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Arantzazu Zabala, Monika Salgueiro, Oihane Sáez-Atxukarro, Javier Ballesteros, Guillermo Ruiz-Irastorza, Rafael Segarra
OBJECTIVES: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease. Its most prevalent manifestation is neuropsychiatric SLE (NP-SLE), which is characterized by increased involvement of the nervous system, with relevant symptoms, such as marked cognitive deficits, which are directly involved in subsequent functional disability. The objective of this study is to identify and compare the profile of cognitive deficits in patients with NP-SLE and patients with non-neuropsychiatric SLE (nonNP-SLE) by means of a systematic review and meta-analysis...
March 19, 2018: Journal of the International Neuropsychological Society: JINS
Selene Cordeiro Vasconcelos, Iracema da Silva Frazão, Everton Botelho Sougey, Sandra Lopes de Souza, Tatiana de Paula Santana da Silva, Murilo Duarte da Costa Lima
INTRODUCTION: The abuse of alcohol and other drugs is a worldwide problem, the treatment of which poses a challenge to healthcare workers. OBJECTIVE: This study presents a proposal for a systematic review to analyse the psychometric properties of assessment tools developed to measure the self-efficacy of drug users with regard to resisting the urge to take drugs in high-risk situations. METHODS AND ANALYSIS: The guiding question was based on PICOS (Population Intervention Comparator Outcome Setting), and the report of the methods of review protocol was written in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P)...
March 14, 2018: BMJ Open
Lorenzo Pelizza, Silvia Azzali, Federica Paterlini, Sara Garlassi, Ilaria Scazza, Luigi Rocco Chiri, Michele Poletti, Simona Pupo, Andrea Raballo
AIM: The 16-item Prodromal Questionnaire (PQ-16) is a versatile screen tool for routine screening of at-risk individuals. We wished to evaluate the psychometric properties of the Italian version of the PQ-16 (iPQ-16) in a sample of 72 help-seeking adolescents (age range 13-17 years) referred to child and adolescent neuropsychiatry services for diagnostic assessment. METHODS: Participants who completed iPQ-16 were subsequently interviewed with the Comprehensive Assessment of At-Risk Mental States (CAARMS) to confirm the psychosis high risk state...
March 14, 2018: Early Intervention in Psychiatry
R C Jiloha, Prerna Kukreti
Delhi hasn't always enjoyed the status of the India's capital, but it has always played a pivotal role in the history of India as a gateway city. The same way, it received mental health services much later than the rest part of country, but it has witnessed an evolution from colonial era to the birth of state of art modern psychiatry services. Journey started with the landmark inaugural meeting in Delhi University of few visionaries paving the birth of Indian psychiatry society. Subsequently, it witnessed emergence of general hospital psychiatry units & saw their transformation to apex institutes of teaching and research like AIIMS and others...
February 2018: Indian Journal of Psychiatry
Ricardo F Allegri, Pablo Bagnatti
The first step from the neuropsychology in Argentina was in 1883 with the thesis of Antonio Piñeiro about the brain localization of the language and vision disorders, only few years after Broca. The aim of this work has been to describe the development of the neuropsychology in Argentina and its relation with the psychology, neurology and psychiatry. The first period was into the neurology with its French school in?uence. In 1907, Jose Ingeniero published in French his book about "amusia", Cristofredo Jakob the "folia neurobiologica" where he described the organization of the human brain, Vicente Dimitri in 1933 his book "aphasia" and Bernardo de Quiros in 1959 his works about dyslexia...
November 2017: Vertex: Revista Argentina de Psiquiatriá
Rotem Monsa, Michael Peer, Shahar Arzy
BACKGROUND: Conversion disorder (CD), or functional neurological disorder, is manifested as a neurological disturbance that is not macroscopically visible in clinical structural neuroimaging, and is instead ascribed to underlying psychological stress. Known for many years in neuropsychiatry, a comprehensive explanation to the way by which psychological stress leads to a neurological deficit of a structural-like origin is still a mystery. METHODS: We applied whole-brain network-based data-driven analyses on resting-state functional MRI, recorded in seven CD patients with unilateral paresis and hypoesthesia as compared to 15 age-matched healthy controls...
March 6, 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
Ekrem Dere, Anja Ronnenberg, Björn Tampe, Sahab Arinrad, Manuela Schmidt, Elisabeth Zeisberg, Hannelore Ehrenreich
Based on the intellicage paradigm, we have developed a novel cognitive, emotional and social phenotyping battery that permits comprehensive standardized behavioral characterization of mice in an experimenter-independent social setting. Evaluation of this battery in a large number of male and female C57BL/6 wildtype mice, tested in >20 independent cohorts, revealed high reproducibility of the behavioral readouts and may serve as future reference tool. We noticed robust sex-specific differences in general activity, cognitive and emotional behavior, but not regarding preference for social pheromones...
February 20, 2018: Neurobiology of Learning and Memory
Xin Tong, Dongmei An, Markus Reuber, Qin Zhang, Dong Zhou
PURPOSE: This study is intended to provide an overview of diagnostic and treatment services for patients with psychogenic nonepileptic seizures (PNES) across China. METHODS: Using a questionnaire devised by the PNES Task Force of Neuropsychiatry Commission of the International League Against Epilepsy (ILAE), we conducted a survey among Chinese health professionals at the Sixth Advanced International Course: Clinical Epileptology. Descriptive analyses were performed...
January 31, 2018: Seizure: the Journal of the British Epilepsy Association
Yuma Nagata, Hiroyuki Tanaka, Daiki Ishimaru, Masayasu Uematsu, Yasuo Naito, Takashi Nishikawa
AIM: Until now, there has been no instrument to measure the quality of life (QoL) of patients with severe dementia in Japan. The purpose of this study was to translate the Quality of Life in Late-stage Dementia Scale and to evaluate the reliability and validity of the Japanese version (QUALID-J). METHODS: We translated the Quality of Life in Late-stage Dementia into Japanese with permission from the original authors. We assessed a total of 70 dementia patients (14 men, 56 women; mean age: 87...
February 6, 2018: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
Jonathan M Silver
No abstract text is available yet for this article.
2018: Journal of Neuropsychiatry and Clinical Neurosciences
Cheryl M Corcoran, Facundo Carrillo, Diego Fernández-Slezak, Gillinder Bedi, Casimir Klim, Daniel C Javitt, Carrie E Bearden, Guillermo A Cecchi
Language and speech are the primary source of data for psychiatrists to diagnose and treat mental disorders. In psychosis, the very structure of language can be disturbed, including semantic coherence (e.g., derailment and tangentiality) and syntactic complexity (e.g., concreteness). Subtle disturbances in language are evident in schizophrenia even prior to first psychosis onset, during prodromal stages. Using computer-based natural language processing analyses, we previously showed that, among English-speaking clinical (e...
February 2018: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
Kartik Bhatia, Luke Henderson, Mark Yim, Eugene Hsu, Rajiv Dhaliwal
The uncinate fasciculus is the largest white matter association tract connecting the prefrontal cortex and the anteromedial temporal lobe. The traditional anatomical description outlines a temporal stem that hooks around the posterior insula, a subinsular body, and 2 prefrontal stems extending to the lateral orbital gyri and the frontopolar cortex. Recent imaging studies of the white matter tracts deep to the subgenual cingulate gyrus (Brodmann area 25: BA25) suggest the presence of white matter fibers extending from BA25 to the amygdala, via a route that would run in close proximity to the uncinate fasciculus, that are of functional importance in mood disorders...
January 12, 2018: Neuropsychobiology
Fatih Artvinli, Şahap Erkoç, Fulya Kardeş
Introduction: The aim of this article is to provide a brief history of Turkish Neuropsychiatric Society by examining its institutional background, the milestones within its history, and the major activities undertaken by the organization during the years. Methods: Firstly, the books, journals, and articles that are related to the history of psychiatry and neurology in Turkey have been reviewed and the information that can explain the history of the society has been brought together...
December 2017: Noro Psikiyatri Arsivi
Mrigank S Shail
Multiple sclerosis (MS) is an autoimmune disorder where the body attacks its own insulating myelin sheaths covering the nerve cells in the brain and spinal cord. MS patients show signs of mental illness via emotional blunting, liability, apathy, depression, irritability, and psychosis. Many psychiatrists have noted that the symptomatology of mood disorder is very similar to early signs of MS. The mechanism behind the relationship of depression with MS is not entirely understood at this point. However, through advancements in medical imaging techniques, there are now some leading explanations...
November 1, 2017: Curēus
Yuval Eisenberg, Lara R Dugas, Arfana Akbar, Bharathi Reddivari, Brian T Layden, Elena Barengolts
OBJECTIVE: Recently, it has been suggested that oxytocin (OT) has a role in metabolism and neuropsychiatry health and disease, and therefore, it may represent a potential therapeutic target. The current study aimed to investigate relationships between OT and glycemic status along with psycho-social and behavioral factors. DESIGN AND METHODS: A total of 92 obese or overweight, African American, male subjects were enrolled in the study. Biometric and biochemical data were collected including oral glucose tolerance testing and urinary OT (measured by ELISA)...
2018: PloS One
Martien J Kas, Brenda Penninx, Bernd Sommer, Alessandro Serretti, Celso Arango, Hugh Marston
The current nosology of neuropsychiatric disorders allows for a pragmatic approach to treatment choice, regulation and clinical research. However, without a biological rationale for these disorders, drug development has stagnated. The recently EU-funded PRISM project aims to develop a quantitative biological approach to the understanding and classification of neuropsychiatric diseases to accelerate the discovery and development of better treatments. By combining clinical data sets from major worldwide disease cohorts and by applying innovative technologies to deeply phenotype stratified patient groups, we will define a set of quantifiable biological parameters for social withdrawal and cognitive deficits common to Schizophrenia (SZ), Major Depression (MD), and Alzheimer's Disease (AD)...
December 12, 2017: Neuroscience and Biobehavioral Reviews
Greg M Pontone, Kelly A Mills, Gwenn S Smith
No abstract text is available yet for this article.
December 2017: International Review of Psychiatry
L L Zhang, Y Wang, Y Cheng, N Zhang
Objective: To compare the differences in cognitive function and behavioral and psychological symptoms between patients with Alzheimer's disease (AD) and behavioral variant frontotemporal dementia (bvFTD). Methods: Thirty-six AD patients and 20 bvFTD patients at mild-to-moderate stage, who were biomarker-confirmed by positron emission tomography (PET), were assessed with a neuropsychological battery and neuropsychiatry inventory (NPI). Cognitive domains, including memory, language, information processing speed and executive function, and behavioral and psychological symptoms were assessed and compared...
December 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
Suhas Ganesh, Lekhansh Shukla, Arun Kandasamy, Vivek Benegal
Carbamazepine (CBZ) is one of the widely prescribed drugs in the field of neuropsychiatry. We report a case of a 27-year-old female patient presenting with severe cholestatic hepatitis presenting after the initiation of CBZ. We establish the probability of drug-induced liver injury using Council for International Organizations of Medical Sciences/Roussel Uclaf Causality Assessment Method causality assessment scale, and the patient had high probability with a score of 9. We briefly review the literature in this field discussing the scope of the problem, etiopathogenesis, clinical manifestation, course, and management...
September 2017: Indian Journal of Psychological Medicine
Clare M Eddy
Impairments in social cognition may reflect dysfunction of disorder specific or disorder general mechanisms. Although cross-disorder comparison may prove insightful, few studies have compared social cognition in different neuropsychiatric disorders. Parallel investigation of schizophrenia and Tourette syndrome (TS) is encouraged by similarities including the presence of problematic social behavior, echophenomena, emotional dysregulation and dopamine dysfunction. Focusing on tests of social cognition administered in both disorders, this review aims to summarize behavioral, neurophysiological and neuroimaging findings, before exploring how these may contribute to clinical symptoms...
March 2, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
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