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vegetables and cancer

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https://www.readbyqxmd.com/read/28338764/fruit-and-vegetable-intake-and-the-risk-of-cardiovascular-disease-total-cancer-and-all-cause-mortality-a-systematic-review-and-dose-response-meta-analysis-of-prospective-studies
#1
Dagfinn Aune, Edward Giovannucci, Paolo Boffetta, Lars T Fadnes, NaNa Keum, Teresa Norat, Darren C Greenwood, Elio Riboli, Lars J Vatten, Serena Tonstad
Background: Questions remain about the strength and shape of the dose-response relationship between fruit and vegetable intake and risk of cardiovascular disease, cancer and mortality, and the effects of specific types of fruit and vegetables. We conducted a systematic review and meta-analysis to clarify these associations. Methods: PubMed and Embase were searched up to 29 September 2016. Prospective studies of fruit and vegetable intake and cardiovascular disease, total cancer and all-cause mortality were included...
February 22, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28335085/modifications-in-dietary-and-alcohol-intakes-between-before-and-after-cancer-diagnosis-results-from-the-prospective-population-based-nutrinet-sant%C3%A3-cohort
#2
Philippine Fassier, Laurent Zelek, Lucie Lécuyer, Patrick Bachmann, Marina Touillaud, Nathalie Druesne-Pecollo, Pilar Galan, Patrice Cohen, Hélène Hoarau, Paule Latino-Martel, Emmanuelle Kesse-Guyot, Julia Baudry, Serge Hercberg, Mélanie Deschasaux, Mathilde Touvier
Post-diagnosis diet and alcohol consumption may be associated with cancer prognosis, recurrence and mortality. Our aim was to investigate food, nutrient and alcohol intake variations between before and after cancer diagnosis and their determinants in a prospective cohort. Subjects (n=696) were incident cancer cases diagnosed in the NutriNet-Santé cohort between 2009 and 2016. Food, nutrient and alcohol intakes were prospectively collected using repeated non-consecutive 24-h dietary records since subjects' inclusion (i...
March 23, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28335038/a-comparative-effectiveness-education-trial-for-lifestyle-health-behavior-change-in-african-americans
#3
Chanita Hughes Halbert, Scarlett Bellamy, Vanessa Briggs, Ernestine Delmoor, Joseph Purnell, Rodney Rogers, Benita Weathers, Jerry C Johnson
Obesity and excess weight are significant clinical and public health issues that disproportionately affect African Americans because of physical inactivity and unhealthy eating. We compared the effects of alternate behavioral interventions on obesity-related health behaviors. We conducted a comparative effectiveness education trial in a community-based sample of 530 adult African Americans. Outcomes variables were physical activity (PA) and fruit and vegetable intake. Outcomes were evaluated at baseline and 1-month following interventions about shared risk factors for cancer and cardiovascular disease (CVD) (integrated, INT) or CVD only (disease-specific)...
March 18, 2017: Health Education Research
https://www.readbyqxmd.com/read/28334909/changes-in-awareness-of-cancer-risk-factors-among-adult-new-zealanders-caanz-2001-to-2015
#4
R Richards, B McNoe, E Iosua, A I Reeder, R Egan, L Marsh, L Robertson, B Maclennan, A Dawson, R Quigg, A-C Petersen
Behaviour change, specifically that which decreases cancer risk, is an essential element of cancer control. Little information is available about how awareness of risk factors may be changing over time. This study describes the awareness of cancer risk behaviours among adult New Zealanders in two cross-sectional studies conducted in 2001 and 2014/5.Telephone interviews were conducted in 2001 (n = 436) and 2014/5 (n = 1064). Participants were asked to recall things they can do to reduce their risk of cancer...
February 27, 2017: Health Education Research
https://www.readbyqxmd.com/read/28333599/a-community-driven-implementation-of-the-body-and-soul-program-in-churches-in-the-twin-cities-minnesota-2011-2014
#5
Erika Ashley Pinsker, Andrew W Enzler, Megan C Hoffman, Kathleen Thiede Call, Sylvia Amos, Alfred Babington-Johnson, Kolawole Stephen Okuyemi
BACKGROUND: African Americans have high disease and death rates due to cancer and cardiovascular disease. Health promotion efforts to improve diet have the potential to reduce these rates. COMMUNITY CONTEXT: Given their importance in the community and the extent of their reach, churches are effective avenues for health promotion efforts targeting African Americans. The objectives of this project were to promote healthy eating among African American church members, engage African American churches in the implementation of Body and Soul (an evidenced-based program that encourages healthy eating), and implement the program in the community with minimal resources...
March 23, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/28330247/production-of-glucosinolates-phenolic-compounds-and-associated-gene-expression-profiles-of-hairy-root-cultures-in-turnip-brassica-rapa-ssp-rapa
#6
Ill-Min Chung, Kaliyaperumal Rekha, Govindasamy Rajakumar, Muthu Thiruvengadam
Turnip (Brassica rapa ssp. rapa) is an important vegetable crop producing glucosinolates (GSLs) and phenolic compounds. The GSLs, phenolic compound contents and transcript levels in hairy root cultures, as well as their antioxidant, antimicrobial and anticancer activity were studied in turnip. Transgenic hairy root lines were confirmed by polymerase chain reaction (PCR) and reverse transcription-PCR. GSLs levels (glucoallysin, glucobrassicanapin, gluconasturtiin, glucobrassicin, 4-methoxyglucobrassicin, neoglucobrassicin and 4-hydroxyglucobrassicin) and their gene expression levels (BrMYB28, BrMYB29, BrMYB34, BrMYB51, BrMYB122, CYP79 and CYP83) significantly increased in hairy roots compared with that in non-transformed roots...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28326001/the-role-of-plant-processing-for-the-cancer-preventive-potential-of-ethiopian-kale-brassica-carinata
#7
Grace Akinyi Odongo, Nina Schlotz, Corinna Herz, Franziska S Hanschen, Susanne Baldermann, Susanne Neugart, Bernhard Trierweiler, Lara Frommherz, Charles M A P Franz, Benard Ngwene, Abraham Wahid Luvonga, Monika Schreiner, Sascha Rohn, Evelyn Lamy
Background: Ethiopian kale (Brassica carinata) is a horticulturally important crop used as leafy vegetable in large parts of East and Southern Africa. The leaves are reported to contain high concentrations of health-promoting secondary plant metabolites. However, scientific knowledge on their health benefits is scarce. Objective: This study aimed to determine the cancer preventive potential of B. carinata using a human liver in vitro model focusing on processing effects on the pattern of secondary plant metabolites and bioactivity...
2017: Food & Nutrition Research
https://www.readbyqxmd.com/read/28325079/dietary-guidelines-for-the-asia-pacific-region
#8
Colin W Binns, Mi Kyung Lee, Masaharu Kagawa, Wah Yun Low, Qiu Liqian, Georgia S Guldan, Tomiko Hokama, Keiko Nanishi, Sreymom Oy, Li Tang, Alfred Zerfas
Nutrition is a major determinant of health throughout all stages of life and together with smoking is the most important risk factor for morbidity and mortality in the Asia Pacific Region. The workshop participants examined Dietary Guidelines and Food Guides that are in use in our region, together with additional materials from the World Health Organization, UNICEF and the World Cancer Research Foundation. The resulting set of guidelines is meant as a reminder of the main issues to be covered in a general public health education program...
March 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28322154/mechanisms-and-drug-targets-for-pancreatic-cancer-chemoprevention
#9
Deepanshi Dhar, Komal Raina, Rajesh Agarwal
Pancreatic cancer management remains a major challenge to society. Poor prognosis results in dismal survival rates and quality of life for pancreatic cancer patients post chemo/radiation therapies. Although progress has been made in drug development for chemotherapeutics targeting pancreatic cancer, accompanying issues of resistance to these drugs renders the treatment futile. Emerging area of cancer chemoprevention is gaining importance with natural/dietary compounds serving as novel agents with strong anticancer properties; these are pleiotropic agents targeting multiple pathways with minimal toxicities in the surrounding normal tissue...
March 20, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28314286/safety-and-tolerance-of-d-l-methadone-in-combination-with-chemotherapy-in-patients-with-glioma
#10
Julia Onken, Claudia Friesen, Peter Vajkoczy, Martin Misch
BACKGROUND/AIM: D,L-Methadone increases sensitivity toward chemotherapy of different tumor cell populations. We evaluated the safety and tolerance of additional use of D,L-methadone in patients with glioma in combination with chemotherapy. PATIENTS AND METHODS: The dosage, duration of therapy and side-effects related to D,L-methadone were recorded in 27 patients. Toxicity was assessed accordingly to the Common Toxicity Criteria (CTC) of the National Cancer Institute...
March 2017: Anticancer Research
https://www.readbyqxmd.com/read/28302225/-advances-in-research-of-antitumor-mechanisms-of-isothiocyanates
#11
Huimin Wang, Ke Xu
Isothiocyanates (ITCs) are naturally occurring small molecules that are generated by the enzymic hydrolysis of glucosinolate in cruciferous vegetables. Numerous studies showed that ITCs inhibit the growth of tumors by the mechanisms including inducing cell cycle arrest, promoting apoptosis and producing reactive oxygen species in vitro and in vivo. Recent studies showed that ITCs also inhibit metastasis of cancer cells, induce endoplasmic reticulum stress and autophagy. This review summarizes the antitumor mechanisms of ITCs...
March 20, 2017: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/28302140/nighttime-eating-and-breast-cancer-among-chinese-women-in-hong-kong
#12
Mengjie Li, Lap Ah Tse, Wing-Cheong Chan, Chi-Hei Kwok, Siu-Lan Leung, Cherry Wu, Wai-Cho Yu, Priscilla Ming-Yi Lee, Koon-Ho Tsang, Sze-Hong Law, Roel Vermeulen, Fangyi Gu, Neil E Caporaso, Ignatius Tak-Sun Yu, Feng Wang, Xiaohong Rose Yang
BACKGROUND: A novel line of research suggests that eating at nighttime may have several metabolic consequences that are highly relevant to breast cancer. We investigated the association between nighttime eating habits after 10 p.m. and breast cancer in Hong Kong women. METHODS: A hospital-based case-control study was conducted during 2012-2015. A total of 922 patients with incident breast cancer (cases) and 913 hospital controls were recruited and interviewed using a standard questionnaire including information on eating behavior during both daytime and nighttime...
March 17, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/28299033/the-association-of-age-and-gender-with-risk-factors-of-noncommunicable-diseases-among-employees-in-west-of-iran
#13
Nahid Khademi, Mehran Babanejad, Atefeh Asadmobini, Hossein Karim
BACKGROUND: The relationships that age and gender share with risk factors (RFs) of noncommunicable diseases (NCDs) were assessed among a large-scale employ in Western Iran. METHODS: In this epidemiologic cross-sectional study, 7129 employees from Kermanshah Province were assessed using a census method in 2012. Data on RFs of NCD were collected using a standard questionnaire. Demographic information, diet, physical activity, tobacco use, and history of hypertension, history of diabetes, cardiovascular diseases, osteoporosis, and cancer were studied...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28294968/nutrients-and-the-pancreas-an-epigenetic-perspective
#14
REVIEW
Andee Weisbeck, Rick J Jansen
Pancreatic cancer is the fourth most common cause of cancer-related deaths with a dismal average five-year survival rate of six percent. Substitutional progress has been made in understanding how pancreatic cancer develops and progresses. Evidence is mounting which demonstrates that diet and nutrition are key factors in carcinogenesis. In particular, diets low in folate and high in fruits, vegetables, red/processed meat, and saturated fat have been identified as pancreatic cancer risk factors with a proposed mechanism involving epigenetic modifications or gene regulation...
March 15, 2017: Nutrients
https://www.readbyqxmd.com/read/28293540/inverse-association-between-dietary-intake-of-selected-carotenoids-and-vitamin-c-and-risk-of-lung-cancer
#15
Martine Shareck, Marie-Claude Rousseau, Anita Koushik, Jack Siemiatycki, Marie-Elise Parent
While diets rich in fruit and vegetables appear to reduce lung cancer risk, the evidence for individual carotenoid and vitamin intakes has been judged too limited to reach firm conclusions. Data from a case-control study of lung cancer (Montreal, QC, Canada, 1996-2002) were used to investigate the role of dietary intakes of β-carotene, α-carotene, β-cryptoxanthin, lutein/zeaxanthin, lycopene, and vitamin C in lung cancer risk. In-person interviews elicited dietary information from 1,105 incident cases and 1,449 population controls...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28293393/cytotoxic-and-apoptotic-effects-of-different-extracts-of-artemisia-biennis-willd-on-k562-and-hl-60-cell-lines
#16
Zahra Tayarani-Najaran, Farideh-Sadat Makki, Nafiseh-Sadat Alamolhodaei, Mahdi Mojarrab, Seyed Ahmad Emami
OBJECTIVES: Artemisia is a genus of herbs and small shrubs forms an important part of natural vegetation in Iran. It has been reported that several Artemisia species possess anti-proliferative effects. Considering the value of this genus in anti-cancer researches we have chosen Artemisia biennis for cytotoxic and mechanistic studies. MATERIALS AND METHODS: In this study we have investigated the cytotoxic and apoptotic effects of petroleum ether, dichloromethane, ethyl acetate, ethanol, and ethanol: water (1:1 v/v) extracts of A...
February 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28292742/fatty-acid-synthesis-intermediates-represent-novel-noninvasive-biomarkers-of-prostate-cancer-chemoprevention-by-phenethyl-isothiocyanate
#17
Krishna B Singh, Shivendra V Singh
Increased de novo synthesis of fatty acids is a distinctive feature of prostate cancer, which continues to be a leading cause of cancer-related deaths among American men. Therefore, inhibition of de novo fatty acid synthesis represents an attractive strategy for chemoprevention of prostate cancer. We have shown previously that dietary feeding of phenethyl isothiocyanate (PEITC), a phytochemical derived from edible cruciferous vegetables such as watercress, inhibits incidence and burden of poorly-differentiated prostate cancer in Transgenic Adenocarcinoma of Mouse Prostate (TRAMP) model...
March 14, 2017: Cancer Prevention Research
https://www.readbyqxmd.com/read/28288429/human-health-risk-assessment-of-ddts-and-hchs-through-dietary-exposure-in-nanjing-china
#18
Qianqian Zhang, Zhonghuan Xia, Minmin Wu, Liping Wang, Hao Yang
In a market based study in Nanjing, a typical southeast city in China, the most common consumed 23 kinds of foods from eleven different categories (vegetable, fruit, fish, pork, livestock meat, chicken, egg, milk, oil, rice and flour) were sampled in November 2015. The concentrations of DDTs and HCHs in foods were analyzed using gas chromatography with mass spectrometer detector. The residual amounts of DDTs and HCHs in foods were 0.95-3.53 ng g(-1) and 0.32-1.96 ng g(-1), respectively. The highest residual of ∑10OCPs was 4...
March 6, 2017: Chemosphere
https://www.readbyqxmd.com/read/28288186/diet-and-biliary-tract-cancer-risk-in-shanghai-china
#19
Shakira M Nelson, Yu-Tang Gao, Leticia M Nogueira, Ming-Chang Shen, Bingsheng Wang, Asif Rashid, Ann W Hsing, Jill Koshiol
Trends in biliary tract cancer incidence rates have increased in Shanghai, China. These trends have coincided with economic and developmental growth, as well as a shift in dietary patterns to a more Westernized diet. To examine the effect of dietary changes on incident disease, we evaluated associations between diet and biliary tract cancers amongst men and women from a population-based case-control study in Shanghai, China. Biliary tract cancer cases were recruited from 42 collaborating hospitals in urban Shanghai, and population-based controls were randomly selected from the Shanghai Household Registry...
2017: PloS One
https://www.readbyqxmd.com/read/28280414/quercetin-induces-apoptosis-and-cell-cycle-arrest-in-triple-negative-breast-cancer-cells-through-modulation-of-foxo3a-activity
#20
Lich Thi Nguyen, Yeon-Hee Lee, Ashish Ranjan Sharma, Jong-Bong Park, Supriya Jagga, Garima Sharma, Sang-Soo Lee, Ju-Suk Nam
Quercetin, a plant-derived flavonoid found in fruits, vegetables and tea, has been known to possess bioactive properties such as anti-oxidant, anti-inflammatory and anti-cancer. In this study, anti-cancer effect of quercetin and its underlying mechanisms in triple-negative breast cancer cells was investigated. MTT assay showed that quercetin reduced breast cancer cell viability in a time and dose dependent manner. For this, quercetin not only increased cell apoptosis but also inhibited cell cycle progression...
March 2017: Korean Journal of Physiology & Pharmacology
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