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https://www.readbyqxmd.com/read/29334724/disparity-in-crohn-s-disease-activity-between-home-and-clinics-is-associated-with-unscheduled-hospital-visits-due-to-disease-flares
#1
Eun Soo Kim, Yoo Jin Lee, Byung Ik Jang, Kyeong Ok Kim, Eun Young Kim, Hyun Seok Lee, Seong Woo Jeon, Sang Gyu Kwak
Background/Aims: E-health technologies have been implemented for the management of Crohn's disease (CD). We aimed to identify differences between patient activities at home and at routine clinic visits using a web-based self-reporting CD symptom diary (CDSD) and to determine the impact of this disparity on clinical outcomes. Methods: Patients with CD from three tertiary hospitals were invited to assess their symptoms at least once a week using CDSD. We identified patients who showed disparities in disease activity (high activity at home but normal at the next hospital visit) and evaluated clinical outcomes of these patients such as unscheduled visits due to flares using Kaplan-Meier analyses...
January 17, 2018: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29334475/abandonment-of-assistive-products-assessing-abandonment-levels-and-factors-that-impact-on-it
#2
André T Sugawara, Vinícius D Ramos, Fábio M Alfieri, Linamara R Battistella
PURPOSE: To investigate the levels and factors that influence the abandonment of assistive products by users of a local reference rehabilitation center. METHODS: This observational study involved users who received services and assistive products provided by our center of rehabilitation. Users were identified using the records of the center and their responses about the abandonment were collected through face-to-face interviews. RESULTS: The abandonment level of assistive products was 19...
January 15, 2018: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29334274/an-overview-of-robotic-mechanical-devices-for-post-stroke-thumb-rehabilitation
#3
Marian Suarez-Escobar, Elizabeth Rendon-Velez
PURPOSE: This article aims to clarify the current state-of-the-art of robotic/mechanical devices for post-stroke thumb rehabilitation as well as the anatomical characteristics and motions of the thumb that are crucial for the development of any device that aims to support its motion. METHODS: A systematic literature search was conducted to identify robotic/mechanical devices for post-stroke thumb rehabilitation. Specific electronic databases and well-defined search terms and inclusion/exclusion criteria were used for such purpose...
January 15, 2018: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29334209/comparison-of-the-effects-of-vitrification-on-gene-expression-of-mature-mouse-oocytes-using-cryotop-and-open-pulled-straw
#4
Fardin Amidi, Zahra Khodabandeh, Mohamad Hossain Nori Mogahi
Background: Oocyte cryopreservation is an essential part of the assisted reproductive technology (ART), which was recently introduced into clinical practice. This study aimed to evaluate the effects of two vitrification systems-Cryotop and Open Pulled Straw (OPS)-on mature oocytes gene expressions. MATERIALS AND METHODS: In this experimental study, the survival rate of metaphase II (MII) mouse oocytes were assessed after cryopreservation by vitrification via i. OPS or ii...
April 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29333931/hyperspectral-imaging-of-tissue-perfusion-and-oxygenation-in-wounds-assessing-the-impact-of-a-micro-capillary-dressing
#5
Thomas Wild, Markus Becker, Jochen Winter, Nicole Schuhschenk, Georg Daeschlein, Frank Siemers
OBJECTIVE: Experimental tests of non-invasive multi- or hyperspectral imaging (HSI) systems reveal the high potential of support for medical diagnostic purposes and scientific biomedical analysis. Until now the use of HSI technologies for medical applications was limited by complex and overly sophisticated systems. We present a new and compact HSI-camera that could be used in normal clinical practice. METHOD: We assessed the use of the HSI system on the hands of 10 healthy volunteers, looking at control parameters, and those following venous occlusion, arterial occlusion and reperfusion, including tissue oxygenation, tissue haemoglobin index, perfusion in 4-6mm depth=near infrared spectroscopy (NIR), and tissue water index...
January 2, 2018: Journal of Wound Care
https://www.readbyqxmd.com/read/29333659/acute-renal-replacement-therapy-during-hospitalization-is-training-adequate
#6
Paul M Palevsky
Acute renal replacement therapy is one of the most common interventions provided by nephrologists, however, data on the quality of training provided to nephrology fellows is limited. Extensive curricula for acute renal replacement therapy and the management of poisonings and intoxications have been published, but personal experience suggests that there are significant opportunities to improve training. Particular areas to be considered include the use of novel technologies for assessment of volume status, greater emphasis on the dosing of medications during acute renal replacement therapy, greater training in assessing and tailoring treatment to the goals of care of the individual patient, incorporation of continuous quality improvement tools into the management of acute renal replacement therapy programs and development of robust simulation training to augment training...
January 14, 2018: Seminars in Dialysis
https://www.readbyqxmd.com/read/29333463/characteristics-of-smoothing-filters-to-achieve-the-guideline-recommended-positron-emission-tomography-image-without-harmonization
#7
Yuji Tsutsui, Shinichi Awamoto, Kazuhiko Himuro, Yoshiyuki Umezu, Shingo Baba, Masayuki Sasaki
Objectives: The aim of this study is to examine the effect of different smoothing filters on the image quality and SUVmax to achieve the guideline recommended positron emission tomography (PET) image without harmonization. Methods: We used a Biograph mCT PET scanner. A National Electrical Manufacturers Association (NEMA) the International Electrotechnical Commission (IEC) body phantom was filled with 18F solution with a background activity of 2.65 kBq/mL and a sphere-to-background ratio of 4...
2018: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/29332859/grading-fatty-liver-by-ultrasound-time-domain-radiofrequency-signal-analysis-an-in-vivo-study-of-rats
#8
Wenwu Ling, Jierong Quan, Jiangli Lin, Tingting Qiu, Jiawu Li, Qiang Lu, Changli Lu, Yan Luo
This study aimed to assess the severity of fatty liver (FL) by analyzing ultrasound radiofrequency (RF) signals in rats. One hundred and twenty rats (72 in the FL group and 48 in the control group) were used for this purpose. Histological results were the golden standard: 42 cases had normal livers (N), 30 cases had mild FL (L1), 25 cases had moderate FL (L2), 13 cases presented with severe FL (L3), and 10 cases were excluded from the study. Four RF parameters (Mean, Mean/SD ratio [MSR], skewness [SK], and kurtosis [KU] were extracted...
January 12, 2018: Experimental Animals
https://www.readbyqxmd.com/read/29332824/dithiothreitol-based-protein-equalization-technology-to-unravel-biomarkers-for-bladder-cancer
#9
J E Araújo, H López-Fernández, M S Diniz, Pedro M Baltazar, Luís Campos Pinheiro, Fernando Calais da Silva, Mylène Carrascal, Paula Videira, H M Santos, J L Capelo
This study aimed to assess the benefits of dithiothreitol (DTT)-based sample treatment for protein equalization to assess potential biomarkers for bladder cancer. The proteome of plasma samples of patients with bladder carcinoma, patients with lower urinary tract symptoms (LUTS) and healthy volunteers, was equalized with dithiothreitol (DTT) and compared. The equalized proteomes were interrogated using two-dimensional gel electrophoresis and matrix assisted laser desorption ionization time of flight mass spectrometry...
April 1, 2018: Talanta
https://www.readbyqxmd.com/read/29332786/recent-advances-and-developments-on-integrating-nanotechnology-with-chemiluminescence-assays
#10
REVIEW
Ashish Tiwari, S J Dhoble
Chemiluminescence (CL) techniques are extensively utilized for detection of analytes due to their high sensitivity, rapidity and selectivity. With the advent of nanotechnology and incorporation of the nanoparticles in the CL system has revolutionized the assays due to their unique optical and mechanical properties. Several CL-based reactions have been developed where these nanoparticle based CL sensors have evolved as excellent prospects for sensing in various analytical applications. This review article addresses the nanoparticles based CL detection system that are recently developed, the mechanisms has been summarized and the role of luminophors have been discussed...
April 1, 2018: Talanta
https://www.readbyqxmd.com/read/29332396/an-electrochemical-system-for-the-study-of-trans-plasma-membrane-electron-transport-in-whole-eukaryotic-cells
#11
Harry G Sherman, Carolyn Jovanovic, Snow Stolnik, Frankie James Rawson
The development of new assays to study trans-plasma membrane electron transport (tPMET) in eukaryotic systems is paramount for a number reasons, which include the further understanding of the underlying biology which can then potentially be applied to innovate technological advancements in biosensing, microbial fuel, and pharmaceutical fields. The current literature provides methodology to study these systems that hinges upon mitochondrial knockout genotypes, or the detection of ferrocyanide using colorimetric methods...
January 15, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29332104/assessment-of-the-fit-of-removable-partial-denture-fabricated-by-computer-aided-designing-computer-aided-manufacturing-technology
#12
Khalid A O Arafa
To assess the level of evidence that supports the quality of fit for removable partial denture (RPD) fabricated by computer-aided designing/computer aided manufacturing (CAD/CAM) and rapid prototyping (RP) technology. Methods: An electronic search was performed in Google Scholar, PubMed, and Cochrane library search engines, using Boolean operators. All articles published in English and published in the period from 1950 until April 2017 were eligible to be included in this review. The total number of articles contained the search terms in any part of the article (including titles, abstracts, or article texts) were screened, which resulted in 214 articles...
January 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29331656/effect-of-a-wearable-patient-sensor-on-care-delivery-for-preventing-pressure-injuries-in-acutely-ill-adults-a-pragmatic-randomized-clinical-trial-ls-hapi-study
#13
David Pickham, Nic Berte, Mike Pihulic, Andre Valdez, Barbara Mayer, Manisha Desai
IMPORTANCE: Though theoretically sound, studies have failed to demonstrate the benefit of routine repositioning of at-risk patients for the prevention of hospital acquired pressure injuries. OBJECTIVE: To assess the clinical effectiveness of a wearable patient sensor to improve care delivery and patient outcomes by increasing the total time with turning compliance and preventing pressure injuries in acutely ill patients. DESIGN: Pragmatic, investigator initiated, open label, single site, randomized clinical trial...
December 30, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29331453/are-privacy-enhancing-technologies-for-genomic-data-ready-for-the-clinic-a-survey-of-medical-experts-of-the-swiss-hiv-cohort-study
#14
Jean-Louis Raisaro, Paul J McLaren, Jacques Fellay, Matthias Cavassini, Catherine Klersy, Jean-Pierre Hubaux
PURPOSE: Protecting patient privacy is a major obstacle for the implementation of genomic-based medicine. Emerging privacy-enhancing technologies can become key enablers for managing sensitive genetic data. We studied physicians' attitude toward this kind of technology in order to derive insights that might foster their future adoption for clinical care. METHODS: We conducted a questionnaire-based survey among 55 physicians of the Swiss HIV Cohort Study who tested the first implementation of a privacy-preserving model for delivering genomic test results...
January 10, 2018: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/29331424/ultra-narrow-surface-lattice-resonances-in-plasmonic-metamaterial-arrays-for-biosensing-applications
#15
Artem Danilov, Gleb Tselikov, Fan Wu, Vasyl G Kravets, Igor Ozerov, Frederic Bedu, Alexander N Grigorenko, Andrei V Kabashin
When excited over a periodic metamaterial lattice of gold nanoparticles (~ 100nm), localized plasmon resonances (LPR) can be coupled by a diffraction wave propagating along the array plane, which leads to a drastic narrowing of plasmon resonance lineshapes (down to a few nm full-width-at-half-maximum) and the generation of singularities of phase of reflected light. These phenomena look very promising for the improvement of performance of plasmonic biosensors, but conditions of implementation of such diffractively coupled plasmonic resonances, also referred to as plasmonic surface lattice resonances (PSLR), are not always compatible with biosensing arrangement implying the placement of the nanoparticles between a glass substrate and a sample medium (air, water)...
December 9, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29331301/marrow-adipose-tissue-imaging-in-humans
#16
Vibha Singhal, Miriam A Bredella
Bone strength is affected not only by bone mineral density (BMD) and bone microarchitecture but also its microenvironment. Recent studies have focused on the role of marrow adipose tissue (MAT) in the pathogenesis of bone loss. Osteoblasts and adipocytes arise from a common mesenchymal stem cell within bone marrow and many osteoporotic states, including aging, medication use, immobility, over - and undernutrition are associated with increased marrow adiposity. Advancements in imaging technology allow the non-invasive quantification of MAT...
January 10, 2018: Bone
https://www.readbyqxmd.com/read/29331280/-jurisdictions-on-the-reimbursement-of-new-medical-technologies-by-public-health-insurance-a-systematic-review
#17
REVIEW
Patricia Ex, Susanne Felgner, Cornelia Henschke
BACKGROUND: In Germany reimbursement for new medical technologies is often enforced before a social court. It is likely that these judicial decisions also affect the sickness funds' decisions on requests for reimbursement and thus patient access to new technologies in general. OBJECTIVES: The aim of this study was to identify the technologies that have repeatedly generated court actions and whether these actions have been successful. The focus was on differences between sectors, technology groups and indications...
January 10, 2018: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/29330875/performance-of-the-early-access-ampliseq%C3%A2-mitochondrial-panel-with-degraded-dna-samples-using-the-ion-torrent%C3%A2-platform
#18
Ka Tak Wai, Mark Barash, Peter Gunn
The Early Access AmpliSeq™ Mitochondrial Panel amplifies whole mitochondrial genomes for phylogenetic and kinship identifications, using Ion Torrent™ technology. There is currently limited information on its performance with degraded DNA, a common occurrence in forensic samples. This study evaluated the performance of the Panel with DNA samples degraded in vitro, to mimic conditions commonly found in forensic investigations. Purified DNA from five individuals was heat-treated at five time points each (125°C for 0, 30, 60, 120 and 240 minutes; total n = 25)...
January 13, 2018: Electrophoresis
https://www.readbyqxmd.com/read/29330154/novel-wearable-seismocardiography-and-machine-learning-algorithms-can-assess-clinical-status-of-heart-failure-patients
#19
Omer T Inan, Maziyar Baran Pouyan, Abdul Q Javaid, Sean Dowling, Mozziyar Etemadi, Alexis Dorier, J Alex Heller, A Ozan Bicen, Shuvo Roy, Teresa De Marco, Liviu Klein
BACKGROUND: Remote monitoring of patients with heart failure (HF) using wearable devices can allow patient-specific adjustments to treatments and thereby potentially reduce hospitalizations. We aimed to assess HF state using wearable measurements of electrical and mechanical aspects of cardiac function in the context of exercise. METHODS AND RESULTS: Patients with compensated (outpatient) and decompensated (hospitalized) HF were fitted with a wearable ECG and seismocardiogram sensing patch...
January 2018: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29330100/osteoarthritis-year-in-review-2017-updates-on-imaging-advancements
#20
REVIEW
Nima Hafezi-Nejad, Shadpour Demehri, Ali Guermazi, John A Carrino
OBJECTIVE: This narrative review covers original research publications related to imaging advancements in osteoarthritis (OA) published in the English language between 1st April 2016 and 30th April 2017. METHODS: Relevant human studies (excluding pre-clinical and in-vitro studies), were searched and selected from PubMed database using the search terms of "osteoarthritis (OA)" in combination with "radiography", "magnetic resonance imaging (MRI)", "computed tomography (CT)", "ultrasound", "positron emission tomography (PET)," "single-photon emission computed tomography (SPECT)," and "scintigraphy"...
January 9, 2018: Osteoarthritis and Cartilage
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