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https://www.readbyqxmd.com/read/28214141/feasibility-and-safety-of-same-day-discharge-after-complex-percutaneous-coronary-intervention-using-forearm-approach
#1
Michael Koutouzis, Aris Karatasakis, Emmanouil S Brilakis, Maria Agelaki, Christos Maniotis, Panagiotis Dimitriou, Efstathios Lazaris
OBJECTIVES: We sought to assess the feasibility and safety of same-day discharge (SDD) after complex percutaneous coronary intervention (PCI) using a forearm approach. BACKGROUND: SDD has been shown to be safe after elective, low-risk PCI. However, the feasibility and safety of SDD in more complex patients and lesions has received limited study. METHODS: We retrospectively reviewed 1190 elective PCIs that were performed between January 2013 and December 2015 at the Red Cross General Hospital...
February 8, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28212639/erectile-dysfunction-and-exposure-to-ambient-air-pollution-in-a-nationally-representative-cohort-of-older-men
#2
Lindsay A Tallon, Justin Manjourides, Vivian C Pun, Murray A Mittleman, Marianthi-Anna Kioumourtzoglou, Brent Coull, Helen Suh
BACKGROUND: Little is known about the association between air pollution and erectile dysfunction (ED), a disorder occurring in 64% of men over the age of 70, and to date, no studies have been published. To address this significant knowledge gap, we explored the relationship between ED and air pollution in a group of older men who were part of the National Social Life, Health, and Aging Project (NSHAP), a nationally representative cohort study of older Americans. METHODS: We obtained incident ED status and participant data for 412 men (age 57-85)...
February 17, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28212629/cardiometabolic-risk-in-a-population-of-older-adults-with-multiple-co-morbidities-in-rural-south-africa-the-haalsi-health-and-aging-in-africa-longitudinal-studies-of-indepth-communities-study
#3
Thomas A Gaziano, Shafika Abrahams-Gessel, F Xavier Gomez-Olive, Alisha Wade, Nigel J Crowther, Sartaj Alam, Jennifer Manne-Goehler, Chodziwadziwa W Kabudula, Ryan Wagner, Julia Rohr, Livia Montana, Kathleen Kahn, Till W Bärnighausen, Lisa F Berkman, Stephen Tollman
BACKGROUND: A consequence of the widespread uptake of anti-retroviral therapy (ART) is that the older South African population will experience an increase in life expectancy, increasing their risk for cardiometabolic diseases (CMD), and its risk factors. The long-term interactions between HIV infection, treatment, and CMD remain to be elucidated in the African population. The HAALSI cohort was established to investigate the impact of these interactions on CMD morbidity and mortality among middle-aged and older adults...
February 17, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28212619/brain-and-liver-pathology-amyloid-deposition-and-interferon-responses-among-older-hiv-positive-patients-in-the-late-haart-era
#4
Isaac H Solomon, Umberto De Girolami, Sukrutha Chettimada, Vikas Misra, Elyse J Singer, Dana Gabuzda
BACKGROUND: HIV+ patients on highly active antiretroviral therapy (HAART) with suppressed viral loads have a low incidence of HIV-associated dementia, but increased prevalence of milder forms of HIV-associated neurocognitive disorders (HAND). These milder forms of HAND are often associated with minimal histological abnormalities, and their pathophysiology is unclear. Comorbidities, altered amyloid metabolism, accelerated brain aging, and activated interferon responses are suspected to play a role in HAND pathogenesis in HAART-treated persons...
February 17, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28212407/epidemiology-of-low-proteinuric-chronic-kidney-disease-in-renal-clinics
#5
Luca De Nicola, Michele Provenzano, Paolo Chiodini, Silvio Borrelli, Luigi Russo, Antonio Bellasi, Domenico Santoro, Giuseppe Conte, Roberto Minutolo
CKD patients with low-grade proteinuria (LP) are common in nephrology clinics. However, prevalence, characteristics, and the competing risks of ESRD and death as the specific determinants, are still unknown. We analyzed epidemiological features of LP status in a prospective cohort of 2,340 patients with CKD stage III-V referred from ≥6 months in 40 nephrology clinics in Italy. LP status was defined as proteinuria <0.5 g/24h according to current KDIGO guidelines. Patients with higher proteinuria constituted the control group (CON)...
2017: PloS One
https://www.readbyqxmd.com/read/28210539/participation-in-preventive-health-check-ups-among-19-351-women-in-germany
#6
Stefanie Schülein, Katherine J Taylor, Dirk Schriefer, Maria Blettner, Stefanie J Klug
In Germany, a biennial preventive health check-up has been available for individuals aged 35 and older since 1989. The check-up includes identification of cardiovascular disease risk factors and examinations for diabetes mellitus type 2 and kidney disease. Participation in preventive health check-ups among 19,351 women aged 35 to 74 in Germany in 2004 was investigated. Logistic regression was performed to examine associations between participation and age, marital status, education, socio-economic status (SES) and region of residence...
June 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/28209549/factors-affecting-consultation-length-in-a-japanese-diabetes-practice
#7
Yusuke Kabeya, Junko Uchida, Masao Toyoda, Takeshi Katsuki, Yoichi Oikawa, Kiyoe Kato, Toshihide Kawai, Akira Shimada, Yoshihito Atsumi, Megumu Higaki
AIMS: Sufficient consultation time is important for establishing good doctor-patient relationship. We examined the factors that affect consultation length in Japanese diabetes practice. METHODS: This was a cross-sectional study performed at a diabetes clinic in central Tokyo, Japan. Regular diabetes consultations of 1197 patients with 22 physicians were analyzed. Consultation time and clinical characteristics were obtained from the electronic records. A negative binomial model, which included patient and physician characteristics, was constructed to examine the association of the variables with consultation length...
January 29, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28209453/-detection-and-classification-of-chronic-kidney-disease-in-primary-care-and-importance-of-albuminuria
#8
P J Labrador, S González-Sanchidrián, S Polanco, E Davin, J M Fuentes, J R Gómez-Martino
INTRODUCTION: Chronic kidney disease (CKD) is a public health problem, and Primary Care (PC) plays a key role in its detection and classification based on estimated glomerular filtration rate (eGFR), as well as the level of albuminuria for its proper management. The aim of this study was to analyse the prevalence and classification of CKD in patients attended in PC. MATERIAL AND METHODS: An analysis was made of CKD prevalence and classification according to the Kidney Disease-Improving Global Outcomes guidelines in PC patients...
February 13, 2017: Semergen
https://www.readbyqxmd.com/read/28208207/-spatial-distribution-of-type-2-diabetes-mellitus-in-berlin-application-of-a-geographically-weighted-regression-analysis-to-identify-location-specific-risk-groups
#9
Boris Kauhl, Jonas Pieper, Jürgen Schweikart, Andrea Keste, Marita Moskwyn
Understanding which population groups in which locations are at higher risk for type 2 diabetes mellitus (T2DM) allows efficient and cost-effective interventions targeting these risk-populations in great need in specific locations. The goal of this study was to analyze the spatial distribution of T2DM and to identify the location-specific, population-based risk factors using global and local spatial regression models. To display the spatial heterogeneity of T2DM, bivariate kernel density estimation was applied...
February 16, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/28208044/daily-step-count-and-the-need-for-hospital-care-in-subsequent-years-in-a-community-based-sample-of-older-australians
#10
Ben D Ewald, Christopher Oldmeadow, John R Attia
OBJECTIVES: To determine the extent to which physical activity reduces the number of hospital bed-days for Australians over 55, using an objective measure of activity. DESIGN, SETTING AND PARTICIPANTS: 9784 Newcastle residents aged 55 years or more were invited to participate. 3253 responders were eligible and wore pedometers for one week during 2005-2007; their hospital data from recruitment to 31 March 2015 were analysed (mean follow-up time: 8.2 years). Complete data for 2110 people were available for analysis...
February 20, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/28207538/comparison-of-baseline-characteristics-and-clinical-course-in-japanese-patients-with-type-2-diabetes-among-whom-different-types-of-oral-hypoglycemic-agents-were-chosen-by-diabetes-specialists-as-initial-monotherapy-jddm-42
#11
Kazuya Fujihara, Risa Igarashi, Satoshi Matsunaga, Yasuhiro Matsubayashi, Takaho Yamada, Hiroki Yokoyama, Shiro Tanaka, Hitoshi Shimano, Hiroshi Maegawa, Katsuya Yamazaki, Koichi Kawai, Hirohito Sone
Little is known about the relationships between patient factors and the antihyperglycemic agents that have been prescribed as initial therapy by diabetes specialists for patients with type 2 diabetes. Moreover, there has been little clarification of the subsequent usage patterns and related factors that influenced the continuation or discontinuation of the drug or the addition of another drug. To provide information on these issues, we evaluated the clinical characteristics of Japanese patients with type 2 diabetes for whom different types of oral hypoglycemic agents (i...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28207331/a-systematic-review-of-cardiovascular-disease-in-sexual-minorities
#12
Billy A Caceres, Abraham Brody, Rachel E Luscombe, Jillian E Primiano, Peter Marusca, Edward M Sitts, Deborah Chyun
BACKGROUND: Mental health and HIV disparities are well documented among sexual minorities, but there is a dearth of research on other chronic conditions. Cardiovascular disease remains the leading cause of death worldwide. Although sexual minorities have high rates of several modifiable risk factors for cardiovascular disease (including stress, tobacco use, and alcohol consumption), there is a paucity of research in this area. OBJECTIVES: In this systematic review, we synthesized and critiqued the existing evidence on cardiovascular disease among sexual minority adults...
February 16, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28206976/lipid-and-alzheimer-s-disease-genes-associated-with-healthy-aging-and-longevity-in-healthy-oldest-old
#13
Lauren C Tindale, Stephen Leach, John J Spinelli, Angela R Brooks-Wilson
Several studies have found that long-lived individuals do not appear to carry lower numbers of common disease-associated variants than ordinary people; it has been hypothesized that they may instead carry protective variants. An intriguing type of protective variant is buffering variants that protect against variants that have deleterious effects. We genotyped 18 variants in 15 genes related to longevity or healthy aging that had been previously reported as having a gene-gene interaction or buffering effect...
February 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28202888/sarcopenia-and-its-relationship-with-falling-among-outpatients-attending-a-geriatric-and-memory-clinic-at-kyorin-university-hospital
#14
Masamichi Tanaka, Kumiko Nagai, Hitomi Koshiba, Toshifumi Matui, Koichi Kozaki
AIM: The aim of the present study was to investigate the prevalence of sarcopenia in outpatients attending a geriatric and memory clinic and to investigate its relationship with falling. METHODS: We investigated the prevalence of sarcopenia (according to the EWGSOP criteria) among 283 outpatients that were all ≥65 years of age, and who attended the geriatric and memory clinic at Kyorin University Hospital. We also examined comorbidities, CGA items, and fall-related measures, and analyzed the relationships between these factors and sarcopenia...
2017: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
https://www.readbyqxmd.com/read/28202550/excess-bmi-in-childhood-a-modifiable-risk-factor-for-type-1-diabetes-development
#15
Christine Therese Ferrara, Susan Michelle Geyer, Yuk-Fun Liu, Carmella Evans-Molina, Ingrid M Libman, Rachel Besser, Dorothy J Becker, Henry Rodriguez, Antoinette Moran, Stephen E Gitelman, Maria J Redondo
OBJECTIVE: We aimed to determine the effect of elevated BMI over time on the progression to type 1 diabetes in youth. RESEARCH DESIGN AND METHODS: We studied 1,117 children in the TrialNet Pathway to Prevention cohort (autoantibody-positive relatives of patients with type 1 diabetes). Longitudinally accumulated BMI above the 85th age- and sex-adjusted percentile generated a cumulative excess BMI (ceBMI) index. Recursive partitioning and multivariate analyses yielded sex- and age- specific ceBMI thresholds for greatest type 1 diabetes risk...
February 15, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28202216/lifestyle-and-health-determinants-of-cardiovascular-disease-among-greek-older-adults-living-in-eastern-aegean-islands-an-adventure-within-the-medis-study
#16
Alexandra Foscolou, Evangelos Polychronopoulos, Efstratia Paka, Stefanos Tyrovolas, Vassiliki Bountziouka, Akis Zeimbekis, Dimitra Tyrovola, Dilek Ural, Demosthenes Panagiotakos
OBJECTIVE: The aim of the present study was to evaluate lifestyle and health determinants of cardiovascular disease (CVD) risk among Greek elderly residents living in Eastern Aegean islands, in both Greece and Turkey. METHODS: Under the context of the MEDIS study, 724 older adults (aged 65 to 100 years) from 8 Eastern Aegean Sea Greek islands (n=100 living in Samothrace, 142 in Lesvos, 150 in Limnos, 76 in Ikaria, 52 in Kassos, 149 in Rhodes and Karpathos) and from Turkey (n=55older adults of Greek origin living on Gökçeada Island) were voluntarily recruited...
November 16, 2016: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/28198635/impact-of-comorbidities-by-age-on-symptom-presentation-for-suspected-acute-coronary-syndromes-in-the-emergency-department
#17
Larisa A Burke, Anne G Rosenfeld, Mohamud R Daya, Karen M Vuckovic, Jessica K Zegre-Hemsey, Maria Felix Diaz, Josemare Tosta Daiube Santos, Sahereh Mirzaei, Holli A DeVon
BACKGROUND: It is estimated half of acute coronary syndrome (ACS) patients have one or more associated comorbid conditions. AIMS: Aims were to: 1) examine the prevalence of comorbid conditions in patients presenting to the emergency department with symptoms suggestive of ACS; 2) determine if comorbid conditions influence ACS symptoms; and 3) determine if comorbid conditions predict the likelihood of receiving an ACS diagnosis. METHODS: A total of 1064 patients admitted to five emergency departments were enrolled in this prospective study...
February 1, 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28198091/impact-of-chronic-kidney-disease-on-2-year-clinical-outcomes-in-patients-treated-with-6-month-or-24-month-dapt-duration-an-analysis-from-the-prodigy-trial
#18
Giuseppe Gargiulo, Andrea Santucci, Raffaele Piccolo, Anna Franzone, Sara Ariotti, Andrea Baldo, Giovanni Esposito, Aris Moschovitis, Stephan Windecker, Marco Valgimigli
OBJECTIVES: To assess whether moderate-to-severe CKD is a treatment modifier for benefit or harm in patients randomly allocated to 24-month versus 6-month DAPT. BACKGROUND: It is still unclear whether chronic kidney disease CKD should impact on the decision-making on optimal duration of dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI). METHODS AND RESULTS: PRODIGY trial randomized 1970 all-comer patients at 24-month versus 6-month DAPT after PCI...
February 15, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28197645/subclinical-decrease-in-myocardial-function-in-asymptomatic-infants-of-diabetic-mothers-a-tissue-doppler-study
#19
Jenny E Zablah, Dorota Gruber, Guillaume Stoffels, Estefania G Cabezas, Denise A Hayes
Infants of diabetic mothers (IDMs) with hypertrophic cardiomyopathy are recognized to have impaired myocardial performance, but less is known about ventricular function in IDMs without hypertrophy. We hypothesized that in asymptomatic newborns with normal two-dimensional echocardiographic evaluations, pulsed wave tissue Doppler imaging (TDI) would suggest a subclinical decrease in the cardiac function of IDMs compared to infants of non-diabetics (nIDMs). This is a retrospective cohort study of asymptomatic neonates ≥36 weeks gestation, at 0-7 days of life, with normal standard echocardiograms...
February 14, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28197217/the-effect-of-demographics-and-patient-location-on-the-outcome-of-patients-with-acute-respiratory-distress-syndrome
#20
Haitham El-Haddad, Hyejeong Jang, Wei Chen, Samran Haider, Ayman O Soubani
OBJECTIVE: Outcome of acute respiratory distress syndrome (ARDS) in relation to age, gender, race, pre-Intensive Care Unit (ICU) location, and type of ICU. METHODS: Retrospective cohort study of patients enrolled in the ARDS network randomized controlled trials. RESULTS: A total of 2914 patients were included in these trials. Outcomes were adjusted to baseline covariates including APACHE III score, vasopressor use, cause of lung injury, lung injury score, diabetes, cancer status, body mass index, and study ID...
January 2017: Annals of Thoracic Medicine
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