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https://www.readbyqxmd.com/read/28930008/usutu-virus-rna-in-mosquitoes-israel-2014-2015
#1
Batya Mannasse, Ella Mendelson, Laor Orshan, Orna Mor, Uri Shalom, Tamar Yeger, Yaniv Lustig
We identified Usutu virus (USUV) RNA in 6 pools of mosquitoes trapped in northern Israel during 2014-2015. These Israeli strains were most similar to strains identified in Senegal and Germany, which further elucidates common ancestry and evolutionary dynamics of USUV. Our findings suggest that human infection with USUV might occur in Israel.
October 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28927961/clinical-and-electrophysiological-outcomes-of-deep-tms-over-the-medial-prefrontal-and-anterior-cingulate-cortices-in-ocd-patients
#2
Lior Carmi, Uri Alyagon, Noam Barnea-Ygael, Joseph Zohar, Reuven Dar, Abraham Zangen
BACKGROUND: Obsessive Compulsive Disorder (OCD) is a chronic and disabling disorder with poor response to pharmacological treatments. Converging evidences suggest that OCD patients suffer from dysfunction of the cortico-striato-thalamo-cortical (CSTC) circuit, including in the medial prefrontal cortex (mPFC) and the anterior cingulate cortex (ACC). OBJECTIVE: To examine whether modulation of mPFC-ACC activity by deep transcranial magnetic stimulation (DTMS) affects OCD symptoms...
September 6, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28922687/comparison-of-perioperative-renal-and-oncologic-outcomes-in-robotic-assisted-versus-open-partial-nephrectomy
#3
Jo-Lynn Tan, Mark Frydenberg, Jeremy Grummet, Uri Hanegbi, Ross Snow, Sarah Mann, Kirobel Begashaw, Daniel Moon
BACKGROUND: To compare perioperative, renal and oncological outcomes after robotic-assisted partial nephrectomy (RAPN) versus open partial nephrectomy (OPN) for the treatment of renal tumours. METHODS: All partial nephrectomies performed at a Metropolitan Urology Centre between 2010 and 2016 were analysed. Baseline data was collected for patient demographics, tumour characteristics (tumour size, laterality and polarity, RENAL scores), and perioperative variables (e...
September 18, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28920518/the-indirect-costs-of-underfunding-foreign-partners-in-global-health-research-a-case-study
#4
Johanna T Crane, Irene Andia Biraro, Tamer M Fouad, Yap Boum, David R Bangsberg
This study of a global health research partnership assesses how U.S. fiscal administrative policies impact capacity building at foreign partner institutions. We conducted a case study of a research collaboration between Mbarara University of Science and Technology (MUST) in Mbarara, Uganda, and originally the University of California San Francisco (UCSF), but now Massachusetts General Hospital (MGH). Our case study is based on three of the authors' experiences directing and working with this partnership from its inception in 2003 through 2015...
September 16, 2017: Global Public Health
https://www.readbyqxmd.com/read/28916201/targeting-heparanase-to-the-mammary-epithelium-enhances-mammary-gland-development-and-promotes-tumor-growth-and-metastasis
#5
Ilanit Boyango, Uri Barash, Liat Fux, Inna Naroditsky, Neta Ilan, Israel Vlodavsky
Heparanase is an endoglucuronidase that uniquely cleaves the heparan sulfate side chains of heparan sulfate proteoglycans. This activity ultimately alters the structural integrity of the ECM and basement membrane that becomes more prone to cellular invasion by metastatic cancer cells and cells of the immune system. In addition, enzymatically inactive heparanase was found to facilitate the proliferation and survival of cancer cells by activation of signaling molecules such as Akt, Src, signal transducer and activation of transcription (Stat), and epidermal growth factor receptor...
September 12, 2017: Matrix Biology: Journal of the International Society for Matrix Biology
https://www.readbyqxmd.com/read/28914235/jump-stabilization-and-landing-control-by-wing-spreading-of-a-locust-inspired-jumper
#6
Avishai Beck, Valentin Zaytsev, Uri Ben-Hanan, Gabor Kosa, Amir Ayali, Avi Weiss
Bio-inspired robotics is a promising design strategy for mobile robots. Jumping is an energy efficient locomotion gait for traversing difficult terrain. Inspired by the jumping and flying behavior of the desert locust, we have recently developed a miniature jumping robot that can jump over 3.5 m high. However, much like the non-adult locust, it rotates while in the air and lands uncontrollably. Inspired by the winged adult locust, we have added spreading wings and a tail to the jumper. After the robot leaps, at the apex of the trajectory, the wings unfold and it glides to the ground...
September 15, 2017: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/28905361/association-between-oral-health-and-upper-respiratory-tract-infection-among-children
#7
Ying Zhou, Shan Jiang, Kar Yan Li, Edward Chin Man Lo, Xiaoli Gao
BACKGROUND: The oral cavity is a potential reservoir for respiratory pathogens. This longitudinal study investigated the association between upper respiratory tract infection (URI) and oral health among children. METHODS: A total of 288 children aged 4 years were recruited. Their dental caries and oral hygiene status were clinically determined, using the dmft (decayed, missing and filled teeth) index and the Silness-Löe plaque index. Questionnaires were completed by parents to collect information on the child's socio-demographic background and URI episodes and symptoms in the following 12 months...
September 14, 2017: International Dental Journal
https://www.readbyqxmd.com/read/28904979/the-russians-are-the-fastest-in-marathon-cross-country-skiing-the-engadin-ski-marathon
#8
Pantelis Theodoros Nikolaidis, Jan Heller, Beat Knechtle
It is well known that athletes from a specific region or country are dominating certain sports disciplines such as marathon running or Ironman triathlon; however, little relevant information exists on cross-country skiing. Therefore, the aim of the present study was to investigate the aspect of region and nationality in one of the largest cross-country skiing marathons in Europe, the "Engadin Ski Marathon." All athletes (n = 197,125) who finished the "Engadin Ski Marathon" between 1998 and 2016 were considered...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28903669/the-evil-animal-a-terror-management-theory-perspective-on-the-human-tendency-to-kill-animals
#9
Uri Lifshin, Jeff Greenberg, Colin A Zestcott, Daniel Sullivan
This research tested whether support for the killing of animals serves a terror management function. In five studies, death primes caused participants to support the killing of animals more than control primes, unless the participants' self-esteem had been elevated (Study 4). This effect was not moderated by gender, preexisting attitudes toward killing animals or animal rights, perceived human-animal similarity, religiosity, political orientation, or by the degree to which the killing was justified. Support for killing animals after subliminal death primes was also associated with an increased sense of power and invulnerability (Study 5)...
June 2017: Personality & Social Psychology Bulletin
https://www.readbyqxmd.com/read/28903494/optimization-of-the-ocular-treatment-following-organophosphate-nerve-agent-insult
#10
Inbal Egoz, Uri Nili, Ettie Grauer, Ariel Gore
Eye exposure to organophosphate (OP) irreversible acetylcholinesterase inhibitors, results in long-term miosis and impaired visual function. The aim of this study was to find an anticholinergic antidote, which would counteract miosis and visual impairment induced by the nerve agents sarin and VX with minimal untoward side-effects. Rat pupil width and light reflex were evaluated from 15 min up to 2 weeks following topical OP exposure with or without topical ocular treatment of atropine or homatropine or with a combined intramuscular treatment of trimedoxime (TMB-4) and atropine (TA)...
September 1, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/28892513/placebo-can-enhance-creativity
#11
Liron Rozenkrantz, Avraham E Mayo, Tomer Ilan, Yuval Hart, Lior Noy, Uri Alon
BACKGROUND: The placebo effect is usually studied in clinical settings for decreasing negative symptoms such as pain, depression and anxiety. There is interest in exploring the placebo effect also outside the clinic, for enhancing positive aspects of performance or cognition. Several studies indicate that placebo can enhance cognitive abilities including memory, implicit learning and general knowledge. Here, we ask whether placebo can enhance creativity, an important aspect of human cognition...
2017: PloS One
https://www.readbyqxmd.com/read/28890229/patterns-of-emotion-regulation-and-emotion-related-behaviors-among-parents-of-children-with-and-without-adhd
#12
Vered Shenaar-Golan, Nava Wald, Uri Yatzkar
Parent emotion regulation is a crucial factor in child adjustment. This study examined the patterns and correlation of emotion regulation and emotion-related behaviors for parents of children with and without ADHD. The study emphasized specific parental emotion regulation strategies used in parent-child interactions. Of the 177 participating parents 55.4% had at least one child with ADHD. Participants were asked to complete questionnaires measuring their emotion regulation and emotion-related behaviors (supportive vs...
September 1, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28887290/individual-feedback-to-reduce-inappropriate-antimicrobial-prescriptions-for-treating-acute-upper-respiratory-tract-infections-in-an-outpatient-setting-of-a-thai-university-hospital
#13
Pinyo Rattanaumpawan, Nuttagarn Chuenchom, Visanu Thamlikitkul
BACKGROUND: Excessive antimicrobial use for acute Upper Respiratory InfectionBackground Excessive antimicrobial use for acute Upper Respiratory Infections (URIs) is one of the most common problems in clinical practice. Interventions are needed to reduce antimicrobial overuse in these common infections.s (URIs) is one of the most common problems in clinical practice. Interventions are needed to reduce antimicrobial overuse in these common infections. METHODS: During a 9-month study period (June 2014-February 2015), we conducted a quasi-experimental (pre/post) study among internal medicine residents and fellows in an outpatient setting of Siriraj Hospital, Thailand...
September 5, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28885955/comparison-of-clinical-features-in-a-population-of-basic-military-trainees-versus-the-general-department-of-defense-beneficiary-population-presenting-with-influenza
#14
H Samuel Scheuller, Jisuk Park, Lisa Lott, Michele Tavish, Patrick Danaher
INTRODUCTION: Upper respiratory tract infection (URI) is a well-documented cause of morbidity, extra expense, and lost training time among basic military trainees (BMTs). The goal of this study was to characterize the clinical presentation of influenza in the BMT population and to better understand how this presentation differs from that of the general Department of Defense (DoD) beneficiary population (non-BMTs). MATERIALS AND METHODS: Clinical and demographic data were collected in a prospective study that enrolled DoD beneficiaries presenting to medical treatment facilities in San Antonio, Texas, with URI symptoms between January 2005 and March 2011...
September 2017: Military Medicine
https://www.readbyqxmd.com/read/28882300/synchrotron-small-angle-x-ray-scattering-and-electron-microscopy-characterization-of-structures-and-forces-in-microtubule-tau-mixtures
#15
Peter J Chung, Chaeyeon Song, Herbert P Miller, Youli Li, Uri Raviv, Myung Chul Choi, Leslie Wilson, Stuart C Feinstein, Cyrus R Safinya
Tau, a neuronal protein known to bind to microtubules and thereby regulate microtubule dynamic instability, has been shown recently to not only undergo conformational transitions on the microtubule surface as a function of increasing microtubule coverage density (i.e., with increasing molar ratio of Tau to tubulin dimers) but also to mediate higher-order microtubule architectures, mimicking fascicles of microtubules found in the axon initial segment. These discoveries would not have been possible without fine structure characterization of microtubules, with and without applied osmotic pressure through the use of depletants...
2017: Methods in Cell Biology
https://www.readbyqxmd.com/read/28880333/predicting-refractive-surgery-outcome-machine-learning-approach-with-big-data
#16
Asaf Achiron, Zvi Gur, Uri Aviv, Assaf Hilely, Michael Mimouni, Lily Karmona, Lior Rokach, Igor Kaiserman
PURPOSE: To develop a decision forest for prediction of laser refractive surgery outcome. METHODS: Data from consecutive cases of patients who underwent LASIK or photorefractive surgeries during a 12-year period in a single center were assembled into a single dataset. Training of machine-learning classifiers and testing were performed with a statistical classifier algorithm. The decision forest was created by feature vectors extracted from 17,592 cases and 38 clinical parameters for each patient...
September 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28879535/hypercalcemia-a-consultant-s-approach
#17
Ari Auron, Uri S Alon
Due to their daily involvement in mineral metabolism, nephrologists are often asked to consult on children with hypercalcemia. This might become even more pertinent when the hypercalcemia is associated with acute kidney injury and/or hypercalciuria and renal calcifications. The best way to assess the severity of hypercalcemia is by measurement of plasma ionized calcium, and if not available by adjusting serum total calcium to albumin concentration. The differential diagnosis of the possible etiologies of the disturbance in the mineral homeostasis starts with the assessment of serum parathyroid hormone concentration, followed by that of vitamin D metabolites in search of both genetic and acquired etiologies...
September 6, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28877882/mechanotransduction-signaling-in-podocytes-from-fluid-flow-shear-stress
#18
Tarak Srivastava, Hongying Dai, Daniel P Heruth, Uri S Alon, Robert E Garola, Jianping Zhou, R Scott Duncan, Ashraf El-Meanawy, Ellen T McCarthy, Ram Sharma, Mark L Johnson, Virginia J Savin, Mukut Sharma
Recently we and others have found that hyperfiltration-associated increase in biomechanical forces, namely tensile stress and fluid flow shear stress (FFSS) can directly and distinctly alter podocyte structure and function. The ultrafiltrate flow over the major processes and cell body generates FFSS to podocyte. Our previous work suggests that COX2-PGE2-EP2 axis plays an important role in mechanoperception of FFSS in podocyte (Srivastava et al. Am J Physiol Renal Physiol 307: F1323-F1333, 2014). To address mechanotransduction of the perceived mechanical stimulus through EP2 receptor, cultured podocytes were exposed to FFSS (2 dynes/cm2) for 2hrs...
September 6, 2017: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/28866958/perinatal-outcome-of-pregnancies-complicates-with-extreme-birth-weights-at-term
#19
Uri Chavkin, Tamar Wainstock, Eyal Sheiner, Ruslan Sergienko, Asnat Walfisch
OBJECTIVE: To investigate whether an abnormal birthweight at term, either small for gestational age (SGA, < 5(th) centile for gestational age), or large for gestational age (LGA, > 95(th) centile for gestational age), is a risk factor for perinatal complications as compared with birthweight appropriate for gestational age (AGA). METHODS: A population based retrospective cohort analysis of all singleton pregnancies delivered between 1991 and 2014 at Soroka Medical Center...
September 3, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28863456/multiplex-detection-of-pediatric-low-grade-glioma-signature-fusion-transcripts-and-duplications-using-the-nanostring-ncounter-system
#20
Scott Ryall, Anthony Arnoldo, Rahul Krishnatry, Matthew Mistry, Kangzi Khor, Javal Sheth, Cino Ling, Stephie Leung, Michal Zapotocky, Ana Guerreiro Stucklin, Alvaro Lassaletta, Mary Shago, Uri Tabori, Cynthia E Hawkins
Previous studies identified recurrent fusion and duplication events in pediatric low-grade glioma (pLGG). In addition to their role in diagnosis, the presence of these events aid in dictating therapy and predicting patient survival. Clinically, BRAF alterations are most commonly identified using fluorescent in situ hybridization (FISH). However, this method is costly, labor-intensive and does not identify nonBRAF events. Here, we evaluated the NanoString nCounter gene expression system for detecting 32 of the most commonly reported fusion/duplication events in pLGG...
July 1, 2017: Journal of Neuropathology and Experimental Neurology
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