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https://www.readbyqxmd.com/read/28888237/street-floods-in-metro-manila-and-possible-solutions
#1
Alfredo Mahar Lagmay, Jerico Mendoza, Fatima Cipriano, Patricia Anne Delmendo, Micah Nieves Lacsamana, Marc Anthony Moises, Nicanor Pellejera, Kenneth Niño Punay, Glenn Sabio, Laurize Santos, Jonathan Serrano, Herbert James Taniza, Neil Eneri Tingin
Urban floods from thunderstorms cause severe problems in Metro Manila due to road traffic. Using Light Detection and Ranging (LiDAR)-derived topography, flood simulations and anecdotal reports, the root of surface flood problems in Metro Manila is identified. Majority of flood-prone areas are along the intersection of creeks and streets located in topographic lows. When creeks overflow or when rapidly accumulated street flood does not drain fast enough to the nearest stream channel, the intersecting road also gets flooded...
September 2017: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/28768461/quantitative-analysis-of-impact-of-awareness-raising-activities-on-organic-solid-waste-separation-behaviour-in-balikpapan-city-indonesia
#2
Noriaki Murase, Takehiko Murayama, Shigeo Nishikizawa, Yuriko Sato
Many cities in Indonesia are under pressure to reduce solid waste and dispose of it properly. In response to this pressure, the Japan International Cooperation Agency and the Indonesian Government have implemented a solid waste separation and collection project to reduce solid waste in the target area (810 households) of Balikpapan City. We used a cluster randomised controlled trial method to measure the impact of awareness-raising activities that were introduced by the project on residents' organic solid waste separation behaviour...
August 1, 2017: Waste Management & Research
https://www.readbyqxmd.com/read/28260529/implementing-a-vector-surveillance-response-system-for-chagas-disease-control-a-4-year-field-trial-in-nicaragua
#3
Kota Yoshioka, Doribel Tercero, Byron Pérez, Jiro Nakamura, Lenin Pérez
BACKGROUND: Chagas disease is one of the neglected tropical diseases (NTDs). International goals for its control involve elimination of vector-borne transmission. Central American countries face challenges in establishing sustainable vector control programmes, since the main vector, Triatoma dimidiata, cannot be eliminated. In 2012, the Ministry of Health in Nicaragua started a field test of a vector surveillance-response system to control domestic vector infestation. This paper reports the main findings from this pilot study...
March 6, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/27884679/risk-stratified-staging-in-paediatric-hepatoblastoma-a-unified-analysis-from-the-children-s-hepatic-tumors-international-collaboration
#4
RANDOMIZED CONTROLLED TRIAL
Rebecka L Meyers, Rudolf Maibach, Eiso Hiyama, Beate Häberle, Mark Krailo, Arun Rangaswami, Daniel C Aronson, Marcio H Malogolowkin, Giorgio Perilongo, Dietrich von Schweinitz, Marc Ansari, Dolores Lopez-Terrada, Yukichi Tanaka, Rita Alaggio, Ivo Leuschner, Tomoro Hishiki, Irene Schmid, Kenichiro Watanabe, Kenichi Yoshimura, Yurong Feng, Eugenia Rinaldi, Davide Saraceno, Marisa Derosa, Piotr Czauderna
BACKGROUND: Comparative assessment of treatment results in paediatric hepatoblastoma trials has been hampered by small patient numbers and the use of multiple disparate staging systems by the four major trial groups. To address this challenge, we formed a global coalition, the Children's Hepatic tumors International Collaboration (CHIC), with the aim of creating a common approach to staging and risk stratification in this rare cancer. METHODS: The CHIC steering committee-consisting of leadership from the four major cooperative trial groups (the International Childhood Liver Tumours Strategy Group, Children's Oncology Group, the German Society for Paediatric Oncology and Haematology, and the Japanese Study Group for Paediatric Liver Tumours)-created a shared international database that includes comprehensive data from 1605 children treated in eight multicentre hepatoblastoma trials over 25 years...
January 2017: Lancet Oncology
https://www.readbyqxmd.com/read/27443209/an-update-discussion-on-the-current-assessment-of-the-safety-of-veterinary-antimicrobial-drug-residues-in-food-with-regard-to-their-impact-on-the-human-intestinal-microbiome
#5
Carl E Cerniglia, Silvia A Pineiro, Susan F Kotarski
The human gastrointestinal tract ecosystem consists of complex and diverse microbial communities that have now been collectively termed the intestinal microbiome. Recent scientific breakthroughs and research endeavours have increased our understanding of the important role the intestinal microbiome plays in human health and disease. The use of antimicrobial new animal drugs in food-producing animals may result in the presence of low levels of drug residues in edible foodstuffs. There is concern that antimicrobial new animal drugs in or on animal-derived food products at residue-level concentrations could disrupt the colonization barrier and/or modify the antimicrobial resistance profile of human intestinal bacteria...
May 2016: Drug Testing and Analysis
https://www.readbyqxmd.com/read/27303099/healthcare-in-myanmar
#6
REVIEW
Nyi Nyi Latt, Su Myat Cho, Nang Mie Mie Htun, Yu Mon Saw, Myat Noe Htin Aung Myint, Fumiko Aoki, Joshua A Reyer, Eiko Yamamoto, Yoshitoku Yoshida, Nobuyuki Hamajima
Myanmar transitioned to a civilian government in March, 2011. Although the democratic process has accelerated since then, many problems in the field of healthcare still exist. Since there is a limited overview on the healthcare in Myanmar, this article briefly describes the current states surrounding health services in Myanmar. According to the Census 2014, the population in the Republic of the Union of Myanmar was 51,410,000. The crude birth rate in the previous one year was estimated to be 18.9 per 1,000, giving the annual population growth rate of 0...
May 2016: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/26092283/cross-sectional-analysis-of-self-efficacy-and-social-capital-in-a-community-based-healthy-village-project-in-santa-cruz-bolivia
#7
Motoyuki Yuasa, Yoshihisa Shirayama, Keiichi Osato, Cesar Miranda, Julia Condore, Roxana Siles
BACKGROUND: An assessment of self-efficacy and social capital may have the potential to detect an effect of dynamic, complex and comprehensive collective actions in community-based health promotion. In 2003, a healthy village project was launched in Santa Cruz, Bolivia with technical assistance from the Japan International Cooperation Agency (JICA). The originally developed FORSA (Fortalecimiento de Redes de Salud) model accounted for participatory processes in which people could improve their health and well-being through individual behavioral changes and family/community-driven activities...
2015: BMC International Health and Human Rights
https://www.readbyqxmd.com/read/25892631/repeated-dose-liver-micronucleus-assay-using-clofibrate-in-young-adult-rats
#8
Tomomi Takayanagi, Rie Takashima, Yumi Wako, Kazufumi Kawasako, Yasuhiro Tanaka, Hisako Hori, Wataru Fujii
The repeated-dose liver micronucleus (MN) assay is a newly established in vivo genotoxicity test for evaluation of liver carcinogens. It may be integrated into general toxicity studies, thereby reducing the numbers of animals required for assessment of chemical safety. A collaborative study by the Mammalian Mutagenicity Study (MMS) Group further evaluated this assay using a wide range of chemicals, including carcinogens and non-carcinogens in young adult rats. In this study, we administered clofibrate (125, 250, or 500mg/kg/day) for 14 or 28 days, and examined the micronucleated (MNed) cell frequencies in the liver and bone marrow...
March 2015: Mutation Research. Genetic Toxicology and Environmental Mutagenesis
https://www.readbyqxmd.com/read/25730921/international-conference-on-harmonisation-s10-photosafety-evaluation-of-pharmaceuticals-guidance-for-industry-availability-notice
#9
(no author information available yet)
The Food and Drug Administration (FDA) is announcing the availability of a guidance for industry entitled "S10 Photosafety Evaluation of Pharmaceuticals.'' The guidance was prepared under the auspices of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). This guidance outlines details on when photosafety testing is warranted and on possible assessment strategies; it should be read in conjunction with the ICH M3(R2) guidance, section XIV(14) Photosafety Testing...
January 27, 2015: Federal Register
https://www.readbyqxmd.com/read/25707200/-accession-to-the-pic-s-and-pharmaceutical-quality-system-in-japan
#10
Noriko Katori
In March, 2012, Japan made the application for membership of the Pharmaceutical Inspection convention and Pharmaceutical Inspection Co-operation scheme (PIC/S) which is an international body of a GMP inspection. The globalization of pharmaceutical manufacturing and sales has been a driving force behind the decision to become a PIC/S member. For the application for membership, Japan's GMP inspectorate needs to fulfill PIC/S requirements, for example, the inspection organization has to have a quality system as a global standard...
2014: Kokuritsu Iyakuhin Shokuhin Eisei Kenkyūjo Hōkoku, Bulletin of National Institute of Health Sciences
https://www.readbyqxmd.com/read/25470465/enhancing-us-japan-cooperation-to-combat-antimicrobial-resistance
#11
C Sachi Gerbin
The Global Health Security Agenda (GHSA) is aimed at preventing, detecting, and responding to infectious disease threats. To move toward these goals, the United States has committed to partner with at least 30 countries around the world. One of the objectives of the GHSA includes "[p]reventing the emergence and spread of antimicrobial drug resistant organisms." Antimicrobial resistance (AMR) has become a growing global health security problem, with inappropriate use of antimicrobial medications in humans and animals and a lack of new antimicrobial medications contributing to this problem...
November 2014: Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science
https://www.readbyqxmd.com/read/25237279/capacity-building-toward-evidence-based-medicine-among-healthcare-professionals-at-the-university-of-medicine-and-pharmacy-ho-chi-minh-city-and-its-related-institutes
#12
LE Thi Quynh Nga, Aya Goto, Tran The Trung, Nguyen Quang Vinh, Nguyen Thy Khue
Research capacity development enhances a country's ownership of activities aimed at strengthening its health system. In Vietnam, continuing medical education (CME) is attracting increasing attention with the establishment of legal and policy frameworks. During 2010-2013, the Japan International Cooperation Agency funded a research capacity building project targeting physicians in Ho Chi Minh City. The project had been developed in four previous courses that were conducted in collaboration with Fukushima Medical University and Ho Chi Minh City University of Medicine and Pharmacy (UMP)...
February 1, 2014: Japan Medical Association Journal: JMAJ
https://www.readbyqxmd.com/read/24866782/steps-toward-harmonization-for-clinical-development-of-medicines-in-pediatric-ulcerative-colitis-a-global-scientific-discussion-part-2-data-extrapolation-trial-design-and-pharmacokinetics
#13
Haihao Sun, Richard Vesely, Robert M Nelson, Jan Taminiau, Peter Szitanyi, Maria Isaac, Agnes Klein, Shinobu Uzu, Donna Griebel, Andrew E Mulberg
OBJECTIVES: To facilitate global drug development, the International Pediatric Inflammatory Bowel Disease Working Group (i-IBD Working Group) discussed data extrapolation, trial design, and pharmacokinetic (PK) considerations for drugs intended to treat pediatric ulcerative colitis (UC), and considered possible approaches toward harmonized drug development. METHODS: Representatives from the US Food and Drug Administration, European Medicines Agency, Health Canada, and the Pharmaceuticals and Medical Devices Agency of Japan convened monthly to explore existing regulatory approaches, reviewed the results of a literature search, and provided perspectives on pediatric UC drug development based on the available medical literature...
June 2014: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/24866781/steps-toward-harmonization-for-clinical-development-of-medicines-in-pediatric-ulcerative-colitis-a-global-scientific-discussion-part-1-efficacy-endpoints-and-disease-outcome-assessments
#14
Haihao Sun, Richard Vesely, Jan Taminiau, Peter Szitanyi, Elektra J Papadopoulos, Maria Isaac, Agnes Klein, Shinobu Uzu, Donna Griebel, Andrew E Mulberg
OBJECTIVES: There is a pressing need for drug development in pediatric ulcerative colitis (UC). Lack of scientific consensus on efficacy endpoints and disease outcome assessments presents a hurdle for global drug development in pediatric UC. Scientists from 4 regulatory agencies convened an International Inflammatory Bowel Disease Working Group (i-IBD Working Group) to harmonize present thinking about various aspects of drug development in pediatric UC globally. METHODS: The i-IBD Working Group was convened in 2012 by scientists from the US Food and Drug Administration, European Medicines Agency, Health Canada, and the Pharmaceuticals and Medical Devices Agency of Japan...
June 2014: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/24835879/the-korea-national-research-resource-center
#15
Dongsin Lee, Yeonhee Lee
Research resources with associated information are the most essential materials in the study and application of the life sciences, since these are employed in everything from basic research to advanced industrial high technology. Numerous nations recognize the importance of these scientific assets and are simultaneously enhancing their internal security measures and strengthening international cooperation to protect and share them. Consequently, most resource centers are sustained by governments under various national strategic plans...
September 2009: Biopreservation and Biobanking
https://www.readbyqxmd.com/read/24769582/-two-research-projects-on-infectious-diseases-conducted-in-noguchi-memorial-institute-for-medical-research-university-of-ghana-by-tokyo-medical-and-dental-university
#16
Eiji Ido, Shoji Yamaoka
Ghana-Tokyo Medical and Dental University Research Collaboration Center has been established since 2008 when our Program was chosen together with the Program in the Philippines proposed by Tohoku University as an additional small-scale research center of the Overseas Research Program on Emerging and Reemerging Diseases that is funded by the Ministry of Education, Culture, Sports, Science and Technology of the Japanese Government and started in 2005. This 5-year government-supported Program has changed its name to develop into a more active world-level program called Japan Initiative for Global Research Network on Infectious Diseases (J-GRID) and entered the second 5-year phase in 2010, and our Program is playing an important role among other research centers located in Asia and Africa...
2013: Uirusu
https://www.readbyqxmd.com/read/24769579/-research-activities-in-kobe-indonesia-collaborative-research-centers
#17
Takako Utsumi, Yoshitake Hayashi, Hak Hotta
Kobe-Indonesia Collaborative Research Center was established in Institute of Tropical Disease (ITD), Airlangga University, Surabaya, Indonesia in 2007 under the program of ''Founding Research Centers for Emerging and Reemerging Infectious Diseases'' supported by the Ministry of Education, Culture, Sports, Science and Technology, Japan, and then it has been under the Japan Initiative for Global Research Network on Infectious Diseases (J-GRID) since 2010. Japanese researchers have been stationed at ITD, conducting joint researches on influenza, viral hepatitis, dengue and infectious diarrhea...
2013: Uirusu
https://www.readbyqxmd.com/read/24769578/-j-grid-and-satreps-programs-in-thailand
#18
Masanori Kameoka, Tadahiro Sasaki
Thailand-Japan Research Collaboration Center on Emerging and Re-emerging Infections (RCC-ERI) was established in 2005 as a research collaboration center cooperated by Research Institute for Microbial Diseases (RIMD), Osaka University and Department of Medical Sciences, Ministry of Public Health of Thailand. In addition, Mahidol-Osaka Center for Infectious Diseases (MOCID) was established in 2010, also as another research collaboration center cooperated by RIMD, Osaka University and Faculty of Tropical Medicine, Mahidol University...
2013: Uirusu
https://www.readbyqxmd.com/read/24340671/-ion-pair-hplc-analysis-of-b-vitamins-in-syrup-products-in-indonesia
#19
Tamaki Miyazaki, Tadafumi Horisaki, Yukio Aso, Haruhiro Okuda
A training course for analysis of B vitamins in syrup products was undertaken at the National Agency of Drug and Food Control at Jakarta as part of the project to deliver safe drugs to people in Indonesia by Japan International Cooperation Agency. Analytical methods have been developed for quantitative determination of B vitamins by ion-pair high-performance liquid chromatography using 1-hexanesulfonic acid sodium salt. Measurements were performed for two syrup products removed from a drug store in Jakarta to determine the amount of each vitamin B...
2013: Kokuritsu Iyakuhin Shokuhin Eisei Kenkyūjo Hōkoku, Bulletin of National Institute of Health Sciences
https://www.readbyqxmd.com/read/24053583/contribution-of-the-japan-international-cooperation-agency-health-related-projects-to-health-system-strengthening
#20
Motoyuki Yuasa, Yoshie Yamaguchi, Mihoko Imada
BACKGROUND: The Japan International Cooperation Agency (JICA) has focused its attention on appraising health development assistance projects and redirecting efforts towards health system strengthening. This study aimed to describe the type of project and targets of interest, and assess the contribution of JICA health-related projects to strengthening health systems worldwide. METHODS: We collected a web-based Project Design Matrix (PDM) of 105 JICA projects implemented between January 2005 and December 2009...
2013: BMC International Health and Human Rights
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