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https://www.readbyqxmd.com/read/28449533/can-mathematics-replace-anatomy-to-establish-recommendations-in-lung-cancer-surgery
#1
EDITORIAL
Marc Riquet, Ciprian Pricopi, Antoine Legras, Alex Arame, Alain Badia, Françoise Le Pimpec Barthes
The greater the number of lymph node (LN) sampled (NLNsS) during lung cancer surgery, the lower the risk of underestimating the pN-status and the better the outcome of the pN0-patients due to stage-migration. Thus, regarding LN sampling "to be or not to be", number is the question. Recent studies advocate removing 10 LNs. The most suitable NLNsS is unfortunately impossible to establish by mathematics. A too high NLNsS variability exists, based on anatomy, surgery and pathology. The methodology may vary according to Inter-institutional differences in the surgical approach regarding LN inspection and number sampling...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449508/avoiding-completion-pneumonectomy-by-omentopexy-for-bronchial-dehiscence
#2
Takuro Miyazaki, Naoya Yamasaki, Tomoshi Tsuchiya, Keitaro Matsumoto, Ryotaro Kamohara, Go Hatachi, Shigekazu Hidaka, Takeshi Nagayasu
A 56-year-old man underwent right upper sleeve lobectomy with mediastinal lymph node dissection after induction chemoradiotherapy (CRT) for advanced non-small cell lung cancer (NSCLC). The patient developed anastomotic dehiscence 11 days postoperatively. A fistula measuring 10 mm in diameter was found around the transition region between cartilage and membranous portions of the bronchus. To avoid completion right pneumonectomy, omentopexy was performed to cover the bronchial dehiscence and facilitate healing...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449507/primary-mediastinal-myelolipoma-a-case-report-and-literature-review
#3
Qingtong Shi, Shu Pan, Yang Bao, Huangxin Fan, Yali Diao
Myelolipoma is a kind of rare benign tumour composed of mature adipocytes and hemopoietic elements, and is most often found in the adrenal glands. Primary mediastinal myelolipoma (PMM) more rarely happens and has no definite symptoms, and mediastinal masses are usually found in chest examination. The patients normally receive a surgical resection and have a favorable prognosis after postoperative pathological diagnosis. Here, we present the case of PMM, which was resected via video-assisted thoracic surgery (VATS), and investigate recent correlative literatures to summarize its etiology, histopathology, differential diagnosis and therapeutic method...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449480/reconstruction-of-mediastinal-vessels-for-invasive-thymoma-a-retrospective-analysis-of-25-cases
#4
Yifeng Sun, Chang Gu, Jianxin Shi, Wentao Fang, Qingquan Luo, Dingzhong Hu, Shijie Fu, Xufeng Pan, Yong Chen, Yu Yang, Haitang Yang, Heng Zhao, Haiquan Chen
BACKGROUND: Discuss an appropriate strategy for treatment of invasive thymoma invading adjacent great vessels. METHODS: A retrospective study on 25 patients with invasive thymoma invading neighboring great vessels was performed. The corresponding data including clinical presentation, operation procedure, adjuvant radio-chemotherapy and follow-up were reviewed. RESULTS: Twenty of 25 (80%) patients with invasive thymoma underwent complete resection of the tumor along with vessel reconstruction...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449474/impact-of-lymph-node-management-on-resectable-non-small-cell-lung-cancer-patients
#5
Apichat Tantraworasin, Somcharoen Saeteng, Sophon Siwachat, Tawatchai Jiarawasupornchai, Nirush Lertprasertsuke, Sarawut Kongkarnka, Chidchanok Ruengorn, Jayanton Patumanond, Emanuela Taioli, Raja M Flores
BACKGROUND: A surgical lung resection with systematic mediastinal lymph node (LN) dissection is recommended by the National Comprehensive Cancer Network guideline. However, the effective number of dissected LNs, stations and positivity is still controversial. The aim of this study is to identify the impact of total numbers, LN stations and positivity of dissected LNs on tumor recurrence and overall death in resectable non-small cell lung cancer (NSCLC). METHODS: This prognostic study used a retrospective data collection design...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28448415/investigation-on-computed-tomography-features-of-primary-thymic-atypical-carcinoid-tumors
#6
Xiaojing Kan, Pengming Wang, Zhiquan Gong, Feifei Gao, Yuxia Zhang, Yinghui Ge
OBJECTIVES: The thymic atypical carcinoid tumors (aTCs) are rare. The computed tomography (CT) features of aTC were poorly studied, and researches under this topic with large samples are in a small quantity in the literature. Our aim was to investigate the CT features of aTC. METHODS: Eleven cases of aTC (7 men and 4 women; mean age, 56 ± 16 years) proved by pathology were retrospectively analyzed. All the patients underwent contrast-enhanced CT scans with dual phase (25-30 and 60-70 seconds) after contrast agent injection...
April 26, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28448203/systematic-review-and-meta-analysis-of-randomized-controlled-trials-evaluating-prophylactic-intra-operative-wound-irrigation-for-the-prevention-of-surgical-site-infections
#7
Stijn W de Jonge, Quirine J J Boldingh, Joseph S Solomkin, Benedetta Allegranzi, Matthias Egger, E Patchen Dellinger, Marja A Boermeester
BACKGROUND: Surgical site infections (SSIs) are one of the most common hospital-acquired infections. To reduce SSIs, prophylactic intra-operative wound irrigation (pIOWI) has been advocated, although the results to date are equivocal. To develop recommendations for the new World Health Organization (WHO) SSI prevention guidelines, a systematic literature review and a meta-analysis were conducted on the effectiveness of pIOWI using different agents as a means of reducing SSI. METHODS: The PUBMED, Embase, CENTRAL, CINAHL, and WHO databases were searched...
April 27, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28446984/salvage-surgery-after-high-dose-radiotherapy
#8
REVIEW
Annemie Van Breussegem, Jeroen M Hendriks, Patrick Lauwers, Paul E Van Schil
Salvage surgery is a relatively new entity in thoracic surgery and oncology. Salvage resection after radiotherapy refers to surgery as only remaining therapeutic option in patients who were treated with high-dose stereotactic radiotherapy (SRT) for early-stage lung cancer or full-dose chemoradiation for locally advanced lung cancer. Indications include locally progressive tumors, recurrent local or locoregional disease, or specific complications after radiotherapy such as lung abscesses or infected, necrotic cavities...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28446970/the-role-of-endobronchial-ultrasound-versus-mediastinoscopy-for-non-small-cell-lung-cancer
#9
REVIEW
Katarzyna Czarnecka-Kujawa, Kazuhiro Yasufuku
This review provides an update on the current role of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and mediastinoscopy (Med) in assessment of patients with non-small cell lung cancer (NSCLC). Invasive mediastinal lymph node (LN) staging is the major application for both of these techniques. Up until recently, Med was the gold standard for invasive mediastinal LN staging in NSCLC. However, EBUS-TBNA has shown to be equivalent, and in some studies better than Med for invasive staging of lung cancer...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28445254/the-clinical-features-treatment-and-prognosis-of-primary-mediastinal-malignant-melanoma-a-case-report
#10
ZiHai Li, Hui Jia, Baijiang Zhang, Yongming Zhang, Hui Li, Pingping Song
RATIONALE: Primary malignant melanoma (MM) of the mediastinum is exceedingly rare; a review of the English-language literature reveals only a small number of case reports. In this paper, we discuss a case of primary mediastinal MM and present a review of the relevant literature on its clinical features and treatment. PATIENT CONCERNS: A 52-year-old male presenting with back pain was admitted to our hospital for treatment. Imaging examination revealed an anterior mediastinal mass and no evidence of other metastatic or primary lesions...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28442374/peritonsillar-and-deep-neck-infections-a-review-of-330-cases
#11
Paula Martínez Pascual, Paloma Pinacho Martinez, Eviatar Friedlander, Carlos Martin Oviedo, Bartolome Scola Yurrita
INTRODUCTION: Deep neck infections (DNI) are defined as suppurative infectious processes of deep visceral spaces of the neck. OBJECTIVE: The aim of this study is to review different factors that may influence peritonsillar and deep neck Infections (DNI) and may play a role as bad prognosis predictors. METHODS: We present a retrospective study of 330 patients with DNI and peritonsillar infections who were admitted between January 2005 and December 2015 in a tertiary referral hospital...
April 9, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28441913/the-masquerading-presentation-of-a-systemic-anaplastic-large-cell-lymphoma-alk-positive-a-case-report-and-review-of-the-literature
#12
Selma Al-Ahmad, Vincent Maertens, Christophe Libeer, Vera Schelfhout, Filip Vanhoenacker, Nancy Boeckx, Marleen Vandevenne
We report an unusual case of systemic anaplastic large cell lymphoma (ALCL), ALK positive with leukemic involvement in a 57-year-old woman. The patient presented with a fulminant respiratory infection unresponsive to treatment requiring intensive care and ventilatory support. The CT scan demonstrated mediastinal and bilateral lymphadenopathy. On peripheral smear a few atypical lymphocytes were visualized. Based on the increasing number of atypical lymphocytes in the daily peripheral bloodsmears, the diagnosis ALCL was suggested...
April 25, 2017: Acta Clinica Belgica
https://www.readbyqxmd.com/read/28441828/-clinical-analysis-of-seven-cases-of-pulmonary-malignant-tumors-in-children
#13
D Xu, Z M Chen, W Z Gu, Y S Wang, M X Huang, L F Tang, Y Y Zhang, Y Jiang
Objective: To understand the clinical manifestation, imaging characteristics and outcomes of pulmonary malignant tumors in children. Method: We retrospectively collected information about seven cases of pulmonary malignant tumors in children in our hospital from Jan 2010 to Dec 2016. The information included clinical manifestation, imaging characteristics, pathologic results, and treatment. Result: (1) All the seven patients firstly visited pediatric internal medicine departments. Symptoms included cough (n=6), dyspnea (n=4), fever (n=2), anorexia (n=2), chest tightness (n=1), chest pain (n=1), lameness (n=1), abdominal distension and constipation (n=1)...
April 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28441376/nut-midline-carcinoma-a-rare-malignancy
#14
Sameer Al Diffalha, Nidal Al Aukla, Saleh Hasan, Shohreh Dickinson, Farah Khalil
Nuclear protein of the testis (NUT) midline carcinoma can present in the head, neck, and mediastinum. In general, it presents in young adult men and has a poor prognosis. We report on a case of NUT midline carcinoma of the mediastinum in a man 27 years of age without any prior malignancy. Due to the location of the tumor, mediastinal lymphoma and germ cell tumor were initially considered; however, immunohistochemistry was performed using NUT antibody that revealed it to be NUT midline carcinoma. Although guidelines exist for squamous cell carcinoma of the head, neck, and mediastinum, no such specific guidelines are available for NUT midline carcinoma, which looks morphologically similar to squamous cell carcinoma but behaves more aggressively and carries a poor prognosis...
April 2017: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/28440914/transesophageal-bronchoscopic-ultrasound-guided-fine-needle-aspiration-eus-b-fna-pushing-the-boundaries-in-the-diagnosis
#15
Ravindra Mehta, Pavan Biraris, Swarna Shivakumar, Seema Misra, Parameswaran Anoop, Srikanta J T
Isolated mediastinal adenopathy is a diagnostic challenge in the paediatric population, often requiring invasive surgical procedures for diagnosis. We describe a novel minimally invasive modality in a 20 month toddler-transesophageal bronchoscopic ultrasound-guided fine-needle aspiration (EUS-B-FNA). This is the youngest reported use of this modality, highlighting feasibility, technical issues, safety, and rapid diagnosis leading to expedited treatment.
April 25, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28440847/diafragmabr%C3%A3-ck-ledde-till-kolonileus-med-sekund%C3%A3-r-mediastinal-%C3%A3-verskjutning-ovanligt-fall-visar-att-hiatusbr%C3%A3-ck-m%C3%A3-ste-tas-p%C3%A3-allvar
#16
Victor Mill, Claes Brodin
Large bowel obstruction with effects on the mediastinum We present a patient in which the colon and left kidney herniated through a left-sided diaphragmatic hernia. The cause of the hernia was unknown, although most likely it emanated from an earlier diaphragmatic rupture caused by trauma. Due to a diverticular stenosis of the sigmoid colon, the patient developed large bowel obstruction, causing displacement of mediastinal structures. Emergency laparotomy and anterolateral thoracotomy was performed.
April 19, 2017: Läkartidningen
https://www.readbyqxmd.com/read/28440606/pathogenesis-and-prevention-of-radiation-induced-myocardial-fibrosis
#17
Li Kun Liu, Weiwei Ouyang, Xing Zhao, Sheng Fa Su, Yan Yang, Wen Jin Ding, Da Xian Luo, Zhi Xu He, Bing Lu
Radiation therapy is one of the most important methods for the treatment of malignant tumors. However, in radiotherapy for thoracic tumors such as breast cancer, lung cancer, esophageal cancer, and mediastinal lymphoma, the heart, located in the mediastinum, is inevitably affected by the irradiation, leading to pericardial disease, myocardial fibrosis, coronary artery disease, valvular lesions, and cardiac conduction system injury, which are considered radiation-induced heart diseases. Delayed cardiac injury especially myocardial fibrosis is more prominent, and its incidence is as high as 20–80%...
March 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28440531/initial-polish-experience-of-flexible-19-gauge-endobronchial-ultrasound-guided-transbronchial-needle-aspiration
#18
Maciej Gnass, Joanna Sola, Anna Filarecka, Stanisław Orzechowski, Piotr Kocoń, Monika Pasieka-Lis, Juliusz Pankowski, Lucyna Rudnicka, Jerzy Soja, Artur Szlubowski
INTRODUCTION: EBUS is a well established minimally invasive diagnostic tool for mediastinal and hilar lymphadenopathy. The novel ViziShot Flex 19G needle (Olympus Respiratory America, Redmond, WA, USA) was introduced in 2015 in order to improve loaded scope flexion and to obtain larger tissue samples for analysis. The aims of this study were to assess diagnostic yield of Flex 19G needles and to present endoscopist's feedback about the endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA)...
2017: Advances in Respiratory Medicine
https://www.readbyqxmd.com/read/28439321/embolization-of-a-bronchial-artery-aneurysm-in-a-chronic-obstructive-pulmonary-disease-copd-patient-with-non-massive-hemoptysis
#19
Ignazio Salamone, Marco Cavallaro, Carmela Visalli, Mariano Velo, Ugo Barbaro, Karol Galletta, Filippo Andò
BACKGROUND: Bronchial artery aneurysm (BAA) is a rare condition with a reported prevalence of less than 1% of all selective bronchial arterial angiograms. Despite its low incidence, BAA represents a potential cause of hemoptysis. CASE REPORT: We describe the case of a 63-year-old man suffering from chronic obstructive pulmonary disease (COPD), who presented with non-massive hemoptysis. CT angiography revealed a single bronchial artery aneurysm of 9 mm in diameter, abutting the esophageal wall...
2017: Polish Journal of Radiology
https://www.readbyqxmd.com/read/28438507/cardiothoracic-transplant-recipient-mycoplasma-hominis-an-uncommon-infection-with-probable-donor-transmission
#20
Rahul Sampath, Robin Patel, Scott A Cunningham, Sana Arif, Richard C Daly, Andrew D Badley, Mark E Wylam
The role of infection with Mycoplasma hominis following cardiothoracic organ transplantation and its source of transmission have not been well-defined. Here, we identify and describe infection with M. hominis in patients following cardiothoracic organ transplantation after reviewing all cardiothoracic transplantations performed at our center between 1998 and July 2015. We found seven previously unreported cases of M. hominis culture positive infection all of whom presented with pleuritis, surgical site infection, and/or mediastinitis...
April 19, 2017: EBioMedicine
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