keyword
MENU ▼
Read by QxMD icon Read
search

running guidelines

keyword
https://www.readbyqxmd.com/read/28098395/first-uhplc-ms-ms-method-coupled-with-automated-on-line-spe-for-quantification-both-of-tacrolimus-and-everolimus-in-peripheral-blood-mononuclear-cells-and-its-application-on-samples-from-co-treated-pediatric-patients
#1
Debora Pensi, Amedeo De Nicolò, Michele Pinon, Clarissa Pisciotta, Pier Luigi Calvo, Antonello Nonnato, Renato Romagnoli, Francesco Tandoi, Giovanni Di Perri, Antonio D'Avolio
Tacrolimus (TAC, FK-506) and everolimus (EVE, RAD001) are immunosuppressors used to treat pediatric patients undergoing liver transplantation. Their hematic TDM by liquid chromatography became standard practice. However, it does not always reflect concentrations at their active site. Our aim was to develop and validate a new method for the simultaneous TAC and EVE quantification into target cells: Peripheral-Blood-Mononuclear-Cells (PBMCs). PBMCs were collected using Cell-Preparation-Tubes; cells number and MCV were evaluated by an automatic cell counter...
January 18, 2017: Journal of Mass Spectrometry: JMS
https://www.readbyqxmd.com/read/28098262/quantification-of-the-sources-and-composition-of-particulate-matter-by-field-deployable-mass-spectrometry-implications-for-air-quality-and-public-health
#2
Patrick L Hayes
Airborne particulate matter less than 2.5 μm in diameter (PM2.5) negatively impacts air quality in cities throughout the world where it has been linked to increased cardiac and respiratory morbidity and mortality. For this reason PM2.5 standards have been established by many countries and the World Health Organization. However, these guidelines are regularly exceeded in North America, Europe and East Asia. While PM2.5 is often reported as a single atmospheric species, it is actually a mixture of organic and inorganic compounds...
January 18, 2017: Analyst
https://www.readbyqxmd.com/read/28090477/the-economic-cost-of-implementing-maternal-and-neonatal-death-review-in-a-district-of-bangladesh
#3
Animesh Biswas, Abdul Halim, Fazlur Rahman, Charli Eriksson, Koustuv Dalal
INTRODUCTION: Maternal and neonatal death review (MNDR) introduced in Bangladesh and initially piloted in a district during 2010. MNDR is able to capture each of the maternal, neonatal deaths and stillbirths from the community and government facilities (hospitals). This study aimed to estimate the cost required to implement MNDR in a district of Bangladesh during 2010-2012. MATERIALS AND METHODS: MNDR was implemented in Thakurgaon district in 2010 and later gradually extended until 2015...
December 9, 2016: Journal of Public Health Research
https://www.readbyqxmd.com/read/28077751/performance-of-health-workers-using-an-electronic-algorithm-for-the-management-of-childhood-illness-in-tanzania-a-pilot-implementation-study
#4
Clotilde Rambaud-Althaus, Amani Shao, Josephine Samaka, Ndeniria Swai, Seneca Perri, Judith Kahama-Maro, Marc Mitchell, Valérie D'Acremont, Blaise Genton
In low-resource settings, where qualified health workers (HWs) are scarce and childhood mortality high, rational antimicrobial prescription for childhood illnesses is a challenge. To assess whether smartphones running guidelines, as compared with paper support, improve consultation process and rational use of medicines for children, a pilot cluster-randomized controlled study was conducted in Tanzania. Nine primary health-care facilities (HFs) were randomized into three arms: 1) paper algorithm, 2) electronic algorithm on a smartphone, and 3) control...
January 11, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28069690/development-of-solid-phase-extraction-and-hplc-method-for-simultaneous-estimation-of-ilaprazole-and-glimepiride-in-rat-plasma-application-to-pharmacokinetic-studies
#5
A P Dewani, A S Tripathi, P G Shelke, R L Bakal, D S Mohale, A V Chandewar
A novel, simple and mass spectrometry (MS) compatible high-performance liquid chromatography (HPLC) method is reported for the simultaneous estimation of ilaprazole (ILA) and glimepiride (GLM) in rat plasma. The bio-analytical procedure involves extraction of ILA, GLM and internal standard (IS) from rat plasma with a solid-phase extraction (SPE) process. The chromatographic analysis was performed on Waters-600 system using an isocratic mobile phase comprising methanol:water (80:20 % v/v) with pH of water modified to three using formic acid at a flow rate of 1...
January 8, 2017: Journal of Chromatographic Science
https://www.readbyqxmd.com/read/28047662/su-f-t-537-prone-breast-accelerated-partial-breast-irradiation-using-non-coplanar-volumetric-arc-therapy
#6
G Beninati, J Barbiere, L Godfrey, A Ndlovu
PURPOSE: To demonstrate that Volumetric Modulated Arc Therapy (VMAT) can be an alternative technique to Brachytherapy Accelerated Partial Breast Irradiation (APBI) for treating large breasted women. The non-coplanar VMAT technique uses a commercially available couch and a small number of angles. This technique with the patient in the prone position can reduce high skin and critical structure doses in large breasted women, which are usually associated with Brachytherapy APBI. METHODS: Philips Pinnacle treatment planning system with Smart Arc was used to plan a left sided laterally located excision cavity on a standard prone breast patient setup...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046601/su-f-t-232-monthly-quality-assurance-in-external-beam-radiation-therapy-using-a-single-system
#7
K Ding, T Ji, I Iordachita, E Velarde, J Hyatt, J Wong
PURPOSE: Monthly quality assurance (QA) is time consuming for external beam radiation therapy, taking as long as 6-8 hours for each machine. It is due to the use and setup of multiple devices for different QA procedures. We have developed a single system with rotational capability for the measurement of both optical light and radiation which significantly reduces the time spent on Monthly QA. METHODS: A single system using mirrors, a phosphor screen and a CCD camera is housed on a cylindrical motor so that it can rotate 360 degrees...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045979/intensive-patient-education-improves-glycaemic-control-in-diabetes-compared-to-conventional-education-a-randomised-controlled-trial-in-a-nigerian-tertiary-care-hospital
#8
Okon Essien, Akaninyene Otu, Victor Umoh, Ofem Enang, Joseph Paul Hicks, John Walley
BACKGROUND: Diabetes is now a global epidemic, but most cases are now in low- and middle-income countries. Diabetes self-management education (DSME) is key to enabling patients to manage their chronic condition and can reduce the occurrence of costly and devastating complications. However, there is limited evidence on the effectiveness of different DSME programmes in resource limited settings. METHODS: We conducted an unblinded, parallel-group, individually-randomised controlled trial at the University of Calabar Teaching Hospital (Nigeria) to evaluate whether an intensive and systematic DSME programme, using structured guidelines, improved glycaemic control compared to the existing ad hoc patient education (clinical practice was unchanged)...
2017: PloS One
https://www.readbyqxmd.com/read/28040586/simultaneous-arsenic-and-fluoride-removal-from-synthetic-and-real-groundwater-by-electrocoagulation-process-parametric-and-cost-evaluation
#9
Lokendra Singh Thakur, Prasenjit Mondal
Co-existence of arsenic and fluoride in groundwater has raised severe health issues to living being. Thus, the present research has been conducted for simultaneous removal of arsenic and fluoride from synthetic groundwater by using electrocoagulation process with aluminum electrode. Effects of initial pH, current density, run time, inter electrode distance and NaCl concentration over percentage removal of arsenic and fluoride as well as operating cost have been studied. The optimum experimental conditions are found to be initial pH: 7, current density: 10 A/m(2), run time: 95 min, inter electrode distance: 1 cm, NaCl concentration: 0...
December 29, 2016: Journal of Environmental Management
https://www.readbyqxmd.com/read/28007583/towards-a-privacy-preserving-cohort-discovery-framework-for-clinical-research-networks
#10
Jiawei Yuan, Bradley Malin, François Modave, Yi Guo, William R Hogan, Elizabeth Shenkman, Jiang Bian
BACKGROUND: The last few years have witnessed an increasing number of clinical research networks (CRNs) focused on building large collections of data from electronic health records (EHRs), claims, and patient-reported outcomes (PROs). Many of these CRNs provide a service for the discovery of research cohorts with various health conditions, which is especially useful for rare diseases. Supporting patient privacy can enhance the scalability and efficiency of such processes; however, current practice mainly relies on policy, such as guidelines defined in the Health Insurance Portability and Accountability Act (HIPAA), which are insufficient for CRNs (e...
December 19, 2016: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28007331/combination-therapy-of-rosuvastatin-and-ezetimibe-in-patients-with-high-cardiovascular-risk
#11
Young-June Yang, Sang-Hak Lee, Byung Soo Kim, Yun-Kyeong Cho, Hyun-Jai Cho, Kyoung Im Cho, Seok-Yeon Kim, Jae Kean Ryu, Jin-Man Cho, Joong-Il Park, Jong-Seon Park, Chang Gyu Park, Woo Jung Chun, Myung-A Kim, Dong-Kyu Jin, Namho Lee, Byung Jin Kim, Kwang Kon Koh, Jon Suh, Seung-Hwan Lee, Byoung-Kwon Lee, Seung-Jin Oh, Han-Young Jin, Youngkeun Ahn, Sang-Gon Lee, Jang-Ho Bae, Woo Jung Park, Sang-Chol Lee, Han Cheol Lee, Jaewon Lee, Cheolwon Park, Backhwan Lee, Yangsoo Jang
PURPOSE: The aim of this study was to evaluate the efficacy and tolerability of rosuvastatin/ezetimibe combination therapy in Korean patients with high cardiovascular risk. METHODS: This was a 12-week, randomized, double-blind, placebo-controlled, multicenter study. A total of 337 patients were screened. After a 4-week run-in period, 245 of these patients with high or moderately high risk as defined by the National Cholesterol Education Program Adult Treatment Panel III guidelines were randomly assigned...
December 19, 2016: Clinical Therapeutics
https://www.readbyqxmd.com/read/28006653/evaluation-of-molecular-typing-of-foodborne-pathogens-in-european-reference-laboratories-from-2012-to-2013
#12
Susanne Schjørring, Taina Niskanen, Mia Torpdahl, Jonas T Björkman, Eva Møller Nielsen
In 2012, the European Centre for Disease Prevention and Control (ECDC) initiated external quality assessment (EQA) schemes for molecular typing including the National Public Health Reference Laboratories in Europe. The overall aim for these EQA schemes was to enhance the European surveillance of food-borne pathogens by evaluating and improving the quality and comparability of molecular typing. The EQAs were organised by Statens Serum Institut (SSI) and included Salmonella enterica subsp. enterica, verocytotoxin-producing Escherichia coli (VTEC) and Listeria monocytogenes...
December 15, 2016: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28003026/a-nurse-led-clinic-for-patients-consulting-with-osteoarthritis-in-general-practice-development-and-impact-of-training-in-a-cluster-randomised-controlled-trial
#13
Emma L Healey, Chris J Main, Sarah Ryan, Gretl A McHugh, Mark Porcheret, Andrew G Finney, Andrew Morden, Krysia S Dziedzic
BACKGROUND: Despite a lack of service provision for people with osteoarthritis (OA), each year 1 in 5 of the general population consults a GP about a musculoskeletal condition such as OA. Consequently this may provide an opportunity for practice nurses to take an active role in helping patients manage their condition. A nurse led clinic for supporting patients with OA was developed for the MOSAICS study investigating how to implement the NICE 2014 OA Guideline core recommendations. This paper has two main objectives, firstly to provide an overview of the nurse-led OA clinic, and secondly to describe the development, key learning objectives, content and impact of the training to support its delivery...
December 21, 2016: BMC Family Practice
https://www.readbyqxmd.com/read/28001405/development-of-site-specific-mg-2-rna-force-field-parameters-a-dream-or-reality-guidelines-from-combined-molecular-dynamics-and-quantum-mechanics-simulations
#14
Lorenzo Casalino, Giulia Palermo, Nodira Abdurakhmonova, Ursula Rothlisberger, Alessandra Magistrato
The vital contribution of Mg(2+) ions to RNA biology is challenging to dissect at the experimental level. This calls for the integrative support of atomistic simulations, which at the classical level are plagued by limited accuracy. Indeed, force fields intrinsically neglect nontrivial electronic effects that Mg(2+) exerts on its surrounding ligands in varying RNA coordination environments. Here, we present a combined computational study based on classical molecular dynamics (MD) and Density Functional Theory (DFT) calculations, aimed at characterizing (i) the performance of five Mg(2+) force field (FF) models in RNA systems and (ii) how charge transfer and polarization affect the binding of Mg(2+) ions in different coordination motifs...
December 21, 2016: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/27990224/the-relationship-between-aerobic-and-anaerobic-performance-in-recreational-runners
#15
Zachary M Gillen, Frank B Wyatt, Jason B Winchester, Dalton A Smith, Vidhi Ghetia
Research has indicated that combined aerobic and anaerobic training (concurrent training) may improve aerobic performance greater than aerobic training alone. The purpose of this investigation was to establish any associations between aerobic and anaerobic performance. Eleven participants (n = 11, age = 34.1 ± 13 years, VO2max = 58.4 ± 7.8) volunteered for this study. Participants were asked for endurance training experience (4.7 ± 3.7 years) and resistance training experience (4.1 ± 4.6 years). To meet training status, participants were to have a VO2max in the 80(th) percentile as per ACSM guidelines...
2016: International Journal of Exercise Science
https://www.readbyqxmd.com/read/27989489/testosterone-pellet-implantation-practices-a-sexual-medicine-society-of-north-america-smsna-member-questionnaire
#16
Michael J Piecuch, Brijesh G Patel, Lawrence Hakim, Run Wang, Hossein Sadeghi-Nejad
INTRODUCTION: There has been renewed interest in the use of subcutaneous testosterone pellets for the treatment of hypogonadism since the introduction of Testopel in 2008 by Slate Pharmaceuticals (Durham, NC, USA). Manufacturer guidelines recommend using two to six pellets; however, in the clinical setting, this is deemed insufficient. This has produced a wide variety of testosterone pellet usage that is not fully understood. AIM: To better understand subcutaneous testosterone pellet implantation practices among members of the Sexual Medicine Society of North America (SMSNA)...
December 15, 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27955976/latent-class-analysis-an-example-for-reporting-results
#17
James B Schreiber
The purpose of this paper is to provide a brief non-mathematical introduction to Latent Class Analysis (LCA) and a demonstration for researchers new to the analysis technique in pharmacy and pharmacy administration. LCA is a mathematical technique for examining relationships among observed variables when there may be collections of unobserved categorical variables. Traditionally, LCA focused on polytomous observed variables, but recent work has extended the types of data that can be utilized. Included in this introduction are basic guidelines for the information that should be part of a manuscript submitted for review...
November 30, 2016: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/27940626/pay-more-attention-a-national-mixed-methods-study-to-identify-the-barriers-and-facilitators-to-ensuring-equal-access-to-high-quality-hospital-care-and-services-for-children-and-young-people-with-and-without-learning-disabilities-and-their-families
#18
Kate Oulton, Jo Wray, Lucinda Carr, Angela Hassiotis, Carey Jewitt, Sam Kerry, Irene Tuffrey-Wijne, Faith Gibson
INTRODUCTION: Despite evidence of health inequalities for adults with intellectual disability (ID) there has yet to be a comprehensive review of how well hospital services are meeting the needs of children and young people (CYP) with ID and their families. We do not know how relevant existing recommendations and guidelines are to CYP, whether these are being applied in the paediatric setting or what difference they are making. Evidence of parental dissatisfaction with the quality, safety and accessibility of hospital care for CYP with ID exists...
December 9, 2016: BMJ Open
https://www.readbyqxmd.com/read/27931205/assessment-of-near-visual-acuity-in-0-13-year-olds-with-normal-and-low-vision-a-systematic-review
#19
Bianca Huurneman, F Nienke Boonstra
BACKGROUND: The inclusion for rehabilitation of visually impaired children is partly based on the measurement of near vision, but guidelines for near visual acuity assessment are currently lacking. The twofold purpose of this systematic review was to: (i) provide an overview of the impact of the chart design on near visual acuity measured, and (ii) determine the method of choice for near vision assessments in children of different developmental ages. METHODS: A literature search was conducted by using the following electronic databases: PubMed, Cochrane Library, and EMBASE...
December 8, 2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27930803/pulmonary-rehabilitation-following-exacerbations-of-chronic-obstructive-pulmonary-disease
#20
REVIEW
Milo A Puhan, Elena Gimeno-Santos, Christopher J Cates, Thierry Troosters
BACKGROUND: Guidelines have provided positive recommendations for pulmonary rehabilitation after exacerbations of chronic obstructive pulmonary disease (COPD), but recent studies indicate that postexacerbation rehabilitation may not always be effective in patients with unstable COPD. OBJECTIVES: To assess effects of pulmonary rehabilitation after COPD exacerbations on hospital admissions (primary outcome) and other patient-important outcomes (mortality, health-related quality of life (HRQL) and exercise capacity)...
8, 2016: Cochrane Database of Systematic Reviews
keyword
keyword
75490
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"