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JOURNAL ARTICLE
Tetsushi Nakagawa, Yuji Yamamoto, Senichiro Yanagawa, Shohei Shiozaki, Yuuki Kaneko, Atsuhiro Watanabe, Mai Nishina, Daisuke Takei, Yusuke Sumi, Minoru Yamaki, Manabu Kurayoshi, Junji Hashizume, Akihiko Oshita, Masahiro Nakahara, Toshio Noriyuki
A 67-year-old man visited our hospital for epigastric pain. Esophagogastroduodenoscopy(EGD)revealed type 2 gastric cancer from the cardia to the gastric angle, and histopathological examination revealed papillary adenocarcinoma(pap), HER2-positive. Contrast-enhanced CT showed wall thickening mainly in the posterior wall of the gastric body, enlarged lymph nodes that were lumped together with the main lesion, and 8 low-absorption areas with ring shaped contrast effects in both lobes of the liver. The patient was diagnosed as gastric cancer cT4aN(+)M1[HEP], clinical Stage ⅣB...
April 2024: Gan to Kagaku Ryoho. Cancer & Chemotherapy
#2
JOURNAL ARTICLE
Lisa Yamasaki, Takuma Kamada, Chris Fook Sheng Ng, Yuya Takane, Ko Nakajima, Kazuki Yamaguchi, Kazutaka Oka, Yasushi Honda, Yoonhee Kim, Masahiro Hashizume
BACKGROUND: Air conditioners can prevent heat-related illness and mortality, but the increased use of air conditioners may enhance susceptibility to heat-related illnesses during large-scale power failures. Here, we examined the risks of heat-related illness ambulance transport (HIAT) and mortality associated with typhoon-related electricity reduction (ER) in the summer months in the Tokyo metropolitan area. METHODS: We conducted event study analyses to compare temperature-HIAT and mortality associations before and after the power outage (July to September 2019)...
April 2024: Environmental Epidemiology
#3
JOURNAL ARTICLE
Yasuko Mano, Lei Yuan, Chris Fook Sheng Ng, Masahiro Hashizume
BACKGROUND: Although the effects of temperature on genitourinary morbidity and mortality have been investigated in several countries, it remains largely unexplored in Japan. We investigated the association between ambient temperature and genitourinary emergency ambulance dispatches (EADs) in Japan and the modifying roles of sex, age, and illness severity. METHODS: We conducted a time-stratified case-crossover study with conditional quasi-Poisson regression to estimate the association between mean temperature and genitourinary EADs in all prefectures of Japan between 2015 and 2019...
April 2024: Environmental Epidemiology
#4
JOURNAL ARTICLE
Yoshiteru Katsura, Koji Hayashi, Satomi Sakai, Sakina Hashizume, Masahiro Koh, Akio Hara, Koki Tamai, Hiroshi Takeyama, Hajime Hirose, Natsumi Tanaka, Shu Okamura, Setsuko Yoshioka, Chikara Ebisui, Hideoki Yokouchi, Masahiko Yano
Lymphoepithelial cyst(LEC)of the pancreas is a relatively rare benign cystic disease of the pancreas. In this report, we describe a case of LEC in which a malignant tumor could not be ruled out by preoperative diagnosis and surgery was performed. The patient was a 72-year-old man. A simple CT scan of the chest and abdomen performed as a follow-up for another disease incidentally revealed a mass in the pancreatic tail. Enhanced CT of the abdomen showed a tumor approximately 3 cm in size at the pancreatic tail with no contrast effect...
March 2024: Gan to Kagaku Ryoho. Cancer & Chemotherapy
#5
JOURNAL ARTICLE
Kazuaki Hashimoto, Takeaki Takeuchi, Kazushige Ihara, Shuichi Obuchi, Hisashi Kawai, Hirohiko Hirano, Yoshinori Fujiwara, Kim Hunkyung, Yutaka Watanabe, Masahiro Hashizume
Social isolation among older adults affects their physical and mental health. Ego-resilience is associated with flexible adaptation to various environments and acceptable behaviors. However, its association with social isolation among older people is unclear. Therefore, a health survey was conducted with 510 adults aged 65 years or older to assess social isolation, its associated factors, and ego resilience. The results showed that the social isolation group had a lower median ego-resiliency scale score (42...
2024: Gerontology & Geriatric Medicine
#6
JOURNAL ARTICLE
Keriin Katsaros, Clemens Marggraf, Kristie L Ebi, Kareem Buyana, Masahiro Hashizume, Shih-Chun Candice Lung, Virginia Murray, Sokhna Thiam, Jo-Ting Huang-Lachmann
Challenges faced by many countries are energy insecurity, climate change, and the health and long-term care of growing numbers of older people. These challenges are increasingly intersecting with rising energy prices, aging populations, and an increased frequency and intensity of extreme climate events. This paper gives a deeper understanding of the current and predicted interconnections among these challenges through narrative-driven content and thematic analysis from workshops with a diverse group of international stakeholders from the Global North and Global South...
February 23, 2024: Maturitas
#7
JOURNAL ARTICLE
Nina G G Domingo, Arlene M Fiore, Jean-Francois Lamarque, Patrick L Kinney, Leiwen Jiang, Antonio Gasparrini, Susanne Breitner, Eric Lavigne, Joana Madureira, Pierre Masselot, Susana das Neves Pereira da Silva, Chris Fook Sheng Ng, Jan Kyselý, Yuming Guo, Shilu Tong, Haidong Kan, Aleš Urban, Hans Orru, Marek Maasikmets, Mathilde Pascal, Klea Katsouyanni, Evangelia Samoli, Matteo Scortichini, Massimo Stafoggia, Masahiro Hashizume, Barrak Alahmad, Magali Hurtado Diaz, César De la Cruz Valencia, Noah Scovronick, Rebecca M Garland, Ho Kim, Whanhee Lee, Aurelio Tobias, Carmen Íñiguez, Bertil Forsberg, Christofer Åström, Martina S Ragettli, Yue Leon Guo, Shih-Chun Pan, Valentina Colistro, Michelle Bell, Antonella Zanobetti, Joel Schwartz, Alexandra Schneider, Ana M Vicedo-Cabrera, Kai Chen
Short-term exposure to ground-level ozone in cities is associated with increased mortality and is expected to worsen with climate and emission changes. However, no study has yet comprehensively assessed future ozone-related acute mortality across diverse geographic areas, various climate scenarios, and using CMIP6 multi-model ensembles, limiting our knowledge on future changes in global ozone-related acute mortality and our ability to design targeted health policies. Here, we combine CMIP6 simulations and epidemiological data from 406 cities in 20 countries or regions...
February 16, 2024: One earth
#8
JOURNAL ARTICLE
Miho Sassa, Daisuke Yoneoka, Chris Fook Sheng Ng, Alton Quan Cao, Ganan Devanathan, Masahiro Hashizume, Shuhei Nomura
BACKGROUND: Intestinal parasitic infections pose a significant global public health issue, particularly among pregnant women, who are generally more susceptible due to their elevated need for iron and nutrients. Deworming stands as a secure and efficacious public health intervention. The World Health Organization (WHO) set a target for the national deworming coverage rate among pregnant women at 75% by 2030. Nonetheless, the existing body of evidence on deworming among pregnant women in low- and middle-income countries (LMICs) remains limited...
March 1, 2024: Journal of Global Health
#9
JOURNAL ARTICLE
Nahoko Harada, Masahide Koda, Akifumi Eguchi, Masahiro Hashizume, Motoi Suzuki, Shuhei Nomura
BACKGROUND: A key measure of the effectiveness of end-of-life care is the place of death. The COVID-19 pandemic affected end-of-life care and the circumstances of patients with dementia. METHODS: This observational, retrospective cohort study used Japanese national data to examine the numbers and locations of reported deaths among patients with dementia older than 65 years during the COVID-19 pandemic. Locations were grouped as medical institutions, nursing facilities, homes, or all the above...
February 24, 2024: Journal of Epidemiology
#10
JOURNAL ARTICLE
Zin Wai Htay, Chris Fook Sheng Ng, Yoonhee Kim, Youn-Hee Lim, Masao Iwagami, Masahiro Hashizume
BACKGROUND: Previous studies have indicated that renal disease mortality is sensitive to ambient temperatures. However, most have been limited to the summer season with inconclusive evidence for changes in population vulnerability over time. OBJECTIVE: This study aims to examine the association between short-term exposure to ambient temperatures and mortality due to renal diseases in Japan, and how this association varied over time. METHODS: We conducted a two-stage, time-stratified case-crossover study from 1979 to 2019 across 47 prefectures of Japan...
February 2024: Environmental Epidemiology
#11
JOURNAL ARTICLE
Lina Madaniyazi, Ben Armstrong, Aurelio Tobias, Malcolm N Mistry, Michelle L Bell, Aleš Urban, Jan Kyselý, Niilo Ryti, Ivana Cvijanovic, Chris Fook Sheng Ng, Dominic Roye, Ana Maria Vicedo-Cabrera, Shilu Tong, Eric Lavigne, Carmen Íñiguez, Susana das Neves Pereira da Silva, Joana Madureira, Jouni J K Jaakkola, Francesco Sera, Yasushi Honda, Antonio Gasparrini, Masahiro Hashizume
BACKGROUND: Climate change can directly impact temperature-related excess deaths and might subsequently change the seasonal variation in mortality. In this study, we aimed to provide a systematic and comprehensive assessment of potential future changes in the seasonal variation, or seasonality, of mortality across different climate zones. METHODS: In this modelling study, we collected daily time series of mean temperature and mortality (all causes or non-external causes only) via the Multi-Country Multi-City Collaborative (MCC) Research Network...
February 2024: Lancet. Planetary Health
#12
JOURNAL ARTICLE
Yo Akazawa, Hajime Hirose, Shu Okamura, Hiroshi Takeyama, Risa Kawamoto, Narumi Sawamura, Satomi Sakai, Sakina Hashizume, Masahiro Koh, Koji Hayashi, Akio Hara, Yoshiteru Katsura, Setsuko Yoshioka, Chikara Ebisui, Masahiko Yano
A 77-year-old female patient presented with a medical history of 4 cancerous lesions, each with a surgical history. She was referred to our hospital due to anemia. Upon examination, she was diagnosed with transverse colon cancer. Duodenal invasion was suspected, which made performing R0 surgery difficult; therefore, the NAC approach was chosen. Three courses of CAPOX were administered, resulting in tumor obstruction, leading to the formation of an ileum stoma. MSI testing revealed MSI-H, and pembrolizumab treatment was initiated...
December 2023: Gan to Kagaku Ryoho. Cancer & Chemotherapy
#13
JOURNAL ARTICLE
Yuki Fukami, Masahiro Iijima, Haruki H Koike, Satoru Yagi, Soma Furukawa, Naohiro Mouri, Jun Ouchida, Ayuka Murakami, Madoka Iida, Satoshi Yokoi, Atsushi Hashizume, Yohei Iguchi, Shiro Imagama, Masahisa Katsuno
BACKGROUND AND OBJECTIVES: This study aimed to identify disease-related autoantibodies in the serum of patients with immune-mediated neuropathies including chronic inflammatory demyelinating polyneuropathy (CIDP) and to investigate the clinical characteristics of patients with these antibodies. METHODS: Proteins extracted from mouse brain tissue were used to react with sera from patients with CIDP by western blotting (WB) to determine the presence of common bands...
March 2024: Neurology® Neuroimmunology & Neuroinflammation
#14
JOURNAL ARTICLE
Hitomi Hinata, Kaung Suu Lwin, Akifumi Eguchi, Cyrus Ghaznavi, Masahiro Hashizume, Shuhei Nomura
BACKGROUND: Globally, women experience healthcare inequalities, which may contribute to excessive mortality rates at various stages of their lives. Though Bangladesh has achieved excellent progress in providing healthcare, the country still has some critical challenges that need immediate attention. The objective of this study is to examine the association between social determinants and barriers to accessing healthcare among ever-married women aged 15-49 in Bangladesh. METHODS: The study was conducted among 20,127 women aged 15-49, using data from the 2017-2018 Bangladesh Demographic and Health Survey...
2024: PloS One
#15
JOURNAL ARTICLE
Micheal T Pillay, Noboru Minakawa, Yoonhee Kim, Nyakallo Kgalane, Jayanthi V Ratnam, Swadhin K Behera, Masahiro Hashizume, Neville Sweijd
Climatic factors influence malaria transmission via the effect on the Anopheles vector and Plasmodium parasite. Modelling and understanding the complex effects that climate has on malaria incidence can enable important early warning capabilities. Deep learning applications across fields are proving valuable, however the field of epidemiological forecasting is still in its infancy with a lack of applied deep learning studies for malaria in southern Africa which leverage quality datasets. Using a novel high resolution malaria incidence dataset containing 23 years of daily data from 1998 to 2021, a statistical model and XGBOOST machine learning model were compared to a deep learning Transformer model by assessing the accuracy of their numerical predictions...
December 28, 2023: Scientific Reports
#16
JOURNAL ARTICLE
Takeaki Takeuchi, Kazuaki Hashimoto, Akiko Koyama, Keiko Asakura, Masahiro Hashizume
INTRODUCTION: Despite the acknowledged interconnection between smoking and pain, research on the relationship between smoking and central sensitization (CS) is scarce; this pain mechanism has attracted recent research attention. Considering potential sex differences, this cross-sectional study aimed to investigate the association between smoking and CS. METHODS: Overall, 415 adult participants from an outpatient clinic underwent evaluation. The analysis focused on determining the relationship between smoking status and CS by differentiating between sexes...
2023: Tobacco Induced Diseases
#17
REVIEW
Yoonhee Kim, Kazutaka Oka, Erin C Kawazu, Chris Fook Sheng Ng, Xerxes Seposo, Kayo Ueda, Masahiro Hashizume, Yasushi Honda
Climate change poses significant threats to human health, propelling Japan to take decisive action through the Climate Change Adaptation Act of 2018. This Act has led to the implementation of climate change adaptation policies across various sectors, including healthcare. In this review, we synthesized existing scientific evidence on the impacts of climate change on health in Japan and outlined the adaptation strategies and measures implemented by the central and local governments. The country has prioritized tackling heat-related illness and mortality and undertaken various adaptation measures to mitigate these risks...
November 2023: The Lancet Regional Health. Western Pacific
#18
JOURNAL ARTICLE
Jieun Min, Duk-Hee Kang, Cinoo Kang, Michelle L Bell, Ho Kim, Juyeon Yang, Antonio Gasparrini, Eric Lavigne, Masahiro Hashizume, Yoonhee Kim, Chris Fook Sheng Ng, Yasushi Honda, Susana das Neves Pereira da Silva, Joana Madureira, Yue Leon Guo, Shih-Chun Pan, Ben Armstrong, Francesco Sera, Pierre Masselot, Joel Schwartz, Ana Maria Vicedo-Cabrera, Jung Pyo Lee, Ziyad Al-Aly, Jung Won Lee, Youngrin Kwag, Eunhee Ha, Whanhee Lee
BACKGROUND: Recent studies have reported that air pollution is related to kidney diseases. However, the global evidence on the risk of death from acute kidney injury (AKI) owing to air pollution is limited. Therefore, we investigated the association between short-term exposure to air pollution-particulate matter ≤ 2.5 μm (PM2.5 ), ozone (O3 ), and nitrogen dioxide (NO2 )-and AKI-related mortality using a multi-country dataset. METHODS: This study included 41,379 AKI-related deaths in 136 locations in six countries during 1987-2018...
December 2, 2023: Environment International
#19
JOURNAL ARTICLE
Lei Yuan, Lina Madaniyazi, Ana M Vicedo-Cabrera, Yasushi Honda, Chris Fook Sheng Ng, Kayo Ueda, Kazutaka Oka, Aurelio Tobias, Masahiro Hashizume
BACKGROUND: The impact of temperature on morbidity remains largely unknown. Moreover, extensive evidence indicates contrasting patterns between temperature-mortality and temperature-morbidity associations. A nationwide comparison of the impact of temperature on mortality and morbidity in more specific subgroups is necessary to strengthen understanding and help explore underlying mechanisms by identifying susceptible populations. OBJECTIVE: We performed this study to quantify and compare the impact of temperature on mortality and morbidity in 47 prefectures in Japan...
December 2023: Environmental Health Perspectives
#20
JOURNAL ARTICLE
Ramita Thawonmas, Masahiro Hashizume, Yoonhee Kim
BACKGROUND: The impact of climate change on mental health largely remains to be evaluated. Although growing evidence has reported a short-term association between suicide and temperature, future projections of temperature-attributable suicide have not been thoroughly examined. OBJECTIVES: We aimed to project the excess temperature-related suicide mortality in Japan under three climate change scenarios until the 2090s. METHODS: Daily time series of mean temperature and the number of suicide deaths in 1973-2015 were collected for 47 prefectures in Japan...
November 2023: Environmental Health Perspectives
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