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Volumetric laser endomicroscopy

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https://www.readbyqxmd.com/read/27899321/volumetric-laser-endomicroscopy-in-barrett-s-esophagus-interobserver-agreement-for-interpretation-of-barrett-s-esophagus-and-associated-neoplasia-among-high-frequency-users
#1
Arvind J Trindade, Sumant Inamdar, Michael S Smith, Kenneth J Chang, Cadman L Leggett, Charles J Lightdale, Douglas K Pleskow, Divyesh V Sejpal, Guillermo J Tearney, Rebecca M Thomas, Michael B Wallace
BACKGROUND AND AIMS: Targeting neoplasia in Barrett's esophagus (BE) is challenging. Volumetric laser endomicroscopy (VLE) is a new imaging technique that allows for real time cross-sectional microstructure imaging that can detect BE neoplasia. The interobserver agreement among users in practice is unknown. METHODS: Eight high-volume users of VLE from different academic centers in the United States evaluated 120-stored VLE images blinded to the endoscopic and clinical findings...
November 26, 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27658906/identification-of-volumetric-laser-endomicroscopy-features-predictive-for-early-neoplasia-in-barrett-s-esophagus-using-high-quality-histological-correlation
#2
A Swager, G J Tearney, C L Leggett, M G H van Oijen, S L Meijer, B L Weusten, W L Curvers, J J Bergman
BACKGROUND AND AIMS: Volumetric laser endomicroscopy (VLE) provides a circumferential scan that enables visualization of the subsurface layers of the esophageal wall at 7 μm resolution. The aims of this study were to identify VLE features of Barrett's esophagus (BE) neoplasia and to develop a VLE prediction score. METHODS: A database of VLE images from endoscopic resection specimens, precisely correlated with histology, from patients with BE with and without neoplasia was used...
September 19, 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27134668/the-new-kid-on-the-block-for-advanced-imaging-in-barrett-s-esophagus-a-review-of-volumetric-laser-endomicroscopy
#3
REVIEW
Arvind J Trindade, Michael S Smith, Douglas K Pleskow
Advanced imaging techniques used in the management of Barrett's esophagus include electronic imaging enhancement (e.g. narrow band imaging, flexible spectral imaging color enhancement, and i-Scan), chromoendoscopy, and confocal laser endomicroscopy. Electronic imaging enhancement is used frequently in daily practice, but use of the other advanced technologies is not routine. High-definition white light endoscopy and random four quadrant biopsy remain the standard of care for evaluation of Barrett's esophagus; this is largely due to the value of advanced imaging technologies not having been validated in large studies or in everyday practice...
May 2016: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/27009460/advances-in-the-endoscopic-diagnosis-of-barrett-esophagus
#4
Ashley H Davis-Yadley, Kevin G Neill, Mokenge P Malafa, Luis R Pena
BACKGROUND: Barrett esophagus (BE) continues to be a major risk factor for developing esophageal adenocarcinoma. METHODS: We review the risk factors, diagnosis, and management of BE, with an emphasis on the most current endoscopic diagnostic modalities for BE. RESULTS: Novel diagnostic modalities have emerged to address the inadequacies of standard, untargeted biopsies, such as dye-based and virtual chromoendoscopy, endoscopic mucosal resection, molecular biomarkers, optical coherence tomography, confocal laser endomicroscopy, volumetric laser endomicroscopy, and endocytoscopy...
January 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27004250/volumetric-laser-endomicroscopy-can-target-neoplasia-not-detected-by-conventional-endoscopic-measures-in-long-segment-barrett-s-esophagus
#5
Arvind J Trindade, Benley J George, Joshua Berkowitz, Divyesh V Sejpal, Matthew J McKinley
Methods and study aims: The incidence of esophageal cancer is rising despite increased surveillance efforts. Volumetric laser endomicroscopy (VLE) is a new endoscopic imaging tool that can allow for targeted biopsy of neoplasia in Barrett's esophagus. We report a series of 6 patients with long-segment Barrett's esophagus ( > 3 cm), who underwent a session of endoscopy with volumetric laser endomicroscopy, after a separate prior session of standard high-definition endoscopy with narrow band imaging (NBI) and random biopsies that did not reveal neoplasia...
March 2016: Endoscopy International Open
https://www.readbyqxmd.com/read/26989033/use-of-volumetric-laser-endomicroscopy-in-staging-multifocal-superficial-squamous-carcinoma-of-the-esophagus
#6
Arvind J Trindade, Arvind Rishi, Peter H Stein, Divyesh V Sejpal
No abstract text is available yet for this article.
August 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/26976783/volumetric-laser-endomicroscopy-in-the-detection-of-neoplastic-lesions-of-the-esophagus
#7
Christopher Atkinson, Satish Singh, P Marco Fisichella
No abstract text is available yet for this article.
June 2016: Digestive and Liver Disease
https://www.readbyqxmd.com/read/26770274/successful-use-of-volumetric-laser-endomicroscopy-in-imaging-a-rectal-polyp
#8
Arvind J Trindade, Keith Sultan, Arunan S Vamadevan, Cathy Fan, Divyesh V Sejpal
No abstract text is available yet for this article.
January 2016: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/26344884/comparative-diagnostic-performance-of-volumetric-laser-endomicroscopy-and-confocal-laser-endomicroscopy-in-the-detection-of-dysplasia-associated-with-barrett-s-esophagus
#9
Cadman L Leggett, Emmanuel C Gorospe, Daniel K Chan, Prasuna Muppa, Victoria Owens, Thomas C Smyrk, Marlys Anderson, Lori S Lutzke, Guillermo Tearney, Kenneth K Wang
BACKGROUND AND AIMS: Probe-based confocal laser endomicroscopy (pCLE) and volumetric laser endomicroscopy (VLE) (also known as frequency domain optical coherence tomography) are advanced endoscopic imaging modalities that may be useful in the diagnosis of dysplasia associated with Barrett's esophagus (BE). We performed pCLE examination in ex-vivo EMR specimens and compared the diagnostic performance of using the current VLE scoring index (previously established as OCT-SI) and a novel VLE diagnostic algorithm (VLE-DA) for the detection of dysplasia...
May 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/26124075/detection-of-buried-barrett-s-glands-after-radiofrequency-ablation-with-volumetric-laser-endomicroscopy
#10
Anne-Fré Swager, David F Boerwinkel, Daniel M de Bruin, Dirk J Faber, Ton G van Leeuwen, Bas L Weusten, Sybren L Meijer, Jacques J Bergman, Wouter L Curvers
BACKGROUND AND AIMS: The prevalence and clinical relevance of buried Barrett's glands (BB) after radiofrequency ablation (RFA) in Barrett's esophagus (BE) are debated. Recent optical coherence tomography studies demonstrated a high prevalence of BBs. Direct histological correlation, however, has been lacking. Volumetric laser endomicroscopy (VLE) is a second-generation optical coherence tomography system capable of scanning a large surface of the esophageal wall layers with low-power microscopy resolution...
January 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/26005011/finding-a-needle-in-a-haystack-use-of-volumetric-laser-endomicroscopy-in-targeting-focal-dysplasia-in-long-segment-barrett-s-esophagus
#11
Arvind J Trindade, Arunan S Vamadevan, Divyesh V Sejpal
No abstract text is available yet for this article.
October 2015: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/25956472/safety-and-feasibility-of-volumetric-laser-endomicroscopy-in-patients-with-barrett-s-esophagus-with-videos
#12
MULTICENTER STUDY
Herbert C Wolfsen, Prateek Sharma, Michael B Wallace, Cadman Leggett, Guillermo Tearney, Kenneth K Wang
BACKGROUND: Volumetric laser endomicroscopy (VLE) produces high-resolution, cross-sectional surface, and subsurface images for detecting neoplasia, targeting biopsies, and guiding real-time treatment. OBJECTIVE: To evaluate the safety and feasibility of the Nvision VLE system. DESIGN: Prospective, multicenter study. SETTING: Tertiary-care medical centers. PATIENTS: One hundred patients with suspected Barrett's esophagus, including 52 patients with prior endotherapy...
October 2015: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/25951873/volumetric-laser-endomicroscopy-in-barrett-s-esophagus-a-feasibility-study-on-histological-correlation
#13
A Swager, D F Boerwinkel, D M de Bruin, B L Weusten, D J Faber, S L Meijer, T G van Leeuwen, W L Curvers, J J Bergman
Volumetric laser endomicroscopy (VLE) is a novel balloon-based optical coherence tomography (OCT) imaging technique that may improve detection of early neoplasia in Barrett's esophagus (BE). Most OCT studies lack a direct correlation between histology and OCT images. The aim is to investigate the optimal approach for achieving one-to-one correlation of ex-vivo VLE images of endoscopic resection (ER) specimens with histology. BE patients with and without early neoplasia underwent ER after delineating areas with electrocoagulation markers (ECM)...
August 2016: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/24462171/esophageal-guided-biopsy-with-volumetric-laser-endomicroscopy-and-laser-cautery-marking-a-pilot-clinical-study
#14
Melissa J Suter, Michalina J Gora, Gregory Y Lauwers, Thomas Arnason, Jenny Sauk, Kevin A Gallagher, Lauren Kava, Khay M Tan, Amna R Soomro, Timothy P Gallagher, Joseph A Gardecki, Brett E Bouma, Mireille Rosenberg, Norman S Nishioka, Guillermo J Tearney
BACKGROUND: Biopsy surveillance protocols for the assessment of Barrett's esophagus can be subject to sampling errors, resulting in diagnostic uncertainty. Optical coherence tomography is a cross-sectional imaging technique that can be used to conduct volumetric laser endomicroscopy (VLE) of the entire distal esophagus. We have developed a biopsy guidance platform that places endoscopically visible marks at VLE-determined biopsy sites. OBJECTIVE: The objective of this study was to demonstrate in human participants the safety and feasibility of VLE-guided biopsy in vivo...
June 2014: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/23735102/optical-coherence-tomography-in-barrett-s-esophagus
#15
REVIEW
Charles J Lightdale
The incidence of Barrett's-related adenocarcinoma of the esophagus continues to increase at an alarming rate. Studies to date show great promise for optical coherence tomography (OCT) in screening, surveillance, and guiding management of Barrett's esophagus. With continued innovation in rapid, accurate scanning systems, such as volumetric laser endomicroscopy or optical frequency domain imaging, advanced OCT seems likely to have an important impact. The next few years are likely to see the initiation of large clinical studies that will define the extent and significance of this impact...
July 2013: Gastrointestinal Endoscopy Clinics of North America
https://www.readbyqxmd.com/read/22889003/optical-endomicroscopy-and-the-road-to-real-time-in-vivo-pathology-present-and-future
#16
REVIEW
Charles S Carignan, Yukako Yagi
Epithelial cancers account for substantial mortality and are an important public health concern. With the need for earlier detection and treatment of these malignancies, the ability to accurately detect precancerous lesions has an increasingly important role in controlling cancer incidence and mortality. New optical technologies are capable of identifying early pathology in tissues or organs in which cancer is known to develop through stages of dysplasia, including the esophagus, colon, pancreas, liver, bladder, and cervix...
2012: Diagnostic Pathology
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