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https://www.readbyqxmd.com/read/29055646/adolescent-access-to-information-on-contraceptives-a-mystery-client-study-in-mexico
#1
Filipa de Castro, Tonatiuh Barrientos-Gutierrez, Ariela Braverman-Bronstein, John Santelli, Jean Marie Place, Marcela Eternod-Arámburu, Mauricio Hernández-Avila
PURPOSE: We aimed to evaluate adolescent access to contraceptive information and quality of care in a sample of primary care clinics and pharmacies in Mexico and their association with health facility and adolescent characteristics. METHODS: We selected a random sample of pharmacies (n = 434) and public-sector, primary care clinics (n = 327) in Mexico City to be visited by young women posing as "mystery clients" looking for contraception or emergency contraception...
October 18, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29051734/overview-on-patient-centricity-in-cancer-care
#2
Šarunas Narbutas, Kristina York, Barry D Stein, Kara Magsanoc-Alikpala, Yoshiyuki Majima, Zoltan Kalo, Timea Almasi, Andras Inotai
Successful implementation of treatment in cancer care partially depends on how patients' perspectives are taken into account, as preferences of health care professionals and patients may differ. Objectives of this exploratory research were (I) to identify patient preferences and values (PPVs) in cancer care as indicated by patient organizations (POs), (II) to determine how these PPVs are captured in cancer care guidelines and (III) to review how guidelines take into account these PPVs. Based on a survey developed and completed by 19 POs, a literature review was conducted to analyse how patient perspectives are incorporated in oncology treatment guidelines...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29049049/treatable-traits-of-chronic-airways-disease
#3
James Fingleton, Jo Hardy, Richard Beasley
PURPOSE OF REVIEW: To describe the rationale on which the treatable traits approach to the management of airways disease is based and the issues that need to be considered for its implementation in clinical practice. RECENT FINDINGS: In clinical practice, treatable traits can be classified according to both endotypes and phenotypes, broadly grouped within pulmonary, extrapulmonary, environmental and behavioural factors. Specific investigations and treatments are undertaken for each of the traits rather than a 'one size fits all' stepwise approach to pharmacological treatment which currently represents the core of asthma and chronic obstructive pulmonary disease (COPD) guidelines...
October 18, 2017: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/29047361/cross-cultural-validation-of-simplified-chinese-version-of-spine-functional-index
#4
Xiao-Yi Zhou, Xi-Ming Xu, Jian-Ping Fan, Fei Wang, Sui-Yi Wu, Zi-Cheng Zhang, Yi-Lin Yang, Ming Li, Xian-Zhao Wei
BACKGROUND: No effective constructs were available in mainland China to assess the whole spine function. The SFI was developed to evaluate spinal function based on the concept of a single kinetic chain concept for whole spine. The SFI has been translated to Spanish and Turkish with accepted psychometric properties. It is imperative to introduce the SFI in mainland China and further to explore the measurement properties. METHODS: The English versions of the SFI was cross-culturally translated according to international guidelines...
October 18, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29044298/the-performance-of-crusade-and-acuity-bleeding-risk-scores-in-ticagrelor-treated-acs-patients-who-underwent-pci
#5
Shaozhi Xi, Shanshan Zhou, Xuyun Wang, Jia Liu, Liuan Qin, Jun Liu, Tong Yin, Yundai Chen
The performance of the CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA guidelines) and ACUITY (Acute Catheterization and Urgent Intervention Triage strategy) risk scores for the prediction of major bleeding in ticagrelor-treated acute coronary syndrome (ACS) patients who underwent percutaneous coronary intervention (PCI) is unknown. The aim of the present study is to validate the performance of both scores in a contemporary Chinese cohort of ACS patients hospitalized for PCI and administrated with ticagrelor...
October 10, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/29038268/urinary-tract-conditions-affect-fosfomycin-activity-against-escherichia-coli-strains-harboring-chromosomal-mutations-involved-in-fosfomycin-uptake
#6
G Martín-Gutiérrez, F Docobo-Pérez, J Rodriguez-Beltrán, J M Rodríguez-Martínez, J Aznar, A Pascual, J Blázquez
The steps by which Escherichia coli strains harboring mutations related with fosfomycin (FOS) resistance arise and spread during urinary tract infections (UTI) is far to be understood. The aim of this study was to evaluate the effect of urine, pH and anaerobiosis on FOS activity against a set of isogenic strains carrying the most prevalent chromosomal mutations conferring FOS-resistance (ΔuhpT, ΔglpT, ΔcyaA and ΔptsI) and their combinations. Also, fosfomycin resistant E. coli clinical isolates from patients with UTI were studied...
October 16, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29036509/medication-usage-change-in-older-people-65-in-england-over-20-years-findings-from-cfas-i-and-cfas-ii
#7
L Gao, Ian Maidment, Fiona E Matthews, Louise Robinson, Carol Brayne
Background: medical practice has changed over the last decades reflecting the ageing population, when multi-morbidity requiring multiple medications is more common. Objective: describe and quantify self-reported medicine use including both prescription and over the counter medicines in two comparable population-based studies of older people (65+) in England and to assess the nature and scale of polypharmacy. Methods: data used were from two separate population-based studies; the Cognitive Function Ageing Study I and II...
September 26, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29036276/multimorbidity-will-it-stand-the-test-of-time
#8
Joanna C Ford, John A Ford
The concept of multimorbidity has risen in popularity over the past few years. It is use has led to, or coincided with, an increased recognition that patients often have more than one health problem which should not be treated in isolation. The motivation for more holistic, person-centred care that lies behind multimorbidity is to be welcomed. The 2016 National Institute for Health and Care Excellence multimorbidity management guideline helpfully makes recommendations in key areas that are important in the care of patients with complicated medical problems...
September 26, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29036032/a-physiological-profile-of-ovarian-cancer-survivors-to-inform-tailored-exercise-interventions-and-the-development-of-exercise-oncology-guidelines
#9
Christelle Schofield, Robert U Newton, Daniel A Galvão, Paul A Cohen, Carolyn J Peddle-McIntyre
OBJECTIVE: Physical activity has become increasingly important in supportive cancer care. However, physical activity and exercise guidelines for ovarian cancer survivors remain generic. The aim of this narrative review is to summarize existing data regarding the physiological characteristics (treatment-related adverse effects, concurrent comorbidities, body weight and composition, physical fitness and function, and physical activity behavior) of ovarian cancer survivors to further understanding of their cancer-specific physical activity and exercise needs...
September 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29025132/most-relevant-neuropathic-pain-treatment-and-chronic-low-back-pain-management-guidelines-a-change-pain-latin-america-advisory-panel-consensus
#10
Cesar Amescua-Garcia, Frantz Colimon, Carlos Guerrero, Aziza Jreige Iskandar, Maria Berenguel Cook, Patricia Bonilla, Durval Campos Kraychete, William Delgado Barrera, Jose Alberto Flores Cantisani, John Jairo Hernandez-Castro, Argelia Lara-Solares, Concepcion Perez Hernandez, Maria Antonieta Rico, Maria Del Rocio Guillen Nunez, Manuel Sempertegui Gallegos, Joao Batista Santos Garcia
Objective: Chronic pain conditions profoundly affect the daily living of a significant number of people and are a major economic and social burden, particularly in developing countries. The Change Pain Latin America (CPLA) advisory panel aimed to identify the most appropriate guidelines for the treatment of neuropathic pain (NP) and chronic low back pain (CLBP) for use across Latin America. Methods: Published systematic reviews or practice guidelines were identified by a systematic search of PubMed, the Guidelines Clearinghouse, and Google...
August 24, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29022408/screening-of-colorectal-cancer-present-and-future
#11
Marcello Maida, Fabio Salvatore Macaluso, Gianluca Ianiro, Francesca Mangiola, Emanuele Sinagra, Georgina Hold, Carlo Maida, Giovanni Cammarota, Antonio Gasbarrini, Giuseppe Scarpulla
Colorectal cancer (CRC) is the third most common cancer in males and second in females, and the fourth most common cause of cancer death worldwide. Currently, about 60-70% of diagnosed cases in symptomatic patients are detected at an advanced stage of disease. Earlier stage detection through the use of screening strategies would allow for better outcomes in terms of reducing the disease burden. Areas covered: The aim of this paper is to review the current published evidence from literature which assesses the performance and effectiveness of different screening tests for the early detection of CRC...
October 12, 2017: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/29017991/feasibility-of-gamified-mobile-service-aimed-at-physical-activation-in-young-men-population-based-randomized-controlled-study-mopo
#12
Anna-Maiju Leinonen, Riitta Pyky, Riikka Ahola, Maarit Kangas, Pekka Siirtola, Tim Luoto, Heidi Enwald, Tiina M Ikäheimo, Juha Röning, Sirkka Keinänen-Kiukaanniemi, Matti Mäntysaari, Raija Korpelainen, Timo Jämsä
BACKGROUND: The majority of young people do not meet the recommendations on physical activity for health. New innovative ways to motivate young people to adopt a physically active lifestyle are needed. OBJECTIVE: The study aimed to study the feasibility of an automated, gamified, tailored Web-based mobile service aimed at physical and social activation among young men. METHODS: A population-based sample of 496 young men (mean age 17.8 years [standard deviation 0...
October 10, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29016957/case-specific-colleague-guidance-for-general-practitioners-management-of-sickness-absence
#13
H P Nordhagen, S B Harvey, E O Rosvold, D Bruusgaard, R Blonk, A Mykletun
Background: General practitioners (GPs) report sickness absence certification as challenging. They express need for support with functional assessment beyond guidelines and reforms. Case-specific collegial one-to-one guidance for other clinical topics has proved popular with GPs and may be an acceptable and effective way to improve GPs skills and competence in sickness absence certification. Aims: To present a new model of case-specific colleague guidance focusing on the management of long-term sickness absence and to describe its feasibility in terms of application and reception among GPs, and also GPs' self-reports of effects on their practice...
August 24, 2017: Occupational Medicine
https://www.readbyqxmd.com/read/29016251/addressing-the-problem-of-obesity-and-associated-cardiometabolic-risk-in-black-south-african-women-time-for-action
#14
Julia H Goedecke
The PhD thesis of Gradidge, entitled 'Factors associated with obesity and metabolic syndrome in an ageing cohort of black women living in Soweto, Johannesburg (Study of Women in and Entering Endocrine Transition [SWEET])', attempts to understand the determinants of obesity and metabolic syndrome (MetS) in a population of urban-dwelling black South African women. A conceptual framework is presented, which positions obesity as the central risk factor for MetS, and includes the possible influence of socioeconomic status, lifestyle behaviours and body size perceptions, as key determinants of obesity...
2017: Global Health Action
https://www.readbyqxmd.com/read/28994889/heart-rate-beat-to-beat-slope-change-during-six-minute-walk-test-a-useful-clinical-tool-for-estimating-fitness-level
#15
Abdulrahman Mohammed Alhowikan, Abdullah Alfaifi, Badr Almutairi, Omar Alzamil, Muath Aleid
BACKGROUND: The six-minute walk test (6MWT) is one of the most common exercise tests and is used to estimate the level of physical fitness. This study aimed to evaluate the feasibility of the beat-to-beat heart rate 6MWT slope (6MWTS) and recovery slope for predicting and estimating the level of physical fitness during 6MWT, instead of depending on the distance covered during the test. METHODS: Seventy healthy adult male subjects aged 18 to 27 years were recruited randomly from the general Saudi population in Riyadh...
December 2016: La Tunisie Médicale
https://www.readbyqxmd.com/read/28989095/risk-factors-and-prevention-of-hepatocellular-carcinoma-in-the-era-of-precision-medicine
#16
REVIEW
Naoto Fujiwara, Scott L Friedman, Nicolas Goossens, Yujin Hoshida
Chronic fibrotic liver disease caused by viral or metabolic etiologies is a high-risk condition for developing hepatocellular carcinoma (HCC). Even after complete HCC tumor resection or ablation, the carcinogenic tissue microenvironment in the remnant liver can give rise to recurrent de novo HCC tumors, which progress into incurable, advanced-stage disease in the majority of patients. Thus, early detection and prevention of HCC development is, in principle, the most impactful strategy to improve patient prognosis...
October 5, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28986292/validation-of-an-indirect-elisa-employing-a-chimeric-recombinant-gag-and-env-peptide-for-the-serological-diagnosis-of-equine-infectious-anemia
#17
Maria Teresa Scicluna, Gian Luca Autorino, Chiara Nogarol, Ida Ricci, Raffaele Frontoso, Francesca Rosone, Roberto Nardini
The National Reference Center for equine infectious anemia (EIA) validated a commercial ELISA (Eradikit(®) EIAV Indirect ELISA, In3diagnostic(®), Turin, Italy) employing a chimeric recombinant gag and env peptide for the detection of EIA virus antibodies, following the guidelines of the World Organization for Animal Health. The validation parameters evaluated were: analytical sensitivity (Se) and specificity (Sp); diagnostic Se and Sp; precision, based on repeatability and reproducibility through the estimation of the standard deviation (SD) and the coefficient of variation (CV); accuracy, estimated from a multiple K and relative Sp and Se with respect to those of the agar gel immunodiffusion test (AGIDT)...
October 3, 2017: Journal of Virological Methods
https://www.readbyqxmd.com/read/28984499/the-assessment-of-mindfulness-skills-the-what-and-the-how
#18
Luca Iani, Marco Lauriola, Valentina Cafaro
BACKGROUND: The five facets mindfulness questionnaire-short form (FFMQ-SF) is a new, brief measure for the assessment of mindfulness skills in clinical and nonclinical samples. The construct validity of the FFMQ-SF has not been previously assessed in community samples. AIMS: The present study investigated the factor structure of the Italian version of the FFMQ-SF. METHOD: Structured equation modeling was used to test the fit of three alternative models in a sample of highly educated adults (n = 211)...
October 6, 2017: Journal of Mental Health
https://www.readbyqxmd.com/read/28983881/alzheimer-s-disease-and-driving-review-of-the-literature-and-consensus-guideline-from-belgian-dementia-experts-and-the-belgian-road-safety-institute-endorsed-by-the-belgian-medical-association
#19
Jan Versijpt, Mark Tant, Ingo Beyer, Jean-Christophe Bier, Patrick Cras, Peter P De Deyn, Patrick De Wit, Olivier Deryck, Bernard Hanseeuw, Margareta Lambert, Jean-Claude Lemper, Eric Mormont, Mirko Petrovic, Gaetane Picard, Eric Salmon, Kurt Segers, Anne Sieben, Evert Thiery, Jos Tournoy, Maurits Vandewoude, Manfredi Ventura, Jurn Verschraegen, Sebastiaan Engelborghs, Tom Goffin, Michel Deneyer, Adrian Ivanoiu
Alzheimer's disease (AD) is a highly prevalent condition and its prevalence is expected to further increase due to the aging of the general population. It is obvious that the diagnosis of AD has implications for driving. Finally, driving discussions are also emotionally charged because driving is associated with independence and personal identity. However, it is not clear how to implement this in clinical practice and the Belgian law on driving is rather vague in its referral to neurodegenerative brain diseases in general nor does it provide clear-cut instructions for dementia or AD compared to for example driving for patients with epilepsy and as such does not prove to be very helpful...
October 5, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/28977411/alcohol-consumption-and-risk-of-common-cancers-evidence-from-a-cohort-of-adults-from-the-uk
#20
Georgina Betts, Elena Ratschen, Magdalena Opazo Breton, Matthew J Grainge
Background: Recent guidelines from the UK recommend that men and women should drink no more than 14 units of alcohol per week. This recommendation takes into account the link between alcohol and several cancers; however, there is a dearth of high quality evidence from the UK to support this. Methods: Alcohol consumption using a detailed diary was obtained from 8670 adults representative of the UK population in 1984/5, with follow-up data from cancer registries until 2009...
September 11, 2017: Journal of Public Health
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