keyword
MENU ▼
Read by QxMD icon Read
search

Stress-related

keyword
https://www.readbyqxmd.com/read/28636950/structural-evidence-of-quercetin-multi-target-bioactivity-a-reverse-virtual-screening-strategy
#1
Diego Carvalho, Margot Paulino, Fabio Polticelli, Florencia Arredondo, Robert J Williams, Juan A Abin-Carriquiry
The ubiquitous flavonoid quercetin is broadly recognized for showing diverse biological and health-promoting effects, such as anti-cancer, anti-inflammatory and cytoprotective activities. The therapeutic potential of quercetin and similar compounds for preventing such diverse oxidative stress-related pathologies has been generally attributed to their direct antioxidant properties. Nevertheless, accumulated evidence indicates that quercetin is also able to interact with multiple cellular targets influencing the activity of diverse signaling pathways...
June 18, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28634520/effect-of-heartfulness-meditation-on-burnout-emotional-wellness-and-telomere-length-in-health-care-professionals
#2
Jayaram Thimmapuram, Robert Pargament, Kedesha Sibliss, Rodney Grim, Rosana Risques, Erik Toorens
Background: Burnout poses significant challenges during training years in residency and later in the career. Meditation is a tool to treat stress-related conditions and promote wellness. Telomere length may be affected by burnout and stress. However, the benefits of meditation have not been fully demonstrated in health care professionals. Objective: We assessed the effects of a 12-week 'Heartfulness Meditation' program on burnout, emotional wellness, and telomere length in residents, faculty members, and nurses at a large community teaching hospital during the 2015-16 academic year...
January 2017: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/28633353/modulating-role-of-ros-in-re-establishing-desiccation-tolerance-in-germinating-seeds-of-caragana-korshinskii-kom
#3
Long Peng, Sirui Lang, Yu Wang, Hugh W Pritchard, Xiaofeng Wang
In close agreement with visible germination, orthodox seeds lose desiccation tolerance (DT). This trait can be regained under osmotic stress, but the mechanisms are poorly understood. In this study, germinating seeds of Caragana korshinskii Kom. were investigated, focusing on the potential modulating roles of reactive oxygen species (ROS) in the re-establishment of DT. Germinating seeds with 2 mm long radicles can be rendered tolerant to desiccation by incubation in a polyethylene glycol (PEG) solution (-1...
June 15, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28631572/endoplasmic-reticulum-stress-could-induce-autophagy-and-apoptosis-and-enhance-chemotherapy-sensitivity-in-human-esophageal-cancer-ec9706-cells-by-mediating-pi3k-akt-mtor-signaling-pathway
#4
Fang Zhou, Yan-Hua Li, Jian-Jun Wang, Jia Pan, Hong Lu
The study was designed to explore the mechanism of tunicamycin-induced endoplasmic reticulum stress in human esophageal cancer EC9706 cells and EC109 cells, as well as its effects on cell autophagy, apoptosis, and chemoresistance. Tunicamycin-induced endoplasmic reticulum stress model was established in EC9706 and EC109 cell lines. Western blotting was employed to detect the expression of endoplasmic reticulum stress iconic protein GRP78. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay was used to evaluate the effect of different cisplatin and tunicamycin concentrations on survival rate of EC9706 cells and EC109 cells...
June 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28630705/physiological-effects-of-stress-related-to-helicopter-travel-in-federal-emergency-management-agency-search-and-rescue-canines
#5
E Perry, N Gulson, T-W Liu Cross, K S Swanson
Working canines are deployed by the Federal Emergency Management Agency (FEMA), as part of a National Disaster Response Plan. Stress associated with helicopter flight and the resulting physical effects on the dog are unknown. Our objective was to test the hypotheses that (1) helicopter travel affects the physiology and faecal microbiota of working canines, but that (2) physiological consequences of helicopter travel will not negatively affect their work performance. A total of nine FEMA canines were loaded onto helicopters and flown for 30 min in July 2015...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/28629890/perceived-social-stress-and-symptom-severity-among-help-seeking-adolescents-with-versus-without-clinical-high-risk-for-psychosis
#6
Zachary B Millman, Steven C Pitts, Elizabeth Thompson, Emily R Kline, Caroline Demro, Marc J Weintraub, Jordan E DeVylder, Vijay A Mittal, Gloria M Reeves, Jason Schiffman
Research suggests that social stress exposure influences illness presentation and course among youth at clinical high-risk (CHR) for psychosis, though less is known about the extent to which self-reported perceptions of social stress relate to the severity of positive symptoms. Importantly, despite the notion that youth at CHR are especially susceptible to elevations in positive symptoms under conditions of stress, no study has examined this presumption relative to other psychiatric groups. Extending previous work demonstrating that perceived social stress was higher in a CHR group than in a clinical group of non-CHR, help-seeking controls, the current study aimed to: (1) examine whether perceived social stress is related to the severity of attenuated positive symptoms in the full sample (N=110); and (2) determine whether CHR status moderates the stress-symptom relation...
June 16, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28626023/microarray-analysis-of-aging-associated-immune-system-alterations-in-the-rostral-ventrolateral-medulla-of-f344-rats
#7
Sivasai Balivada, Chanran K Ganta, Yongqing Zhang, Hitesh N Pawar, Richard J Ortiz, Kevin G Becker, Arshad M Khan, Michael J Kenney
The rostral ventrolateral medulla (RVLM) is an area of the brainstem that contains diverse neural substrates that are involved in systems critical for physiological function. There is evidence that aging affects some neural substrates within the RVLM, although age-related changes in RVLM molecular mechanisms are not well established. The goal of the present study was to characterize the transcriptomic profile of the aging RVLM and to test the hypothesis that aging is associated with altered gene expression in the RVLM, with an emphasis on immune system associated gene transcripts...
June 16, 2017: Physiological Genomics
https://www.readbyqxmd.com/read/28626004/sex-chromosome-evolution-heterochiasmy-and-physiological-qtl-in-the-salmonid-brook-charr-salvelinus-fontinalis
#8
Ben J G Sutherland, Ciro Rico, Céline Audet, Louis Bernatchez
Whole genome duplication can have large impacts on genome evolution, and much remains unknown about these impacts. This includes the mechanisms of coping with a duplicated sex determination system and whether this has an impact on increasing the diversity of sex determination mechanisms. Other impacts include sexual conflict, where alleles having different optimums in each sex can result in sequestration of genes into non-recombining sex chromosomes. Sex chromosome development itself may involve sex-specific recombination rate (i...
June 16, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28625441/the-protective-effects-of-dexmedetomidine-on-ischemic-brain-injury-a-meta-analysis
#9
REVIEW
Lianxiang Jiang, Meizhu Hu, Yan Lu, Ya Cao, Yan Chang, Zeping Dai
BACKGROUND: Intracranial lesions, trauma or surgery-related damage activate immune inflammation and neuroendocrine responses, causing ischemic brain injury. Studies have shown that inflammatory cascade mediated by neuroendocrine hormones and proinflammatory mediators is implicated in the pathophysiology of ischemic brain injury. Alpha2-adrenoceptor agonists, dexmedetomidine, is widely used as neuroprotectants in anesthesia practice. However, it is still lack of a comprehensive meta-analysis to evaluate the neuroprotection of dexmedetomidine against ischemic brain injury via suppressing these two physiological responses...
August 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28625414/effects-of-health-empowerment-intervention-on-resilience-of-adolescents-in-a-tribal-area-a-study-using-the-solomon-four-groups-design
#10
Kaushik Sarkar, Aparajita Dasgupta, Multipada Sinha, Bhaskar Shahbabu
RATIONALE: Resilience prevents the emergence of stress-related mental health problems among adolescents. Adolescents in tribal areas of India are more prone to develop such problems. OBJECTIVES: The primary objective was to determine the effect of combined life skills-based health empowerment intervention on the resilience of school-going adolescents in a tribal area. The secondary objectives were to determine the effect of the intervention on internal health locus of control and self-determination and to compare the effect of intervention on resilience between non-tribal and tribal adolescents...
June 12, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28624572/role-of-beta-catenin-and-endocannabinoids-in-the-nucleus-accumbens-in-extinction-in-rats-exposed-to-shock-and-reminders
#11
Nachshon Korem, Rachel Lange, Cecilia J Hillard, Irit Akirav
The response to a traumatic experience may be rapid recovery or development of psychopathology such as posttraumatic stress disorder (PTSD). Impaired extinction of fear memories is thought to contribute to the development of the persistent trauma memories and avoidance. The Wnt/β-catenin pathway and the endocannabinoid system appear to play significant roles in anxiety and depressive symptoms. Here we examined the involvement of β-catenin in the nucleus accumbens (NAc) in extinction in rats exposed to the shock and reminders model of PTSD...
June 14, 2017: Neuroscience
https://www.readbyqxmd.com/read/28624198/emerging-roles-of-circrna-related-to-the-mechanical-stress-in-human-cartilage-degradation-of-osteoarthritis
#12
Qiang Liu, Xin Zhang, Xiaoqing Hu, Lan Yuan, Jin Cheng, Yanfang Jiang, Yingfang Ao
Circular RNAs (circRNAs) are involved in the development of various diseases; however, knowledge on circRNAs in osteoarthritis (OA) is limited. This study aims to identify circRNA expression in different regions affected by OA and to explore the function of mechanical stress-related circRNAs (circRNAs-MSR) in cartilage. Bioinformatics was employed to predict the interaction of circRNAs and mRNAs in the cartilage. Loss-of-function experiments for circRNAs-MSR were performed in vitro. A total of 104 circRNAs were differentially expressed in damaged versus intact cartilage...
June 16, 2017: Molecular Therapy. Nucleic Acids
https://www.readbyqxmd.com/read/28622973/maternal-programming-of-sex-specific-responses-to-predator-odor-stress-in-adult-rats
#13
Sophie St-Cyr, Sameera Abuaish, Shathveekan Sivanathan, Patrick O McGowan
Prenatal stress mediated through the mother can lead to long-term adaptations in stress-related phenotypes in offspring. This study tested the long-lasting effect of prenatal exposure to predator odor, an ethologically relevant and psychogenic stressor, in the second half of pregnancy. As adults, the offspring of predator odor-exposed mothers showed increased anxiety-like behaviors in commonly used laboratory tasks assessing novelty-induced anxiety, increased defensive behavior in males and increased ACTH stress reactivity in females in response to predator odor...
June 13, 2017: Hormones and Behavior
https://www.readbyqxmd.com/read/28620285/the-evidence-for-altered-bdnf-expression-in-the-brain-of-rats-reared-or-housed-in-social-isolation-a-systematic-review
#14
REVIEW
Jana Murínová, Nataša Hlaváčová, Magdaléna Chmelová, Igor Riečanský
There is evidence that development and maintenance of neural connections are disrupted in major mental disorders, which indicates that neurotrophic factors could play a critical role in their pathogenesis. Stress is a well-established risk factor for psychopathology and recent research suggests that disrupted signaling via brain-derived neurotrophic factor (BDNF) may be involved in mediating the negative effects of stress on the brain. Social isolation of rats elicits chronic stress and is widely used as an animal model of mental disorders such as schizophrenia and depression...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28620222/nitric-oxide-mediated-transcriptional-modulation-enhances-plant-adaptive-responses-to-arsenic-stress
#15
Pradyumna Kumar Singh, Yuvraj Indoliya, Abhisekh Singh Chauhan, Surendra Pratap Singh, Amit Pal Singh, Sanjay Dwivedi, Rudra Deo Tripathi, Debasis Chakrabarty
Arsenic (As) contamination in rice leads to yield decline and causes carcinogenic risk to human health. Although the role of nitric oxide (NO) in reducing As toxicity is known, NO-mediated genetic modulation in the plant during arsenic toxicity has not yet been established. We analyzed the key components of NO metabolism and the correlations between NO interaction and arsenic stress using rice as a relevant model plant. Illumina sequencing was used to investigate the NO-mediated genome-wide temporal transcriptomic modulation in rice root upon AsIII exposure during 12 days (d) of the growth period...
June 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28619017/borderline-personality-disorder-and-childhood-trauma-exploring-the-affected-biological-systems-and-mechanisms
#16
Nadia Cattane, Roberta Rossi, Mariangela Lanfredi, Annamaria Cattaneo
BACKGROUND: According to several studies, the onset of the Borderline Personality Disorder (BPD) depends on the combination between genetic and environmental factors (GxE), in particular between biological vulnerabilities and the exposure to traumatic experiences during childhood. We have searched for studies reporting possible alterations in several biological processes and brain morphological features in relation to childhood trauma experiences and to BPD. We have also looked for epigenetic mechanisms as they could be mediators of the effects of childhood trauma in BPD vulnerability...
June 15, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28618856/psychosocial-stress-and-brain-function-in-adolescent-psychopathology
#17
Erin Burke Quinlan, Anna Cattrell, Tianye Jia, Eric Artiges, Tobias Banaschewski, Gareth Barker, Arun L W Bokde, Uli Bromberg, Christian Büchel, Rüdiger Brühl, Patricia J Conrod, Sylvane Desrivieres, Herta Flor, Vincent Frouin, Jürgen Gallinat, Hugh Garavan, Penny Gowland, Andreas Heinz, Jean-Luc Martinot, Marie-Laure Paillère Martinot, Frauke Nees, Dimitri Papadopoulos-Orfanos, Tomáš Paus, Luise Poustka, Michael N Smolka, Nora C Vetter, Henrik Walter, Robert Whelan, Jeffrey C Glennon, Jan K Buitelaar, Francesca Happé, Eva Loth, Edward D Barker, Gunter Schumann
OBJECTIVE: The authors sought to explore how conduct, hyperactivity/inattention, and emotional symptoms are associated with neural reactivity to social-emotional stimuli, and the extent to which psychosocial stress modulates these relationships. METHOD: Participants were community adolescents recruited as part of the European IMAGEN study. Bilateral amygdala regions of interest were used to assess the relationship between the three symptom domains and functional MRI neural reactivity during passive viewing of dynamic angry and neutral facial expressions...
June 16, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/28617035/measuring-stress-in-young-children-using-hair-cortisol-the-state-of-the-science
#18
Randi Bates, Pamela Salsberry, Jodi Ford
Extensive literature suggests that adverse experiences in early childhood may deleteriously impact later health. These effects are thought to be related to the impact of persistent or chronic stress on various biological processes, mediated by dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, and ultimately irregularities in cortisol levels. Ameliorating persistent stress in young children requires accurately measuring the chronicity of physiologic stress, which is difficult in young children because of unreliable self-report and the burden and inaccuracy associated with using invasive acute-stress biomeasures...
January 1, 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28617017/identifying-trajectories-of-change-to-improve-understanding-of-integrated-health-care-outcomes-on-ptsd-symptoms-post-disaster
#19
Howard J Osofsky, Carl F Weems, Tonya Cross Hansel, Anthony H Speier, Joy D Osofsky, Rebecca Graham, Lucy King, Timothy K Craft
INTRODUCTION: Addressing life stressors is an important function for integrated care, especially for health care homes located in disaster prone environments. This study evaluated trajectories of change for patients with postdisaster posttraumatic stress disorder (PTSD) who were seen in integrated care. In addition to describing the results, this article provides the methods of subgroup analyses as this may be useful for others working in real-world practice. METHOD: Patients (N = 340) receiving services at 5 rural health clinics self-reported PTSD symptoms as part of an ongoing evaluation to study the effectiveness of integrated health...
June 2017: Families, Systems & Health: the Journal of Collaborative Family Healthcare
https://www.readbyqxmd.com/read/28616995/the-hippocampus-and-the-regulation-of-human-food-intake
#20
Richard J Stevenson, Heather M Francis
Human and animal data suggest that the hippocampus plays certain roles in regulating food intake. However, its actual role may be far broader than currently envisaged, a claim suggested by the centrality of the hippocampus to so many aspects of human/animal cognition. Understanding these ingestion-related functions is especially significant. This is because some degree of hippocampal impairment may be quite common, resulting for example from a Western-style diet, insomnia, diabetes, and depression-among many other causes...
June 15, 2017: Psychological Bulletin
keyword
keyword
75418
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"