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Schwartz formula

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https://www.readbyqxmd.com/read/28182833/comparative-effectiveness-of-mycophenolate-mofetil-for-the-treatment-of-childhood-onset-proliferative-lupus-nephritis
#1
Simon Y Tian, Earl D Silverman, Eleanor Pullenayegum, Patrick E Brown, Joseph Beyene, Brian M Feldman
OBJECTIVES: Although childhood-onset proliferative lupus nephritis (cPLN) leads to significant morbidity and mortality, there is no trial evidence to support the treatment effectiveness of any therapy for cPLN. Marginal structural models (MSMs) enable us to estimate treatment effectiveness using observational data while accounting for confounding by indication. METHODS: We used prospectively collected data to examine the effect of mycophenolate mofetil (MMF), compared to the use of other therapies, on the long-term outcome of our cPLN cohort (age at onset of PLN < 18 years)...
February 9, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28133546/glomerular-and-tubular-renal-function-after-repeated-once-daily-tobramycin-courses-in-cystic-fibrosis-patients
#2
Florian Stehling, Rainer Büscher, Jörg Grosse-Onnebrink, Peter F Hoyer, Uwe Mellies
Introduction. Antibiotic treatment regimens against Pseudomonas aeruginosa lung infection in cystic fibrosis (CF) patients often include aminoglycoside antibiotics that may cause chronic renal failure after repeated courses. Aminoaciduria is an early marker of acute aminoglycoside-induced renal tubular dysfunction. We hypothesized that urinary amino acid reabsorption is decreased after repeated once-daily tobramycin therapies. Methods. In this prospective cross-sectional study creatinine clearance was estimated by the Schwartz and the Cockcroft-Gault formula...
2017: Pulmonary Medicine
https://www.readbyqxmd.com/read/27995019/colombeau-products-of-distributions
#3
Marija Miteva, Biljana Jolevska-Tuneska, Tatjana Atanasova-Pacemska
In this paper, some products of distributions are derived. The results are obtained in Colombeau algebra of generalized functions, which is the most relevant algebraic construction for dealing with Schwartz distributions. Colombeau algebra [Formula: see text] contains the space [Formula: see text] of Schwartz distributions as a subspace, and has a notion of 'association' that allows us to evaluate the results in terms of distributions.
2016: SpringerPlus
https://www.readbyqxmd.com/read/27982632/direct-approach-to-quantum-tunneling
#4
Anders Andreassen, David Farhi, William Frost, Matthew D Schwartz
The decay rates of quasistable states in quantum field theories are usually calculated using instanton methods. Standard derivations of these methods rely in a crucial way upon deformations and analytic continuations of the physical potential and on the saddle-point approximation. While the resulting procedure can be checked against other semiclassical approaches in some one-dimensional cases, it is challenging to trace the role of the relevant physical scales, and any intuitive handle on the precision of the approximations involved is at best obscure...
December 2, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27981896/screening-of-renal-dysfunction-among-burkitt-lymphoma-survivors-by-novel-markers
#5
Laila Metwaly Sherief, Doaa Mohammed Youssef, Hanan Saker Sherbiny, Elhamy Abdelkhalek, Mohamed Talaat, Naglaa Ali Khalifa
BACKGROUND: Burkitt lymphoma (BL) represents the most common pathological type of non-Hodgkin lymphoma in our region. Recently, high success rates have been achieved in BL treatment. Little is known about long-term renal dysfunction in this vulnerable group. In the present study, we tried to detect early chronic kidney diseases (CKD) among BL survivors by using novel screening modalities. PATIENTS AND METHODS: we investigated 53 children (aged 10 ± 2.8 years, 34 boys) who successfully treated for Burkitt lymphoma, based on LMB96 protocol, as "patient group" and 30 children as control...
December 16, 2016: Hematology (Amsterdam, Netherlands)
https://www.readbyqxmd.com/read/27902155/the-abcs-of-how-we-learn-26-scientifically-proven-approaches-how-they-work-and-when-to-use-them-schwartz-daniel-l-tsang-jessica-m-and-blair-kristen-p-the-abcs-of-how-we-learn-26-scientifically-proven-approaches-how-they-work-and-when-to-use-them-384pp-%C3%A2-17
#6
https://www.readbyqxmd.com/read/27900958/renal-shear-wave-velocity-and-estimated-glomerular-filtration-rate-in-children-with-chronic-kidney-disease
#7
Costanza Bruno, Milena Brugnara, Rocco Micciolo, Mariangela Cecchetto, Michele Zuffante, Alessandra Bucci, Marco Zaffanello
A shear wave velocity (SWV) value obtained by the acoustic radiation force impulse technique depends on tissue elasticity. We investigated the relationship between SWV values and the estimated glomerular filtration rate (eGFR) in children with chronic kidney disease. A total of 29 patients were enrolled in the study. There were 18 primary and 11 secondary cases of vesicoureteral reflux. eGFR was calculated using Schwartz's formulas (2012). Partial eGFR for each kidney was assessed by multiplying the eGFR by the percentage of renal function measured by means of renal (99m)Tc-dimercaptosuccinic acid scintigraphy...
November 2016: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/27856008/comprehensive-renal-function-evaluation-in-patients-treated-for-synchronous-bilateral-wilms-tumor
#8
Rodrigo B Interiano, M Beth McCarville, Noel Delos Santos, Shenghua Mao, Jianrong Wu, Jeffrey S Dome, Kathleen Kieran, Mark A Williams, Rachel C Brennan, Matthew J Krasin, Daniel M Green, Andrew M Davidoff
OBJECTIVES: The purpose of this study was to perform a comprehensive assessment of long-term renal function in patients treated at our institution for synchronous bilateral Wilms tumor (BWT) and to determine the optimal method for estimating glomerular filtration rate (eGFR). METHODS: Surgical approach, adjuvant therapy, and pathology reports were reviewed for patients with at least six months follow-up from definitive surgery. eGFRs, as assessed by the Schwartz and Chronic Kidney Disease in Children (CKiD) formulas, were compared to measured GFR (mGFR) determined by (99m)Tc-DTPA scanning...
January 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27782758/a-cluster-randomized-trial-of-tailored-breastfeeding-support-for-women-with-gestational-diabetes
#9
Alison M Stuebe, Karen Bonuck, Reuben Adatorwovor, Todd A Schwartz, Diane C Berry
BACKGROUND: Women with gestational diabetes mellitus (GDM) and their infants are at increased risk of developing metabolic disease; however, longer breastfeeding is associated with a reduction in these risks. We tested an intervention to increase breastfeeding duration among women with GDM. MATERIALS AND METHODS: We conducted a cluster randomized trial to determine the efficacy of a breastfeeding education and support program for women with GDM. Women were enrolled between 22 and 36 weeks of pregnancy and cluster randomized to an experimental lifestyle intervention or wait-list control group...
December 2016: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/27779134/a-numerical-study-on-the-oblique-focus-in-mr-guided-transcranial-focused-ultrasound
#10
Alec Hughes, Yuexi Huang, Aki Pulkkinen, Michael L Schwartz, Andres M Lozano, Kullervo Hynynen
Recent clinical data showing thermal lesions from treatments of essential tremor using MR-guided transcranial focused ultrasound shows that in many cases the focus is oblique to the main axis of the phased array. The potential for this obliquity to extend the focus into lateral regions of the brain has led to speculation as to the cause of the oblique focus, and whether it is possible to realign the focus. Numerical simulations were performed on clinical export data to analyze the causes of the oblique focus and determine methods for its correction...
November 21, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27765666/safety-efficacy-and-pharmacokinetics-of-a-single-tablet-regimen-containing-elvitegravir-cobicistat-emtricitabine-and-tenofovir-alafenamide-in-treatment-naive-hiv-infected-adolescents-a-single-arm-open-label-trial
#11
Aditya H Gaur, Hilda Kizito, Wasana Prasitsueubsai, Natella Rakhmanina, Mohammed Rassool, Rana Chakraborty, Jagmohan Batra, Pope Kosalaraksa, Wicharn Luesomboon, Danielle Porter, Yongwu Shao, Michael Myers, Lillian Ting, Devi SenGupta, Erin Quirk, Martin S Rhee
BACKGROUND: The prodrug tenofovir alafenamide is associated with improved renal and bone safety compared with tenofovir disoproxil fumarate. We aimed to assess safety, pharmacokinetics, and efficacy of this single-tablet, fixed-dose combination of elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide in HIV-infected, treatment-naive adolescents. METHODS: We did a 48 week, single-arm, open-label trial in treatment-naive adolescents with HIV from ten hospital clinics in South Africa, Thailand, Uganda, and the USA...
December 2016: Lancet HIV
https://www.readbyqxmd.com/read/27705955/changing-head-model-extent-affects-finite-element-predictions-of-transcranial-direct-current-stimulation-distributions
#12
Aprinda Indahlastari, Munish Chauhan, Benjamin Schwartz, Rosalind J Sadleir
OBJECTIVE: In this study, we determined efficient head model sizes relative to predicted current densities in transcranial direct current stimulation (tDCS). APPROACH: Efficiency measures were defined based on a finite element (FE) simulations performed using nine human head models derived from a single MRI data set, having extents varying from 60%-100% of the original axial range. Eleven tissue types, including anisotropic white matter, and three electrode montages (T7-T8, F3-right supraorbital, Cz-Oz) were used in the models...
December 2016: Journal of Neural Engineering
https://www.readbyqxmd.com/read/27689114/correlation-between-cystatin-c-based-formulas-schwartz-formula-and-urinary-creatinine-clearance-for-glomerular-filtration-rate-estimation-in-children-with-kidney-disease
#13
Afshin Safaei-Asl, Mercede Enshaei, Abtin Heydarzadeh, Shohreh Maleknejad
INTRODUCTION: Assessment of glomerular filtration rate (GFR) is an important tool for monitoring renal function. OBJECTIVES: Regarding to limitations in available methods, we intended to calculate GFR by cystatin C (Cys C) based formulas and determine correlation rate of them with current methods. PATIENTS AND METHODS: We studied 72 children (38 boys and 34 girls) with renal disorders. The 24 hour urinary creatinine (Cr) clearance was the gold standard method...
2016: Journal of Renal Injury Prevention
https://www.readbyqxmd.com/read/27648290/plasma-glucose-and-insulin-response-to-two-oral-nutrition-supplements-in-adults-with-type-2-diabetes-mellitus
#14
Maureen B Huhmann, Kristen N Smith, Sherwyn L Schwartz, Stacie K Haller, Sarah Irvin, Sarah S Cohen
OBJECTIVE: The purpose of this clinical trial was to compare the glucose usage of two oral nutritional supplement (ONS) products and to assess whether a diabetes-specific formulation provides improved glucose stabilization and management compared with a standard formula. RESEARCH DESIGN AND METHODS: A total of 12 subjects with type 2 diabetes (7 males and 5 females) completed a randomized, cross-over design trial. Each subject consumed isocaloric amounts of either the standard ONS or the diabetes-specific formula ONS on different dates, 1 week apart...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27613652/analytic-modeling-of-neural-tissue-i-a-spherical-bidomain
#15
Benjamin L Schwartz, Munish Chauhan, Rosalind J Sadleir
Presented here is a model of neural tissue in a conductive medium stimulated by externally injected currents. The tissue is described as a conductively isotropic bidomain, i.e. comprised of intra and extracellular regions that occupy the same space, as well as the membrane that divides them, and the injection currents are described as a pair of source and sink points. The problem is solved in three spatial dimensions and defined in spherical coordinates [Formula: see text]. The system of coupled partial differential equations is solved by recasting the problem to be in terms of the membrane and a monodomain, interpreted as a weighted average of the intra and extracellular domains...
December 2016: Journal of Mathematical Neuroscience
https://www.readbyqxmd.com/read/27542858/cystatin-c-calculated-glomerular-filtration-rate-a-marker-of-early-renal-dysfunction-in-patients-with-neuropathic-bladder
#16
Pankaj P Dangle, Omar Ayyash, Audry Kang, Carlton Bates, Janelle Fox, Heidi Stephany, Glenn Cannon
OBJECTIVE: To asses if cystatin c-calculated glomerular filtration rate (GFR) can reveal chronic kidney disease (CKD) not detected by creatinine-based calculations in a larger prospective cohort of children with myelomeningocele (MMC). Wheelchair-bound MMC patients frequently have low muscle mass, and assessing renal deterioration based on creatinine-based GFR is imprecise. MMC patients are also at risk for end-stage renal disease. METHODS: Prospectively enrolled patients with MMC underwent annual serum creatinine and cystatin c testing...
August 16, 2016: Urology
https://www.readbyqxmd.com/read/27508764/-op-6a-01-renalase-in-children-with-glomerular-kidney-diseases
#17
P Skrzypczyk, M Panczyk-Tomaszewska, J Przychodzien, M Mizerska-Wasiak, E Kuzma-Mroczkowska, E Gorska, A Stelmaszczyk-Emmel
OBJECTIVE: Renalase is a protein produced mainly by kidneys. Renalase inactivates circulating catecholamines catalyzing process of their oxidation. Studies in adults with kidney disease suggest that renalase may play a role in pathogenesis of hypertension and target organ damage. The aim of the study was to assess level of renalase in children with glomerular kidney diseases and to find the relation between renalase level and clinical parameters in this group of patients. DESIGN AND METHOD: In 78 children (47 M, 31F) aged from 3...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27499411/salvageability-of-renal-function-following-renal-revascularisation-in-children-with-takayasu-s-arteritis-induced-renal-artery-stenosis
#18
Patience Ngozi Obiagwu, Priya Gajjar, Mignon McCulloch, Christian Scott, Alp Numanoglu, Peter Nourse
BACKGROUND: Renal artery revascularisation procedures are usually carried out on children with renal artery stenosis from varied causes, including Takayasu's arteritis. Reports on the outcome of such procedures in children usually refer to the improvement in blood pressure, with only minimal mention of effects on renal function. OBJECTIVE: Salvageability of renal function in children who underwent renal revascularisation for Takayasu's arteritis-induced renal artery stenosis (TARAS) was the focus of this study...
August 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/27353352/masked-hypertension-and-allograft-function-in-pediatric-and-young-adults-kidney-transplant-recipients
#19
Gilad Hamdani, Edward J Nehus, David K Hooper, Mark M Mitsnefes
Masked hypertension is a common complication of pediatric kidney transplantation. While office hypertension is known to be associated with worse short- and long-term graft function, the role of masked hypertension in allograft dysfunction is not clear. We conducted a retrospective cross-sectional analysis of 77 consecutive pediatric kidney transplant recipients who had routine 24-h ambulatory blood pressure monitoring with the aims to estimate the prevalence of masked hypertension and examine its association with allograft function...
December 2016: Pediatric Transplantation
https://www.readbyqxmd.com/read/27312122/zeaxanthin-based-dietary-supplement-and-topical-serum-improve-hydration-and-reduce-wrinkle-count-in-female-subjects
#20
Steve Schwartz, Emily Frank, Dennis Gierhart, Paula Simpson, Robert Frumento
BACKGROUND: Dietary modification, through supplementation and elimination diets, has become an area of interest to help slow skin aging, reduce symptom severity or prevent reoccurrence of certain dermatologic conditions [Clinical Dermatology vol. 31 (2013) 677-700]. Free radical components (reactive oxygen species or ROS) or lipid peroxide (LPO) is involved in the pathogenesis and progression of accelerated skin aging when prolonged oxidative stress occurs. The use of antioxidant-related therapies such as nutraceuticals is of particular interest in restoring skin homeostasis...
June 17, 2016: Journal of Cosmetic Dermatology
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