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https://www.readbyqxmd.com/read/28092722/synthetic-and-natural-peroxisome-proliferator-activated-receptor-ppar-agonists-as-candidates-for-the-therapy-of-the-metabolic-syndrome
#1
Chek Kun Tan, Yan Zhuang, Walter Wahli
Introduction Peroxisome proliferator-activated receptors (PPARs) are the molecular targets of hypolipidemic and insulin-sensitizing drugs and implicated in a multitude of processes that fine-tune the functions of all organs in vertebrates. As transcription factors they sense endogenous and exogenous lipid signaling molecules and convert these signals into intricate gene responses that impact health and disease. The PPARs act as modulators of cellular, organ, and systemic processes, such as lipid and carbohydrate metabolism, making them valuable for understanding body homeostasis influenced by nutrition and exercise...
January 16, 2017: Expert Opinion on Therapeutic Targets
https://www.readbyqxmd.com/read/28092144/exergaming-boxing-versus-heavy-bag-boxing-are-these-equipotent-for-individuals-with-spinal-cord-injury
#2
Maziah Mat Rosly, Hadi Mat Rosly, Nazirah Hasnan, Glen M Davis, Ruby Husain
BACKGROUND: Current strategies for increased physical activity and exercise in individuals with spinal cord injury (SCI) face many challenges with regards to maintaining their continuity of participation. Barriers cited often include problems with accessing facilities, mundane, monotonous or boring exercises and expensive equipment that is often not adapted for wheelchair users. AIM: To compare the physiological responses and user preferences between conventional heavy bag boxing against a novel form of video game boxing, known as exergaming boxing...
January 13, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28091446/correlation-between-athlete-training-intensity-and-cardiac-performance
#3
T Xiao, Y Zhang
OBJECTIVE: An effective analysis of correlation between training intensity of athletes and cardiac performance is done to develop scientific and reasonable exercise program and to promote health of athletes. METHODS: During December 2013-December 2015, 3600 students from different sports schools were selected for the test. All the athletes were randomly grouped, that is half-hour running group, one-hour running group and 90 -minute running group, which are named A, B, C groups respectively...
February 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28091358/a-survey-of-exercise-advice-and-recommendations-in-united-kingdom-paediatric-cardiac-clinics
#4
Craig A Williams, Lucy Gowing, Richard Horn, Alan Graham Stuart
BACKGROUND: Physical activity and exercise have important health benefits for children and adolescents with CHD. The objective of this study was to survey the provision of advice and recommendations in United Kingdom paediatric CHD clinics. METHODS: A three-page questionnaire was sent out to paediatric cardiac consultants in the United Kingdom, paediatric consultants with expertise in cardiology, and nursing staff (Paediatricians with Expertise in Cardiology Special Interest Group), as well as all members of the British Congenital Cardiovascular Association...
January 16, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28090447/quantitative-sodium-magnetic-resonance-imaging-of-cartilage-muscle-and-tendon
#5
REVIEW
Neal K Bangerter, Grayson J Tarbox, Meredith D Taylor, Joshua D Kaggie
Sodium magnetic resonance imaging (MRI), or imaging of the 23Na nucleus, has been under exploration for several decades, and holds promise for potentially revealing additional biochemical information about the health of tissues that cannot currently be obtained from conventional hydrogen (or proton) MRI. This additional information could serve as an important complement to conventional MRI for many applications. However, despite these exciting possibilities, sodium MRI is not yet used routinely in clinical practice, and will likely remain strictly in the domain of exploratory research for the coming decade...
December 2016: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28090397/insights-about-fall-prevention-of-older-adults-in-the-state-of-hawai-i
#6
Yuka Yamazaki, Cullen T Hayashida, Valerie Yontz
The senior population in Hawai'i is growing at a dramatic pace. In the older population, falls and fall-related injuries are leading causes of morbidity and mortality. Moreover, the health care costs for falls are very high. The State of Hawai'i has taken measures to prevent falls through the promotion of medication reviews, vision checks, home assessments, and exercise. However, current published examinations of fall preventive measures have been insufficient, and more research is needed to confirm risk factors, effectiveness of preventive measures, and to explore future objectives...
January 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/28090136/the-impact-of-duration-on-effectiveness-of-exercise-the-implication-for-periodization-of-training-and-goal-setting-for-individuals-who-are-overfat-a-meta-analysis
#7
J E Clark
Given the assumption that all methods of exercise, e.g., endurance (ET), resistance (RT), or combination of both (E+R), can induce a beneficial effect size (ES) for changes in body composition and health status of individuals who are overfat. Thus the aim and purpose of this study is to evaluate the current body of knowledge to address the question as to the impact that the duration of exercise has on its relative effectiveness for inducing health and body compositional changes in individuals who are overfat to assist with developing periodized exercise protocols and establishing short and long term goals...
December 2016: Biology of Sport
https://www.readbyqxmd.com/read/28089898/exercise-guidelines-to-promote-cardiometabolic-health-in-spinal-cord-injured-humans-time-to-raise-the-intensity
#8
Tom E Nightingale, Richard S Metcalfe, Niels Bj Vollaard, James L J Bilzon
Spinal cord injury (SCI) is a life changing event that, as a result of paralysis, negatively influences habitual levels of physical activity and hence cardiometabolic health. Performing regular structured exercise therefore appears extremely important in persons with SCI. However, exercise options are mainly limited to the upper-body, which involves a smaller activated muscle mass compared to the mainly leg-based activities commonly performed by non-disabled individuals. Current exercise guidelines for SCI focus predominantly on relative short durations of moderate-intensity aerobic arm cranking exercise, yet contemporary evidence suggests this is not sufficient to induce meaningful improvements in risk factors for the prevention of cardiometabolic disease in this population...
January 12, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28089610/epidemiology-of-physical-activity-and-exercise-training-in-the-united-states
#9
REVIEW
Peter T Katzmarzyk, I-Min Lee, Corby K Martin, Steven N Blair
The purpose of this review was to provide an overview of the descriptive epidemiology of physical activity (PA) and exercise training in the United States. Overall, there is a low prevalence of meeting the current PA guidelines in all age, sex and race/ethnic groups. Among adults the prevalence of meeting the aerobic component of the guidelines is approximately 51%, whereas the prevalence of meeting both the aerobic and muscle-strengthening guidelines is approximately 23%. Approximately 27% of high school students meet the aerobic component of the pediatric guidelines (60minutes of daily moderate-to-vigorous activity), and the proportion of youth meeting the guidelines decreases with advancing age...
January 12, 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28088897/multiplex-pcr-as-a-rapid-and-sensitive-method-for-identification-of-meat-species-in-halal-meat-products
#10
Mahsa Alikord, Javad Keramat, Mahdi Kadivar, Hassan Momtaz, Mohammad Naghi Eshtiaghi, Aziz Homayouni Rad
BACKGROUND: Species identification and authentication in meat products are important subjects for ensuring the health of consumers. The multiplex-PCR amplification and species-specific primer set were used for identification of horse, donkey, pig and other ruminants in raw and processed meat products. METHODS: Oligonucleotid primers were designed for amplification of species-specific mitochondrial DNA sequences of each species and samples were prepared from binary meat mixtures...
January 13, 2017: Recent Patents on Food, Nutrition & Agriculture
https://www.readbyqxmd.com/read/28088704/an-examination-of-the-anxiolytic-effects-of-exercise-for-people-with-anxiety-and-stress-related-disorders-a-meta-analysis
#11
REVIEW
Brendon Stubbs, Davy Vancampfort, Simon Rosenbaum, Joseph Firth, Theodore Cosco, Nicola Veronese, Giovanni A Salum, Felipe B Schuch
The literature regarding exercise for people with established anxiety disorders is equivocal. To address this issue, we conducted a systematic review and meta-analysis investigating the benefits of exercise compared to usual treatment or control conditions in people with an anxiety and/or stress-related disorders. Major electronic databases were searched from inception until December/2015 and a random effect meta-analysis conducted. Altogether, six randomized control trials (RCTs) including 262 adults (exercise n=132, 34...
January 6, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28088616/patient-agency-and-contested-notions-of-disability-in-social-assistance-applications-in-south-africa
#12
Gabrielle Kelly
Problems in fairly allocating welfare and health resources are very often located in the spaces where citizens interact directly with state workers. This study draws on observations of doctor-patient encounters in disability assessments for the South African disability grant (DG) to examine how doctor-patient interactions and patient agency shape social welfare allocation in a context of high poverty and inequality. Data were gathered via interviews with healthcare workers and observations of doctor-patient interactions in twelve clinics and three hospitals in the Western Cape province between October 2013 and August 2014...
January 9, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28088610/the-effects-of-voluntary-wheel-running-on-neuroinflammatory-status-role-of-monocyte-chemoattractant-protein-1
#13
Lindsay J Spielman, Mehrbod Estaki, Sanjoy Ghosh, Deanna L Gibson, Andis Klegeris
The health benefits of exercise and physical activity (PA) have been well researched and it is widely accepted that PA is crucial for maintaining health. One of the mechanisms by which exercise and PA exert their beneficial effects is through peripheral immune system adaptations. To date, very few studies have looked at the regulation of neuroimmune reactions in response to PA. We studied the effect of voluntary wheel running (VWR) on pro- and anti-inflammatory cytokine levels, patterns of glial cell activation and expression of immune receptors in the brains of female C57BL/6 mice...
January 11, 2017: Molecular and Cellular Neurosciences
https://www.readbyqxmd.com/read/28087891/physical-activity-and-exercise-for-chronic-pain-in-adults-an-overview-of-cochrane-reviews
#14
REVIEW
Louise J Geneen, R Andrew Moore, Clare Clarke, Denis Martin, Lesley A Colvin, Blair H Smith
BACKGROUND: Chronic pain is defined as pain lasting beyond normal tissue healing time, generally taken to be 12 weeks. It contributes to disability, anxiety, depression, sleep disturbances, poor quality of life, and healthcare costs. Chronic pain has a weighted mean prevalence in adults of 20%.For many years, the treatment choice for chronic pain included recommendations for rest and inactivity. However, exercise may have specific benefits in reducing the severity of chronic pain, as well as more general benefits associated with improved overall physical and mental health, and physical functioning...
January 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28087569/exercise-as-treatment-for-alcohol-use-disorders-systematic-review-and-meta-analysis
#15
Mats Hallgren, Davy Vancampfort, Esther S Giesen, Andreas Lundin, Brendon Stubbs
OBJECTIVES: To conduct a systematic review and meta-analysis investigating effects of exercise for people with alcohol use disorders (AUDs) across multiple health outcomes. We also investigated the prevalence and predictors of dropout from exercise studies in AUDs. DESIGN: Systematic review and random effects meta-analysis with meta-regression analyses. DATA SOURCES: 3 major electronic databases were searched from inception until April 2016 for exercise intervention studies in adults with AUDs...
January 13, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28080254/wellness-and-multiple-sclerosis-the-national-ms-society-establishes-a-wellness-research-working-group-and-research-priorities
#16
Robert W Motl, Ellen M Mowry, Dawn M Ehde, Nicholas G LaRocca, Kathy E Smith, Kathleen Costello, Lynne Shinto, Alexander V Ng, Amy B Sullivan, Barbara Giesser, Kevin K McCully, Bo Fernhall, Malachy Bishop, Matthew Plow, Patrizia Casaccia, Nancy D Chiaravalloti
BACKGROUND: People with multiple sclerosis (MS) have identified "wellness" and associated behaviors as a high priority based on "social media listening" undertaken by the National MS Society (i.e. the Society). OBJECTIVE: The Society recently convened a group that consisted of researchers with experience in MS and wellness-related research, Society staff members, and an individual with MS for developing recommendations regarding a wellness research agenda. METHOD: The members of the group engaged in focal reviews and discussions involving the state of science within three approaches for promoting wellness in MS, namely diet, exercise, and emotional wellness...
January 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28079916/adolescent-shin-pain
#17
Jeremy Korsh, Douglas Matijakovich, Charles Gatt
Shin pain is a common complaint in adolescent athletes. The term "shin splints" has historically been applied to these patients. Shin splints, more often than not, refers to a stress reaction of the tibia from overuse. Overuse injuries occur when repetitive microtrauma to the bone exceeds the biologic healing potential. Diagnosis is based on typical history and physical examination findings. Plain radiographs and advanced imaging are rarely necessary but can provide valuable prognostic information. Treatment consists of adequate rest and exercise modification...
January 1, 2017: Pediatric Annals
https://www.readbyqxmd.com/read/28079671/outcomes-of-exercise-training-following-the-use-of-a-birthing-ball-during-pregnancy-and-delivery
#18
Danielle Fournier, Gloria Feeney, Marie-Eve Mathieu
INTRODUCTION: Using a birthing ball (BB) is an exercise form that is growing in popularity. Improved delivery outcomes have been recently reported with as little a 6-8 hours of training per week; however, little is known regarding lower and higher training levels. The aim of the current study was to document whether more time spent training with a BB resulted in improved delivery outcomes for the mother and the newborn. METHODS: This quasi-experimental study was conducted with a sample of women who participated in one to 28 supervised exercise classes during pregnancy according to the Ballon Forme program offered in non-clinical settings (http://ballonforme...
January 4, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28079430/multimodal-prehabilitation-improves-functional-capacity-before-and-after-colorectal-surgery-for-cancer-a-five-year-research-experience
#19
Enrico Maria Minnella, Guillaume Bousquet-Dion, Rashami Awasthi, Celena Scheede-Bergdahl, Francesco Carli
BACKGROUND: Multimodal prehabilitation is a preoperative conditioning intervention in form of exercise, nutritional assessment, whey protein supplementation, and anxiety-coping technique. Despite recent evidence suggesting that prehabilitation could improve functional capacity in patients undergoing colorectal surgery for cancer, all studies were characterized by a relatively small sample size. The aim of this study was to confirm what was previously found in three small population trials...
January 12, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28079394/the-positive-emotions-after-acute-coronary-events-behavioral-health-intervention-design-rationale-and-preliminary-feasibility-of-a-factorial-design-study
#20
Jeffery C Huffman, Ariana M Albanese, Kirsti A Campbell, Christopher M Celano, Rachel A Millstein, Carol A Mastromauro, Brian C Healy, Wei-Jean Chung, James L Januzzi, Linda M Collins, Elyse R Park
BACKGROUND: Positive psychological constructs, such as optimism, are associated with greater participation in cardiac health behaviors and improved cardiac outcomes. Positive psychology interventions, which target psychological well-being, may represent a promising approach to improving health behaviors in high-risk cardiac patients. However, no study has assessed whether a positive psychology intervention can promote physical activity following an acute coronary syndrome. OBJECTIVE: In this article we will describe the methods of a novel factorial design study to aid the development of a positive psychology-based intervention for acute coronary syndrome patients and aim to provide preliminary feasibility data on study implementation...
November 1, 2016: Clinical Trials: Journal of the Society for Clinical Trials
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