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https://www.readbyqxmd.com/read/28644914/the-role-of-expectation-in-multisensory-body-representation-neural-evidence
#1
Francesca Ferri, Ettore Ambrosini, Paola Pinti, Arcangelo Merla, Marcello Costantini
Sensory events contribute to body ownership, the feeling that the body belongs to me. However, the encoding of sensory events is not only reactive, but also proactive in that our brain generates prediction about forthcoming stimuli. In previous studies we have shown that prediction of sensory events is a sufficient condition to induce the sense of body ownership. In this study we investigate the underlying neural mechanisms. Participants were seated with their right arm resting upon a table just below another smaller table...
June 23, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28644568/treatment-of-avoidant-restrictive-food-intake-disorder-in-a-cohort-of-young-patients-in-a-partial-hospitalization-program-for-eating-disorders
#2
Rollyn M Ornstein, Jamal H Essayli, Terri A Nicely, Emily Masciulli, Susan Lane-Loney
OBJECTIVE: Avoidant/restrictive food intake disorder (ARFID) is a recently named condition to classify patients who present with restricted nutritional intake without body image distortion or fear of weight gain. We sought to compare treatment outcomes of patients with ARFID in a family-centered partial hospital program (PHP) to those with other eating disorders (ED). METHODS: A retrospective chart review of 130 patients 7 to 17 years of age admitted to the program from 2008 to 2012 was performed...
June 23, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28644530/long-term-outcome-of-anorexia-nervosa-results-from-a-large-clinical-longitudinal-study
#3
Manfred Maximilian Fichter, Norbert Quadflieg, Ross D Crosby, Sonja Koch
OBJECTIVE: Assessment of the long-term outcome of anorexia nervosa (AN) in a very large sample of inpatients (N = 1,693) and identification of predictors for poor outcome. METHOD: Over 25 years (mean 10 years), consecutively admitted inpatients of a specialized hospital were followed. A subsample of 112 patients with 20-year follow-up was defined. Bivariate comparisons and logistic regression analysis identified risk factors of poor outcome. RESULTS: Body mass index (BMI) increased during the follow-up period...
June 23, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28643289/recovery-from-eating-disorder-1%C3%A2-year-after-start-of-treatment-is-related-to-better-mentalization-and-strong-reduction-of-sensitivity-to-others
#4
Greet S Kuipers, Sandra den Hollander, L Andries van der Ark, Marrie H J Bekker
PURPOSE: To investigate whether recovery from an eating disorder is related to pre-treatment attachment and mentalization and/or to improvement of attachment and mentalization during treatment. METHOD: For a sample of 38 anorexia nervosa (AN) and bulimia nervosa (BN) patients receiving treatment the relations between attachment security, mentalization, comorbidity and recovery status after 12 months (not recovered or recovered), and after 18 months (persistently ill, relapsed, newly recovered, or persistently recovered) were investigated...
June 22, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/28639321/association-of-the-5-ht2a-receptor-gene-promoter-polymorphism-1438g-a-with-anorexia-nervosa-and-psychopathological-traits-in-the-chinese-han-population-a-preliminary-study
#5
Qing Kang, Jue Chen, Shunying Yu, Aihua Yuan, Yanxia Zhang, Ran Zhang, Wenhui Jiang, Chen Zhang, Haiyin Zhang, Mingdao Zhang, Zeping Xiao
OBJECTIVE: The aim of the study was to explore the possible role of the 5-HT2A -1438G/A polymorphism in the susceptibility to anorexia nervosa (AN) in the Chinese Han population. METHODS: The -1438G/A polymorphism of 249 female AN patients, 228 matched healthy controls, and 198 trios was genotyped using SNaP shot assay. Psychopathological traits of eating-disordered behaviors in AN subjects were examined using the Chinese version of the Eating Disorder Examination Questionnaire...
June 22, 2017: Asia-Pacific Psychiatry: Official Journal of the Pacific Rim College of Psychiatrists
https://www.readbyqxmd.com/read/28639048/evaluating-anorexia-related-brain-atrophy-using-mp2rage-based-morphometry
#6
José Boto, Georgios Gkinis, Alexis Roche, Tobias Kober, Bénédicte Maréchal, Nadia Ortiz, Karl-Olof Lövblad, François Lazeyras, Maria Isabel Vargas
AIM: To evaluate brain atrophy in anorexic patients by automated cerebral segmentation with the magnetization-prepared 2 rapid acquisition gradient echo (MP2RAGE) MRI sequence. MATERIAL AND METHODS: Twenty patients (female; mean age, 27.9 years), presenting consecutively for brain MRI between August 2014-December 2016 with clinical suspicion of anorexia nervosa and BMI<18.5 kg/m(2) were included. Controls were ten healthy females (mean age, 26.5 years). Automated brain morphometry was performed based on MP2RAGE...
June 21, 2017: European Radiology
https://www.readbyqxmd.com/read/28636668/microbiota-in-anorexia-nervosa-the-triangle-between-bacterial-species-metabolites-and-psychological-tests
#7
Francesca Borgo, Alessandra Riva, Alberto Benetti, Maria Cristina Casiraghi, Sara Bertelli, Stefania Garbossa, Simona Anselmetti, Silvio Scarone, Antonio E Pontiroli, Giulia Morace, Elisa Borghi
Anorexia nervosa (AN) is a psychiatric disease with devastating physical consequences, with a pathophysiological mechanism still to be elucidated. Metagenomic studies on anorexia nervosa have revealed profound gut microbiome perturbations as a possible environmental factor involved in the disease. In this study we performed a comprehensive analysis integrating data on gut microbiota with clinical, anthropometric and psychological traits to gain new insight in the pathophysiology of AN. Fifteen AN women were compared with fifteen age-, sex- and ethnicity-matched healthy controls...
2017: PloS One
https://www.readbyqxmd.com/read/28635077/self-disgust-within-eating-disordered-groups-associations-with-anxiety-disgust-sensitivity-and-sensory-processing
#8
Katie Bell, Helen Coulthard, Diane Wildbur
This study aimed to assess the relationship between self-disgust and sensory processing within eating psychopathology. Five hundred and ninety-one women with a self-reported diagnosis of anorexia nervosa, bulimia nervosa or who had no previous history of an eating disorder completed a battery of online questionnaires measuring disgust, emotion and sensory variables. Those with an eating disorder reported significantly higher rates of self-disgust than those with no history of disordered eating. In groups of women with self-reported bulimia, self-disgust was associated with sensation avoidance and sensation seeking...
June 20, 2017: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://www.readbyqxmd.com/read/28630708/what-happens-after-treatment-a-systematic-review-of-relapse-remission-and-recovery-in-anorexia-nervosa
#9
REVIEW
Sahib S Khalsa, Larissa C Portnoff, Danyale McCurdy-McKinnon, Jamie D Feusner
BACKGROUND: Relapse after treatment for anorexia nervosa (AN) is a significant clinical problem. Given the level of chronicity, morbidity, and mortality experienced by this population, it is imperative to understand the driving forces behind apparently high relapse rates. However, there is a lack of consensus in the field on an operational definition of relapse, which hinders precise and reliable estimates of the severity of this issue. The primary goal of this paper was to review prior studies of AN addressing definitions of relapse, as well as relapse rates...
2017: Journal of Eating Disorders
https://www.readbyqxmd.com/read/28630421/a-genome-wide-association-study-of-anorexia-nervosa-suggests-a-risk-locus-implicated-in-dysregulated-leptin-signaling
#10
Dong Li, Xiao Chang, John J Connolly, Lifeng Tian, Yichuan Liu, Elizabeth J Bhoj, Nora Robinson, Debra Abrams, Yun R Li, Jonathan P Bradfield, Cecilia E Kim, Jin Li, Fengxiang Wang, James Snyder, Maria Lemma, Cuiping Hou, Zhi Wei, Yiran Guo, Haijun Qiu, Frank D Mentch, Kelly A Thomas, Rosetta M Chiavacci, Roger Cone, Bingshan Li, Patrick A Sleiman, Hakon Hakonarson
We conducted a genome-wide association study (GWAS) of anorexia nervosa (AN) using a stringently defined phenotype. Analysis of phenotypic variability led to the identification of a specific genetic risk factor that approached genome-wide significance (rs929626 in EBF1 (Early B-Cell Factor 1); P = 2.04 × 10(-7); OR = 0.7; 95% confidence interval (CI) = 0.61-0.8) with independent replication (P = 0.04), suggesting a variant-mediated dysregulation of leptin signaling may play a role in AN...
June 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28624376/orthorexia-nervosa-and-eating-disorder-symptoms-in-registered-dietitian-nutritionists-in-the-united-states
#11
Kaylee Tremelling, Lona Sandon, Gloria L Vega, Carrie J McAdams
BACKGROUND: Registered dietitian nutritionists are trained to identify optimal food choices for clients based on medical state and lifestyle. Orthorexia nervosa (ON) is a proposed disorder related to obsessions about eating healthfully. Eating disorders (EDs) are serious mental illnesses with symptoms related to eating, body image, and self-esteem. Both ON and EDs are more common among RDNs than the general population. OBJECTIVE: This study examined the prevalence of ON and EDs in RDNs in the United States and, among this sample, assessed whether the presence of ON symptoms related to symptoms of EDs, including weight, shape, eating, and restraint...
June 14, 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28623853/the-validity-of-dsm-5-severity-specifiers-for-anorexia-nervosa-bulimia-nervosa-and-binge-eating-disorder
#12
Kathryn E Smith, Jo M Ellison, Ross D Crosby, Scott G Engel, James E Mitchell, Scott J Crow, Carol B Peterson, Daniel Le Grange, Stephen A Wonderlich
OBJECTIVE: The DSM-5 includes severity specifiers (i.e., mild, moderate, severe, extreme) for anorexia nervosa (AN), bulimia nervosa (BN), and binge-eating disorder (BED), which are determined by weight status (AN) and frequencies of binge-eating episodes (BED) or inappropriate compensatory behaviors (BN). Given limited data regarding the validity of eating disorder (ED) severity specifiers, this study examined the concurrent and predictive validity of severity specifiers in AN, BN, and BED...
June 17, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28618917/reduced-cardiovascular-activation-following-chronic-stress-in-caregivers-of-people-with-anorexia-nervosa
#13
Ángel Romero-Martínez, Luis Moya-Albiol
Caring for offspring diagnosed with eating disorders (EDs) puts caregivers under high levels of chronic stress, which have negative consequences for their health. Unfortunately, caregivers have received little attention from mental health professionals. Chronic stress experienced by informal caregivers has been associated with the alteration of body homeostasis, and therefore, the functioning of various physiological systems. This could be the basis of health problems in informal caregivers of people with EDs...
June 15, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/28615982/family-based-treatment-of-eating-disorders-in-adolescents-current-insights
#14
REVIEW
Renee D Rienecke
Eating disorders are serious illnesses associated with significant morbidity and mortality. Family-based treatment (FBT) has emerged as an effective intervention for adolescents with anorexia nervosa, and preliminary evidence suggests that it may be efficacious in the treatment of adolescents with bulimia nervosa. Multifamily therapy for anorexia nervosa provides a more intensive experience for families needing additional support. This review outlines the three phases of treatment, key tenets of family-based treatment, and empirical support for FBT...
2017: Adolescent Health, Medicine and Therapeutics
https://www.readbyqxmd.com/read/28606779/2-arachidonoylglycerol-as-a-possible-treatment-for-anorexia-nervosa-in-animal-model-in-mice
#15
Y Avraham, I Paturski, I Magen, L Vorobiev, E M Berry
We have investigated the effects of 0.001mg/kg 2-arachidonoylglycerol (2-AG) administered in combination with compounds present in the body alongside 2-AG like 2-palmitoylglycerol and 2-linoleylglycerol (also termed "entourage"), on cognitive function,food intake, and neurotransmitter levels in the hippocampus and hypothalamus of mice under diet restriction. Young female Sabra mice were treated with vehicle, 2-AG, 2-AG + entourage, 2-AG + entourage + 5-(4-Chlorophenyl)-1-(2,4-dichloro-phenyl)- 4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide (SR141716A, a CB1 antagonist) and SR141716A...
June 9, 2017: Brain Research
https://www.readbyqxmd.com/read/28605663/patients-with-bulimia-nervosa-do-not-show-typical-neurodevelopment-of-cognitive-control-under-emotional-influences
#16
Michael F W Dreyfuss, Melissa L Riegel, Gloria A Pedersen, Alexandra O Cohen, Melanie R Silverman, Jonathan P Dyke, Laurel E S Mayer, B Timothy Walsh, B J Casey, Allegra I Broft
Bulimia nervosa (BN) emerges in the late teen years and is characterized by binge eating and related compensatory behaviors. These behaviors often co-occur with periods of negative affect suggesting an association between emotions and control over eating behavior. In the current study, we examined how cognitive control and neural processes change under emotional states of arousal in 46 participants with (n=19) and without (n=27) BN from the ages of 18-33 years. Participants performed a go/nogo task consisting of brief negative, positive and neutral emotional cues and sustained negative, positive and neutral emotional states of arousal during functional magnetic resonance imaging (fMRI)...
May 10, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28604943/adipokine-profile-in-patients-with-anorexia-nervosa
#17
Agnieszka Baranowska-Bik, Bogusława Baranowska, Lidia Martyńska, Anna Litwiniuk, Małgorzata Kalisz, Jan Kochanowski, Wojciech Bik
INTRODUCTION: Anorexia nervosa (AN) is an eating disorder characterised with extremely low weight. Adipokines are adipose tissue-derived substances that show a wide spectrum of biological activities. We aimed to assess selected adipokine levels in women with AN before and after nutritional intervention. We also sought to examine whether BMI is the only confounding factor influencing adipokine assessment in AN. MATERIAL AND METHODS: Sixty-five women participated in the study: 20 individuals with AN before any treatment, 18 AN patients after nutritional intervention lasting for at least six months, and 27 women as controls...
June 12, 2017: Endokrynologia Polska
https://www.readbyqxmd.com/read/28601992/prevalence-of-idiopathic-scoliosis-in-anorexia-nervosa-patients-results-from-a-cross-sectional-study
#18
Fabio Zaina, Francesca Pesenti, Luca Persani, Paolo Capodaglio, Stefano Negrini, Nicoletta Polli
PURPOSE: A long debate exists about the connection between anorexia nervosa (AN) and scoliosis due to conflicting evidence. No study so far has evaluated the prevalence of scoliosis in patients with AN. The aim of the study is to evaluate the prevalence of idiopathic scoliosis in patients with AN. METHODS: Design: cross-sectional study. STUDY GROUP: convenience sample of all patients matching the inclusion criteria. CONTROL GROUP: female participants coming from an epidemiological screening for scoliosis...
June 10, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28593722/macronutrient-intake-associated-with-weight-gain-in-adolescent-girls-with-anorexia-nervosa
#19
Charumathi Baskaran, Traci L Carson, Karen J Campoverde Reyes, Kendra R Becker, Meghan J Slattery, Shreya Tulsiani, Kamryn T Eddy, Ellen J Anderson, Jane L Hubbard, Madhusmita Misra, Anne Klibanski
OBJECTIVE: Adolescents and women with anorexia nervosa (AN) are known to severely restrict total calorie and fat intake. However, data are limited regarding specific macronutrient intake associated with weight gain in AN. OBJECTIVE: To prospectively investigate dietary macronutrient composition associated with weight gain in adolescent girls with AN. METHOD: A prospective naturalistic study of 90 girls 12-18 years old; 45 with AN and 45 healthy normal-weight-controls over a 6-12-month period...
June 7, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28593655/vitamin-d-levels-strongly-influence-bone-mineral-density-and-bone-turnover-markers-during-weight-gain-in-female-patients-with-anorexia-nervosa
#20
Alessandro Giollo, Luca Idolazzi, Cristian Caimmi, Angelo Fassio, Francesco Bertoldo, Riccardo Dalle Grave, Marwan El Ghoch, Simona Calugi, Paola Vittoria Bazzani, Ombretta Viapiana, Maurizio Rossini, Davide Gatti
OBJECTIVE: The aim of the study was to investigate a potential role for vitamin D status on bone mineral density (BMD) during weight gain in patients with anorexia nervosa (AN). METHOD: Spine and hip BMD assessed by dual-energy X-ray absorptiometry (DXA), serum vitamin D (25-OH-D), N-propeptide of type I collagen (P1NP), C-terminal telopeptide of type I collagen (CTX), and intact parathyroid hormone (PTH) were measured before and after a 20-week intensive weight-restoration program in ninety-one female patients with AN and secondary amenorrhoea...
June 7, 2017: International Journal of Eating Disorders
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