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https://www.readbyqxmd.com/read/27913933/fatigue-reduction-diet-in-breast-cancer-survivors-a-pilot-randomized-clinical-trial
#1
Suzanna Maria Zick, Justin Colacino, Maria Cornellier, Tohfa Khabir, Katie Surnow, Zora Djuric
PURPOSE: Fatigue is a prevalent and burdensome effect of breast cancer. Fatigue has been linked to chronic inflammation, and diets high in antioxidant nutrients have been associated with lesser prevalence and severity of fatigue. Studies are needed, however, to test if antioxidant-rich diets could improve fatigue. METHODS: Pilot, randomized, trial conducted between January 2014 and April 2015, to investigate if a 3-month diet rich in fruit, vegetables, whole grains, and omega-3 fatty acid-rich foods, named the fatigue reduction diet (FRD), improved fatigue and sleep compared to an attention control, named the general health curriculum (GHC)...
December 2, 2016: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27909274/-three-mitral-valve-operations-in-a-patient-with-trousseau-syndrome-and-nonbacterial-thrombotic-endocarditis-caused-by-ovarian-cancer
#2
Masahito Saito, Naoki Asano, Kazunori Ota, Kazuho Niimi, Koyu Tanaka, Shigeyoshi Gon, Hiroshi Takano
A 52-year-old woman was admitted to our hospital for acute right hemi-paresis, left homonymous hemianopia, and fever. Magnetic resonance imaging of the brain showed multiple cerebral infarctions and transesophageal echocardiography (TEE) revealed a vegetation on the posterior leaflet of her mitral valve. Mitral valve repair was performed under a diagnosis of infective endocarditis (IE). Further multiple cerebral infarctions occurred on the 11th postoperative day, resulting in left hemiplegia and dysarthria...
December 2016: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/27886704/position-of-the-academy-of-nutrition-and-dietetics-vegetarian-diets
#3
Vesanto Melina, Winston Craig, Susan Levin
It is the position of the Academy of Nutrition and Dietetics that appropriately planned vegetarian, including vegan, diets are healthful, nutritionally adequate, and may provide health benefits for the prevention and treatment of certain diseases. These diets are appropriate for all stages of the life cycle, including pregnancy, lactation, infancy, childhood, adolescence, older adulthood, and for athletes. Plant-based diets are more environmentally sustainable than diets rich in animal products because they use fewer natural resources and are associated with much less environmental damage...
December 2016: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/27880994/isothiocyanates-in-brassica-potential-anti-cancer-agents
#4
Sharma Anubhuti, Sharma Ashok, Yadav Prashant, Singh Dhiraj
Isothiocyanates are naturally occurring small molecules that are formed from glucosinolate precursors of cruciferous vegetables. Many isothiocyanates, both natural and synthetic, display anti-carcinogenic activity because they reduce activation of carcinogens and increase their detoxification. This minireview summarizes the current knowledge on isothiocyanates and focuses on their role as potential anti-cancer agents.
January 9, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27880063/interactions-between-phytochemicals-from-fruits-and-vegetables-effects-on-bioactivities-and-bioavailability
#5
Minh Anh Thu Phan, Janet Paterson, Martin Bucknall, Jayashree Arcot
The combinations of two or more phytochemicals bring about changes in the ultimate biological effects and/or the bioavailability of each component. A number of mixtures of pure bioactive compounds or phytochemical-containing plant extracts provide synergy with regard to antioxidant status, anti-inflammation, anti-cancer and chemoprevention of several oxidative stress and metabolic disorders in vitro. The biological activities of food phytochemicals depend upon their bioaccessibility and bioavailability which can be affected by the presence of other food components including other bioactive constituents...
November 23, 2016: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/27878984/sulforaphane-induced-apoptosis-in-xuanwei-lung-adenocarcinoma-cell-line-xwlc-05
#6
Lan Zhou, Qian Yao, Yan Li, Yun-Chao Huang, Hua Jiang, Chuan-Qiong Wang, Lei Fan
BACKGROUND: Xuanwei district in Yunnan Province has the highest incidence of lung cancer in China, especially among non-smoking women. Cruciferous vegetables can reduce lung cancer risk by prompting a protective mechanism against respiratory tract inflammation caused by air pollution, and are rich in sulforaphane, which can induce changes in gene expression. We investigated the effect of sulforaphane-induced apoptosis in Xuanwei lung adenocarcinoma cell line (XWCL-05) to explore the value of sulforaphane in lung cancer prevention and treatment...
November 23, 2016: Thoracic Cancer
https://www.readbyqxmd.com/read/27877210/in-vivo-antitumor-effect-of-an-hpv-specific-promoter-driving-il-12-expression-in-an-hpv-16-positive-murine-model-of-cervical-cancer
#7
Victor Hugo Bermúdez-Morales, Geny Fierros-Zarate, Celina García-Meléndrez, Juan Manuel Alcocer-Gonzalez, Ausencio Morales-Ortega, Oscar Peralta-Zaragoza, Kirvis Torres-Poveda, Ana Isabel Burguete-García, Eva Hernández-Márquez, Vicente Madrid-Marina
Human papillomavirus (HPV) is a DNA virus that infects epithelial cells and has been implicated in the development of cervical cancer. Few therapeutic strategies have been designed for the treatment of cervical intraepithelial neoplasia, a precursor of cervical cancer. In these early stages, the HPV E2 protein is the most important viral factor involved in viral gene expression and plays crucial roles during the vegetative viral cycle in epithelial cells. Papillomavirus E2 binds specifically to palindromic ACCN6GGT sequences, referred to as the E2 binding sites (E2BS), which are concentrated within the viral long control region, and which are responsible for regulation of the HPV protein's expression...
2016: Journal of Cancer
https://www.readbyqxmd.com/read/27871798/the-association-of-air-pollution-and-greenness-with-mortality-and-life-expectancy-in-spain-a-small-area-study
#8
Carmen de Keijzer, David Agis, Albert Ambrós, Gustavo Arévalo, Jose M Baldasano, Stefano Bande, Jose Barrera-Gómez, Joan Benach, Marta Cirach, Payam Dadvand, Stefania Ghigo, Èrica Martinez-Solanas, Mark Nieuwenhuijsen, Ennio Cadum, Xavier Basagaña
BACKGROUND: Air pollution exposure has been associated with an increase in mortality rates, but few studies have focused on life expectancy, and most studies had restricted spatial coverage. A limited body of evidence is also suggestive for a beneficial association between residential exposure to greenness and mortality, but the evidence for such an association with life expectancy is still very scarce. OBJECTIVE: To investigate the association of exposure to air pollution and greenness with mortality and life expectancy in Spain...
November 18, 2016: Environment International
https://www.readbyqxmd.com/read/27868444/-plant-based-diets-a-review
#9
Zoltán Szabó, Attila Erdélyi, Andrea Gubicskóné Kisbenedek, Tamás Ungár, Éva Lászlóné Polyák, Szilvia Szekeresné Szabó, Réka Erika Kovács, László Bence Raposa, Mária Figler
Plant-based diet is an old-new trend in nutrition. In this review based on a historical context, we wish to introduce this popular nutritional trend. Our aim is to present plant-based diet as a primary measure for prevention. We intend to critically analyse some past stereotypes related to plant-based diet - whose main components include fruits, vegetables, whole grains, legumes, nuts and seeds - according to the literature (e.g. protein, vitamin B12, folic acid, and iron intake) by doing so we wish to create an adequate conceptual basis for its interpretation...
November 2016: Orvosi Hetilap
https://www.readbyqxmd.com/read/27867044/mitochondrial-dysfunction-in-cancer-chemoprevention-by-phytochemicals-from-dietary-and-medicinal-plants
#10
REVIEW
Anuradha Sehrawat, Ruchi Roy, Subrata K Pore, Eun-Ryeong Hahm, Suman K Samanta, Krishna B Singh, Su-Hyeong Kim, Kamayani Singh, Shivendra V Singh
Cancer chemoprevention, a scientific term coined by Dr. Sporn in the late seventies, implies use of natural or synthetic chemicals to block, delay or reverse carcinogenesis. Phytochemicals derived from edible and medicinal plants have been studied rather extensively for cancer chemoprevention using preclinical models in the past few decades. Nevertheless, some of these agents (e.g., isothiocyanates from cruciferous vegetables like broccoli and watercress) have already entered into clinical investigations. Examples of widely studied and highly promising phytochemicals from edible and medicinal plants include cruciferous vegetables constituents (phenethyl isothiocyanate, benzyl isothiocyanate, and sulforaphane), withaferin A (WA) derived from a medicinal plant (Withania somnifera) used heavily in Asia, and an oriental medicine plant component honokiol (HNK)...
November 17, 2016: Seminars in Cancer Biology
https://www.readbyqxmd.com/read/27864777/bioaccumulation-and-cancer-risk-of-polycyclic-aromatic-hydrocarbons-in-leafy-vegetables-grown-in-soils-within-automobile-repair-complex-and-environ-in-uyo-nigeria
#11
Edu Inam, Felicia Ibanga, Joseph Essien
Using gas chromatography-mass spectrometry and an incremental lifetime cancer risks (ILCRs) assessment model, the bioaccumulation and cancer risk of 16 USEPA priority polycyclic aromatic hydrocarbons (PAHs) in leafy vegetables (Vernonia amygdalina and Lasianthera africanum) grown in soils within an automobile repair complex environment in Uyo, Nigeria was studied. The total PAHs concentrations recorded for soils ranged from 0.02 to 1.77 mg/kg. The highest level of 1.77 mg/kg was recorded for soils from the main automobile repair complex (site 1)...
December 0: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/27864535/effect-of-diet-on-mortality-and-cancer-recurrence-among-cancer-survivors-a-systematic-review-and-meta-analysis-of-cohort-studies
#12
Carolina Schwedhelm, Heiner Boeing, Georg Hoffmann, Krasimira Aleksandrova, Lukas Schwingshackl
CONTEXT: Evidence of an association between dietary patterns and individual foods and the risk of overall mortality among cancer survivors has not been reviewed systematically. OBJECTIVE: The aim of this meta-analysis of cohort studies was to investigate the association between food intake and dietary patterns and overall mortality among cancer survivors. DATA SOURCES: The PubMed and Embase databases were searched. STUDY SELECTION: A total of 117 studies enrolling 209 597 cancer survivors were included...
December 2016: Nutrition Reviews
https://www.readbyqxmd.com/read/27860246/prospective-study-of-the-dietary-inflammatory-index-and-risk-of-breast-cancer-in-postmenopausal-women
#13
Nitin Shivappa, Cindy K Blair, Anna E Prizment, David R Jacobs, James R Hébert
SCOPE: Diet in relation to breast cancer etiology has been studied widely, but results have remained inconsistent. Various dietary components including fruits, vegetables, and meat have been implicated through their effects on inflammation. Using data from the Iowa Women's Health Study we examine prospectively the association between the dietary inflammatory index (DII) and breast cancer incidence. METHODS AND RESULTS: DII scores were computed based on baseline dietary intake assessed by a validated 121-item food frequency questionnaire in a cohort of 34,700 women, aged 55-69 years at recruitment in 1986 and followed for incident breast cancer...
November 10, 2016: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/27860207/mediterranean-diet-gene-interactions-a-targeted-metabolomics-study-in-greek-cypriot-women
#14
Maria G Kakkoura, Kleitos Sokratous, Christiana A Demetriou, Maria A Loizidou, Giorgos Loucaides, Eleni Kakouri, Andreas Hadjisavvas, Kyriacos Kyriacou
SCOPE: A high adherence to the Mediterranean diet (MD) was previously associated with a decreased risk of breast cancer (BC) among Greek-Cypriot women. Additionally, particular polymorphisms were shown to modulate this MD-BC association. Herein, we aimed to investigate the effect of polymorphisms-MD interactions on the levels of specific metabolites that could be related to dietary adherence or enzymatic activity, which is itself modulated by polymorphisms. METHODS AND RESULTS: Greek-Cypriot women who were BC controls and had the lowest or the highest MD adherence (vegetables, fruit, legumes, fish) as assessed by principal component analysis (n = 564) were included...
November 18, 2016: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/27852313/regional-and-social-inequalities-in-the-performance-of-pap-test-and-screening-mammography-and-their-correlation-with-lifestyle-brazilian-national-health-survey-2013
#15
Mariza Miranda Theme Filha, Maria do Carmo Leal, Elaine Fernandes Viellas de Oliveira, Ana Paula Esteves-Pereira, Silvana Granado Nogueira da Gama
BACKGROUND: Mass population screening for the early detection of cervical and breast cancer has been shown to be a safe and effective strategy worldwide and has reduced the incidence and mortality rates of these diseases. The aim of this study is to analyse the reach of screening tests for cervical and breast cancer according to sociodemographic variables and to analyse their correlation with a healthy lifestyle. METHODS: We have analysed data collected from 31...
November 17, 2016: International Journal for Equity in Health
https://www.readbyqxmd.com/read/27843913/quercetin-as-an-emerging-anti-melanoma-agent-a-four-focus-area-therapeutic-development-strategy
#16
REVIEW
Zoey Harris, Micah G Donovan, Gisele Morais Branco, Kirsten H Limesand, Randy Burd
Replacing current refractory treatments for melanoma with new prevention and therapeutic approaches is crucial in order to successfully treat this aggressive cancer form. Melanoma develops from neural crest cells, which express tyrosinase - a key enzyme in the pigmentation pathway. The tyrosinase enzyme is highly active in melanoma cells and metabolizes polyphenolic compounds; tyrosinase expression thus makes feasible a target for polyphenol-based therapies. For example, quercetin (3,3',4',5,7-pentahydroxyflavone) is a highly ubiquitous and well-classified dietary polyphenol found in various fruits, vegetables, and other plant products including onions, broccoli, kale, oranges, blueberries, apples, and tea...
2016: Frontiers in Nutrition
https://www.readbyqxmd.com/read/27827912/chemopreventive-agents-and-inhibitors-of-cancer-hallmarks-may-citrus-offer-new-perspectives
#17
REVIEW
Santa Cirmi, Nadia Ferlazzo, Giovanni E Lombardo, Alessandro Maugeri, Gioacchino Calapai, Sebastiano Gangemi, Michele Navarra
Fruits and vegetables have long been recognized as potentially important in the prevention of cancer risk. Thus, scientific interest in nutrition and cancer has grown over time, as shown by increasing number of experimental studies about the relationship between diet and cancer development. This review attempts to provide an insight into the anti-cancer effects of Citrus fruits, with a focus on their bioactive compounds, elucidating the main cellular and molecular mechanisms through which they may protect against cancer...
November 4, 2016: Nutrients
https://www.readbyqxmd.com/read/27826066/plant-polyphenols-as-natural-drugs-for-the-management-of-down-syndrome-and-related-disorders
#18
REVIEW
Rosa Anna Vacca, Daniela Valenti, Salvatore Caccamese, Maria Daglia, Nady Braidy, Seyed Mohammad Nabavi
Polyphenols are secondary metabolites of plants largely found in fruits, vegetables, cereals and beverages, and therefore represent important constituents of the human diet. Increasing studies have demonstrated the potential beneficial effects of polyphenols on human health. Extensive reviews have discussed the protective effects of polyphenols against a series of diseases such as cancer, cardiovascular diseases, diabetes, and neurodegenerative disorders. Limited studies have investigated the potential therapeutic effects of these natural compounds on neurodevelopmental disorders associated with intellectual disability, such as Down syndrome (DS), for which mitochondrial dysfunctions and oxidative stress are hallmarks and contribute to the deleterious symptoms and cognitive decline...
November 5, 2016: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/27823799/residential-greenness-and-risk-of-prostate-cancer-a-case-control-study-in-montreal-canada
#19
Claire Demoury, Benoît Thierry, Hugues Richard, Brittany Sigler, Yan Kestens, Marie-Elise Parent
BACKGROUND: Recent studies suggest that exposure to greenness favors several health outcomes. We assessed whether living in the proximity of greener areas was related to prostate cancer incidence in a population-based case-control study in Montreal, Canada. MATERIALS AND METHODS: Interviews eliciting lifetime addresses were conducted with 1933 prostate cancer cases diagnosed in 2005-2009 and 1994 population controls. Odds ratios (OR) and 95% confidence intervals (CI) estimated the association between residential greenness, both at recruitment (2005-2009) and about ten years prior (1996), defined by the normalized difference vegetation index (NDVI) around the home, and prostate cancer risk...
November 4, 2016: Environment International
https://www.readbyqxmd.com/read/27823732/cancer-chemoprevention-by-dietary-phytochemicals-epidemiological-evidence
#20
REVIEW
Raúl Baena Ruiz, Pedro Salinas Hernández
BACKGROUND: In recent years, natural compounds called "phytochemicals", which are present in fruits, vegetables, and plants, have received special attention due to their potential to interfere with tumour formation and development. Many of these phytochemicals are being used in chemoprevention strategies. However, the scientific evidence regarding the modification of cancer risk continues to be debated. OBJECTIVE: The aim of this paper is to review the current scientific evidence and the most relevant epidemiological studies regarding the consumption or use of phytochemicals and their effects on the incidence of cancer...
December 2016: Maturitas
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