keyword
MENU ▼
Read by QxMD icon Read
search

Integrated Disease Surveillance

keyword
https://www.readbyqxmd.com/read/29452594/comparative-immunogenicity-of-preparations-of-yeast-derived-dengue-oral-vaccine-candidate
#1
Jyotiranjan Bal, Nguyen Ngoc Luong, Jisang Park, Ki-Duk Song, Yong-Suk Jang, Dae-Hyuk Kim
BACKGROUND: Dengue is listed as a neglected tropical disease by the Center for Disease Control and Preservation, as there are insufficient integrated surveillance strategies, no effective treatment, and limited licensed vaccines. Consisting of four genetically distinct serotypes, dengue virus (DENV) causes serious life-threatening infections due to its complexity. Antibody-dependent enhancement by pre-existing cross-reactive as well as homotypic antibodies further worsens the clinical symptoms of dengue...
February 16, 2018: Microbial Cell Factories
https://www.readbyqxmd.com/read/29451312/yoda-map3k-kinase-regulates-plant-immune-responses-conferring-broad-spectrum-disease-resistance
#2
Sara Sopeña-Torres, Lucía Jordá, Clara Sánchez-Rodríguez, Eva Miedes, Viviana Escudero, Sanjay Swami, Gemma López, Mariola Piślewska-Bednarek, Ines Lassowskat, Justin Lee, Yangnan Gu, Sabine Haigis, Danny Alexander, Sivakumar Pattathil, Antonio Muñoz-Barrios, Pawel Bednarek, Shauna Somerville, Paul Schulze-Lefert, Michael G Hahn, Dierk Scheel, Antonio Molina
Mitogen-activated protein kinases (MAPKs) cascades play essential roles in plants by transducing developmental cues and environmental signals into cellular responses. Among the latter are microbe-associated molecular patterns perceived by pattern recognition receptors (PRRs), which trigger immunity. We found that YODA (YDA) - a MAPK kinase kinase regulating several Arabidopsis developmental processes, like stomatal patterning - also modulates immune responses. Resistance to pathogens is compromised in yda alleles, whereas plants expressing the constitutively active YDA (CA-YDA) protein show broad-spectrum resistance to fungi, bacteria, and oomycetes with different colonization modes...
February 16, 2018: New Phytologist
https://www.readbyqxmd.com/read/29444685/prevalence-and-correlates-of-hiv-infection-among-men-who-inject-drugs-in-a-remote-area-of-vietnam
#3
Van T Nghiem, Thanh C Bui, Patrick P Nadol, Son H Phan, Binh T Kieu, Ryan Kling, Theodore M Hammett
BACKGROUND: Lack of information on the HIV epidemic among men who inject drugs (MWID) in northwestern Vietnam, a remote area, may hamper national efforts to control the disease. We examined HIV prevalence, needle-syringe sharing behaviors, and associated factors among MWID in three areas of northwestern Vietnam. METHODS: We used descriptive analysis to report the characteristics, frequency of risk behaviors, and of access to healthcare services among the MWID. Univariable logistic regression was used to assess the associations between the HIV infection, needle-syringe sharing behaviors, and their independent variables...
February 14, 2018: Harm Reduction Journal
https://www.readbyqxmd.com/read/29442055/incidence-of-statin-drug-interactions-in-croatian-community-pharmacy
#4
I Samardzic, I Benkovic, V Bacic Vrca
Statins are among the most frequently issued drugs that patients usually need to take for a lifetime. They are often an integral part of a polytherapeutic approach in preventing and treating cardiovascular diseases. As such, they might often interact with drugs prescribed for treating acute and chronic conditions. A pharmacist is the final professional control before a drug reaches the patient and his role in preventing drug-drug interactions is crucial. The objective of this research was to analyse the incidence and relevance of potential drug interactions with statins in community pharmacy...
March 1, 2017: Die Pharmazie
https://www.readbyqxmd.com/read/29440217/using-big-data-to-improve-cardiovascular-care-and-outcomes-in-china-a-protocol-for-the-chinese-electronic-health-records-research-in-yinzhou-cherry-study
#5
Hongbo Lin, Xun Tang, Peng Shen, Dudan Zhang, Jinguo Wu, Jingyi Zhang, Ping Lu, Yaqin Si, Pei Gao
INTRODUCTION: Data based on electronic health records (EHRs) are rich with individual-level longitudinal measurement information and are becoming an increasingly common data source for clinical risk prediction worldwide. However, few EHR-based cohort studies are available in China. Harnessing EHRs for research requires a full understanding of data linkages, management, and data quality in large data sets, which presents unique analytical opportunities and challenges. The purpose of this study is to provide a framework to establish a uniquely integrated EHR database in China for scientific research...
February 12, 2018: BMJ Open
https://www.readbyqxmd.com/read/29434671/validation-of-american-joint-committee-on-cancer-eighth-staging-system-among-prostate-cancer-patients-treated-with-radical-prostatectomy
#6
Omar Abdel-Rahman
Background: The objective in this paper was to validate the prognostic performance of the American Joint Committee on Cancer (AJCC) 7th and 8th systems among prostate cancer patients treated with radical prostatectomy. Methods: The surveillance, epidemiology and end results (SEER) database (2006-2014) was accessed through the SEER*Stat program and AJCC 7th and 8th editions were calculated utilizing T, N and M stages, histological grade group, as well as baseline prostatic-specific antigen (PSA)...
February 2018: Therapeutic Advances in Urology
https://www.readbyqxmd.com/read/29428176/the-impact-of-immunization-programs-on-10-vaccine-preventable-diseases-in-italy-1900-2015
#7
Patrizio Pezzotti, Stefania Bellino, Francesca Prestinaci, Simone Iacchini, Francesca Lucaroni, Laura Camoni, Maria Maddalena Barbieri, Walter Ricciardi, Paola Stefanelli, Giovanni Rezza
BACKGROUND: Vaccination has determined a dramatic decline in morbidity and mortality from infectious diseases over the last century. However, low perceived risk of the infectious threat and increased concern about vaccines' safety led to a reduction in vaccine coverage, with increased risk of disease outbreaks. METHODS: Annual surveillance data of nationally communicable infectious diseases in Italy between 1900 and 2015 were used to derive trends in morbidity and mortality rates before and after vaccine introduction, focusing particularly on the effect of vaccination programs...
February 7, 2018: Vaccine
https://www.readbyqxmd.com/read/29426659/current-status-of-cerebrospinal-meningitis-and-impact-of-the-2015-meningococcal-c-vaccination-in-kebbi-northwest-nigeria
#8
Olumide Ajibola, Semeeh Akinwale Omoleke, Olusola Akintoye Omisakin
INTRODUCTION: Following the significant reduction of Neisseria meningitidis A (NmA) in most parts of northern Nigeria, a new strain of Neisseria meningitidis C (NmC) emerged in 2013 causing outbreaks in the north and recently spreading to southern parts of the Nigeria. This study provides detailed epidemiological investigation in the last four years. METHODS: Analysis of confirmed and suspected cases of meningitis in Kebbi, Nigeria from 2014 to June 2017 detected through Integrated Disease Surveillance and Response...
February 6, 2018: Vaccine
https://www.readbyqxmd.com/read/29422899/sensing-bacterial-induced-dna-damaging-effects-via-natural-killer-group-2-member-d-immune-receptor-from-dysbiosis-to-autoimmunity-and-carcinogenesis
#9
REVIEW
J Luis Espinoza, Mika Minami
The human genome is constantly exposed to exogenous and endogenous DNA damaging factors that frequently cause DNA damages. Unless repaired, damaged DNA can result in deleterious mutations capable of causing malignant transformation. Accordingly, cells have developed an advanced and effective surveillance system, the DNA damage response (DDR) pathway, which maintains genetic integrity. In addition to well-defined outcomes, such as cell cycle arrest, apoptosis, and senescence, another consequence of DDR activation is the induction of natural killer group 2 member D ligands (NKG2D-Ls) on the surface of stressed cells...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29419921/the-evolving-contribution-of-non-communicable-diseases-ncds-to-maternal-mortality-in-jamaica-1998-2015-a-population-based-study
#10
Affette M McCaw-Binns, Leroy V Campbell, Simone S Spence
OBJECTIVE: Describe trends in indirect cause-specific pregnancy-related mortality from 1998-2015. DESIGN: Secondary analysis of annual, national cross-sectional database of maternal and late maternal deaths, identified through active surveillance of deaths among women 10-50 years. SETTING: Jamaica, a middle-income Caribbean country. POPULATION: Maternal and late maternal deaths. METHODS: Descriptive trend analyses of demographic and cause-specific maternal and pregnancy-related mortality ratios undertaken comparing the periods 1998-2003, 2004-9 and 2010-15...
February 8, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29416939/maturation-of-tertiary-lymphoid-structures-and-recurrence-of-stage-ii-and-iii-colorectal-cancer
#11
Florian Posch, Karina Silina, Sebastian Leibl, Axel Mündlein, Holger Moch, Alexander Siebenhüner, Panagiotis Samaras, Jakob Riedl, Michael Stotz, Joanna Szkandera, Herbert Stöger, Martin Pichler, Roger Stupp, Maries van den Broek, Peter Schraml, Armin Gerger, Ulf Petrausch, Thomas Winder
Tertiary lymphoid structures (TLS) are associated with favorable outcome in non-metastatic colorectal carcinoma (nmCRC), but the dynamics of TLS maturation and its association with effective anti-tumor immune surveillance in nmCRC are unclear. Here, we hypothesized that not only the number of TLS but also their composition harbors information on recurrence risk in nmCRC. In a comprehensive molecular, tissue, laboratory, and clinical analysis of 109 patients with stage II/III nmCRC, we assessed TLS numbers and degree of maturation in surgical specimens by multi-parameter immunofluorescence of follicular dendritic cell (FDC) and germinal center (GC) markers...
2018: Oncoimmunology
https://www.readbyqxmd.com/read/29415432/impact-of-rna-degradation-on-viral-diagnosis-an-understated-but-essential-step-for-the-successful-establishment-of-a-diagnosis-network
#12
Damarys Relova, Liliam Rios, Ana M Acevedo, Liani Coronado, Carmen L Perera, Lester J Pérez
The current global conditions, which include intensive globalization, climate changes, and viral evolution among other factors, have led to an increased emergence of viruses and new viral diseases; RNA viruses are key drivers of this evolution. Laboratory networks that are linked to central reference laboratories are required to conduct both active and passive environmental surveillance of this complicated global viral environment. These tasks require a continuous exchange of strains or field samples between different diagnostic laboratories...
February 6, 2018: Veterinary Sciences
https://www.readbyqxmd.com/read/29415029/rates-and-risk-factors-for-human-cutaneous-anthrax-in-the-country-of-georgia-national-surveillance-data-2008-2015
#13
Ana Kasradze, Diana Echeverria, Khatuna Zakhashvili, Christian Bautista, Nicholas Heyer, Paata Imnadze, Veriko Mitrskhulava
INTRODUCTION: Anthrax is endemic in the country of Georgia. The most common cutaneous anthrax form accounts for 95% of anthrax cases and often is self-resolving. Humans are infected from processing contaminated animal products, contacting sick animals, or by insect bites. OBJECTIVE: We aimed to describe the burden of human cutaneous anthrax and associated risk factors using the national surveillance data. METHODS: We extracted all human cutaneous anthrax cases from Electronic Integrated Disease Surveillance System (EIDSS) from 1 January 2008 to 31 December 2015...
2018: PloS One
https://www.readbyqxmd.com/read/29408410/the-role-of-mtor-mediated-signaling-in-the-regulation-of-cellular-migration
#14
REVIEW
Ailsa K Holroyd, Alison M Michie
Mechanistic target for rapamycin (mTOR) is a serine/threonine protein kinase that forms two distinct complexes mTORC1 and mTORC2, integrating mitogen and nutrient signals to regulate cell survival and proliferation; processes which are commonly deregulated in human cancers. mTORC1 and mTORC2 have divergent molecular associations and cellular functions: mTORC1 regulates in mRNA translation and protein synthesis, while mTORC2 is involved in the regulation of cellular survival and metabolism. Through AKT phosphorylation/activation, mTORC2 has also been reported to regulate cell migration...
February 3, 2018: Immunology Letters
https://www.readbyqxmd.com/read/29408188/a-retrospective-assessment-of-the-completeness-and-timeliness-of-meningococcal-disease-notifications-in-the-republic-of-ireland-over-a-16-year-period-1999-2015
#15
P O'Lorcain, D E Bennett, S L Morgan, R J Cunney, S M Cotter, M T Cafferkey, D M O'Flanagan
OBJECTIVES: To assess how invasive meningococcal disease (IMD) records held by the Irish Meningitis & Sepsis Reference Laboratory (IMSRL) compare to records of IMD notifications reported on the national integrated electronic Computerised Infectious Disease Reporting (CIDR) system. STUDY DESIGN: We assessed the completeness, data quality and timeliness of IMD notifications and reference laboratory records for the period between 01 July 1999 and 30 June 2015 by identifying discrepant and/or missing data items in a matched case data set and by measuring the timeliness of case reporting...
January 22, 2018: Public Health
https://www.readbyqxmd.com/read/29404294/short-message-service-prompted-mouth-self-examination-in-oral-cancer-patients-as-an-alternative-to-frequent-hospital-based-surveillance
#16
Sagar Vaishampayan, Akshat Malik, Prashant Pawar, Kavi Arya, Pankaj Chaturvedi
Introduction: Oral squamous cell carcinoma (OSCC) are amongst commonest cancer in the Indian sub-continent. After treatment, these patients require frequent followup to look for recurrences/second primary. Mouth Self Examination (MSE) has a great potential in all levels of prevention of oral cancer. However, the compliance to self-examination has been reported as poor. Mobile phone is a cheap and effective way to reach out to people. Short Message Service (SMS) is extremely popular can be a very effective motivational and interactive tool in health care setting...
October 2017: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29403115/revision-of-clinical-case-definitions-influenza-like-illness-and-severe-acute-respiratory-infection
#17
Julia Fitzner, Saba Qasmieh, Anthony Wayne Mounts, Burmaa Alexander, Terry Besselaar, Sylvie Briand, Caroline Brown, Seth Clark, Erica Dueger, Diane Gross, Siri Hauge, Siddhivinayak Hirve, Pernille Jorgensen, Mark A Katz, Ali Mafi, Mamunur Malik, Margaret McCarron, Tamara Meerhoff, Yuichiro Mori, Joshua Mott, Maria Teresa da Costa Olivera, Justin R Ortiz, Rakhee Palekar, Helena Rebelo-de-Andrade, Loes Soetens, Ali Ahmed Yahaya, Wenqing Zhang, Katelijn Vandemaele
The formulation of accurate clinical case definitions is an integral part of an effective process of public health surveillance. Although such definitions should, ideally, be based on a standardized and fixed collection of defining criteria, they often require revision to reflect new knowledge of the condition involved and improvements in diagnostic testing. Optimal case definitions also need to have a balance of sensitivity and specificity that reflects their intended use. After the 2009-2010 H1N1 influenza pandemic, the World Health Organization (WHO) initiated a technical consultation on global influenza surveillance...
February 1, 2018: Bulletin of the World Health Organization
https://www.readbyqxmd.com/read/29401726/epidemiological-characteristics-and-spatial-temporal-distribution-of-hand-foot-and-mouth-disease-in-chongqing-china-2009-2016
#18
Li Qi, Wenge Tang, Han Zhao, Hua Ling, Kun Su, Hua Zhao, Qin Li, Tao Shen
(1) Objective: Even with licensed vaccine for enterovirus 71 (EV71) put into market in 2016 in China, hand, foot, and mouth disease (HFMD) is still a threat for children's health in Chongqing. We described the epidemiological characteristics and spatial-temporal patterns of HFMD in Chongqing from 2009 to 2016, in order to provide information and evidence for guiding public health response and intervention. (2) Methods: We retrieved the HFMD surveillance data from January 2009 to December 2016 from "National Disease Reporting Information System", and then analyzed demographic and geographical information integrally...
February 5, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29390021/development-of-a-loop-mediated-isothermal-amplification-lamp-assay-for-rapid-screening-of-ticks-and-fleas-for-spotted-fever-group-rickettsia
#19
Bruce H Noden, Jaclyn Martin, Yisel Carrillo, Justin L Talley, Francisco M Ochoa-Corona
BACKGROUND: The importance of tick and flea-borne rickettsia infections is increasingly recognized worldwide. While increased focus has shifted in recent years to the development of point-of-care diagnostics for various vector-borne diseases in humans and animals, little research effort has been devoted to their integration into vector surveillance and control programs, particularly in resource-challenged countries. One technology which may be helpful for large scale vector surveillance initiatives is loop-mediated isothermal amplification (LAMP)...
2018: PloS One
https://www.readbyqxmd.com/read/29387688/a-smartphone-based-application-improves-the-accuracy-completeness-and-timeliness-of-cattle-disease-reporting-and-surveillance-in-ethiopia
#20
Tariku Jibat Beyene, Fentahun Asfaw, Yitbarek Getachew, Takele Beyene Tufa, Iain Collins, Ashenafi Feyisa Beyi, Crawford W Revie
Accurate disease reporting, ideally in near real time, is a prerequisite to detecting disease outbreaks and implementing appropriate measures for their control. This study compared the performance of the traditional paper-based approach to animal disease reporting in Ethiopia to one using an application running on smartphones. In the traditional approach, the total number of cases for each disease or syndrome was aggregated by animal species and reported to each administrative level at monthly intervals; while in the case of the smartphone application demographic information, a detailed list of presenting signs, in addition to the putative disease diagnosis were immediately available to all administrative levels via a Cloud-based server...
2018: Frontiers in Veterinary Science
keyword
keyword
75360
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"