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Pieter Martens, Seppe Lambeets, Chirikwah Lau, Matthias Dupont, Wilfried Mullens
BACKGROUND: Sacubitril/valsartan reduced heart failure (HF)-admissions and cardiovascular mortality in the PARADIGM-HF-trial. However, real-world patients are often frailer and less able to tolerate high doses of sacubitril/valsartan. METHODS: We performed a retrospective analysis of consecutive patients prescribed sacubitril/valsartan in a single tertiary HF-clinic between December 2016 and January 2018. HF-admissions were assessed in a paired fashion, comparing the amount of antecedent HF-episodes with incident HF-episodes after the initiation...
June 17, 2018: Acta Cardiologica
Liang Xu, Yanchun Chen, Yanni Ji, Song Yang
Factors influencing N-terminal pro-brain natriuretic peptide (NT-proBNP) level in heart failure patients with different cardiac functions were identified to explore the correlations with prognosis. Eighty heart failure patients with different cardiac functions treated in Yixing People's Hospital from January 2016 to June 2017 were selected, and divided into two groups (group with cardiac function in class II and below and group with cardiac function in class III and above), according to the cardiac function classification established by New York Heart Association (NYHA)...
June 2018: Experimental and Therapeutic Medicine
Miranda S Moore, Angelica Bocour, Fabienne Laraque, Ann Winters
OBJECTIVES: The care cascade, a method for tracking population-level progression from diagnosis to cure, is an important tool in addressing and monitoring the hepatitis C virus (HCV) epidemic. However, little agreement exists on appropriate care cascade steps or how best to measure them. The New York City (NYC) Department of Health and Mental Hygiene (DOHMH) sought to construct a care cascade by using laboratory surveillance data with clinically relevant categories that can be readily updated over time...
January 1, 2018: Public Health Reports
Christine Dominianni, Kathryn Lane, Sarah Johnson, Kazuhiko Ito, Thomas Matte
BACKGROUND: Previous studies investigated potential health effects of large-scale power outages, including the massive power failure that affected the northeastern United States and Ontario, Canada, in August 2003, and outages associated with major storms. However, information on localized outages is limited. OBJECTIVE: The study sought to examine potential health impacts of citywide and localized outages in New York City (NYC). METHODS: Along with the citywide 2003 outage, localized outages in July 1999 and July 2006 were identified...
June 2018: Environmental Health Perspectives
Curt Tribble Md
To paraphrase the lyrics of a song by Matchbox Twenty ("It's 3AM, I must be lonely"), it's 3 AM, I must be on a Lear jet. We're heading out to get a pair of lungs for a transplant. It's pitch black out tonight, and there's small rain falling. At least it's not ice or snow, which we've heard is falling to the north of us. I am glad that we'll be heading south on this run. These organ procurement runs tend to violate one of the basic safety rules of flying, which is to avoid, whenever possible, being required to fly...
June 8, 2018: Heart Surgery Forum
Ester Herrmann, Andreas Ecke, Eva Herrmann, Nina Eissing, Stephan Fichtlscherer, Andreas M Zeiher, Birgit Assmus
AIM: Patients with advanced systolic chronic heart failure frequently suffer from progressive functional mitral regurgitation. We report our initial experience in patients with an implanted pulmonary artery pressure (PAP) sensor, who developed severe mitral regurgitation, which was treated with the MitraClip system. We non-invasively compared changes in PAP values in patients after MitraClip with PAP changes in patients without MitraClip. METHODS AND RESULTS: Among 28 patients with New York Heart Association III heart failure with implanted PAP sensor for haemodynamic telemonitoring from a single centre, four patients (age 66 ± 6 years, left ventricular ejection fraction 21 ± 3%, and cardiac index 1...
June 12, 2018: ESC Heart Failure
Rishi Prasad, Stephan Kpoti Gunn, Clarence Alan Rotz, Heather Karsten, Greg Roth, Anthony Buda, Anne M K Stoner
Corn has been a pillar of American agriculture for decades and continues to receive much attention from the scientific community for its potential to meet the food, feed and fuel needs of a growing human population in a changing climate. By midcentury, global temperature increase is expected to exceed 2°C where local effects on heat, cold and precipitation extremes will vary. The Northeast United States is a major dairy producer, corn consumer, and is cited as the fastest warming region in the contiguous U...
2018: PloS One
Rebecca Napier, Steven E McNulty, David T Eton, Margaret M Redfield, Omar AbouEzzeddine, Shannon M Dunlay
OBJECTIVES: This study sought to compare the performance of 2 health-related quality of life (HRQOL) questionnaires in patients with heart failure with preserved ejection fraction (HFpEF). BACKGROUND: The ability to accurately assess HRQOL over time is important in the care of patients with heart failure. The validity and reliability of HRQOL tools including the Minnesota Living with Heart Failure Questionnaire (MLHFQ) and the Kansas City Cardiomyopathy Questionnaire (KCCQ) has not been fully determined or compared in patients with HFpEF...
May 31, 2018: JACC. Heart Failure
Alexandre Bovet, Flaviano Morone, Hernán A Makse
Measuring and forecasting opinion trends from real-time social media is a long-standing goal of big-data analytics. Despite the large amount of work addressing this question, there has been no clear validation of online social media opinion trend with traditional surveys. Here we develop a method to infer the opinion of Twitter users by using a combination of statistical physics of complex networks and machine learning based on hashtags co-occurrence to build an in-domain training set of the order of a million tweets...
June 6, 2018: Scientific Reports
Christine Dominianni, Kathryn Lane, Munerah Ahmed, Sarah Johnson, Wendy McKELVEY, Kazuhiko Ito
Previous studies have shown that higher ambient air temperature is associated with increased incidence of gastrointestinal illnesses, possibly as a result of leaving potentially hazardous food in the temperature danger zone for too long. However, little is known about the effect of hot weather on restaurant practices to maintain safe food temperatures. We examined hot weather impacts on restaurant food safety violations and operations in New York City using quantitative and qualitative methods. We used data from 64,661 inspections conducted among 29,614 restaurants during May to September, 2011 to 2015...
June 6, 2018: Journal of Food Protection
Yajie Tang, Yunhu Song, Fujian Duan, Long Deng, Jun Ran, Ge Gao, Sheng Liu, Yun Liu, Hao Wang, Shihua Zhao, Shengshou Hu
OBJECTIVES: Surgical strategies for patients with midventricular obstruction remain underappreciated. We sought to assess clinical and haemodynamic results, summarize the surgical technique of extended myectomy and provide reliable pre- and intraoperative methods of evaluating patients with midventricular obstruction. METHODS: The preoperative evaluation process, intraoperative surgical strategy and early outcomes were thoroughly reviewed in 40 patients with midventricular obstruction...
June 2, 2018: European Journal of Cardio-thoracic Surgery
Allison Lollier, Elisa M Rodriguez, Frances G Saad-Harfouche, Christy A Widman, Martin C Mahoney
This pilot study was undertaken to identify characteristics and approaches (e.g., social, behavioral, and/or systems factors) which differentiate primary care medical offices achieving higher rates of HPV vaccination. Eligible primary care practice sites providing care to adolescent patients were recruited within an eight county region of western New York State between June 2016 and July 2016. Practice sites were categorized as higher (n = 3) or lower performing (n = 2) based on three dose series completion rates for HPV vaccinations among females aged 13-17 years...
June 2018: Preventive Medicine Reports
Arnaud G L'Huillier, Alireza Eshaghi, C Sarai Racey, Katherene Ogbulafor, Ernesto Lombos, Rachel R Higgins, David C Alexander, Erik Kristjanson, Jocelyn Maregmen, Jonathan B Gubbay, Tony Mazzulli
BACKGROUND: In September 2009, a mumps outbreak originated in New York and spread to Northeastern USA and Canada. This study compares the performance of different diagnostic testing methods used in Ontario and describes molecular characteristics of the outbreak strain. METHODS: Between September 2009 and February 2010, specimens from suspect cases were submitted to Public Health Ontario Laboratory for mumps serology, culture and/or real-time reverse-transcriptase PCR (rRT-PCR) testing...
June 5, 2018: Virology Journal
Cande V Ananth, Marianthi-Anna Kioumourtzoglou, Yongmei Huang, Zev Ross, Alexander M Friedman, Michelle A Williams, Shuang Wang, Murray A Mittleman, Joel Schwartz
BACKGROUND: Despite abruption's elusive etiology, knowledge of triggers that precede it by just a few days prior to delivery may help to understand the underpinnings of this acute obstetrical complication. We examine whether air pollution exposures immediately preceding delivery are associated with acute-onset abruptions. METHODS: We applied a bi-directional, time-stratified, case-crossover design to births with an abruption diagnosis in New York City, 2008-2014...
May 31, 2018: Epidemiology
Lisa A Ruble, John H McGrew, Michael Toland, Nancy Dalrymple, Medina Adams, Claire Snell-Rood
The postsecondary outcomes of individuals with autism spectrum disorder (ASD) are significantly worse than peers with other disabilities. One problem is the lack of empirically-supported transition planning interventions to guide services and help produce better outcomes. We applied an implementation science approach to adapt and modify an evidence-based consultation intervention originally tested with young children called the Collaborative Model for Promoting Competence and Success (COMPASS; Ruble et al., The collaborative model for promoting competence and success for students with ASD...
June 1, 2018: Journal of Autism and Developmental Disorders
Emily S Charlson, Lester Tsai, Marc A Yonkers, Jeremiah P Tao
PURPOSE: To assess the epidemiology of women and underrepresented minorities (URMs; Hispanic, African American, and Native American) in the American Society of Ophthalmic Plastic and Reconstructive Surgery (ASOPRS). METHODS: An observational retrospective study of living ASOPRS members was identified through the ASOPRS member directory, search engine-driven informatics, and direct communication. Members were profiled for gender, race, geographic location, and academic rank (or not)...
May 18, 2018: Ophthalmic Plastic and Reconstructive Surgery
Keith M Diaz, Anusorn Thanataveerat, Faith E Parsons, Sunmoo Yoon, Ying Kuen Cheung, Carmela Alcantara, Andrea T Duran, Ipek Ensari, David J Krupka, Joseph E Schwartz, Matthew M Burg, Karina W Davidson
OBJECTIVES: The purpose of this study, which used mobile technologies to continuously collect data over 1 year, was to examine the association of psychological stress with objectively measured sedentary behavior in adults at both the group (e.g. nomothetic approach) and individual (e.g. idiographic approach) level. METHODS: Data were collected in an observational study of healthy adults (n=79) residing in the New York City metro area who were studied for 365 days from 2014-2015...
May 24, 2018: Psychosomatic Medicine
Peter W Crane, Timothy J Wiegand, Michael Kamali, Marilynn Reif, Rose Wratni, Ronald Montante, Tracey Loveland
INTRODUCTION: Telemedicine and its use in medical toxicology have existed for some time. There are varied definitions, but existing ones center on using currently available forms of audio, video, and internet communications to provide "real-time" patient care. Definitions have historically limited reimbursement but recently expanded CMS guidelines have improved this. Here we describe our experience with telemedicine and reimbursement. METHODS: A retrospective study was conducted of all toxicology and billing reimbursement for fiscal year 2016 for a solo Medical Toxicology service...
May 29, 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
May Hua, Xiaoyue Ma, R Sean Morrison, Guohua Li, Hannah Wunsch
RATIONALE: In the intensive care unit (ICU), studies involving specialized palliative care services have shown decreases in the use of non-beneficial life-sustaining therapies and ICU length of stay for patients. However, whether widespread availability of hospital-based palliative care is associated with less frequent use of high intensity care is unknown. OBJECTIVE: To determine whether availability of hospital-based palliative care is associated with decreased markers of treatment intensity for ICU patients...
May 29, 2018: Annals of the American Thoracic Society
Alexander Liede, Mona Cai, Tamara Fidler Crouter, Daniela Niepel, Fiona Callaghan, D Gareth Evans
PURPOSE: In 2013, Angelina Jolie disclosed in the New York Times (NYT) that she had undergone risk-reducing bilateral mastectomy (RRBM) after learning that she was a BRCA1 mutation carrier. We examined the rates of BRCA testing and RRBM from 1997 to 2016, and quantified trends before and after the Jolie op-ed. METHODS: This observational study of insurance claims data representative of the commercially-insured US population (Truven MarketScan® database) measured BRCA testing and RRBM rates among females ≥ 18 years...
May 28, 2018: Breast Cancer Research and Treatment
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