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https://www.readbyqxmd.com/read/28651342/emissions-of-volatile-odorous-metabolites-by-clostridium-perfringens-in-vitro-study-using-two-broth-cultures
#1
Nishchal K Sharma, Chuck Keerqin, Shu-Biao Wu, Mingan Choct, Robert A Swick
An in vitro study was carried out to investigate the volatile odorous metabolites produced by necrotic enteritis inducing Clostridium perfringens (Cp) type A field strain (EHE-NE18) cultured in two broth media (thioglycollate broth, brain heart infusion broth) at three levels (0, 103 cfu/mL, 106 cfu/mL) using 2 × 3 factorial arrangement of treatments, with each replicated three times. The culture media with and without Cp was freshly prepared on the day of measurement and the culture headspace concentration of odorants was measured using selected ion-flow tube mass spectrometry (SIFT-MS)...
June 23, 2017: Poultry Science
https://www.readbyqxmd.com/read/28651327/alpha-klotho-and-fibroblast-growth-factor-23-among-alcoholics
#2
Geraldine Quintero-Platt, Emilio González-Reimers, Melchor Rodríguez-Gaspar, Candelaria Martín-González, Onán Pérez-Hernández, Lucía Romero-Acevedo, Elisa Espelosín-Ortega, María José de la Vega-Prieto, Francisco Santolaria-Fernández
Aims: Alcoholism may be a cardiovascular risk factor. Osteocyte derived molecules such as fibroblast growth factor 23 (FGF-23) and soluble α Klotho have recently been associated with cardiovascular disease, but their role in alcoholics is unknown. We here analyze the behavior of FGF23 and α Klotho in alcoholics. Methods: Ninety-seven alcoholic patients were assessed for liver function, presence of hypertension, diabetes, atrial fibrillation, left ventricular hypertrophy (LVH), vascular calcifications (assessed by chest X-ray) and nutritional status (lean and fat mass measured by densitometry)...
June 23, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28651189/sex-specific-effects-of-difenoconazole-on-the-growth-hormone-endocrine-axis-in-adult-zebrafish-danio-rerio
#3
Miaomiao Teng, Suzhen Qi, Wentao Zhu, Yao Wang, Dezhen Wang, Yang Yang, Hui Li, Chenglong Li, Kai Dong, Chengju Wang
Difenoconazole, as one of the most widely used triazole fungicides, is applied to protect crops, fruits, and vegetables. It has been reported that difenoconazole can enter the environment and impair aquatic organisms, but whether difenoconazole can disrupt the growth hormone (GH) balance in adult zebrafish (Danio rerio) is still unclear. In this study, adult female and male zebrafish were exposed to difenoconazole (0, 5, 50, and 500µg/L) for seven days. The results revealed that the bioaccumulation of difenoconazole and its primary metabolite difenoconazole alcohol in females were both larger than that in males...
June 23, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28651146/the-effects-of-drinking-and-driving-laws-on-car-crashes-injuries-and-deaths-evidence-from-chile
#4
Sebastián Otero, Tomás Rau
This paper analyzes the effects of lowering the legal blood alcohol content limit for drivers from 0.05 to 0.03 grams of alcohol per deciliter of blood (g/dL) and increasing license suspension periods for offenders. We take advantage of a rich data set of administrative records that allow us to identify direct measures of accidents involving alcohol including fatalities and injuries. Results show a significant decrease of 32% in alcohol-related car accidents right after the law was approved but the effects moderate over time (15% after three years)...
June 23, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28651142/fast-pyrolysis-of-durian-durio-zibethinus-l-shell-in-a-drop-type-fixed-bed-reactor-pyrolysis-behavior-and-product-analyses
#5
Y L Tan, A Z Abdullah, B H Hameed
Durian shell (DS) was pyrolyzed in a drop-type fixed-bed reactor to study the physicochemical properties of the products. The experiment was carried out with different particle sizes (up to 5mm) and reaction temperatures (250-650°C). The highest bio-oil yield was obtained at 650°C (57.45wt%) with DS size of 1-2mm. The elemental composition and higher heating value of the feedstock, bio-oil (650°C), and bio-char (650°C) were determined and compared. The compositions of product gases were determined via gas chromatography with thermal conductivity detector...
June 23, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28651109/separation-of-furostanol-saponins-by-supercritical-fluid-chromatography
#6
Jie Yang, Lingling Zhu, Yang Zhao, Yongwei Xu, Qinglong Sun, Shuchen Liu, Chao Liu, Baiping Ma
Supercritical fluid chromatography (SFC) has good separation efficiency and is suitable for separating weakly polar compounds. Furostanol saponins, as an important kind of steroidal saponins, generally have two sugar chains, which are polar and hydrophilic. The hydroxyl group at the C-22 position of furostanol saponins is active and easily reacts with lower alcohols under appropriate conditions. The separation of hydrophilic furostanol saponins was tested by SFC in this study. The effects of chromatographic conditions on the separation of the mixed furostanol saponins and their hydroxyl derivatives at the C-22 position were studied...
June 19, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28651084/treatment-of-food-waste-recycling-wastewater-using-anaerobic-ceramic-membrane-bioreactor-for-biogas-production-in-mainstream-treatment-process-of-domestic-wastewater
#7
Yeongmi Jeong, Slawomir W Hermanowicz, Chanhyuk Park
A bench-scale anaerobic membrane bioreactor (AnMBR) equipped with submerged flat-sheet ceramic membranes was operated at mesophilic conditions (30-35 °C) treating domestic wastewater (DWW) supplemented with food wasterecycling wastewater (FRW) to increase the organic loading rate (OLR) for better biogas production. Coupling ceramic membrane filtration with AnMBR treatment provides an alternative strategy for high organic wastewater treatment at short hydraulic retention times (HRTs) with the potential benefits of membrane fouling because they have a high hydrophilicity and more robust at extreme conditions...
June 19, 2017: Water Research
https://www.readbyqxmd.com/read/28650726/maternal-health-related-behaviours-during-pregnancy-a-critical-public-health-issue
#8
Aleksandra Górniaczyk, Barbara Czech-Szczapa, Maciej Sobkowski, Karolina Chmaj-Wierzchowska
AIM: The aim of the study was to investigate the health-related behaviours of pregnant women. Maternal health-related habits, use of psychoactive medicines, diet, prevention of neural tube defects, oral cavity hygiene, chronic diseases and physical activity were analysed in a group of pregnant women attending antenatal classes. METHODS: Hundred pregnant women recruited from various antenatal classes in Poznań, Poland, were investigated using a questionnaire based on the Pregnancy Risk Assessment Monitoring System...
June 26, 2017: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/28650618/solution-and-solid-state-correlations-of-antimalarial-drug-actions-nmr-and-crystallographic-studies-of-drug-interactions-with-a-heme-model
#9
Erin L Dodd, Dagobert Tazoo, D Scott Bohle
Solution NMR has been used in tandem with a diamagnetic non-iron heme model compound as a simple and effective tool to rapidly probe the structures of the bound complexes formed between the metalloporphyrin and antimalarial drugs from the 4-aminoquinoline, 4-methylenehydroxylquinoline, and 8-aminoquinoline subfamilies. The ability of gallium(III) protoporphyrin IX to mimic heme chemistry is exploited. The 4-aminoquinolines quinacrine and amodiaquine and two novel 3-halo chloroquine analogues are found to bind to the metalloporphyrin through hydrogen-bonding and stacking interactions, while halofantrine and the 4-methylenehydroxylquinolines, quinine and mefloquine bind through the alcohol group of the drug...
June 26, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28650591/the-silver-lining-towards-the-responsible-and-limited-usage-of-silver
#10
REVIEW
Kshipra Naik, Meenal Kowshik
Silver has attracted a lot of attention as a powerful, broad spectrum and natural antimicrobial agent since the ancient times because of its non-toxic nature to the human body at low concentrations. It has been used in treatment of various infections and ulcers, storage of water, and prevention of bacterial growth on the surfaces and within materials. However there are numerous medical and health benefits of colloidal or nano silver apart from its microbicidal ability which as yet have not been fully embraced by the medical community...
June 26, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28650518/a-simple-in-silico-strategy-identifies-candidate-biomarkers-for-the-diagnosis-of-liver-fibrosis-in-morbidly-obese-subjects
#11
Pablo J Giraudi, Sabrina E Gambaro, Sofia Ornelas Arroyo, Carla M Chackelevicius, Michela Giuricin, Marta Silvestri, Daniele Macor, Lory S Crocé, Deborah Bonazza, Giorgio Soardo, Nicolò de Manzini, Fabrizio Zanconati, Claudio Tiribelli, Silvia Palmisano, Natalia Rosso
BACKGROUND AND AIMS: Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disorder, tightly associated with obesity. The histological spectrum of the disease ranges from simple steatosis to steatohepatitis, with different stages of fibrosis, and fibrosis stage is the most significant predictor of mortality in NAFLD. Liver biopsy continues to be the gold standard for its diagnosis and reliable non-invasive diagnostic tools are unavailable. We investigated the accuracy of candidate proteins, identified by an in silico approach, as biomarkers for diagnosis of fibrosis...
June 26, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/28650491/tunable-and-selective-hydrogenation-of-furfural-to-furfuryl-alcohol-and-cyclopentanone-over-pt-supported-on-biomass-derived-porous-heteroatom-doped-carbon
#12
Xiuyun Liu, Bo Zhang, Benhua Fei, Xiufang Chen, Junyi Zhang, Xindong Mu
The search for and exploitation of efficient catalytic systems for selective conversion of furfural into various high value-added chemicals remains a huge challenge for green synthesis in the chemical industry. Here, novel Pt nanoparticles supported on bamboo shoot-derived porous heteroatom doped carbon materials were designed as highly active catalysts for controlled hydrogenation of furfural in aqueous media. The porous heteroatom doped carbon supported Pt catalysts were endowed with a large surface area with a hierarchical porous structure, a high content of nitrogen and oxygen functionalities, a high dispersion of the Pt nanoparticles, good water dispersibility and reaction stability...
June 26, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/28650391/proteins-differentially-expressed-in-the-pancreas-of-hepatic-alcohol-dehydrogenase-deficient-deer-mice-fed-ethanol-for-3-months
#13
Kamlesh K Bhopale, Samir M Amer, Lata Kaphalia, Kizhake V Soman, John E Wiktorowicz, Ghulam A Shakeel Ansari, Bhupendra S Kaphalia
OBJECTIVES: The aim of this study was to identify differentially expressed proteins in the pancreatic tissue of hepatic alcohol dehydrogenase-deficient deer mice fed ethanol to understand metabolic basis and mechanism of alcoholic chronic pancreatitis. METHODS: Mice were fed liquid diet containing 3.5 g% ethanol daily for 3 months, and differentially expressed pancreatic proteins were identified by protein separation using 2-dimensional gel electrophoresis and identification by mass spectrometry...
June 22, 2017: Pancreas
https://www.readbyqxmd.com/read/28650247/burden-of-alcohol-abuse-or-dependence-among-long-term-opioid-users-with-chronic-noncancer-pain
#14
Pamela B Landsman-Blumberg, Nathaniel Katz, Kavita Gajria, Anna D Coutinho, Paul P Yeung, Richard White
BACKGROUND: Substance abuse disorders among chronic noncancer pain (CNCP) patients add to the clinical challenges and economic burden of caring for such patients. Despite potential risks, some CNCP patients with a history of alcohol abuse or dependence (AAD) and pain that is refractory to nonopioid treatment options may still need opioids for pain management. However, there is a lack of data on adverse outcomes in long-term opioid users with CNCP and a history of substance abuse or AAD disorders...
July 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28650230/get-real-evaluation-of-a-community-level-hiv-prevention-intervention-for-young-msm-who-engage-in-episodic-substance-use
#15
Jennifer Lauby, Lin Zhu, Mary Milnamow, Heather Batson, Lisa Bond, William Curran-Groome, Lee Carson
Young men who have sex with men (YMSM) have high rates of recreational drug use and binge drinking that are related to increases in unprotected sex and HIV risk. We describe the development of a community-level intervention focused on MSM ages 15 to 29 who identify as Black or White and who reported episodic use of alcohol and/or drugs. Intervention content included culturally-relevant role model stories and peer outreach. Outcome measures, including number of partners and a risk score indicating risk for HIV from protected or unprotected insertive or receptive anal sex, were examined over 36 months in a sample of YMSM in Philadelphia, the intervention site, and Baltimore, the comparison site...
June 2017: AIDS Education and Prevention: Official Publication of the International Society for AIDS Education
https://www.readbyqxmd.com/read/28650226/correlates-of-hiv-risks-among-women-on-probation-and-parole
#16
Malitta Engstrom, Katherine M Winham, Seana Golder, George Higgins, Tanya Renn, T K Logan
This article examines HIV risks among a sample of 406 women on probation and parole with lifetime histories of victimization who were recruited from an urban community in the southern U.S. Guided by the Comprehensive Health Seeking and Coping Paradigm, we analyze the significance of sociodemographic characteristics, substance use, posttraumatic stress disorder, and social support in relationship to three sexual risks and one drug use risk using multivariable regression. Findings indicate that substance use is a significant correlate of nearly all HIV risks examined, including lifetime sexual partners and sexual partners during the past 12 months...
June 2017: AIDS Education and Prevention: Official Publication of the International Society for AIDS Education
https://www.readbyqxmd.com/read/28650223/alcohol-related-posts-from-young-people-on-social-networking-sites-content-and-motivations
#17
Hanneke Hendriks, Winifred A Gebhardt, Bas van den Putte
Many young people place alcohol-related posts on social networking sites (SNS) which can result in undesirable effects. Although several recent studies have investigated the occurrence of alcohol-related SNS use, it is neither clear (a) what type of alcohol posts are placed on SNS, (b) the motivations to place alcohol posts, nor (c) which young people are most likely to place alcohol posts. This study addressed these three goals. A large cross-sectional study among young participants (12-30 years; N = 561) assessed the posting of different types of alcohol posts, the motivations to (not) post these posts, and potential differences in posting between subgroups (i...
June 26, 2017: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/28650221/a-cross-cultural-study-of-risky-online-self-presentation
#18
Claire M White, Clara A Cutello, Michaela Gummerum, Yaniv Hanoch
The use of social media is pervasive among young adults. However, not all posted content is beneficial to their self-presentation, but can have negative and damaging consequences. This study investigated how individual differences in self-monitoring and impulsiveness influence risky online self-presentation in British and Italian samples. British participants (n = 88) were more likely to post comments and images related to their alcohol and drug use, whereas Italian (n = 90) participants posted more offensive content and personal information...
June 26, 2017: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/28650205/investigation-of-the-hepatoprotective-effect-of-prunus-mume-sieb-et-zucc-extract-in-a-mouse-model-of-alcoholic-liver-injury-through-high-resolution-metabolomics
#19
Adnan Khan, Jeong Hoon Pan, Seongha Cho, Sojung Lee, Young Jun Kim, Youngja H Park
This study aimed to identify the changes in the metabolomics profile of liver damage caused by alcohol consumption and verify beneficial effect of Prunus mume Sieb. et Zucc extract (PME) in protection of alcohol-induced injury by attenuating the level of identified metabolites. Mice were treated with PME and saline or untreated once daily for 5 days, followed by alcohol injection. The plasma samples were analyzed using liquid chromatography-mass spectrometry-based high-resolution metabolomics followed by a multivariate statistical analysis using MetaboAnalyst 3...
June 26, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28649963/the-effect-of-growth-medium-on-i-escherichia-coli-i-pathway-mirrored-into-gc-ms-profiles
#20
Ileana Andreea Ratiu, Tomasz Ligor, Victor Bocos-Bintintan, Hossam Al-Suod, Tomasz Kowalkowski, Katarzyna Rafińska, Boguslaw Buszewski
Escherichia coli (E. coli) is a gram-negative coliform bacterium that is commonly found in the lower intestine of warm-blooded organisms. Most of the strains are harmless, but some serotypes are pathogenic, meaning they can cause illness, either diarrhea or illness outside of the intestinal tract. The aim of this work was to assess which components are generated in case of E. coli target analysis needed. In this purpose our study intends to emphasize the importance of the cultivability and to prove the crucial role of growth media used in bacteria growing...
June 26, 2017: Journal of Breath Research
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