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https://www.readbyqxmd.com/read/29912140/three-year-survival-comparison-between-transcatheter-and-surgical-aortic-valve-replacement-for-intermediate-and-low-risk-patients
#1
Juan A Siordia, Jackquelin M Loera, Matt Scanlon, Jessie Evans, Peter A Knight
Transcatheter aortic valve implantation is a suitable therapeutic intervention for patients deemed inoperable or high risk for surgical aortic valve replacement. Current investigations question whether it is a suitable alternative to surgery for intermediate- and low-risk patients. The following meta-analysis presents a comparison between transcatheter versus surgical aortic valve replacement in patients that are intermediate and low risk for surgery. Articles were collected via an electronic search using Google Scholar and PubMed...
June 14, 2018: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29909860/outcomes-and-associated-factors-in-malpractice-litigation-involving-inferior-vena-cava-filters
#2
REVIEW
Kenny Oh, Anil Hingorani
OBJECTIVE: Placement of inferior vena cava (IVC) filters is a controversial focus of medical malpractice. Clinicians currently have little information to guide them regarding key issues and outcomes in litigation. In this retrospective legal case review, we analyzed the factors associated with malpractice actions involving IVC filters. METHODS: The legal databases LexisNexis and Westlaw were searched from 1967 to 2016 for all published legal cases in the United States involving placement of IVC filters...
July 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29909856/pulmonary-thromboembolic-events-in-patients-with-congenital-lipomatous-overgrowth-vascular-malformations-epidermal-nevi-and-spinal-skeletal-abnormalities-and-klippel-tr%C3%A3-naunay-syndrome
#3
Joseph Reis, Ahmad I Alomari, Cameron C Trenor, Denise M Adams, Steven J Fishman, Samantha A Spencer, Raja Shaikh, Anna P Lillis, Murali K Surnedi, Gulraiz Chaudry
OBJECTIVE: Patients with Klippel-Trénaunay syndrome (KTS) and congenital lipomatous overgrowth, vascular malformations, epidermal nevi, and spinal/skeletal abnormalities (CLOVES) syndrome have central phlebectasia and enlarged persistent embryonic veins that are often incompetent and prone to thromboembolism. The purpose of the study was to determine the presence of phlebectasia and the incidence of symptomatic pulmonary embolism (PE). METHODS: A retrospective review was conducted of patients referred to the Vascular Anomalies Center at our institution during a 21-year period who were diagnosed with KTS and CLOVES syndrome...
July 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29909687/comparative-efficacy-of-autologous-stromal-vascular-fraction-and-autologous-adipose-derived-mesenchymal-stem-cells-combined-with-hyaluronic-acid-for-the-treatment-of-sheep-osteoarthritis
#4
Xiaoteng Lv, Jiyin He, Xue Zhang, Xuan Luo, Na He, Zhongwei Sun, Huitang Xia, Victor Liu, Li Zhang, Xiangming Lin, Liping Lin, Huabin Yin, Dong Jiang, Wei Cao, Richard Wang, Guangdong Zhou, Wen Wang
The current study explored whether intra-articular (IA) injection of autologous adipose mesenchymal stem cells (ASCs) combined with hyaluronic acid (HA) achieved better therapeutic efficacy than autologous stromal vascular fraction (SVF) combined with HA to prevent osteoarthritis (OA) progression and determined how long autologous ASCs combined with HA must remain in the joint to observe efficacy. OA models were established by performing anterior cruciate ligament transection (ACLT) and medial meniscectomy (MM)...
January 1, 2018: Cell Transplantation
https://www.readbyqxmd.com/read/29908709/shorter-interval-between-radiation-therapy-and-salvage-laryngopharyngeal-surgery-increases-complication-rates-following-microvascular-free-tissue-transfer
#5
Eric J Formeister, A Sean Alemi, Ivan El-Sayed, Jonathan R George, Patrick Ha, P Daniel Knott, William R Ryan, Rahul Seth, Matthew L Tamplen, Chase M Heaton
PURPOSE: To evaluate how the interval between radiation and salvage surgery for advanced laryngeal cancer with free tissue transfer reconstruction influences complication rates. MATERIALS AND METHODS: This is a retrospective series of 26 patients who underwent salvage laryngectomy or laryngopharyngectomy with vascularized free tissue reconstruction (anterolateral thigh or radial forearm) following radiation or chemoradiation between 2012 and 2017 at a single academic center...
June 6, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29908372/association-of-fibrotic-remodeling-and-cytokines-chemokines-content-in-epicardial-adipose-tissue-with-atrial-myocardial-fibrosis-in-patients-with-atrial-fibrillation
#6
Ichitaro Abe, Yasushi Teshima, Hidekazu Kondo, Haruka Kaku, Shintaro Kira, Yuki Ikebe, Shotaro Saito, Akira Fukui, Tetsuji Shinohara, Kunio Yufu, Mikiko Nakagawa, Naoki Hijiya, Masatsugu Moriyama, Tatsuo Shimada, Shinji Miyamoto, Naohiko Takahashi
BACKGROUND: Epicardial adipose tissue (EAT) is associated with atrial fibrillation (AF), but the underlying mechanisms remain to be fully elucidated. OBJECTIVE: Using human left atrial appendage (LAA) samples, we examined the interactive relationship between the EAT profile and atrial myocardial fibrosis through histological and biochemical analyses. METHODS: LAA samples were obtained from 59 consecutive AF patients during cardiovascular surgery...
June 13, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29908198/in-hospital-delays-result-in-worse-patient-outcomes-and-higher-cost-after-cardiac-surgery
#7
Diane R M Somlo, Nelson P Repenning, Abeel A Mangi
BACKGROUND: Contemporary reimbursement systems allow hospitals to maintain profitability by offering procedural services. However, increasing procedural volume can be met with structural inefficiencies that in turn cause delays, worse patient outcomes, and increased cost. METHODS: A multidisciplinary team assessed operations and outcomes at the Heart and Vascular Center at Yale New Haven Hospital, a tertiary academic medical center. Data were analyzed retrospectively to assess delays in transferring patients between care environments, patient outcomes, and cost...
June 13, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29907461/vascular-anomalies
#8
REVIEW
Amir H Taghinia, Joseph Upton
Vascular anomalies encompass a wide variety of clinical conditions involving the vasculature. Over the past several decades, the terminology has changed as our understanding of these conditions has improved. A well-accepted classification scheme has evolved with constant additions, updates, and revisions. Imaging techniques have also advanced with greater resolution and a better understanding of the correlation between imaging, clinical behavior, and natural history. Meanwhile, the treatment of these conditions has also changed, with greater focus on minimally invasive techniques as opposed to radical surgery...
June 12, 2018: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29906812/congenital-arteriovenous-malformation-of-the-scalp-involving-the-orbit
#9
Alberto Feletti, Stavros Dimitriadis, Stefano Vallone, Giacomo Pavesi
BACKGROUND:  Arteriovenous malformations (AVMs) of the scalp are rare and infrequently encountered by the neurosurgeon. CASE DESCRIPTION:  We report a unique case of a 42-year-old patient who presented with a progressive worsening of visual acuity in the right eye (lower quadrantanopia) and palpebral ptosis. Physical examination revealed a right exophthalmos and a right frontoparietal scalp soft swelling when the patient was in the supine position. Neurologic work-up showed a scalp AVM extending into the orbit and connected to an intraorbital cavernous angioma...
June 15, 2018: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/29906242/angiotensin-ii-receptor-i-blockade-prevents-stenosis-of-tissue-engineered-vascular-grafts
#10
Juan de Dios Ruiz-Rosado, Yong-Ung Lee, Nathan Mahler, Tai Yi, Frank Robledo-Avila, Diana Martinez-Saucedo, Avione Y Lee, Toshihiro Shoji, Eric Heuer, Andrew R Yates, Jordan S Pober, Toshiharu Shinoka, Santiago Partida-Sanchez, Christopher K Breuer
We previously developed a tissue-engineered vascular graft (TEVG) made by seeding autologous cells onto a biodegradable tubular scaffold, in an attempt to create a living vascular graft with growth potential for use in children undergoing congenital heart surgery. Results of our clinical trial showed that the TEVG possesses growth capacity but that its widespread clinical use is not yet advisable due to the high incidence of TEVG stenosis. In animal models, TEVG stenosis is caused by increased monocytic cell recruitment and its classic ("M1") activation...
June 15, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/29905512/cranioplasty-with-a-low-cost-customized-polymethylmethacrylate-implant-using-a-desktop-3d-printer
#11
Jesús A Morales-Gómez, Everardo Garcia-Estrada, Jorge E Leos-Bortoni, Miriam Delgado-Brito, Luis E Flores-Huerta, Adriana A De La Cruz-Arriaga, Luis J Torres-Díaz, Ángel R Martínez-Ponce de León
OBJECTIVE Cranioplasty implants should be widely available, low in cost, and customized or easy to mold during surgery. Although autologous bone remains the first choice for repair, it cannot always be used due to infection, fragmentation, bone resorption, or other causes, which led to use of synthetic alternatives. The most frequently used allogenic material for cranial reconstructions with long-term results is polymethylmethacrylate (PMMA). Three-dimensional printing technology has allowed the production of increasingly popular customized, prefabricated implants...
June 15, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29905510/bleeding-risk-of-cerebral-cavernous-malformations-in-patients-on-%C3%AE-blocker-medication-a-cohort-study
#12
Johannes Goldberg, Christian Jaeggi, Daniel Schoeni, Pasquale Mordasini, Andreas Raabe, David Bervini
OBJECTIVE Cerebral cavernous malformations (CCMs) are frequently diagnosed vascular malformations of the brain. Although most CCMs are asymptomatic, some can be responsible for intracerebral hemorrhage or seizures. In selected cases, microsurgical resection is the preferred treatment option. Treatment with the unselective β-blocker propranolol has been presumed to stabilize and eventually lead to CCM size regression in a limited number of published case series; however, the underlying mechanism and evidence for this effect remain unclear...
June 15, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29904417/observation-of-corneal-transplantation-in-peripheral-corneal-disease-postoperatively
#13
Yibing Zhang, Yuan Hu, Xiaodong Li, Xiaoru Shi, Feihong Xu, Hui Jia
The aim of the present study was to investigate the role of the limbal stem cells in corneal epithelial homeostasis in patients with peripheral corneal disease who received corneal transplantation surgery. This retrospective study enrolled 85 patients (85 eyes) with peripheral corneal lesion who underwent corneal transplantation at Department of Ophthalmology in First Hospital of Jilin University, Jilin, China. All patients during each follow-up period were examined for best corrected visual acuity, corneal reconstruction (assessed by slit-lamp biomicroscopy), anterior segment optical coherence tomography, and confocal microscopy...
June 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29904248/devascularization-of-the-superior-mesenteric-vein-without-reconstruction-during-surgery-for-retroperitoneal-liposarcoma-a-case-report-and-review-of-literature
#14
Run-Chen Miao, Yong Wan, Xiao-Gang Zhang, Xing Zhang, Yan Deng, Chang Liu
A 61-year-old female patient with chronic hepatitis B virus infection was diagnosed with liposarcoma in a community hospital. Fine needle aspiration biopsy confirmed the diagnosis of well-differentiated liposarcoma. Abdominal computed tomographic angiography (CTA) showed that the mass adhered to and constricted the main trunk and branch of the superior mesenteric vein (SMV), especially the ileocolic vein, and collateral circulation was observed during the vascular reconstruction scan. The abdominal liposarcoma was resected...
June 14, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29903522/vascular-access-clinic-results-before-and-after-implementing-a-multidisciplinary-approach-adding-routine-doppler-ultrasound
#15
Inés Aragoncillo Sauco, José Manuel Ligero Ramos, Almudena Vega Martínez, Ángel Luis Morales Muñoz, Soraya Abad Estébanez, Nicolás Macías Carmona, Diego Ruiz Chiriboga, Rosario García Pajares, Teresa Cervera Bravo, Juan Manuel López-Gómez, Soledad Manzano Grossi, Elena Menéndez Sánchez, Javier Río Gomez, Ana María García Prieto, Tania Linares Grávalos, Fernando Garcia Boyano, Luis Manuel Reparaz Asensio, Marta Albalate Ramón, Patricia de Sequera Ortiz, Beatriz Gil Casares, Jara Ampuero Mencía, Sandra Castellano, Belén Martín Pérez, José Luís Martín Conty, Alba Santos Garcia, José Luño Fernandez
BACKGROUND: A multidisciplinary approach and Doppler ultrasound (DU) assessment for the creation and maintenance of arteriovenous fistulas (AVF) for haemodialysis can improve prevalence and patency. The aim of this study was to analyse the impact of a new multidisciplinary vascular access (VA) clinic with routine DU. MATERIAL AND METHODS: We analysed the VA clinic results from 2014 and 2015, before and after the implementation of a multidisciplinary team protocol (vascular surgeon/nephrologist) with routine DU in preoperative mapping and prevalent AVF...
June 11, 2018: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/29903509/the-impact-of-neutrophil-to-lymphocyte-ratio-and-platelet-to-lymphocyte-ratio-among-patients-with-intrahepatic-cholangiocarcinoma
#16
Stefan Buettner, Gaya Spolverato, Charles W Kimbrough, Sorin Alexandrescu, Hugo P Marques, Jorge Lamelas, Luca Aldrighetti, T Clark Gamblin, Shishir K Maithel, Carlo Pulitano, Matthew Weiss, Todd W Bauer, Feng Shen, George A Poultsides, J Wallis Marsh, Jan N M IJzermans, Bas Groot Koerkamp, Timothy M Pawlik
BACKGROUND: Neutrophil-to-lymphocyte ratio and platelets-to-lymphocyte ratio may be host factors associated with prognosis. We sought to determine whether neutrophil-to-lymphocyte and platelets-to-lymphocyte ratio were associated with overall survival among patients undergoing surgery for intrahepatic cholangiocarcinoma. METHODS: Patients who underwent resection for intrahepatic cholangiocarcinoma between 1990 and 2015 were identified from 12 major centers. Clinicopathologic factors and overall survival were compared among patients stratified by neutrophil-to-lymphocyte ratio and platelets-to-lymphocyte ratio...
June 11, 2018: Surgery
https://www.readbyqxmd.com/read/29903403/residual-pulmonary-hypertension-after-pulmonary-endarterectomy-a-meta-analysis
#17
Wan Chin Hsieh, Pavel Jansa, Wei Chun Huang, Matus Nižnanský, Mohamend Omara, Jaroslav Lindner
OBJECTIVE: Chronic thromboembolic pulmonary hypertension is surgically treated through pulmonary endarterectomy. Although pulmonary endarterectomy is the treatment of choice for chronic thromboembolic pulmonary hypertension in terms of both functional outcomes and survival, many patients experience persistent pulmonary hypertension after pulmonary endarterectomy. The study objective was to calculate the pooled estimates of outcomes after pulmonary endarterectomy, including persistent pulmonary hypertension...
May 17, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29902538/a-multicentre-observational-study-on-management-of-general-anaesthesia-in-elderly-patients-at-high-risk-of-postoperative-adverse-outcomes
#18
Serge Molliex, Sylvie Passot, Jerome Morel, Emmanuel Futier, Jean Yves Lefrant, Jean Michel Constantin, Yannick Le Manach, Bruno Pereira
INTRODUCTION: in elderly patients, goal directed haemodynamic therapy (GDHT), depth of anaesthesia monitoring and lung-protective ventilation have been shown to improve postoperative outcomes. The aim of this study was to evaluate current practices concerning strategies of anaesthesia optimisation in patients aged ≥ 75 years. PATIENTS AND METHODS: a multicentre observational study was performed from February to May 2015 in 23 French academic centres. On 30 consecutive days in each centre, patients ≥ 75 years with at least one major co-morbidity undergoing elective or emergency procedures (femoral-neck fractures surgery, intraperitoneal abdominal surgery or vascular surgery) were included...
June 11, 2018: Anaesthesia, Critical Care & Pain Medicine
https://www.readbyqxmd.com/read/29902388/phthisis-bulbi-a-clinicopathological-perspective
#19
Koushik Tripathy, Rohan Chawla, Shreyas Temkar, Pradeep Sagar, Seema Kashyap, Neelam Pushker, Yog Raj Sharma
Phthisis bulbi denotes end-stage eye disease characterized by shrinkage and disorganization of the eye with the resultant functional loss. The major factors associated with the pathogenesis of phthisis are hypotony, deranged blood-ocular barriers, and inflammation. Common causes include trauma, surgery, infection, inflammation, malignancy, retinal detachment, and vascular lesions. A phthisical globe shows a small squared off shape, opaque and thickened cornea, thickened sclera, neovascularization of iris, cataract, cyclitic membrane, ciliochoroidal detachment, and retinal detachment...
June 14, 2018: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/29902244/upregulation-of-krebs-cycle-and-anaerobic-glycolysis-activity-early-after-onset-of-liver-ischemia
#20
Tom S Chan, Shamir Cassim, Valérie-Ann Raymond, Sven Gottschalk, Grégory Merlen, Claudia Zwingmann, Pascal Lapierre, Peter Darby, Cyril David Mazer, Marc Bilodeau
The liver is a highly vascularized organ receiving a dual input of oxygenated blood from the hepatic artery and portal vein. The impact of decreased blood flow on glucose metabolism and how hepatocytes could adapt to this restrictive environment are still unclear. Using the left portal vein ligation (LPVL) rat model, we found that cellular injury was delayed after the onset of liver ischemia. We hypothesized that a metabolic adaptation by hepatocytes to maintain energy homeostasis could account for this lag phase...
2018: PloS One
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