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Vertebral fracture

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https://www.readbyqxmd.com/read/29155244/letter-to-the-editor-determinants-of-short-term-fracture-risk-in-patients-with-a-recent-history-of-low-trauma-non-vertebral-fracture
#1
Hui-Jie Fan, Shu-Yin Liu, Zhi-Feng Sheng
No abstract text is available yet for this article.
November 16, 2017: Bone
https://www.readbyqxmd.com/read/29154997/kyphoplasty-for-osteoporotic-vertebral-fractures-with-posterior-wall-injury
#2
Ahmed Shawky, Ali Ezzati, Ramachandran Govindasamy, Branko Krajnovic, Belal El-Nady, Galal Zaki Said
BACKGROUND: Cement augmentation techniques are standard treatments for osteoporotic vertebral fractures. Compared to vertebroplasty, kyphoplasty is associated with lower rates of cement leak and better deformity correction, however, posterior wall fractures are relative, but not absolute, contraindications for both techniques and hence treatment practices vary among spine centers. PURPOSE: The primary aim of this study was to assess our center's incidence of posterior cement leakage in osteoporotic vertebral fractures with posterior wall injury treated by balloon kyphoplasty...
November 14, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29154300/fracture-generation-in-human-vertebrae-under-compression-loading-the-influence-of-pedicle-preservation-and-bone-mineral-density-on-in-vitro-fracture-behavior
#3
Michael Kraxenberger, Christian Schröder, Tobias Geith, Andreas Büttner, Christoph von SchulzePeelengahr, Christof Birkenmaier, Peter Muller, Volkmar Jansson, Bernd Wegener
BACKGROUND: Fractured vertebral bodies are a common and wide spread health issue. OBJECTIVE: The purpose of this study was to develop a standardized method to experimentally generate compression fractures in vertebral bodies. The influence of the pedicles has been investigated with regards to the fracture behavior. The correlation between bone mineral density (BMD), the cause of fractures and the fracture behavior was investigated. METHODS: Twenty-one fresh frozen human lumbar spines were examined for bone mineral density (BMD) by means of quantitative computed tomography (qCT)...
November 10, 2017: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/29154265/analysis-of-correlation-between-degeneration-of-lower-lumbar-paraspinal-muscles-and-spinopelvic-alignment-in-patients-with-osteoporotic-vertebral-compression-fracture
#4
Qiguang Li, Jianmin Sun, Xingang Cui, Zhensong Jiang, Tao Li
BACKGROUND: A few studies have pointed that trunk extensors may affect the spinopelvic alignment; however, little is known about the exact association between degeneration of lower lumbar paraspinal muscles and spinopelvic parameters. OBJECTIVE: The study aimed to analyze the relationship between degeneration of lower lumbar paraspinal muscles and spinopelvic alignment in patients with osteoporotic vertebral compression fracture (OVCF). METHODS: Thirty-nine OVCF patients were involved in this study...
November 6, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/29151568/a-comparison-of-the-mini-open-wiltse-approach-with-pedicle-screw-fixation-and-the-percutaneous-pedicle-screw-fixation-for-neurologically-intact-thoracolumbar-fractures
#5
Yong Fan, JiaNan Zhang, Xin He, YunFei Huang, QiNing Wu, DingJun Hao
BACKGROUND The thoracolumbar AO type A3 fracture is an incomplete burst fracture, which affects one vertebral body endplate. The objective of this study was to determine which of two minimal invasive techniques was more suitable for A3 fractures based on clinical and radiographic results. MATERIAL AND METHODS We studied 112 patients with A3 subtype fractures without neurological deficits. A total of 63 patients received percutaneous pedicle screw fixation (PPSF), and 49 patients were treated using mini-open Wiltse approach with pedicle screw fixation (MWPSF)...
November 20, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29150315/surgical-options-for-osteoporotic-vertebral-compression-fractures-complicated-with-spinal-deformity-and-neurologic-deficit
#6
Kalliopi Alpantaki, Michael Dohm, Panagiotis Korovessis, Alexander G Hadjipavlou
INTRODUCTION: This paper describes surgical options for Osteoporotic vertebral compression fracture (OVCF) with acute flexible or chronic rigid kyphosis, and pseudarthrosis complicated with pain and neurologic deficit. METHODS: This study has two components. a) A prospective clinical study of surgical treatment of 31 patients (age: 69±11 years) with either acute flexible or progressive pseudarthrotic kyphosis manifested with severe pain or neurological deficit between 2010 and 2014...
November 12, 2017: Injury
https://www.readbyqxmd.com/read/29149153/analysis-of-reporting-bias-in-vertebral-augmentation
#7
Douglas P Beall, Sean M Tutton, Kieran Murphy, Wayne Olan, Christopher Warner, Jack B Test
Osteoporotic vertebral compression fractures (OVCFs) are a significant cause of morbidity and mortality in the United States and worldwide, with estimates of 750,000 to 1.5 million occurring annually. As the elderly population continues to increase, the incidence of OVCFs will continue to rise, as will the morbidity and mortality associated with this condition. Vertebral augmentation (VA) was almost universally accepted as the appropriate treatment modality prior to 2 sham trials published in 2009 by the New England Journal of Medicine (NEJM)...
November 2017: Pain Physician
https://www.readbyqxmd.com/read/29146094/is-balloon-kyphoplasty-a-better-treatment-than-percutaneous-vertebroplasty-for-chronic-obstructive-pulmonary-disease-copd-patients-with-osteoporotic-vertebral-compression-fractures-ovcfs
#8
Xinjie Wu, Xiangsheng Tang, Mingsheng Tan, Ping Yi, Feng Yang
BACKGROUND: Although several studies reported that Balloon kyphoplasty (BK) or percutaneous vertebroplasty (PVP) could improve pulmonary functions, there is no study to compare the efficacy and safety of 2 procedures in COPD patients with osteoporotic vertebral compression fractures (OVCFs) and investigate the reason why they could improve pulmonary functions. METHOD: Two procedures, including BK and PVP were performed in 61 COPD patients with single-level OVCFS...
November 13, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29145651/cracks-in-the-case-against-epidural-steroids-examining-the-evidence-for-vertebral-fracture-risk
#9
Tina L Doshi, Steven P Cohen
No abstract text is available yet for this article.
November 14, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29145296/approach-to-the-patient-with-pregnancy-and-lactation-associated-osteoporosis-a-case-report-and-a-review-of-the-literature
#10
Min Zhang, Ping Chen, Bin Li, Juan Du, Ting Pan, Jingyan Chen
RATIONALE: Pregnancy and lactation-associated osteoporosis (PLO) is very rare, but it can cause severe vertebral compression fractures with disabling back pain. Although it is a rare, PLO must be kept in mind in the differential diagnosis in patients presenting with low back pain during or after pregnancy. PATIENT CONCERNS: A 23-year-old woman who suffered from lumbago and fractures in the vertebral column 1 month after delivery. DIAGNOSIS: Pregnancy and lactation-associated osteoporosis...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29143901/combined-vertebral-augmentation-and-radiofrequency-ablation-in-the-management-of-spinal-metastases-an-update
#11
REVIEW
Ning Mao Kam, Julian Maingard, Hong Kuan Kok, Dinesh Ranatunga, Duncan Brooks, William C Torreggiani, Peter L Munk, Michael J Lee, Ronil V Chandra, Hamed Asadi
Spinal metastases are the most commonly encountered tumour of the spine, occurring in up to 40% of patients with cancer. Each year, approximately 5% of cancer patients will develop spinal metastases. This number is expected to increase as the life expectancy of cancer patients increases. Patients with spinal metastases experience severe and frequently debilitating pain, which often decreases their remaining quality of life. With a median survival of less than 1 year, the goals of treatment in spinal metastases are reducing pain, improving or maintaining level of function and providing mechanical stability...
November 16, 2017: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/29143131/vertebral-fractures-and-their-association-with-health-related-quality-of-life-back-pain-and-physical-function-in-older-women
#12
Lisa Johansson, Daniel Sundh, Martin Nilsson, Dan Mellström, Mattias Lorentzon
Studies investigating prevalent vertebral fracture (VF) diagnosed using densitometry-based VF assessment (VFA) and associations with physical function, assessed by performance-based measures, are lacking. In this population-based study of 1027 older women, we found that prevalent VF, identified by VFA, was associated with inferior physical health, back pain and inferior physical function. PURPOSE: Several studies have investigated the associations between health-related quality of life (HRQL) and back pain with prevalent VF, detected by spine radiographs, but just a few have been population-based and have used vertebral fracture assessment (VFA) for diagnosing VF...
November 15, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/29143126/-spinal-orthoses-in-the-treatment-of-vertebral-fractures-with-osteoporosis-a-systematic-review-article
#13
REVIEW
M Pfeifer, M Gehlen, C Hinz
This literature search concerning the potential role of spinal orthoses for rehabilitation and treatment of atraumatic vertebral fractures between Th4 and L5 with osteoporosis and without any evidence for a secondary cause, provided no evidence for the benefits of traditional rigid thoracolumbar corsets, which only had a poor compliance. In addition, there are indications that these rigid corsets may even worsen the disease condition especially in the long-term. Wearing these corsets can result in further loss of muscle mass and strength followed by loss of bone and bone mass...
November 15, 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/29143066/-thoracolumbar-spinal-fractures-in-the-elderly-classification-and-treatment
#14
K J Schnake, P Bula, U J Spiegl, M Müller, F Hartmann, B W Ullrich, T R Blattert
Thoracolumbar fractures in the elderly are frequently associated with osteoporosis. Osteoporosis can cause fractures or be a significant comorbidity in traumatic fractures. The OF classification is based on conventional X‑ray, computed tomography (CT) scan and magnetic resonance imaging (MRI). It is easy to use and provides a clinically relevant classification of the fractures. Therapeutic decisions are made based on the clinical and radiological situation by using the OF score. The score takes the current clinical situation including patient-specific comorbidities into consideration...
November 15, 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/29142558/transpedical-interbody-bone-grafting-in-the-treatment-of-senile-osteoporotic-vertebral-fracture
#15
Zhiwei Qin, Hong Liu, Guiying Chen, Guifeng Liu, Peng Zhang, Haitao Zhu
Objective: To evaluate the clinical effect of transpedical interbody bone grafting in the treatment of senile osteoporotic vertebral fracture. Methods: Eighty-six elders with osteoporotic vertebral fracture were selected and divided into a control group and a test group using random double-blind method. Patients in the control group were treated by short-segment transpedicular screw system internal fixation, while patients in the test group were treated by short-segment transpedicular screw system internal fixation in combination with transpedical interbody bone grafting...
September 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29141521/incremental-temperature-cement-delivery-technique-may-prevent-cement-leakage-in-metastatic-vertebral-lesions
#16
Hao Liu, Shenghao Wang, Tao Liu, Bin Meng, Fan He, Rong Zhou, Huilin Yang
OBJECTIVES: To analyze the clinical efficacy and cement leakage rate of percutaneous kyphoplasty (PKP) for the treatment of metastatic vertebral lesions between the two groups using different cement infusion techniques. METHODS: One hundred twenty-nine patients (160 metastatic vertebral fractures) who chose "the incremental temperature cement delivery technique" (ITCDT group) and 105 patients (128 metastatic vertebral fractures) who chose "traditional infusion technique" (TI group) were finally enrolled (nine patients were lost to the follow-up)...
September 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/29137106/trabecular-bone-score-as-a-supplementary-tool-for-the-discrimination-of-osteoporotic-fractures-in-postmenopausal-women-with-rheumatoid-arthritis
#17
Yong Jun Choi, Yoon-Sok Chung, Chang-Hee Suh, Ju-Yang Jung, Hyoun-Ah Kim
Rheumatoid arthritis (RA) is a risk factor for bone fragility, and its effect on fracture risk is independent of bone mineral density (BMD). The trabecular bone score (TBS) is a new indirect parameter of bone quality. In this study, BMD and the TBS were compared between female postmenopausal RA patients with and those without vertebral fractures (VFs).This study had a cross-sectional design. Two hundred seventy-nine postmenopausal women with RA aged 50 years or older were included in this study. TBS measurements were performed on the same vertebrae as those for the BMD measurements...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29136257/risk-factors-for-pathological-fracture-and-metastatic-epidural-spinal-cord-compression-in-patients-with-spinal-metastases
#18
Catherine S Hibberd, Gerald M Y Quan
Vertebral pathological fracture and metastatic epidural spinal cord compression (MESCC) due to metastatic cancer inevitably cause pain, neurological deficit, impaired function, and decreased quality of life and are indications for surgery. In such cases, earlier surgical intervention has the potential to prevent permanent neurological deficit and disability and to maintain function and quality of life. Therefore, the aim of this study was to identify and evaluate risk factors for pathological fracture and MESCC in patients with spinal metastases...
November 11, 2017: Orthopedics
https://www.readbyqxmd.com/read/29129436/effects-of-teriparatide-and-risedronate-on-new-fractures-in-post-menopausal-women-with-severe-osteoporosis-vero-a-multicentre-double-blind-double-dummy-randomised-controlled-trial
#19
David L Kendler, Fernando Marin, Cristiano A F Zerbini, Luis A Russo, Susan L Greenspan, Vit Zikan, Alicia Bagur, Jorge Malouf-Sierra, Péter Lakatos, Astrid Fahrleitner-Pammer, Eric Lespessailles, Salvatore Minisola, Jean Jacques Body, Piet Geusens, Rüdiger Möricke, Pedro López-Romero
BACKGROUND: No clinical trials have compared osteoporosis drugs with incident fractures as the primary outcome. We compared the anti-fracture efficacy of teriparatide with risedronate in patients with severe osteoporosis. METHODS: In this double-blind, double-dummy trial, we enrolled post-menopausal women with at least two moderate or one severe vertebral fracture and a bone mineral density T score of less than or equal to -1·50. Participants were randomly assigned to receive 20 μg of teriparatide once daily plus oral weekly placebo or 35 mg of oral risedronate once weekly plus daily injections of placebo for 24 months...
November 9, 2017: Lancet
https://www.readbyqxmd.com/read/29129406/neuropeptide-y-y2-antagonist-treated-ovariectomized-mice-exhibit-greater-bone-mineral-density
#20
K L Seldeen, P G Halley, C H Volmar, M A Rodríguez, M Hernandez, M Pang, S K Carlsson, L J Suva, C Wahlestedt, B R Troen, S P Brothers
Osteoporosis, a disease characterized by progressive bone loss and increased risk of fracture, often results from menopausal loss of estrogen in women. Neuropeptide Y has been shown to negatively regulate bone formation, with amygdala specific deletion of the Y2 receptor resulting in increased bone mass in mice. In this study, ovariectomized (OVX) mice were injected once daily with JNJ-31020028, a brain penetrant Y2 receptor small molecule antagonist to determine the effects on bone formation. Antagonist treated mice had reduced weight and showed increased whole-body bone mineral density compared to vehicle-injected mice...
November 7, 2017: Neuropeptides
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