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https://www.readbyqxmd.com/read/27913565/a-24-year-old-male-with-a-painful-and-cold-lower-extremity
#1
Eric A Robinson, Zain I Khalpey, Rajesh Janardhanan
CLINICAL INTRODUCTION: A 24-year-old male presented to the emergency department with intense pain in his right lower extremity. He has a medical history significant for systemic lupus erythematosus and antiphospholipid syndrome. He also had four prior episodes of deep venous thromboses on rivaroxaban. The patient stated that early in the morning, he started to feel intense pain that started from his knee and progressed to his calf, with associated numbness and paraesthesia. On physical examination, the limb felt cold with absent right popliteal and dorsalis pedis pulses...
December 2, 2016: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/27909513/assessment-of-sinoatrial-node-function-in-patients-with-persistent-and-long-standing-persistent-forms-of-atrial-fibrillation-after-maze-iii-procedure-combined-with-mitral-valve-operation
#2
Kulikov Aleksei A, Bokeria Leo A
RESEARCH OBJECTIVE: Assessment of sinoatrial node function after Maze III procedure combined with a mitral valve operation. METHODS: 100 patients were included in the research with persistent and long-standing persistent forms of atrial fibrillation (AF) and need of operative treatment concerning valve disease. The following preoperative preparation methods were executed to all patients: Electrocardiogram in 12 standard assignments;Two-dimensional echocardiographic with assessment of systolic and diastolic functions of the left ventricle, size of the left atrium and grade of valve disease;Transesophageal echocardiography for exclusion of blood clots in the left atrium and left atrial appendage;Coronary angiography for exclusion of coronary heart disease;Computer tomography for examination of cardiac chambers and anatomic characteristics of pulmonary veins...
June 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27903371/-impact-of-reduced-left-ventricular-ejection-fraction-on-all-cause-mortality-of-75-years-old-and-over-patients-with-moderate-to-severe-aortic-stenosis
#3
Z Li, Y Q Ye, M Y Wang, H Y Xu, S Y Teng, J Qian, W Wang, X Wang, Y J Wu
Objective: To evaluate the impact of left ventricular systolic dysfunction on all-cause mortality of 75 years old and over patients with moderate to severe aortic stenosis. Methods: Clinical data of 301 consecutive aged (≥75 years old) patients with a diagnosis of non-rheumatic moderate to severe aortic stenosis by echocardiography between January 1, 2008 and January 1, 2015 in our hospital were retrospectively analyzed. According to the LVEF, patients were divided into normal LVEF subjects and low LVEF subjects, and the low LVEF level was set at below 60%(≤60%(n=171)vs...
October 24, 2016: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/27896912/balloon-valvuloplasty-to-predict-x-ray-projection-angles-that-are-perpendicular-to-cardiovascular-structures-a-tavi-patient-feasibility-study
#4
Kenneth Fetterly, Kevin Greason, Verghese Mathew
OBJECTIVES: The purpose of this work is to describe methods to measure the 3D angular orientation of cardiovascular structures based on a planar image of a valvuloplasty balloon. These methods facilitate X-ray beam alignment with respect to the anatomy of interest. BACKGROUND: X-ray beam projections which are perpendicular to the long axis of cardiovascular structures are required to support interventional procedures, including transcatheter aortic valve implant (TAVI)...
November 29, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27866224/the-beneficial-effects-of-empagliflozin-an-sglt2-inhibitor-on-atherosclerosis-in-apoe-mice-fed-a-western-diet
#5
Ji Hye Han, Tae Jung Oh, Ghayoung Lee, Hyo Jin Maeng, Dong Hwa Lee, Kyoung Min Kim, Sung Hee Choi, Hak Chul Jang, Hye Seung Lee, Kyong Soo Park, Young-Bum Kim, Soo Lim
AIMS/HYPOTHESIS: A recent large clinical study has shown that empagliflozin has a lower rate of cardiovascular and all-cause mortality when compared with placebo in patients with type 2 diabetes. We investigated the effect of empagliflozin (compared with glimepiride) on the progression of atherosclerosis, and its possible mechanisms of action. METHODS: Forty-eight 5-week-old male ApoE (-/-) mice were fed a western diet for 20 weeks and divided into four groups: control (saline, 154 mmol/l NaCl), glimepiride 0...
November 19, 2016: Diabetologia
https://www.readbyqxmd.com/read/27857929/shunt-overdrainage-caused-by-displacement-of-the-pressure-control-cam-after-pressure-adjustment
#6
Su-Ho Kim, Yoon-Soo Lee, Min-Seok Lee, Sang-Jun Suh, Jeong-Ho Lee, Dong-Gee Kang
Although the Codman-Hakim programmable valve is one of most popular shunt systems used in the clinical practice for the treatment of hydrocephalus, malfunctions related with this system have been also reported which lead to underdrainage or overdrainage of the cerebrospinal fluid. While obstruction of the ventricular catheter by tissue materials or hematoma and catheter disconnection are relatively common, the malfunction of the valve itself is rare. Herein, we report on a rare case of shunt overdrainage caused by displacement of the pressure control cam after pressure adjustment...
October 2016: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/27855469/right-sided-heart-failure-and-extracorporeal-life-support-in-patients-undergoing-pericardiectomy-for-constrictive-pericarditis-a-risk-factor-analysis-for-adverse-outcome
#7
Erik Beckmann, Issam Ismail, Serghei Cebotari, Alexander Busse, Andreas Martens, Malakh Shrestha, Christian Kühn, Axel Haverich, Christine Fegbeutel
Background Right ventricular failure is a life-threatening postoperative complication after pericardiectomy. We conducted a retrospective study with a special emphasis on right ventricular failure. Methods Between June 1997 and September 2011, 69 patients underwent surgical pericardiectomy at our center. Mean age was 59 ( ±  15.5) years, and 49 (71%) patients were male. Causes of constrictive pericarditis included idiopathic (52%, n = 36), tuberculosis (9%, n = 6), postcardiotomy (12%, n = 8), radiation (4%, n = 3), renal insufficiency (12%, n = 8), and autoimmune disease (12%, n = 8)...
November 17, 2016: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/27796666/effects-of-remote-ischemic-preconditioning-on-acute-myocardial-injury-in-patients-undergoing-valve-replacement
#8
Z Cao, R Shen, X Zhang, G Cheng, Z Yan
BACKGROUND: This study investigated the effects of remote ischemic preconditioning (RIPC) on acute myocardial injury and clinical outcome in adult patients undergoing valve replacement surgery. METHODS: Sixty-three adult patients scheduled for elective valve replacement undergoing cardiopulmonary bypass (CPB) were randomly assigned to control or remote ischemic preconditioning treatment. RIPC was applied beginning with the first surgical incision by three times of inflating the cuff to 200 mmHg for 5 min, followed by 5 min of deflation...
October 31, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27784495/-extensive-burns-complicated-with-infective-endocarditis-and-septic-pulmonary-embolism-case-report-and-literature-review
#9
T S Li, Y Qi, Y Wang, Y X Wang, F Y Liu, L Dai, G G Xia
Objective: To improve the clinical recognition of infective endocarditis (IE) and septic pulmonary embolism (SPE) in patients with extensive burns. Methods: A case of large area burn complicated with IE and SPE confirmed by blood cultures and echocardiography was described. A literature review was performed with "burn" and "infective endocarditis" as the Chinese key words in Wanfang database; with "burn" and "infective endocarditis" as Mesh terms in PubMed. Results: The patient was a 37-year-old male with large area burn, who presented with fever and hemoptysis...
October 12, 2016: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/27782572/the-supersonic-molecular-beam-injector-as-a-reliable-tool-for-plasma-fueling-and-physics-experiment-on-hl-2a
#10
C Y Chen, D L Yu, B B Feng, L H Yao, X M Song, L G Zang, X Y Gao, Q W Yang, X R Duan
On HL-2A tokamak, supersonic molecular beam injection (SMBI) has been developed as a routine refueling method. The key components of the system are an electromagnetic valve and a conic nozzle. The valve and conic nozzle are assembled to compose the simplified Laval nozzle for generating the pulsed beam. The appurtenance of the system includes the cooling system serving the cooled SMBI generation and the in situ calibration component for quantitative injection. Compared with the conventional gas puffing, the SMBI features prompt response and larger fueling flux...
September 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27770122/discrepancy-in-blood-pressure-between-the-left-and-right-arms-importance-of-clinical-diagnosis-and-role-of-radiological-imaging
#11
P X Kuan, P W Tan, A T Jobli, A R Norsila
INTRODUCTION: Differences in systolic blood pressure reading between arms are common but could signal trouble if the discrepancy is significant. Early detection of aortic dissection could invariably determine patient's survivability. Hence, a high index of suspicion with prompt diagnostic imaging is vital for accurate diagnosis. CASE PRESENTATION: A previously healthy 35-year-old lady was referred from district hospital for hypertensive cardiomyopathy complicated by acute pulmonary oedema...
August 2016: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/27673368/thermally-induced-triple-shape-hydrogels-soft-materials-enabling-complex-movements
#12
Ulrich Nöchel, Marc Behl, Maria Balk, Andreas Lendlein
Shape-memory hydrogels enable directed movements of a specimen in response to temperature, whereby crystallizable switching segments incorporated as side chains resulted in constant degrees of swelling during the shape-memory cycle. Here we report about hydrogels exhibiting a thermally induced triple-shape effect that allows complex movements of soft materials with two almost independent shape changes. Potential applications for those soft triple-shape materials are two-step self-unfolding devices or temperature-sensitive hydrogel actuators, for example, smart valves for flow rate control in aqueous media...
October 10, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27642739/-an-unexpected-cause-of-dyspnea-and-degradation-of-performance
#13
Peter Seizer, Michaela Rockenstiehl, Suzanne Fateh-Moghadam, Susanne Haen, Ferruh Artunc, Martin R Müller, Azadeh Ebrahimi, Reimer Riessen, Meinrad Gawaz, Falko Fend, Michael Haap
HISTORY AND ADMISSION FINDINGS: A 55-year old man suffers from progressive, distinctive dyspnoea and physical weakness since 5 days. Due to ST-segment changes in the ECG and a positive troponin-test, the primary care physician initiates an hospitalization. INVESTIGATIONS: After admission, the laboratory tests confirm the elevated troponin-values, and show additionally elevated pro-brain-natriuric-peptide-values. The coronary angiography presents a highly reduced left ventricular function, an aortic insufficiency III° and a coronary heart disease...
September 2016: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/27610932/impact-of-latest-generation-cardiac-interventional-x-ray-equipment-on-patient-image-quality-and-radiation-dose-for-trans-catheter-aortic-valve-implantations
#14
Amber J Gislason-Lee, Claire Keeble, Christoper J Malkin, Daniel Egleston, Josephine Bexon, Stephen M Kengyelics, Daniel Blackman, Andrew G Davies
OBJECTIVES: This study aimed to determine whether a reduction in radiation dose was found whilst maintaining a clinically acceptable level of image quality for trans-catheter aortic valve implantation (TAVI) patients using a new cardiac interventional X-ray system with state-of-the-art image enhancement and X-ray optimisation, compared to the cardiac X-ray system which was previously used for TAVI (the reference system). METHODS: Patient dose and image data were retrospectively collected from an AlluraClarity (Philips Healthcare) and Axion Artis (Siemens Healthcare), the new and reference X-ray systems respectively...
September 9, 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27609260/intentional-laceration-of-the-anterior-mitral-valve-leaflet-to-prevent-left-ventricular-outflow-tract-obstruction-during-transcatheter-mitral%C3%A2-valve-replacement-pre-clinical-findings
#15
Jaffar M Khan, Toby Rogers, William H Schenke, Jonathan R Mazal, Anthony Z Faranesh, Adam B Greenbaum, Vasilis C Babaliaros, Marcus Y Chen, Robert J Lederman
OBJECTIVES: The authors propose a novel transcatheter transection of the anterior mitral leaflet to prevent iatrogenic left ventricular outflow tract (LVOT) obstruction during transcatheter mitral valve replacement (TMVR). BACKGROUND: LVOT obstruction is a life-threatening complication of TMVR caused by septal displacement of the anterior mitral leaflet. METHODS: In vivo procedures in swine were guided by biplane x-ray fluoroscopy and intracardiac echocardiography...
September 12, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27540181/survival-adjusted-cancer-risks-attributable-to-radiation-exposure-from-cardiac-catheterisations-in-children
#16
Richard W Harbron, Claire-Louise Chapple, John J O'Sullivan, Kate E Best, Amy Berrington de González, Mark S Pearce
OBJECTIVES: To estimate the risk of developing cancer in relation to the typical radiation doses received from a range of X-ray guided cardiac catheterisations in children, taking variable survival into account. METHODS: Radiation doses were estimated for 2749 procedures undertaken at five UK hospitals using Monte Carlo simulations. The lifetime attributable risk (LAR) of cancer incidence was estimated using models developed by the Biological Effects of Ionising Radiation committee, based on both normal life expectancy, and as a function of attained age, from 20 to 80 years, to take reduced life expectancy into account...
August 18, 2016: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/27512569/the-effect-of-x-ray-beam-distortion-on-the-edwards-sapien-xt-%C3%A2-trans-catheter-aortic-valve-replacement-prosthesis
#17
James A Crowhurst, Karl K Poon, Dale Murdoch, Alexander Incani, Owen C Raffel, Annelise Liddicoat, Darren Walters
INTRODUCTION: Profiling the Aortic root perpendicular to the fluoroscopic image plane will achieve a more successful implant position for trans-catheter aortic valve replacement (TAVR). This study aimed to investigate whether the divergent nature of the X-ray beam from the C-arm altered the appearance of the TAVR device. METHODS: Under bench-top testing, a 23, 26 and 29 mm Edwards Sapien XT valve was positioned coaxially at the bottom of a fluoroscopic image utilising 22 and 32 cm fields of view (FOV)...
December 2015: Journal of Medical Radiation Sciences
https://www.readbyqxmd.com/read/27502134/-comparison-of-anterolateral-minithoracotomy-versus-partial-upper-hemisternotomy-in-aortic-valve-replacement
#18
J Q Shen, L Wei, L M Xia, H Lai, Y X Sun, X N Sun, C Liu, Z H Yang, C S Wang
OBJECTIVE: To compare the results of aortic valve replacement through anterolateral minithoracotomy (RT) and partial upper hemisternotomy (PS) approaches. METHODS: This was a retrospective, observational, cohort study of collected data on 297 patients undergoing isolated primary aortic valve replacement between July 2009 and March 2016 at Department of Cardiovascular Surgery, Zhongshan Hospital, Fudan University. There were 174 male and 123 female patients, aging from 15 to 73 years with a mean age of (51±13) years...
August 1, 2016: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/27461102/transcatheter-heart-valve-crimping-and-the-protecting-effects-of-a-polyester-cuff
#19
R Guidoin, R Zegdi, J Lin, J Mao, O Rochette-Drouin, D How, X Guan, P Bruneval, L Wang, L Germain, Z Zhang
INTRODUCTION: Prior to deployment, the percutaneous heart valves must be crimped and loaded into sheaths of diameters that can be as low as 6mm for a 23mm diameter valve. However, as the valve leaflets are fragile, any damage caused during this crimping process may contribute to reducing its long-term durability in vivo. MATERIAL AND METHOD: Bovine pericardium percutaneous valves were manufactured as follows. The leaflets were sutured on a nitinol frame. A polyester cuff fabric served as a buffer between the pericardium and the stent...
July 22, 2016: Morphologie: Bulletin de L'Association des Anatomistes
https://www.readbyqxmd.com/read/27391776/confined-oriented-and-electrically-anisotropic-graphene-wrinkles-on-bacteria
#20
Shikai Deng, Enlai Gao, Yanlei Wang, Soumyo Sen, Sreeprasad Theruvakkattil Sreenivasan, Sanjay Behura, Petr Král, Zhiping Xu, Vikas Berry
Curvature-induced dipole moment and orbital rehybridization in graphene wrinkles modify its electrical properties and induces transport anisotropy. Current wrinkling processes are based on contraction of the entire substrate and do not produce confined or directed wrinkles. Here we show that selective desiccation of a bacterium under impermeable and flexible graphene via a flap-valve operation produces axially aligned graphene wrinkles of wavelength 32.4-34.3 nm, consistent with modified Föppl-von Kármán mechanics (confinement ∼0...
September 27, 2016: ACS Nano
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