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Peter Fonagy

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https://www.readbyqxmd.com/read/27914903/cognitive-behavioural-therapy-and-short-term-psychoanalytical-psychotherapy-versus-a-brief-psychosocial-intervention-in-adolescents-with-unipolar-major-depressive-disorder-impact-a-multicentre-pragmatic-observer-blind-randomised-controlled-superiority-trial
#1
Ian M Goodyer, Shirley Reynolds, Barbara Barrett, Sarah Byford, Bernadka Dubicka, Jonathan Hill, Fiona Holland, Raphael Kelvin, Nick Midgley, Chris Roberts, Rob Senior, Mary Target, Barry Widmer, Paul Wilkinson, Peter Fonagy
BACKGROUND: Psychological treatments for adolescents with unipolar major depressive disorder are associated with diagnostic remission within 28 weeks in 65-70% of patients. We aimed to assess the medium-term effects and costs of psychological therapies on maintenance of reduced depression symptoms 12 months after treatment. METHODS: We did this multicentre, pragmatic, observer-blind, randomised controlled superiority trial (IMPACT) at 15 National Health Service child and adolescent mental health service (CAMHS) clinics in three regions in England...
November 30, 2016: Lancet Psychiatry
https://www.readbyqxmd.com/read/27899055/categorical-and-dimensional-approaches-in-the-evaluation-of-the-relationship-between-attachment-and-personality-disorders-an-empirical-study
#2
Marco Chiesa, Antonella Cirasola, Riccardo Williams, Valentina Nassisi, Peter Fonagy
Although several studies have highlighted the relationship between attachment states of mind and personality disorders, their findings have not been consistent, possibly due to the application of the traditional taxonomic classification model of attachment. A more recently developed dimensional classification of attachment representations, including more specific aspects of trauma-related representations, may have advantages. In this study, we compare specific associations and predictive power of the categorical attachment and dimensional models applied to 230 Adult Attachment Interview transcripts obtained from personality disordered and nonpsychiatric subjects...
November 29, 2016: Attachment & Human Development
https://www.readbyqxmd.com/read/27861799/mentalizing-family-violence-part-1-conceptual-framework
#3
Eia Asen, Peter Fonagy
This is the first of two companion papers describing concepts and techniques of a mentalization-based approach to understanding and managing family violence. We review evidence that attachment difficulties, sudden high levels of arousal, and poor affect control contribute to a loss of mentalizing capacity, which, in turn, undermines social learning and can favor the transgenerational transmission of violent interaction patterns. It is suggested that physically violent acts are only possible if mentalizing is temporarily inhibited or decoupled...
November 11, 2016: Family Process
https://www.readbyqxmd.com/read/27855714/the-nourished-randomised-controlled-trial-comparing-mentalisation-based-treatment-for-eating-disorders-mbt-ed-with-specialist-supportive-clinical-management-sscm-ed-for-patients-with-eating-disorders-and-symptoms-of-borderline-personality-disorder
#4
Paul Robinson, Jennifer Hellier, Barbara Barrett, Daiva Barzdaitiene, Anthony Bateman, Alexandra Bogaardt, Ajay Clare, Nadia Somers, Aine O'Callaghan, Kimberley Goldsmith, Nikola Kern, Ulrike Schmidt, Sara Morando, Catherine Ouellet-Courtois, Alice Roberts, Finn Skårderud, Peter Fonagy
BACKGROUND: In this multi-centre randomized controlled trial (RCT) we compared modified mentalisation-based treatment (MBT-ED) to specialist supportive clinical management (SSCM-ED) in patients with eating disorders (EDs) and borderline personality disorder symptoms (BPD). This group of patients presents complex challenges to clinical services, and a treatment which addresses their multiple problems has the potential to improve outcome. MBT has been shown to be effective in improving outcome in patients with BPD, but its use has not been reported in ED...
November 17, 2016: Trials
https://www.readbyqxmd.com/read/27717374/the-nspcc-uk-minding-the-baby%C3%A2-mtb-home-visiting-programme-supporting-young-mothers-aged-14-25-in-the-first-2%C3%A2-years-of-their-baby-s%C3%A2-life-study-protocol-for-a-randomised-controlled-trial
#5
Elena Longhi, Lynne Murray, Rachael Hunter, David Wellsted, Samantha Taylor-Colls, Kathryn MacKenzie, Gwynne Rayns, Richard Cotmore, Peter Fonagy, Richard M Pasco Fearon
BACKGROUND: Young mothers living in low-income urban settings often are exposed to significant and chronic environmental difficulties including poverty, social isolation and poor education and typically also have to cope with personal histories of abuse and depression. Minding the Baby® (MTB) is an interdisciplinary home-visiting programme developed to support first-time young mothers, which integrates primary care and mental health approaches into a single intensive intervention from the last trimester of pregnancy until the child's second birthday...
October 7, 2016: Trials
https://www.readbyqxmd.com/read/27597820/attachment-neurobiology-and-mentalizing-along-the-psychosis-continuum
#6
REVIEW
Martin Debbané, George Salaminios, Patrick Luyten, Deborah Badoud, Marco Armando, Alessandra Solida Tozzi, Peter Fonagy, Benjamin K Brent
In this review article, we outline the evidence linking attachment adversity to psychosis, from the premorbid stages of the disorder to its clinical forms. To better understand the neurobiological mechanisms through which insecure attachment may contribute to psychosis, we identify at least five neurobiological pathways linking attachment to risk for developing psychosis. Besides its well documented influence on the hypothalamic-pituary-adrenal (HPA) axis, insecure attachment may also contribute to neurodevelopmental risk through the dopaminergic and oxytonergic systems, as well as bear influence on neuroinflammation and oxidative stress responses...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27583809/operationalizing-nimh-research-domain-criteria-rdoc-in-naturalistic-clinical-settings
#7
Carla Sharp, J Christopher Fowler, Ramiro Salas, David Nielsen, Jon Allen, John Oldham, Thomas Kosten, Sanjay Mathew, Alok Madan, B Christopher Frueh, Peter Fonagy
Recently, the National Institute of Mental Health (NIMH) introduced the Research Domain Criteria (RDoC) initiative to address two major challenges facing the field of psychiatry: (1) the lack of new effective personalized treatments for psychiatric disorders, and (2) the limitations associated with categorically defined psychiatric disorders. Although the potential of RDoC to revolutionize personalized psychiatric medicine and psychiatric nosology has been acknowledged, it is unclear how to implement RDoC in naturalistic clinical settings as part of routine outcomes research...
2016: Bulletin of the Menninger Clinic
https://www.readbyqxmd.com/read/27577562/a-randomised-controlled-trial-of-mentalization-based-treatment-versus-structured-clinical-management-for-patients-with-comorbid-borderline-personality-disorder-and-antisocial-personality-disorder
#8
Anthony Bateman, Jennifer O'Connell, Nicolas Lorenzini, Tessa Gardner, Peter Fonagy
BACKGROUND: Antisocial personality disorder (ASPD) is an under-researched mental disorder. Systematic reviews and policy documents identify ASPD as a priority area for further treatment research because of the scarcity of available evidence to guide clinicians and policymakers; no intervention has been established as the treatment of choice for this disorder. Mentalization-based treatment (MBT) is a psychotherapeutic treatment which specifically targets the ability to recognise and understand the mental states of oneself and others, an ability shown to be compromised in people with ASPD...
2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27574314/gene-transcription-profiles-associated-with-inter-modular-hubs-and-connection-distance-in-human-functional-magnetic-resonance-imaging-networks
#9
Petra E Vértes, Timothy Rittman, Kirstie J Whitaker, Rafael Romero-Garcia, František Váša, Manfred G Kitzbichler, Konrad Wagstyl, Peter Fonagy, Raymond J Dolan, Peter B Jones, Ian M Goodyer, Edward T Bullmore
Human functional magnetic resonance imaging (fMRI) brain networks have a complex topology comprising integrative components, e.g. long-distance inter-modular edges, that are theoretically associated with higher biological cost. Here, we estimated intra-modular degree, inter-modular degree and connection distance for each of 285 cortical nodes in multi-echo fMRI data from 38 healthy adults. We used the multivariate technique of partial least squares (PLS) to reduce the dimensionality of the relationships between these three nodal network parameters and prior microarray data on regional expression of 20 737 genes...
October 5, 2016: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/27457931/adolescence-is-associated-with-genomically-patterned-consolidation-of-the-hubs-of-the-human-brain-connectome
#10
Kirstie J Whitaker, Petra E Vértes, Rafael Romero-Garcia, František Váša, Michael Moutoussis, Gita Prabhu, Nikolaus Weiskopf, Martina F Callaghan, Konrad Wagstyl, Timothy Rittman, Roger Tait, Cinly Ooi, John Suckling, Becky Inkster, Peter Fonagy, Raymond J Dolan, Peter B Jones, Ian M Goodyer, Edward T Bullmore
How does human brain structure mature during adolescence? We used MRI to measure cortical thickness and intracortical myelination in 297 population volunteers aged 14-24 y old. We found and replicated that association cortical areas were thicker and less myelinated than primary cortical areas at 14 y. However, association cortex had faster rates of shrinkage and myelination over the course of adolescence. Age-related increases in cortical myelination were maximized approximately at the internal layer of projection neurons...
August 9, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27392018/development-and-validation-of-a-self-report-measure-of-mentalizing-the-reflective-functioning-questionnaire
#11
Peter Fonagy, Patrick Luyten, Alesia Moulton-Perkins, Ya-Wen Lee, Fiona Warren, Susan Howard, Rosanna Ghinai, Pasco Fearon, Benedicte Lowyck
Reflective functioning or mentalizing is the capacity to interpret both the self and others in terms of internal mental states such as feelings, wishes, goals, desires, and attitudes. This paper is part of a series of papers outlining the development and psychometric features of a new self-report measure, the Reflective Functioning Questionnaire (RFQ), designed to provide an easy to administer self-report measure of mentalizing. We describe the development and initial validation of the RFQ in three studies...
2016: PloS One
https://www.readbyqxmd.com/read/27389886/commentary-on-kernberg-and-michels
#12
Peter Fonagy, Elizabeth Allison
No abstract text is available yet for this article.
June 2016: Journal of the American Psychoanalytic Association
https://www.readbyqxmd.com/read/27266443/mindfulness-training-increases-cooperative-decision-making-in-economic-exchanges-evidence-from-fmri
#13
Ulrich Kirk, Xiaosi Gu, Carla Sharp, Andreas Hula, Peter Fonagy, P Read Montague
Emotions have been shown to exert influences on decision making during economic exchanges. Here we investigate the underlying neural mechanisms of a training regimen which is hypothesized to promote emotional awareness, specifically mindfulness training (MT). We test the hypothesis that MT increases cooperative economic decision making using fMRI in a randomized longitudinal design involving 8weeks of either MT or active control training (CT). We find that MT results in an increased willingness to cooperate indexed by higher acceptance rates to unfair monetary offers in the Ultimatum Game...
September 2016: NeuroImage
https://www.readbyqxmd.com/read/27125818/clinical-characteristics-associated-with-the-prescribing-of-ssri-medication-in-adolescents-with-major-unipolar-depression
#14
Lesley Cousins, Kirstie J Whitaker, Barry Widmer, Nick Midgley, Sarah Byford, Bernadka Dubicka, Raphael Kelvin, Shirley Reynolds, Christopher Roberts, Fiona Holland, Barbara Barrett, Robert Senior, Paul Wilkinson, Mary Target, Peter Fonagy, Ian M Goodyer
Unipolar major depressions (MD) emerge markedly during adolescence. National Institute for Health and Care Excellence (NICE) UK recommends psychological therapies, with accompanying selective serotonin reuptake inhibitors (SSRIs) prescribed in severe cases only. Here, we seek to determine the extent and rationale of SSRI prescribing in adolescent MD before entering a randomised clinical trial. SSRI prescribing, together with their clinical characteristics was determined in 465 adolescent patients with MD prior to receiving a standardised psychological therapy as part of the Improving mood with psychoanalytic and cognitive therapies (IMPACT) clinical trial...
December 2016: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/27112740/when-is-truth-relevant
#15
Elizabeth Allison, Peter Fonagy
The authors argue that the experience of knowing and having the truth about oneself known in the context of therapy is not an end in itself; rather, it is important because the trust engendered by this experience (epistemic trust or trust in new knowledge) opens one up to learning about one's social world and finding better ways to live in it. The authors consider the consequences of a lack of epistemic trust in terms of psychopathology.
April 2016: Psychoanalytic Quarterly
https://www.readbyqxmd.com/read/27070273/mentalization-and-dissociation-in-the-context-of-trauma-implications-for-child-psychopathology
#16
Karin Ensink, Michaël Bégin, Lina Normandin, Natacha Godbout, Peter Fonagy
Dissociation is a common reaction subsequent to childhood sexual abuse (CSA) and has been identified as a risk factor for child psychopathology. There is also evidence that mentalization contributes to resilience in the context of abuse. However, at this stage little is known regarding the relationship between mentalization and dissociation, and their respective contributions to psychopathology. The aim of this study was to examine pathways from CSA to depressive symptoms, externalizing behaviour difficulties and sexualized behaviour through mentalization and dissociation...
April 12, 2016: Journal of Trauma & Dissociation
https://www.readbyqxmd.com/read/27064853/offenders-with-antisocial-personality-disorder-display-more-impairments-in-mentalizing
#17
John Newbury-Helps, Janet Feigenbaum, Peter Fonagy
This study was designed to test the hypothesis that individuals with antisocial, particularly violent, histories of offending behavior have specific problems in social cognition, notably in relation to accurately envisioning mental states. Eighty-three male offenders on community license, 65% of whom met the threshold for antisocial personality disorder (ASPD), completed a battery of computerized mentalizing tests requiring perspective taking (Perspectives Taking Test), mental state recognition from facial expression (Reading the Mind in the Eyes Test), and identification of mental states in the context of social interaction (Movie for the Assessment of Social Cognition)...
April 11, 2016: Journal of Personality Disorders
https://www.readbyqxmd.com/read/26939716/randomized-controlled-trial-of-parent-infant-psychotherapy-for-parents-with-mental-health-problems-and-young-infants
#18
Peter Fonagy, Michelle Sleed, Tessa Baradon
There is a dearth of good-quality research investigating the outcomes of psychoanalytic parent-infant psychotherapy (PIP). This randomized controlled trial investigated the outcomes of PIP for parents with mental health problems who also were experiencing high levels of social adversity and their young infants (<12 months). Dyads were clinically referred and randomly allocated to PIP or a control condition of standard secondary and specialist primary care treatment (n = 38 in each group). Outcomes were assessed at baseline and at 6-month and 12-month follow-ups...
March 2016: Infant Mental Health Journal
https://www.readbyqxmd.com/read/26822865/maternal-and-child-reflective-functioning-in-the-context-of-child-sexual-abuse-pathways-to-depression-and-externalising-difficulties
#19
Karin Ensink, Michaël Bégin, Lina Normandin, Peter Fonagy
BACKGROUND: Sexual abuse is a well-recognised risk factor for child psychopathology. Little is known regarding whether child and maternal mentalization can be considered a potential resource or protective factor in this context, respectively, mediating or moderating the relationship between sexual abuse and psychopathology. OBJECTIVE: The aims of this study were (1) to explore the relationships between child and maternal mentalizing, measured as reflective functioning (RF), and child depressive symptoms and externalising difficulties; and (2) to examine whether child mentalizing mediates the relationship between child sexual abuse (CSA) and psychopathology...
2016: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/26808519/psychosocial-intervention-is-associated-with-altered-emotion-processing-an-event-related-potential-study-in-at-risk-adolescents
#20
Hannah L Pincham, Donna Bryce, Danae Kokorikou, Peter Fonagy, R M Pasco Fearon
Emotion processing is vital for healthy adolescent development, and impaired emotional responses are associated with a number of psychiatric disorders. However, it is unclear whether observed differences between psychiatric populations and healthy controls reflect modifiable variations in functioning (and thus could be sensitive to changes resulting from intervention) or stable, non-modifiable, individual differences. The current study therefore investigated whether the Late Positive Potential (LPP; a neural index of emotion processing) can be used as a marker of therapeutic change following psycho-social intervention...
2016: PloS One
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