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https://www.readbyqxmd.com/read/28290941/professional-stress-and-burnout-in-u-s-military-medical-personnel-deployed-to-afghanistan
#1
Amy B Adler, Amanda L Adrian, Marla Hemphill, Nicole H Scaro, Maurice L Sipos, Jeffrey L Thomas
BACKGROUND: Studies of medical staff members have consistently documented high levels of burnout compared to those in other professions. Although there are studies of burnout in military medical staff, there are gaps in understanding the experience of medical staff while they are deployed and few occupationally-related factors associated with decreased burnout have been identified in this population. PURPOSE: To assess work-related variables accounting for burnout over and above rank, post-traumatic stress disorder (PTSD) symptoms, and professional stressors in the deployed environment...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28270346/molecular-and-hematologic-relapses-in-adult-patients-with-acute-promyelocytic-leukemia-a-cohort-study
#2
Ilana de França Azevedo, Michelline Gomes Magalhães, Fernanda Ribeiro Souto, Washington Batista das Neves, Fárida Coeli de Barros Correia Melo, Eduardo Magalhães Rego, Raul Antônio Morais Melo
OBJECTIVE: To evaluate factors predictive for relapse in a cohort of adult patients with acute promyelocytic leukemia monitored by molecular methods during consolidation and during at least one month of maintenance therapy. METHODS: The charts and laboratory data of 65 adult patients with acute promyelocytic leukemia treated according to the International Consortium on Acute Promyelocytic Leukemia 2006 protocol were reviewed. The identification of the promyelocytic leukemia-retinoic acid receptor-alpha gene rearrangement at diagnosis, post-induction, post-consolidation and during maintenance treatment was performed by qualitative and quantitative reverse transcription polymerase chain reaction...
January 2017: Revista Brasileira de Hematologia e Hemoterapia
https://www.readbyqxmd.com/read/28266137/development-of-groundwater-pesticide-exposure-modeling-scenarios-for-vulnerable-spring-and-winter-wheat-growing-areas
#3
Lauren Padilla, Michael Winchell, Natalia Peranginangin, Shanique Grant
Wheat crops and the major wheat-growing regions of the US are not included in the six crop and region specific scenarios developed by the Environmental Protection Agency (USEPA) for exposure modeling with the Pesticide Root Zone Model conceptualized for groundwater (PRZM-GW). This work augments the current scenarios by defining appropriately vulnerable PRZM-GW scenarios for high-producing spring and winter wheat growing regions that are appropriate for use in refined pesticide exposure assessments. Initial screening-level modeling was conducted for all wheat areas across the conterminous US as defined by multiple years of the Cropland Data Layer land use dataset...
March 7, 2017: Integrated Environmental Assessment and Management
https://www.readbyqxmd.com/read/28258704/nafld-phosphoproteomics-a-functional-piece-of-the-precision-puzzle
#4
Julia Wattacheril, Kristie L Rose, Salisha Hill, Christian Lanciault, Clark R Murray, Kay Washington, Brandon Williams, Wayne English, Matthew Spann, Ronald Clements, Naji Abumrad, Charles Robb Flynn
Molecular signaling events associated with the necroinflammatory changes in nonalcoholic steatohepatitis are not well understood. To understand the molecular basis of NASH, we evaluated reversible phosphorylation events in hepatic tissue derived from Class III obese subjects by phosphoproteomic means with the aim of highlighting key regulatory pathways that distinguish NASH from NAFLD. Class III obese subjects undergoing bariatric surgery underwent liver biopsy (8 NOR, 8 simple steatosis and 8 NASH). Our strategy was unbiased, comparing global differences in liver protein reversible phosphorylation events across the 24 subjects...
March 4, 2017: Hepatology Research: the Official Journal of the Japan Society of Hepatology
https://www.readbyqxmd.com/read/28258315/impact-of-low-level-laser-therapy-on-hyposalivation-salivary-ph-and-quality-of-life-in-head-and-neck-cancer-patients-post-radiotherapy
#5
Luiz Felipe Palma, Fernanda Aurora Stabile Gonnelli, Marcelo Marcucci, Rodrigo Souza Dias, Adelmo José Giordani, Roberto Araújo Segreto, Helena Regina Comodo Segreto
Late effects of radiotherapy for head and neck cancer treatment have been increasingly investigated due to its impact on patients' quality of life. The purpose of this study was to evaluate the effect of low-level laser therapy on hyposalivation, low salivary pH, and quality of life in head and neck cancer patients post-radiotherapy. Twenty-nine patients with radiation-induced xerostomia received laser sessions twice a week, during 3 months (24 sessions). For this, a continuous wave Indium-Gallium-Aluminium-Phosphorus diode laser device was used punctually on the major salivary glands (808 nm, 0...
March 3, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28225525/effects-of-game-performance-on-softball-pitchers-and-catchers
#6
Gretchen D Oliver, Hillary A Plummer, Jessie Washington, Wendi H Weimar, Allison Brambeck
The purpose of this study was to examine the effects of game exposure on pitchers and catchers' hip and glenohumeral range of motion (ROM), isometric strength, and vertical jump performance and power. Five college female softball pitchers (174.24 ± 7.53 cm; 82.10 ± 11.27 kg; 20 ± 1.82 years) and four catchers (165.10 ± 9.04 kg; 68.61 ± 3.87 cm; 20 ± 1.41 years) participated. Hip and glenohumeral rotational ROM; hip and glenohumeral rotational isometric strength; hip abduction and adduction strength; and vertical jump height were assessed pre and post-game exposure...
February 21, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28214960/axonal-disruption-in-white-matter-underlying-cortical-sulcus-tau-pathology-in-chronic-traumatic-encephalopathy
#7
Laurena Holleran, Joong Hee Kim, Mihika Gangolli, Thor Stein, Victor Alvarez, Ann McKee, David L Brody
Chronic traumatic encephalopathy (CTE) is a progressive degenerative disorder associated with repetitive traumatic brain injury. One of the primary defining neuropathological lesions in CTE, based on the first consensus conference, is the accumulation of hyperphosphorylated tau in gray matter sulcal depths. Post-mortem CTE studies have also reported myelin loss, axonal injury and white matter degeneration. Currently, the diagnosis of CTE is restricted to post-mortem neuropathological analysis. We hypothesized that high spatial resolution advanced diffusion MRI might be useful for detecting white matter microstructural changes directly adjacent to gray matter tau pathology...
March 2017: Acta Neuropathologica
https://www.readbyqxmd.com/read/28193321/acute-rehabilitation-after-trauma-does-it-really-matter
#8
Deepika Nehra, Zeynep A Nixon, Claudia Lengenfelder, Eileen M Bulger, Joseph Cuschieri, Ronald V Maier, Saman Arbabi
BACKGROUND: The impact of post-discharge rehabilitation care for the trauma patient remains poorly investigated. Here we describe the functional outcomes of trauma patients discharged to an inpatient rehabilitation facility (IRF), and compare the likelihood of discharge home, 1-year rehospitalization, and 1-year mortality between patients discharged to an IRF and a propensity score-matched cohort of patients not discharged to an IRF. STUDY DESIGN: The Washington State Rehabilitation Registry was used to collect data for all trauma patients discharged to an IRF between 2011 and 2012...
December 2016: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28185011/continuous-intraoperative-epidural-infusions-affect-recovery-room-length-of-stay-and-analgesic-requirements-a-single-center-observational-study
#9
Aalap C Shah, Bala G Nair, Charles F Spiekerman, Laurent A Bollag
PURPOSE: Continuous intraoperative epidural analgesia may improve post-operative pain control and decrease opioid requirements. We investigate the effect of epidural infusion initiation before or after arrival in the post-anesthesia care unit on recovery room duration and post-operative opioid use. METHODS: We performed a retrospective chart review of abdominal, thoracic and orthopedic surgeries where an epidural catheter was placed prior to surgery at the University of Washington Medical Center during a 24 month period...
February 9, 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/28168421/screening-for-distress-using-the-distress-thermometer-and-the-university-of-washington-quality-of-life-in-post-treatment-head-and-neck-cancer-survivors
#10
Naseem Ghazali, Brenda Roe, Derek Lowe, Sank Tandon, Terry Jones, James Brown, Richard Shaw, Janet Risk, Simon N Rogers
The primary aim was to determine the efficacy of the Distress Thermometer (DT) in screening for anxiety and mood problems against the University of Washington Quality of Life, version 4 (UWQOL). Secondary aims were to evaluate the association between demographic, clinical and health-related QOL variables with significant distress. Two hundred and sixty one disease-free HNC ambulatory patients attending routine follow-up clinics were prospectively recruited. Both DT and UWQOL were completed pre-consultation...
February 6, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28160979/plastic-in-cassin-s-auklets-ptychoramphus-aleuticus-from-the-2014-stranding-on-the-northeast-pacific-coast
#11
Hannah P Floren, Gary W Shugart
Oceanic plastic debris found in the digestive tracts of seabirds includes industrial plastic pellets and post-consumer user plastics. We examined whether the amount and type of plastic ingested by Cassin's Auklets (Ptychoramphus aleuticus) is changing by surveying the stomach contents of 171 Cassin's Auklets stranded along the Washington and Oregon coasts in 2014. We found that 41.5% of the birds contained plastic in their ventriculi, similar to values from the North Subarctic Pacific reported in the 1980s...
February 2, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28116917/knowledge-and-social-engagement-change-in-intention-to-be-screened-for-colorectal-cancer
#12
Yamile Molina, Katherine J Briant, Janeth I Sanchez, Mary A O'Connell, Beti Thompson
OBJECTIVE: Innovative technologies have been used to promote colorectal cancer (CRC) screening among the underserved. However, the impact of these innovative technologies on knowledge and social engagement likelihood as they relate to subsequent intention to be screened across different populations has not been fully explored. DESIGN: Using a pre-post-test design with an inflatable walk-through colon, we assessed changes in knowledge and social engagement likelihood across populations and their associations with intention to be screened in two community settings...
January 24, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/28104741/recombinant-human-thyroid-stimulating-hormone-versus-thyroid-hormone-withdrawal-in-124i-pet-ct-based-dosimetry-for-131i-therapy-of-metastatic-differentiated-thyroid-cancer
#13
Donika Plyku, Robert F Hobbs, Kevin Huang, Frank Atkins, Carlos Garcia, George Sgouros, Douglas Van Nostrand
PURPOSE: Patients with metastatic differentiated thyroid cancer (DTC) may be prepared using either thyroid stimulating hormone withdrawal (THW) or recombinant human thyroid-stimulating hormone (rhTSH) injections prior to (131)I administration for treatment. The objective of this study was to compare the absorbed dose (D) to the critical organs and tumors determined by (124)I-Positron Emission Tomography/Computed Tomography (PET/CT) based dosimetry for (131)I therapy of metastatic DTC when the same patient was prepared with and imaged after both THW and rhTSH injections...
January 19, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28077095/geographic-information-system-for-improving-maternal-and-newborn-health-recommendations-for-policy-and-programs
#14
Yordanos B Molla, Barbara Rawlins, Prestige Tatenda Makanga, Marc Cunningham, Juan Eugenio Hernández Ávila, Corrine Warren Ruktanonchai, Kavita Singh, Sylvia Alford, Mira Thompson, Vikas Dwivedi, Allisyn C Moran, Zoe Matthews
This correspondence argues and offers recommendations for how Geographic Information System (GIS) applied to maternal and newborn health data could potentially be used as part of the broader efforts for ending preventable maternal and newborn mortality. These recommendations were generated from a technical consultation on reporting and mapping maternal deaths that was held in Washington, DC from January 12 to 13, 2015 and hosted by the United States Agency for International Development's (USAID) global Maternal and Child Survival Program (MCSP)...
January 11, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28073564/education-and-notification-approaches-for-harmful-algal-blooms-habs-washington-state-usa
#15
F Joan Hardy, Debra Bouchard, Marisa Burghdoff, Ray Hanowell, Beth LeDoux, Ellen Preece, Lindsay Tuttle, Gene Williams
While numerous strategies have been used to educate and notify the public about potential hazards from exposure to Harmful Algal Blooms (HABs), at present there are no national guidelines or suggested outreach approaches. To raise public awareness and determine effective HAB outreach methods, two Washington State agencies and three counties in the Puget Sound region implemented several education and notification strategies. These approaches were rated for effectiveness by state and county public health and water quality professionals...
December 2016: Harmful Algae
https://www.readbyqxmd.com/read/28063773/the-implementation-of-a-naloxone-rescue-program-in-university-students
#16
Shannon G Panther, Brenda S Bray, John R White
OBJECTIVE: Responding to the nationwide opioid overdose epidemic, Washington State University initiated a naloxone safety net project intending to increase awareness of opioid overdose, increase the availability of naloxone, and examine university students' perceptions regarding the usefulness of a novel, large-group audience-training model. SETTING: A Washington State University campus. PRACTICE DESCRIPTION: In September 2014, university students were recruited to attended a large-group audience training event which included opioid overdose prevention, recognition, and first response...
January 4, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/27993924/limited-effectiveness-of-a-skills-and-drills-intervention-to-improve-emergency-obstetric-and-newborn-care-in-karnataka-india-a-proof-of-concept-study
#17
Beena Varghese, Jayanna Krishnamurthy, Blaze Correia, Ruchika Panigrahi, Maryann Washington, Vinotha Ponnuswamy, Prem Mony
OBJECTIVE: The majority of the maternal and perinatal deaths are preventable through improved emergency obstetric and newborn care at facilities. However, the quality of such care in India has significant gaps in terms of provider skills and in their preparedness to handle emergencies. We tested the feasibility, acceptability, and effectiveness of a "skills and drills" intervention, implemented between July 2013 and September 2014, to improve emergency obstetric and newborn care in the state of Karnataka, India...
December 23, 2016: Global Health, Science and Practice
https://www.readbyqxmd.com/read/27955650/development-of-an-ovine-efferent-mammary-lymphatic-cannulation-model-with-minimal-tissue-damage
#18
Hung-Hsun Yen, Elizabeth Washington, Wayne Kimpton, Evan Hallein, Joanne Allen, Silk Yu Lin, Stuart Barber
BACKGROUND: Two mammary lymphatic cannulation models in sheep have been described with minimal use in the past 50 years. The purpose of this study was to investigate a new surgical technique to allow long term monitoring of mammary lymph flow and composition from the mammary glands, with rapid ewe recovery and minimal complications post-surgery. RESULTS: We developed a modified methodology for cannulating the efferent mammary lymphatic from the mammary lymph node with minimum tissue damage...
December 12, 2016: BMC Veterinary Research
https://www.readbyqxmd.com/read/27896667/head-and-neck-rhabdomyosarcoma-clinical-and-pathologic-characterization-of-seven-cases
#19
Eleanor Chen, Robert Ricciotti, Neal Futran, Dolphine Oda
Head and neck rhabdomyosarcoma occurs frequently in children and adolescents, and has been well studied in that population. In contrast, it is rare in adults and is not as well characterized clinically and pathologically. Seven cases of adult rhabdomyosarcoma occurring in head and neck were retrieved from the archives of Department of Pathology and Division of Oral Pathology at University of Washington. Radiologic findings and clinical history, as well as pathologic findings from hematoxylin and eosin slides and immunohistochemistry for myogenic markers were reviewed...
November 28, 2016: Head and Neck Pathology
https://www.readbyqxmd.com/read/27886033/efficacy-of-lytic-staphylococcus-aureus-bacteriophage-against-multidrug-resistant-staphylococcus-aureus-in-mice
#20
Joseph Michael Ochieng' Oduor, Nyamongo Onkoba, Fredrick Maloba, Washingtone Ouma Arodi, Atunga Nyachieo
INTRODUCTION: The use of bacteriophages as an alternative treatment method against multidrug-resistant bacteria has not been explored in Kenya. This study sought to determine the efficacy of environmentally obtained lytic bacteriophage against multidrug-resistant Staphylococcus aureus (MDRSA) bacterium in mice. METHODOLOGY: Staphylococcus aureus bacterium and S. aureus-specific lytic phage were isolated from sewage and wastewater collected within Nairobi County, Kenya...
November 24, 2016: Journal of Infection in Developing Countries
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