Yu Horiuchi, Nicholas Wettersten, Dirk J van Veldhuisen, Christian Mueller, Richard Nowak, Christopher Hogan, Michael C Kontos, Chad M Cannon, Robert Birkhahn, Gary M Vilke, Niall Mahon, Julio Nuñez, Carlo Briguori, Stephen Duff, Patrick T Murray, Alan Maisel
BACKGROUND: Body mass index (BMI) is a known confounder for natriuretic peptides but its influence on other biomarkers is less well described. We investigated whether BMI interacts with biomarkers association with prognosis in patients with acute heart failure (AHF). METHODS AND RESULTS: B-type natriuretic peptide (BNP), high-sensitivity cardiac troponin I (hs-cTnI), galectin-3, serum neutrophil gelatinase associated lipocalin (sNGAL) and urine NGAL were measured serially in AHF patients during hospitalization in the AKINESIS study...
April 29, 2023: Journal of Cardiac Failure