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https://www.readbyqxmd.com/read/28210293/interstitial-lung-diseases-course-report
#1
EDITORIAL
Michael Kreuter, Sead Zeynel, Deebya Raj Mishra
ERS hosted a 3-day course on interstitial lung diseases in Heidelberg, Germany http://ow.ly/M8MD3021q6n.
September 2016: Breathe
https://www.readbyqxmd.com/read/28196482/effect-of-light-and-prey-availability-on-gene-expression-of-the-mixotrophic-chrysophyte-ochromonas-sp
#2
Alle A Y Lie, Zhenfeng Liu, Ramon Terrado, Avery O Tatters, Karla B Heidelberg, David A Caron
BACKGROUND: Ochromonas is a genus of mixotrophic chrysophytes that is found ubiquitously in many aquatic environments. Species in this genus can be important consumers of bacteria but vary in their ability to perform photosynthesis. We studied the effect of light and bacteria on growth and gene expression of a predominantly phagotrophic Ochromonas species. Axenic cultures of Ochromonas sp. were fed with heat-killed bacteria (HKB) and grown in constant light or darkness. RNA was extracted from cultures in the light or in the dark with HKB present (Light + HKB; Dark + HKB), and in the light after HKB were depleted (Light + depleted HKB)...
February 14, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28194523/-establishment-of-the-new-cross-sectional-field-of-pain-medicine-an-application-example-at-the-medical-faculty-of-heidelberg
#3
S Frankenhauser, T Böker-Blum, C Busch, C Berberich, A L Mihaljevic, M A Weigand, H J Bardenheuer, J Kessler
Studies from recent years paint a picture of qualitatively deficient treatment in pain medicine. In order to improve the situation knowledge on targeted diagnostics and effective therapy should be imparted at an early stage during undergraduate studies. For this reason the cross-sectional field Q14 - pain medicine was newly created in the revision of the medical physician licencing regulations. The Q14 was then established in a longitudinal, multidisciplinary form at the medical faculty in Heidelberg, whereby the complete Kern cycle was run through...
February 13, 2017: Der Schmerz
https://www.readbyqxmd.com/read/28190889/infertile-partners-coping-strategies-are-interrelated-implications-for-targeted-psychological-counseling
#4
L Volmer, S Rösner, B Toth, T Strowitzki, T Wischmann
Background Infertility patients often have high stress levels which, in some cases, represent a risk of developing depression or anxiety. The SCREENIVF questionnaire is a validated tool to evaluate such risks. Some coping strategies have been shown to be correlated with infertile couples' levels of stress. Determining which strategies are correlated with higher levels of risk for depression or anxiety could be useful to offer targeted psychological counseling to reduce the risk of depression or anxiety. Materials and Methods A total of 296 women and men who attended the Fertility Center at Heidelberg University Hospital completed the SCREENIVF questionnaire and the COMPI coping scales...
January 2017: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/28176013/impact-of-reproductive-factors-on-breast-cancer-subtypes-in-postmenopausal-women-a-retrospective-single-center-study
#5
Alexandra von Au, Mona Klotzbuecher, Lorenz Uhlmann, Mark Boudewijns, Laura Michel, Markus Wallwiener, Joerg Heil, Michael Golatta, Joachim Rom, Christof Sohn, Andreas Schneeweiss, Florian Schuetz, Christoph Domschke
PURPOSE: Some reproductive factors are well-known general risk factors for breast cancer (BC). On the other hand, BC subtypes also have a high prognostic value. Correlations, however, that link these risk factors to the development of a particular one of the different BC subtypes are still poorly understood. The primary objective of our study was to assess the influence of different reproductive factors (duration of breastfeeding, parity, and age at first childbirth) on pathological BC subtypes...
February 7, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28171871/effect-of-photodynamic-therapy-on-optical-coherence-tomography-angiography-in-eyes-with-chronic-central-serous-chorioretinopathy
#6
Yishuang Xu, Yu Su, Lu Li, Hang Qi, Hongmei Zheng, Changzheng Chen
PURPOSE: To analyze the use of optical coherence tomography angiography (OCTA) in order to observe the changes in chronic central serous chorioretinopathy (CCSC) after half-dose photodynamic therapy (PDT). METHODS: This is a retrospective study evaluating an imaging technique in a cohort of patients. Fundus photography, fluorescein angiography (FA), indocyanine green angiography (ICGA) (Heidelberg Spectralis, Heidelberg, Germany), OCT, and OCTA with the split-spectrum amplitude-decorrelation angiography algorithm (XR Optovue, Fremont, CA, USA) were performed prior to half-dose PDT...
February 8, 2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/28166840/app-based-serious-gaming-for-training-of-chest-tube-insertion-study-protocol-for-a-randomized-controlled-trial
#7
Mirco Friedrich, Christian Bergdolt, Patrick Haubruck, Thomas Bruckner, Karl-Friedrich Kowalewski, Beat Peter Müller-Stich, Michael C Tanner, Felix Nickel
BACKGROUND: Chest tube insertion is a standard intervention for management of various injuries of the thorax. Quick and accurate execution facilitates efficient therapy without further complications. Here, we propose a new training concept comprised of e-learning elements as well as continuous rating using an objective structured assessment of technical skills (OSATS) tool. The study protocol is presented for a randomized trial to evaluate e-learning with app-based serious gaming for chest drain insertion...
February 6, 2017: Trials
https://www.readbyqxmd.com/read/28151841/visualization-of-macular-pucker-by-multicolor-scanning-laser-imaging
#8
Ilkay Kilic Muftuoglu, Dirk-Uwe Bartsch, Giulio Barteselli, Raouf Gaber, Joseph Nezgoda, William R Freeman
PURPOSE: To compare the visualization of the epiretinal membrane (ERM) using multicolor imaging (MCI) (Heidelberg Engineering, Carlsbad, CA) and conventional white light flood color fundus photography (FP) (Topcon). METHODS: The paired images of patients with ERM who underwent same-day MCI and FP examinations were reviewed. Visibility of the ERM was graded using a scale (0: not visible, 1: barely visible, and 2: clearly visible) by masked readers, and surface folds were counted to quantify the membrane visibility for each method...
February 1, 2017: Retina
https://www.readbyqxmd.com/read/28137797/a-whole-genome-sequencing-approach-to-study-cefoxitin-resistant-salmonella-enterica-serovar-heidelberg-from-various-sources
#9
Romaine Edirmanasinghe, Rita Finley, E Jane Parmley, Brent P Avery, Carolee Carson, Sadjia Bekal, George Golding, Michael R Mulvey
This study characterized cefoxitin-resistant and susceptible Salmonella enterica serovar Heidelberg from human, abattoir poultry, and retail poultry to assess the molecular relationships of isolates from these sources in Québec in 2012. Isolates were collected as part of the Canadian Integrated Program for Antimicrobial Resistance Surveillance (CIPARS). All isolates were subjected to antimicrobial susceptibility testing, polymerase chain reaction (PCR) for CMY-2, pulsed-field gel electrophoresis (PFGE), and whole genome sequencing (WGS)...
January 30, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28133888/alterations-of-the-outer-retina-in-non-arteritic-anterior-ischemic-optic-neuropathy-detected-using-spectral-domain-optical-coherence-tomography
#10
Philipp Ackermann, Maike Brachert, Philipp Albrecht, Marius Ringelstein, David Finis, Gerd Geerling, Orhan Aktas, Rainer Guthoff
BACKGROUND: Changes in peripapillary and macular retinal layer thickness in non-arteritic anterior ischemic optic neuropathy (NAION) measured using spectral-domain optical coherence tomography may reflect a characteristic disease pattern. Advanced software enables retinal layer segmentation. In this study, we compared retinal layer thicknesses in acute and chronic NAION. DESIGN: A single-center cross-sectional analysis in a university clinic. PARTICIPANTS: 14 eyes with acute (<7 days) and 13 eyes with chronic NAION and 20 age-matched healthy eyes...
January 30, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28130350/in-vivo-confocal-microscopic-characteristics-of-microsporidial-keratoconjunctivitis-in-immunocompetent-adults
#11
Chintan Malhotra, Arun Kumar Jain, Savleen Kaur, Deepika Dhingra, Varshitha Hemanth, Surya Prakash Sharma
BACKGROUND/AIMS: To describe in vivo confocal microscopy (IVCM) features of microsporidial keratoconjunctivitis in immunocompetent adult patients. METHODS: Patients suspected clinically to be suffering from microsporidial keratoconjunctivitis (ie, presence of unilateral follicular and/or papillary conjunctivitis in conjunction with multifocal, coarse corneal epitheliopathy) were subjected to IVCM with the Rostock Cornea Module of the Heidelberg Retinal Tomograph 3, and combined potassium hydroxide and calcofluor white (KOH+CFW) staining of the corneal scrapings, to detect the microsporidial spores...
January 27, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28129741/life-space-and-movement-behavior-in-nursing-home-residents-results-of-a-new-sensor-based-assessment-and-associated-factors
#12
Carl-Philipp Jansen, Mona Diegelmann, Eva-Luisa Schnabel, Hans-Werner Wahl, Klaus Hauer
BACKGROUND: Studies on life-space (LS) and its determinants have previously been limited to community-dwelling subjects but are lacking in institutionalized older persons. The purpose of this study was to provide an advanced descriptive analysis of LS in nursing home residents and to identify associated factors based on an established theoretical framework, using an objective, sensor-based assessment with a high spatiotemporal resolution. METHODS: Cross-sectional study in two nursing homes in Heidelberg, Germany (n = 65; mean age: 82...
January 28, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28118692/intercollegiate-conversations-australian-and-new-zealand-college-of-anaesthetists
#13
Victor Lee, Ian S Graham
In the first of a series of online interviews with other Australian and New Zealand Specialty Colleges about the developments and shared challenges with implementing competency-based medical education, I spoke with the current Dean of Education at the Australian and New Zealand College of Anaesthetists, Dr Ian Graham. Dr Graham is not an anaesthetist. He is a Fellow of the Royal Australasian College of Medical Administrators, educator and consultant in health management. He was appointed into the role of part-time Dean of Education at the Australian and New Zealand College of Anaesthetists in August 2014...
January 24, 2017: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/28118204/can-glaucomatous-visual-field-progression-be-predicted-by-structural-and-functional-measures
#14
Wolfgang A Schrems, Laura-M Schrems-Hoesl, Christian Y Mardin, Robert Laemmer, Friedrich E Kruse, Folkert K Horn
PURPOSE: The aim of this study was to compare the predictive value of retinal nerve fiber layer thickness (RNFLT) measurements obtained by optical coherence tomography (OCT), morphometric parameters of confocal scanning laser ophthalmoscopy (CSLO), and frequency-doubling technique perimetry to predict visual field conversion of normal individuals, ocular hypertensive subjects, and early preperimetric glaucoma patients as determined by standard automated perimetry (SAP). PATIENTS AND METHODS: This longitudinal single-center study included 107 eyes of 56 controls, 164 eyes of 98 patients with ocular hypertension, and 169 eyes of 110 patients with preperimetric glaucoma...
January 23, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28117076/oct-angiography-of-acute-non-arteritic-anterior-ischemic-optic-neuropathy
#15
M-B Rougier, M-N Delyfer, J-F Korobelnik
PURPOSE: To describe changes of the retinal peripapillary microvasculature on optical coherence tomography angiography (OCT-A) in non-arteritic anterior ischemic optic (NAION) neuropathy. METHODS: Observational study of 10 patients at the acute phase of NAION. OCT-A was performed using a 3mm×3mm square centered on the optic disc (Cirrus HD-OCT with Angioplex, Carl Zeiss Meditec, Dublin, CA). A qualitative comparison was made with the healthy fellow eye of each patient...
February 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28114125/fragmentation-of-120-and-200-mev-u-1-4-he-ions-in-water-and-pmma-targets
#16
M Rovituso, C Schuy, U Weber, S Brons, M A Cortés-Giraldo, C La Tessa, E Piasetzky, D Izraeli, D Schardt, M Toppi, E Scifoni, M Krämer, M Durante
Recently, the use of (4)He particles in cancer radiotherapy has been reconsidered as they potentially represent a good compromise between protons and (12)C ions. The first step to achieve this goal is the development of a dedicated treatment planning system, for which basic physics information such as the characterization of the beam lateral scattering and fragmentation cross sections are required. In the present work, the attenuation of (4)He primary particles and the build-up of secondary charged fragments at various depths in water and polymethyl methacrylate were investigated experimentally for 120 and 200 MeV u(-1) beams delivered by the synchrotron at the Heidelberg Ion-Beam Therapy Center, Heidelberg...
February 21, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28114124/secondary-radiation-measurements-for-particle-therapy-applications-nuclear-fragmentation-produced-by-4-he-ion-beams-in-a-pmma-target
#17
M Marafini, R Paramatti, D Pinci, G Battistoni, F Collamati, E De Lucia, R Faccini, P M Frallicciardi, C Mancini-Terracciano, I Mattei, S Muraro, L Piersanti, M Rovituso, A Rucinski, A Russomando, A Sarti, A Sciubba, E Solfaroli Camillocci, M Toppi, G Traini, C Voena, V Patera
Nowadays there is a growing interest in particle therapy treatments exploiting light ion beams against tumors due to their enhanced relative biological effectiveness and high space selectivity. In particular promising results are obtained by the use of (4)He projectiles. Unlike the treatments performed using protons, the beam ions can undergo a fragmentation process when interacting with the atomic nuclei in the patient body. In this paper the results of measurements performed at the Heidelberg Ion-Beam Therapy center are reported...
February 21, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28114112/secondary-radiation-measurements-for-particle-therapy-applications-prompt-photons-produced-by-4-he-12-c-and-16-o-ion-beams-in-a-pmma-target
#18
I Mattei, F Bini, F Collamati, E De Lucia, P M Frallicciardi, E Iarocci, C Mancini-Terracciano, M Marafini, S Muraro, R Paramatti, V Patera, L Piersanti, D Pinci, A Rucinski, A Russomando, A Sarti, A Sciubba, E Solfaroli Camillocci, M Toppi, G Traini, C Voena, G Battistoni
Charged particle beams are used in particle therapy (PT) to treat oncological patients due to their selective dose deposition in tissues with respect to the photons and electrons used in conventional radiotherapy. Heavy (Z  >  1) PT beams can additionally be exploited for their high biological effectiveness in killing cancer cells. Nowadays, protons and carbon ions are used in PT clinical routines. Recently, interest in the potential application of helium and oxygen beams has been growing. With respect to protons, such beams are characterized by their reduced multiple scattering inside the body, increased linear energy transfer, relative biological effectiveness and oxygen enhancement ratio...
February 21, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28113877/automated-diagnosis-of-glaucoma-using-empirical-wavelet-transform-and-correntropy-features-extracted-from-fundus-images
#19
Shishir Maheshwari, Ram Bilas Pachori, U Rajendra Acharya
Glaucoma is an ocular disorder caused due to increased fluid pressure in the optic nerve. It damages the optic nerve subsequently causes loss of vision. The available scanning methods are Heidelberg Retinal Tomography (HRT), Scanning Laser Polarimetry (SLP) and Optical Coherence Tomography (OCT). These methods are expensive and require experienced clinicians to use them. So, there is a need to diagnose glaucoma accurately with low cost. Hence, in this paper, we have presented a new methodology for an automated diagnosis of glaucoma using digital fundus images based on Empirical Wavelet Transform (EWT)...
March 22, 2016: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28110433/a-comprehensive-analysis-of-cardiac-valve-plane-displacement-in-healthy-adults-age-stratified-normal-values-by-cardiac-magnetic-resonance
#20
Marco M Ochs, Thomas Fritz, Florian André, Johannes Riffel, Derliz Mereles, Matthias Müller-Hennessen, Evangelos Giannitsis, Hugo A Katus, Matthias G Friedrich, Sebastian J Buss
Cardiac valve plane displacement (CVPD) reflects longitudinal LV function. The purpose of the present study was to determine regional heterogeneity of CVPD in healthy adults to provide normal values by cardiac magnetic resonance (CMR). We measured the anterior aortic plane systolic excursion (AAPSE); the anterior, anterolateral, inferolateral, inferior, and inferoseptal mitral annular plane systolic excursion (MAPSE); and the lateral tricuspid annulus plane systolic excursion (TAPSE). Systolic excursion was measured as the distance from peak end-diastolic to peak end-sysstolic annular position (peak-to-peak) in cine images acquired in 2-, 3- and 4-chamber views...
January 21, 2017: International Journal of Cardiovascular Imaging
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