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https://www.readbyqxmd.com/read/29196471/first-person-lai-kuan-dionne-and-eric-peterman
#1
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First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Lai Kuan Dionne and Eric Peterman are co-first authors on 'FYCO1 regulates accumulation of post-mitotic midbodies by mediating LC3-dependent midbody degradation', published in Journal of Cell Science. Lai Kuan Dionne is a post-doctoral associate in the lab of Moe Mahjoub at Washington University School of Medicine, investigating the molecular mechanisms of post-mitotic midbody accumulation and secretion in health and diseases...
December 1, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/29177894/understanding-the-factors-that-influence-perceptions-of-post-wildfire-landscape-recovery-across-25-wildfires-in-the-northwestern-united-states
#2
C Kooistra, T E Hall, T Paveglio, M Pickering
Disturbances such as wildfire are important features of forested landscapes. The trajectory of changes following wildfires (often referred to as landscape recovery) continues to be an important research topic among ecologists and wildfire scientists. However, the landscape recovery process also has important social dimensions that may or may not correspond to ecological or biophysical perspectives. Perceptions of landscape recovery may affect people's attitudes and behaviors related to forest and wildfire management...
November 25, 2017: Environmental Management
https://www.readbyqxmd.com/read/29172860/washington-state-spirits-privatization-how-satisfied-were-liquor-purchasers-before-and-after-and-by-type-of-retail-store-in-2014
#3
Thomas K Greenfield, Edwina Williams, William C Kerr, Meenakshi S Subbaraman, Yu Ye
BACKGROUND: In 2012 Washington State ended a wholesale/retail monopoly on liquor, permitting sale of spirits in stores with > 10,000 square feet. Implementation resulted in average price increases, but also five times the stores selling liquor. OBJECTIVES: As part of a privatization evaluation, we studied pre-post and between-store-type purchase experiences. METHODS: A 2010 Washington State Liquor Control Board (LCB) survey of liquor purchasers (n = 599), and the 2014 baseline of a repeated telephone survey (1,202 residents; n = 465 purchasers), each included 10 LCB questions on satisfaction with purchase experiences, each attribute with graded response scale A = 4 to D = 1 and F (0 = fail)...
November 27, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/29162847/clinical-and-immunopathological-findings-during-long-term-follow-up-in-leishmania-infantum-experimentally-infected-dogs
#4
Melissa Moura Costa Abbehusen, Valter Dos Anjos Almeida, Manuela da S Solcà, Laís da Silva Pereira, Dirceu Joaquim Costa, Leonardo Gil-Santana, Patricia Torres Bozza, Deborah Bittencourt Moté Fraga, Patrícia Sampaio Tavares Veras, Washington Luis Conrado Dos-Santos, Bruno Bezerril Andrade, Claudia Ida Brodskyn
Canine Visceral Leishmaniasis (CVL) is caused by Leishmania infantum, which in the New World is transmitted by Lutzomyia longipalpis. While prospective clinical and immunological assessments of dogs experimentally challenged with L. infantum have been previously reported over a relatively short follow-up period, the long-term characterization of infected animals has not been performed to date. We evaluated dogs in a subclinical state for six years following experimental infection with L. infantum and Lu. longipalpis saliva, via an intradermal route, to characterize clinical, parasitological and immunological parameters arising from L...
November 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29153941/the-impact-of-readmission-hospital-on-failure-to-rescue-rates-following-major-urologic-cancer-surgery
#5
Jasmir G Nayak, Sarah K Holt, Jonathan L Wright, Matthew Mossanen, Atreya Dash, John L Gore
PURPOSE: Patients readmitted to secondary hospitals rather than the primary hospital where their surgery took place may be at risk for poorer outcomes. We sought to evaluate the effect of site of readmission on failure-to-rescue complication rates following urologic cancer surgery. MATERIALS AND METHODS: Retrospective review of major urologic cancer surgeries in the Washington State Comprehensive Hospital Abstract Reporting System between 1998 and 2013. Failure-to-rescue (FTR) rates, defined as inpatient death after a complication requiring hospital readmission, were compared between patients readmitted to their primary hospital with those readmitted to a secondary hospital...
November 16, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/29150316/low-threshold-extended-release-naltrexone-for-high-utilizers-of-public-services-with-severe-alcohol-use-disorder-a-pilot-study
#6
Shannon Smith-Bernardin, Chris Rowe, Emily Behar, Michelle Geier, Stuart Washington, Glenn-Milo Santos, Jason Euren, Judith Martin, Alice Gleghorn, Phillip O Coffin
Extended-release naltrexone (XRNTX) is an effective treatment for alcohol use disorder (AUD). We sought to evaluate the feasibility, acceptability, and preliminary effectiveness and cost-effectiveness of XRNTX delivered as a stand-alone service to persons with severe AUD who are high utilizers of multiple urgent and emergency medical services (HUMS). Of 15 HUMS persons with severe AUD selected based on chart review, 11 agreed to participate. Participants received a mean of 4.5 injections (range 2-7). Modest benefits from XRNTX were observed in terms of patients' Urge-to-Drink Score and the costs of emergency medical services utilized...
November 8, 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/29132999/radiologists-and-social-media-do-not-forget-about-facebook
#7
Rebecca L Seidel, Aryan Jalilvand, Jean Kunjummen, Lea Gilliland, Richard Duszak
PURPOSE: Facebook (Facebook, Inc, Menlo Park, California, USA) is the most popular social networking platform worldwide. Facebook groups are virtual communities of people who share a common interest. Breast Imaging Radiologists is a Facebook group for radiologists with an interest in breast imaging. The purpose of this study was to analyze the membership and activity of the Breast Imaging Radiologists Facebook group (BIRFG) for 2 years since its inception. METHODS: Using both the Grytics (www...
November 11, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29127114/compared-with-what-estimating-the-effects-of-injury-prevention-policies-using-the-synthetic-control-method
#8
Carl Bonander
INTRODUCTION: This paper discusses the application of the synthetic control method to injury-related interventions using aggregate data from public information systems. The method selects and determines the optimal control unit in the data by minimising the difference between the pre-intervention outcomes in one treated unit (eg, a state) and a weighted combination of potential control units. METHOD: I demonstrate the synthetic control method by an application to Florida's post-2010 policy and law enforcement initiatives aimed at bringing down opioid overdose deaths...
November 10, 2017: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
https://www.readbyqxmd.com/read/29122180/associations-between-heat-exposure-vigilance-and-balance-performance-in-summer-tree-fruit-harvesters
#9
June T Spector, Jennifer Krenz, Miriam Calkins, Dawn Ryan, Jose Carmona, Mengjie Pan, Anna Zemke, Paul D Sampson
BACKGROUND: We sought to evaluate potential mediators of the relationship between heat exposure and traumatic injuries in outdoor agricultural workers. METHODS: Linear mixed models were used to estimate associations between maximum work-shift Wet Bulb Globe Temperature (WBGTmax) and post-shift vigilance (reaction time) and postural sway (total path length) in a cross-sectional sample of 46 Washington State tree fruit harvesters in August-September 2015. RESULTS: The mean (SD) WBGTmax was 27...
February 2018: Applied Ergonomics
https://www.readbyqxmd.com/read/29101547/oral-pregabalin-for-acute-pain-relief-after-cervicofacial-surgery-a-systematic-review
#10
REVIEW
Sara Liébana-Hermoso, Francisco Javier Manzano-Moreno, Manuel Francisco Vallecillo-Capilla, Maria Victoria Olmedo-Gaya
OBJECTIVE: The objectives of this systematic review were to unify criteria on the effectiveness of oral pregabalin to treat acute post-operative pain after cervicofacial surgery, to establish the most effective dose regimens, and to determine its effect on rescue medicine consumption and its association with adverse effects. MATERIALS AND METHODS: PubMed/Medline (National Library of Medicine, Washington, DC), Scopus, Web of Science, and Cochrane databases were searched for studies in any language published between January 2000 and September 2016...
November 3, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29033802/the-neurobiological-mechanism-of-chemical-aversion-emetic-therapy-for-alcohol-use-disorder-an-fmri-study
#11
Ralph L Elkins, Todd L Richards, Robert Nielsen, Richard Repass, Henriettae Stahlbrandt, Hunter G Hoffman
A recent NIH epidemiology study found the lifetime prevalence of alcohol use disorder in the United States to be 29%. Alcohol drinking behavior is strongly "learned" via pleasure center activation/reinforcement. Alcohol craving is a powerful desire to drink alcoholic beverages. Craving was added as one of the defining criteria for alcohol use disorder in DSM5, and craving reduction is becoming an increasingly important treatment goal. In the current study, patients with alcohol use disorder received 10 days of inpatient multi-modal treatments at Schick Shadel Hospital (SSH) of Seattle...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/29030020/the-trajectory-of-positive-psychological-change-in-a-head-and-neck-cancer-population
#12
S A Harding
A stressful event may be sufficient to challenge a strongly held set of assumptions about the world and the self. In some people this may lead to post-traumatic stress disorder (PTSD) and in others to positive psychological change (PPC), whereby a person's reactions to the challenge are beneficial. Little research has investigated PPC in people who have had head and neck cancer (HNC). The aim of this study was to identify demographic, clinical, and psychological factors associated with PPC over time. A cross-sequential study collected data over 5 years...
October 10, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28967447/comfort%C3%A2-sm-communication-for-oncology-nurses-program-overview-and-preliminary-evaluation-of-a-nationwide-train-the-trainer-course
#13
Elaine Wittenberg, Betty Ferrell, Joy Goldsmith, Sandra L Ragan, Haley Buller
OBJECTIVE: The COMFORT Communication Course for Oncology Nurses is a train-the-trainer program funded by the National Cancer Institute (R25) that provides nationwide communication training to improve patient-centered communication in cancer care. The purpose of this article is to provide an overview of the program and present an evaluation of three courses. METHODS: The curriculum contains seven modules addressing palliative care communication. Pre-course survey of needs, post-course feedback, and follow-up at 6 and 12 months were used to evaluate the program...
September 22, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28943022/patient-reported-quality-of-life-outcomes-following-treatment-for-oral-cancer
#14
J Breeze, A Rennie, D Dawson, J Tipper, K-U Rehman, N Grew, N Pigadas
Patient-reported quality of life (QoL) outcomes have the potential to assist clinicians in providing individually tailored treatment decisions. QoL assessments were collected prospectively for 168 consecutive patients treated for oral cancer between 1 January 2010 and 31 December 2014 using the University of Washington Quality of Life Questionnaire. Patients were followed up for 18 months post-treatment. Sub-group analyses were performed using paired t-tests and analysis of variance (ANOVA) to compare the effects of adjunctive chemoradiotherapy, type of bone resection, and methods of soft and hard tissue flap reconstruction...
September 21, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28926727/early-pregnancy-intrauterine-fetal-exposure-to-maternal-smoking-and-impact-on-fetal-telomere-length
#15
Hooman Mirzakhani, Immaculata De Vivo, J Steven Leeder, Roger Gaedigk, Carrie A Vyhlidal, Scott T Weiss, Kelan Tantisira
BACKGROUND: Reduced telomere length, or its accelerated attrition, has been implicated in aging, mortality, and several human diseases, including respiratory diseases. Age dependent manifestation of telomere-mediated disease during life span indicates the role of developmental stage in these diseases and highlights the importance of fetal developmental process in utero and at earlier life stages. Environmental determinants during developmental and later stages of life could affect telomere length...
November 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28886257/prevalence-and-causes-of-visual-impairment-in-fundong-district-north-west-cameroon-results-of-a-population-based-survey
#16
Joseph Oye, Islay Mactaggart, Sarah Polack, Elena Schmidt, Violet Tamo, Marvice Okwen, Hannah Kuper
PURPOSE: To estimate the prevalence and causes of visual impairment in Fundong Health District, North West Cameroon. METHODS: A total of 51 clusters of 80 people (all ages) were sampled with probability proportionate to size and compact segment sampling. Visual acuity (VA) was measured with a tumbling "E" chart. An ophthalmic nurse examined people with VA<6/18 in either eye. The presence of hearing and physical impairments were assessed using clinical examination, and self-reported visual problems using the Washington Group Short Set...
September 8, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28885557/evaluation-of-a-pilot-implementation-to-integrate-alcohol-related-care-within-primary-care
#17
Jennifer F Bobb, Amy K Lee, Gwen T Lapham, Malia Oliver, Evette Ludman, Carol Achtmeyer, Rebecca Parrish, Ryan M Caldeiro, Paula Lozano, Julie E Richards, Katharine A Bradley
Alcohol use is a major cause of disability and death worldwide. To improve prevention and treatment addressing unhealthy alcohol use, experts recommend that alcohol-related care be integrated into primary care (PC). However, few healthcare systems do so. To address this gap, implementation researchers and clinical leaders at Kaiser Permanente Washington partnered to design a high-quality Program of Sustained Patient-centered Alcohol-related Care (SPARC). Here, we describe the SPARC pilot implementation, evaluate its effectiveness within three large pilot sites, and describe the qualitative findings on barriers and facilitators...
September 8, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28845591/mitochondrial-degeneration-precedes-the-development-of-muscle-atrophy-in-progression-of-cancer-cachexia-in-tumour-bearing-mice
#18
Jacob L Brown, Megan E Rosa-Caldwell, David E Lee, Thomas A Blackwell, Lemuel A Brown, Richard A Perry, Wesley S Haynie, Justin P Hardee, James A Carson, Michael P Wiggs, Tyrone A Washington, Nicholas P Greene
BACKGROUND: Cancer cachexia is largely irreversible, at least via nutritional means, and responsible for 20-40% of cancer-related deaths. Therefore, preventive measures are of primary importance; however, little is known about muscle perturbations prior to onset of cachexia. Cancer cachexia is associated with mitochondrial degeneration; yet, it remains to be determined if mitochondrial degeneration precedes muscle wasting in cancer cachexia. Therefore, our purpose was to determine if mitochondrial degeneration precedes cancer-induced muscle wasting in tumour-bearing mice...
August 28, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28827206/relationship-between-gonadal-function-and-cardiometabolic-risk-in-young-men-with-chronic-spinal-cord-injury
#19
Shannon D Sullivan, Mark S Nash, Eshetu Tefara, Emily Tinsley, Suzanne Groah
BACKGROUND: We reported previously that young men with chronic spinal cord injury (SCI) have a greater prevalence of testosterone deficiency compared with an age-matched, healthy control population. Young men with SCI also are at increased risk for developing cardiometabolic dysfunction after injury. It is unclear whether testosterone deficiency is associated with heightened cardiometabolic risk in men with SCI. OBJECTIVE: To investigate associations among levels of testosterone in young men with chronic SCI and surrogate markers of cardiometabolic risk...
August 18, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28817335/killed-by-police-validity-of-media-based-data-and-misclassification-of-death-certificates-in-massachusetts-2004-2016
#20
Justin M Feldman, Sofia Gruskin, Brent A Coull, Nancy Krieger
OBJECTIVES: To assess the validity of demographic data reported in news media-based data sets for persons killed by police in Massachusetts (2004-2016) and to evaluate misclassification of these deaths in vital statistics mortality data. METHODS: We identified 84 deaths resulting from police intervention in 4 news media-based data sources (WGBH News, Fatal Encounters, The Guardian, and The Washington Post) and, via record linkage, conducted matched-pair analyses with the Massachusetts mortality data...
October 2017: American Journal of Public Health
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