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https://www.readbyqxmd.com/read/28435670/type-1-metabotropic-glutamate-receptor-signaling-in-cerebellar-purkinje-cells-in-health-and-disease
#1
REVIEW
Masanobu Kano, Takaki Watanabe
The cerebellum is a brain structure involved in coordination, control, and learning of movements, as well as certain aspects of cognitive function. Purkinje cells are the sole output neurons from the cerebellar cortex and therefore play crucial roles in the overall function of the cerebellum. The type-1 metabotropic glutamate receptor (mGluR1) is a key "hub" molecule that is critically involved in the regulation of synaptic wiring, excitability, synaptic response, and synaptic plasticity of Purkinje cells. In this review, we aim to highlight how mGluR1 controls these events in Purkinje cells...
2017: F1000Research
https://www.readbyqxmd.com/read/28429964/global-mental-health-autonomy-and-medical-paternalism-reconstructing-the-french-ethical-tradition-in-psychiatry
#2
Tiago Pires Marques
In the last few decades, the definition of deontological ethics, a well-identified ethical territory in psychiatry, has been the object of increasing concerns. This has been the case in France, where claims of a specific ethical tradition in psychiatry have accompanied the institutionalization of psychiatric ethics and the perceived globalization of an Anglo-American model of mental health care. This study traces the history of the 'French ethical tradition in psychiatry' and its relationship with establishing institutional spaces for ethical decision-making...
April 1, 2017: History of Psychiatry
https://www.readbyqxmd.com/read/28427932/reciprocal-changes-in-noradrenaline-and-gaba-levels-in-discrete-brain-regions-upon-rapid-eye-movement-sleep-deprivation-in-rats
#3
Rachna Mehta, Sudhuman Singh, Mudasir Ahmad Khanday, Birendra Nath Mallick
Rapid eye movement sleep (REMS) plays important role in maintenance of normal brain functions. Neurons containing various neurotransmitters in different brain regions interact to regulate this complex phenomenon in health and diseases. The number of neuronal projections, their firing rates and neurotransmitter levels vary in different brain regions under various conditions leading to normal or altered patho-physio-behavioral states. In this study using high performance liquid chromatography (HPLC) we quantified noradrenaline (NA) and gamma-amino butyric acid (GABA) levels in locus coeruleus (LC), dorsal raphe (DR), pedunculo-pontine tegmentum (PPT), frontal lobe (FL), cortex and hippocampus (Hippo) in control and after 96 h REMS deprivation (REMSD) rats...
April 17, 2017: Neurochemistry International
https://www.readbyqxmd.com/read/28427388/movement-cognition-and-narration-of-the-emotions-treatment-versus-standard-speech-therapy-in-the-treatment-of-children-with-borderline-intellectual-functioning-a-randomized-controlled-trial
#4
V Blasi, G Baglio, F Baglio, M P Canevini, M Zanette
BACKGROUND: Borderline intellectual functioning (BIF) is defined as a "health meta-condition… characterized by various cognitive dysfunctions associated with an intellectual quotient (IQ) between 71 and 85 which determines a deficit in the individual's functioning both in the restriction of activities and in the limitation of social participation". It can be caused by many factors, including a disadvantaged background and prematurity. BIF affects 7-12% of primary school children that show academic difficulties due to poor executive functioning...
April 20, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28426941/behavioral-deficits-and-neural-damage-of-caenorhabditis-elegans-induced-by-three-rare-earth-elements
#5
Tiantian Xu, Manke Zhang, Jiani Hu, Zihan Li, Taipu Wu, Jianing Bao, Siyu Wu, Lili Lei, Defu He
Rare earth elements (REEs) are widely used in industry, agriculture, medicine and daily life in recent years. However, environmental and health risks of REEs are still poorly understood. In this study, neurotoxicity of trichloride neodymium, praseodymium and scandium were evaluated using nematode Caenorhabditis elegans as the assay system. Median lethal concentrations (48 h) were 99.9, 157.2 and 106.4 mg/L for NdCl3, PrCl3 and ScCl3, respectively. Sublethal dose (10-30 mg/L) of these trichloride salts significantly inhibited body length of nematodes...
April 17, 2017: Chemosphere
https://www.readbyqxmd.com/read/28425426/production-of-red-tilapia-oreochromis-spp-in-floating-cages-in-the-mekong-delta-vietnam-mortality-and-health-management
#6
Annette S Boerlage, Tu Thanh Dung, Tran Thi Hoa, Jeffrey Davidson, Henrik Stryhn, K Larry Hammell
The Mekong Delta in Vietnam is one of the most productive aquaculture regions in the world, in which the red tilapia (Oreochromis spp.) industry is a small-scale industry that mainly supplies local markets in the delta region. Little is known about the frequency of mortality events and health management in this sector. We describe red tilapia floating cage production systems in the Mekong Delta, Vietnam, for the purposes of quantifying mortality and associated production factors, and describing practices that may influence pathogen introduction and spread to and from farms...
April 20, 2017: Diseases of Aquatic Organisms
https://www.readbyqxmd.com/read/28425120/unravelling-swedish-informal-caregivers-generalised-resistance-deficits
#7
Mia M T Wennerberg, Monica Eriksson, Solveig M Lundgren, Ella Danielson
In salutogenic theory, individual/contextual, immaterial/material characteristics enabling movements towards health are labelled Specific and Generalised Resistance Resources, SRRs/GRRs, and characteristics counteracting such movements Specific and Generalised Resistance Deficits, SRDs/GRDs. The aim of this paper was to present SRDs and GRDs described by caregivers as stemming from themselves and their care recipient. Guided by salutogenic theory, an explorative design was used to collect data through interviews with 32 Swedish informal caregivers...
April 20, 2017: Scandinavian Journal of Caring Sciences
https://www.readbyqxmd.com/read/28424088/research-exploring-physical-activity-in-care-homes-reach-study-protocol-for-a-randomised-controlled-trial
#8
Anne Forster, Jennifer Airlie, Karen Birch, Robert Cicero, Bonnie Cundill, Alison Ellwood, Mary Godfrey, Liz Graham, John Green, Claire Hulme, Rebecca Lawton, Vicki McLellan, Nicola McMaster, Amanda Farrin
BACKGROUND: As life expectancy increases and the number of older people, particularly those aged 85 years and over, expands there is an increase in demand for long-term care. A large proportion of people in a care home setting spend most of their time sedentary, and this is one of the leading preventable causes of death. Encouraging residents to engage in more physical activity could deliver benefits in terms of physical and psychological health, and quality of life. This study is the final stage of a programme of research to develop and preliminarily test an evidence-based intervention designed to enhance opportunities for movement amongst care home residents, thereby increasing levels of physical activity...
April 19, 2017: Trials
https://www.readbyqxmd.com/read/28423421/efficacy-of-some-wearable-devices-compared-with-spray-on-insect-repellents-for-the-yellow-fever-mosquito-aedes-aegypti-l-diptera-culicidae
#9
Stacy D Rodriguez, Hae-Na Chung, Kristina K Gonzales, Julia Vulcan, Yiyi Li, Jorge A Ahumada, Hector M Romero, Mario De La Torre, Fangjun Shu, Immo A Hansen
The current Zika health crisis in the Americas has created an intense interest in mosquito control methods and products. Mosquito vectors of Zika are of the genus Aedes, mainly the yellow fever mosquito, Aedes aegypti. L. The use of repellents to alter mosquito host seeking behavior is an effective method for the prevention of mosquito-borne diseases. A large number of different spray-on repellents and wearable repellent devices are commercially available. The efficacies of many repellents are unknown. This study focuses on the efficacy of eleven different repellents in reducing the number of Ae...
January 1, 2017: Journal of Insect Science
https://www.readbyqxmd.com/read/28422928/are-nurse-leaders-prepared-to-lead-across-the-continuum-of-care-in-the-new-paradigm
#10
O Ed Reitz, Shelly Malin
The movement toward linking reimbursement with outcomes necessitates providing care across a continuum of settings, leading to the need for a new healthcare paradigm. Issues related to shifting to this new paradigm include disagreement about what this paradigm encompasses, the fragmentation of the healthcare system, and overreliance on the medical model as a framework for driving health policy decisions. We advocate for nurse leaders to guide the development of this new paradigm.
May 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/28420999/functional-high-intensity-circuit-training-improves-body-composition-peak-oxygen-uptake-strength-and-alters-certain-dimensions-of-quality-of-life-in-overweight-women
#11
Billy Sperlich, Birgit Wallmann-Sperlich, Christoph Zinner, Valerie Von Stauffenberg, Helena Losert, Hans-Christer Holmberg
The effects of circuit-like functional high-intensity training (CircuitHIIT) alone or in combination with high-volume low-intensity exercise (Circuitcombined) on selected cardio-respiratory and metabolic parameters, body composition, functional strength and the quality of life of overweight women were compared. In this single-center, two-armed randomized, controlled study, overweight women performed 9-weeks (3 sessions·wk(-1)) of either CircuitHIIT (n = 11), or Circuitcombined (n = 8). Peak oxygen uptake and perception of physical pain were increased to a greater extent (p < 0...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28420221/a-narrative-review-actigraphy-as-an-objective-assessment-of-perioperative-sleep-and-activity-in-pediatric-patients
#12
REVIEW
Nicole Conrad, Joelle Karlik, Amy Lewandowski Holley, Anna C Wilson, Jeffrey Koh
Sleep is an important component of pediatric health and is crucial for cognitive development. Actigraphy is a validated, objective tool to capture sleep and movement data that is increasingly being used in the perioperative context. The aim of this review is to present recent pediatric studies that utilized actigraphy in the perioperative period, highlight gaps in the literature, and provide recommendations for future research. A literature search was completed using OVID and PubMed databases and articles were selected for inclusion based on relevance to the topic...
April 18, 2017: Children
https://www.readbyqxmd.com/read/28419796/-third-working-conditions-and-health-survey-in-navarre-spain-main-findings
#13
Vega García
OBJECTIVE: To describe health problems and working conditions perceived by workers of Navarra, Spain. METHODS: Conduct of the Third Survey of Working Conditions and Health in Navarre. We administered the Seventh Spanish National Survey of Working Conditions questionnaire by personal interviews conducted in the workers' homes between October 2014 and December 2014, and using a three-stage stratified sampling approach, by economic activity, work establishment size and gender...
April 2017: Archivos de Prevención de Riesgos Laborales
https://www.readbyqxmd.com/read/28419590/cracking-the-neural-code-treating-paralysis-and-the-future-of-bioelectronic-medicine
#14
C Bouton
The human nervous system is a vast network carrying not only sensory and movement information, but also information to and from our organs, intimately linking it to our overall health. Scientists and engineers have been working for decades to tap into this network and 'crack the neural code' by decoding neural signals and learning how to 'speak' the language of the nervous system. Progress has been made in developing neural decoding methods to decipher brain activity and bioelectronic technologies to treat rheumatoid arthritis, paralysis, epilepsy and for diagnosing brain-related diseases such as Parkinson's and Alzheimer's disease...
April 16, 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/28418713/defence-factors-of-vaginal-lactobacilli
#15
S Kovachev
Accurate knowledge of the composition and ecology of the vaginal microbial environment in healthy women is necessary for understanding lactobacilli-dominated normal microbiota and the mechanisms by which it reduces disease risk. The vagina and its microbiota form a balanced ecosystem; any movement outside the normal range for this ecosystem of obligate and/or facultative microbes, termed dysbacteriosis, can lead to infection and disease. This review summarizes recent research on the vaginal ecosystem, the Lactobacillus species that dominate it, and the means by which they suppress the growth, development, and/or proliferation of pathogenic microbial species...
April 18, 2017: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/28418071/chronic-exposure-to-graphene-based-nanomaterials-induces-behavioral-deficits-and-neural-damage-in-caenorhabditis-elegans
#16
Ping Li, Tiantian Xu, Siyu Wu, Lili Lei, Defu He
Nanomaterials of graphene and its derivatives have been widely applied in recent years, but whose impacts on the environment and health are still not well understood. In the present study, the potential adverse effects of graphite (G), graphite oxide nanoplatelets (GO) and graphene quantum dots (GQDs) on the motor nervous system were investigated using nematode Caenorhabditis elegans as the assay system. After being characterized using TEM, SEM, XPS and PLE, three nanomaterials were chronically exposed to C...
April 18, 2017: Journal of Applied Toxicology: JAT
https://www.readbyqxmd.com/read/28414562/a-review-of-cochrane-systematic-reviews-of-interventions-relevant-to-orthoptic-practice
#17
Fiona J Rowe, Sue Elliott, Iris Gordon, Anupa Shah
AIM: To present an overview of the range of systematic reviews on intervention trials pertinent to orthoptic practice, produced by the Cochrane Eyes and Vision group (CEV). METHODS: We searched the 2016 Cochrane Library database (31.03.2016) to identify completed reviews and protocols of direct relevance to orthoptic practice. These reviews are currently completed and published, available on www.thecochranelibrary.com (free to UK health employees) or via the CEV website (http://eyes...
April 17, 2017: Strabismus
https://www.readbyqxmd.com/read/28413117/structure-specific-movement-patterns-in-patients-with-chronic-low-back-dysfunction-using-lumbar-combined-movement-examination
#18
Aubrey P Monie, Roger I Price, Christopher R P Lind, Kevin P Singer
OBJECTIVE: A test-retest cohort study was conducted to assess the use of a novel computer-aided, combined movement examination (CME) to measure change in low back movement after pain management intervention in 17 cases of lumbar spondylosis. Additionally we desired to use a CME normal reference range (NRR) to compare and contrast movement patterns identified from 3 specific structural pathologic conditions: intervertebral disc, facet joint, and nerve root compression. METHODS: Computer-aided CME was used before and after intervention, in a cohort study design, to record lumbar range of movement along with pain, disability, and health self-report questionnaires in 17 participants who received image-guided facet, epidural, and/or rhizotomy intervention...
April 13, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28412692/review-research-on-the-physical-training-model-of-human-body-based-on-hq
#19
Liu Junjie
Health quotient (HQ) is the newest health culture and concept in the 21st century, and the analysis of the human body sports model is not enough mature at present, what's more, the purpose of this paper is to study the integration of the two subjects the health quotient and the sport model. This paper draws the conclusion that physical training and education in colleges and universities can improve the health quotient, and it will make students possess a more healthy body and mind. Then through a new rigid body model of sports to simulate the human physical exercise...
November 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28412580/a-non-toxic-dose-of-cobalt-chloride-blocks-hair-cells-of-the-zebrafish-lateral-line
#20
William J Stewart, Jacob L Johansen, James C Liao
Experiments on the flow-sensitive lateral line system of fishes have provided important insights into the function and sensory transduction of vertebrate hair cells. A common experimental approach has been to pharmacologically block lateral line hair cells and measure how behavior changes. Cobalt chloride (CoCl2) blocks the lateral line by inhibiting calcium movement through the membrane channels of hair cells, but high concentrations can be toxic, making it unclear whether changes in behavior are due to a blocked lateral line or poor health...
April 12, 2017: Hearing Research
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