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https://www.readbyqxmd.com/read/28430086/genotypic-relatedness-and-antimicrobial-resistance-of-salmonella-heidelberg-isolated-from-chickens-and-turkeys-in-the-midwestern-united-states
#1
Muhammad Nisar, Issmat I Kassem, Gireesh Rajashekara, Sagar M Goyal, Dale Lauer, Shauna Voss, Kakambi V Nagaraja
Salmonella is one of the most common causes of foodborne illnesses in humans in the United States, and domestic poultry is considered an important source of this pathogen. Salmonella enterica subsp. enterica serovar Heidelberg is the fourth most commonly reported Salmonella from retail meats and food animals in the United States. We assessed the genotypes and antimicrobial resistance phenotypes of Salmonella Heidelberg isolated from various chicken and turkey hatcheries and breeder farms in the Midwest. The genotypes of 33 S...
May 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28429448/white-matter-microstructure-variations-contribute-to-neurological-soft-signs-in-healthy-adults
#2
Dusan Hirjak, Philipp A Thomann, Robert C Wolf, Katharina M Kubera, Caspar Goch, Jan Hering, Klaus H Maier-Hein
OBJECTIVE: Neurological soft signs (NSS) are core features of psychiatric disorders with significant neurodevelopmental origin. However, it is unclear whether NSS correlates are associated with neuropathological processes underlying the disease or if they are confounded by medication. Given that NSS are also present in healthy persons (HP), investigating HP could reveal NSS correlates, which are not biased by disease-specific processes or drug treatment. Therefore, we used a combination of diffusion MRI analysis tools to provide a framework of specific white matter (WM) microstructure variations underlying NSS in HP...
April 21, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28427889/lost-in-translation-cultural-divides-in-communication-skills-teaching-identified-in-the-icch-2016-student-symposium
#3
Heather K Schopper, Nasteha A Mohamed, Max Seegel, Kseniya Gorina, Jonathan Silverman, Marcy Rosenbaum
OBJECTIVE: To provide a platform for learners' voices at an international conference on communication in healthcare. METHODS: A group of medical students were invited to explore their experiences with communication skills learning at a symposium at the 2016 International Conference on Communication in Healthcare in Heidelberg, DE. RESULTS: Students from the US, Denmark, Germany, and Russia discussed their experiences with communication skills curriculum at their institutions...
April 12, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28426001/remote-epitaxy-through-graphene-enables-two-dimensional-material-based-layer-transfer
#4
Yunjo Kim, Samuel S Cruz, Kyusang Lee, Babatunde O Alawode, Chanyeol Choi, Yi Song, Jared M Johnson, Christopher Heidelberger, Wei Kong, Shinhyun Choi, Kuan Qiao, Ibraheem Almansouri, Eugene A Fitzgerald, Jing Kong, Alexie M Kolpak, Jinwoo Hwang, Jeehwan Kim
Epitaxy-the growth of a crystalline material on a substrate-is crucial for the semiconductor industry, but is often limited by the need for lattice matching between the two material systems. This strict requirement is relaxed for van der Waals epitaxy, in which epitaxy on layered or two-dimensional (2D) materials is mediated by weak van der Waals interactions, and which also allows facile layer release from 2D surfaces. It has been thought that 2D materials are the only seed layers for van der Waals epitaxy...
April 19, 2017: Nature
https://www.readbyqxmd.com/read/28422029/interpreting-treatment-related-changes-using-the-tinnitus-questionnaire-in-argstatter-h-grapp-m-plinkert-pk-bolay-hv-heidelberg-neuro-music-therapy-for-chronic-tonal-tinnitus-treatment-outline-and-psychometric-evaluation-int-tinnitus-j-2012-17-1-31-41
#5
https://www.readbyqxmd.com/read/28419397/influence-of-retinal-pathology-on-the-reliability-of-macular-thickness-measurement-a-comparison-between-optical-coherence-tomography-devices
#6
Bobak Bahrami, Shaun Y P Ewe, Thomas Hong, Meidong Zhu, Germane Ong, Kehui Luo, Andrew Chang
BACKGROUND AND OBJECTIVE: To evaluate the repeatability, reliability, and comparability of macular thickness measurements between three optical coherence tomography (OCT) machines in healthy eyes, eyes with diabetic macular edema (DME), and eyes with neovascular age-related macular degeneration (nAMD). PATIENTS AND METHODS: Twenty-three eyes with DME, 26 eyes with nAMD, and 24 healthy eyes as controls were evaluated. Scans were performed using the swept-source Triton (Topcon, Tokyo, Japan), the spectral-domain Cirrus (Carl Zeiss Meditec, Dublin, CA), and the Spectralis (Heidelberg Engineering, Heidelberg, Germany) machines...
April 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28413889/shedding-light-into-the-black-box-a-prospective-longitudinal-study-identifying-the-canmeds-roles-of-final-year-medical-students-on-ward-activities
#7
Till Johannes Bugaj, Carolin Schmid, Ansgar Koechel, Jan Stiepak, Jan B Groener, Wolfgang Herzog, Christoph Nikendei
INTRODUCTION: To our best knowledge, a rigorous prospective analysis of final year medical students' (FY medical students) activity profiles during workplace learning is lacking. The present study investigated the CanMEDS characteristics of all on-ward activities performed by internal medicine FY medical students. We tested the hypotheses that during FY medical student workplace training (I) routine activities are predominantly performed, while supervised, more complex activities are underrepresented with (II) FY medical students performing an insufficient number of autonomous activities and that (III) the CanMEDS roles of the Communicator and the Professional prevail...
April 15, 2017: Medical Teacher
https://www.readbyqxmd.com/read/28410453/effects-of-acupuncture-on-gait-of-patients-with-multiple-sclerosis
#8
Maria Begoña Criado, Maria João Santos, Jorge Machado, Arminda Manuela Gonçalves, Henry Johannes Greten
Multiple sclerosis is considered a complex and heterogeneous disease. Approximately 85% of patients with multiple sclerosis indicate impaired gait as one of the major limitations in their daily life. Acupuncture studies found a reduction of spasticity and improvement of fatigue and imbalance in patients with multiple sclerosis, but there is a lack of studies regarding gait. We designed a study of acupuncture treatment, according to the Heidelberg model of Traditional Chinese Medicine (TCM), to investigate if acupuncture can be a useful therapeutic strategy in patients with gait impairment in multiple sclerosis of relapsing-remitting type...
April 14, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28406796/experimental-dosimetric-comparison-of-1-h-4-he-12-c-and-16-o-scanned-ion-beams
#9
T Tessonnier, A Mairani, S Brons, T Haberer, J Debus, K Parodi
At the Heidelberg Ion Beam Therapy Center, scanned helium and oxygen ion beams are available in addition to the clinically used protons and carbon ions for physical and biological experiments. In this work, a study of the basic dosimetric features of the different ions is performed in the entire therapeutic energy range. Depth dose distributions are investigated for pencil-like beam irradiation, with and without a modulating ripple filter, focusing on the extraction of key Bragg curve parameters, such as the range, the peak-width and the distal 80%-20% fall-off...
April 13, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28404668/nasalised-distribution-of-peripapillary-retinal-nerve-fibre-layers-in-large-discs
#10
Eun Jung Lee, Jong Chul Han, Changwon Kee
BACKGROUND: To describe the distribution pattern of the peripapillary retinal nerve fibre layer (RNFL) and major retinal vessel positions in patients with a large disc. METHODS: The medical records of patients with a large disc and those of normal controls were reviewed retrospectively. Comprehensive ophthalmic examinations including Cirrus HD-optical coherence tomography (OCT) and Heidelberg Retinal Tomography III (HRT III) were performed. We divided patients into two groups (large disc group and control group) using an HRT-measured disc size of 2...
April 12, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28402393/metcirc-navigating-mass-spectral-similarity-in-high-resolution-ms-ms-metabolomics-data
#11
Thomas Naake, Emmanuel Gaquerel
Summary: Among the main challenges in metabolomics are the rapid dereplication of previously characterized metabolites across a range of biological samples and the structural prediction of unknowns from MS/MS data. Here, we developed MetCirc to comprehensively align and calculate pairwise similarity scores among MS/MS spectral data and visualize these across a range of biological samples. MetCirc comprises functionalities to interactively organize these data according to compound familial groupings and to accelerate the discovery of shared metabolites and hypothesis formulation for unknowns...
April 11, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28400890/comparison-of-ethnic-specific-databases-in-heidelberg-retina-tomography-3-to-discriminate-between-early-glaucoma-and-normal-chinese-eyes
#12
Xiu Ling Tan, Sae Cheong Yap, Xiang Li, Leonard W Yip
PURPOSE: To compare the diagnostic accuracy of the 3 race-specific normative databases in Heidelberg Retina Tomography (HRT)-3, in differentiating between early glaucomatous and healthy normal Chinese eyes. METHOD: 52 healthy volunteers and 25 glaucoma patients were recruited for this prospective cross-sectional study. All underwent standardized interviews, ophthalmic examination, perimetry and HRT optic disc imaging. Area under the curve (AUC) receiver operating characteristics, sensitivity and specificity were derived to assess the discriminating abilities of the 3 normative databases, for both Moorfields Regression Analysis (MRA) and Glaucoma Probability Score (GPS)...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28396974/sarcopenic-overweight-is-associated-with-early-acute-limiting-toxicity-of-anti-pd1-checkpoint-inhibitors-in-melanoma-patients
#13
Heidelberger Valentine, Goldwasser François, Kramkimel Nora, Jouinot Anne, Huillard Olivier, Boudou-Rouquette Pascaline, Chanal Johan, Arrondeau Jennifer, Franck Nathalie, Alexandre Jérôme, Blanchet Benoît, Leroy Karen, Avril Marie-Françoise, Dupin Nicolas, Aractingi Sélim
Little is known on factors predicting toxicity of anti-PD1 checkpoint inhibitors. Sarcopenic obesity is associated with increased acute toxicity of cytotoxic agents and targeted therapies. We explored whether body composition also influenced the occurrence of early acute limiting toxicity (ALT) of anti-PD1 in melanoma patients. This is a monocentric, retrospective study analyzing toxicity outcome in consecutive melanoma patients treated with nivolumab or pembrolizumab. Various parameters linked to the patient or the disease status have been analysed...
April 10, 2017: Investigational New Drugs
https://www.readbyqxmd.com/read/28389700/the-predictability-of-ocriplasmin-treatment-effects-is-there-consensus-among-retinal-experts-results-from-the-export-study
#14
Thomas Bertelmann, Joachim Wachtlin, Stefan Mennel, Michael J Koss, Mathias M Maier, Ricarda G Schumann, Sara Kazerounian, Hanna Daniel, Steffen Schmitz-Valckenberg
PURPOSE: To evaluate the agreement and predictability of ocriplasmin treatment effects among retinal experts (raters) by assessment of retinal imaging data of eyes treated for vitreomacular traction in nine different centers in Germany and Austria. METHODS: Retrospective cohort study. Combined confocal near-infrared scanning laser ophthalmoscopy and spectral-domain optical coherence tomography images (Spectralis® device, Heidelberg Engineering GmbH, Germany) from 136 eyes of 135 subjects were reviewed by 14 raters using an internet-based grading database and a standardized questionnaire...
April 7, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28379524/evaluation-of-usda-approved-antimicrobials-on-the-reduction-of-salmonella-and-campylobacter-in-ground-chicken-frames-and-their-effect-on-meat-quality
#15
A Moore, R Nannapaneni, A Kiess, C S Sharma
The main objective of this study was to examine the efficacy of USDA approved antimicrobials in reducing Salmonella Heidelberg (S. H.) and Campylobacter jejuni (C. j.) in ground chicken frames and to determine the treatment effects on total aerobic counts and meat color. Six antimicrobials (0.1% peracetic acid [PAA], 0.6% cetylpyridinium chloride [CPC], 0.005% sodium hypochlorite, 1.5% acidified lactic acid [ALA], 0.3% propionic acid, and 0.1% lauric arginate [LAE]) applied as dip treatments were evaluated in their efficacy in reducing S...
March 31, 2017: Poultry Science
https://www.readbyqxmd.com/read/28377846/a-quantitative-approach-to-predict-differential-effects-of-anti-vegf-treatment-on-diffuse-and-focal-leakage-in-patients-with-diabetic-macular-edema-a-pilot-study
#16
Michael J Allingham, Dibyendu Mukherjee, Erin B Lally, Hossein Rabbani, Priyatham S Mettu, Scott W Cousins, Sina Farsiu
PURPOSE: We use semiautomated segmentation of fluorescein angiography (FA) to determine whether anti-vascular endothelial growth factor (VEGF) treatment for diabetic macular edema (DME) differentially affects microaneurysm (MA)-associated leakage, termed focal leakage, versus non-MA-associated leakage, termed diffuse leakage. METHODS: We performed a retrospective study of 29 subjects treated with at least three consecutive injections of anti-VEGF agents for DME (mean 4...
March 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28376041/comparison-of-ganglion-cell-inner-plexiform-layer-thickness-by-cirrus-and-spectralis-optical-coherence-tomography-in-diabetic-macular-edema
#17
Julia Hafner, Sonja Prager, Jan Lammer, Katharina Kriechbaum, Christoph Scholda, Eleonore Pablik, Ursula Schmidt-Erfurth
PURPOSE: Reduced thickness of the ganglion cell inner plexiform layer indicates diabetic neurodegeneration and can be assessed by spectral domain optical coherence tomography. The authors investigated the comparability of ganglion cell inner plexiform layer measurements from two spectral domain optical coherence tomography devices in patients with diabetic macular edema (DME). METHODS: Analysis of optical coherence tomography data sets of eyes with and fellow eyes without DME...
April 3, 2017: Retina
https://www.readbyqxmd.com/read/28373302/predictors-for-symptomatic-intracranial-hemorrhage-after-endovascular-treatment-of-acute-ischemic-stroke
#18
Yonggang Hao, Dong Yang, Huaiming Wang, Wenjie Zi, Meng Zhang, Yu Geng, Zhiming Zhou, Wei Wang, Haowen Xu, Xiguang Tian, Penghua Lv, Yuxiu Liu, Yunyun Xiong, Xinfeng Liu, Gelin Xu
BACKGROUND AND PURPOSE: Symptomatic intracranial hemorrhage (SICH) pose a major safety concern for endovascular treatment of acute ischemic stroke. This study aimed to evaluate the risk and related factors of SICH after endovascular treatment in a real-world practice. METHODS: Patients with stroke treated with stent-like retrievers for recanalizing a blocked artery in anterior circulation were enrolled from 21 stroke centers in China. Intracranial hemorrhage was classified as symptomatic and asymptomatic ones according to Heidelberg Bleeding Classification...
April 3, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28372360/a-modular-high-throughput-in-vivo-screening-platform-based-on-chimeric-bacterial-receptors
#19
Christina E Lehning, Jan B Heidelberger, John Reinhard, Morten H H Nørholm, Roger R Draheim
Multidrug resistance (MDR) is a globally relevant problem that requires novel approaches. Two-component systems are a promising, yet untapped target for novel antibacterials. They are prevalent in bacteria and absent in mammals, and their activity can be modulated upon perception of various stimuli. Screening pre-existing compound libraries could reveal small molecules that inhibit stimulus-perception by virulence-modulating receptors, reduce signal output from essential receptors or identify artificial stimulatory ligands for novel SHKs that are involved in virulence...
April 7, 2017: ACS Synthetic Biology
https://www.readbyqxmd.com/read/28371957/-impact-of-anthropologic-psychiatry-on-psychiatrie-enquete-and-psychiatric-reform-in-west-germany
#20
Felicitas Söhner, Thomas Becker, Heiner Fangerau
Objectives Analysis of the perception of effects of anthropological psychiatry on the Psychiatrie-Enquete and psychiatric reform in the Federal Republic of Germany (West Germany). Methods Qualitative content analysis of expert interviews and systematic literature search. Results Literary sources and expert interviews point to the impact of the anthropologic concept on discourse on and approach to those suffering from mental illness. The attention focused on the visualisation of material-social and subjective living conditions of persons with mental illness...
April 3, 2017: Psychiatrische Praxis
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