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Dindo-Clavien

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https://www.readbyqxmd.com/read/27897432/low-skeletal-muscle-radiation-attenuation-and-visceral-adiposity-are-associated-with-overall-survival-and-surgical-site-infections-in-patients-with-pancreatic-cancer
#1
David P J van Dijk, Maikel J A M Bakens, Mariëlle M E Coolsen, Sander S Rensen, Ronald M van Dam, Martijn J L Bours, Matty P Weijenberg, Cornelis H C Dejong, Steven W M Olde Damink
BACKGROUND: Cancer cachexia and skeletal muscle wasting are related to poor survival. In this study, quantitative body composition measurements using computed tomography (CT) were investigated in relation to survival, post-operative complications, and surgical site infections in surgical patients with cancer of the head of the pancreas. METHODS: A prospective cohort of 199 patients with cancer of the head of the pancreas was analysed by CT imaging at the L3 level to determine (i) muscle radiation attenuation (average Hounsfield units of total L3 skeletal muscle); (ii) visceral adipose tissue area; (iii) subcutaneous adipose tissue area; (iv) intermuscular adipose tissue area; and (v) skeletal muscle area...
October 26, 2016: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/27834023/laparoscopic-adrenalectomy-by-transabdominal-lateral-approach-20%C3%A2-years-of-experience
#2
Thibaut Coste, Robert Caiazzo, Fanelly Torres, Marie Christine Vantyghem, Bruno Carnaille, François Pattou, Christine Do Cao, Claire Douillard
BACKGROUND: Laparoscopic adrenalectomy (LA) has become the standard technique for most indications. The aim of this study was to determine the predictive factors of intra- and postoperative complications in order to inform the orientation of patient to a surgeon with more experience in adrenal surgery. METHODS: From January 1994 to December 2013, 520 consecutive patients benefited from LA at Huriez Hospital, Lille, France. Each complication was graded according to the Dindo-Clavien-grade scale...
November 10, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27816312/transition-from-open-to-laparoscopic-alpps-for-patients-with-very-small-flr-the-initial-experience
#3
Marcel A C Machado, Fábio F Makdissi, Rodrigo C Surjan, Tiago Basseres, Erik Schadde
BACKGROUND: Laparoscopic ALPPS (Associating Liver Partition and Portal vein ligation for Staged hepatectomy) has been reported in individual reports, but has been the authors' default option since 2015. METHODS: A retrospective analysis of all consecutive patients undergoing ALPPS at a single referral center was performed using a prospective database from July 2011 to June 2016. Feasibility was studied by assessing conversions. The 90-day mortality and complications were analyzed using a Dindo-Clavien score and the comprehensive complication index...
November 2, 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/27812143/perioperative-non-invasive-indocyanine-green-clearance-testing-to-predict-postoperative-outcome-after-liver-resection
#4
Stefanie Haegele, Silvia Reiter, David Wanek, Florian Offensperger, David Pereyra, Stefan Stremitzer, Edith Fleischmann, Christine Brostjan, Thomas Gruenberger, Patrick Starlinger
BACKGROUND: Postoperative liver dysfunction may lead to morbidity and mortality after liver resection. Preoperative liver function assessment is critical to identify preexisting liver dysfunction in patients prior to resection. The aim of this study was to evaluate the predictive potential of perioperative indocyanine green (ICG)-clearance testing to prevent postoperative liver dysfunction and morbidity using standardized outcome parameters in a routine Western-clinical-setting. STUDY DESIGN: 137 patients undergoing partial hepatectomy between 2011 and 2013, at the general hospital of Vienna, were included...
2016: PloS One
https://www.readbyqxmd.com/read/27726290/docetaxel-cisplatin-and-5-fluorouracil-as-perioperative-chemotherapy-compared-with-surgery-alone-for-resectable-gastroesophageal-adenocarcinoma
#5
Frédéric Fiteni, Sophie Paget-Bailly, Mathieu Messager, Thierry N'Guyen, Zaher Lakkis, Pierre Mathieu, Najib Lamfichekh, Alain Picard, Bilell Benzidane, Denis Cléau, Franck Bonnetain, Christophe Borg, Christophe Mariette, Stefano Kim
Docetaxel, cisplatin, and 5-fluorouracil (DCF) significantly improved overall survival in metastatic gastroesophageal adenocarcinoma (GEA). The aim of this study was to assess efficacy of DCF regimen as perioperative chemotherapy compared with surgery alone in patients with resectable GEA. We identified 789 patients who underwent surgery alone and 62 patients who received at least one cycle of DCF regimen consisting of docetaxel (75 mg/m(2) on day 1), cisplatin (75 mg/m(2) on day 1), and 5-fluorouracil (750 mg/m(2) /day on continuous perfusion on days 1 to 5), every 3 weeks...
November 2016: Cancer Medicine
https://www.readbyqxmd.com/read/27716240/salvage-surgery-for-local-failures-after-stereotactic-ablative-radiotherapy-for-early-stage-non-small-cell-lung-cancer
#6
Naomi E Verstegen, Alexander P W M Maat, Frank J Lagerwaard, Marinus A Paul, Michel I Versteegh, Joris J Joosten, Willem Lastdrager, Egbert F Smit, Ben J Slotman, Joost J M E Nuyttens, Suresh Senan
INTRODUCTION: The literature on surgical salvage, i.e. lung resections in patients who develop a local recurrence following stereotactic ablative radiotherapy (SABR), is limited. We describe our experience with salvage surgery in nine patients who developed a local recurrence following SABR for early stage non-small cell lung cancer (NSCLC). METHODS: Patients who underwent surgical salvage for a local recurrence following SABR for NSCLC were identified from two Dutch institutional databases...
October 3, 2016: Radiation Oncology
https://www.readbyqxmd.com/read/27708521/laparoscopic-versus-open-liver-resection-for-hepatocellular-carcinoma-initial-experience-in-greece
#7
Georgios C Sotiropoulos, Nikolaos Machairas, Paraskevas Stamopoulos, Ioannis D Kostakis, Dimitrios Dimitroulis, Dimitrios Mantas, Gregory Kouraklis
BACKGROUND: Liver resection represents the treatment of choice for a small proportion of patients with hepatocellular carcinoma (HCC), amenable to surgery. The remarkable evolution in surgical techniques during the last decades introduced laparoscopic hepatectomy in the operative management of HCC, even in the presence of liver cirrhosis. No comparative study on laparoscopic or open liver resection for HCC has been conducted in Greece yet. METHODS: Patients undergoing liver resection for HCC by one senior hepatobiliary surgeon in our Institution during the period 11/2011-02/2016 were prospectively sampled and retrospectively analyzed for the purposes of this study...
October 2016: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/27650993/iatrogenic-hip-instability-is-a-devastating-complication-after-the-modified-dunn-procedure-for-severe-slipped-capital-femoral-epiphysis
#8
Vidyadhar V Upasani, Oliver Birke, Kevin E Klingele, Michael B Millis
BACKGROUND: The modified Dunn procedure facilitates femoral capital realignment for slipped capital femoral epiphysis (SCFE) through a surgical hip dislocation approach. Iatrogenic postoperative hip instability after this procedure has not been studied previously; however, we were concerned when we observed several instances of this serious complication, and we wished to study it further. QUESTIONS/PURPOSES: The purpose of this study was to evaluate the frequency, timing, and clinical presentation (including complications) associated with iatrogenic instability after the modified Dunn procedure for SCFE...
September 20, 2016: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/27646023/surgical-treatment-of-colorectal-cancer-with-peritoneal-and-liver-metastases-using-combined-liver-and-cytoreductive-surgery-and-hyperthermic-intraperitoneal-chemotherapy-report-from-a-single-centre-experience
#9
Julie Navez, Christophe Remue, Daniel Leonard, Radu Bachmann, Alex Kartheuser, Catherine Hubert, Laurent Coubeau, Mina Komuta, Marc Van den Eynde, Francis Zech, Nicolas Jabbour
BACKGROUND: Chemotherapeutic advances have enabled successful cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) expansion in treating metastatic colorectal cancer. OBJECTIVES: The aims of this study were to evaluate the safety of combining liver surgery (LS) with HIPEC and CRS (which remains controversial) and its impact on overall survival (OS) rates. METHODS: From 2007 to 2015, a total of 77 patients underwent CRS/HIPEC for peritoneal carcinomatosis (PC) of colorectal cancer...
September 19, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27629502/multicentre-study-of-the-impact-of-morbidity-on-long-term-survival-following-hepatectomy-for-intrahepatic-cholangiocarcinoma
#10
A Doussot, C Lim, C Gómez Gavara, D Fuks, O Farges, J M Regimbeau, D Azoulay
BACKGROUND: The impact of morbidity on long-term outcomes following liver resection for intrahepatic cholangiocarcinoma is currently unclear. METHODS: This was a retrospective analysis of all consecutive patients who underwent liver resection for intrahepatic cholangiocarcinoma with curative intent in 24 university hospitals between 1989 and 2009. Severe morbidity was defined as any complication of Dindo-Clavien grade III or IV. Patients with severe morbidity were compared with those without in terms of demographics, pathology, management, morbidity, overall survival, disease-free survival and time to recurrence...
December 2016: British Journal of Surgery
https://www.readbyqxmd.com/read/27593596/parenchymal-sparing-hepatectomies-psh-for-bilobar-colorectal-liver-metastases-are-associated-with-a-lower-morbidity-and-similar-oncological-results-a-propensity-score-matching-analysis
#11
Riccardo Memeo, Vito de Blasi, René Adam, Diane Goéré, Daniel Azoulay, Ahmet Ayav, Emilie Gregoire, Reza Kianmanesh, Francis Navarro, Antonio Sa Cunha, Patrick Pessaux
OBJECTIVE: The aim of this study is to evaluate whether a parenchymal-sparing strategy provides similar results in terms of morbidity, mortality, and oncological outcome of non-PSH hepatectomies in a propensity score matched population (PSMP) in case of multiple (>3) bilobar colorectal liver metastases (CLM). BACKGROUND: The surgical treatment of bilobar liver metastasis is challenging due to the necessity to achieve complete resection margins and a sufficient future remnant liver...
September 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/27565062/long-term-outcomes-of-sandwich-ventral-hernia-repair-paired-with-hybrid-vacuum-assisted-closure
#12
Caitlin W Hicks, Katherine E Poruk, Pablo A Baltodano, Kevin C Soares, Said C Azoury, Carisa M Cooney, Peter Cornell, Frederic E Eckhauser
BACKGROUND: Sandwich ventral hernia repair (SVHR) may reduce ventral hernia recurrence rates, although with an increased risk of surgical site occurrences (SSOs) and surgical site infections (SSIs). Previously, we found that a modified negative pressure wound therapy (hybrid vacuum-assisted closure [HVAC]) system reduced SSOs and SSIs after ventral hernia repair. We aimed to describe our outcomes after SVHR paired with HVAC closure. METHODS: We conducted a 4-y retrospective review of all complex SVHRs (biologic mesh underlay and synthetic mesh overlay) with HVAC closure performed at our institution by a single surgeon...
August 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27545327/a-donor-body-mass-index-greater-than-30-is-not-a-contraindication-for-live-liver-donation
#13
M Knaak, N Goldaracena, A Doyle, M S Cattral, P D Greig, L Lilly, I D McGilvray, G A Levy, A Ghanekar, E L Renner, D R Grant, M Selzner, N Selzner
The increased prevalence of obesity worldwide threatens the pool of living liver donors. While the negative effects of graft steatosis on liver donation and transplantation is well known, the impact of obesity in the absence of hepatic steatosis on outcome of living donor liver transplantation (LDLT) is unknown. Therefore, we compared the outcome of LDLT using donors with a BMI<30kg/m(2) vs donors with a BMI ≥30kg/m(2) . Between April 2000-May 2014, 105 patients received a right lobe liver graft from donors with BMI ≥30kg/m(2) , while 364 recipients were transplanted with grafts from donors with BMI<30kg/m(2) ...
August 22, 2016: American Journal of Transplantation
https://www.readbyqxmd.com/read/27496470/usefulness-of-modified-dindo-clavien-scale-to-evaluate-the-correlation-between-the-severity-of-surgical-complications-and-complications-related-to-the-renal-and-pancreatic-grafts-after-simultaneous-kidney-and-pancreas-transplantation
#14
T Grochowiecki, K Madej, Z Gałązka, T Jakimowicz, M Jędrasik, P Świercz, K Łukawski, L Pączek, M Durlik, S Nazarewski, J Szmidt
OBJECTIVE: Simultaneous pancreas and kidney transplantation (spktx) is the multiorgan transplantation. Thus various complications originated from transplanted organs and the complications that are not directly related to pancreatic or renal grafts could be developed at the same recipient. AIM: The aim of this study is to explore whether there is a correlation between the severity of complications originated from transplanted pancreas, transplanted kidney and general surgical complication developed at the same spktx recipient...
June 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27438422/is-resection-of-hepatocellular-carcinoma-in-the-era-of-liver-transplantation-worthwile-a-single-center-experience
#15
Paulo Herman, Felipe de Lucena Moreira Lopes, Jaime Arthur Pirola Kruger, Gilton Marques Fonseca, Vagner Birk Jeismann, Fabricio Ferreira Coelho
BACKGROUND: - Liver resection for hepatocellular carcinoma is a potentially curative therapeutic procedure that can be performed readily after its indication, without the need of a long waiting time and lower costs when compared to liver transplantation, being a good alternative in patients with preserved/good liver function. OBJECTIVE: - Evaluate long-term results of liver resection from a high volume single center for selected patients with hepatocellular carcinoma in a context of a long waiting list for liver transplant...
July 2016: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/27339754/normothermic-ex-vivo-liver-perfusion-using-steen-solution-as-perfusate-for-human-liver-transplantation-first-north-american-results
#16
Markus Selzner, Nicolas Goldaracena, Juan Echeverri, Johan M Kaths, Ivan Linares, Nazia Selzner, Cyril Serrick, Max Marquez, Gonzalo Sapisochin, Eberhard L Renner, Mamatha Bhat, Ian D McGilvray, Leslie Lilly, Paul D Greig, Cynthia Tsien, Mark S Cattral, Anand Ghanekar, David R Grant
The European trial investigating normothermic ex vivo liver perfusion (NEVLP) as a preservation technique for liver transplantation (LT) uses gelofusine, a non-US Food and Drug Administration-approved, bovine-derived, gelatin-based perfusion solution. We report a safety and feasibility clinical NEVLP trial with human albumin-based Steen solution. Transplant outcomes of 10 human liver grafts that were perfused on the Metra device at 37 °C with Steen solution, plus 3 units of erythrocytes were compared with a matched historical control group of 30 grafts using cold storage (CS) as the preservation technique...
November 2016: Liver Transplantation
https://www.readbyqxmd.com/read/27323658/reporting-adverse-events-in-cancer-surgery-randomized-trials-a-systematic-review-of-published-trials-in-oesophago-gastric-and-gynecological-cancer-patients
#17
REVIEW
Leila Meghelli, Fabrice Narducci, Christophe Mariette, Guillaume Piessen, Marie Vanseymortier, Eric Leblanc, Pierre Collinet, Alain Duhamel, Nicolas Penel
BACKGROUND: Few reports describe how adverse events (AEs) are reported in cancer surgery trials. MATERIALS AND METHODS: We systematically reviewed 179 consecutive study reports issued between January 1, 1990 and November 15, 2014, which investigated surgery in oesophago-gastric (OG) or gynecologic (GY) cancer patients. Based on the reviewed reports, we assessed how AEs were reported according to CONSORT statement. RESULTS: Morbidity assessment was the primary objective of 56 studies (31...
August 2016: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/27188297/value-of-percutaneous-radiologic-gastrostomy-for-patients-with-advanced-esophageal-cancer
#18
Keitaro Sofue, Yoshito Takeuchi, Masakatsu Tsurusaki, Kentaro Shibamoto, Noriaki Sakamoto, Kazuhiro Kitajima, Miyuki Sone, Kazuro Sugimura, Yasuaki Arai
BACKGROUND: Nutritional management is important throughout the treatment period for esophageal cancer patients. This study aimed to evaluate the feasibility of percutaneous radiologic gastrostomy (PRG) and to investigate whether PRG can be applied for patients with advanced esophageal cancer. METHODS: In this study, 89 patients (74 men and 15 women) with advanced esophageal cancer underwent PRG using computed tomography and fluoroscopic guidance. These patients were unsuitable candidates for endoscopic intervention because of esophageal stricture...
October 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27149307/laparoscopic-distal-pancreatectomy-learning-curve-and-experience-in-a-tertiary-center
#19
Ido Nachmany, Niv Pencovich, Amir Ben-Yehuda, Guy Lahat, Richard Nakache, Yaacov Goykhman, Nir Lubezky, Joseph M Klausner
BACKGROUND: Although laparoscopic distal pancreatectomy (LDP) is gradually recognized as a safe and effective alternative to open distal pancreatectomy (ODP), it is not yet widely accepted. OBJECTIVE: We describe our experience, with emphasis on the learning curve of LDP. METHODS: Patients who underwent distal pancreatectomy (DP) between January 2011 and August 2014 were included. Operative and postoperative parameters, as well as pathology reports were evaluated...
June 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/27148397/emergency-right-colectomy-which-strategy-when-primary-anastomosis-is-not-feasible
#20
Hugo Teixeira Farinha, Emmanuel Melloul, Dieter Hahnloser, Nicolas Demartines, Martin Hübner
BACKGROUND: Primary anastomosis is considered the standard strategy after right emergency colectomy. The present study aimed to evaluate alternative treatment strategies when primary anastomosis is not possible to prevent definitive ostomy. METHODS: This retrospective study included all consecutive patients who underwent right emergency colectomy between July 2006 and June 2013. Demographics, surgical data, and postoperative outcomes were entered in an anonymized database...
2016: World Journal of Emergency Surgery: WJES
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