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https://www.readbyqxmd.com/read/29777621/serum-high-density-lipoprotein-cholesterol-is-a-protective-predictor-of-executive-function-in-older-patients-with-diabetes-mellitus
#1
Yue Sun, Jenny Lee, Ronald C Ma, Timothy Kwok
INTRODUCTION: Older people with diabetes mellitus (DM) are at high risk for cognitive impairment or dementia. The clinical predictors for cognitive decline in older people with DM were elucidated. METHODS: This was a secondary analysis of a vitamin B12 intervention trial in older people with DM. 271 non-demented subjects were followed up at nine months interval for 27 months. We explored the association between baseline clinical features with changes in cognitive measures (clinical dementia rating scale, neuropsychological test battery including executive function z scores, psychomotor speed z scores and memory z scores)...
May 19, 2018: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/29777549/frailty-risk-in-hospitalized-older-adults-with-and-without-diabetes-mellitus
#2
Deborah A Lekan, Thomas P McCoy
BACKGROUND: Research indicates that diabetes mellitus (DM) may be a risk factor for frailty and individuals with DM are more likely to be frail than individuals without DM, however, there is limited research in hospitalized older adults. OBJECTIVES: To determine the extent of frailty in hospitalized older adults with and without DM using a 16-item Frailty Risk Score (FRS) and assess the role of frailty in predicting 30-day rehospitalization, discharge to an institution, and in-hospital mortality...
May 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29777369/adherence-to-special-diets-and-its-association-with-meeting-the-nutrient-recommendations-in-individuals-with-type-1-diabetes
#3
A J Ahola, C Forsblom, Per-Henrik Groop
AIMS: Not much is known about adherence to special diets in type 1 diabetes, characteristics of individuals with special diets, and whether such practices should raise concerns with respect to meeting the dietary recommendations. In this study, we assessed the frequencies of adherence to special diets, in a population of individuals with type 1 diabetes, and investigated the association between special diet adherence and dietary intake, measured as dietary patterns and nutrient intakes...
May 18, 2018: Acta Diabetologica
https://www.readbyqxmd.com/read/29777153/depression-and-diabetes-distress-in-adults-with-type-2-diabetes-results-from-the-australian-national-diabetes-audit-anda-2016
#4
Natalie Nanayakkara, Anthony Pease, Sanjeeva Ranasinha, Natalie Wischer, Sofianos Andrikopoulos, Jane Speight, Barbora de Courten, Sophia Zoungas
This study explores the prevalence of, and factors associated with, likely depression and diabetes distress in adults with type 2 diabetes in a large, national sample. Australian National Diabetes Audit data were analysed from adults with type 2 diabetes attending 50 diabetes centres. The Brief Case find for Depression and Diabetes Distress Score 17 were administered to screen for likely depression and diabetes-related distress, respectively. A total of 2,552 adults with type 2 diabetes participated: (mean ± SD) age was 63 ± 13 years, diabetes duration was 12 ± 10 years, and HbA1c was 8 ± 2%...
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29776663/barriers-and-facilitators-to-diabetes-self-management-in-a-primary-care-setting-patient-perspectives
#5
Rahul Khairnar, Khalid M Kamal, Vincent Giannetti, Nilanjana Dwibedi, Jamie McConaha
BACKGROUND: Diabetes self-management (DSM) is a key element in the overall management of type-2 diabetes (T2DM). Identifying barriers and facilitators to DSM and addressing them is a critical step in achieving improved health outcomes in this population. OBJECTIVE: To assess patient reported barriers and facilitators to self-management of T2DM in a primary care setting. METHODS: This cross sectional study combined patient survey data with electronic medical record (EMR) data...
May 9, 2018: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/29775747/mediterranean-diet-and-depression-among-older-individuals-the-multinational-medis-study
#6
Maria F Masana, Josep Maria Haro, Anargiros Mariolis, Suzanne Piscopo, Giuseppe Valacchi, Vassiliki Bountziouka, Foteini Anastasiou, Akis Zeimbekis, Dimitra Tyrovola, Efthimios Gotsis, George Metallinos, Anna Polystipioti, Josep-Antoni Tur, Antonia-Leda Matalas, Christos Lionis, Evangelos Polychronopoulos, Labros S Sidossis, Stefanos Tyrovolas, Demosthenes B Panagiotakos
BACKGROUND: Depression has been linked to a large and growing economic and societal burden worldwide. In Europe, depression is one of the most frequent mental disorders across all age groups, but particularly in people aged 65 years and over, and higher depressive symptoms have been reported among individuals with chronic diseases (e.g., diabetes and heart disease). AIM: To evaluate the role of adherence to the Mediterranean diet (MedDiet) in depression in a sample of older people living in the Mediterranean basin...
May 15, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29774878/-etiology-and-risk-factors-for-meningitis-and-or-bacteremia-after-craniotomy-for-patients-with-glioma
#7
Yaning Wang, Yu Wang, Wenbin Ma
To evaluate the incidence and microbiological profile of meningitis and/or bacteremia after craniotomy in patients with glioma and analyze the risk factors relevant to postoperative meningitis.
 Methods: All demographic data, etiological data and clinical data for hospitalized patients who underwent craniotomy in Dept. of Neurosurgery of Peking Union Medical College Hospital between Jan. 2013 to Dec. 2017 were recorded.
 Results: The incidence of post-craniotomy meningitiswas 7.73%, bacteremia was 2.21% and meningitis combined with bacteremia was 1...
April 28, 2018: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/29773940/effects-of-social-support-network-size-on-mortality-risk-considerations-by-diabetes-status
#8
Paul D Loprinzi, M Allison Ford
Objective: Previous work demonstrates that social support is inversely associated with mortality risk. Less research, however, has examined the effects of the size of the social support network on mortality risk among those with and without diabetes, which was the purpose of this study. Methods: Data from the 1999-2008 National Health and Nutrition Examination Survey were used, with participants followed through 2011. This study included 1,412 older adults (≥60 years of age) with diabetes and 5,872 older adults without diabetes...
May 2018: Diabetes Spectrum: a Publication of the American Diabetes Association
https://www.readbyqxmd.com/read/29772286/prevalence-of-gestational-diabetes-and-subsequent-type-2-diabetes-among-u-s-women
#9
Sarah Stark Casagrande, Barbara Linder, Catherine C Cowie
AIMS: The true prevalence of gestational diabetes (GDM) in the United States is unknown. This study determined the prevalence of GDM and a subsequent diagnosis of diabetes in a nationally representative sample of U.S. women. METHODS: The crude and age-adjusted prevalence of GDM and subsequent diabetes were evaluated by sociodemographic and health-related characteristics among women age ≥20 years in the National Health and Nutrition Examination Surveys, 2007-2014 (N=8,185)...
May 14, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29771178/islet-microvasculature-alterations-with-loss-of-beta-cells-in-patients-with-type-1-diabetes
#10
Joseph S Canzano, Lith H Nasif, Elizabeth A Butterworth, Dongtao A Fu, Mark A Atkinson, Martha Campbell-Thompson
Islet microvasculature provides key architectural and functional roles, yet the morphological features of islets from patients with type 1 diabetes are poorly defined. We examined islet and exocrine microvasculature networks by multiplex immunofluorescence imaging of pancreases from organ donors with and without type 1 diabetes ( n=17 and n=16, respectively) and determined vessel diameter, density, and area. We also analyzed these variables in insulin-positive and insulin-negative islets of 7 type 1 diabetes donors...
May 1, 2018: Journal of Histochemistry and Cytochemistry: Official Journal of the Histochemistry Society
https://www.readbyqxmd.com/read/29770600/how-does-glucagon-like-peptide-1-stimulate-human-%C3%AE-cell-proliferation-a-lesson-from-islet-graft-experiments
#11
Yoshio Fujitani
The incidence of type 2 diabetes increases with age. The age-dependent decline in functional β-cell mass contributes to the increased risk of onset of diabetes, reflecting the central role of pancreatic β cells in glucose homeostasis. Indeed, the replication rate of human and rodent β cells is known to decline sharply with age, and such a characteristic of β cells may explain the increased onset of type 2 diabetes in the older population. The molecular mechanism involved in the age-dependent decline of β-cell proliferation has been extensively studied, mainly using rodents and in vitro culture systems, but its molecular basis is still largely unknown...
May 16, 2018: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/29769503/vitamin-d-status-in-newly-diagnosed-type-2-diabetes-patients-attending-in-a-tertiary-hospital-of-bangladesh
#12
M S Alam, M Kamrul-Hasan, S T Kalam, S Selim, F Akter, M Saifuddin
Vitamin D deficiency is common in patients with type 2 diabetes mellitus (T2DM). Vitamin D status may have a causal role in the onset of T2DM and may influence glycaemic control in these patients. However, data on vitamin D status among Bangladeshi T2DM patients are scarce. The present cross-sectional study was done among newly diagnosed 50 T2DM patients attending outpatient department of Comilla Diabetic Hospital, Bangladesh to address this lacuna. Serum 25(OH)D was measured in all and classified as normal (≥30ng/mL), insufficient (>20 to 29...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29768620/association-between-chronic-diseases-and-handgrip-strength-in-older-adults-residents-of-florian%C3%A3-polis-sc-brazil
#13
Susana Cararo Confortin, Ana Lúcia Danielewicz, Danielle Ledur Antes, Lariane Mortean Ono, Eleonora d'Orsi, Aline Rodrigues Barbosa
This paper aims to verify the association between chronic diseases and handgrip strength (HS) in the older adults of Florianópolis, SC. This is a cross-sectional analysis of a longitudinal population-based study. HS was measured by dynamometer. Independent variables included 10 chronic diseases and falls. Simple and multiple linear regression analyses were performed. In the final model, in women, arthritis/rheumatism/arthrosis (β: -1.27; 95%CI: -2.55; -0.20) was associated with lower HS and bronchitis/ asthma (β: 1...
May 2018: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/29768089/a-commentary-on-effects-of-regular-physical-activity-on-the-cognitive-performance-of-type-2-diabetic-patients-a-systematic-review-by-podolski-et-al-metab-syndr-relat-disord-2017-15-481-493
#14
Erin M Shellington, Sonja M Reichert, Robert J Petrella
Type 2 diabetes mellitus (T2DM) imparts an increased risk for cognitive decline, specifically executive function, which is important to maintain for diabetes self-management. There is evidence to suggest that exercise improves cognition in healthy older adults; however, the literature in adults with T2DM is lacking. This commentary is in complement to Podolski et al.'s systematic review evaluating the effects of physical activity on cognitive function in adults with T2DM. We have included eight additional studies and further highlight their conclusions on the heterogeneity of the literature thus far...
May 16, 2018: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/29767246/dnajc3-mutation-in-thai-familial-type-2-diabetes-mellitus
#15
Sirikul Kulanuwat, Watip Tangjittipokin, Prapaporn Jungtrakoon, Chutima Chanprasert, Jatuporn Sujjitjoon, Ninareeman Binnima, Pa-Thai Yenchitsomanus, Nattachet Plengvidhya
Type 2 diabetes mellitus (T2D) is a heterogeneous disease, with certain cases presenting an autosomal dominant type. The rare coding variants of disease‑causing genes in T2D remain mostly unclear. The present study aimed to identify the disease‑causing gene conducting whole exome sequencing in a Thai T2D family with an autosomal dominant transmission of T2D with no evidence of mutations in known maturity‑onset diabetes of the young (MODY) genes. Candidate variants were selected according to certain criteria of mutation prediction programs, followed by segregation analysis with diabetes in the family...
May 14, 2018: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29765224/statins-use-and-risk-of-new-onset-diabetes-in-hypertensive-patients-a-population-based-retrospective-cohort-study-in-yinzhou-district-ningbo-city-people-s-republic-of-china
#16
Hailong Li, Hongbo Lin, Houyu Zhao, Yang Xu, Yinchu Cheng, Peng Shen, Siyan Zhan
Background: Reports have suggested that statin use is associated with an increased incidence of type 2 diabetes mellitus (T2DM). Guidelines suggested that statins should be prescribed in hypertensive patients for primary prevention. However, there were very few studies on the risk of T2DM associated with statin use among patients with hypertension in mainland People's Republic of China. Purpose: To determine the association between statin use and new-onset diabetes mellitus among patients with hypertension in mainland People's Republic of China...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29765104/falls-and-recurrent-falls-among-adults-in-a-multi-ethnic-asian-population-the-singapore-epidemiology-of-eye-diseases-study
#17
Wei Dai, Yih-Chung Tham, Miao-Li Chee, Nicholas Y Q Tan, Kah-Hie Wong, Shivani Majithia, Charumathi Sabanayagam, Ecosse Lamoureux, Tien-Yin Wong, Ching-Yu Cheng
We evaluated the rate and risk factors associated with falls and recurrent falls in a multi-ethnic Asian population. 10,009 participants aged ≥40 years (mean[SD] age = 58.9[10.4] years) underwent clinical examinations and completed interviewer-administered questionnaires. Participants who self-reported at least one fall or ≥2 falls in past 12 months were defined as fallers and recurrent fallers, respectively. Age-standardized rates for falls and recurrent falls were 13.8% (95%CI, 13.1-14.6%) and 4.6% (95%CI, 4...
May 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29764429/health-and-quality-of-life-outcomes-impairment-of-quality-of-life-in-type-2-diabetes-mellitus-a-cross-sectional-study
#18
Jessie N Zurita-Cruz, Leticia Manuel-Apolinar, María Luisa Arellano-Flores, Alejandro Gutierrez-Gonzalez, Alma Gloria Najera-Ahumada, Nelly Cisneros-González
BACKGROUND: Type 2 diabetes mellitus (DM2) is a chronic disease, and for treatment to succeed, it is necessary to harmonize the mental health of the patient with the environment, which impacts quality of life and adherence to medical regimens. The objetive of this study is describe the quality of life of patients with DM2 and the factors relates to its modification. METHODS: This investigation was a cross-sectional study. Patients over 18 years of age with DM2 were selected...
May 15, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29764380/osteoporosis-diabetes-and-hypertension-are-major-risk-factors-for-mortality-in-older-adults-an-intermediate-report-on-a-prospective-survey-of-1467-community-dwelling-elderly-healthy-pensioners-in-switzerland
#19
Jean-Pierre Gutzwiller, Jean-Pierre Richterich, Zeno Stanga, Urs E Nydegger, Lorenz Risch, Martin Risch
BACKGROUND: Osteoporosis is an important morbidity factor for ageing populations in developed countries. However, compared to the amount of information available on diabetes and cardiovascular disease, little is known about the direct impact of osteoporosis on general mortality in older age. METHODS: We obtained data from a prospective population-based cohort of pensioners from the SENIORLAB study who were subjectively healthy. The inclusion criteria were an age of at least 60 years and Swiss residence...
May 15, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29763911/clinical-correlates-of-ambulatory-blood-pressure-phenotypes-at-a-tertiary-care-hospital-in-turkey
#20
Siyar Erdogmus, Sim Kutlay, Zeynep Kendi Celebi, Tolga Aydın, Damla Ors Sendogan, Gizem Kumru, Kenan Keven, Gokhan Nergizoglu, Sehsuvar Erturk, Sule Sengul
BACKGROUND/AIMS: Hypertension and its complications are major public health issues worldwide due to their association with high cardiovascular morbidity and mortality. Despite significant progress in health, the prevalence of hypertension is increasing. Ambulatory blood pressure monitoring (ABPM) is becoming increasingly important for the management of hypertension. In this study, we aimed to investigate the clinical and laboratory correlates of ambulatory blood pressure (ABP) phenotypes at a tertiary care hospital in Turkey...
May 10, 2018: Kidney & Blood Pressure Research
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