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Volumetric laser endomicroscopy

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https://www.readbyqxmd.com/read/28927838/use-of-volumetric-laser-endomicroscopy-to-characterize-a-duodenal-neuroendocrine-tumor
#1
Amrit K Kamboj, Prasuna Muppa, Liam Zakko, Kenneth K Wang, Cadman L Leggett
No abstract text is available yet for this article.
September 16, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28922442/volumetric-laser-endomicroscopy-for-barrett-s-esophagus-looking-at-the-fine-print
#2
REVIEW
Deepanshu Jain, Sanna Fatima, Shilpa Jain, Shashideep Singhal
Barrett's esophagus (BE) is a premalignant condition. The incidence of adenocarcinoma in BE has been reported to be between 0.1-3%. Dysplasia in BE is patchy and extensive biopsy sampling is labor intensive, low yield and does not eliminate the sampling error completely. Volumetric laser endomicroscopy (VLE) is expected to enable endoscopists to do targeted biopsy of dysplastic/cancerous lesions (not visible on white light endoscopy) among patients with BE. We reviewed 7 studies with a total of 62 subjects who had undergone VLE...
September 2017: Journal of Gastrointestinal and Liver Diseases: JGLD
https://www.readbyqxmd.com/read/28803742/gastric-cardia-lesion-with-abnormal-volumetric-laser-endomicroscopy-imaging
#3
Nina Gupta, Vani Konda, Uzma Siddiqui
No abstract text is available yet for this article.
August 10, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28777838/quantitative-attenuation-analysis-for-identification-of-early-barrett-s-neoplasia-in-volumetric-laser-endomicroscopy
#4
Anne-Fre Swager, Dirk J Faber, Daniel M de Bruin, Bas L Weusten, Sybren L Meijer, Jacques J Bergman, Wouter L Curvers, Ton G van Leeuwen
Early neoplasia in Barrett’s esophagus (BE) is difficult to detect. Volumetric laser endomicroscopy (VLE) incorporates optical coherence tomography, providing a circumferential scan of the esophageal wall layers. The attenuation coefficient (μVLE) quantifies decay of detected backscattered light versus depth, and could potentially improve BE neoplasia detection. The aim is to investigate feasibility of μVLE for identification of early BE neoplasia. In vivo and ex vivo VLE scans with histological correlation from BE patients ± neoplasia were used...
August 1, 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/28617072/evaluation-of-ninepoint-medical-s-nvision-vle-device-for-gastrointestinal-applications
#5
Jeffrey D Mosko, Douglas Pleskow
The incidence of esophageal adenocarcinoma (EAC) has increased over the last few decades. With a known precursor lesion, Barrett's esophagus, this remains a target for screening and surveillance with the goal of detecting and providing curative treatment for early neoplasia. Areas covered: Current surveillance techniques rely on white light endoscopy and random tissue sampling which is time consuming, costly and prone to sampling error. Volumetric laser endomicroscopy (VLE), a second-generation optical coherence technology, has emerged as an advanced imaging modality with the potential to improve dysplasia detection, surveillance and subsequently prevent esophageal adenocarcinoma...
June 22, 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28611477/a-guide-to-multimodal-endoscopy-imaging-for-gastrointestinal-malignancy-an-early-indicator
#6
REVIEW
Arthur Hoffman, Henrik Manner, Johannes W Rey, Ralf Kiesslich
Multimodality imaging is an essential aspect of endoscopic surveillance for the detection of neoplastic lesions, such as dysplasia or intramucosal cancer, because it improves the efficacy of endoscopic surveillance and therapeutic procedures in the gastrointestinal tract. This approach reveals mucosal abnormalities that cannot be detected by standard endoscopy. Currently, these imaging techniques are divided into those for primary detection and those for targeted imaging and characterization, the latter being used to visualize areas of interest in detail and permit histological evaluation...
July 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28577765/the-role-of-adjunct-imaging-in-endoscopic-detection-of-dysplasia-in-barrett-s-esophagus
#7
REVIEW
Pujan Kandel, Michael B Wallace
Advances in imaging technologies have demonstrated promise in early detection of dysplasia and cancer in Barrett's esophagus (BE). Optical chromoendoscopy, dye-based chromoendoscopy, and novel technologies have provided the opportunity to visualize the cellular and subcellular structures. Only narrow-band imaging and acetic acid chromoendoscopy have reached benchmarks for clinical use. Volumetric laser endomicroscopy and molecular imaging are not established for routine use. Best practice in management of BE should be focused on careful endoscopic examination, resection, or ablation of the entire abnormal lesion, as well as the use of available imaging technique that has good diagnostic accuracy...
July 2017: Gastrointestinal Endoscopy Clinics of North America
https://www.readbyqxmd.com/read/28446997/endoscopic-submucosal-dissection-and-endoscopic-mucosal-resection-for-early-stage-esophageal-cancer
#8
REVIEW
Bo Ning, Mohamed M Abdelfatah, Mohamed O Othman
Mortality from esophageal cancer remains high despite advances in medical therapy. Although the incidence of squamous cell carcinoma of the esophagus remains unchanged, the incidence of the esophageal adenocarcinoma has increased over time. Gastroesophageal reflux disease (GERD and obesity are contributing factors to the development of Barrett's esophagus and subsequent development of adenocarcinoma. Early recognition of the disease can lead to resection of esophageal cancer prior to the development of lymphovascular invasion...
March 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28402993/volumetric-laser-endomicroscopy-in-the-management-of-barrett-s-esophagus
#9
Arvind J Trindade, Cadman L Leggett, Kenneth J Chang
PURPOSE OF REVIEW: The incidence of esophageal adenocarcinoma is on the rise despite widespread appreciation that the precursor lesion is Barrett's esophagus. Studies have shown that some patients known to have Barrett's esophagus develop cancer despite their enrollment in conventional endoscopic surveillance programs. This highlights the need for advanced endoscopic imaging to help identify early neoplasia and prevent its progression to esophageal cancer. Recently, a wide-field, second-generation optical coherence tomography endoscopic platform called volumetric laser endomicroscopy (VLE) was cleared by the Food and Drug Administration and made commercially available for advanced imaging in Barrett's esophagus...
July 2017: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/28322771/computer-aided-detection-of-early-barrett-s-neoplasia-using-volumetric-laser-endomicroscopy
#10
A Swager, F van der Sommen, S R Klomp, S Zinger, S L Meijer, E J Schoon, J J Bergman, P H N de With, W L Curvers
BACKGROUND AND AIMS: Volumetric laser endomicroscopy (VLE) is an advanced imaging system that provides a near-microscopic resolution scan of the esophageal wall layers up to 3 mm deep. VLE has the potential to improve detection of early neoplasia in Barrett's esophagus (BE). However, interpretation of VLE images is complex due to the large amount of data that needs to be interpreted in real-time. The aim of this study was to investigate the feasibility of a computer algorithm to identify early BE neoplasia on ex vivo VLE images...
March 16, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28256346/past-present-and-future-of-barrett-s-oesophagus
#11
REVIEW
W K Tan, M di Pietro, R C Fitzgerald
Barrett's oesophagus is a condition which predisposes towards development of oesophageal adenocarcinoma, a highly lethal tumour which has been increasing in incidence in the Western world over the past three decades. There have been tremendous advances in the field of Barrett's oesophagus, not only in diagnostic modalities, but also in therapeutic strategies available to treat this premalignant disease. In this review, we discuss the past, present and future of Barrett's oesophagus. We describe the historical and new evolving diagnostic criteria of Barrett's oesophagus, while also comparing and contrasting the British Society of Gastroenterology guidelines, American College of Gastroenterology guidelines and International Benign Barrett's and CAncer Taskforce (BOBCAT) for Barrett's oesophagus...
July 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28161451/feasibility-of-laser-marking-in-barrett-s-esophagus-with-volumetric-laser-endomicroscopy-first-in-man-pilot-study
#12
A Swager, A J de Groof, S L Meijer, B L Weusten, W L Curvers, Jacques J Bergman
BACKGROUND AND AIM: Volumetric laser endomicroscopy (VLE) provides a circumferential scan of the esophageal wall layers and has potential to improve detection of neoplasia in Barrett's esophagus (BE). The novel VLE laser marking system enables direct in vivo marking of suspicious areas as identified on VLE. These laser marked areas can subsequently be targeted for biopsies. The aim was to evaluate the visibility and positional accuracy of laser marks (LMs) in different esophageal tissue types on white light endoscopy (WLE) and VLE...
February 2, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28068705/targeting-neoplasia-using-volumetric-laser-endomicroscopy-with-laser-marking
#13
Arvind J Trindade, Sumant Inamdar, Divyesh V Sejpal, Arvind Rishi, Keith Sultan
No abstract text is available yet for this article.
February 2017: Endoscopy
https://www.readbyqxmd.com/read/28035200/volumetric-laser-endomicroscopy-in-patients-with-barrett-esophagus
#14
Herbert C Wolfsen
No abstract text is available yet for this article.
November 2016: Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27899321/volumetric-laser-endomicroscopy-in-barrett-s-esophagus-interobserver-agreement-for-interpretation-of-barrett-s-esophagus-and-associated-neoplasia-among-high-frequency-users
#15
Arvind J Trindade, Sumant Inamdar, Michael S Smith, Kenneth J Chang, Cadman L Leggett, Charles J Lightdale, Douglas K Pleskow, Divyesh V Sejpal, Guillermo J Tearney, Rebecca M Thomas, Michael B Wallace
BACKGROUND AND AIMS: Targeting neoplasia in Barrett's esophagus (BE) is challenging. Volumetric laser endomicroscopy (VLE) is a new imaging technique that allows for real time cross-sectional microstructure imaging that can detect BE neoplasia. The interobserver agreement among users in practice is unknown. METHODS: Eight high-volume users of VLE from different academic centers in the United States evaluated 120 stored VLE images blinded to the endoscopic and clinical findings...
November 27, 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27658906/identification-of-volumetric-laser-endomicroscopy-features-predictive-for-early-neoplasia-in-barrett-s-esophagus-using-high-quality-histological-correlation
#16
Anne-Fré Swager, Guillermo J Tearney, Cadman L Leggett, Martijn G H van Oijen, Sybren L Meijer, Bas L Weusten, Wouter L Curvers, Jacques J G H M Bergman
BACKGROUND AND AIMS: Volumetric laser endomicroscopy (VLE) provides a circumferential scan that enables visualization of the subsurface layers of the esophageal wall at 7 μm resolution. The aims of this study were to identify VLE features of Barrett's esophagus (BE) neoplasia and to develop a VLE prediction score. METHODS: A database of VLE images from endoscopic resection specimens, precisely correlated with histology, from patients with BE with and without neoplasia was used...
May 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27134668/the-new-kid-on-the-block-for-advanced-imaging-in-barrett-s-esophagus-a-review-of-volumetric-laser-endomicroscopy
#17
REVIEW
Arvind J Trindade, Michael S Smith, Douglas K Pleskow
Advanced imaging techniques used in the management of Barrett's esophagus include electronic imaging enhancement (e.g. narrow band imaging, flexible spectral imaging color enhancement, and i-Scan), chromoendoscopy, and confocal laser endomicroscopy. Electronic imaging enhancement is used frequently in daily practice, but use of the other advanced technologies is not routine. High-definition white light endoscopy and random four quadrant biopsy remain the standard of care for evaluation of Barrett's esophagus; this is largely due to the value of advanced imaging technologies not having been validated in large studies or in everyday practice...
May 2016: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/27009460/advances-in-the-endoscopic-diagnosis-of-barrett-esophagus
#18
REVIEW
Ashley H Davis-Yadley, Kevin G Neill, Mokenge P Malafa, Luis R Pena
BACKGROUND: Barrett esophagus (BE) continues to be a major risk factor for developing esophageal adenocarcinoma. METHODS: We review the risk factors, diagnosis, and management of BE, with an emphasis on the most current endoscopic diagnostic modalities for BE. RESULTS: Novel diagnostic modalities have emerged to address the inadequacies of standard, untargeted biopsies, such as dye-based and virtual chromoendoscopy, endoscopic mucosal resection, molecular biomarkers, optical coherence tomography, confocal laser endomicroscopy, volumetric laser endomicroscopy, and endocytoscopy...
January 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27004250/volumetric-laser-endomicroscopy-can-target-neoplasia-not-detected-by-conventional-endoscopic-measures-in-long-segment-barrett-s-esophagus
#19
Arvind J Trindade, Benley J George, Joshua Berkowitz, Divyesh V Sejpal, Matthew J McKinley
Methods and study aims: The incidence of esophageal cancer is rising despite increased surveillance efforts. Volumetric laser endomicroscopy (VLE) is a new endoscopic imaging tool that can allow for targeted biopsy of neoplasia in Barrett's esophagus. We report a series of 6 patients with long-segment Barrett's esophagus ( > 3 cm), who underwent a session of endoscopy with volumetric laser endomicroscopy, after a separate prior session of standard high-definition endoscopy with narrow band imaging (NBI) and random biopsies that did not reveal neoplasia...
March 2016: Endoscopy International Open
https://www.readbyqxmd.com/read/26989033/use-of-volumetric-laser-endomicroscopy-in-staging-multifocal-superficial-squamous-carcinoma-of-the-esophagus
#20
Arvind J Trindade, Arvind Rishi, Peter H Stein, Divyesh V Sejpal
No abstract text is available yet for this article.
August 2016: Gastrointestinal Endoscopy
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