csilla Fülep, Illés Kovács, Kinga Kránitz, Gábor Erdei
Ophthalmologists evaluate visual acuity tests by the number of correctly recognized optotypes (usually letters) in the different lines of an eye chart. This probability-based scoring results in significant statistical error that can only be decreased by the time-consuming analysis of a larger number of optotypes. In this paper, we present a new, more precise correlation-based scoring method that takes the degree of misidentification into consideration too, rather than the mere fact of it. According to our experimental results, this new method decreases the uncertainty error by 28% if using the same number of optotypes at a given letter size or requires half the optotype number to produce the same error as that of probability-based scoring...
July 1, 2017: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/29036112/improving-color-constancy-by-discounting-the-variation-of-camera-spectral-sensitivity
#15
Shao-Bing Gao, Ming Zhang, Chao-Yi Li, Yong-Jie Li
It is an ill-posed problem to recover the true scene colors from a color biased image by discounting the effects of scene illuminant and camera spectral sensitivity (CSS) at the same time. Most color constancy (CC) models have been designed to first estimate the illuminant color, which is then removed from the color biased image to obtain an image taken under white light, without the explicit consideration of CSS effect on CC. This paper first studies the CSS effect on illuminant estimation arising in the inter-dataset-based CC (inter-CC), i...
August 1, 2017: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/29035924/rotational-therapy-in-thoracic-injuries-what-is-the-evidence
#16
Philipp Störmann, Ingo Marzi, Sebastian Wutzler
PURPOSE OF REVIEW: To review the current use of continuous lateral rotational therapy (CLRT) in patients with thoracic injuries and its impact on clinical course, complications and outcome. RECENT FINDINGS: Patient positioning is a key factor in the treatment of severe thoracic injuries and CLRT, and intermittent supine and prone position are basic options. There is a lack of randomized controlled studies for trauma patients with chest injury undergoing kinetic therapy as standard of care...
October 14, 2017: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/29035909/dysregulated-myelopoiesis-and-hematopoietic-function-following-acute-physiologic-insult
#17
Tyler J Loftus, Alicia M Mohr, Lyle L Moldawer
PURPOSE OF REVIEW: The purpose of this review is to describe recent findings in the context of previous work regarding dysregulated myelopoiesis and hematopoietic function following an acute physiologic insult, focusing on the expansion and persistence of myeloid-deriver suppressor cells, the deterioration of lymphocyte number and function, and the inadequacy of stress erythropoiesis. RECENT FINDINGS: Persistent myeloid-derived suppressor cell (MDSC) expansion among critically ill septic patients is associated with T-cell suppression, vulnerability to nosocomial infection, chronic critical illness, and poor long-term functional status...
October 13, 2017: Current Opinion in Hematology
https://www.readbyqxmd.com/read/29035838/effect-of-two-treatment-protocols-for-ketosis-on-the-resolution-postpartum-health-milk-yield-and-reproductive-outcomes-of-dairy-cows
#18
Jae-Kwan Jeong, In-Soo Choi, Sung-Ho Moon, Soo-Chan Lee, Hyun-Gu Kang, Young-Hun Jung, Soo-Bong Park, Ill-Hwa Kim
We determined the effect of ketosis treatment with propylene glycol (PG) or PG plus l-carnitine and methionine (Metabolase(®), Fatro, Bologna, Italy) on the resolution, postpartum health, milk yield, and reproductive performances of dairy cows. Blood from 475 Holstein cows was collected weekly until 4 weeks after calving to measure blood β-hydroxybutyrate (BHBA) concentrations. Cows with blood BHBA concentration ≥1.2 mmol/L were diagnosed with ketosis and were enrolled. One hundred and fifty cows diagnosed with ketosis were randomly assigned to three treatment groups (Day 0): (1) PG (300 g, PO) for 3 days (PG group, n = 50), (2) PG (300 g, PO) plus l-carnitine (1...
September 25, 2017: Theriogenology
https://www.readbyqxmd.com/read/29035757/pulmonary-hypertension-associated-with-bronchopulmonary-dysplasia-in-preterm-infants
#19
REVIEW
Christine B Bui, Merrin A Pang, Arvind Sehgal, Christiane Theda, Jason C Lao, Philip J Berger, Marcel F Nold, Claudia A Nold-Petry
Bronchopulmonary dysplasia (BPD) and BPD-associated pulmonary hypertension (BPD-PH) are chronic inflammatory cardiopulmonary diseases with devastating short- and long-term consequences for infants born prematurely. The immature lungs of preterm infants are ill-prepared to achieve sufficient gas exchange, thus usually necessitating immediate commencement of respiratory support and oxygen supplementation. These therapies are life-saving, but they exacerbate the tissue damage that is inevitably inflicted on a preterm lung forced to perform gas exchange...
October 2, 2017: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/29035733/how-does-parental-cancer-affect-adolescent-and-young-adult-offspring-a-systematic-review
#20
REVIEW
Adam Walczak, Fiona McDonald, Pandora Patterson, Katherine Dobinson, Kimberley Allison
OBJECTIVES: To i) identify and synthesise evidence published since 2007 regarding the impact of parental cancer on adolescent and young adult offspring, ii) identify methodological and evidence gaps addressed during this period and iii) highlight those requiring further attention. DESIGN: A systematic review and thematic synthesis of peer reviewed literature regarding the impact of parental cancer upon AYA offspring. DATA SOURCES: Online searches of CINAHL, Embase, Medline, PsychInfo and Scopus databases were conducted...
September 1, 2017: International Journal of Nursing Studies
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