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Integrated Disease Surveillance

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https://www.readbyqxmd.com/read/28542223/measuring-changes-in-transmission-of-neglected-tropical-diseases-malaria-and-enteric-pathogens-from-quantitative-antibody-levels
#1
Benjamin F Arnold, Mark J van der Laan, Alan E Hubbard, Cathy Steel, Joseph Kubofcik, Katy L Hamlin, Delynn M Moss, Thomas B Nutman, Jeffrey W Priest, Patrick J Lammie
BACKGROUND: Serological antibody levels are a sensitive marker of pathogen exposure, and advances in multiplex assays have created enormous potential for large-scale, integrated infectious disease surveillance. Most methods to analyze antibody measurements reduce quantitative antibody levels to seropositive and seronegative groups, but this can be difficult for many pathogens and may provide lower resolution information than quantitative levels. Analysis methods have predominantly maintained a single disease focus, yet integrated surveillance platforms would benefit from methodologies that work across diverse pathogens included in multiplex assays...
May 19, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28534612/sers-activated-platforms-for-immunoassay-probes-encoding-methods-and-applications
#2
Zhuyuan Wang, Shenfei Zong, Lei Wu, Dan Zhu, Yiping Cui
Owing to their excellent multiplexing ability, high sensitivity, and large dynamic range, immunoassays using surface-enhanced Raman scattering (SERS) as the readout signal have found prosperous applications in fields such as disease diagnosis, environmental surveillance, and food safety supervision. Various ever-increasing demands have promoted SERS-based immunoassays from the classical sandwich-type ones to those integrated with fascinating automatic platforms (e.g., test strips and microfluidic chips). As recent years have witnessed impressive progress in SERS immunoassays, we try to comprehensively cover SERS-based immunoassays from their basic working principles to specific applications...
May 23, 2017: Chemical Reviews
https://www.readbyqxmd.com/read/28534030/combining-slaughterhouse-surveillance-data-with-cattle-tracing-scheme-and-environmental-data-to-quantify-environmental-risk-factors-for-liver-fluke-in-cattle
#3
Giles T Innocent, Lucy Gilbert, Edward O Jones, James E McLeod, George Gunn, Iain J McKendrick, Steve D Albon
Liver fluke infection causes serious disease (fasciolosis) in cattle and sheep in many regions of the world, resulting in production losses and additional economic consequences due to condemnation of the liver at slaughter. Liver fluke depends on mud snails as an intermediate host and infect livestock when ingested through grazing. Therefore, environmental factors play important roles in infection risk and climate change is likely to modify this. Here, we demonstrate how slaughterhouse data can be integrated with other data, including animal movement and climate variables to identify environmental risk factors for liver fluke in cattle in Scotland...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28511269/the-role-of-birds-in-arboviral-disease-surveillance-in-harris-county-and-the-city-of-houston-texas
#4
Lauren Wilkerson, Martin Reyna Nava, Cheryl Battle-Freeman, Amelia Travassos da Rosa, Hilda Guzman, Robert Tesh, Mustapha Debboun
Avian arboviral surveillance is an integral part of any disease-based integrated mosquito control program. The Harris County Public Health Mosquito and Vector Control Division has performed arboviral surveillance in the wild birds of Harris County and the City of Houston since 1965. Blood samples from live trapped birds were tested for arboviral antibodies to West Nile virus (WNV), St. Louis encephalitis, Eastern equine encephalitis, and Western equine encephalitis. A dead bird surveillance program was created in 2002 with the arrival of WNV in Harris County...
January 2017: U.S. Army Medical Department Journal
https://www.readbyqxmd.com/read/28502807/augmenting-brain-metabolism-to-increase-macro-and-chaperone-mediated-autophagy-for-decreasing-neuronal-proteotoxicity-and-aging
#5
REVIEW
Ben Loos, Daniel J Klionsky, Esther Wong
Accumulation of toxic protein aggregates in the nerve cells is a hallmark of neuronal diseases and brain aging. Mechanisms to enhance neuronal surveillance to improve neuronal proteostasis have a direct impact on promoting neuronal health and forestalling age-related decline in brain function. Autophagy is a lysosomal degradative pathway pivotal for neuronal protein quality control. Different types of autophagic mechanisms participate in protein handling in neurons. Macroautophagy targets misfolded and aggregated proteins in autophagic vesicles to the lysosomes for destruction, while chaperone-mediated autophagy (CMA) degrades specific soluble cytosolic proteins delivered to the lysosomes by chaperones...
May 11, 2017: Progress in Neurobiology
https://www.readbyqxmd.com/read/28494844/west-nile-virus-surveillance-in-europe-moving-towards-an-integrated-animal-human-vector-approach
#6
Céline M Gossner, Laurence Marrama, Marianne Carson, Franz Allerberger, Paolo Calistri, Dimitrios Dilaveris, Sylvie Lecollinet, Dilys Morgan, Norbert Nowotny, Marie-Claire Paty, Danai Pervanidou, Caterina Rizzo, Helen Roberts, Friedrich Schmoll, Wim Van Bortel, Andrea Gervelmeyer
This article uses the experience of five European countries to review the integrated approaches (human, animal and vector) for surveillance and monitoring of West Nile virus (WNV) at national and European levels. The epidemiological situation of West Nile fever in Europe is heterogeneous. No model of surveillance and monitoring fits all, hence this article merely encourages countries to implement the integrated approach that meets their needs. Integration of surveillance and monitoring activities conducted by the public health authorities, the animal health authorities and the authorities in charge of vector surveillance and control should improve efficiency and save resources by implementing targeted measures...
May 4, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28492123/factors-associated-with-contracting-malaria-in-ward-29-of-shamva-district-zimbabwe-2014
#7
Gladwin Muchena, Notion Gombe, Lucia Takundwa, Mufuta Tshimanga, Donewell Bangure, Nyasha Masuka, Tsitsi Juru
BACKGROUND: Malaria cases at Wadzanayi Clinic in Shamva District, Zimbabwe, increased drastically, surpassing the epidemic threshold, in week four of December 2013. This rise was sustained, which necessitated an investigation of the outbreak. OBJECTIVES: To identify risk factors and system weaknesses to improve epidemic preparedness and response. METHODS: An unmatched 1:1 case-control study was conducted in Ward 29 of Shamva District in Zimbabwe...
April 25, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28488999/immunisation-information-systems-useful-tools-for-monitoring-vaccination-programmes-in-eu-eea-countries-2016
#8
Tarik Derrough, Kate Olsson, Vincenza Gianfredi, Francois Simondon, Harald Heijbel, Niklas Danielsson, Piotr Kramarz, Lucia Pastore-Celentano
Immunisation Information Systems (IIS) are computerised confidential population based-systems containing individual-level information on vaccines received in a given area. They benefit individuals directly by ensuring vaccination according to the schedule and they provide information to vaccine providers and public health authorities responsible for the delivery and monitoring of an immunisation programme. In 2016, the European Centre for Disease Prevention and Control (ECDC) conducted a survey on the level of implementation and functionalities of IIS in 30 European Union/European Economic Area (EU/EEA) countries...
April 27, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28486934/progression-of-the-epidemiological-transition-in-a-rural-south-african-setting-findings-from-population-surveillance-in-agincourt-1993-2013
#9
Chodziwadziwa W Kabudula, Brian Houle, Mark A Collinson, Kathleen Kahn, Francesc Xavier Gómez-Olivé, Samuel J Clark, Stephen Tollman
BACKGROUND: Virtually all low- and middle-income countries are undergoing an epidemiological transition whose progression is more varied than experienced in high-income countries. Observed changes in mortality and disease patterns reveal that the transition in most low- and middle-income countries is characterized by reversals, partial changes and the simultaneous occurrence of different types of diseases of varying magnitude. Localized characterization of this shifting burden, frequently lacking, is essential to guide decentralised health and social systems on the effective targeting of limited resources...
May 10, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28478826/novel-aspects-of-defensins-involvement-in-virus-induced-autoimmunity-in-the-central-nervous-system
#10
Evangelos I Kazakos, Jannis Kountouras, Stergios A Polyzos, Georgia Deretzi
Recent research on re-circulation of interstitial fluid from the brain parenchyma to the periphery and its inferred importance in immune surveillance dysregulation are changing our conceptualization of the pathophysiology of virus-induced autoimmunity. In this context, it is necessary to reassess the immunomodulatory properties of human defensins that are variably expressed by cerebral microglia, astrocytes and choroid plexus epithelial cells and exhibit complex and often confounding roles in neuroinflammatory processes...
May 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28477319/transition-of-care-in-congenital-heart-disease-ensuring-the-proper-handoff
#11
REVIEW
Angela Lee, Barbara Bailey, Geraldine Cullen-Dean, Sandra Aiello, Joanne Morin, Erwin Oechslin
BACKGROUND: With great advances in medical and surgical care, most congenital heart disease patients are living in to adulthood and require lifelong surveillance and expert care for adult onset complications. Care lapse and lack of successful transfer from pediatric to adult care put young adults at risk for increased morbidity and premature death. Hence, transition and transfer from pediatric to adult care is a crucial and critical process to provide access to specialized care and lifelong surveillance...
June 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28473308/sa%C3%A3%C2%BAde-na-copa-the-world-s-first-application-of-participatory-surveillance-for-a-mass-gathering-at-fifa-world-cup-2014-brazil
#12
Onicio Leal Neto, George Santiago Dimech, Marlo Libel, Wayner Vieira de Souza, Eduarda Cesse, Mark Smolinski, Wanderson Oliveira, Jones Albuquerque
BACKGROUND: The 2005 International Health Regulations (IHRs) established parameters for event assessments and notifications that may constitute public health emergencies of international concern. These requirements and parameters opened up space for the use of nonofficial mechanisms (such as websites, blogs, and social networks) and technological improvements of communication that can streamline the detection, monitoring, and response to health problems, and thus reduce damage caused by these problems...
May 4, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/28472440/a-global-cancer-surveillance-framework-within-noncommunicable-disease-surveillance-making-the-case-for-population-based-cancer-registries
#13
Marion Piñeros, Ariana Znaor, Les Mery, Freddie Bray
The growing burden of cancer among several major noncommunicable diseases (NCDs) requires national implementation of tailored public health surveillance. For many emerging economies where emphasis has traditionally been placed on the surveillance of communicable diseases, it is critical to understand the specificities of NCD surveillance and, within it, of cancer surveillance. We propose a general framework for cancer surveillance that permits monitoring the core components of cancer control. We examine communalities in approaches to the surveillance of other major NCDs as well as communicable diseases, illustrating key differences in the function, coverage, and reporting in each system...
January 1, 2017: Epidemiologic Reviews
https://www.readbyqxmd.com/read/28465831/interaction-between-the-gut-microbiome-and-mucosal-immune-system
#14
REVIEW
Na Shi, Na Li, Xinwang Duan, Haitao Niu
The gut microbiota, the largest symbiotic ecosystem with the host, has been shown to play important roles in maintaining intestinal homeostasis. Dysbiosis of the gut microbiome is caused by the imbalance between the commensal and pathogenic microbiomes. The commensal microbiome regulates the maturation of the mucosal immune system, while the pathogenic microbiome causes immunity dysfunction, resulting in disease development. The gut mucosal immune system, which consists of lymph nodes, lamina propria and epithelial cells, constitutes a protective barrier for the integrity of the intestinal tract...
2017: Military Medical Research
https://www.readbyqxmd.com/read/28465304/invasive-meningococcal-disease-in-the-veneto-region-of-italy-a-capture-recapture-analysis-for-assessing-the-effectiveness-of-an-integrated-surveillance-system
#15
Tatjana Baldovin, Roberta Lazzari, Silvia Cocchio, Patrizia Furlan, Chiara Bertoncello, Mario Saia, Francesca Russo, Vincenzo Baldo
BACKGROUND: Epidemiology of Neisseria meningitidis has been changing since the introduction of universal vaccination programmes against meningococcal serogroup C (MenC) and meningococcal serogroup B (MenB) has now become dominant. This study aimed to analyse the cases reported in institutional data recording systems to estimate the burden of invasive meningococcal diseases (IMDs) and assess the effectiveness of surveillance in Veneto region (Italy). METHODS: Analysis was performed from 2007 to 2014 on data recorded in different systems: Mandatory Notification System, National Surveillance of Invasive Bacterial Diseases System and Laboratories Surveillance System (LSS), which were pooled into a combined surveillance system (CSS) and hospital discharge records (HDRs)...
May 2, 2017: BMJ Open
https://www.readbyqxmd.com/read/28464015/forecasting-influenza-in-hong-kong-with-google-search-queries-and-statistical-model-fusion
#16
Qinneng Xu, Yulia R Gel, L Leticia Ramirez Ramirez, Kusha Nezafati, Qingpeng Zhang, Kwok-Leung Tsui
BACKGROUND: The objective of this study is to investigate predictive utility of online social media and web search queries, particularly, Google search data, to forecast new cases of influenza-like-illness (ILI) in general outpatient clinics (GOPC) in Hong Kong. To mitigate the impact of sensitivity to self-excitement (i.e., fickle media interest) and other artifacts of online social media data, in our approach we fuse multiple offline and online data sources. METHODS: Four individual models: generalized linear model (GLM), least absolute shrinkage and selection operator (LASSO), autoregressive integrated moving average (ARIMA), and deep learning (DL) with Feedforward Neural Networks (FNN) are employed to forecast ILI-GOPC both one week and two weeks in advance...
2017: PloS One
https://www.readbyqxmd.com/read/28458901/the-management-of-metastatic-radioiodine-refractory-differentiated-thyroid-cancer-requires-an-integrated-approach-including-both-directed-and-systemic-therapies
#17
Shamil D Cooray, Duncan J Topliss
SUMMARY: A 58-year-old man with metastatic radioiodine-refractory differentiated thyroid cancer (DTC) presented with left thigh and right flank numbness. He had known progressive and widespread bony metastases, for which he received palliative radiotherapy, and multiple bilateral asymptomatic pulmonary metastases. CT scan and MRI of the spine revealed metastases at right T10-L1 vertebrae with extension into the central canal and epidural disease at T10 and T11 causing cord displacement and canal stenosis but retention of spinal cord signal...
2017: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/28454988/physicians-perceptions-of-factors-influencing-the-treatment-decision-making-process-for-men-with-low-risk-prostate-cancer
#18
Kimberly Davis, Paula Bellini, Charlotte Hagerman, Riley Zinar, Daniel Leigh, Richard Hoffman, David Aaronson, Stephen Van Den Eeden, George Phillips, Kathryn Taylor
OBJECTIVE: To assess physicians' attitudes regarding multiple factors that may influence recommendations for AS vs. AT given the central role physicians play in the treatment-decision making process. METHODS: We conducted semi-structured interviews to assess factors that physicians consider important when recommending AS vs. AT, as well as physicians' perceptions of what their patients consider important in the decision. Participants included urologists (N=11), radiation oncologists (N=12), and primary care physicians (N=10), from both integrated and fee-for-service healthcare settings...
April 25, 2017: Urology
https://www.readbyqxmd.com/read/28453097/-description-of-the-process-of-preparation-and-response-of-local-health-authorities-facing-the-introduction-of-the-chikungunya-virus-in-colombia-2014
#19
Ángela P Alarcón-Cruz, Edgar Prieto-Suárez
Objective To describe the process of preparation and response of local health authorities in key public health issues while facing the introduction stage of an unusual virus: Chikungunya in Colombia in 2014. Methods A cross-sectional study was conducted using a survey that was developed for this study and sent to Public Health coordinators and to the person in charge of vector borne-diseases in the country's territorial entities. Results 23 out of the 35 territories at risk from the transmission of Chikungunya agreed to answer the survey...
June 2016: Revista de Salud Pública
https://www.readbyqxmd.com/read/28442298/how-to-study-and-overcome-tumor-heterogeneity-with-circulating-biomarkers-the-breast-cancer-case
#20
REVIEW
Valentina Appierto, Serena Di Cosimo, Carolina Reduzzi, Valentina Pala, Vera Cappelletti, Maria Grazia Daidone
Breast cancer ranks first among female cancer-related deaths in Western countries. As the primary tumor can often be controlled by surgical resection, the survival of women with breast cancer is closely linked to the incidence of distant metastases. Molecular screening by next generation sequencing highlighted the spatial and temporal heterogeneity of solid tumors as well as the clonal evolution of cancer cells during progression and under treatment pressure. Such findings question whether an optimal assessment of disease progression and a screening for druggable mutations should be based on molecular features of primary or recurrent/metastatic lesions and therefore represent a crucial element for failure or success of personalized medicine...
April 22, 2017: Seminars in Cancer Biology
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