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https://www.readbyqxmd.com/read/29629353/comparison-of-surgical-outcomes-of-intracorporeal-hepaticojejunostomy-in-the-excision-of-choledochal-cysts-using-laparoscopic-versus-robot-techniques
#1
Hongeun Lee, Wooil Kwon, Youngmin Han, Jae Ri Kim, Sun-Whe Kim, Jin-Young Jang
Purpose: Increasing surgical expertise in minimally invasive surgery has allowed laparoscopic surgery to be performed in many abdominal surgeries. Laparoscopic choledochal cyst excision and Roux-en-Y hepaticojejunostomy are challenging and sophisticated surgeries because of the difficult anastomosis. Recent advances in robotic surgery have enabled more delicate and precise movements, and Endowrist instruments allow for securing sutures during anastomosis. This study aimed to compare surgical outcomes of laparoscopic and robotic hepaticojejunostomy in choledochal cyst excision...
April 2018: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/29615085/expression-patterns-of-stat3-erk-and-estrogen-receptor-%C3%AE-are-associated-with-development-and-histologic-severity-of-hepatic-steatosis-a-retrospective-study
#2
Euno Choi, Won Kim, Sae Kyung Joo, Sunyoung Park, Jeong Hwan Park, Yun Kyung Kang, So-Young Jin, Mee Soo Chang
BACKGROUND: Hepatic steatosis renders hepatocytes vulnerable to injury, resulting in the progression of preexisting liver disease. Previous animal and cell culture studies implicated mammalian target of rapamycin (mTOR), signal transducer and activator of transcription-3 (STAT3), extracellular signal-regulated kinase (ERK) and estrogen-receptor α in the pathogenesis of hepatic steatosis and disease progression. However, to date there have been few studies performed using human liver tissue to study hepatic steatosis...
April 3, 2018: Diagnostic Pathology
https://www.readbyqxmd.com/read/29594465/interpreting-body-mri-cases-classic-findings-in-abdominal-mri
#3
REVIEW
Leann Kania, Flavius Guglielmo, Donald Mitchell
Few things in radiology are "pathognomonic" in their appearance or presentation. However, having an awareness of those findings which are specific to a certain entity is important when interpreting imaging studies. These classic findings can be identified with many imaging modalities, but no modality provides as many recognizable observations as an MRI. This results from the large variety of pulse sequences that provide high contrast resolution, prior to and following contrast administration. In this article, the most classically recognized abdominal findings are presented including the following: Liver: Cyst, hemangioma, focal nodular hyperplasia, hepatic adenoma, hemosiderosis, hepatocellular carcinoma...
March 28, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29574408/european-evidence-based-guidelines-on-pancreatic-cystic-neoplasms
#4
(no author information available yet)
Evidence-based guidelines on the management of pancreatic cystic neoplasms (PCN) are lacking. This guideline is a joint initiative of the European Study Group on Cystic Tumours of the Pancreas, United European Gastroenterology, European Pancreatic Club, European-African Hepato-Pancreato-Biliary Association, European Digestive Surgery, and the European Society of Gastrointestinal Endoscopy. It replaces the 2013 European consensus statement guidelines on PCN. European and non-European experts performed systematic reviews and used GRADE methodology to answer relevant clinical questions on nine topics (biomarkers, radiology, endoscopy, intraductal papillary mucinous neoplasm (IPMN), mucinous cystic neoplasm (MCN), serous cystic neoplasm, rare cysts, (neo)adjuvant treatment, and pathology)...
March 24, 2018: Gut
https://www.readbyqxmd.com/read/29543508/primary-cilia-disruption-differentially-affects-the-infiltrating-and-resident-macrophage-compartment-in-the-liver
#5
Kurt A Zimmerman, Cheng Jack Song, Nancy Gonzalez-Mize, Zhang Li, Bradley K Yoder
Hepatorenal fibrocystic disease (HRFCD) is characterized by cysts in the kidney and liver with associated fibrosis and is the result of defects in proteins required for cilia function or assembly. Previous reports indicate that macrophages, mainly M2-like macrophages, contribute to HRFCD, although the origin (yolk-sac derived resident macrophages vs bone-marrow derived infiltrating macrophages) and contribution of these cells to the observed phenotypes is unknown. Herein, we utilize a congenital model of cilia dysfunction (IFT88Orpk ) to study the importance of macrophages in HRFCD...
March 15, 2018: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/29512796/adult-s-congenital-bile-duct-cysts
#6
Omar Toumi, Mohamed Ali Chaouch, Abdesslem Ghedira, Ibtissem Korbi, Mohamed Nasr, Faouzi Noomene, Khadija Zouari, Randa Salem, Badii Hamida, Mondher Golli
INTRODUCTION: Congenital bile duct cysts (CBDC) is a rare congenital malformation. It results from an anomaly of the biliopancreatic junction (AJBP). This condition is often diagnosed at a young age. Although, it can be asymptomatic and discovered only at an advanced age. The aim of our work was to describe the diagnosis, therapeutic and evolutionary aspects of BVCD through a series of 11 cases diagnosed in adult cases. METHODS: This is a descriptive, retrospective and monocentric study...
June 2017: La Tunisie Médicale
https://www.readbyqxmd.com/read/29504349/choledochal-cyst-and-biliary-stone
#7
Anjum Saeed, Asaad Assiri
Choledochal cyst is not an uncommonly seen entity in children. Presentation may be varied and at different age groups. Abnormal pancreaticobiliary junction is usually a phenomenon in acquired type of choledochal cyst. A four years old child presented with symptoms of acute viral hepatitis A but persistence of symptoms beyond the usual time necessitated other conditions to be considered. Choledochal cyst was the final diagnosis complicating with biliary stone which was managed by surgical excision.
January 2018: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29485804/what-is-the-right-therapeutic-approach-to-biliary-choledochal-cyst
#8
Marinko Marušić, Anto Dominković, Željka Belošić Halle, Rosana Troskot Perić, Ivan Zoričić, Darko Vukušić, Ana Marija Liberati Čizmek
We report a case of biliary cyst type II which, independently of its a priori benign nature, caused numerous complications such as recurrent cholangitis and pancreatitis, as well as subsequent hepatic fibrosis and the potential danger of choledochocele perforation. Although they are benign, biliary/choledochal cysts can cause numerous disorders such as cholestasis, leading to cholangitis and pancreatitis and biliary sepsis, and due to chronic inflammation of the biliary system even cholangiocarcinogenesis. Our findings showed that sometimes this type of biliary cyst (according to the available literature the rarest and most benign type), as well as type I cyst, should undergo timely radical excision...
June 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29480528/meta-analysis-of-risk-of-developing-malignancy-in-congenital-choledochal-malformation
#9
REVIEW
A Ten Hove, V E de Meijer, J B F Hulscher, R H J de Kleine
BACKGROUND: Choledochal malformations comprise various congenital cystic dilatations of the extrahepatic and/or intrahepatic biliary tree. Choledochal malformation is generally considered a premalignant condition, but reliable data on the risk of malignancy and optimal surgical treatment are lacking. The objective of this systematic review was to assess the prevalence of malignancy in patients with choledochal malformation and to differentiate between subtypes. In addition, the risk of malignancy following cystic drainage versus complete cyst excision was assessed...
February 26, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29479444/comparative-analysis-of-different-hepatico-jejunostomy-techniques-for-treating-adult-type-i-choledochal-cyst
#10
Wenjie Ma, Yongqiong Tan, Anuj Shrestha, Fuyu Li, Rongxing Zhou, Junke Wang, Haijie Hu, Qin Yang
Objective: To compare Roux-en-Y hepatico-jejunostomy with complete resection of the cyst or incomplete resection with 1-cm remnant proximal cyst wall in treating adult type I choledochal cyst (CC). Methods: The medical records of 267 adult patients with type I CC from January 1998 to December 2015 were reviewed retrospectively. Among them, 171 underwent Roux-en-Y hepatico-jejunostomy with complete resection (PBD 0-cm group) and 96 underwent Roux-en-Y hepatico-jejunostomy with 1-cm proximal cyst wall left (PBD 1-cm group)...
February 2018: Gastroenterology Report
https://www.readbyqxmd.com/read/29465585/occurrence-of-signet-ring-cell-carcinoma-with-cholangiocarcinoma-25-years-after-choledochal-cyst-excision-a-case-report
#11
Conggui Zhang, Jianpeng Zhou, Kai Kou, Shouling Liu, Feng We, Guangyi Wang
RATIONALE: Choledochal cysts are a risk factor for the development of cholangiocarcinoma. Hence, complete surgical excision is the preferred treatment in most cases. However, cholangiocarcinoma still can develop from the remnant biliary system after surgical excision. Signet-ring cell carcinoma is a rare type of cancer of the biliary system, and the occurrence of signet-ring cell carcinoma after surgical excision of choledochal cysts has not been reported in the English literature to date...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29372374/cysto-cholecystostomy-a-more-physiological-procedure-for-hepatic-cysts-with-biliary-communications-and-cystic-dilatations-of-main-intrahepatic-ducts
#12
Mei Diao, Long Li, Wei Cheng
OBJECTIVE: Hepatic cysts with biliary communications (HC) and cystic dilatations of main intrahepatic ducts (CIHD) can cause biliary obstruction, cholestasis, stone formation, cholangitis, liver damage and carcinoma. Conventionally, Roux-Y cysto-jejunostomy is employed to manage these conditions. However, it is technically demanding and may be complicated with major biliary disruption and bacteria migration from intestine to intrahepatic duct. We have carried out laparoscopic cysto-cholecystostomies for HC with biliary communication and CIHD and evaluated outcomes...
January 25, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29343773/mitochondrial-mutations-in-cholestatic-liver-disease-with-biliary-atresia
#13
Hong Koh, Gun-Seok Park, Sun-Mi Shin, Chang Eon Park, Seung Kim, Seok Joo Han, Huy Quang Pham, Jae-Ho Shin, Dong-Woo Lee
Biliary atresia (BA) results in severe bile blockage and is caused by the absence of extrahepatic ducts. Even after successful hepatic portoenterostomy, a considerable number of patients are likely to show progressive deterioration in liver function. Recent studies show that mutations in protein-coding mitochondrial DNA (mtDNA) genes and/or mitochondrial genes in nuclear DNA (nDNA) are associated with hepatocellular dysfunction. This observation led us to investigate whether hepatic dysfunctions in BA is genetically associated with mtDNA mutations...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29323060/spectrum-of-hepatobiliary-cystic-lesions-a-7-year-experience-at-a-tertiary-care-referral-center-in-north-india-and-review-of-literature
#14
Prasenjit Das, Pragya Sharma, Tripti Nakra, Shouriyo Ghosh, Rajni Yadav, Brijnandan Gupta, Gaurav Khanna, K S Madhusudhan, Rajesh Panwar, M K Anoop, Ragini Kilambi, Anand N Singh, Nihar R Dash, Sujoy Pal, Siddhartha Datta Gupta
CONTEXT: Cysts arising from the hepatobiliary tree are a group of heterogeneous lesions with regard to pathogenesis, clinical presentation, and radiological finding. They can be intrahepatic or extrahepatic, developmental, secondary to infective/inflammatory etiologies, as well as neoplastic. This study was conducted to determine the spectrum of hepatobiliary cysts in surgically intervened cases, with regard to their prevalence, histological spectrum, and clinicoradiological correlation, wherever possible...
October 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/29322850/clinical-significance-of-intrapancreatic-choledochal-cyst-excision-in-surgical-management-of-type-i-choledochal-cyst
#15
Fei Fan, Da-Peng Xu, Zheng-Xiang Xiong, Hai-Jia Li, Hai-Bei Xin, Huan Zhao, Jin-Wei Zhang
Objective To investigate the effectiveness of intrapancreatic choledochal cyst excision in treating type I choledochal cyst, and increase understanding of the need for thorough surgical management of the disease. Methods Primary and secondary (including multiple) surgical cases, treated between 2005 and 2015, were retrospectively analysed, and follow-up data of post-treatment effectiveness to date were reviewed. Differences in curative effects were compared between whole and partial excision of the choledochal cyst...
March 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29319199/histopathological-frequency-of-feline-hepatobiliary-disease-in-the-uk
#16
W A Bayton, C Westgarth, T Scase, D J Price, N H Bexfield
OBJECTIVES: To determine the histopathological frequency of feline hepatobiliary diseases in the UK and to identify breed, age and gender predispositions to developing individual diseases. METHODS: Histopathology results from 1452 feline liver biopsies were assessed. A control population of microchipped cats was used for breed comparison. Data were retrospectively categorised into hepatobiliary diseases according to World Small Animal Veterinary Association standards...
January 10, 2018: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/29312974/robotic-assisted-excision-of-type-i-choledochal-cyst-with-roux-en-y-hepaticojejunostomy-reconstruction
#17
EDITORIAL
Shin-E Wang, Shih-Chin Chen, Bor-Uei Shyr, Yi-Ming Shyr
Choledochal cyst is a relatively rare congenital disease. The current standard treatment of choice for choledochal cyst is complete excision with Roux-en-y hepaticojejunostomy due to possible associated complications if left untreated, such as cholangitis, pancreatitis, cirrhosis, portal hypertension, and biliary malignancy. Traditionally, the resection for choledochal cyst is carried out with open surgery because of complex dissection and bilioenteric reconstruction. Recently, minimal invasive approach has gain wide interest, especially with the use of robotic surgical systems which can facilitate complex minimal access procedures...
December 2017: Hepatobiliary Surgery and Nutrition
https://www.readbyqxmd.com/read/29311401/hepatic-cyst-compressing-the-right-atrial-and-ventricular-inflow-tract-an-uncommon-cardiac-complication
#18
Maulik Panchal, Ahmed Alansari, Marc Wallack, Ferdinand Visco, Susan Williams, Alexander M Sy
Commonly reported complications of hepatic cysts are spontaneous hemorrhage, rupture into the peritoneal cavity, infection and compression of the biliary tree however cardiac complications are not commonly reported. We are presenting a case of a large liver cyst presenting with right atrial and ventricular inflow tract impingement resulting in cardiac symptoms. A 68 year-old Hispanic female presented with one month of fatigue and shortness of breath after household work and walking less than one block, right upper quadrant pain and weight loss...
January 2018: Annals of Hepatology
https://www.readbyqxmd.com/read/29251269/ii-brazilian-consensus-statement-on-endoscopic-ultrasonography
#19
Fauze Maluf-Filho, Joel Fernandez de Oliveira, Ernesto Quaresma Mendonça, Augusto Carbonari, Bruno Antônio Maciente, Bruno Chaves Salomão, Bruno Frederico Medrado, Carlos Marcelo Dotti, César Vivian Lopes, Cláudia Utsch Braga, Daniel Alencar M Dutra, Felipe Retes, Frank Nakao, Giovana Biasia de Sousa, Gustavo Andrade de Paulo, Jose Celso Ardengh, Juliana Bonfim Dos Santos, Luciana Moura Sampaio, Luciano Okawa, Lucio Rossini, Manoel Carlos de Brito Cardoso, Marco Antonio Ribeiro Camunha, Marcos Clarêncio, Marcos Eduardo Lera Dos Santos, Matheus Franco, Nutianne Camargo Schneider, Ramiro Mascarenhas, Rodrigo Roda, Sérgio Matuguma, Simone Guaraldi, Viviane Figueiredo
BACKGROUND AND OBJECTIVES: At the time of its introduction in the early 80s, endoscopic ultrasonography (EUS) was indicated for diagnostic purposes. Recently, EUS has been employed to assist or to be the main platform of complex therapeutic interventions. METHODS: From a series of relevant new topics in the literature and based on the need to complement the I Brazilian consensus on EUS, twenty experienced endosonographers identified and reviewed the pertinent literature in databases...
November 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/29234186/primary-leiomyosarcoma-of-the-mesentery-a-case-report
#20
Varsha Dalal, Manveen Kaur, Reetika Menia, Fouzia Siraj, Amar Bhatnagar, Usha Agrawal
Mesenteric masses are infrequent lesions ranging from benign cysts to aggressive malignancies and often present a diagnostic and therapeutic challenge. The mesentery is a frequent recipient of metastases from the gastrointestinal tract, pancreas, and biliary cancers. Primary mesenteric tumors are relatively rare, mostly mesenchymal in origin and benign in nature. Examples include gastrointestinal stromal tumors and smooth muscle tumors. We describe a 50-year-old woman, who presented with a lump in the left hypochondrium along with altered bowel habits of 2 years' duration...
September 2017: Iranian Journal of Medical Sciences
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