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https://www.readbyqxmd.com/read/29155948/predictors-of-fatigue-and-work-ability-in-cancer-survivors
#1
P van Muijen, S F A Duijts, K Bonefaas-Groenewoud, A J van der Beek, J R Anema
Background: Workers diagnosed with cancer are at risk for job loss or work disability. Aims: To determine predictors of fatigue and work ability at 36 months after diagnosis in a population of cancer survivors. Methods: Individuals diagnosed with cancer and who applied for work disability benefit at 24 months of sick leave were surveyed at the time of application and again 12 months later. Fatigue was measured using the Functional Assessment of Chronic Illness-Fatigue scale questionnaire and work ability was measured using the work ability index...
November 16, 2017: Occupational Medicine
https://www.readbyqxmd.com/read/29153555/a-prospective-follow-up-of-quality-of-life-depression-and-anxiety-in-children-with-lymphoma-and-solid-tumors
#2
Nihal Sargın Yıldırım, Metin Demirkaya, Betül Berrin Sevinir, Salih Güler, Ayşe Pınar Vural, Candan Demiröz, Arzu Çırpan Kantarcıoğlu
Background/aim: The aim of this study was the determination and prospective follow-up of quality of life, depression, and anxiety in pediatric patients with cancer under chemotherapy, as well as the evaluation of related factors. Materials and methods: Fifty newly diagnosed pediatric cancer patients and their parents were prospectively monitored before, during, and after therapy, and tests were used. Results: Significantly lower quality of life scores were recorded during treatment, in the group with CNS tumors, in the group receiving chemotherapy plus radiotherapy plus surgery, in the inpatient-only treatment group, in the group receiving treatment for longer than 6 months, and in the group of patients whose diagnosis was delayed for more than 3 months...
August 23, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29145033/is-chronic-postsurgical-pain-surgery-induced-a-study-of-persistent-postoperative-pain-following-breast-reconstruction
#3
Randy S Roth, Ji Qi, Jennifer B Hamill, Hyungjin M Kim, Tiffany N S Ballard, Andrea L Pusic, Edwin G Wilkins
BACKGROUND: Chronic postsurgical pain (CPSP) is a reported risk for women undergoing breast reconstruction, but it remains unclear that such persistent pain is induced by reconstructive surgery. To address this concern, this prospective cohort study examined the prevalence of and risk factors associated with CPSP among women undergoing breast reconstruction. MATERIALS AND METHODS: Women (n = 1996) recruited for the Mastectomy Reconstruction Outcomes Consortium (MROC) Study were assessed preoperatively and at two-years postoperatively for relevant medical/...
November 13, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29126815/analysis-of-suicide-risk-in-patients-with-penile-cancer-and-review-of-the-literature
#4
REVIEW
William G Simpson, Zachary Klaassen, Rita P Jen, William M Hughes, Durwood E Neal, Martha K Terris
The treatment for penile cancer has been shown to cause harmful psychiatric symptoms as well as have detrimental effects on well-being. In the past several years, alternatives to total or partial penectomy have emerged, such as chemotherapy, radiation, penile sparing, and laser ablation therapies. A more specific breakdown for penile cancer is in order as the therapy has the potential for life changing surgery. We examined the Surveillance, Epidemiology, and End Results (SEER) database (1973-2013), comprising 28% of the United States population...
October 3, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/29123662/chronic-postsurgical-pain-is-there-a-possible-genetic-link
#5
Sabu Kumar James
Persistent or chronic postsurgical pain (CPSP) has been defined as 'pain persisting beyond 2 months'. The cut-off limit of 2 months has been controversial, and some researchers argue for a 3-month period for the definition of CPSP. Multiple mechanisms, including both patient and surgical, have been shown to influence this transition. Patient factors include age, gender, anxiety, depression, somatisation, catastrophising, pre-existing pain anywhere and pain at the site of surgery. The various surgical factors include site and nature of surgery, infection, inflammation and repeat surgery...
November 2017: British Journal of Pain
https://www.readbyqxmd.com/read/29123357/complementary-therapies-for-symptom-management-in-cancer-patients
#6
Aanchal Satija, Sushma Bhatnagar
Cancer patients are often poly-symptomatic which distressingly affects their quality of lives (QOLs). Alhough, conventional management provides adequate symptom control, yet is coupled with some limitations. Complementary therapies (CTs) have shown beneficial effects in cancer patients for symptomatic relief. The aim of this article is to provide evidence-based review of commonly used CTs for symptom management in cancer care. Hypnosis has promising evidence to be used for managing symptoms such as pain, chemotherapy-induced nausea/vomiting, distress, fatigue, and hot flashes...
October 2017: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/29123345/effect-of-supportive-psychotherapy-on-mental-health-status-and-quality-of-life-of-female-cancer-patients-receiving-chemotherapy-for-recurrent-disease
#7
Anindita Mukherjee, Koustav Mazumder, Vikrant Kaushal, Sushmita Ghoshal
Context: Cancer patients receiving chemotherapy for their recurrent disease often report the presence of anxiety and depression. Aims: In the study, we intended to find out the mental health status and overall quality of life (QOL) of such patients and to identify the effect of supportive psychotherapy. Subjects and Methods: Forty cancer patients undergoing second or subsequent line chemotherapy(CCT) were selected for psychotherapy session...
October 2017: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/29116555/modifiable-correlates-of-perceived-cognitive-function-in-breast-cancer-survivors-up-to-10%C3%A2-years-after-chemotherapy-completion
#8
Ashley Henneghan, Alexa Stuifbergen, Heather Becker, Shelli Kesler, Elisabeth King
BACKGROUND: Cognitive changes following breast cancer treatment are likely multifactorial and have been linked to emotional factors, biophysiological factors, and fatigue, among others. Little is known about the contributions of modifiable factors such as stress, loneliness, and sleep quality. The purpose of this study was to explore the direct and indirect effects of perceived stress, loneliness, and sleep quality on perceived cognitive function (PCF) in breast cancer survivors (BCS) after chemotherapy completion...
November 7, 2017: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/29115823/an-overview-of-the-clinical-uses-pharmacology-and-safety-of-modafinil
#9
Eric Murillo-Rodriguez, André Barciela Veras, Nuno Barbosa Rocha, Henning Budde, Sérgio Machado
Modafinil (MOD) is a drug used for the management of excessive daytime sleepiness observed in several sleep disturbances such as shift work sleep disorder, obstructive sleep apnea, restless leg syndrome and narcolepsy. Additionally, a wide scope of medical uses of MOD have been described such as fatigue in subjects with depression as well as patients under chemotherapy. Moreover, there also appear to be a cognitive enhancer drug. In contrast, recent reports have indicated the risk of developing addiction to MOD...
November 8, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/29110150/the-effect-of-an-aerobic-exercise-bout-24%C3%A2-h-prior-to-each-doxorubicin-treatment-for-breast-cancer-on-markers-of-cardiotoxicity-and-treatment-symptoms-a-rct
#10
Amy A Kirkham, Neil D Eves, Rob E Shave, Kelcey A Bland, Joshua Bovard, Karen A Gelmon, Sean A Virani, Don C McKenzie, Eric J Stöhr, Darren E R Waburton, Kristin L Campbell
PURPOSE: In rodents, a single exercise bout performed 24 h prior to a single doxorubicin treatment provides cardio-protection. This study investigated whether performing this intervention prior to every doxorubicin treatment for breast cancer reduced subclinical cardiotoxicity and treatment symptoms. METHODS: Twenty-four women with early stage breast cancer were randomly assigned to perform a 30-min, vigorous-intensity treadmill bout 24 h prior to each of four doxorubicin-containing chemotherapy treatments or to usual care...
November 6, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29103255/-two-cases-of-urachal-carcinoma-treated-by-ts-1-cddp-as-adjuvant-chemotherapy
#11
Michinobu Ozawa, Akito Kuromoto, Kento Morozumi, Masahiko Satou, Senji Hoshi, Kenji Numahata
Case 1 : A 48-year-old man presenting with gross hematuria was suspected to have a tumor located in the bladder dome. He was referred to our department for further examination and treatment. Cystoscopy showed a dome-shaped mass in the supravesical region. Computed tomography and magnetic resonance imaging indicated the possibility of urachal carcinoma and peritoneal dissemination. Therefore, partial cystectomy with urachal resection was performed. The intraoperative findings were disseminated peritoneal nodules and mucus entering the peritoneal cavity from the tumor...
October 2017: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/29080061/perceived-cognitive-impairment-in-people-with-colorectal-cancer-who-do-and-do-not-receive-chemotherapy
#12
Haryana M Dhillon, Ian F Tannock, Gregory R Pond, Corrinne Renton, Sean B Rourke, Janette L Vardy
PURPOSE: Cognitive symptoms are common after cancer, but poorly associated with neuropsychological results. We previously reported colorectal cancer (CRC) patients had more cognitive impairment than controls. Here, we explore relationships between cognitive symptoms and neuropsychological domains. METHODS: Subjects with CRC (N = 362) and 72 healthy controls completed neuropsychological assessments and Functional Assessment of Cancer Therapy-Cognition (FACT-COG) at baseline (pre-chemotherapy) and 6, 12, and 24 months...
October 27, 2017: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/29077931/supportive-care-needs-and-psychological-distress-and-or-quality-of-life-in-ambulatory-advanced-colorectal-cancer-patients-receiving-chemotherapy-a-cross-sectional-study
#13
Nobuhiro Sakamoto, Shuji Takiguchi, Hirokazu Komatsu, Toru Okuyama, Tomohiro Nakaguchi, Yosuke Kubota, Yoshinori Ito, Koji Sugano, Makoto Wada, Tatsuo Akechi
Background: Although currently many advanced colorectal cancer patients continuously receive chemotherapy, there are very few findings with regard to the supportive care needs of such patients. Methods: The purposes of this study were to investigate the patients' perceived needs and the association with psychological distress and/or quality of life, and to clarify the characteristics of patients with a high degree of unmet needs. Ambulatory colorectal cancer patients who were receiving chemotherapy were asked to complete the Short-Form Supportive Care Needs Survey questionnaire, which covers five domains of need (health system and information, psychological, physical, care and support, and sexuality needs), the Hospital Anxiety and Depression Scale and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire...
October 25, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29072421/anxiety-depression-and-quality-of-life-in-breast-cancer-patients-in-the-levant
#14
Reem Akel, Haidar El Darsa, Bilal Anouti, Deborah Mukherji, Sally Temraz, Rasha Raslan, Arafat Tfayli, Hazem Assi
Background: Limited data are currently available regarding the psychological well-being and quality of life of breast cancer patients after active treatment in Lebanon and the Arab region in general. The objective of this study was to determine the prevalence of anxiety and depression among Arab breast cancer patients and assess the quality of life with reference to socio-demographic and clinical characteristics. Methods: This cross-sectional study was conducted among female breast cancer patients diagnosed between January 2009 and March 2014, who were recruited from the outpatient clinics of Naef K...
October 26, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29057261/aprepitant-for-the-treatment-of-chronic-refractory-pruritus
#15
REVIEW
Alice He, Jihad M Alhariri, Ronald J Sweren, Madan M Kwatra, Shawn G Kwatra
Chronic pruritus is a difficult condition to treat and is associated with several comorbidities, including insomnia, depression, and decreased quality of life. Treatment for chronic itch includes corticosteroids, antihistamines, and systemic therapies such as naltrexone, gabapentin, UV light therapy, and immunomodulatory treatments, including azathioprine, methotrexate, and cellcept. However, some patients still remain refractory to conventional therapy. Aprepitant is a neurokinin-1 receptor antagonist approved for the prevention of chemotherapy-induced and postoperative nausea and vomiting (CINV, PONV)...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29056150/substance-p-and-the-neurokinin-1-receptor-the-new-crf
#16
Jesse R Schank, Markus Heilig
Substance P (SP) is an 11-amino acid neuropeptide of the tachykinin family that preferentially activates the neurokinin-1 receptor (NK1R). First isolated 85 years ago and sequenced 40 years later, SP has been extensively studied. Early studies identified a role for SP and the NK1R in contraction of intestinal smooth muscle, central pain processing, and neurogenic inflammation. An FDA-approved NK1R antagonist, aprepitant, is used clinically for the treatment of chemotherapy-induced nausea, as the NK1R influences the activity of the brain stem emesis centers...
2017: International Review of Neurobiology
https://www.readbyqxmd.com/read/29055062/cognition-quality-of-life-and-symptom-clusters-in-breast-cancer-using-bayesian-networks-to-elucidate-complex-relationships
#17
Selene Xu, Wesley Thompson, Sonia Ancoli-Israel, Lianqi Liu, Barton Palmer, Loki Natarajan
OBJECTIVE: Breast cancer patients frequently complain of cognitive dysfunction during chemotherapy. Patients also report experiencing a cluster of sleep problems, fatigue and depressive symptoms during chemotherapy. We aimed to understand the complex dynamic interrelationships of depression, fatigue, and sleep to ultimately elucidate their role in cognitive performance and quality of life among breast cancer survivors undergoing chemotherapy treatment. METHODS: Our study sample comprised 74 newly diagnosed stage I-III breast cancer patients scheduled to receive chemotherapy, and followed them for one year...
October 20, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/29045267/the-prevalence-and-investigation-of-risk-factors-of-oral-mucositis-in-a-pediatric-oncology-inpatient-population-a-prospective-study
#18
Gabrielle Allen, Richard Logan, Tom Revesz, Dorothy Keefe, Sam Gue
BACKGROUND: Oral mucositis can be a frequent and severe complication of chemotherapy in children. It can result in pain, infection, depression, prolonged admission, treatment delays, increase in patient morbidity, and increased costs. AIM: To record the prevalence and severity of oral mucositis among inpatients and explore the relationship of risks factors and the development of oral mucositis. DESIGN: During an 18-month period 643 clinical inpatient assessments were completed on 73 children who were admitted and had received chemotherapy in the last 14 days...
October 17, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29037071/evidence-based-review-of-biobran-mgn-3-arabinoxylan-compound-as-a-complementary-therapy-for-conventional-cancer-treatment
#19
Soo Liang Ooi, Debbie McMullen, Terry Golombick, Dipl Nut, Sok Cheon Pak
INTRODUCTION: Conventional cancer treatment, including surgery, chemotherapy, and radiotherapy, may not be sufficient to eradicate all malignant cells and prevent recurrence. Intensive treatment often leads to a depressed immune system, drug resistance, and toxicity, hampering the treatment outcomes. BioBran/MGN-3 Arabinoxylan is a standardized arabinoxylan concentrate which has been proposed as a plant-based immunomodulator that can restore the tumor-induced disturbance of the natural immune system, including natural killer cell activity to fight cancer, complementing conventional therapies...
October 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/29031318/symptom-clustering-and-quality-of-life-in-patients-with-ovarian-cancer-undergoing-chemotherapy
#20
Ju-Hee Nho, Sung Reul Kim, Joo-Hyun Nam
PURPOSE: The symptom clusters in patients with ovarian cancer undergoing chemotherapy have not been well evaluated. We investigated the symptom clusters and effects of symptom clusters on the quality of life of patients with ovarian cancer. METHOD: We recruited 210 ovarian cancer patients being treated with chemotherapy and used a descriptive cross-sectional study design to collect information on their symptoms. To determine inter-relationships among symptoms, a principal component analysis with varimax rotation was performed based on the patient's symptoms (fatigue, pain, sleep disturbance, chemotherapy-induced peripheral neuropathy, anxiety, depression, and sexual dysfunction)...
October 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
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