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Inadequate pain

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https://www.readbyqxmd.com/read/29779794/understanding-pain-and-pain-management-in-elderly-nursing-home-patients-applying-an-interprofessional-learning-activity-in-health-care-students-a-norwegian-pilot-study
#1
Elin Damsgård, Hege Solgård, Karin Johannessen, Katrine Wennevold, Gunnvald Kvarstein, Gunn Pettersen, Beate Garcia
Pain is common among elderly patients in nursing homes. However, pain assessment and treatment are inadequate. Interprofessional treatment is recommended, and consequently interprofessional education in pain management is necessary. This pilot project aimed to describe how two interprofessional groups of students approached pain management in two nursing home patients. We formed two teams comprising one student from the nursing, physical therapy, pharmacy, and medical educations. Each team spent one day examining a patient with chronic pain at a nursing home and they developed pain management plans...
May 17, 2018: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
https://www.readbyqxmd.com/read/29778756/nurses-knowledge-attitudes-and-clinical-practice-in-pediatric-postoperative-pain-management
#2
Anja Hetland Smeland, Alison Twycross, Stefan Lundeberg, Tone Rustøen
Despite readily available evidence to guide practice, children continue to experience moderate to severe pain in hospital postoperatively. Reasons for this may include attitudes of nurses toward pain management and their lack of knowledge in key areas. To identify nurses' knowledge and clinical practice of pediatric postoperative pain management and whether there is a link between knowledge and practice. A descriptive cross-sectional study including a questionnaire and observations was conducted in postanesthesia care (recovery) units in six university hospitals in Norway...
May 16, 2018: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
https://www.readbyqxmd.com/read/29776706/gaps-in-pain-agitation-and-delirium-management-in-intensive-care-outputs-from-a-nurse-workshop
#3
REVIEW
Carsten Hermes, Maria Acevedo-Nuevo, Andrea Berry, Thomas Kjellgren, Alessandra Negro, Paola Massarotto
Significant improvements in our understanding of pain, agitation, and delirium management within the Intensive Care Unit have been made in recent years. International guidelines and implementation bundles have become more evidence-based, patient-centred, and provide clear recommendations on the best-practice management of critically ill patients. However, the intensive care community has highlighted the need for higher-order evidence in several areas of pain, agitation and delirium research and studies suggest that a significant number of intensive care patients still receive outdated treatment as a consequence of inadequate guideline implementation...
May 15, 2018: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/29775691/pain-in-maintenance-hemodialysis-patients-a-multicenter-study
#4
Tatiana Talya Fleishman, Jacob Dreiher, Pesach Shvartman
CONTEXT: Pain is a common complaint in maintenance hemodialysis (MHD) patients, yet is often inadequately assessed and undertreated. OBJECTIVES: To evaluate the prevalence, characteristics, intensity, and impact of pain in MHD patients. METHODS: In a cross-sectional study conducted between 2013 and 2015, 336 MHD patients from five hemodialysis units in hospitals owned by Clalit were interviewed and evaluated. Study tools included the Brief Pain Inventory, The Leeds Assessment of Neuropathic Symptoms and Signs pain scale, demographic and clinical characteristics...
May 15, 2018: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29773353/nurses-knowledge-and-attitudes-regarding-pediatric-pain-management-in-western-australia
#5
Deborah Peirce, Victoria Corkish, Margie Lane, Sally Wilson
Despite clinical guidelines, suboptimal pediatric pain management persists. A local audit found poor guideline compliance. Inadequate knowledge is a recognized barrier to the delivery of evidence-based care. The aim of the study was to investigate nurses' knowledge and attitudes regarding pain management at an Australian tertiary pediatric hospital. A cross-sectional, descriptive study using the Pediatric Pain Knowledge and Attitudes Questionnaire (Revised) was distributed to 590 nurses in an Australian pediatric hospital...
May 14, 2018: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
https://www.readbyqxmd.com/read/29772922/behavioral-pain-intervention-for-hospice-and-palliative-care-patients-an-integrative-review
#6
Masako Mayahara, JoEllen Wilbur, Louis Fogg, Susan M Breitenstein
Despite the advances in pain management, achieving optimal pain control in hospice and palliative care is challenging. Patient/caregiver's lack of pain management knowledge, poor pain reporting, and poor adherence to pain management regimens are all associated with inadequate pain control. The purpose of this integrated review is to examine behavioral interventions designed for patients and caregivers to improve pain control in hospice and palliative care settings. Ten studies were identified through a database search...
January 1, 2018: American Journal of Hospice & Palliative Care
https://www.readbyqxmd.com/read/29766827/pain-related-behavior-and-brain-activation-in-a-cynomolgus-macaque-model-of-postoperative-pain
#7
Aldric Hama, Takahiro Natsume, Shin'ya Ogawa, Yūji Awaga, Ikuo Hayashi, Akihisa Matsuda, Hiroyuki Takamatsu
BACKGROUND: Inadequate postoperative pain management could lead to persistent pain and this is, in part, due to incomplete understanding of the mechanism of postoperative pain. Currently available rodent models may have limited translatability to clinical postoperative pain. Thus, a preclinical model of postoperative pain was developed in the cynomolgus macaque, a species that is phylogenetically closer to humans than rodents. METHOD: The presence of pressure hypersensitivity was assessed with non-noxious pressure applied proximally and distally (approximately 10 cm) to an abdominal incision in macaques...
May 15, 2018: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/29764442/cross-cultural-adaptation-validity-and-reliability-of-the-persian-version-of-the-spine-functional-index
#8
Hamid Reza Mokhtarinia, Azadeh Hosseini, Azam Maleki-Ghahfarokhi, Charles Philip Gabel, Majid Zohrabi
BACKGROUND: There are various instruments and methods to evaluate spinal health and functional status. Whole-spine patient reported outcome (PRO) measures, such as the Spine Functional Index (SFI), assess the spine from the cervical to lumbo-sacral sections as a single kinetic chain. The aim of this study was to cross-culturally adapt the SFI for Persian speaking patients (SFI-Pr) and determine the psychometric properties of reliability and validity (convergent and construct) in a Persian patient population...
May 15, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29763832/the-impact-of-a-pain-assessment-intervention-on-pain-score-and-analgesic-use-in-older-nursing-home-residents-with-severe-dementia-a-cluster-randomised-controlled-trial
#9
Hanne Marie Rostad, Inger Utne, Ellen Karine Grov, Milada Cvancarova Småstuen, Martine Puts, Liv Halvorsrud
BACKGROUND: Pain is highly prevalent in older adults, especially those in institutional settings such as nursing homes. The presence of dementia may increase the risk of underdiagnosed and undertreated pain. Pain assessment tools are not regularly used in clinical practice, however, there are indications that the regular use of pain assessments tools may influence the recognition of pain by nursing staff and thereby affect pain management. OBJECTIVES: To assess whether regular pain assessment using a pain assessment tool is associated with changes in i) pain scores and ii) analgesic use in nursing home residents with severe dementia...
April 30, 2018: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29761830/itc-commentary-on-metformin-clinical-drug-drug-interaction-study-design-that-enables-an-efficacy-and-safety-based-dose-adjustment-decision
#10
Maciej J Zamek-Gliszczynski, Xiaoyan Chu, Jack A Cook, Joseph M Custodio, Aleksandra Galetin, Kathleen M Giacomini, Caroline A Lee, Mary F Paine, Adrian S Ray, Joseph A Ware, Matthias B Wittwer, Lei Zhang
Metformin drug-drug interaction (DDI) studies are conducted during development of drugs that inhibit organic cation transporters and/or multidrug and toxin extrusion proteins (OCTs/MATEs). Monitoring solely changes in systemic exposure, the typical DDI study endpoint appears inadequate for metformin, which is metabolically stable, has poor passive membrane permeability, and undergoes transporter-mediated tissue distribution and clearance. Evaluation of renal clearance, antihyperglycemic effects, and potentially lactate as an exploratory safety marker, can support rational metformin dose adjustment...
May 15, 2018: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29750315/mobilization-with-movement-and-kinesio-taping-in-knee-arthritis-evaluation-and-outcomes
#11
Hülya Altmış, Deran Oskay, Bülent Elbasan, İrem Düzgün, Zeynep Tuna
INTRODUCTION: The aim of this study was to investigate the acute effects of Mulligan mobilization with movement (MwM) and taping on function and pain intensity in patients with osteoarthritis (OA). MATERIALS AND METHODS: Female patients aged between 40 and 70 years with knee OA participated in the study. The patients were divided into three groups and each group received different interventions. Group 1 received MwM and taping according to Mulligan's concept. Group 2 received MwM and placebo taping with no recovery effect and group 3 received placebo taping...
May 10, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29735382/evidence-based-nonpharmacologic-strategies-for-comprehensive-pain-care-the-consortium-pain-task-force-white-paper
#12
Heather Tick, Arya Nielsen, Kenneth R Pelletier, Robert Bonakdar, Samantha Simmons, Ronald Glick, Emily Ratner, Russell L Lemmon, Peter Wayne, Veronica Zador
Consortium Pain Taskforce White Paper Summary Evidence-based Nonpharmacologic Strategies for Comprehensive Pain Care Supplementary information can be found in the online version at https://doi.org/10.1016/j.explore.2018.02.001. Medical pain management is in crisis; from the pervasiveness of pain to inadequate pain treatment, from the escalation of prescription opioids to an epidemic in addiction, diversion and overdose deaths. The rising costs of pain care and managing adverse effects of that care have prompted action from state and federal agencies including the DOD, VHA, NIH, FDA and CDC...
March 1, 2018: Explore: the Journal of Science and Healing
https://www.readbyqxmd.com/read/29732985/treatment-of-chronic-articular-pain-in-adults-with-hemophilia
#13
E Carlos Rodriguez-Merchan
INTRODUCTION: Adult people with hemophilia (PWH) mainly use Factor VIII/Factor IX (FVIII/FIX) to lessen chronic articular pain, followed in frequency by nonsteroidal anti-inflammatory drugs. Analgesics are used by only one-third of adult PWH. Limitations in activities of daily living are encountered in the large majority of PWH, and most describe pain as affecting their state of mind. A review of the literature on their treatment is important because chronic pain in adult PWH is often undertreated or wrongly treated, causing psychological problems for these patients...
May 3, 2018: Cardiovascular & Hematological Disorders Drug Targets
https://www.readbyqxmd.com/read/29729774/complex-cancer-pain-assessment
#14
REVIEW
Regina M Fink, Jeannine M Brant
Pain is widespread, multidimensional, and one of the most distressing symptoms patients with cancer face. Pain assessment is the foundation to optimal pain management. Despite evidence-based practice guidelines, inadequate pain assessment is a barrier. Patients should be routinely screened for pain at each encounter. If new, worsening, or persistent pain is present, a comprehensive pain assessment and reassessment should be regularly performed and documented to communicate the pain problem. Patient self-report of pain is the gold standard even in those who are nonverbal or cognitively impaired...
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29722912/region-specific-deletions-of-the-glutamate-transporter-glt1-differentially-affect-nerve-injury-induced-neuropathic-pain-in-mice
#15
Zhuoyang Zhao, Yuichi Hiraoka, Hiroshi Ogawa, Kohichi Tanaka
Glutamate is a major excitatory neurotransmitter and plays an important role in neuropathic pain, which is frequently caused by nerve damage. According to recent studies, nerve injury induces changes in glutamatergic transmission in the spinal cord and several supraspinal regions, including the periaqueductal gray (PAG). Among glutamate signaling components, accumulating evidence suggests that the glial glutamate transporter GLT1 plays a critical role in neuropathic pain. Indeed, GLT1 expression is reduced in the spinal cord but increased in the PAG after nerve injury, suggesting that the role of GLT1 in neuropathic pain may vary according to the brain region...
May 3, 2018: Glia
https://www.readbyqxmd.com/read/29722031/indirect-acting-strategy-of-opioid-action-instead-of-direct-receptor-activation-dual-acting-enkephalinase-inhibitors-denkis
#16
REVIEW
R B Raffa, J V Pergolizzi, R Taylor, M H Ossipov
WHAT IS KNOWN AND OBJECTIVE: Although pain is one of the most common afflictions, it is often inadequately managed because the available analgesic options are relatively limited due to insufficient efficacy, unacceptable adverse effects or the potential for misuse or abuse. However, recent publications suggest that an alternative approach-indirect enhancement of endogenous pain-relieving pathways-might be desirable. We review this approach, in particular the dual enkephalinase inhibitors (DENKIs)...
May 2, 2018: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/29720267/efficacy-of-postoperative-pain-management-in-head-and-neck-cancer-patients
#17
Ashley Hinther, Steven C Nakoneshny, Shamir P Chandarana, T Wayne Matthews, Joseph C Dort
BACKGROUND: Our study quantifies the effectiveness of perioperative pain control in a cohort of patients undergoing major head and neck surgery with free flap reconstruction. Our long-term goal is to improve pain control and thereby increase mobility, decrease postoperative complications and decrease hospital stay. METHODS: A retrospective analysis was performed at a tertiary, academic head and neck surgical oncology program in Calgary, Alberta, Canada from January 1, 2015 - December 31, 2015...
May 2, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29710226/association-between-functional-health-literacy-and-postoperative-recovery-health-care-contacts-and-health-related-quality-of-life-among-patients-undergoing-day-surgery-secondary-analysis-of-a-randomized-clinical-trial
#18
Maria Hälleberg Nyman, Ulrica Nilsson, Karuna Dahlberg, Maria Jaensson
Importance: Day surgery puts demands on the patients to manage their own recovery at home according to given instructions. Low health literacy levels are shown to be associated with poorer health outcomes. Objective: To describe functional health literacy levels among patients in Sweden undergoing day surgery and to describe the association between functional health literacy (FHL) and health care contacts, quality of recovery (SwQoR), and health-related quality of life...
April 25, 2018: JAMA Surgery
https://www.readbyqxmd.com/read/29709457/diabetic-peripheral-neuropathy-epidemiology-diagnosis-and-pharmacotherapy
#19
REVIEW
Zohaib Iqbal, Shazli Azmi, Rahul Yadav, Maryam Ferdousi, Mohit Kumar, Daniel J Cuthbertson, Jonathan Lim, Rayaz A Malik, Uazman Alam
PURPOSE: Diabetic peripheral neuropathy (DPN) is the commonest cause of neuropathy worldwide, and its prevalence increases with the duration of diabetes. It affects approximately half of patients with diabetes. DPN is symmetric and predominantly sensory, starting distally and gradually spreading proximally in a glove-and-stocking distribution. It causes substantial morbidity and is associated with increased mortality. The unrelenting nature of pain in this condition can negatively affect a patient's sleep, mood, and functionality and result in a poor quality of life...
April 27, 2018: Clinical Therapeutics
https://www.readbyqxmd.com/read/29699420/analysis-of-preventability-of-hypertensive-disorder-in-pregnancy-related-maternal-death-using-the-nationwide-registration-system-of-maternal-deaths-in-japan
#20
Shinji Katsuragi, Hiroaki Tanaka, Junichi Hasegawa, Masamitsu Nakamura, Naohiro Kanayama, Masahiko Nakata, Takeshi Murakoshi, Jun Yoshimatsu, Kazuhiro Osato, Kayo Tanaka, Akihiko Sekizawa, Isamu Ishiwata, Tomoaki Ikeda
OBJECTIVE: Hypertensive disorder of pregnancy (HDP) is a major cause of maternal death. The goal of this study was to investigate factors associated with maternal death due to HDP. STUDY DESIGN: HDP-related maternal deaths in Japan reported to the Committee of the Ministry of Health, Labor and Welfare from 2010 to 2015 were examined. RESULTS: Out of 47 cases of HDP, 30 were identified as the major cause of maternal death. The median maternal age was 34 years (range 24-45) and the mortality in women aged ≥40 years was seven times higher that than in women aged <34 years...
April 26, 2018: Journal of Maternal-fetal & Neonatal Medicine
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