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https://www.readbyqxmd.com/read/29422165/evaluating-the-effectiveness-of-pre-operative-platelet-inhibition-testing-to-reduce-costs-and-pre-operative-length-of-stay
#1
Jennifer Bobbitt, Kathleen Petro, Michael Martin
This was a retrospective study to assess the effectiveness of Society of Thoracic Surgeons (STS) Guidelines in reducing resource utilization at Washington Adventist Hospital, Takoma Park, Maryland. Pre and post operative stay (days), platelets and other blood product use, along with hospital costs were compared in elective Cardiac Surgical patients receiving P2Y12 inhibitors in the year prior to and year following the implementation of the STS guidelines of preoperative monitoring of platelet inhibition with VerifyNow...
February 2018: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/29410142/a-randomized-multi-center-study-assessing-the-educational-impact-of-a-computerized-interactive-hysterectomy-trainer-on-gynecology-residents
#2
Allan S Lichtman, William Parker, Barbara Goff, Neeraj Mehra, Eliane M Shore, Guylaine Lefebvre, Alexander Chiang, John Lenihan, Henk W R Schreuder
STUDY OBJECTIVE: To assess improvement of cognitive surgical knowledge of laparoscopic hysterectomy in post-graduate year (PGY) 1 and 2 gynecology residents who used an interactive computer-based Laparoscopic Hysterectomy Trainer. DESIGN: Multicenter prospective, randomized, controlled study (Canadian Taskforce Classification I). SETTING: Five Departments of Obstetrics and Gynecology: Keck School of Medicine of USC; University of California-Los Angeles; University of Washington; University of British Columbia; University of Toronto...
February 1, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29409555/seattle-s-minimum-wage-ordinance-did-not-affect-supermarket-food-prices-by-food-processing-category
#3
Amanda L Spoden, James H Buszkiewicz, Adam Drewnowski, Mark C Long, Jennifer J Otten
OBJECTIVE: To examine the impacts of Seattle's minimum wage ordinance on food prices by food processing category. DESIGN: Supermarket food prices were collected for 106 items using a University of Washington Center for Public Health Nutrition market basket at affected and unaffected supermarket chain stores at three times: March 2015 (1-month pre-policy enactment), May 2015 (1-month post-policy enactment) and May 2016 (1-year post-policy enactment). Food items were categorized into four food processing groups, from minimally to ultra-processed...
February 7, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29408730/potential-effects-of-ionizing-radiation-on-the-evidentiary-value-of-dna-latent-fingerprints-hair-and-fibers-a-comprehensive-review-and-new-results
#4
Keith L Monson, Sherine Ali, Michael D Brandhagen, Martine C Duff, Constance L Fisher, Karen K Lowe, Carna E Meyer, Maria A Roberts, Kyle R Tom, Aaron L Washington
An extensive literature review and new post-irradiation experimental results are presented of genotyping blood stains and hair, and physical examinations of latent fingerprints, hairs, and fibers. Results indicate that successful development of nuclear short tandem repeat (STR) and mitochondrial DNA sequence profiles from human blood and hair evidence is possible-up to a point-following exposure to gamma, neutron, beta, and alpha radiation at several levels that would most likely be present at this type of crime scene (i...
January 31, 2018: Forensic Science International
https://www.readbyqxmd.com/read/29357409/n-acetyl-cysteine-increases-cellular-dysfunction-in-progressive-chronic-kidney-damage-after-acute-kidney-injury-by-dampening-endogenous-antioxidant-responses
#5
David M Small, Washington Y Sanchez, Sandrine F Roy, Christudas Morais, Heddwen L Brooks, Jeff S Coombes, David W Johnson, Glenda C Gobe
Oxidative stress and mitochondrial dysfunction exacerbate acute kidney injury (AKI) but their role in any associated progress to chronic kidney disease (CKD) remains unclear. Antioxidant therapies often benefit AKI but their benefits in CKD are controversial since clinical and pre-clinical investigations often conflict. Here we examined the influence of the antioxidant, N-acetyl cysteine (NAC) on oxidative stress and mitochondrial function during AKI (20-minute bilateral renal ischemia plus reperfusion/IR) and progression to chronic kidney pathologies in mice...
January 10, 2018: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/29355927/early-impact-of-the-affordable-care-act-coverage-expansion-on-safety-net-hospital-inpatient-payer-mix-and-market-shares
#6
Vivian Y Wu, Kathryn R Fingar, H Joanna Jiang, Raynard Washington, Andrew W Mulcahy, Eli Cutler, Gary Pickens
OBJECTIVE: To examine the impact of the Affordable Care Act's coverage expansion on safety-net hospitals (SNHs). STUDY SETTING: Nine Medicaid expansion states. STUDY DESIGN: Differences-in-differences (DID) models compare payer-specific pre-post changes in inpatient stays of adults aged 19-64 years at SNHs and non-SNHs. DATA COLLECTION METHODS: 2013-2014 Healthcare Cost and Utilization Project State Inpatient Databases...
January 21, 2018: Health Services Research
https://www.readbyqxmd.com/read/29352493/effect-of-dietary-manipulation-and-vaccination-of-turkey-breeder-hens-on-immunoglobulin-levels-of-yolk-yolk-sac-and-neonate-poults
#7
A Bhattacharyya, S Majumdar, S K Bhanja, A B Mandal, B B Dash
Two hundred turkey breeder hens and 24 viable toms of 30-35 weeks age of small white variety were distributed into two treatment groups having four replicates of 25 hens and three toms in each treatment. First four replicates were offered a turkey breeder diet (Diet A) (Nutrient requirements of poultry, 1994, National Academic Press, Washington, DC) and the rest four replicates were maintained on a higher plane of nutrition (Diet B) for 8-week duration. After 6 weeks of experimental feeding, two replicates from each treatment groups were vaccinated with ND (R2 B) vaccine...
January 19, 2018: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29332408/effect-of-induction-chemotherapy-on-the-quality-of-life-in-patients-with-advanced-stage-tongue-cancer-by-a-prospective-study
#8
Tao Huang, Hui Liu, Pei Zhang, Yanxia Zhao
Abstracts Objective To assess how induction chemotherapy affects the quality-of-life (QoL) in patients with advanced tongue cancer. Methods This prospective study included patients who were diagnosed with advanced tongue cancer. Each patient was asked to complete the University of Washington QoL (UW-QoL), version 4, questionnaire preoperatively and at 12 months after surgery. Patients were divided into two groups based on whether or not they received induction chemotherapy. Results Of the 192 patients included in the analysis, 145 patients had received induction chemotherapy...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29302291/a-case-series-of-intraosseous-hemangioma-of-the-jaws-various-presentations-of-a-rare-entity
#9
Srinivasa R Chandra, Eleanor Chen, Timothee Cousin, Dolphine Oda
Background: Hemangiomas of the soft tissue are common in the head and neck area, especially in the tongue and in children under ten years of age. Intraosseous hemangiomas of the mandible and maxilla (IHM), on the other hand, are exceedingly rare and are not well characterized. This study presents six IHM cases focusing on the clinical, radiographic, and histologic characteristics. Material and Methods: Six cases of IHM were retrieved from the archives of the Biopsy Services at the University of Washington...
November 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29301440/advancing-the-understanding-of-progression-in-multiple-sclerosis-an-interview-with-shibeshih-belachew
#10
Shibeshih Belachew
Shibeshih Belachew speaks to Laura Dormer, Commissioning Editor: Dr Shibeshih Belachew, MD, PhD, is a Senior Medical Director for Multiple Sclerosis (MS) Disease Area in Global Product Development Medical Affairs at Roche (Basel, Switzerland). Prior to joining Roche in January 2016, he was Director of MS Franchise and Head of Medical Director's office for Biogen Region Europe and Canada. Previously at Biogen he also served as a Director in Global Neurology for the natalizumab program in Cambridge (MA, USA)...
January 5, 2018: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/29299892/cytomegalovirus-infection-after-renal-transplantation-occurrence-clinical-features-and-the-cutoff-for-antigenemia-in-a-university-hospital-in-brazil
#11
Sócrates Bezerra de Matos, Roberto Meyer, Fernanda Washington de Mendonça Lima
BACKGROUND: Cytomegalovirus (CMV) is the main infectious agent causative of morbidity and mortality in transplant recipients. This study aimed to describe the occurrence and clinical features of CMV infection, and the optimum antigenemia assay cutoff associated with symptomatic infection. MATERIALS AND METHODS: This was a cohort study that investigated 87 patients undergoing renal transplantation. The patients were monitored with the CMV antigenemia assay performed weekly for the first 3 months post-transplantation and subsequently, when CMV infection was suspected clinically...
December 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29289941/azithromycin-to-prevent-post-discharge-morbidity-and-mortality-in-kenyan-children-a-protocol-for-a-randomised-double-blind-placebo-controlled-trial-the-toto-bora-trial
#12
Patricia B Pavlinac, Benson O Singa, Grace C John-Stewart, Barbra A Richardson, Rebecca L Brander, Christine J McGrath, Kirkby D Tickell, Mary Amondi, Doreen Rwigi, Joseph B Babigumira, Sam Kariuki, Ruth Nduati, Judd L Walson
INTRODUCTION: Child mortality due to infectious diseases remains unacceptably high in much of sub-Saharan Africa. Children who are hospitalised represent an accessible population at particularly high risk of death, both during and following hospitalisation. Hospital discharge may be a critical time point at which targeted use of antibiotics could reduce morbidity and mortality in high-risk children. METHODS AND ANALYSIS: In this randomised, double-blind, placebo-controlled trial (Toto Bora Trial), 1400 children aged 1-59 months discharged from hospitals in Western Kenya, in Kisii and Homa Bay, will be randomised to either a 5-day course of azithromycin or placebo to determine whether a short course of azithromycin reduces rates of rehospitalisation and/or death in the subsequent 6-month period...
December 29, 2017: BMJ Open
https://www.readbyqxmd.com/read/29281342/a-population-based-survey-of-visual-impairment-and-its-correlates-in-mahabubnagar-district-telangana-state-india
#13
Islay Mactaggart, Sarah Polack, Gvs Murthy, Hannah Kuper
PURPOSE: To estimate the prevalence and correlates of visual impairment in Mahabubnagar district, Telangana, India. METHODS: Fifty-one clusters of 80 people (all ages) were sampled with probability proportionate to size. Households within clusters were selected through the compact segment sampling. Visual acuity (VA) was measured with a tumbling "E" chart. An Ophthalmic Assistant or Vision Technician examined people with VA<6/12 in either eye. Other impairments (hearing, physical) were clinically assessed and self-reported functional difficulties measured using the Washington Group Extended Set...
December 27, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/29248970/a-study-of-the-longitudinal-patterns-of-stimulant-and-amyl-nitrite-use-and-sexual-behavior-pre-and-post-hiv-seroconversion-among-msm
#14
James A Swartz, David McCarty-Caplan
The use of stimulant drugs alone or in combination with amyl nitrites (stimulant/nitrites) has been associated with higher rates of risky sexual behavior and predictive of HIV infection among men who have sex with men. However, the temporal pattern of stimulant/nitrite use pre- and post-seroconversion has not been well established. This study assessed changes in stimulant/nitrite use and risky sexual behavior among seroconverting MSM over time. Data were collected in the Baltimore-Washington, DC; Pittsburgh; Chicago; and Los Angeles sites of the Multicenter AIDS Cohort Study (MACS), a longitudinal study of the natural history of HIV infection among MSM...
December 16, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/29248333/effect-of-automated-prescription-drug-monitoring-program-queries-on-emergency-department-opioid-prescribing
#15
Benjamin C Sun, Christina J Charlesworth, Nicoleta Lupulescu-Mann, Jenny I Young, Hyunjee Kim, Daniel M Hartung, Richard A Deyo, K John McConnell
STUDY OBJECTIVE: We assess whether an automated prescription drug monitoring program intervention in emergency department (ED) settings is associated with reductions in opioid prescribing and quantities. METHODS: We performed a retrospective cohort study of ED visits by Medicaid beneficiaries. We assessed the staggered implementation (pre-post) of automated prescription drug monitoring program queries at 86 EDs in Washington State from January 1, 2013, to September 30, 2015...
December 13, 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/29229452/efficacy-of-human-botulism-immune-globulin-for-the-treatment-of-infant-botulism-the-first-12-years-post-licensure
#16
Jessica R Payne, Jessica M Khouri, Nicholas P Jewell, Stephen S Arnon
OBJECTIVES: To report the efficacy of Human Botulism Immune Globulin Intravenous (BIG-IV) in the first 12 years following its licensure in 2003 and to characterize its use nationwide in treating patients with infant botulism. STUDY DESIGN: Medical records and billing information were collected for US patients treated with BIG-IV from 2003 to 2015. Length of hospital stay (LOS) and hospital charge information for treated patients were compared with the BIG-IV Pivotal Clinical Trial Placebo Group to quantify decreases in LOS and hospital charges...
December 8, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29227236/use-of-marijuana-and-other-substances-among-pregnant-and-parenting-women-with-substance-use-disorders-changes-in-washington-state-after-marijuana-legalization
#17
Therese M Grant, J Christopher Graham, Beatriz H Carlini, Cara C Ernst, Natalie Novick Brown
OBJECTIVE: In 2012, possession of marijuana for nonmedical use was legalized in Washington State. This study examined how legalization affected alcohol and drug use in a sample of pregnant and parenting women with substance use disorders. METHOD: Study participants from nine counties in Washington State (N = 1,359) were questioned about their substance use after completing a 3-year case management intervention program. The sample was divided into two cohorts based on whether participants had completed the program before or after legalization...
January 2018: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/29196471/first-person-lai-kuan-dionne-and-eric-peterman
#18
(no author information available yet)
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Lai Kuan Dionne and Eric Peterman are co-first authors on 'FYCO1 regulates accumulation of post-mitotic midbodies by mediating LC3-dependent midbody degradation', published in Journal of Cell Science. Lai Kuan Dionne is a post-doctoral associate in the lab of Moe Mahjoub at Washington University School of Medicine, investigating the molecular mechanisms of post-mitotic midbody accumulation and secretion in health and diseases...
December 1, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/29177894/understanding-the-factors-that-influence-perceptions-of-post-wildfire-landscape-recovery-across-25-wildfires-in-the-northwestern-united-states
#19
C Kooistra, T E Hall, T Paveglio, M Pickering
Disturbances such as wildfire are important features of forested landscapes. The trajectory of changes following wildfires (often referred to as landscape recovery) continues to be an important research topic among ecologists and wildfire scientists. However, the landscape recovery process also has important social dimensions that may or may not correspond to ecological or biophysical perspectives. Perceptions of landscape recovery may affect people's attitudes and behaviors related to forest and wildfire management...
November 25, 2017: Environmental Management
https://www.readbyqxmd.com/read/29172860/washington-state-spirits-privatization-how-satisfied-were-liquor-purchasers-before-and-after-and-by-type-of-retail-store-in-2014
#20
Thomas K Greenfield, Edwina Williams, William C Kerr, Meenakshi S Subbaraman, Yu Ye
BACKGROUND: In 2012 Washington State ended a wholesale/retail monopoly on liquor, permitting sale of spirits in stores with > 10,000 square feet. Implementation resulted in average price increases, but also five times the stores selling liquor. OBJECTIVES: As part of a privatization evaluation, we studied pre-post and between-store-type purchase experiences. METHODS: A 2010 Washington State Liquor Control Board (LCB) survey of liquor purchasers (n = 599), and the 2014 baseline of a repeated telephone survey (1,202 residents; n = 465 purchasers), each included 10 LCB questions on satisfaction with purchase experiences, each attribute with graded response scale A = 4 to D = 1 and F (0 = fail)...
November 27, 2017: Substance Use & Misuse
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