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Hemorrhoidal disease

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https://www.readbyqxmd.com/read/29682371/colonic-mucosal-ulceration-and-gastrointestinal-bleeding-associated-with-sevelamer-crystal-deposition-in-a-patient-with-end-stage-renal-disease
#1
Sudheer Nambiar, Unnikrishnan Kunjan Pillai, Joe Devasahayam, Tony Oliver, Asha Karippot
End stage renal disease (ESRD) population account for 1.9 per patient year of hospital admissions annually. ESRD population are at increased risk of bleeding secondary to use of anticoagulation during hemodialysis and uremia induced platelet dysfunction. Gastrointestinal bleeding accounts for 3-7% of all deaths in ESRD population. Lower gastrointestinal bleeding refers to blood loss from a site in the gastrointestinal tract distal to the ligament of Treitz. It is usually suspected when a patient complains of hematochezia...
2018: Case Reports in Nephrology
https://www.readbyqxmd.com/read/29680897/towards-a-core-outcome-set-for-hemorrhoidal-disease-a-systematic-review-of-outcomes-reported-in-literature
#2
REVIEW
R R van Tol, E van Zwietering, J Kleijnen, J Melenhorst, L P S Stassen, C D Dirksen, S O Breukink
PURPOSE: Previously published literature regarding treatment of hemorrhoidal disease (HD) revealed a lack of uniform defined outcomes. These differences between outcomes among studies limit transparency and lead to incomparability of results. The aim of this study was to systematically list the types of outcomes used in HD studies. This list will be used to develop a core outcome set. METHODS: We searched Medline (Pubmed), Embase (OVID), and Cochrane for interventional studies for adult patients with HD...
April 22, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29652112/mucopexy-recto-anal-lifting-mu-ral-a-standardized-minimally-invasive-method-of-managing-symptomatic-hemorrhoids-with-an-innovative-suturing-technique-and-the-hemorpex-system%C3%A2
#3
Claudio Pagano, Contardo Vergani, Carlo Invernizzi, Massimo Bussone, Guido Benegiamo, Marco Venturi
BACKGROUND: Conservative surgery of hemorrhoidal disease is less painful than traditional hemorrhoidectomy, and mucopexy has less risk of serious postoperative complications than stapled hemorrhoidopexy. The aim of this study was to evaluate the safety and effectiveness of a standardized, modified hemorrhoidopexy, named Mucopexy-Recto Anal Lifting (MuRAL),with the HemorPex System (HPS) in patients with symptomatic III and IV degree hemorrhoids. MATERIALS AND METHODS: Patients were enrolled from May 2013 to Dec 2015 and operated on with the MuRAL technique, based on arterial ligation and mucopexy at 6 locations, using a standardized clockwise/anti-clockwise rotation sequence of the HPS anoscope...
April 12, 2018: Minerva Chirurgica
https://www.readbyqxmd.com/read/29601902/rethinking-what-we-know-about-hemorrhoids
#4
REVIEW
Robert S Sandler, Anne F Peery
Although hemorrhoids are responsible for considerable economic cost and personal suffering, they have received surprisingly little research attention. In the United States, hemorrhoids are the third most common outpatient gastrointestinal diagnosis with nearly 4 million office and emergency department visits annually. The etiology of hemorrhoids is speculative. A low-fiber diet and constipation have historically been thought to increase the risk for hemorrhoids, but not proven. Symptoms commonly attributed to hemorrhoids include bleeding, pain, pruritus, fecal seepage, prolapse and mucus discharge...
March 27, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29577224/-relationship-between-the-expression-of-ddx39-protein-and-prognosis-of-colorectal-cancer
#5
Jun Ma, Wenjun Chang, Wei Zhang
OBJECTIVE: To investigate the relationship between the expression of DDX39 protein and prognosis in colorectal cancer. METHODS: Clinical data and paraffin specimens of postoperative tumor tissue from 824 patients with primary colorectal cancer who received first surgical treatment at the Department of Colorectal Surgery of Changhai Hospital of Navy Military Medical University from January 2010 to December 2011 were collected. Paraffin samples of paracancerous tissues of 38 patients were served as controls...
March 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29577215/-current-status-in-surgical-treatment-of-constipation
#6
Jiexuan Wang, Wei Cai
Chronic constipation is a polysymptomatic heterogeneous disorder with the incidence rising in many countries, and becomes a common disease affecting the quality of life and financial burden. In China surgical guideline, the primary constipation is divided into 3 types: slow transit constipation, outlet obstructive constipation, mixed constipation. The Rome IIII( criteria is usually referred to diagnosis, considering with clinical features and patient complaints. Through detail interrogation, physical examination and various detections, the secondary causes should be excluded, and etiological treatment is worth to try...
March 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29546558/a-national-evaluation-of-the-management-practices-of-hemorrhoidal-disease-in-the-netherlands
#7
Robin R van Tol, Marieke P A Bruijnen, Jarno Melenhorst, Sander M J van Kuijk, Laurents P S Stassen, Stéphanie O Breukink
PURPOSE: In this study, we describe current practices in the management of hemorrhoidal disease in the Netherlands. METHODS: A validated online survey was performed among Dutch surgeons and residents treating hemorrhoidal disease. Contact details were retrieved from the Dutch Association for Surgery resulting in 619 contacts. Only doctors who were treating hemorrhoidal disease regularly were asked to complete the questionnaire. The following items were assessed: initial treatment, recurrence, complications, and follow-up...
March 15, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29526242/traditional-and-modern-aspects-of-hemorrhoid-treatment-in-iran-a-review
#8
REVIEW
Sahar Dehdari, Homa Hajimehdipoor, Somayeh Esmaeili, Rasool Choopani, Seyed Alireza Mortazavi
Hemorrhoidal disease is a prevalent anorectal condition which is generally not managed well with current pharmacologic interventions. However, in Iranian traditional medicine (ITM) there are numerous plants with hemorrhoid-healing properties. The present research assembled plants with hemorrhoid-healing properties in ITM; their related pharmacological effects, phytochemical constituents and mechanisms of action in the modern medicine were also gathered. For this purpose, leading ITM textbooks were searched for plants with hemorrhoid-healing effects...
March 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29504471/transanal-hemorrhoidal-dearterialization-versus-stapled-hemorrhoidopexy-long-term-follow-up-of-a-prospective-randomized-study
#9
Gabriella Giarratano, Edoardo Toscana, Claudio Toscana, Giuseppe Petrella, Mostafa Shalaby, Pierpaolo Sileri
AIM: This study aims to compare the early and late outcomes of transanal hemorrhoidal dearterialization (THD) versus stapled hemorrhoidopexy (SH) for the treatment of hemorrhoidal disease. METHODS: From January 2013 to December 2014, 100 patients-50 patients on each arm-were randomly allocated to THD or SH groups. The inclusion criteria were grade III and IV hemorrhoids diagnosed by clinical examination and proctoscopy. The primary outcome was to compare the recurrence rate with a minimum follow-up of 2 years, and the secondary outcome was to compare complications rate, time to return to work postsurgery, procedure length, and patient's satisfaction between the 2 techniques...
March 1, 2018: Surgical Innovation
https://www.readbyqxmd.com/read/29499172/management-of-common-benign-anorectal-disease-what-all-physicians-need-to-know
#10
REVIEW
David Parés, Herand Abcarian
Benign anorectal conditions produce anal pain, rectal bleeding, or discharge from the perianal region, which are highly prevalent symptoms in the general population. Hemorrhoidal disease, anal fissure, perianal abscess, proctalgia syndromes and pruritus anii are the most common clinical disorders. Well-trained physicians irrespective of their specialty can treat most of these disorders and refer them to a specialist in proctology only when necessary. The aim of this review is to provide a practical guide to the management of benign anorectal disorders in terms of their initial management and the criteria for specialist referral...
February 27, 2018: American Journal of Medicine
https://www.readbyqxmd.com/read/29492831/correction-to-transanal-hemorrhoidal-dearterialization-thd-for-hemorrhoidal-disease-a-single-center-study-on-1000-consecutive-cases-and-a-review-of-the-literature
#11
Carlo Ratto, Paola Campennì, Francesco Papeo, Lorenza Donisi, Francesco Litta, Angelo Parello
The article "Transanal hemorrhoidal dearterialization (THD) for hemorrhoidal disease: a single-center study on 1000 consecutive cases and a review of the literature" written by C. Ratto et al. was originally published Online First without open access.
February 28, 2018: Techniques in Coloproctology
https://www.readbyqxmd.com/read/29432419/an-efficient-bayesian-meta-analysis-approach-for-studying-cross-phenotype-genetic-associations
#12
Arunabha Majumdar, Tanushree Haldar, Sourabh Bhattacharya, John S Witte
Simultaneous analysis of genetic associations with multiple phenotypes may reveal shared genetic susceptibility across traits (pleiotropy). For a locus exhibiting overall pleiotropy, it is important to identify which specific traits underlie this association. We propose a Bayesian meta-analysis approach (termed CPBayes) that uses summary-level data across multiple phenotypes to simultaneously measure the evidence of aggregate-level pleiotropic association and estimate an optimal subset of traits associated with the risk locus...
February 2018: PLoS Genetics
https://www.readbyqxmd.com/read/29431977/hemorrhoids-diagnosis-and-treatment-options
#13
Timothy Mott, Kelly Latimer, Chad Edwards
Many Americans between 45 and 65 years of age experience hemorrhoids. Hemorrhoidal size, thrombosis, and location (i.e., proximal or distal to the dentate line) determine the extent of pain or discomfort. The history and physical examination must assess for risk factors and clinical signs indicating more concerning disease processes. Internal hemorrhoids are traditionally graded from I to IV based on the extent of prolapse. Other factors such as degree of discomfort, bleeding, comorbidities, and patient preference should help determine the order in which treatments are pursued...
February 1, 2018: American Family Physician
https://www.readbyqxmd.com/read/29228790/an-evidence-based-study-on-medicinal-plants-for-hemorrhoids-in-medieval-persia
#14
Mohammad Hashem Hashempur, Fatemeh Khademi, Maryam Rahmanifard, Mohammad M Zarshenas
Hemorrhoids is one of the most common gastrointestinal diseases. There are several therapeutic options associated with some complications. Therefore, researchers look for traditional medicines as a potential resource for introduction of new natural drugs. The current study reports an evidence-based review of herbal remedies for hemorrhoids in traditional Persian medicine. A comprehensive survey about hemorrhoids on the most important manuscripts of traditional Persian medicine was done. Then, scientific data banks were searched for possible related properties of each herb in the conventional medicine...
October 2017: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/29186745/-laserhemorrhoidoplasty-with-1470-nm-diode-laser-in-the-treatment-of-second-to-fourth-degree-hemorrhoidal-disease-a-cohort-study-with-497-patients
#15
Guido Weyand, Claudia Susanne Theis, Aboubacar Nzambi Fofana, Felix Rüdiger, Thomas Gehrke
Background Laser haemorrhoidoplasty (LHP) with the 1470 nm diode laser in minimally invasive surgery for advanced haemorrhoid disease has been studied with respect to clinical variables, such as pain and complications, and intraoperative characteristics such as mucopexia, number of treated knots and energy consumed per patient. The study also included patient satisfaction, symptom relevance and cost effectiveness. Patients and Methods Between November 2010 and November 2016, 497 patients (age 55 ± 14 years) were submitted to laser haemorrhoidoplasty with a 1470 nm diode laser in the centre for minimally invasive proctology in Siegen District Hospital...
November 29, 2017: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/29170839/transanal-hemorrhoidal-dearterialization-thd-for-hemorrhoidal-disease-a-single-center-study-on-1000-consecutive-cases-and-a-review-of-the-literature
#16
Carlo Ratto, Paola Campennì, Francesco Papeo, Lorenza Donisi, Francesco Litta, Angelo Parello
BACKGROUND: The transanal hemorrhoidal dearterialization (THD) Doppler procedure is a minimally invasive technique to treat symptomatic hemorrhoids. The aim of the study was to assess the clinical efficacy and the satisfaction of patients in a large series treated with THD and to review the relevant literature. METHODS: In this retrospective, single-institution, study consecutive patients with grade 2, 3, or 4 hemorrhoidal disease were treated with the THD Doppler procedure...
December 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/29154802/microrna-profiling-in-mda-mb-231-human-breast-cancer-cell-exposed-to-the-phaleria-macrocarpa-boerl-fruit-ethyl-acetate-fraction-pmeaf-through-iilumina-hi-seq-technologies-and-various-in-silico-bioinformatics-tools
#17
Nowroji Kavitha, Soundararajan Vijayarathna, Shanmugapriya, Chern Ein Oon, Yeng Chen, Jagat R Kanwar, Vasu Punj, Sreenivasan Sasidharan
ETHNOPHARMACOLOGICAL RELEVANCE: Phaleria macrocarpa (Scheff) Boerl, is a famous traditional medicinal plant which exhibited cytotoxicity against various cancerous cells. Traditionally, P. macrocarpa has been used to control cancer, impotency, hemorrhoids, diabetes mellitus, allergies, liver and heart disease, kidney disorders, blood diseases, acne, stroke, migraine, and various skin diseases. AIM OF THE STUDY: Recent studies have demonstrated a potent anticancer potential of P...
March 1, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29131098/implementation-of-a-new-high-volume-circular-stapler-in-stapled-anopexy-for-hemorrhoidal-disease-is-patient-s-short-term-outcome-affected-by-a-higher-volume-of-resected-tissue
#18
Brechtje A Grotenhuis, Joost Nonner, Eelco J R de Graaf, Pascal G Doornebosch
BACKGROUND: Stapled anopexy is a safe technique for the treatment of hemorrhoids but carries a higher risk of recurrence, which might be caused due to the limited volume of resected tissue. In this study, we investigated the introduction of a high-volume circular stapling device; in particular whether an increased amount of resected tissue could affect patients' short-term postoperative outcome. METHODS: Between 2011 and 2015, stapled anopexy was performed for hemorrhoids and/or anal prolapse in 141 patients (n = 25 conventional PPH-3©-stapler versus n = 116 high-volume CHEX©-stapler)...
November 2, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/29124622/medicinal-plants-with-antithrombotic-property-in-persian-medicine-a-mechanistic-review
#19
REVIEW
Zahra Memariani, Reihaneh Moeini, Shokooh Sadat Hamedi, Narjes Gorji, Seyyed Ali Mozaffarpur
Thrombosis is one of the major causes of morbidity and mortality in a wide range of vessels diseases. Due to the high prevalence of thromboembolic disorders investigations are being carried out on new antithrombotic agents with limited adverse side effects in which herbal medicines are considered as alternative remedies. Persian medicine (PM) as a traditional medicine has a good potential for pharmacotherapy based on its own principles and development of drugs via investigating PM literature. In PM manuscripts there are some concepts that express the management of blood clots and antithrombotic properties...
January 2018: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/29076869/hemorrhoids-what-are-the-options-in-2018
#20
Danny O Jacobs
PURPOSE OF REVIEW: Efforts continue to improve the treatment of patients with symptomatic hemorrhoidal disease by interventions designed to improve efficiency and effectiveness, including by reducing intraoperative and postoperative pain, decreasing operating times, minimizing blood loss and controlling symptoms and recurrence rates. Simultaneously, there are also renewed efforts to minimize the number of patients who will require procedural intervention by focusing on conservative measures that encourage better bowel regulation and habits...
January 2018: Current Opinion in Gastroenterology
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