Jingjing Miao, Muping Di, Boyu Chen, Lin Wang, Yanqing Cao, Weiwei Xiao, Kah Hie Wong, Luo Huang, Manyi Zhu, Huageng Huang, Shaomin Huang, Fei Han, Xiaowu Deng, Yanqun Xiang, Xing Lv, Weixiong Xia, Sze Huey Tan, Joseph T S Wee, Xiang Guo, Melvin L K Chua, Chong Zhao
PURPOSE: Current guideline recommends a uniform method of delineation of subclinical disease within the primary clinical target volume (CTVp) for all stages of nasopharyngeal carcinoma (NPC). We performed a prospective observational study to investigate the outcomes with a reduced CTVp and radiation dose for early-stage NPC. METHODS AND MATERIALS: Patients with newly diagnosed, biopsy-proven World Health Organization type II-III and American Joint Committee on Cancer/Union for International Cancer Control sixth edition stage T1-2N0-1 disease were enrolled...
July 15, 2020: International Journal of Radiation Oncology, Biology, Physics