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ultrasound AND contrast media

Michael D Witting, Siamak Moayedi, Kathy Dunning, Lisa S Babin, Brad M Cogan
BACKGROUND: After an index case of contrast-associated compartment syndrome, an urban hospital instituted a protocol limiting high-speed injection to intravenous (IV) lines started proximal to the forearm and testing those lines before contrast injection. OBJECTIVE: In this article, we estimate the safety and efficacy of high-speed injection using this protocol in patients with IV lines inserted under ultrasound guidance. METHODS: In an ambispective study, we enrolled prospective cohorts of ED patients requiring high-speed radiographic contrast media injection (≥3...
October 17, 2016: Journal of Emergency Medicine
Zoe Herreras, Montserrat Cofán, Marta Catalan, Carlos Calvo, Montserrat Pinyol, Antonio J Amor, Rosa Gilabert, Emilio Ros, Aleix Sala-Vila, Emilio Ortega
Consistent evidence supports the pro-atherogenic properties of dietary trans-fatty acids (TFAs). However, there are no clinical data on TFA intake and atheroma plaque. We cross sectionally investigated whether the proportion of total C18:1 TFA in red blood cells (RBCs), which mirrors dietary TFA intake, independently relates to carotid plaque prevalence in subjects with new-onset type 2 diabetes mellitus without prior cardiovascular disease (n=101, 56% men, mean age 61 years) and age- and sex-matched controls (n=96)...
September 7, 2016: Journal of Nutritional Biochemistry
Trishan Patel, Amy Elphick, James E Jackson, Claire L Shovlin
OBJECTIVE: To evaluate if injection of intravenous particles may provoke migraines in subjects with right-to-left shunts due to pulmonary arteriovenous malformations (AVMs). BACKGROUND: Migraine headaches commonly affect people with hereditary hemorrhagic telangiectasia (HHT), especially those with pulmonary AVMs that provide right-to-left shunts. In our clinical practice, patients occasionally reported acute precipitation of migraine headaches following injection of technetium-labeled albumin macroaggregates for nuclear medicine scans...
October 11, 2016: Headache
Jonathan Zipfel, Adrian Kastler, Laurent Tatu, Julien Behr, Rachid Kechidi, Bruno Kastler
BACKGROUND: Two studies recently reported that computed tomography (CT) guided infiltration of the greater occipital nerve at its intermediate site allows a high efficacy rate with long-lasting pain relief following procedure in occipital neuralgia and in various craniofacial pain syndromes. OBJECTIVE: The purpose of our study was to evaluate the technical feasibility and safety of ultrasound-guided intermediate site greater occipital nerve infiltration. STUDY DESIGN: Retrospective study...
September 2016: Pain Physician
Angela Tagetti, Sara Bonafini, Marco Zaffanello, Maria V Benetti, Francesco Dalle Vedove, Emma Gasperi, Paolo Cavarzere, Rossella Gaudino, Giorgio Piacentini, Pietro Minuz, Claudio Maffeis, Franco Antoniazzi, Cristiano Fava
INTRODUCTION: Both sleep-disordered breathing (SDB) and high blood pressure (BP) occur more frequently among obese children than among normal weight children, and this may be due to endothelial dysfunction and worsened arterial stiffness. The aim of this study was to evaluate the possible association between SDB and BP, and the possible role of endothelial function and local and systemic arterial stiffness in a sample of obese children asymptomatic for sleep disturbances. MATERIALS AND METHODS: Thirty-nine obese children were included in the study...
September 17, 2016: Journal of Hypertension
Yan-Ting Shiu, Silvio H Litovsky, Alfred K Cheung, Daniel B Pike, Jason Chieh Sheng Tey, Yingying Zhang, Carlton J Young, Michelle Robbin, Kenneth Hoyt, Michael Allon
BACKGROUND AND OBJECTIVES: Arteriovenous fistula maturation requires an increase in the diameter and blood flow of the feeding artery and the draining vein after its creation. The structural properties of the native vessels may affect the magnitude of these changes. We hypothesized that an increase in the collagen content of the vascular media (medial fibrosis) preoperatively would impair vascular dilation and thereby, limit the postoperative increase in arteriovenous fistula diameter and blood flow and clinical arteriovenous fistula maturation...
September 7, 2016: Clinical Journal of the American Society of Nephrology: CJASN
G Currie, J Flynn, M Lindhardt, H Mischak, P Rossing, C Delles
OBJECTIVE: Microalbuminuria (MA) is a marker of diabetic nephropathy (DN) but also indicates subclinical inflammation and vascular disease, limiting its sensitivity and specificity for early prediction of DN in type 2 diabetes. A urinary proteomic classifier based on 273 peptides (CKD273) shows promise for early detection of DN; however, the influence of inflammation and subclinical vascular disease on CKD27 is unknown. DESIGN AND METHOD: To dissect the relationship between CKD273, vascular phenotypes and inflammation without the confounding influence of MA we studied 145 normoalbuminuric patients with Type 2 diabetes participating in the PRIORITY (Proteomic prediction and Renin angiotensin aldosterone system Inhibition prevention Of early diabetic nephRopathy In TYpe 2 diabetes with normoalbuminuria) trial...
September 2016: Journal of Hypertension
Yan Liu, Yuecheng Shen, Cheng Ma, Junhui Shi, Lihong V Wang
Ultrasound-modulated optical tomography (UOT) images optical contrast deep inside scattering media. Heterodyne holography based UOT is a promising technique that uses a camera for parallel speckle detection. In previous works, the speed of data acquisition was limited by the low frame rates of conventional cameras. In addition, when the signal-to-background ratio was low, these cameras wasted most of their bits representing an informationless background, resulting in extremely low efficiencies in the use of bits...
June 6, 2016: Applied Physics Letters
Andrea Michelli, Stella Bernardi, Andrea Grillo, Emiliano Panizon, Matteo Rovina, Moreno Bardelli, Renzo Carretta, Bruno Fabris
BACKGROUND: Malignant hypertension is a condition characterized by severe hypertension and multi-organ ischemic complications. Albeit mortality and renal survival have improved with antihypertensive therapy, progression to end-stage renal disease remains a significant cause of morbidity and mortality. The underlying cause of malignant hypertension, which can be primary or secondary hypertension, is often difficult to identify and this can substantially affect the treatment outcomes, as we report here...
2016: BMC Nephrology
Monika Frysz, Kevin Deere, Debbie A Lawlor, Li Benfield, Jon H Tobias, Celia L Gregson
Osteoporosis and cardiovascular disease(CVD) are both common causes of morbidity and mortality. Previous studies, mainly of people over 60 years, suggest a relationship between these conditions. Our aim was to determine the association between bone characteristics and CVD markers in younger and middle-aged individuals. Women (n = 3,366) and their adolescent offspring (n= 4,368) from the UK population-based cohort study, Avon Longitudinal Study of Parents and Children(ALSPAC), were investigated. We measured total body(TB) and hip BMD, TB bone area(BA) and bone mineral content(BMC) by DXA, and carotid intima-media thickness(cIMT) by high-resolution ultrasound...
June 30, 2016: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
Andrea Magarotto, Stefania Orlando, Marina Coletta, Dario Conte, Mirella Fraquelli, Flavio Caprioli
The implementation of cross-sectional imaging techniques for the clinical management of Crohn's disease patients has steadily grown over the recent years, thanks to a series of technological advances, including the evolution of contrast media for magnetic resonance, computed tomography and bowel ultrasound. This has resulted in a continuous improvement of diagnostic accuracy and capability to detect Crohn's disease-related complications. Additionally, a progressive widening of indications for cross-sectional imaging in Crohn's disease has been put forward, thus leading to hypothesize that in the near future imaging techniques can increasingly complement endoscopy in most clinical settings, including the grading of disease activity and the assessment of mucosal healing or Crohn's disease post-surgical recurrence...
September 2016: Digestive and Liver Disease
Keisuke Fukuda, Akihiro Higashimori, Yoshiaki Yokoi
Endovascular treatment of chronic mesenteric ischemia in patients with impaired renal function or allergy to contrast media is a challenging procedure because angiography requires iodinated contrast media for accurate diagnosis and interventional procedures. Superior mesenteric artery stenting without contrast angiography is described in an 81-year-old woman with cardiovascular disease and chronic kidney disease (CKD) stage 5. Balloon angioplasty and stent placement were performed successfully using intravascular ultrasound, pressure wire, surface ultrasound, and fluoroscopy...
August 2016: Annals of Vascular Surgery
Mario Meola, Sara Samoni, Ilaria Petrucci, Claudio Ronco
Acute cortical necrosis and hemolytic uremic syndrome (HUS) are 2 clinical scenarios of parenchymal acute kidney injury (AKI) related to renal microvascular injury. Acute cortical necrosis is a rare condition related to an ischemic necrosis of renal cortex. Necrotic lesions can be due to several injuries and may be focal, multifocal or diffuse. Renal necrotic lesions become visible with ultrasound only after renal recovery. HUS is a rare disease characterized by hemolytic anemia, thrombocytopenia and AKI. Color Doppler ultrasound is useful during diagnostic and follow-up phase...
2016: Contributions to Nephrology
Mario Meola, Sara Samoni, Ilaria Petrucci, Claudio Ronco
Acute tubular necrosis (ATN) is the most common type of acute kidney injury (AKI) related to parenchymal damage (90% of cases). It may be due to a direct kidney injury, such as sepsis, drugs, toxins, contrast media, hemoglobinuria and myoglobinuria, or it may be the consequence of a prolonged systemic ischemic injury. Conventional ultrasound (US) shows enlarged kidneys with hypoechoic pyramids. Increased volume is largely sustained by the increase of anteroposterior diameter, while longitudinal axis usually maintains its normal length...
2016: Contributions to Nephrology
David B Hanna, Mengye Guo, Petra Bůžková, Tracie L Miller, Wendy S Post, James H Stein, Judith S Currier, Richard A Kronmal, Matthew S Freiberg, Siiri N Bennett, Cecilia M Shikuma, Kathryn Anastos, Yanjie Li, Russell P Tracy, Howard N Hodis, Joseph A Delaney, Robert C Kaplan
BACKGROUND: Age and human immunodeficiency virus (HIV) treatment may affect the association of HIV infection with atherosclerosis. METHODS: We used identical carotid artery B-mode ultrasonographic methods in 5 cohorts participating in the National Heart, Lung, and Blood Institute HIV-CVD Collaborative to measure intima-media thickness of the right far wall of the common carotid artery (CCA-IMT) and carotid artery bifurcation (BIF-IMT) between 2010 and 2013. Participants aged 6-75 years were either HIV infected or uninfected...
July 15, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
C Hackl, D Schacherer, M Anders, L M Wiedemann, A Mohr, H J Schlitt, C Stroszczynski, F Tranquart, E M Jung
PURPOSE: Aim of the present study was to investigate the sensitivity of high resolution ultrasound (HRU), standard contrast-enhanced ultrasound (CEUS) and CEUS using a novel vascular endothelial growth factor receptor 2 (VEGFR2)-targeted contrast agent for the detection of hepatic metastases in a mouse model of colorectal cancer using clinical standard technology. MATERIALS AND METHODS: The human colon cancer cell line HT29, transfected with luciferase cDNA for in vivo bioluminescence monitoring, was injected intrasplenically into CB17...
June 2016: Ultraschall in der Medizin
Runqing Huang, Sahar S Abdelmoneim, Caroline A Ball, Lara F Nhola, Ann M Farrell, Steven Feinstein, Sharon L Mulvagh
BACKGROUND: Intraplaque neovascularization is considered an important indicator of plaque vulnerability. Contrast-enhanced ultrasound (CEUS) of carotid arteries improves imaging of carotid intima-media thickness and permits real-time visualization of neovascularization of the atherosclerotic plaque. The authors conducted a systematic review and meta-analysis to evaluate the accuracy of CEUS-detected carotid atherosclerotic plaque. METHODS: A systematic search was performed to identify studies published in the MEDLINE, Embase, Scopus, and Web of Science databases from 2004 to June 2015...
June 2016: Journal of the American Society of Echocardiography
Manse Kim, Jong Hyun Lee, Se Eun Kim, Seong Soo Kang, Giyoong Tae
To enhance the detection limit of ultrasound (US) imaging, ultrasound enhanced-contrast agents (UECAs) that can go preferentially to the target tissue such as a tumor and amplify the US signal have been developed. However, nanosized UECAs among various UECAs developed are very limited to clearly demonstrate proper ability for selective tumor detection by US imaging upon their intravenous injection. In this study, we prepared CaCO3 nanoparticles that were formed inside a flexible and biocompatible pluronic-based nanocarrier...
April 6, 2016: ACS Applied Materials & Interfaces
Michael J Callahan, Jennifer M Talmadge, Robert MacDougall, Carlo Buonomo, George A Taylor
OBJECTIVE: Enteric contrast media are commonly administered for diagnostic cross-sectional imaging studies in the pediatric population. The purpose of this manuscript is to review the use of enteric contrast media for CT, MRI, and ultrasound in infants, children, and adolescents and to share our experiences at a large tertiary care pediatric teaching hospital. CONCLUSION: The use of enteric contrast material for diagnostic imaging in infants and children continues to evolve with advances in imaging technology and available enteric contrast media...
May 2016: AJR. American Journal of Roentgenology
Ai-Ho Liao, Ying-Jui Lu, Chi-Ray Hung, Meng-Yu Yang
Liquid microemulsions appropriate for topical application were obtained by increasing their viscosity through the addition of thickening agents. The present study first assessed the usefulness of ultrasound (US) plus US contrast agent, microbubbles (MBs), in agarose gel for enhancing transdermal drug delivery. The effect of US plus MBs in agarose gel on the penetration of the skin by magnesium ascorbyl phosphate (MAP) was explored both in vitro and in vivo. In the in vitro experiments, the stability of MBs was investigated by examining the penetration of MAP by the model drug, Evans blue, in two media: an agarose phantom and pig skin...
April 1, 2016: Materials Science & Engineering. C, Materials for Biological Applications
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