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https://www.readbyqxmd.com/read/28717766/practice-and-impact-of-multidisciplinary-tumor-boards-on-patient-management-a-prospective-study
#1
Raghid N Charara, Firas Y Kreidieh, Rania A Farhat, Karine A Al-Feghali, Katia E Khoury, Ali Haydar, Lara Nassar, Ghina Berjawi, Ali Shamseddine, Nagi S El Saghir
PURPOSE: Multidisciplinary tumor boards (MTBs) have become commonplace. The use, attendance, and function of MTBs need continued assessment and improvement. METHODS: We prospectively recorded and assessed all cases presented at MTBs between October 2013 and December 2014. Data were collected before and during each MTB. Data were analyzed using SPSS for Windows version 23 (SPSS, Chicago, IL). RESULTS: Five hundred three cases were presented: 234 cases (46%) at GI cancer MTBs, 149 cases (29...
June 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/28625619/intra-thoracic-chemo-hyperthermia-for-pleural-recurrence-of-thymoma
#2
Jean Michel Maury, Nicolas Girard, Mayeul Tabutin, Renaud Grima, Lara Chalabreysse, Isabelle Pavlakovic, Annie Sayag-Beaujard, Caroline Leroux, Pierre-Jean Souquet, Olivier Glehen, François Tronc
BACKGROUND: Pleural recurrences are a hallmark of thymomas, and represent a challenge for multidisciplinary management. The purpose of this study was to assess the feasibility and the results in terms of morbidity, mortality and survival rates, of Intra-Thoracic Chemo-Hyperthermia (ITCH) for the treatment of pleural recurrences of thymomas. METHODS: Retrospective analysis of 19 consecutives patients between 1997 and 2015 treated by surgical cytoreduction (pleurectomy) followed by ITCH with 25mg/m(2) of mitomycin, and 50mg/m(2) of Cisplatin...
June 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/28446984/salvage-surgery-after-high-dose-radiotherapy
#3
REVIEW
Annemie Van Breussegem, Jeroen M Hendriks, Patrick Lauwers, Paul E Van Schil
Salvage surgery is a relatively new entity in thoracic surgery and oncology. Salvage resection after radiotherapy refers to surgery as only remaining therapeutic option in patients who were treated with high-dose stereotactic radiotherapy (SRT) for early-stage lung cancer or full-dose chemoradiation for locally advanced lung cancer. Indications include locally progressive tumors, recurrent local or locoregional disease, or specific complications after radiotherapy such as lung abscesses or infected, necrotic cavities...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28395501/multidisciplinary-team-approach-for-the-management-of-patients-with-locally-advanced-non-small-cell-lung-cancer-searching-the-evidence-to-guide-the-decision
#4
REVIEW
In-Jae Oh, Sung-Ja Ahn
Locally advanced non-small cell lung cancer (LA-NSCLC) is composed of heterogeneous subgroups that require a multidisciplinary team approach in order to ensure optimal therapy for each patient. Since 2010, the National Comprehensive Cancer Network has recommended chemoradiation therapy (CRT) for bulky mediastinal disease and surgical combination for those patients with single-station N2 involvement who respond to neoadjuvant therapy. According to lung cancer tumor boards, thoracic surgeons make a decision on the resectability of the tumor, if it is determined to be unresectable, concurrent CRT (CCRT) is considered the next choice...
March 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/28338470/reducing-scan-angle-using-adaptive-prior-knowledge-for-a-limited-angle-intrafraction-verification-live-system-for-conformal-arc-radiotherapy
#5
Yawei Zhang, Fang-Fang Yin, You Zhang, Lei Ren
The purpose of this study is to develop an adaptive prior knowledge guided image estimation technique to reduce the scan angle needed in the limited-angle intrafraction verification (LIVE) system for 4D-CBCT reconstruction. The LIVE system has been previously developed to reconstruct 4D volumetric images on-the-fly during arc treatment for intrafraction target verification and dose calculation. In this study, we developed an adaptive constrained free-form deformation reconstruction technique in LIVE to further reduce the scanning angle needed to reconstruct the 4D-CBCT images for faster intrafraction verification...
May 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28047067/su-f-t-520-dosimetric-comparison-of-radiation-treatment-plans-for-whole-breast-irradiation-between-3d-conformal-in-prone-and-supine-positions-vs-vmat-and-imrt-in-supine-positions
#6
A Bejarano Buele, E Parsai
PURPOSE: The target volume for Whole Breast Irradiation (WBI) is dictated by location of tumor mass, breast tissue distribution, and involvement of lymph nodes. Dose coverage and Organs at Risk (OARs) sparing can be difficult to achieve in patients with unfavorable thoracic geometries. For these cases, inverse-planned and 3D-conformal prone treatments can be alternatives to traditional supine 3D-conformal plans. A dosimetric comparison can determine which of these techniques achieve optimal target coverage while sparing OARs...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/27906470/retrospective-evaluation-of-whole-body-computed-tomography-for-tumor-staging-in-dogs-with-primary-appendicular-osteosarcoma
#7
Jessica L Talbott, Sarah E Boston, Rowan J Milner, Amandine Lejeune, Carlos H de M Souza, Kelvin Kow, Nicholas J Bacon, Jorge A Hernandez
OBJECTIVE: To evaluate whole body computed tomography (CT) for staging canine appendicular osteosarcoma. STUDY DESIGN: Retrospective case series. ANIMALS: Client-owned dogs diagnosed with appendicular osteosarcoma (n=39). METHODS: Medical records for client-owned dogs diagnosed with appendicular osteosarcoma from August 2008 to July 2014 were reviewed. Dogs were included if they had a confirmed diagnosis of appendicular osteosarcoma and were staged using whole body CT...
January 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/27777885/male-papillary-breast-cancer-treated-by-wide-resection-and-latissimus-dorsi-flap-reconstruction-a-case-report-and-review-of-the-literature
#8
Malgorzata Banys-Paluchowski, Eike Burandt, Joanna Banys, Stefan Geist, Guido Sauter, Natalia Krawczyk, Peter Paluchowski
Breast cancer (BC) in men represents between 0.5% and 1% of all BC diagnosed each year. We report a case of advanced BC in a 62-year-old male treated at our interdisciplinary Breast Cancer Center. The patient presented with a newly diagnosed large, symptomatic mass in his left breast. Clinical examination showed a not movable mass of 16 cm diameter, deforming the whole breast; the overlying skin was livid and hypervascularized. Enlarged lymph nodes were palpable in the axillary pit. He had no concomitant diseases at time of presentation...
October 10, 2016: World Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27534786/-multiple-primary-lung-cancer-a%C3%A2-case-report-and-literature-review
#9
REVIEW
Z Chovanec, I Čapov, A Peštál, M Benej, M Páral
BACKGROUND: Multiple primary lung cancer is a relatively rare nosological entity. This case report is a reminder and points out the pitfalls of its diagnosis and therapy. CASE REPORT: A 62-year-old patient was indicated for surgical therapy for non-small cell lung cancer of the middle lobe and right lung, which were diagnosed during a screening investigation after the patient had undergone previous mastectomy of the right breast with axillary dissection for invasive ductal adenocarcinoma...
2016: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
https://www.readbyqxmd.com/read/27376075/18f-fdg-positron-emission-tomography-an-innovative-technique-for-the-diagnosis-of-a-canine-lameness
#10
Kelly Mann, Juliette Hart, Felix Duerr
INTRODUCTION: Positron emission tomography (PET) imaging with fluorine-18-fluorodeoxyglucose (18F-FDG) is widely known for its use in the diagnosis and tracking of primary and metastatic tumors via uptake and retention of the radiopharmaceutical by hypermetabolic cells. 18F-FDG is also used to study the normal physiology of glucose uptake, metabolism, and muscle activity during and after exercise. BACKGROUND: A pilot study adding PET imaging to the diagnostic evaluation of canine patients undergoing computed tomography (CT) for mild or intermittent thoracic and pelvic limb lameness is ongoing...
2016: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/26679656/-errors-in-six-degree-of-freedom-pose-estimation-of-spine-tumors-assessed-by-image-guided-radiotherapy
#11
Ping Jiang, Shun Zhou, Jun-jie Wang, Rui-jie Yang, Zi-yi Liu, Shu-kun Jiang, Wei Wang
OBJECTIVE: To evaluate the six-degree setup errors of tumors of cervical vertebra, thoracic vertebra and lumbar vertebra by image guided radiotherapy. METHODS: From May 2013 to June 2014, 30 patients with spinal malignant tumors(10 patients of cervical vertebra, thoracic vertebra and lumbar vertebra respectively) were treated with Elekata Synergy accelerator (Elekta company,Sweden). Six-degree set up errors were corrected using HexaPODTMevoRT bed under image of on board cone beam computed tomography (CBCT) guided...
December 18, 2015: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/26588021/chemical-exchange-saturation-transfer-mr-imaging-preliminary-results-for-differentiation-of-malignant-and-benign-thoracic-lesions
#12
Yoshiharu Ohno, Masao Yui, Hisanobu Koyama, Takeshi Yoshikawa, Shinichiro Seki, Yoshiko Ueno, Mitsue Miyazaki, Cheng Ouyang, Kazuro Sugimura
PURPOSE: To prospectively evaluate the capability of amide proton transfer-weighted chemical exchange saturation transfer magnetic resonance (MR) imaging for characterization of thoracic lesions. MATERIALS AND METHODS: The institutional review board approved this study, and written informed consent was obtained from 21 patients (13 men and eight women; mean age, 72 years) prior to enrollment. Each patient underwent chemical exchange saturation transfer MR imaging by using respiratory-synchronized half-Fourier fast spin-echo imaging after a series of magnetization transfer pulses...
May 2016: Radiology
https://www.readbyqxmd.com/read/26480862/-surgical-treatment-of-lung-metastases-of-colorectal-carcinoma%C3%A2-%C3%A2-survival-and-prognostic-factors
#13
A Dzian, M Uhnák, J Hamžík
BACKROUND: Colorectal carcinoma has the third highest incidence of all tumor diseases in the world. In the long term, Slovak republic is among countries with highest occurrence of this disease. About 25% of patients have distant metastases at the time of diagnosis, and about 50% of patients progress. The first possibility of colorectal carcinoma lung metastases treatment is metastasectomy which may have a curative character. MATERIALS AND METHODS: In this paper, the authors retrospectively evaluated 50 patients who had undergone surgical treatment to establish the diagnosis of colorectal carcinoma lung metastases at the Clinic of thoracic surgery of JLF UK and UH Martin between 2003 and 2014...
2015: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
https://www.readbyqxmd.com/read/26471696/tnm-staging-of-non-small-cell-lung-cancer-comparison-of-pet-mr-and-pet-ct
#14
Martin W Huellner, Felipe de Galiza Barbosa, Lars Husmann, Carsten M Pietsch, Cäcilia E Mader, Irene A Burger, Paul Stolzmann, Gaspar Delso, Thomas Frauenfelder, Gustav K von Schulthess, Patrick Veit-Haibach
UNLABELLED: The purpose of this study was to compare the diagnostic accuracy of whole-body unenhanced PET/MR with that of PET/CT in determining the stage of non-small cell lung cancer. METHODS: This study was approved by the institutional review board and by national government authorities. Forty-two consecutive patients referred for the initial staging of non-small cell lung cancer underwent whole-body imaging with a sequential trimodality PET/CT/MR system. PET/MR and PET/CT datasets were evaluated separately, and a TNM stage was assigned on the basis of the image analysis...
January 2016: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/26270521/impact-of-nurse-navigation-on-timeliness-of-diagnostic-medical-services-in-patients-with-newly-diagnosed-lung-cancer
#15
Charles A Kunos, Sally Olszewski, Eric Espinal
BACKGROUND: The Summa Cancer Institute in Akron, Ohio, sought to improve access to and the timeliness of lung cancer care by hiring an oncology-certified nurse navigator. The nurse navigator was charged with coordinating diagnostic procedures and specialty oncology consultations, and with facilitating a multidisciplinary thoracic oncology tumor board. OBJECTIVE: To test the hypothesis that nurse navigation would improve the timeliness of and access to diagnostic medical services among men and women with newly diagnosed lung cancer...
June 2015: Journal of Community and Supportive Oncology
https://www.readbyqxmd.com/read/26137086/nipple-sparing-mastectomy-in-breast-cancer-patients-the-role-of-adjuvant-radiotherapy-review
#16
Stefan Janssen, Edna Holz-Sapra, Dirk Rades, Alexander Moser, Gabriela Studer
The present study aimed to evaluate the role of adjuvant radiotherapy (RT) following nipple-sparing mastectomy (NSM) for patients with ductal carcinoma in situ and invasive breast cancer, based on the published literature. Currently, there is no standard for RT following NSM. NSM aims to spare the nipple areola complex (NAC) without compromising locoregional control. Long-term follow-up studies have begun to show promising results. A search of the English literature was performed using the Medline database and Cochrane central library, with the keywords 'nipple/areola-sparing mastectomy', 'whole skin mastectomy' and 'NAC preservation'...
June 2015: Oncology Letters
https://www.readbyqxmd.com/read/26127418/su-e-j-28-gantry-speed-significantly-affects-image-quality-and-imaging-dose-for-4d-cone-beam-computed-tomography-on-the-varian-edge-platform
#17
A Santoso, K Song, S Gardner, I Chetty, N Wen
PURPOSE: 4D-CBCT facilitates assessment of tumor motion at treatment position. We investigated the effect of gantry speed on 4D-CBCT image quality and dose using the Varian Edge On-Board Imager (OBI). METHODS: A thoracic protocol was designed using a 125 kVp spectrum. Image quality parameters were obtained via 4D acquisition using a Catphan phantom with a gating system. A sinusoidal waveform was executed with a five second period and superior-inferior motion. 4D-CBCT scans were sorted into 4 and 10 phases...
June 2015: Medical Physics
https://www.readbyqxmd.com/read/26096694/radiofrequency-ablation-of-stage-ia-non-small-cell-lung-cancer-in-medically-inoperable-patients-results-from-the-american-college-of-surgeons-oncology-group-z4033-alliance-trial
#18
MULTICENTER STUDY
Damian E Dupuy, Hiran C Fernando, Shauna Hillman, Thomas Ng, Angelina D Tan, Amita Sharma, William S Rilling, Kelvin Hong, Joe B Putnam
BACKGROUND: This study evaluated the 2-year overall survival rate, adverse event rate, local control rate, and impact on pulmonary function tests for medically inoperable patients with stage IA non-small cell lung cancer (NSCLC) undergoing computed tomography (CT)-guided radiofrequency ablation (RFA) in a prospective, multicenter trial. METHODS: Fifty-four patients (25 men and 29 women) with a median age of 76 years (range, 60-89 years) were enrolled from 16 US centers; 51 patients were eligible for evaluation (they had biopsy-proven stage IA NSCLC and were deemed medically inoperable by a board-certified thoracic surgeon)...
October 1, 2015: Cancer
https://www.readbyqxmd.com/read/26053310/advanced-high-grade-serous-ovarian-cancer-frequency-and-timing-of-thoracic-metastases-and-the-implications-for-chest-imaging-follow-up
#19
Atul B Shinagare, Ailbhe C O'Neill, SuChun Cheng, Bhanusupriya Somarouthu, Sree H Tirumani, Mizuki Nishino, Annick D Van den Abbeele, Nikhil H Ramaiya
PURPOSE: To study the frequency, timing, and associations of thoracic metastases in advanced (stage III and IV) high-grade serous ovarian cancer (HGSC) to help optimize the use of cross-sectional chest imaging. MATERIALS AND METHODS: This institutional review board-approved retrospective study with waived informed consent included 186 consecutive patients with pathologically proven advanced HGSC after primary cytoreduction (mean age ± standard deviation, 60 years ± 9...
December 2015: Radiology
https://www.readbyqxmd.com/read/25930161/safety-and-diagnostic-performance-of-image-guided-lung-biopsy-in-the-targeted-therapy-era
#20
Marco Busso, Diego Sardo, Irene Garetto, Luisella Righi, Giulia Libero, Tiziana Vavalà, Francesco Ardissone, Silvia Novello, Mauro Papotti, Andrea Veltri
OBJECTIVE OF THE STUDY: To identify risk factors for the adverse events and determine the diagnostic yield of a large series of image-guided thoracic biopsies performed in a single institution. MATERIALS AND METHODS: We reviewed a consecutive series of 811 patients (546 males; average age: 68 years.) who underwent 824 image-guided biopsies of pulmonary lesions performed between 2009 and 2013. Indications for biopsy were always evaluated by a multidisciplinary board...
November 2015: La Radiologia Medica
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