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chemotherapy and depression

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https://www.readbyqxmd.com/read/28208082/cognitive-impairment-in-the-first-year-after-breast-cancer-diagnosis-a-prospective-cohort-study
#1
Mariana Ramalho, Filipa Fontes, Luís Ruano, Susana Pereira, Nuno Lunet
OBJECTIVES: The objective of this study was to assess the relation between cancer treatments and incident cognitive impairment in breast cancer patients, taking into account the levels of anxiety before treatment. MATERIALS AND METHODS: We conducted a prospective cohort study with 418 newly diagnosed breast cancer patients with no cognitive impairment, defined as values at least 1.5 standard deviations below age- and education-adjusted cut-offs in the Montreal Cognitive Assessment (MoCA), at baseline...
February 13, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28205449/variations-in-comt-and-ntrk2-influence-symptom-burden-in-women-undergoing-breast-cancer-treatment
#2
Erin E Young, Debra Lynch Kelly, Insop Shim, Kyle M Baumbauer, Angela Starkweather, Debra E Lyon
Women with breast cancer frequently report distressing symptoms during and after treatment that can significantly erode quality of life (QOL). Symptom burden among women with breast cancer is of complex etiology and is likely influenced by disease, treatment, and environmental factors as well as individual genetic differences. The purpose of the present study was to examine the relationships between genetic polymorphisms within Neurotrophic tyrosine kinase receptor 1 (NTRK1), Neurotrophic tyrosine kinase receptor 2 (NTRK2), and catechol-O-methyltransferase ( COMT) and patient symptom burden of QOL, pain, fatigue, anxiety, depression, and sleep disturbance before, during, and after treatment for breast cancer in a subset of participants ( N = 51) in a randomized clinical trial of a novel symptom-management modality for women with breast cancer undergoing chemotherapy...
January 1, 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28198953/predictors-of-hope-among-women-with-breast-cancer-during-chemotherapy
#3
Alessandra Cristina Sartore Balsanelli, Sonia Aurora Alves Grossi
OBJECTIVE: Identifying the predictors of hope in patients with breast cancer during chemotherapy treatment. METHOD: A prospective longitudinal study. The sample was composed of 122 women who responded to the instruments of hope, anxiety and depression, coping, fatigue, religiosity and self-esteem in the first and last cycle of chemotherapy. These variables were used in adjusting the logistic regression model that characterized multivariate statistics, allowing identification of predictor variables...
November 2016: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/28196254/effect-of-a-scalp-cooling-device-on-alopecia-in-women-undergoing-chemotherapy-for-breast-cancer-the-scalp-randomized-clinical-trial
#4
Julie Nangia, Tao Wang, Cynthia Osborne, Polly Niravath, Kristen Otte, Steven Papish, Frankie Holmes, Jame Abraham, Mario Lacouture, Jay Courtright, Richard Paxman, Mari Rude, Susan Hilsenbeck, C Kent Osborne, Mothaffar Rimawi
Importance: Chemotherapy may induce alopecia. Although scalp cooling devices have been used to prevent this alopecia, efficacy has not been assessed in a randomized clinical trial. Objectives: To assess whether a scalp cooling device is effective at reducing chemotherapy-induced alopecia and to assess adverse treatment effects. Design, Setting, and Participants: Multicenter randomized clinical trial of women with breast cancer undergoing chemotherapy...
February 14, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28193310/depressive-symptoms-and-inflammation-are-independent-risk-factors-of-fatigue-in-breast-cancer-survivors
#5
C Xiao, A H Miller, J Felger, D Mister, T Liu, M A Torres
BACKGROUND: Psychosocial and inflammatory factors have been associated with fatigue in breast cancer survivors. Nevertheless, the relative contribution and/or interaction of these factors with cancer-related fatigue have not been well documented. METHOD: This cross-sectional study enrolled 111 stage 0-III breast cancer patients treated with breast surgery followed by whole breast radiotherapy. Fatigue was measured by the total score of the Multidimensional Fatigue Inventory-20...
February 14, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28178754/neuroprotective-effect-of-nebivolol-against-cisplatin-associated-depressive-like-behavior-in-rats
#6
Noha F Abdelkader, Muhammed A Saad, Rania M Abdelsalam
One-third of cancer patients undergoing chemotherapy treatment often display symptoms of depression leading to poor adherence and decreased quality of life. Thus, the current study aimed to investigate the possible protective effect of nebivolol against cisplatin associated depressive symptoms in adult male rats. Nebivolol is a highly cardioselective β-adrenergic receptor blocker that possesses endothelium-dependent vasodilator properties and antioxidant capacities. Animals were allocated into four groups...
February 8, 2017: Journal of Neurochemistry
https://www.readbyqxmd.com/read/28178686/correlation-between-hormone-receptor-status-and-depressive-symptoms-in-patients-with-metastatic-breast-cancer
#7
Xiangyu Guo, Junnan Xu, Ying E, Zhifu Yu, Tao Sun
Individual differences in depressive symptoms correlate with morbidity and outcomes in breast cancer patients. We evaluated the effect of hormone receptor (HR) status on depressive symptoms in 176 women with metastatic breast cancer at diagnosis. To assess depression, the women completed Self-Rating Depression Scale (SDS) questionnaires at baseline examination (T1), after 4 chemotherapy cycles (T2) and after 6 months (T3). At baseline examination, 45/176 (25.6%) patients were found to be at high or medium risk for depression (SDS score ≥0...
February 2, 2017: Oncotarget
https://www.readbyqxmd.com/read/28170295/after-chemotherapy-treatment-for-maternal-cancer-during-pregnancy-is-breastfeeding-possible
#8
Stephen Stopenski, Anum Aslam, Xinmin Zhang, Elyce Cardonick
OBJECTIVE: To report breastfeeding complaints of women diagnosed with cancer during pregnancy and correlate success with characteristics of their treatment. MATERIALS AND METHODS: This is a prospective cohort study of women diagnosed with cancer during pregnancy who attempted breastfeeding. We surveyed participants about breast engorgement, milk let down, and consistent breast milk production through mailed questionnaires. Treatment details, including the type and number of chemotherapy cycles given during pregnancy and antepartum or postpartum depression, were collected...
February 7, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28156652/referral-practices-of-medical-oncologists-to-palliative-care-for-patients-with-metastatic-non-small-cell-lung-cancer-nsclc
#9
Leora Horn, Sharon E Phillips
: 108 Background: Early implementation of palliative care has shown to improve quality of life and prolong survival in pts with metastatic NSCLC. We sought to investigate the attitudes and referral practices among medical oncologists treating pts with metastatic NSCLC. METHODS: Participants were identified through the IASLC 2015 membership directory. All participants were contacted via email to complete an 18-question online survey that included demographic variables as well as questions on referral practice and attitudes regarding the role of palliative care in the treatment of metastatic NSCLC pts...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28156603/benefits-of-cover-makeup-for-survivors
#10
Yuji Heike
: 259 Background: Cancer therapy causes various appearance changes, such as chemotherapy-induced alopecia and skin pigmentation. These events decrease cancer survivors' QoL (quality of life), and sometimes deprive them of social life and work opportunities. Even though wigs are commonly accessible to care hair loss, the way has not been established to care visual changes in skin. Our previous interview survey revealed that visual changes in skin depressed cancer survivors and their daily life were also interrupted, e...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28156556/psychological-distress-in-cancer-patient-during-chemotherapy-a-cross-sectional-study
#11
Raja Banipal
: 231 Background: The State of Punjab is experiencing a rising burden of cancer. The objective of this study was to analyze and compare depression, anxiety and stress levels and their impacting factors in heterogenous surviving cancer patients. METHODS: this is a cross sectional study, data collection was performed by Depression, anxiety, stress scale 21-DASS 21. RESULTS: study population include 300 cancer patients and 300 matched controls...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28154337/investigation-of-mental-disorders-in-lung-cancer-outpatients-a-retrospective-analysis
#12
Yuka Nakamura, Erika Kanemoto, Makoto Kajizono, Yoshihisa Kitamura, Toshiaki Sendo
 Cancer patients often develop mental conditions, including anxiety and depressive disorder. And, patients with chemotherapy often exhibit mental changes including anxiety and depressive disorder. Furthermore, it is well known that the frequency of delirium is increased in cancer patients receiving terminal care. Thus, the psychiatric and cognitive functions of cancer survivors are significantly influenced by their quality of life. In this study, we performed a retrospective analysis to identify the risk factors for psychiatric disorders in lung cancer survivors...
2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28153446/anxiety-depression-and-quality-of-life-in-people-with-pancreatic-cancer-and-their-carers
#13
Monika Janda, Rachel E Neale, Kerenaftali Klein, Dianne L O'Connell, Helen Gooden, David Goldstein, Neil D Merrett, David K Wyld, Ingrid J Rowlands, Vanessa L Beesley
BACKGROUND: People with pancreatic cancer have high levels of anxiety and depression and reduced quality of life (QoL), but few studies have assessed these outcomes for patient-carer dyads. We therefore investigated these issues in an Australian population-based study. METHODS: Patients with pancreatic cancer (n = 136) and many of their carers (n = 84) completed the Hospital Anxiety and Depression Scale (HADS) and Functional Assessment of Cancer Therapy QoL questionnaire at a median of three months after diagnosis...
January 20, 2017: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/28150043/a-prospective-study-of-changes-in-anxiety-depression-and-problems-in-living-during-chemotherapy-treatments-effects-of-age-and-gender
#14
Cristiane Decat Bergerot, Hannah-Rose Mitchell, Kimlin Tam Ashing, Youngmee Kim
PURPOSE: Monitoring distress assessment in cancer patients during the treatment phase is a component of good quality care practice. Yet, there is a dearth of prospective studies examining distress. In an attempt to begin filling this gap and inform clinical practice, we conducted a prospective, longitudinal study examining changes in distress (anxiety, depression, and problems in living) by age and gender and the roles of age and gender in predicting distress. METHODS: Newly diagnosed Brazilian cancer patients (N = 548) were assessed at three time points during chemotherapy...
February 2, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28137529/a-comparative-study-of-art-therapy-in-cancer-patients-receiving-chemotherapy-and-improvement-in-quality-of-life-by-watercolor-painting
#15
H Bozcuk, K Ozcan, C Erdogan, H Mutlu, M Demir, S Coskun
BACKGROUND: There is limited data on the role of art therapy used in cancer patients. We wanted to test the effect of painting art therapy provided by a dedicated professional painting artist on quality of life and anxiety and depression levels in patients having chemotherapy. METHODS: Cancer patients having chemotherapy in the day unit of a medical oncology department of a university hospital were offered to take part in a painting art therapy program (PATP). This program consisted of a professional painting artist facilitating and helping patients to perform painting during their chemotherapy sessions while they were in the day unit, as well as supplying them painting material for home practice...
February 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28133074/-a-case-of-goblet-cell-carcinoid-of-the-appendix-invading-directly-into-the-sigmoid-colon
#16
Satoru Matsumoto, Masahiro Takahashi, Shusaku Takahashi, Hideki Yamagami, Hiroyuki Ishizu
A 73-year-old man underwent a screening colonoscopy, and a depressed lesion in the sigmoid colon was detected. Biopsy revealed a Group V lesion, and he was diagnosed with sigmoid colon cancer. During surgery, there was dense adhesion of the appendix to the sigmoid colon, and sigmoidectomy combined with appendectomy was performed. However, pathological examination revealed goblet cell carcinoid of the appendix with direct invasion into the sigmoid colon. To the best of our knowledge, no similar cases have been reported in Japan...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28132089/effects-of-compensatory-cognitive-training-intervention-for-breast-cancer-patients-undergoing-chemotherapy-a-pilot-study
#17
Jin-Hee Park, Yong Sik Jung, Ku Sang Kim, Sun Hyoung Bae
PURPOSE: Numerous breast cancer patients experience cognitive changes during and after chemotherapy. Chemotherapy-related cognitive impairment can significantly affect quality of life. This pilot study attempted to determine the effects of a compensatory cognitive training on the objective and subjective cognitive functioning of breast cancer patients receiving adjuvant chemotherapy. METHODS: Fifty-four patients were assigned to either a compensatory cognitive training or waitlist condition...
January 28, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28129471/testing-a-novel-account-of-the-dissociation-between-self-reported-memory-problems-and-memory-performance-in-chemotherapy-treated-breast-cancer-survivors
#18
Lise Paquet, Shailendra Verma, Barbara Collins, Anne Chinneck, Marc Bedard, Xinni Song
PURPOSE: A puzzling observation pertaining to the impact of breast cancer (BC) on memory is the frequently reported dissociation between BC survivors self-reported memory problems and memory performance. We evaluated the hypothesis that the dissociation is related to the fact that the objective memory measures previously used assessed retrospective memory (RM) and did not tap prospective memory (PM), a domain about which survivors are complaining. METHODS: In a case-healthy-control (N = 80) cross-sectional study, the Memory for Intention Screening Test was used to assess PM and the Wechsler Logical Memory Test was employed to evaluate RM...
January 27, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28107336/symptom-management-the-effects-of-self-affirmation-on-chemotherapy-related-symptoms
#19
Meltem Yildirim, Hatice Gulsoy, Makbule Batmaz, Cansu Ozgat, Gulser Yesilbursali, Reyhan Aydin, Sedanur Ekiz
BACKGROUND: Positive effects of auditory stimulations are common in symptom management. However, the effect of self-affirmations on symptom management is not well known. OBJECTIVES: The purpose of this study is to investigate the effects of self-affirmations and nature sounds on chemotherapy-related symptoms. METHODS: This randomized, controlled experimental study was conducted with 140 patients receiving chemotherapy. The first experimental group listened to affirmations, the second listened to nature sounds, and the third listened to both...
1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28102437/a-comparison-of-the-effects-of-medical-qigong-and-standard-exercise-therapy-on-symptoms-and-quality-of-life-in-patients-with-advanced-cancer
#20
B L Vanderbyl, M J Mayer, C Nash, A T Tran, T Windholz, T Swanson, G Kasymjanova, R T Jagoe
PURPOSE: Patients with advanced cancer frequently experience anxiety, depression and poor quality of life (QOL), as well as physical symptoms such as fatigue and weakness. Physical exercise has potential to help control these symptoms but the optimal training prescription is still not clear. We performed a study comparing medical Qigong (QG) and standard endurance and strength training (SET) in patients with advanced stage non-small cell lung (NSCLC) and gastrointestinal (GI) cancers...
January 19, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
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