keyword
https://read.qxmd.com/read/38546282/paediatric-endoscopic-endonasal-middle-skull-base-reconstruction-retrospective-analysis-of-78-patients-treated-in-a-single-tertiary-care-paediatric-center
#1
JOURNAL ARTICLE
Danilo Di Giorgio, Filippo Giovannetti, Paolo Priore, Mirko Scagnet, Federico Mussa, Ingrid Raponi, Valentino Valentini, Lorenzo Genitori
INTRODUCTION: Skull base pathologies in the paediatric population are rare and require treatment by multiple qualified specialists. The endoscopic endonasal approach has revolutionized surgical treatment because it is less invasive than existing treatments.The goal of this study was to retrospectively review our experience with the reconstruction of paediatric skull middle base defects and associated complications. MATERIALS AND METHODS: We analysed medical records from patients aged ≤ 18 years who were treated at our centre between 2013 and 2021...
March 28, 2024: British Journal of Neurosurgery
https://read.qxmd.com/read/38538470/diagnosis-and-management-of-congenital-hypopituitarism-in-children
#2
Sarah Castets, Cécile Thomas-Teinturier, Carine Villanueva, Jessica Amsellem, Pascal Barat, Gilles Brun, Emmanuel Bui Quoc, Jean-Claude Carel, Gian Paolo De Filippo, Clara Kipnis, Laetitia Martinerie, Julia Vergier, Alexandru Saveanu, Natacha Teissier, Régis Coutant, Juliane Léger, Rachel Reynaud
Hypopituitarism (or pituitary deficiency) is a rare disease with an estimated prevalence of between 1/16,000 and 1/26,000 individuals, defined by insufficient production of one or several anterior pituitary hormones (growth hormone [GH], thyroid-stimulating hormone [TSH], adrenocorticotropic hormone [ACTH], luteinizing hormone [LH], follicle-stimulating hormone [FSH], prolactin), in association or not with diabetes insipidus (antidiuretic hormone [ADH] deficiency). While in adults hypopituitarism is mostly an acquired disease (tumors, irradiation), in children it is most often a congenital condition, due to abnormal pituitary development...
March 26, 2024: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://read.qxmd.com/read/38531471/a-simple-scoring-system-for-predicting-the-risk-of-delayed-hyponatremia-after-endoscopic-transsphenoidal-surgery-for-pituitary-adenomas
#3
JOURNAL ARTICLE
Changhong Mo, Maoxiang Li, Yangyang Li, Yi Liu, Ruijing Zhao, Hao Wang, Jiliang Hu, Wei Guo
BACKGROUNDS: To identify high-risk patients for delayed postoperative hyponatremia (DPH) early, we constructed a simple and effective scoring system. METHODS: We retrospectively analyzed 141 consecutive patients who underwent endoscopic transsphenoidal surgery (TSS) from January 2019 to December 2022. Patients were divided into DPH group and non-DPH (NDPH) group based on whether hyponatremia occurred after the third postoperative day. Multivariable logistic regression analysis was conducted to determine the predictive factors of DPH, and a simple scoring system was constructed based on these predictors...
March 24, 2024: World Neurosurgery
https://read.qxmd.com/read/38529718/a-case-of-pregnancy-with-severe-polyhydramnios-related-to-long-term-use-of-lithium
#4
JOURNAL ARTICLE
Aldo Stoppa, Ester Roda, Lluïsa Garcia-Esteve, Alba Roca-Lecumberri
OBJECTIVES: Severe polyhydramnios during pregnancy may be associated with long-term lithium use and presents considerable challenges. This complication, which has been linked to induced nephrogenic diabetes insipidus (NDI), underscores the necessity for cautious management of pregnant women with bipolar disorder. This case report aims to elucidate the relationship between long-term lithium use, pregnancy, and the development of severe polyhydramnios, emphasizing the importance of diagnosing NDI in order to prevent obstetric and neonatal complications...
March 26, 2024: Bipolar Disorders
https://read.qxmd.com/read/38502003/persistent-hypernatremia-secondary-to-adipsic-central-diabetes-insipidus-in-a-patient-with-herpes-induced-meningoencephalitis-and-covid-19-infection-a-case-report
#5
JOURNAL ARTICLE
Faten Cherchir, Ibtissem Oueslati, Salma Salhi, Asma Ben Hamida, Meriem Yazidi, Melika Chihaoui
Central diabetes insipidus (CDI) typically manifests as a polyuria-polydipsia syndrome, in which normonatremia is generally maintained through the polydipsia. A 53-year-old woman presented with diabetic ketosis and hyperosmolar hyperglycemic syndrome. Her medical history included herpes meningoencephalitis, which was associated with confusion and amnesia. On physical examination, she was apyretic, confused, and had signs of extracellular dehydration. Her capillary glucose concentration was high and her urine was positive for ketones...
March 2024: Journal of International Medical Research
https://read.qxmd.com/read/38497187/effect-of-resection-and-surgical-experience-on-survival-in-patients-with-craniopharyngiomas-endoscopic-transsphenoidal-surgery-in-series-of-31-cases
#6
JOURNAL ARTICLE
Buruc Erkan, Ozan Barut, Ebubekir Akpinar, Mehmet Sait Cil, Suat Demir, Yusuf Kilic, Osman Tanriverdi, Esra Suheda Hatipoglu, Omur Gunaldi
AIM: To share the surgical outcomes of 31 patients who underwent endoscopic endonasal transsphenoidal surgery (EETS) at a single center. MATERIAL AND METHODS: This retrospective analysis of 31 craniopharyngioma cases (2013-2022) with a minimum 6-month follow-up included demographic data, preoperative findings, postoperative resection volumes, recurrence rates, pathological diagnoses, and complications. RESULTS: Herein, 34 EETS surgeries were performed on 31 patients (12 males, 19 females)...
2024: Turkish Neurosurgery
https://read.qxmd.com/read/38488559/growth-hormone-promotes-the-reconstruction-of-injured-axons-in-the-hypothalamo-neurohypophyseal-system
#7
JOURNAL ARTICLE
Kai Li, Zhanpeng Feng, Zhiwei Xiong, Jun Pan, Mingfeng Zhou, Weizhao Li, Yichao Ou, Guangsen Wu, Mengjie Che, Haodong Gong, Junjie Peng, Xingqin Wang, Songtao Qi, Junxiang Peng
JOURNAL/nrgr/04.03/01300535-202410000-00026/figure1/v/2024-02-06T055622Z/r/image-tiff Previous studies have shown that growth hormone can regulate hypothalamic energy metabolism, stress, and hormone release. Therefore, growth hormone has great potential for treating hypothalamic injury. In this study, we established a specific hypothalamic axon injury model by inducing hypothalamic pituitary stalk electric lesions in male mice. We then treated mice by intraperitoneal administration of growth hormone. Our results showed that growth hormone increased the expression of insulin-like growth factor 1 and its receptors, and promoted the survival of hypothalamic neurons, axonal regeneration, and vascular reconstruction from the median eminence through the posterior pituitary...
October 1, 2024: Neural Regeneration Research
https://read.qxmd.com/read/38483236/the-relationship-between-manifestation-of-diabetes-insipidus-and-estimated-glomerular-filtration-rate-in-brain-death-implications-require-clarification
#8
JOURNAL ARTICLE
Ari R Joffe, Michael Nair-Collins
No abstract text is available yet for this article.
April 1, 2024: Critical Care Medicine
https://read.qxmd.com/read/38481609/cumulative-summation-analysis-of-learning-curve-for-endoscopic-endonasal-transsphenoidal-resection-of-craniopharyngiomas
#9
JOURNAL ARTICLE
Jiye Ye, Ruiting Yang, Jie Wu, Chunming Xu, Tao Hong
BACKGROUND: To evaluate the cumulative summation (CUSUM) analysis of the learning curve for Endoscopic Endonasal Transsphenoidal resection of craniopharyngioma (EETC). METHODS: Retrospectively analyzed the clinical data of 113 patients who underwent EETC by the same neurosurgery team of the first affiliated Hospital of Nanchang University from June 2012 to November 2020. The learning curve was created by the CUSUM method and analyzed, which was divided into two groups: the learning stage and stable stage based on the learning curve trend...
2024: Frontiers in Surgery
https://read.qxmd.com/read/38476426/factors-predicting-outcomes-of-endoscopic-endonasal-approach-in-craniopharyngioma-patients
#10
JOURNAL ARTICLE
Chin Taweesomboonyat, Raywat Noiphithak, Pree Nimmannitya, Sakchai Sae-Heng
OBJECTIVES: Endoscopic endonasal approach (EEA) is commonly used for resection of craniopharyngioma (CP). Treatment outcomes of EEA for CP were related to numerous factors; however, they have been evaluated in few studies. The objective of this study is to investigate factors associated with the outcomes of CP following this operation. MATERIALS AND METHODS: The records of patients with CP, who underwent EEA at our institution from January 2014 to June 2022, were retrospectively reviewed...
2024: Journal of Neurosciences in Rural Practice
https://read.qxmd.com/read/38468659/comparing-redo-surgery-and-stereotactic-radiosurgery-for-recurrent-residual-and-or-tumors-showing-progression-in-nonfunctioning-pituitary-adenomas-a-systematic-review-and-meta-analysis
#11
REVIEW
Muhammad Yousuf Ul Islam, Saad Akhtar, Roua Nasir, Saad Bin Anis, Haissan Iftikhar, Farhan Raza Khan, Russell Seth Martins, Muhammad Ehsan Bari, Urooba Ahmed
BACKGROUND: Non-functioning pituitary adenomas (NFPAs) are well-differentiated benign tumors originating from the adenohypophyseal cells of the pituitary gland. They present with headaches, visual disorders, or cranial nerve deficits. NFPAs can recur, progress, or present as residual tumors. We, therefore, conducted this review to compare the effects of both revision surgery and stereotactic surgery on tumor size, visual status, endocrine status, and complications. METHODS: A systematic review of published literature on recurrent, residual, or progressing NFPAs that underwent redo surgery or stereotactic radiosurgery from the inception till June 2020 was conducted as per Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines...
2024: Surgical Neurology International
https://read.qxmd.com/read/38468645/secondary-hypophysitis-associated-with-rathke-s-cleft-cyst-resembling-a-pituitary-abscess
#12
Eri Inoue, Irfan Kesumayadi, Shingo Fujio, Ryutaro Makino, Tomoko Hanada, Keisuke Masuda, Nayuta Higa, Shigeru Kawade, Yuichiro Niihara, Hirosuke Takagi, Ikumi Kitazono, Yutaka Takahashi, Ryosuke Hanaya
BACKGROUND: Although rare, cases of hypophysitis resembling a pituitary abscess (PA) have been reported. Differential diagnosis between hypophysitis and PA is crucial as the two diseases require different treatments. CASE DESCRIPTION: A 38-year-old woman with headaches underwent head magnetic resonance imaging (MRI), which revealed an 11-mm mass lesion in the sella turcica. Due to breastfeeding, contrast-enhanced MRI was avoided. Pituitary adenomas and Rathke's cleft cyst (RCC) were suspected, and she was initially treated conservatively...
2024: Surgical Neurology International
https://read.qxmd.com/read/38467866/everything-old-is-new-again-revisiting-hypophysectomy-for-the-treatment-of-refractory-cancer-related-pain-a-systematic-review
#13
REVIEW
Timoteo Almeida, Bernardo A Monaco, Fernando Vasconcelos, Guilherme S Piedade, Alexis Morell, Ifeanyichukwu Ogobuiro, Guilherme A Lepski, Luciano L Furlanetti, Karina K Cordeiro, Carolina Benjamin, Jonathan R Jagid, Joacir G Cordeiro
Cancer-related pain is a common and debilitating condition that can significantly affect the quality of life of patients. Opioids, NSAIDs, and antidepressants are among the first-line therapies, but their efficacy is limited or their use can be restricted due to serious side effects. Neuromodulation and lesioning techniques have also proven to be a valuable instrument for managing refractory pain. For patients who have exhausted all standard treatment options, hypophysectomy may be an effective alternative treatment...
March 12, 2024: Neurosurgical Review
https://read.qxmd.com/read/38465704/long-term-clinical-follow-up-of-four-patients-with-wolfram-syndrome-and-urodynamic-abnormalities
#14
JOURNAL ARTICLE
Nimisha S Dange, Nikhil Shah, Chirantap Oza, Jyoti Sharma, Jyoti Singhal, Sushil Yewale, Shruti Mondkar, Shriniwas Ambike, Vaman Khadilkar, Anuradha V Khadilkar
OBJECTIVES: Wolfram syndrome is characterised by insulin-dependent diabetes (IDDM), diabetes insipidus (DI), optic atrophy, sensorineural deafness and neurocognitive disorders. The DIDMOAD acronym has been recently modified to DIDMOAUD suggesting the rising awareness of the prevalence of urinary tract dysfunction (UD). End stage renal disease is the commonest cause of mortality in Wolfram syndrome. We present a case series with main objective of long term follow up in four children having Wolfram syndrome with evaluation of their urodynamic profile...
March 12, 2024: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://read.qxmd.com/read/38465024/endocrinopathies-in-a-pediatric-patient-post-anatomical-hemispherectomy-for-rasmussen-s-encephalitis-treatment-a-case-report
#15
Jaron C Sanchez, Markeeta T Belmar, Jason C Sanchez, Kenny Nguygen
Hemispherectomy is a neurosurgical procedure that is frequently performed in pediatric patients diagnosed with Rasmussen's encephalitis. Postoperative complications include immediate complications such as hydrocephalus and hemorrhage and behavioral complications such as language impairments and contralateral weakness. However, there are limited studies or case reports that address the potential endocrinopathies associated with this and other pediatric epileptic surgeries. This case report describes the endocrinopathies following an anatomical hemispherectomy procedure...
February 2024: Curēus
https://read.qxmd.com/read/38462927/evaluation-of-copeptin-in-children-after-stimulation-with-clonidine-or-l-dopa
#16
JOURNAL ARTICLE
Aristeidis Giannakopoulos, Dimitra Kritikou, Dionisios Chrysis
OBJECTIVES: Arginine-stimulated serum copeptin has been proposed as a new method to diagnose arginine vasopressin (AVP) deficiency in children and adolescents. Herein we investigated the secretagogic potential of clonidine or L-Dopa on the copeptin serum levels in children. METHODS: Eight stimulation tests (4 with clonidine and 4 with L-Dopa) were performed in eight children (5 boys and 3 girls) with a median age of 6.5 years-old, evaluated for short stature due to possible growth hormone deficiency...
March 12, 2024: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://read.qxmd.com/read/38462093/the-influence-of-insulin-induced-hypoglycemia-on-copeptin-concentrations
#17
JOURNAL ARTICLE
Penelope Trimpou, Ioannis Bounias, Olof Ehn, Ola Hammarsten, Oskar Ragnarsson
Plasma copeptin is a biomarker that reflects arginine vasopressin (AVP) secretion. In this study we measured copeptin during insulin tolerance test (ITT) in 65 patients referred to our department for evaluation of anterior pituitary function. Plasma for measurements of copeptin were collected at the start of the test and regurarly up to 120minutes thereafter. Of 60 patients who developed significant hypoglycemia and were included in the analyses, 13 (22%) had corticotropic deficiency, 11 (18%) had thyreotropic deficiency, 33 (55%) had growth hormone deficiency and 4 (6%) had AVP deficieny (AVPD)...
March 8, 2024: Peptides
https://read.qxmd.com/read/38452869/position-statement-on-the-diagnosis-and-management-of-congenital-pituitary-deficiency-in-adults-the-french-national-diagnosis-and-treatment-protocol-ndtp
#18
JOURNAL ARTICLE
S Castets, F Albarel, A Bachelot, G Brun, J Bouligand, C Briet, E Bui Quoc, C Cazabat, C Chabbert-Buffet, S Christin-Maitre, C Courtillot, T Cuny, G De Filippo, B Donadille, F Illouz, I Pellegrini, Y Reznik, A Saveanu, N Teissier, P Touraine, M C Vantyghem, J Vergier, J Léger, T Brue, R Reynaud
Pituitary deficiency, or hypopituitarism, is a rare chronic disease. It is defined by insufficient synthesis of one or more pituitary hormones (growth hormone, TSH, ACTH, LH-FSH, prolactin), whether or not associated with arginine vasopressin deficiency (formerly known as diabetes insipidus). In adult patients, it is usually acquired (notably during childhood), but can also be congenital, due to abnormal pituitary development. The present study focuses on congenital pituitary deficiency in adults, from diagnosis to follow-up, including special situations such as pregnancy or the elderly...
March 5, 2024: Annales D'endocrinologie
https://read.qxmd.com/read/38451095/-one-and-a-half-interdural-transcavernous-pituitary-transposition-rotation-for-protection-of-hypophyseal-portal-system-in-adult-peripheral-retroinfundibular-craniopharyngioma
#19
JOURNAL ARTICLE
Ao Shen, Yang Yu, Liang Lyu, Shu Jiang, Dongjie Zhou, Jianguo Xu, Peizhi Zhou
BACKGROUND AND OBJECTIVES: Craniopharyngiomas originate from the pituitary stalk (PS) and extend along the pituitary-hypothalamic axis. Peripheral retroinfundibular craniopharyngiomas, particularly, may have worse surgery outcomes than other types. This study aims to investigate the advantage of using "one-and-a-half" interdural transcavernous pituitary transposition/rotation to dissect the tumor from the residual stalk and hypophyseal portal system for this subtype of craniopharyngioma...
March 7, 2024: Operative Neurosurgery (Hagerstown, Md.)
https://read.qxmd.com/read/38450903/congenital-nephrogenic-diabetes-insipidus-treated-with-acetazolamide
#20
Wesley Du Plessis, Mogamat-Yazied Chothia
Congenital nephrogenic diabetes insipidus (CNDI) is a rare disorder. The condition is characterised by an inability of distal nephron segments to respond to normal or raised concentrations of serum antidiuretic hormone. In this report, we describe the case of a 13-year-old male known with CNDI who experienced a pedestrian vehicle accident leading to coma following a head injury. Intra-operatively, severe hypernatraemia and polyuria were observed. Following an inadequate response to conventional therapy, acetazolamide was prescribed resulting in an immediate response to therapy...
March 7, 2024: Nephrology
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