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https://www.readbyqxmd.com/read/29049045/nutrition-physical-activity-and-lifestyle-factors-in-prostate-cancer-prevention
#1
Eric Ballon-Landa, John Kellogg Parsons
PURPOSE OF REVIEW: To review current evidence for prostate cancer prevention with nutrition, physical activity, and lifestyle interventions and identify future research directions. RECENT FINDINGS: Multiple preclinical and observational studies have observed that diet, exercise, and lifestyle interventions may play a role in mitigating disease progression, mortality, and overall disease burden for high-grade and fatal prostate cancer. Increased vegetable and fruit intakes, decreased red meat and saturated fat intakes, and increased exercise are potentially associated with decreased risk of incident disease and increased progression-free, prostate cancer-specific, and overall survival...
October 18, 2017: Current Opinion in Urology
https://www.readbyqxmd.com/read/29044265/a-comprehensive-review-of-the-health-perspectives-of-resveratrol
#2
REVIEW
Abdur Rauf, Muhammad Imran, Hafiz Ansar Rasul Suleria, Bashir Ahmad, Dennis G Peters, Mohammad S Mubarak
Many natural products present in our diet, including flavonoids, can prevent the progression of cancer and other diseases. Resveratrol, a natural polyphenol present in various fruits and vegetables, plays an important role as a therapeutic and chemopreventive agent used in the treatment of various illnesses. It exhibits effects against different types of cancer through different pathways. It additionally exerts antidiabetic, anti-inflammatory, and anti-oxidant effects in a variety of cell types. Furthermore, the cardiovascular protective capacities of resveratrol are associated with multiple molecular targets and may lead to the development of novel therapeutic strategies for atherosclerosis, ischemia/reperfusion, metabolic syndrome, and heart failure...
October 18, 2017: Food & Function
https://www.readbyqxmd.com/read/29039333/antioxidant-antibacterial-and-antiproliferative-activities-of-pumpkin-cucurbit-peel-and-puree-extracts-an-in-vitro-study
#3
Muhammad Asif, Syed Ali Raza Naqvi, Tauqir A Sherazi, Matloob Ahmad, Ameer Fawad Zahoor, Sohail Anjum Shahzad, Zaib Hussain, Hassan Mahmood, Nasir Mahmood
Natural resources right from the beginning of the human civilization has paved the way to human being to combat different challenges. The big challenge was to safe the human being from diseases and shortage of food. Plants helped the man in both areas very efficiently. No doubt when plants are used as food actually we are also taking lot of compounds of medicinal values in an excellent combination which naturally reduce the risk of diseases. Extraction and purification of several medicinally important compounds also gave the way to develop pharmaceutical industry in addition to its own therapeutic effects against different lethal diseases...
July 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29037495/residuals-of-organophosphate-esters-in-foodstuffs-and-implication-for-human-exposure
#4
Jinjian Ding, Tongqing Deng, Mengmeng Xu, Shen Wang, Fangxing Yang
Foodstuffs may be contaminated by organophosphate esters (OPEs) and become an important source of human exposure since OPEs are ubiquitous in the environment. In the present study, 10 OPEs were analyzed in various food matrices collected from a city in Eastern China including chicken, pork, fishes, vegetables, tofu, eggs, milk and cereals. The concentrations of Σ10OPEs ranged from 1.1 to 9.6 ng g(-1) fresh weight (fw) in the foodstuffs. Cereals had the highest residual level of total OPEs with a mean value of 5...
October 13, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29034071/apigenin-in-cancer-therapy-anti-cancer-effects-and-mechanisms-of-action
#5
REVIEW
Xiaohui Yan, Miao Qi, Pengfei Li, Yihong Zhan, Huanjie Shao
Apigenin is a common dietary flavonoid that is abundantly present in many fruits, vegetables and Chinese medicinal herbs and serves multiple physiological functions, such as strong anti-inflammatory, antioxidant, antibacterial and antiviral activities and blood pressure reduction. Therefore, apigenin has been used as a traditional medicine for centuries. Recently, apigenin has been widely investigated for its anti-cancer activities and low toxicity. Apigenin was reported to suppress various human cancers in vitro and in vivo by multiple biological effects, such as triggering cell apoptosis and autophagy, inducing cell cycle arrest, suppressing cell migration and invasion, and stimulating an immune response...
2017: Cell & Bioscience
https://www.readbyqxmd.com/read/29031211/cyanidin-3-o-glucoside-inhibits-the-uvb-induced-ros-cox-2-pathway-in-hacat-cells
#6
Yong He, Yunfeng Hu, Xinwei Jiang, Tianfeng Chen, Yuetang Ma, Shi Wu, Jianxia Sun, Rui Jiao, Xiaoling Li, Liehua Deng, Weibin Bai
Ultraviolet (UV) radiation from sunlight, especially UVB (290-320nm), is one of the most important environmental factors that destroys the integrity of the skin and causes epidermal cell apoptosis, potentially even leading to skin cancer. UVB irradiation can cause skin damage by stimulating inflammatory and apoptotic pathways. Anthocyanins are flavonoids that are common in many vegetable foods, and have also demonstrated chemopreventive effects. Cyanidin-3-O-glucoside, as a typical anthocyanin, exhibits anti-inflammatory and anti-oxidant effects...
October 4, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29025506/maintenance-of-lifestyle-changes-at-12-month-follow-up-in-a-nutrition-and-physical-activity-trial-for-cancer-survivors
#7
Fiona G Stacey, David R Lubans, Kathy Chapman, Alessandra Bisquera, Erica L James
OBJECTIVES: In this paper, we report maintenance of behavior change in a nutrition and physical activity intervention for cancer survivors at 12-months follow-up. METHODS: The ENRICH (Exercise and Nutrition Routine Improving Cancer Health) program was an 8-week face-to-face program for cancer survivors and caregivers, focused on healthy eating, healthy weight, resistance training, and a walking program. Randomized controlled trial participants completed a survey and 7-days of pedometry at baseline, 8-weeks, and 20-weeks...
November 1, 2017: American Journal of Health Behavior
https://www.readbyqxmd.com/read/29025004/dietary-patterns-and-risk-of-pancreatic-cancer-a-systematic-review
#8
Jiali Zheng, Mark A Guinter, Anwar T Merchant, Michael D Wirth, Jiajia Zhang, Rachael Z Stolzenberg-Solomon, Susan E Steck
Pancreatic cancer has the highest case fatality rate of all major cancers. : A systematic review using PRISMA guidelines was conducted to summarize the associations between dietary patterns and risk of pancreatic cancer. : PubMed and Web of Science databases were searched for case-control and cohort studies published up to June 15, 2016. : Eligible studies included a dietary pattern as exposure and pancreatic cancer incidence or mortality as outcome and reported odds ratios, hazard ratios, or relative risks, along with corresponding 95%CIs...
September 6, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/29023013/anti-proliferation-and-apoptosis-induction-of-aqueous-leaf-extract-of-carica-papaya-l-on-human-breast-cancer-cells-mcf-7
#9
Fatma Zuhrotun Nisa, Mary Astuti, Agnes Murdiati, Sofia Mubarika Haryana
BACKGROUND AND OBJECTIVE: Breast cancer is the most frequently diagnosed cancer in women. Chemotherapy is the main method of breast cancer treatment but there are side effects. Carica papaya leaves is vegetable foods consumed by most people of Indonesia have potential as anticancer. The aim of this study was to investigate anti-proliferative and apoptotic induced effect of aqueous papaya leaves extracts on human breast cancer cell lines MCF-7. MATERIALS AND METHODS: Inhibitory on cell proliferation was measured by MTT assay while apoptosis induction was measured using Annexin V...
2017: Pakistan Journal of Biological Sciences: PJBS
https://www.readbyqxmd.com/read/29020930/the-xrcc-1-dna-repair-gene-modifies-the-environmental-risk-of-stomach-cancer-a-hospital-based-matched-case-control-study
#10
Nuntiput Putthanachote, Supannee Promthet, Cameron Hurst, Krittika Suwanrungruang, Peechanika Chopjitt, Surapon Wiangnon, Sam Li-Sheng Chen, Amy Ming-Fang Yen, Tony Hsiu-Hsi Chen
BACKGROUND: Previous studies have found that polymorphisms of the DNA repair gene X-ray repair cross-complementing group 1(XRCC1) and environmental factors are both associated with an increased risk of stomach cancer, but no study has reported on the potential additive effect of these factors among Thai people. The aim of this study was to investigate whether the risk of stomach cancer from XRCC1 gene polymorphisms was modified by environmental factors in the Thai population. METHODS: Hospital-based matched case-control study data were collected from 101 new stomach cancer cases and 202 controls, which were recruited from2002 to 2006 and were matched for gender and age...
October 11, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29017525/is-vegetarian-diet-associated-with-a-lower-risk-of-breast-cancer-in-taiwanese-women
#11
Yao-Jen Chang, Yi-Cheng Hou, Li-Ju Chen, Jing-Hui Wu, Chao-Chuan Wu, Yun-Jau Chang, Kuo-Piao Chung
BACKGROUND: Studies on the relationship between vegetarian diet and breast cancer in Asian populations are limited. This study aimed to investigate the relationship between vegetarian diet, dietary patterns, and breast cancer in Taiwanese women. METHODS: This case-control study compared the dietary patterns of 233 breast cancer patients and 236 age-matched controls. A questionnaire about vegetarian diets and 28 frequently-consumed food items was administered to these 469 patients in the surgical department of Taipei Tzu Chi Hospital...
October 10, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28990544/associations-of-dietary-carbohydrates-glycaemic-index-and-glycaemic-load-with-risk-of-bladder-cancer-a-case-control-study
#12
Livia S A Augustin, Martina Taborelli, Maurizio Montella, Massimo Libra, Carlo La Vecchia, Alessandra Tavani, Anna Crispo, Maria Grimaldi, Gaetano Facchini, David J A Jenkins, Gerardo Botti, Diego Serraino, Jerry Polesel
Carbohydrate foods with high glycaemic index (GI) and load (GL) may negatively influence cancer risk. We studied the association of dietary carbohydrates, GI, GL, intake of bread and pasta with risk of bladder cancer using data from an Italian case-control study. The study included 578 men and women with histologically confirmed bladder cancer and 608 controls admitted to the same hospitals as cases for acute, non-neoplastic conditions. OR were estimated by logistic regression models after allowance for relevant confounding factors...
October 9, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28990541/associations-of-dietary-patterns-with-bone-mass-muscle-strength-and-balance-in-a-cohort-of-australian-middle-aged-women
#13
Feitong Wu, Karen Wills, Laura L Laslett, Brian Oldenburg, Graeme Jones, Tania Winzenberg
Influences of dietary patterns on musculoskeletal health are poorly understood in middle-aged women. This cross-sectional analysis from a cohort of 347 women (aged 36-57 years) aimed to examine associations between dietary patterns and musculoskeletal health outcomes in middle-aged women. Diet was measured by the Cancer Council of Victoria FFQ. Total body bone mineral content (TB BMC), femoral neck and lumbar spine bone density (dual-energy X-ray absorptiometry), lower limbs muscle strength (LMS) and balance tests (timed up and go test, step test, functional reach test (FRT) and lateral reach test) were also measured...
October 9, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28983918/how-many-cancer-cases-and-deaths-are-potentially-preventable-estimates-for-australia-in-2013
#14
Louise F Wilson, Annika Antonsson, Adele C Green, Susan J Jordan, Bradley J Kendall, Christina M Nagle, Rachel E Neale, Catherine M Olsen, Penelope M Webb, David C Whiteman
Cancer is a leading cause of disease burden in Australia, particularly fatal burden, accounting for an estimated thirty percent of deaths. Many cancers develop because of exposure to lifestyle and environmental factors that are potentially modifiable. We aimed to quantify the proportions and numbers of cancer deaths and cases in Australia in 2013 attributable to 20 modifiable factors in eight broad groupings that are established causes of cancer, namely: tobacco smoke (smoking and second-hand), dietary factors (low intake of fruit, non-starchy vegetables and dietary fibre; and high intake of red and processed meat), overweight/obesity, alcohol, physical inactivity, solar ultraviolet radiation, infections (seven agents), and reproductive factors (lack of breastfeeding, menopausal hormone therapy use, combined oral contraceptive use)...
October 6, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28983782/electronic-cigarettes-their-constituents-and-potential-links-to-asthma
#15
REVIEW
Phillip W Clapp, Ilona Jaspers
PURPOSE OF REVIEW: Vaping is gaining popularity in the USA, particularly among teens and young adults. While e-cigs are commonly represented as safer alternatives to tobacco cigarettes, little is known regarding the health effects of their short- or long-term use, especially in individuals with pre-existing respiratory diseases such as asthma. Flavored e-cig liquids (e-liquids) and e-cig aerosols contain airway irritants and toxicants that have been implicated in the pathogenesis and worsening of lung diseases...
October 5, 2017: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/28980927/antioxidant-activities-anticancer-activity-and-polyphenolics-profile-of-leaf-fruit-and-stem-extracts-of-pistacia-lentiscus-from-tunisia
#16
M Yemmen, A Landolsi, J Ben Hamida, F Mégraud, M Trabelsi Ayadi
Plant derived compounds have played an important role in the development of several clinically useful anticancer drugs. The aim of the present study was 1) to evaluate for the first time the anti-proliferative activity of a polyphenol enriched extract obtained from leaf, fruit and stem of Tunisian variety of Pistacia lentiscus against two cultured cancer cells, and 2) to carry out a phytochemical analysis of vegetable extracts particularly by determining the chemical composition of phenolics (total polyphenols, flavonoids and condensed tannins content in solvents with varying polarities), 3) to  evaluate the antioxidant activity and identify the major compounds by RP-HPLC...
September 30, 2017: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28979170/epigenetic-regulation-of-gene-expression-induced-by-butyrate-in-colorectal-cancer-involvement-of-microrna
#17
REVIEW
Karen S Bishop, Huawen Xu, Gareth Marlow
Colorectal cancer (CRC) is the third most common cause of cancer mortality globally. Development of CRC is closely associated with lifestyle, and diet may modulate risk. A Western-style diet is characterised by a high intake of red meat but low consumption of fruit, vegetables, and whole cereals. Such a diet is associated with CRC risks. It has been demonstrated that butyrate, produced by the fermentation of dietary plant fibre, can alter both genetic and epigenetic expressions. MicroRNAs (miRNAs) are small non-coding RNAs that are commonly present in both normal and tumour cells...
2017: Genetics & Epigenetics
https://www.readbyqxmd.com/read/28969043/isothiocyanates-suppress-the-invasion-and-metastasis-of-tumors-by-targeting-fak-mmp-9-activity
#18
Yun-Jeong Jeong, Hyun-Ji Cho, Fung-Lung Chung, Xiantao Wang, Hyang-Sook Hoe, Kwan-Kyu Park, Cheorl-Ho Kim, Hyeun-Wook Chang, Sang-Rae Lee, Young-Chae Chang
Isothiocyanates, which are present as glucosinolate precursors in cruciferous vegetables, have strong activity against various cancers. Here, we compared the anti-metastatic effects of isothiocyanates (benzyl isothiocyanate (BITC), phenethyl isothiocyanate (PEITC), and sulforaphane (SFN)) by examining how they regulate MMP-9 expression. Isothiocyanates, particularly PEITC, suppressed 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced MMP-9 activity and invasion in various cancer cell lines. By contrast, N-methyl phenethylamine, a PEITC analog without an isothiocyanate functional group, had no effect...
September 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28968965/association-between-single-nucleotide-polymorphisms-in-the-antioxidant-genes-cat-gr-and-sod1-erythrocyte-enzyme-activities-dietary-and-life-style-factors-and-breast-cancer-risk-in-a-danish-prospective-cohort-study
#19
Tine Iskov Kopp, Ulla Vogel, Lars Ove Dragsted, Anne Tjonneland, Gitte Ravn-Haren
Exposure to estrogens and alcohol consumption - the two only well-established risk factors for breast cancer - are capable of causing oxidative stress, which has been linked to progression of breast cancer. Here, five functional polymorphisms in the antioxidant genes SOD1, CAT and GSR were investigated in 703 breast cancer case-control pairs in the Danish, prospective "Diet, Cancer and Health" cohort together with gene-environment interactions between the polymorphisms, enzyme activities and intake of fruits and vegetables, alcohol and smoking in relation to breast cancer risk...
September 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28968558/associations-between-oral-hygiene-habits-diet-tobacco-and-alcohol-and-risk-of-oral-cancer-a-case-control-study-from-india
#20
Bhawna Gupta, Freddie Bray, Narinder Kumar, Newell W Johnson
OBJECTIVE: This study examines the association between the incidence of oral cancer in India and oral hygiene habits, diet, chewing and smoking tobacco, and drinking alcohol. We also assessed the effects of oral hygiene habits with oral cancer risk among chewers versus never chewers. METHODS: A hospital-based case-control study was conducted in Pune, India, based on face-to-face interviews, anthropometry, and intra-oral examinations conducted for 187 oral cancer cases and 240 controls...
September 29, 2017: Cancer Epidemiology
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