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https://www.readbyqxmd.com/read/28651406/-survival-time-of-newly-diagnosed-hiv-aids-cases-and-related-factors-in-china-2010
#1
H L Tang, J Li, J Han, J Xu, Y R Mao
Objective: To analyze the survival time of newly diagnosed HIV/AIDS cases and related factors in China in 2010. Methods: The reporting cards and follow-up cards of HIV/AIDS cases reported as of 31 December 2015 were collected from national AIDS information system. The newly diagnosed HIV/AIDS cases in 2010 were selected. The information of follow-up intervention, CD(4+)T cells (CD(4)) testing, antiretroviral treatment and mortality of the cases from 2010 to 2015 were analyzed. Life table method was applied to calculate the survival probability...
May 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28651348/an-e-e-ratio-on-echocardiography-predicts-the-existence-of-left-atrial-low-voltage-areas-and-poor-outcomes-after-catheter-ablation-for-atrial-fibrillation
#2
Masaharu Masuda, Masashi Fujita, Osamu Iida, Shin Okamoto, Takayuki Ishihara, Kiyonori Nanto, Takashi Kanda, Akihiro Sunaga, Takuya Tsujimura, Yasuhiro Matsuda, Takuya Ohashi, Masaaki Uematsu
Aims: An elevated left atrial pressure has been reported to play an important role in the development of atrial remodelling in atrial fibrillation (AF) patients. The study aimed at elucidating the association between the diastolic early transmitral flow velocity/mitral annular velocity (E/e', a non-invasive surrogate of left atrial pressure) and left atrial low-voltage-area existence, and the prognostic impact of the E/e' on procedural outcomes in patients undergoing AF ablation. Methods and results: Total of 215 consecutive patients were divided into 3 groups based on the estimated left atrial pressure: normal (E/e' < 8...
June 22, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28651307/role-of-shear-wave-elastography-in-evaluating-the-risk-of-hepatocellular-carcinoma-in-patients-with-chronic-hepatitis-b
#3
Jae Yoon Jeong, Joo Hyun Sohn, Won Sohn, Chan Hyuk Park, Tae Yeob Kim, Dae Won Jun, Yongsoo Kim, Woo Kyoung Jeong
Background/Aims: To investigate the use of measurements of liver stiffness (LS) by two-dimensional real-time shear wave elastography (SWE) for predicting the development of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB). Methods: We retrospectively collected data on 291 enrolled patients with CHB whose LS had been measured using SWE. Results: The mean age of the patients was 46.8 years; males predominated (67%), and 40 of the patients (14%) had clinical cirrhosis...
June 27, 2017: Gut and Liver
https://www.readbyqxmd.com/read/28651186/circulating-malondialdehyde-modified-low-density-lipoprotein-mda-ldl-as-a-novel-predictor-of-clinical-outcome-after-endovascular-therapy-in-patients-with-peripheral-artery-disease-pad
#4
Taka-Aki Takamura, Taketsugu Tsuchiya, Minako Oda, Makoto Watanabe, Ryuhei Saito, Ryoko Sato-Ishida, Hironobu Akao, Yasuyuki Kawai, Michihiko Kitayama, Kouji Kajinami
BACKGROUND AND AIMS: Despite advances in the treatment of peripheral artery disease (PAD), cardiovascular events and death rates remain high. This study aimed at identifying markers of outcome in patients with PAD undergoing endovascular therapy (EVT). METHODS: Consecutive patients undergoing EVT were recruited. Markers of oxidative stress (malondialdehyde-modified low-density lipoprotein [MDA-LDL]), inflammation (IL-6; high-sensitivity C-reactive protein [hsCRP]) and fibrinolysis (D-dimer) were measured pre-EVT and at post-EVT time-points to 36 h...
June 16, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28651179/sedentary-work-and-the-risks-of-colon-and-rectal-cancer-by-anatomical-sub-site-in-the-canadian-census-health-and-environment-cohort-canchec
#5
Manisha Pahwa, M Anne Harris, Jill MacLeod, Michael Tjepkema, Paul A Peters, Paul A Demers
BACKGROUND: Sedentary behaviour is a potential risk factor for colorectal cancer. We examined the association between sedentary work, based on body position, and colorectal cancer risk in Canadians. METHODS: A working body position category (a. sitting; b. standing and walking; c. sitting, standing, and walking; d. other) was assigned to occupations reported by 1991 Canadian Census respondents based on national occupational counselling guidelines. Adjusted hazard ratios (HRs) and 95% confidence intervals (CI) were estimated for cancers of the colon (overall, proximal, and distal) and rectum in men and women newly diagnosed from 1992 to 2010...
June 23, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28651160/significance-of-extranodal-tumour-deposits-in-colorectal-cancer-a-systematic-review-and-meta-analysis
#6
REVIEW
Amy C Lord, Nigel D'Souza, Philip H Pucher, Brendan J Moran, A Muti Abulafi, Andrew Wotherspoon, Shahnawaz Rasheed, Gina Brown
AIMS: The presence and significance of extranodal tumour deposits (ENTDs) in colorectal cancer (CRC) continue to cause controversy in terms of origin, classification and prognostic significance. This review aims to assess current evidence on the origin of ENTDs in CRC and their effect on overall and disease-free survival. METHODS: A systematic review and meta-analysis were carried out in accordance with the Preferred Reporting Items for Systematic reviews and Meta-analyses (PRISMA) guidelines...
June 23, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28651012/the-economic-burden-of-human-papillomavirus-related-precancers-and-cancers-in-sweden
#7
Ellinor Östensson, Maria Silfverschiöld, Lennart Greiff, Christine Asciutto, Johan Wennerberg, Marie-Louise Lydryp, Ulf Håkansson, Pär Sparén, Christer Borgfeldt
BACKGROUND: High-risk (HR) human papillomavirus (HPV) infection is an established cause of malignant disease. We used a societal perspective to estimate the cost of HR HPV-related cervical, vulvar, vaginal, anal, and penile precancer and cancer, and oropharyngeal cancer in Sweden in 2006, 1 year before HPV vaccination became available in the country. MATERIALS AND METHODS: This prevalence-based cost-of-illness study used diagnosis-specific data from national registries to determine the number of HR HPV-related precancers and cancers...
2017: PloS One
https://www.readbyqxmd.com/read/28651011/indications-of-airway-stenting-for-severe-central-airway-obstruction-due-to-advanced-cancer
#8
Hiroaki Nagano, Tomoo Kishaba, Yuichirou Nei, Shin Yamashiro, Hiroaki Takara
BACKGROUND: Management of severe central airway obstruction due to advanced cancer is a medical and technical challenge. The impact of airway stenting on the clinical outcome of such patients is unclear. METHOD: This single-center, retrospective study evaluated 21 patients who underwent airway stenting for advanced cancer. We examined predictors of the post-stenting mortality, including age, serum albumin, tracheal diameter, smoking, opioid use, respiratory failure, and performance status (PS)...
2017: PloS One
https://www.readbyqxmd.com/read/28650984/clinical-characteristics-of-second-primary-pancreatic-cancer
#9
Jung Hyun Jo, In Rae Cho, Jang Han Jung, Hee Seung Lee, Moon Jae Chung, Seungmin Bang, Seung Woo Park, Jae Bock Chung, Si Young Song, Jeong Youp Park
PURPOSE: Several studies reported the increased risk of second primary pancreatic ductal adenocarcinoma (2nd PDAC) in cancer survivors. However, data on the characteristics of 2nd PDAC are insufficient. METHODS: This retrospective cohort study included 1759 patients with PDAC. They were classified as having 2nd PDAC or first primary PDAC (1st PDAC) according to a prior diagnosed cancer of different origin, at least 6 months before PDAC diagnosis. RESULTS: There were 110 patients (6...
2017: PloS One
https://www.readbyqxmd.com/read/28650972/contribution-of-cognitive-performance-and-cognitive-decline-to-associations-between-socioeconomic-factors-and-dementia-a-cohort-study
#10
Jennifer Rusmaully, Aline Dugravot, Jean-Paul Moatti, Michael G Marmot, Alexis Elbaz, Mika Kivimaki, Séverine Sabia, Archana Singh-Manoux
BACKGROUND: Socioeconomic disadvantage is a risk factor for dementia, but longitudinal studies suggest that it does not affect the rate of cognitive decline. Our objective is to understand the manner in which socioeconomic disadvantage shapes dementia risk by examining its associations with midlife cognitive performance and cognitive decline from midlife to old age, including cognitive decline trajectories in those with dementia. METHODS AND FINDINGS: Data are drawn from the Whitehall II study (N = 10,308 at study recruitment in 1985), with cognitive function assessed at 4 waves (1997, 2002, 2007, and 2012)...
June 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28650577/time-dependent-trends-in-cardiovascular-adverse-events-during-follow-up-after-carotid-or-iliofemoral-endarterectomy
#11
I D van Koeverden, S T W van Haelst, S Haitjema, J-P P M de Vries, F L Moll, H M den Ruijter, I E Hoefer, G W Dalmeijer, G J de Borst, G Pasterkamp
BACKGROUND: Recent observations have suggested a decline in vulnerable carotid artery and iliofemoral atherosclerotic plaque characteristics over the past decade. The aim of this study was to determine whether, in the presence of clinically manifest carotid or peripheral artery disease, secondary adverse cardiovascular events decreased over this period. METHODS: Patients included in the Athero-Express biobank between 2003 and 2012 were analysed. During 3-year follow-up, composite cardiovascular endpoints were documented yearly, including: myocardial infarction, coronary interventions, stroke, peripheral interventions and cardiovascular death...
June 26, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28650564/the-impact-of-extrahepatic-disease-among-patients-undergoing-liver-directed-therapy-for-neuroendocrine-liver-metastasis
#12
Aslam Ejaz, Brad N Reames, Shishir Maithel, George A Poultsides, Todd W Bauer, Ryan C Fields, Matt Weiss, Hugo Pinto Marques, Luca Aldrighetti, Timothy M Pawlik
INTRODUCTION: Management of neuroendocrine liver metastasis (NELM) in the presence of extrahepatic disease (EHD) is controversial. We sought to examine outcomes of patients undergoing liver-directed therapy (resection, ablation, or both) for NELM in the presence of EHD using a large international cohort of patients. METHODS: 612 patients who underwent liver-directed therapy were identified from eight institutions. Postoperative outcomes, as well as and overall (OS) were compared among patients with and without EHD...
June 26, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28650513/return-to-work-after-work-related-stress-a-randomized-controlled-trial-of-a-work-focused-cognitive-behavioral-intervention
#13
Vita Ligaya Dalgaard, Kirstin Aschbacher, Johan Hviid Andersen, David John Glasscock, Morten Vejs Willert, Ole Carstensen, Karin Biering
Objectives This study aimed to evaluate the effect of a stress management intervention (SMI) on lasting return to work (RTW) among patients with work-related stress complaints. Methods Sickness benefit departments from three local municipalities referred patients on sick leave with work-related adjustment disorders or mild depression to the Department of Occupational Medicine, Regional Hospital West Jutland. A 2× randomization procedure allocated patients into one of three groups: intervention (N=58), control A (which received a clinical assessment; N=56), or control B (no assessment; N=49)...
June 26, 2017: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/28650507/stabilisation-of-gold-nanoparticles-by-n-heterocyclic-thiones
#14
Leonardo C Moraes, Bertrand Lacroix, Rute C Figueiredo, Patricia Lara, Javier Rojo, Salvador Conejero
Gold nanoparticles (Au-NPs) have been prepared using N-heterocyclic thiones (NHTs) as ligand stabilisers. These Au-NPs have been shown to be very stable, even in air, and have been characterized by a combination of several techniques (TEM, HR-TEM, STEM-HAADF, EDX, DLS, elemental analysis and (1)H NMR). These nanoparticles are active in the catalytic reduction of nitroarenes to anilines.
June 26, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28650277/attenuated-post-exercise-heart-rate-recovery-in-patients-with-systemic-lupus-erythematosus-the-role-of-disease-severity-and-beta-blocker-treatment
#15
P Bienias, M Ciurzyński, A Chrzanowska, I Dudzik-Niewiadomska, K Irzyk, K Oleszek, A Kalińska-Bienias, B Kisiel, W Tłustochowicz, P Pruszczyk
Objective Sinus tachycardia is frequently reported in systemic lupus erythematosus (SLE), while there are limited data on post-exercise ability to slow heart rate (i.e. heart rate recovery, HRR) in this group of patients. Methods We studied consecutive 70 patients with SLE and 30 healthy controls. All examined individuals underwent detailed clinical examination, echocardiography, Holter monitoring with heart rate variability and treadmill stress test using Bruce's protocol. HRR values were calculated as the difference between maximum HR during exercise and HR at the first (HRR1) and third (HRR3) minute of rest...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28650184/effects-of-nicotine-versus-placebo-e-cigarette-use-on-symptom-relief-during-initial-tobacco-abstinence
#16
Kenneth A Perkins, Joshua L Karelitz, Valerie C Michael
Because electronic cigarettes (e-cigs) containing nicotine may relieve smoking abstinence symptoms similar to nicotine replacement therapy medication, we used within-subjects designs to test these effects with a first-generation e-cig in nonquitting and quitting smokers. In Study 1, 28 nontreatment-seeking smokers abstained overnight prior to each of 3 sessions. Minnesota Nicotine Withdrawal Scale (MNWS) withdrawal (and craving item) relief was assessed following 4 exposures (each 10 puffs) over 2 hr to e-cigs that either did (36 mg/ml) or did not (i...
June 26, 2017: Experimental and Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28650080/effects-of-central-administration-of-resistin-on-renal-sympathetic-nerve-activity-in-rats-fed-a-high-fat-diet-a-comparison-with-leptin
#17
Hamza Habeeballah, Naif Alsuhaymi, Martin J Stebbing, Emilio Badoer
Resistin acts centrally to increase renal sympathetic nerve activity (RSNA). This is similar to leptin. In high fat fed animals, the sympatho-excitatory effects of leptin are retained, in contrast to the reduced actions of leptin on dietary intake. In the present study we investigated whether the sympatho-excitatory actions of resistin were influenced by a high fat diet. Further, since resistin and leptin combined can induce a greater sympatho-excitatory response than each alone in rats fed a normal chow diet, we investigated whether a high fat diet (22%) could influence this centrally mediated interaction...
June 26, 2017: Journal of Neuroendocrinology
https://www.readbyqxmd.com/read/28650033/chloride-assisted-supramolecular-assembly-of-a-luminescent-gigantic-cluster-ag216s56cl7-c-triple-bond-length-as-m-dash-cph-98-h2o-12-with-pseudo-th-skeleton-and-five-shell-arrangement
#18
Zi-Yi Chen, Dennis Y S Tam, Thomas C W Mak
Using a chloride-assisted supramolecular building-block approach, we have employed the molecular Cl@Agm(C[triple bond, length as m-dash]CPh)n entity in the construction of a gigantic cluster namely [Ag216S56Cl7(C[triple bond, length as m-dash]CPh)98(H2O)12][Ag3(imidazole)(H2O)4](SbF6)2 (1), which contains the largest discrete organometallic cluster investigated by X-ray crystallography. Based on an icosahedral Cl@Ag12 kernel, this spheroidal cluster features an unprecedented five-shell structure Cl@Ag12@S12@Ag32@S44Cl6@Ag172 with idealized Th symmetry...
June 26, 2017: Nanoscale
https://www.readbyqxmd.com/read/28649974/utility-of-sup-13-sup-c-methacetin-breath-test-in-predicting-long-term-survival-of-patients-with-decompensated-cirrhosis
#19
Segundo Moran, Aline Mina, Ximena Duque, Nayeli Ortiz-Olvera, Gustavo Rodríguez-Leal, Jose Sierra-Ramirez, Roberto Medina, Robertino Mera, Misael Uribe
The 13C-methacetin breath test (13C-MeBT) is a noninvasive tool that allows evaluation of the functional activity of the liver and the prediction of liver cirrhosis. Nevertheless, there is no information on its potential utility to predict long-term survival in patients with liver disease. Methods: Patients with cirrhosis were selected. All patients underwent a complete clinical assessment, standard biochemical tests, and 13C-MeBT at the beginning of the study. Death was recorded during the three years of follow-up...
June 26, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28649938/epidemiology-and-survival-of-cervical-cancer-in-the-french-west-indies-data-from-the-martinique-cancer-registry-2002-2011
#20
K Melan, E Janky, J Macni, S Ulric-Gervaise, M-J Dorival, J Veronique-Baudin, C Joachim
BACKGROUND: The Caribbean ranks seventh among world regions most affected by cervical cancer. Social health inequalities, such as differences in access to screening services, engender disparities in incidence and mortality between low- and middle-income countries and industrialized countries. The French National Cancer Plan 2014-2019 focuses on reducing inequalities in cervical cancer. OBJECTIVE: The aim of this study was to describe the geographical distribution and overall survival of cervical cancer, based on data from a population-based cancer registry in Martinique (French West-Indies)...
2017: Global Health Action
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