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Marian L Neuhouser, Ashley Wilder Smith, Stephanie M George, James T Gibson, Kathy B Baumgartner, Richard Baumgartner, Catherine Duggan, Leslie Bernstein, Anne McTiernan, Rachel Ballard
PURPOSE: Use of complementary and alternative medicine (CAM) is common among breast cancer patients, but less is known about whether CAM influences breast cancer survival. METHODS: Health Eating, Activity, and Lifestyle (HEAL) Study participants (n = 707) were diagnosed with stage I-IIIA breast cancer. Participants completed a 30-month post-diagnosis interview including questions on CAM use (natural products such as dietary and botanical supplements, alternative health practices, and alternative medical systems), weight, physical activity, and comorbidities...
October 21, 2016: Breast Cancer Research and Treatment
Amber C Beckett, M Blanca Piazuelo, Jennifer M Noto, Richard M Peek, M Kay Washington, Holly M Scott Algood, Timothy L Cover
Epidemiologic studies have provided conflicting data regarding an association between H. pylori infection and iron deficiency anemia (IDA) in humans. Here, a Mongolian gerbil model was used to investigate a potential role of H. pylori infection, as well as a possible role of diet, in H. pylori-associated IDA. Mongolian gerbils (either H. pylori-infected or uninfected) received a normal diet or one of three diets associated with increased H. pylori virulence: high salt, low iron, or combination high salt/low iron...
September 12, 2016: Infection and Immunity
Levent Özgönenel, Sultan Çağırıcı, Murat Çabalar, Gülis Durmuşoğlu
BACKGROUND: Parkinson's disease (PD) predisposes to falls due to postural instability and decreased coordination. Postural and coordination exercises could ameliorate the incoordination and decrease falls. AIMS: In this study, we explored the efficiency of a game console as an adjunct to an exercise program in treating incoordination in patients with PD. STUDY DESIGN: Case-control study. METHODS: In this single-blind, prospective clinical trial, rehabilitation with the Xbox (Microsoft; Washington, USA) game console was used as an adjunct to a standard rehabilitation program...
July 2016: Balkan Medical Journal
Saro H Armenian, Wassim Chemaitilly, Marcus Chen, Eric J Chow, Christine N Duncan, Lee W Jones, Michael A Pulsipher, Alan T Remaley, Alicia Rovo, Nina Salooja, Minoo Battiwalla
A number of studies have shown that autologous and allogeneic hematopoietic cell transplantation (HCT) contribute to an increased incidence of cardiovascular disease (CVD) and worsening of cardiovascular risk factors that could contribute to further CVD over time. These observations, combined with a notable increase in the number of survivors after HCT in recent years, highlight the need for studies aimed at modifying risk or preventing these outcomes by changing specific approaches and/or post-HCT interventions...
August 30, 2016: Biology of Blood and Marrow Transplantation
Kathleen R Bell, Jesse R Fann, Jo Ann Brockway, Wesley R Cole, Nigel E Bush, Sureyya Dikmen, Tessa Hart, Ariel J Lang, Gerald Grant, Gregory Gahm, Mark A Reger, Jef St De Lore, Joan Machamer, Karin Ernstrom, Rema Raman, Sonia Jain, Murray B Stein, Nancy Temkin
Mild traumatic brain injury (mTBI) is a common injury for service members in recent military conflicts. There is insufficient evidence of how best to treat the consequences of mTBI. In a randomized, clinical trial, we evaluated the efficacy of telephone-delivered problem-solving treatment (PST) on psychological and physical symptoms in 356 post-deployment active duty service members from Joint Base Lewis McChord, Washington, and Fort Bragg, North Carolina. Members with medically confirmed mTBI sustained during deployment to Iraq and Afghanistan within the previous 24 months received PST or education-only (EO) interventions...
October 13, 2016: Journal of Neurotrauma
Meg H Zeller, Gia A Washington, James E Mitchell, David B Sarwer, Jennifer Reiter-Purtill, Todd M Jenkins, Anita P Courcoulas, James L Peugh, Marc P Michalsky, Thomas H Inge
BACKGROUND: Problematic alcohol use and increased sensitivity postoperatively in adult weight loss surgery patients heightens concerns. No data have characterized these behaviors in adolescents-a gap, given adolescent alcohol use and heavy drinking are public health concerns. OBJECTIVE: To examine alcohol use behavior in adolescents who underwent weight loss surgery across the first two post-operative years in comparison to nonsurgical adolescents. SETTING: Five academic medical centers...
May 25, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
Dan Cherkin, Benjamin Balderson, Georgie Brewer, Andrea Cook, Katherine Talbert Estlin, Sarah C Evers, Nadine E Foster, Jonathan C Hill, Rene Hawkes, Clarissa Hsu, Mark Jensen, Anne-Marie LaPorte, Martin D Levine, Diane Piekara, Pam Rock, Karen Sherman, Gail Sowden, Rob Wellman, John Yeoman
BACKGROUND: Despite numerous options for treating back pain and the increasing healthcare resources devoted to this problem, the prevalence and impact of back pain-related disability has not improved. It is now recognized that psychosocial factors, as well as physical factors, are important predictors of poor outcomes for back pain. A promising new approach that matches treatments to the physical and psychosocial obstacles to recovery, the STarT Back risk stratification approach, improved patients' physical function while reducing costs of care in the United Kingdom (UK)...
2016: BMC Musculoskeletal Disorders
Geetanjoli Banerjee, E Jennifer Edelman, Declan T Barry, William C Becker, Magdalena Cerdá, Stephen Crystal, Julie R Gaither, Adam J Gordon, Kirsha S Gordon, Robert D Kerns, Silvia S Martins, David A Fiellin, Brandon D L Marshall
AIMS: To estimate the influence of non-medical use of prescription opioids (NMUPO) on heroin initiation among US veterans receiving medical care. DESIGN: Using a multivariable Cox regression model, we analyzed data from a prospective, multi-site, observational study of HIV-infected and an age/race/site-matched control group of HIV-uninfected veterans in care in the United States. Approximately annual behavioral assessments were conducted and contained self-reported measures of NMUPO and heroin use...
November 2016: Addiction
Harsha Koneru, Robyn Cyr, Li Rebekah Feng, Edward Bae, Malika T Danner, Marilyn Ayoob, Thomas M Yung, Siyuan Lei, Brian T Collins, Leorey Saligan, Suy Simeng, Deepak Kumar, Sean P Collins
OBJECTIVES: The relationship between obesity (Body Mass Index ->30 kg/m(2)) and quality of life (QoL) following prostate cancer (PCa) radiation therapy (RT) is unknown. Excess abdominal fat may compromise the precise delivery of radiation, putting surrounding organs at risk for greater radiation exposure. Stereotactic body radiation therapy (SBRT) utilizes a real-time tracking system that provides updated prostate position information and allows for correction of the therapeutic beam during treatment with high accuracy...
2016: Curēus
Julia E Hood, Susan E Buskin, Bridget J Anderson, Alexandra Gagner, Jennifer Kienzle, David Maggio, Katie Markey, Jennifer Reuer, Nanette Benbow, Pascale Wortley
The impact of the Affordable Care Act (ACA) on HIV care patients, aged 18-64, was evaluated in three jurisdictions with Medicaid expansion (Chicago, New York State, and Washington) and three jurisdictions without Medicaid expansion (Georgia, Texas, and Virginia) using data from the Medical Monitoring Project. Multivariate regression models were used to evaluate insurance status that was reported pre- and post-ACA; self-reported impact of ACA on HIV care was explored with descriptive statistics. The likelihood of having insurance was significantly greater post-ACA compared to pre-ACA in Chicago (aRR = 1...
August 23, 2016: AIDS Care
Mary E Anderson, Jeffrey J Glasheen, Debra Anoff, Read Pierce, Molly Lane, Christine D Jones
BACKGROUND: Medicaid is often associated with longer hospitalizations and higher in-hospital mortality than other insurance types. OBJECTIVE: To characterize the impact of state Medicaid expansion status under the Affordable Care Act (ACA) on payer mix, length of stay (LOS), and in-hospital mortality. DESIGN/SETTING/PATIENTS: Retrospective cohort study of general medicine patients discharged from academic medical centers (AMCs) within the University HealthSystem Consortium from October 1, 2012 to September 30, 2015...
August 18, 2016: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
Gail Reed
After leaving Chile during the Pinochet era, Dr Morales studied economics, health administration and international health at the University of Montreal. But his baptism in the field came in Haiti, where he was first PAHO advisor to the health ministry, and then for five years was responsible for human resources and health economics in the PAHO offices in the capital of Port-au-Prince. He was at his post during the flooding in Gonaïves, five hurricanes, the 2010 earthquake and the ensuing cholera epidemic-doubtless the most dramatic and complex times for the country's health in recent history...
July 2016: MEDICC Review
S A Cohen, M C Woodfield, N Boyle, Z Stednick, M Boeckh, S A Pergam
BACKGROUND: Probiotic supplementation has been promoted for numerous health conditions; however, safety in immunosuppressed patients is unknown. We evaluated bloodstream infections (BSIs) caused by common probiotic organisms in hematopoietic cell transplant recipients. METHODS: All blood culture (BC) results from a cohort of hematopoietic cell transplant recipients transplanted at Fred Hutchinson Cancer Research Center in Seattle, Washington, between 2002 and 2011 were reviewed...
October 2016: Transplant Infectious Disease: An Official Journal of the Transplantation Society
Radica Z Alicic, Robert A Short, Cynthia L Corbett, Joshua J Neumiller, Brian J Gates, Kenn B Daratha, Celestina Barbosa-Leiker, Sterling McPherson, Naomi S Chaytor, Brad P Dieter, Stephen M Setter, Katherine R Tuttle
BACKGROUND: The hospital readmission rate in the population with chronic kidney disease (CKD) is high and strategies to reduce this risk are urgently needed. METHODS: The CKD-Medication Intervention Trial (CKD-MIT;; NCTO1459770) is a single-blind (investigators), randomized, clinical trial conducted at Providence Health Care in Spokane, Washington. Study participants are hospitalized patients with CKD stages 3-5 (not treated with kidney replacement therapy) and acute illness...
2016: American Journal of Nephrology
Chelakkot G Prameela, Rahul Ravind, P S Renil Mon, V S Sheejamol, M Dinesh
CONTEXT: Radiotherapy techniques have improved over years but have also raised concerns over subsequent acute and late effects. One such complication, dysphagia, has led to much interest and optimization in treatment delivery. AIMS: The aim of this study was to compare radiation dose to dysphagia aspiration related structures (DARS) in intensity modulated radiation therapy (IMRT) and three-dimensional conformal radiotherapy (3DCRT), and assess its relation to post-treatment swallowing status, in patients of carcinoma of the anterior two thirds of tongue...
April 2016: Journal of Cancer Research and Therapeutics
Wayne B Jonas, Dawn M Bellanti, Charmagne F Paat, Courtney C Boyd, Alaine Duncan, Ashley Price, Weimin Zhang, Louis M French, Heechin Chae
Background: Headaches are prevalent among Service members with traumatic brain injury (TBI); 80% report chronic or recurrent headache. Evidence for nonpharmacologic treatments, such as acupuncture, are needed. Objective: The aim of this research was to determine if two types of acupuncture (auricular acupuncture [AA] and traditional Chinese acupuncture [TCA]) were feasible and more effective than usual care (UC) alone for TBI-related headache. Materials and Methods: Design: This was a three-armed, parallel, randomized exploratory study...
June 1, 2016: Medical Acupuncture
Stephanie Helmus, Jauchia Blythe, Peter Guevara, Michael A Washington
Waterborne infection is an important cause of morbidity and mortality throughout the world. Personal hydration packs have been used by military personnel since the Gulf War and are now a common issue item. Since military personnel tend to operate under austere conditions and may use a variety of water sources, preventing the acquisition of waterborne infections is extremely important. Further, since hydration pack water reservoir replacements may not be available during combat operations, the development of a reliable cleaning protocol for use in the field is essential...
2016: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
Marisa M Silveri
The unpredictable and sometimes incomprehensible moods and behaviors of a teenager can be a head-scratching mystery-especially to parents. Hormones, boredom, social media, peer pressure, and drugs and alcohol are just a few of the factors to consider. Frances E. Jensen, M.D., professor and chair of neurology at the University of Pennsylvania and the mother of two sons who are now in their twenties (along with Washington Post health and science reporter and Pulitzer Prize winner Amy Ellis Nutt) look at the emerging science of the adolescent brain and provide advice based on Jensen's own research and experience as a single mother...
November 2015: Cerebrum: the Dana Forum on Brain Science
Richard A Perry, Lemuel A Brown, David E Lee, Jacob L Brown, Jamie I Baum, Nicholas P Greene, Tyrone A Washington
Aging decreases the ability of skeletal muscle to respond to injury. Leucine has been demonstrated to target protein synthetic pathways in skeletal muscle thereby enhancing this response. However, the effect of aging on leucine-induced alterations in protein synthesis at the onset of skeletal muscle regeneration has not been fully elucidated. The purpose of this study was to determine if aging alters skeletal muscle regeneration and leucine-induced alterations in markers of protein synthesis. The tibialis anterior of young (3 months) and aged (24 months) female C57BL/6J mice were injected with either bupivacaine or PBS, and the mice were given ad libitum access to leucine-supplemented or normal drinking water...
July 2016: Mechanisms of Ageing and Development
Stephanie Alessi Kraft, Mildred K Cho, Melissa Constantine, Sandra Soo-Jin Lee, Maureen Kelley, Diane Korngiebel, Cyan James, Ellen Kuwana, Adrienne Meyer, Kathryn Porter, Douglas Diekema, Alexander M Capron, Radica Alicic, Benjamin S Wilfond, David Magnus
BACKGROUND/AIMS: In the context of research on medical practices, which includes comparative effectiveness research and pragmatic clinical trials, empirical studies have begun to raise questions about the extent to which institutional review boards' interpretations and applications of research regulations align with patients' values. To better understand the similarities and differences between these stakeholder groups, we compare and contrast two surveys: one of institutional review board professionals and one of patients, which examine views on consent for research on medical practices...
October 2016: Clinical Trials: Journal of the Society for Clinical Trials
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