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https://www.readbyqxmd.com/read/28804235/management-of-varicose-veins-and-chronic-venous-insufficiency-in-a-comparative-registry-with-nine-venoactive-products-in-comparison-with-stockings
#1
G Belcaro, M Dugall, R Luzzi, M Corsi, A Ledda, A Ricci, L Pellegrini, M R Cesarone, M Hosoi, B M Errichi, U Cornelli, R Cotellese, G Agus, B Feragalli
The aim of this registry study was to compare products used to control symptoms of CVI. Endpoints of the study were microcirculation, effects on volume changes, and symptoms (analogue scale). Pycnogenol, venoruton, troxerutin, the complex diosmin-hesperidin, Antistax, Mirtoselect (bilberry), escin, and the combination Venoruton-Pycnogenol (VE-PY) were compared with compressions. No safety or tolerability problems were observed. At inclusion, measurements in the groups were comparable: 1,051 patients completed the registry...
September 2017: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/28802027/performance-evaluation-of-the-bioneer-accupower%C3%A2-hiv-1-quantitative-rt-pcr-kit-comparison-with-the-roche-cobas%C3%A2-ampliprep-cobas-taqman%C3%A2-hiv-1-test-ver-2-0-for-quantification-of-hiv-1-viral-load-in-indonesia
#2
Agus Susanto Kosasih, Christine Sugiarto, Hubertus Hosti Hayuanta, Runingsih Juhaendi, Lyana Setiawan
BACKGROUND: Measurement of viral load in human immunodeficiency virus type 1 (HIV-1) infected patients is essential for the establishment of a therapeutic strategy. Several assays based on qPCR are available for the measurement of viral load; they differ in sample volume, technology applied, target gene, sensitivity and dynamic range. The Bioneer AccuPower® HIV-1 Quantitative RT-PCR is a novel commercial kit that has not been evaluated for its performance. OBJECTIVE: This study aimed to evaluate the performance of the Bioneer AccuPower® HIV-1 Quantitative RT-PCR kit...
August 8, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28795022/the-potency-of-chicken-egg-yolk-immunoglobulin-igy-specific-as-immunotherapy-to-mycobacterium-tuberculosis-infection
#3
Sri Agus Sudjarwo, Koerniasari Eraiko, Giftania Wardani Sudjarwo, Koerniasari
The aim of this study was to characterize of chicken egg yolk immunoglobulins (IgYs) specific as immunotherapy to Mycobacterium tuberculosis complex (MTBC) infection. Lohmann laying hens were immunized intramuscularly with antigenic of MTBC. Egg yolk was separated from egg white, and IgY antibody was then purified by multiple polyethylene glycols 6000 extraction and ammonium sulfate purification steps. The IgY anti-MTBC concentration in egg yolk increased at 2 weeks and it reached a maximum at 4 weeks after immunization...
July 2017: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/28793221/temporal-variation-in-single-cell-power-law-rheology-spans-the-ensemble-variation-of-cell-population
#4
PingGen Cai, Ryosuke Takahashi, Kaori Kuribayashi-Shigetomi, Agus Subagyo, Kazuhisa Sueoka, John M Maloney, Krystyn J Van Vliet, Takaharu Okajima
Changes in the cytoskeletal organization within cells can be characterized by large spatial and temporal variations in rheological properties of the cell (e.g., the complex shear modulus G(∗)). Although the ensemble variation in G(∗) of single cells has been elucidated, the detailed temporal variation of G(∗) remains unknown. In this study, we investigated how the rheological properties of individual fibroblast cells change under a spatially confined environment in which the cell translational motion is highly restricted and the whole cell shape remains unchanged...
August 8, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28783478/three-dimensional-control-of-ion-channel-function-through-optogenetics-and-co-culture
#5
Viviana Agus, Paola Picardi, Loredana Redaelli, Lia Scarabottolo, Stefan Lohmer
The lack of miniaturized and cost-effective methods to control cellular excitability with dosable and temporally precise electrical perturbations represents a long-lasting and unsolved bottleneck for ion channel drug discovery pipelines. Here we developed a high-throughput-compatible fluorescent-based cellular assay that combines optogenetics and co-culture approaches to obtain spatial, temporal, and quantitative control of ion channel activity. The modularity and increased flexibility of control of this light-tandem assay, combined with contained costs and compatibility with conventional drug-screening platforms, make this system suitable for temporally precise screening of ion channel function in controlled conformations and can also be used to recapitulate other complexly regulated biological processes...
August 1, 2017: SLAS Discovery
https://www.readbyqxmd.com/read/28763720/increasing-the-uptake-of-long-acting-and-permanent-methods-of-family-planning-a-qualitative-study-with-village-midwives-in-east-java-and-nusa-tenggara-barat-provinces-indonesia
#6
Christiana R Titaley, Ratna U Wijayanti, Rita Damayanti, Agus Dwi Setiawan, Dadun, Dini Dachlia, Ferdinand Siagian, Heru Suparno, Dwi Astuti Yunita Saputri, Sarah Harlan, Yunita Wahyuningrum, Douglas Storey
OBJECTIVE: this analysis aims to explore midwives' insights into the provision of long-acting and permanent methods of contraception (LAPMs) in the selected areas of East Java and Nusa Tenggara Barat (NTB) Provinces, Indonesia. DESIGN: a qualitative study using in-depth interviews was conducted with 12 village midwives from 12 villages, to explore their perceptions and experiences in delivering family planning services. SETTING: the study was carried out in May-June 2013, as part of the baseline assessment in the Improving Contraceptive Method Mix (ICMM) study...
July 20, 2017: Midwifery
https://www.readbyqxmd.com/read/28758135/effect-of-chitosan-and-liposome-nanoparticles-as-adjuvant-codelivery-on-the-immunoglobulin-g-subclass-distribution-in-a-mouse-model
#7
Agus Haryono, Korrie Salsabila, Witta Kartika Restu, Sri Budi Harmami, Dodi Safari
BACKGROUND: We investigate the immunogenic properties of chitosan and liposome nanoparticles as adjuvant codelivery against a commercial pneumococcal conjugate vaccine (PCV) in an animal model. METHODS: The chitosan and liposome nanoparticles were prepared by ionic gelation and dry methods, respectively. The PCV immunization was performed intradermally in the presence of adjuvants and booster injections which were given without an adjuvant. The Quil-A® was used as a control adjuvant...
2017: Journal of Immunology Research
https://www.readbyqxmd.com/read/28734658/kidney-transplantation-a-new-era-of%C3%A2-laparoscopic-living-donor-nephrectomy-in%C3%A2-indonesia
#8
Albertus Marcelino, Chaidir Arif Mochtar, Irfan Wahyudi, Agus Rizal Hamid
BACKGROUND: Since its introduction in 1995, laparoscopic living donor nephrectomy (LLDN) has been a standard procedure in many transplantation centers worldwide. In 2011, LLDN was performed for the first time in Indonesia and became a standard procedure at our institution. The aim of this study is to evaluate the first 250 cases of LLDN at our institution. METHODS: Retrospective analyses were conducted of the first 250 cases of LLDN. All operations were performed between November 2011 and July 2015 at Cipto Mangunkusumo Hospital, Jakarta...
July 19, 2017: Asian Journal of Surgery
https://www.readbyqxmd.com/read/28725622/authentication-of-piper-betle-l-folium-and-quantification-of-their-antifungal-activity
#9
I Made Agus Gelgel Wirasuta, I Gusti Ayu Made Srinadi, Ida Bagus Gede Dwidasmara, Ni Luh Putu Putri Ardiyanti, I Gusti Ayu Arya Trisnadewi, Ni Luh Putu Vidya Paramita
The TLC profiles of intra- and inter-day precision for Piper betle L. (PBL) folium methanol extract was studied for their peak marker recognition and identification. The Numerical chromatographic parameters (NCPs) of the peak markers, the hierarchical clustering analysis (HCA) and the principal component analysis (PCA) were applied to authenticate the PBL. folium extract from other Piper species folium extract and to ensure the antifungal activity quality of the PBL essential oil. The spotted extract was developed with the mobile phase of toluene: ethyl acetate; 93:7, (v/v)...
July 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/28722264/ultrastructure-changes-in-buffalo-bubalus-bubalis-oocytes-before-and-after-maturation-in%C3%A2-vitro-with-sericin
#10
Sri Gustina, Hasbi Hasbi, Ni Wayan Kurniani Karja, Mohamad Agus Setiadi, Iman Supriatna
The aim of this research was to identify the changes in the cytoplasmic ultrastructure of immature and matured oocytes in buffalo (Bubalus bubalis). Oocytes were matured in vitro in tissue culture medium-199 with and without sericin, and then analyzed by light and transmission electron microscopy. The experiment result showed that the nuclear maturation rate of buffalo oocytes was significantly higher in the presence of sericin (80.6%) than without sericin (68.1%) (P < 0.05). The immature oocytes were characterized by cortical granule clusters in the ooplasm and the absence of perivitelline space (PVS)...
July 19, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/28695337/development-of-pediatric-neurosurgical-service-at-dr-soetomo-hospital-surabaya-indonesia
#11
REVIEW
Wihasto Suryaningtyas, Muhammad Arifin, Agus Turchan, Abdul Hafid Bajamal
PURPOSE: This review traces the history of pediatric neurosurgery at Dr. Soetomo General Hospital (DSGH) and its role in advancing the field of pediatric neurosurgery. METHODS: The history, the founding fathers, and the next generations of the pediatric neurosurgery in DSGH were traced back from original sources and authors' life stories. RESULT: Pediatric neurosurgical service at DSGH has its own unique perspective being a pediatric service in general hospital setting...
July 10, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28674718/seroprevalence-of-toxoplasma-gondii-rubella-virus-and-cytomegalovirus-among-pregnant-women-and-the-importance-of-avidity-assays
#12
Mumtaz C Sirin, Neval Agus, Nisel Yilmaz, Arzu Bayram, Yeser K Derici, Pinar Samlioglu, Sevgi Y Hanci, Guliz Dogan
OBJECTIVES: To determine the seroprevalence of Toxoplasma gondii (T. gondii), Rubella virus, and Cytomegalovirus (CMV) among pregnant women in Izmir, Turkey. METHODS: Medical records of pregnant women attending Izmir Tepecik Training and Research Hospital, Izmir, Turkey between January 2014 and January 2016 were analyzed in this retrospective cross-sectional study. The 7513 T. gondii IgM/IgG results, 7189 Rubella IgM/IgG results, 906 CMV IgM/IgG results and 146 avidity test results were evaluated...
July 2017: Saudi Medical Journal
https://www.readbyqxmd.com/read/28634145/taeniasis-caused-by-taenia-saginata-in-gianyar-town-and-taenia-solium-in-karangasem-villages-of-bali-indonesia-2011-2016-how-to-detect-tapeworm-carriers-anamnesis-or-microscopy
#13
Kadek Swastika, Toni Wandra, Nyoman Sadra Dharmawan, I Made Sudarmaja, John Master Saragih, Luh Putu Eka Diarthini, Luh Ariwati, Putu Ayu Asri Damayanti, Dewa Ayu Agus Sri Laksemi, Nengah Kapti, Putu Sutisna, Tetsuya Yanagida, Akira Ito
From January 2011 until September 2016, screening of taeniasis carriers was carried out in a town in Gianyar District (Taenia saginata) and in villages which consisted of several Banjars (the smallest community units) on the eastern slope of Mt. Agung, Karangasem District (Taenia solium) in Bali, Indonesia. Fecal samples from all community members who chose to participate were examined microscopically for detection of taeniid eggs each person completedwith a questionnaire to determine if they had seen whitish, noodle-like proglottids (anamnesis) in their feces...
June 17, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28625387/design-and-rationale-for-the-influenza-vaccination-after-myocardial-infarction-iami-trial-a-registry-based-randomized-clinical-trial
#14
RANDOMIZED CONTROLLED TRIAL
Ole Fröbert, Matthias Götberg, Oskar Angerås, Lena Jonasson, David Erlinge, Thomas Engstrøm, Jonas Persson, Svend E Jensen, Elmir Omerovic, Stefan K James, Bo Lagerqvist, Johan Nilsson, Amra Kåregren, Rasmus Moer, Cao Yang, David B Agus, Andrejs Erglis, Lisette O Jensen, Lars Jakobsen, Evald H Christiansen, John Pernow
BACKGROUND: Registry studies and case-control studies have demonstrated that the risk of acute myocardial infarction (AMI) is increased following influenza infection. Small randomized trials, underpowered for clinical end points, indicate that future cardiovascular events can be reduced following influenza vaccination in patients with established cardiovascular disease. Influenza vaccination is recommended by international guidelines for patients with cardiovascular disease, but uptake is varying and vaccination is rarely prioritized during hospitalization for AMI...
July 2017: American Heart Journal
https://www.readbyqxmd.com/read/28601043/pediatric-intermediate-care-and-pediatric-intensive-care-units-picu-metrics-and-an-analysis-of-patients-that-use-both
#15
Andrew S Geneslaw, Haomiao Jia, Adam R Lucas, Michael S D Agus, Jeffrey D Edwards
PURPOSE: To examine how intermediate care units (IMCUs) are used in relation to pediatric intensive care units (PICUs), characterize PICU patients that utilize IMCUs, and estimate the impact of IMCUs on PICU metrics. MATERIALS & METHODS: Retrospective study of PICU patients discharged from 108 hospitals from 2009 to 2011. Patients admitted from or discharged to IMCUs were characterized. We explored the relationships between having an IMCU and several PICU metrics: physical length-of-stay (LOS), medical LOS, discharge wait time, admission severity of illness, unplanned PICU admissions from wards, and early PICU readmissions...
May 26, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28578200/the-effects-of-diatom-pore-size-on-the-structures-and-extensibilities-of-single-mucilage-molecules
#16
Immanuel Sanka, Eko Agus Suyono, Parvez Alam
Diatoms secrete extracellular polymeric substances (EPS), or mucilage, around the cell wall that may serve to aid in motility and form a discrete layer that may help maintain thicker layers of EPS that have a greater role in adhesion. Mucilage molecules adhere to the diatom frustules, which are biosilica skeletons that develop from the diatom cell walls. Here, molecular dynamics methods were used to determine the characteristics of mucilage molecules as a function of pore size; notably 1,4-α-D-galacturonic acid, 1,4-β-glucuronic acid and 1,4-β-D-mannuronic acid...
May 26, 2017: Carbohydrate Research
https://www.readbyqxmd.com/read/28575785/effect-of-season-of-birth-on-cord-blood-ige-and-ige-at-birth-a-systematic-review-and-meta-analysis
#17
REVIEW
Nugroho Harry Susanto, Don Vicendese, Agus Salim, Adrian J Lowe, Shyamali C Dharmage, Rachel Tham, Caroline Lodge, Frances Garden, Katie Allen, Cecilie Svanes, Joachim Heinrich, Michael J Abramson, Bircan Erbas
BACKGROUND: Elevated cord blood IgE is important on the pathway to allergic disease. The association between season of birth and infant cord blood IgE is not well-established. Study findings differ on which birth season is associated with higher cord blood IgE risk and its magnitude. We conducted a systematic review and meta-analysis of studies on season of birth and cord blood IgE. METHODS: We searched Medline, Web of Science, Scopus and ProQuest Health databases, and reviewed reference lists of articles that met the inclusion criteria...
August 2017: Environmental Research
https://www.readbyqxmd.com/read/28566434/jun-mediated-downregulation-of-egfr-signaling-is-associated-with-resistance-to-gefitinib-in-egfr-mutant-nsclc-cell-lines
#18
Kian Kani, Carolina Garri, Katrin Tiemann, Paymaneh D Malihi, Vasu Punj, Anthony L Nguyen, Janet Lee, Lindsey D Hughes, Ruth M Alvarez, Damien M Wood, Ah Young Joo, Jonathan E Katz, David B Agus, Parag Mallick
Mutations or deletions in exons 18-21 in the EGFR) are present in approximately 15% of tumors in patients with non-small cell lung cancer (NSCLC). They lead to activation of the EGFR kinase domain and sensitivity to molecularly targeted therapeutics aimed at this domain (gefitinib or erlotinib). These drugs have demonstrated objective clinical response in many of these patients; however, invariably, all patients acquire resistance. To examine the molecular origins of resistance, we derived a set of gefitinib-resistant cells by exposing lung adenocarcinoma cell line, HCC827, with an activating mutation in the EGFR tyrosine kinase domain, to increasing gefitinib concentrations...
August 2017: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/28560848/advanced-silicon-chemistry-in-australia-forming-strong-links-with-asia
#19
Stephen Clarke, Kim-Anh Thi Nguyen, Elda Markovic, Neil Trout, Milena Ginic-Markovic, Janis Matisons, Michael Owen, Daniel Graiver, Agus Hadi Santosa Wargadipura, Sudirman Habibie, Dwi Gustiono, Bok Ryul Yoo, Joe Mifsud
This paper details Australian commercial and academic silicon research. Areas of interest include silicon metal, polysiloxane polymers, copolymers, cyclics, emulsions, microemulsions, silanes, silane coupling agents, sol-gel chemistry and water-treatments, porous silicon, polysiloxane degradation, silicon hydrogel contact lenses, silanolate synthesis, siloxane interfacial polymerisation, hydrosilylation, polysiloxane electrolytes for lithium ion batteries, silanes for PBX materials, octafunctionalized polyhedral oligomeric silsesquioxanes (POSS), POSS hybrids, sol-gel hydrogenation catalysts, silane modification of silica, sol-gel energy storage, silicate grout stabilisation, GeoPolymer concretes, aerogel insulating foams, "Phaco-Ersatz" Accommodating Gel-Intraocular Lens technologies...
June 1, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/28553396/a-rare-case-of-repeated-migration-and-transurethral-extrusion-of-ventriculoperitoneal-shunt
#20
Asra Al Fauzi, Wahjoe Djatisoesanto, Joni Wahyuhadi, Muhammad Arifin Parenrengi, Agus Turchan
Bladder migration and transurethral extrusion is an extremely rare complication of ventriculoperitoneal (VP) shunt. Only eight cases have been reported in the English literature since 1995. We report a case of a 4-year-old boy with cerebral palsy, hydrocephalus, and VP shunted on both sides who presented with a protruded distal VP shunt from his urethral orifice. The patient was reported for having previous shunt extrusion through the anus. The patient was treated on by a multidisciplinary approach, involving a neurosurgeon and urologist...
January 2017: Journal of Pediatric Neurosciences
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