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Mass gathering medicine

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https://www.readbyqxmd.com/read/28801789/multimodal-laser-ablation-desorption-imaging-analysis-of-zn-and-mmp-11-in-breast-tissues
#1
Raquel González de Vega, María Luisa Fernández Sanchez, Noemí Eiro, Francisco J Vizoso, Michael Sperling, Uwe Karst, Alfredo Sanz Medel
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases. The main functions of these metalloproteinases are the degradation of the stromal connective tissue and basement membrane components. Recent data from model systems suggest that MMPs are involved in breast cancer (BC) initiation, invasion, and metastasis. Particularly, MMP-11 (stromelysin-3) is expressed in stromal fibroblasts adjacent to epithelial tumor cells, and high levels of this metalloproteinase were associated with tumor progression and poor prognosis of BC...
August 12, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28794234/deep-immune-profiling-of-an-arginine-enriched-nutritional-intervention-in-patients-undergoing-surgery
#2
Nima Aghaeepour, Cindy Kin, Edward A Ganio, Kent P Jensen, Dyani K Gaudilliere, Martha Tingle, Amy Tsai, Hope L Lancero, Benjamin Choisy, Leslie S McNeil, Robin Okada, Andrew A Shelton, Garry P Nolan, Martin S Angst, Brice L Gaudilliere
Application of high-content immune profiling technologies has enormous potential to advance medicine. Whether these technologies reveal pertinent biology when implemented in interventional clinical trials is an important question. The beneficial effects of preoperative arginine-enriched dietary supplements (AES) are highly context specific, as they reduce infection rates in elective surgery, but possibly increase morbidity in critically ill patients. This study combined single-cell mass cytometry with the multiplex analysis of relevant plasma cytokines to comprehensively profile the immune-modifying effects of this much-debated intervention in patients undergoing surgery...
August 9, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28701045/investigating-chemical-composition-and-indications-of-hydrosol-soft-drinks-aromatic-waters-used-in-persian-folk-medicine-for-women-s-hormonal-and-reproductive-health-conditions
#3
Azadeh Hamedi, Mehdi Afifi, Hamed Etemadfard
Hydrosol soft drinks in Persian nutrition culture are produced as side products of the essential oil industry to be used as safe remedies for treatment of some ailments. This study investigated hydrosols for women's hormonal health conditions. Detailed information was gathered by questionnaires. Chemical constituents of these mono- or poly-herbal hydrosols were identified after liquid/liquid extraction and gas chromatography-mass spectrometry. Hierarchical cluster and K-means analysis (SPSS software) were used to find their relevance...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/28698062/the-clandestine-multiple-graves-in-malaysia-the-first-mass-identification-operation-of-human-skeletal-remains
#4
Mohd Suhani Mohd Noor, Lay See Khoo, Wan Zafirah Zamaliana Alias, Ahmad Hafizam Hasmi, Mohamad Azaini Ibrahim, Mohd Shah Mahmood
The first ever mass identification operation of skeletal remains conducted for the clandestine graves in Malaysia consisted of 165 individuals unearthed from 28 human trafficking transit camps located in Wang Kelian, along the Thai-Malaysia border. A DVI response was triggered in which expert teams comprising of pathologists, anthropologists, odontologists, radiologists and DNA experts were gathered at the identified operation centre. The Department of Forensic Medicine, Hospital Sultanah Bahiyah, Alor Star, Kedah, located approximately 75km away from Wang Kelian, was temporarily converted into a victim identification centre (VIC) as it is the nearest available forensic facility to the mass grave site...
September 2017: Forensic Science International
https://www.readbyqxmd.com/read/28668659/morbidity-and-mortality-amongst-indian-hajj-pilgrims-a-3-year-experience-of-indian-hajj-medical-mission-in-mass-gathering-medicine
#5
Inam D Khan, Shahbaz A Khan, Bushra Asima, Syed B Hussaini, M Zakiuddin, F A Faisal
The Hajj, a mass-gathering of over 3.5-million pilgrims, faces challenges to global health-security, housing, food, water, transportation, communication, sanitation, crowd-control and security. The Indian Medical Mission extended health-security to approximately 140,000 pilgrims, through outreach medical teams, primary-care clinics, tent-clinics, secondary-care hospitals and evacuation capabilities. Data on medical attendance, bed-occupancy, investigations, referrals, medication usage and deaths was compared...
June 28, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/28590773/factors-influencing-brown-fat-activation-in-fdg-pet-ct-a-retrospective-analysis-of-15-000-cases
#6
Jeffrey D Steinberg, Wouter Vogel, Erik Vegt
OBJECTIVE: Brown fat can exhibit high uptake of fluorine-18 fludeoxyglucose ((18)F-FDG) on positron emission tomography (PET) and interferes with interpretation of the scan. The goal of this study was to identify factors that may influence brown adipose tissue (BAT) activation. METHODS: A retrospective study of (18)F-FDG PET scans was performed using a database of 15,109 PET/CT reports. BAT activation reported by nuclear medicine physicians and factors influencing BAT activation were gathered...
July 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28314284/altered-levels-of-serum-ceramide-sphingosine-and-sphingomyelin-are-associated-with-colorectal-cancer-a-retrospective-pilot-study
#7
Duska Separovic, Anthony F Shields, Philip A Philip, Jacek Bielawski, Alicja Bielawska, Jason S Pierce, Adi L Tarca
BACKGROUND/AIM: Because patients with cancer of apparently equivalent stage often have different outcomes, it is necessary to gather additional information to complement cancer staging. Dysregulated sphingolipid metabolism contributes to carcinogenesis. In this retrospective pilot study, we tested the hypothesis that changes in serum levels of sphingolipids are associated with stage IV colorectal cancer (CRC). PATIENTS AND METHODS: We used commercially available serum samples from healthy males and patients with CRC (adenocarcinoma of the large intestine, stage IV with metastases)...
March 2017: Anticancer Research
https://www.readbyqxmd.com/read/28274288/improving-data-quality-in-mass-gatherings-health-research
#8
Andrew Guy, Ross Prager, Sheila Turris, Adam Lund
Mass gatherings attract large crowds and can strain the planning and health resources of the community, city, or nation hosting an event. Mass-Gatherings Health (MGH) is an evolving niche of prehospital care rooted in emergency medicine, emergency management, public health, and disaster medicine. To explore front-line issues related to data quality in the context of mass gatherings, the authors draw on five years of management experience with an online, mass-gathering event and patient registry, as well as clinical and operational experience amassed over several decades...
June 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28077609/travellers-and-influenza-risks-and-prevention
#9
REVIEW
M Goeijenbier, P van Genderen, B J Ward, A Wilder-Smith, R Steffen, A D M E Osterhaus
BACKGROUND: Influenza viruses are among the major causes of serious human respiratory tract infection worldwide. In line with the high disease burden attributable to influenza, these viruses play an important, but often neglected, role in travel medicine. Guidelines and recommendations regarding prevention and management of influenza in travellers are scarce. Of special interest for travel medicine are risk populations and also circumstances that facilitate influenza virus transmission and spread, like travel by airplane or cruise ship and mass gatherings...
January 2017: Journal of Travel Medicine
https://www.readbyqxmd.com/read/27978861/a-prospective-analysis-of-patients-presenting-for-medical-attention-at-a-large-electronic-dance-music-festival
#10
Matt S Friedman, Alex Plocki, Antonios Likourezos, Illya Pushkar, Andrew N Bazos, Christian Fromm, Benjamin W Friedman
Mass-Gathering Medicine studies have identified variables that predict greater patient presentation rates (PPRs) and transport to hospital rates (TTHRs). This is a descriptive report of patients who presented for medical attention at an annual electronic dance music festival (EDMF). At this large, single EDMF in New York City (NYC; New York, USA), the frequency of patient presentation, the range of presentations, and interventions performed were identified. This descriptive report examined consecutive patients who presented to the medical tent of a summertime EDMF held at an outdoor venue with an active, mobile, bounded crowd...
February 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/27646490/mass-gathering-medicine-risks-and-patient-presentations-at-a-2-day-electronic-dance-music-event-year-two
#11
Sheila A Turris, Michael Camporese, Samuel J Gutman, Adam Lund
Turris SA , Camporese M , Gutman SJ , Lund A . Mass-gathering medicine: risks and patient presentations at a 2-day electronic dance music event - year two. Prehosp Disaster Med. 2016;31(6):687-688.
December 2016: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/27613753/a-practical-approach-to-events-medicine-provision
#12
Susan P Smith, Joseph F Cosgrove, Peter J Driscoll, Andrew Smith, John Butler, Peter Goode, Carl Waldmann, Christopher J Vallis, Fiona Topham, Michael Monty Mythen
In the past three decades, mass casualty incidents have occurred worldwide at multiple sporting events and other mass gatherings. Organisational safety and healthcare provision can consequently be scrutinised post-event. Within the UK, such incidents in the 1980s provided incentives to improve medical services and subsequent high profile UK-based international sporting events (London Olympics and Paralympics 2012, Glasgow Commonwealth Games 2014, Rugby World Cup 2015) added a further catalyst for developing services...
August 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/27559845/a-career-in-a-kingdom-journeys-in-infection-mass-gathering-medicine-and-public-health-diplomacy
#13
Ziad Memish
No abstract text is available yet for this article.
March 4, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27497725/the-accuracy-of-body-mass-prediction-for-elderly-specimens-implications-for-paleoanthropology-and-legal-medicine
#14
Tony Chevalier, Philippe Lefèvre, Jan Pieter Clarys, Jean-Pol Beauthier
Different practices in paleoanthropology and legal medicine raise questions concerning the robustness of body mass (BM) prediction. Integrating personal identification from body mass estimation with skeleton is not a classic approach in legal medicine. The originality of our study is the use of an elderly sample in order to push prediction methods to their limits and to discuss about implications in paleoanthropology and legal medicine. The aim is to observe the accuracy of BM prediction in relation to the body mass index (BMI, index of classification) using five femoral head (FH) methods and one shaft (FSH) method...
October 2016: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/27262693/mass-gathering-medicine-hajj-pilgrimage-in-saudi-arabia-the-clinical-pattern-of-pneumonia-among-pilgrims-during-hajj
#15
Bader Hamza Shirah, Syed Husham Zafar, Olayan Ali Alferaidi, Abdul Momin Muhammad Sabir
The planned annual Hajj to the holy shrines in Makkah, Saudi Arabia, is recognized as one of the largest recurring religious mass gatherings globally, and the outbreak of infectious diseases is of major concern. We aim to study the incidence, etiology, risk factors, length of hospital stay, and mortality rate of pneumonia amongst pilgrims admitted to Al-Ansar general hospital, Madinah, Saudi Arabia during the Hajj period of December 2004-November 2013. A retrospective analysis of all patients diagnosed and admitted as pneumonia was done...
June 1, 2016: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/27212053/exploring-international-views-on-key-concepts-for-mass-gathering-health-through-a-delphi-process
#16
Malinda Steenkamp, Alison E Hutton, Jamie C Ranse, Adam Lund, Sheila A Turris, Ron Bowles, Katherine Arbuthnott, Paul A Arbon
Introduction The science underpinning mass-gathering health (MGH) is developing rapidly. However, MGH terminology and concepts are not yet well defined or used consistently. These variations can complicate comparisons across settings. There is, therefore, a need to develop consensus and standardize concepts and data points to support the development of a robust MGH evidence-base for governments, event planners, responders, and researchers. This project explored the views and sought consensus of international MGH experts on previously published concepts around MGH to inform the development of a transnational minimum data set (MDS) with an accompanying data dictionary (DD)...
August 2016: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/27159897/imaging-mass-spectrometry-molecular-microscopy-for-the-new-age-of-biology-and-medicine
#17
Richard M Caprioli
Imaging mass spectrometry provides a powerful tool for monitoring and discovery of molecular processes in the spatial domain in tissues for research and practical applications in both biology and medicine. This technology directly measures molecular compounds in tissues without the use of target-specific reagents such as antibodies, is applicable to a wide variety of analytes, and can provide spatial resolutions below the single cell level. Importantly, it has paradigm shifting capabilities in clinical applications, especially for anatomic pathology...
June 2016: Proteomics
https://www.readbyqxmd.com/read/27013749/setting-up-and-functioning-of-an-emergency-medicine-department-lessons-learned-from-a-preliminary-study
#18
K Asish, Varun Suresh
BACKGROUND AND AIMS: Tertiary care teaching hospitals remain referral centres for victims of trauma and mass casualty. Often specialists from various disciplines manage these crowded casualty areas. These age old casualty areas are being replaced, throughout the country by Emergency Medicine Departments (EMDs), presumed to be better planned to confront a crisis. We aimed to gather basic data contributive in setting up of an EMD at a tertiary care teaching hospital from the lessons learned from functioning existent systems...
February 2016: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/26917443/relevance-of-radiobiological-concepts-in-radionuclide-therapy-of-cancer
#19
REVIEW
Chandan Kumar, Neena Shetake, Sejal Desai, Amit Kumar, Grace Samuel, Badri N Pandey
PURPOSE: Radionuclide therapy (RNT) is a rapidly growing area of clinical nuclear medicine, wherein radionuclides are employed to deliver cytotoxic dose of radiation to the diseased cells/tissues. During RNT, radionuclides are either directly administered or delivered through biomolecules targeting the diseased site. RNT has been clinically used for diverse range of diseases including cancer, which is the focus of the review. CONCLUSIONS: The major emphasis in RNT has so far been given towards developing peptides/antibodies and other molecules to conjugate a variety of therapeutic radioisotopes for improved targeting/delivery of radiation dose to the tumor cells...
2016: International Journal of Radiation Biology
https://www.readbyqxmd.com/read/26873277/tuberculosis-and-mass-gatherings-opportunities-for-defining-burden-transmission-risk-and-the-optimal-surveillance-prevention-and-control-measures-at-the-annual-hajj-pilgrimage
#20
Alimuddin Zumla, Abdulaziz Bin Saeed, Badriah Alotaibi, Saber Yezli, Osman Dar, Kingsley Bieh, Matthew Bates, Tamara Tayeb, Peter Mwaba, Shuja Shafi, Brian McCloskey, Eskild Petersen, Esam I Azhar
Tuberculosis (TB) is now the most common infectious cause of death worldwide. In 2014, an estimated 9.6 million people developed active TB. There were an estimated three million people with active TB including 360000 with multidrug-resistant TB (MDR-TB) who were not diagnosed, and such people continue to fuel TB transmission in the community. Accurate data on the actual burden of TB and the transmission risk associated with mass gatherings are scarce and unreliable due to the small numbers studied and methodological issues...
June 2016: International Journal of Infectious Diseases: IJID
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