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Masahiro Hashizume

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https://www.readbyqxmd.com/read/27893089/photoacoustic-mammography-capable-of-simultaneously-acquiring-photoacoustic-and-ultrasound-images
#1
Yasufumi Asao, Yohei Hashizume, Takahiro Suita, Ken-Ichi Nagae, Kazuhiko Fukutani, Yoshiaki Sudo, Toshikazu Matsushita, Shuichi Kobayashi, Mariko Tokiwa, Iku Yamaga, Elham Fakhrejahani, Masae Torii, Masahiro Kawashima, Masahiro Takada, Shotaro Kanao, Masako Kataoka, Tsuyoshi Shiina, Masakazu Toi
No abstract text is available yet for this article.
November 1, 2016: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/27833062/seasonal-analysis-of-the-short-term-effects-of-air-pollution-on-daily-mortality-in-northeast-asia
#2
Satbyul Estella Kim, Yasushi Honda, Masahiro Hashizume, Haidong Kan, Youn-Hee Lim, Hyewon Lee, Clara Tammy Kim, Seung-Muk Yi, Ho Kim
The constituents and concentrations of pollutants, individual exposures, and biologic responses to air pollution may vary by season and meteorological conditions. However, evidence regarding seasonality of the acute effects of air pollution on mortality is limited and inconsistent. Herein, we examined seasonal patterns in the short-term associations of particulate matter (PM) smaller than 10μm (PM10) with daily mortality in 29 cities of three northeast Asian countries. Stratified time-series models were used to determine whether season altered the effect of PM10 on mortality...
November 7, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27771246/protective-effects-of-estrogen-against-vascular-calcification-via-estrogen-receptor-%C3%AE-dependent-growth-arrest-specific-gene-6-transactivation
#3
Michiko Nanao-Hamai, Bo-Kyung Son, Tsuyoshi Hashizume, Sumito Ogawa, Masahiro Akishita
Vascular calcification is one of the major complications of cardiovascular disease and is an independent risk factor for myocardial infarction and cardiac death. Postmenopausal women have a higher prevalence of vascular calcification compared with premenopausal women, suggesting protective effects of estrogen (E2). However, the underlying mechanisms of its beneficial effects remain unclear. In the present study, we examined the inhibitory effects of E2 on vascular smooth muscle cell (VSMC) calcification, and found that growth arrest-specific gene 6 (Gas6), a crucial molecule in vascular calcification, is transactivated by estrogen receptor α (ERα) in response to E2...
October 19, 2016: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/27746294/molecular-evolution-of-respiratory-syncytial-virus-subgroup-a-genotype-na1-and-on1-attachment-glycoprotein-g-gene-in-central-vietnam
#4
Keisuke Yoshihara, Minh Nhat Le, Koo Nagasawa, Hiroyuki Tsukagoshi, Hien Anh Nguyen, Michiko Toizumi, Hiroyuki Moriuchi, Masahiro Hashizume, Koya Ariyoshi, Duc Anh Dang, Hirokazu Kimura, Lay-Myint Yoshida
We performed molecular evolutionary analyses of the G gene C-terminal 3rd hypervariable region of RSV-A genotypes NA1 and ON1 strains from the paediatric acute respiratory infection patients in central Vietnam during the 2010-2012 study period. Time-scaled phylogenetic analyses were performed using Bayesian Markov Chain Monte Carlo (MCMC) method, and pairwise distances (p-distances) were calculated. Bayesian Skyline Plot (BSP) was constructed to analyze the time-trend relative genetic diversity of central Vietnam RSV-A strains...
November 2016: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/27628555/-a-case-of-her2-positive-stage-iv-advanced-gastric-cancer-treated-with-chemotherapy-combined-with-trastuzumab
#5
Kai Takaya, Ryosuke Takahashi, Satoru Honma, Shinichiro Horii, Hirokazu Takahashi, Motohisa Hagiwara, Masahiro Chin, Eiji Hashizume
We report a case of human epidermal growth factor receptor(HER)2 positive stage IV advanced gastric cancer successfully treated with chemotherapy combined with trastuzumab. A 50-year-old man was diagnosed with type 3 gastric cancer complicated by liver and lymph node metastases. Owing to a HER2 immunohistochemistry tumor score of 3+, we initiated capecitabine plus CDDP plus trastuzumab chemotherapy. After 6 chemotherapy courses, computed tomography showed the liver metastasis had disappeared and the paraaortic lymph nodes had shrunk...
September 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/27553707/monosynaptic-facilitation-of-group-i-afferents-between-brachioradialis-and-extensor-carpi-radialis-in-humans
#6
Katsuhiro Shinozaki, Mitsuhiro Nito, Shinji Kobayashi, Masahiro Hayashi, Takuji Miyasaka, Wataru Hashizume, Masaomi Shindo, Akira Naito
Spinal reflex arcs mediated by low-threshold (group I) afferents from muscle spindles and Golgi tendon organs modulate motoneuron excitabilities to coordinate smooth movements. In this study, the reflex arcs between the brachioradialis (BR) and extensor carpi radialis muscles (ECR) were examined in nine healthy human subjects using a post-stimulus time-histogram method. Electrical conditioning stimuli (ES) to the radial nerve branches innervating BR (BR nerve) and ECR (ECR nerve) with the intensity just below the motor threshold were delivered and firings of the ECR and BR motor units were recorded in 6 and 7 of the nine subjects, respectively...
August 20, 2016: Neuroscience Research
https://www.readbyqxmd.com/read/27524928/associations-between-malaria-and-local-and-global-climate-variability-in-five-regions-in-papua-new-guinea
#7
Chisato Imai, Hae-Kwan Cheong, Ho Kim, Yasushi Honda, Jin-Hee Eum, Clara T Kim, Jin Seob Kim, Yoonhee Kim, Swadhin K Behera, Mohd Nasir Hassan, Joshua Nealon, Hyenmi Chung, Masahiro Hashizume
BACKGROUND: Malaria is a significant public health issue in Papua New Guinea (PNG) as the burden is among the highest in Asia and the Pacific region. Though PNG's vulnerability to climate change and sensitivity of malaria mosquitoes to weather are well-documented, there are few in-depth epidemiological studies conducted on the potential impacts of climate on malaria incidence in the country. METHODS: This study explored what and how local weather and global climate variability impact on malaria incidence in five regions of PNG...
2016: Tropical Medicine and Health
https://www.readbyqxmd.com/read/27485898/diarrheal-diseases-and-climate-change-in-cambodia-environmental-epidemiology-and-opportunities-for-adaptation
#8
Lachla J McIver, Chisato Imai, Petra G Buettner, Paul Gager, Vibol S Chan, Masahiro Hashizume, Steven N Iddings, Hero Kol, Piseth P Raingsey, K Lyne
The DRIP-SWICCH (Developing Research and Innovative Policies Specific to the Water-related Impacts of Climate Change on Health) project aimed to increase the resilience of Cambodian communities to the health risks posed by climate change-related impacts on water. This article follows a review of climate change and water-related diseases in Cambodia and presents the results of a time series analysis of monthly weather and diarrheal disease data for 11 provinces. In addition, correlations of diarrheal disease incidence with selected demographic, socioeconomic, and water and sanitation indicators are described, with results suggesting education and literacy may be most protective against disease...
August 2, 2016: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/27398063/new-era-for-tropical-medicine-and-health
#9
Masahiro Hashizume
No abstract text is available yet for this article.
2016: Tropical Medicine and Health
https://www.readbyqxmd.com/read/27374138/the-tohoku-medical-megabank-project-design-and-mission
#10
Shinichi Kuriyama, Nobuo Yaegashi, Fuji Nagami, Tomohiko Arai, Yoshio Kawaguchi, Noriko Osumi, Masaki Sakaida, Yoichi Suzuki, Keiko Nakayama, Hiroaki Hashizume, Gen Tamiya, Hiroshi Kawame, Kichiya Suzuki, Atsushi Hozawa, Naoki Nakaya, Masahiro Kikuya, Hirohito Metoki, Ichiro Tsuji, Nobuo Fuse, Hideyasu Kiyomoto, Junichi Sugawara, Akito Tsuboi, Shinichi Egawa, Kiyoshi Ito, Koichi Chida, Tadashi Ishii, Hiroaki Tomita, Yasuyuki Taki, Naoko Minegishi, Naoto Ishii, Jun Yasuda, Kazuhiko Igarashi, Ritsuko Shimizu, Masao Nagasaki, Seizo Koshiba, Kengo Kinoshita, Soichi Ogishima, Takako Takai-Igarashi, Teiji Tominaga, Osamu Tanabe, Noriaki Ohuchi, Toru Shimosegawa, Shigeo Kure, Hiroshi Tanaka, Sadayoshi Ito, Jiro Hitomi, Kozo Tanno, Motoyuki Nakamura, Kuniaki Ogasawara, Seiichiro Kobayashi, Kiyomi Sakata, Mamoru Satoh, Atsushi Shimizu, Makoto Sasaki, Ryujin Endo, Kenji Sobue, The Tohoku Medical Megabank Project Study Group, Masayuki Yamamoto
The Great East Japan Earthquake (GEJE) and resulting tsunami of March 11, 2011 gave rise to devastating damage on the Pacific coast of the Tohoku region. The Tohoku Medical Megabank Project (TMM), which is being conducted by Tohoku University Tohoku Medical Megabank Organization (ToMMo) and Iwate Medical University Iwate Tohoku Medical Megabank Organization (IMM), has been launched to realize creative reconstruction and to solve medical problems in the aftermath of this disaster. We started two prospective cohort studies in Miyagi and Iwate Prefectures: a population-based adult cohort study, the TMM Community-Based Cohort Study (TMM CommCohort Study), which will recruit 80 000 participants, and a birth and three-generation cohort study, the TMM Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study), which will recruit 70 000 participants, including fetuses and their parents, siblings, grandparents, and extended family members...
September 5, 2016: Journal of Epidemiology
https://www.readbyqxmd.com/read/27306333/association-of-rsv-a-on1-genotype-with-increased-pediatric-acute-lower-respiratory-tract-infection-in-vietnam
#11
Keisuke Yoshihara, Minh Nhat Le, Michiko Okamoto, Anita Carolle Akpeedje Wadagni, Hien Anh Nguyen, Michiko Toizumi, Enga Pham, Motoi Suzuki, Ai Thi Thuy Nguyen, Hitoshi Oshitani, Koya Ariyoshi, Hiroyuki Moriuchi, Masahiro Hashizume, Duc Anh Dang, Lay-Myint Yoshida
Since the initial discovery of RSV-A ON1 in Canada in 2010, ON1 has been reported worldwide, yet information regarding its clinical impact and severity has been controversial. To investigate the clinical relevance of RSV-A ON1,acute respiratory infection (ARI) cases enrolled to our population-based prospective pediatric ARI surveillance at Khanh Hoa General Hospital, Central Vietnam from January 2010 through December 2012 were studied. Clinical-epidemiological information and nasopharyngeal samples were collected...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27258598/temperature-variability-and-mortality-a-multi-country-study
#12
Yuming Guo, Antonio Gasparrini, Ben G Armstrong, Benjawan Tawatsupa, Aurelio Tobias, Eric Lavigne, Micheline de Sousa Zanotti Stagliorio Coelho, Xiaochuan Pan, Ho Kim, Masahiro Hashizume, Yasushi Honda, Yue Leon Guo, Chang-Fu Wu, Antonella Zanobetti, Joel D Schwartz, Michelle L Bell, Ala Overcenco, Kornwipa Punnasiri, Shanshan Li, Linwei Tian, Paulo Saldiva, Gail Williams, Shilu Tong
BACKGROUND: The evidence and method are limited for the associations between mortality and temperature variability (TV) within or between days. OBJECTIVES: We developed a novel method to calculate TV and investigated TV-mortality associations using a large multicountry data set. METHODS: We collected daily data for temperature and mortality from 372 locations in 12 countries/regions (Australia, Brazil, Canada, China, Japan, Moldova, South Korea, Spain, Taiwan, Thailand, the United Kingdom, and the United States)...
October 2016: Environmental Health Perspectives
https://www.readbyqxmd.com/read/27188948/changes-in-susceptibility-to-heat-during-the-summer-a-multicountry-analysis
#13
Antonio Gasparrini, Yuming Guo, Masahiro Hashizume, Eric Lavigne, Aurelio Tobias, Antonella Zanobetti, Joel D Schwartz, Michela Leone, Paola Michelozzi, Haidong Kan, Shilu Tong, Yasushi Honda, Ho Kim, Ben G Armstrong
Few studies have examined the variation in mortality risk associated with heat during the summer. Here, we apply flexible statistical models to investigate the issue by using a large multicountry data set. We collected daily time-series data of temperature and mortality from 305 locations in 9 countries, in the period 1985-2012. We first estimated the heat-mortality relationship in each location with time-varying distributed lag non-linear models, using a bivariate spline to model the exposure-lag-response over lag 0-10...
June 1, 2016: American Journal of Epidemiology
https://www.readbyqxmd.com/read/27180931/asian-dust-and-pediatric-emergency-department-visits-due-to-bronchial-asthma-and-respiratory-diseases-in-nagasaki-japan
#14
Takahiro Nakamura, Masahiro Hashizume, Kayo Ueda, Atsushi Shimizu, Ayano Takeuchi, Tatsuhiko Kubo, Kunio Hashimoto, Hiroyuki Moriuchi, Hiroshi Odajima, Tasuku Kitajima, Kasumi Tashiro, Kunio Tomimasu, Yuji Nishiwaki
BACKGROUND: The adverse health effects of Asian dust (AD) on the respiratory system of children are unclear. We hypothesized that AD events may lead to increased visits by children to emergency medical centers due to bronchial asthma and respiratory diseases, including bronchial asthma. METHODS: We used anonymized data on children receiving primary emergency treatment at Nagasaki Municipal Primary Emergency Medical Center, Japan between March 2010 and September 2013...
May 14, 2016: Journal of Epidemiology
https://www.readbyqxmd.com/read/27136571/the-role-of-influenza-in-the-delay-between-low-temperature-and-ischemic-heart-disease-evidence-from-simulation-and-mortality-data-from-japan
#15
Chisato Imai, Adrian G Barnett, Masahiro Hashizume, Yasushi Honda
Many studies have found that cardiovascular deaths mostly occur within a few days of exposure to heat, whereas cold-related deaths can occur up to 30 days after exposure. We investigated whether influenza infection could explain the delayed cold effects on ischemic heart diseases (IHD) as they can trigger IHD. We hypothesized two pathways between cold exposure and IHD: a direct pathway and an indirect pathway through influenza infection. We created a multi-state model of the pathways and simulated incidence data to examine the observed delayed patterns in cases...
2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/26996830/oligosynaptic-inhibition-of-group-i-afferents-between-the-brachioradialis-and-flexor-carpi-radialis-in-humans
#16
Shinji Kobayashi, Masahiro Hayashi, Katsuhiro Shinozaki, Mitsuhiro Nito, Wataru Hashizume, Takuji Miyasaka, Masaomi Shindo, Akira Naito
Spinal reflex arcs mediated by low threshold afferents between the brachioradialis (BR) and flexor carpi radialis (FCR) were studied in eleven healthy human subjects using a post-stimulus time-histogram method. Electrical conditioning stimuli (ES) to the radial nerve branch innervating BR with the intensity below the motor threshold (MT) induced an early and significant trough (inhibition) in 32/85 FCR motor units (MUs) in 9/9 subjects. Such inhibition was never provoked by cutaneous stimulation. The central synaptic delay (CSD) of the inhibition was approximately 1...
September 2016: Neuroscience Research
https://www.readbyqxmd.com/read/26983704/the-role-of-time-resolved-mra-for-post-treatment-assessment-of-pulmonary-arteriovenous-malformations-a-pictorial-essay
#17
Tatsuya Kawai, Masashi Shimohira, Kengo Ohta, Takuya Hashizume, Masahiro Muto, Kazushi Suzuki, Kenichiro Kurosaka, Yuta Shibamoto
No abstract text is available yet for this article.
July 2016: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/26955944/effects-of-weather-factors-on-dengue-fever-incidence-and-implications-for-interventions-in-cambodia
#18
Youngjo Choi, Choon Siang Tang, Lachlan McIver, Masahiro Hashizume, Vibol Chan, Rabindra Romauld Abeyasinghe, Steven Iddings, Rekol Huy
BACKGROUND: Dengue viruses and their mosquito vectors are sensitive to their environment. Temperature, rainfall and humidity have well-defined roles in the transmission cycle. Therefore changes in these conditions may contribute to increasing incidence. The aim of this study was to examine the relationship between weather factors and dengue incidence in three provinces in Cambodia, in order to strengthen the evidence basis of dengue control strategies in this high-burden country. METHODS: We developed negative binomial models using monthly average maximum, minimum, mean temperatures and monthly cumulative rainfall over the period from January 1998 to December 2012...
March 8, 2016: BMC Public Health
https://www.readbyqxmd.com/read/26913061/behavioral-medicine-in-teikyo-university-and-toho-university
#19
REVIEW
Takeaki Takeuchi, Masahiro Hashizume
Behavioral medicine has increased in importance to become a promising field in medical education. The Teikyo University Graduate School of Public Health and Toho University School of Medicine were evaluated in terms of their educational emphasis on behavioral medicine. The Teikyo University Graduate School of Public Health has the following five core requirements, as in the global standards: behavioral medicine, biostatistics, epidemiology, occupational health, and health policy management. Behavioral medicine mainly encompasses psychology in normal populations, working as a gateway to the medical world among non-medical professionals who are interested in medicine...
2016: BioPsychoSocial Medicine
https://www.readbyqxmd.com/read/26891307/effect-of-climate-factors-on-the-childhood-pneumonia-in-papua-new-guinea-a-time-series-analysis
#20
Jinseob Kim, Jong-Hun Kim, Hae-Kwan Cheong, Ho Kim, Yasushi Honda, Mina Ha, Masahiro Hashizume, Joel Kolam, Kasis Inape
This study aimed to assess the association between climate factors and the incidence of childhood pneumonia in Papua New Guinea quantitatively and to evaluate the variability of the effect size according to their geographic properties. The pneumonia incidence in children under five-year and meteorological factors were obtained from six areas, including monthly rainfall and the monthly average daily maximum temperatures during the period from 1997 to 2006 from national health surveillance data. A generalized linear model was applied to measure the effect size of local and regional climate factor...
February 2016: International Journal of Environmental Research and Public Health
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