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https://www.readbyqxmd.com/read/27912983/hypertrophic-obstructive-cardiomyopathy
#1
REVIEW
Josef Veselka, Nandan S Anavekar, Philippe Charron
Hypertrophic obstructive cardiomyopathy is an inherited myocardial disease defined by cardiac hypertrophy (wall thickness ≥15 mm) that is not explained by abnormal loading conditions, and left ventricular obstruction greater than or equal to 30 mm Hg. Typical symptoms include dyspnoea, chest pain, palpitations, and syncope. The diagnosis is usually suspected on clinical examination and confirmed by imaging. Some patients are at increased risk of sudden cardiac death, heart failure, and atrial fibrillation...
November 29, 2016: Lancet
https://www.readbyqxmd.com/read/27910083/radiofrequency-catheter-ablation-of-accessory-pathways-in-patients-with-ebstein-s-anomaly-at-8-years-of-follow-up
#2
Michał Orczykowski, Paweł Derejko, Robert Bodalski, Piotr Urbanek, Joanna Zakrzewska-Koperska, Radosław Sierpiński, Katarzyna Kalin, Andrzej Hasiec, Grzegorz Warmiński, Maria Miszczak-Knecht, Katarzyna Bieganowska, Rafał Baranowski, Maria Bilińska, Elżbieta Biernacka, Piotr Hoffman, Łukasz Szumowski
BACKGROUND: Data regarding long-term follow-up of radiofrequency catheter ablation (RFCA) of accessory pathways (APs) in patients with Ebstein's anomaly (EA) are limited. The procedures are challenging due to multiple or wide APs. METHODS: Analysis was performed on clinical and periprocedural data of patients with EA referred to the centre in order to perform catheter ablation of accessory pathway (AP). The group consisted of 22 patients (female 40.9%, mean age 33...
December 2, 2016: Cardiology Journal
https://www.readbyqxmd.com/read/27893055/assessment-of-use-vs-discontinuation-of-oral-anticoagulation-after-pulmonary-vein-isolation-in-patients-with-atrial-fibrillation
#3
Sara Själander, Fredrik Holmqvist, J Gustav Smith, Pyotr G Platonov, Milos Kesek, Peter J Svensson, Carina Blomström-Lundqvist, Fariborz Tabrizi, Jari Tapanainen, Dritan Poci, Anders Jönsson, Anders Själander
Importance: Pulmonary vein isolation (PVI) is a recommended treatment for patients with atrial fibrillation, but it is unclear whether it results in a lower risk of stroke. Objectives: To investigate the proportion of patients discontinuing anticoagulation treatment after PVI in association with the CHA2DS2-VASc (congestive heart failure, hypertension, age ≥75 years [doubled], diabetes, stroke [doubled], vascular disease, age 65-74 years, sex category [female]) score, identify factors predicting stroke after PVI, and explore the risk of cardiovascular events after PVI in patients with and without guideline-recommended anticoagulation treatment...
November 23, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/27886924/how-to-improve-cardiac-resynchronization-therapy-benefit-in-atrial-fibrillation-patients-pulmonary-vein-isolation-and-beyond
#4
REVIEW
Carola Gianni, Luigi Di Biase, Sanghamitra Mohanty, Yalçın Gökoğlan, Mahmut Fatih Güneş, Amin Al-Ahmad, J David Burkhardt, Andrea Natale
Although cardiac resynchronization therapy (CRT) is an important treatment of symptomatic heart failure patients in sinus rhythm with low left ventricular ejection fraction and ventricular dyssynchrony, its role is not well defined in patients with atrial fibrillation (AF). CRT is not as effective in patients with AF because of inadequate biventricular capture and loss of atrioventricular synchrony. Both can be addressed with catheter ablation of AF. It is still unclear if these therapies offer additive benefits in patients with ventricular dyssynchrony...
January 2017: Heart Failure Clinics
https://www.readbyqxmd.com/read/27886923/atrioventricular-node-ablation
#5
REVIEW
Maurizio Gasparini
Cardiac resynchronization therapy (CRT) is a device-based, nonpharmacologic approach that has shown to improve the outcome in patients with heart failure in terms of mortality and morbidity reduction. Large randomized trials have virtually enrolled patients in New York Heart Association class III-IV, with reduced left ventricular ejection fraction, with evidence of electrical dyssynchrony, and receiving optimal medical therapy and who were in sinus rhythm. Guidelines remain imprecise as to defining differentiated approaches according to the forms of atrial fibrillation other than permanent...
January 2017: Heart Failure Clinics
https://www.readbyqxmd.com/read/27873022/current-rare-indications-and-future-directions-for-implantable-loop-recorders
#6
Simon Wechselberger, Christopher Piorkowski, Matthias Pohl
The scope of application for implantable loop recorders has shifted away from the evaluation of unclear palpitations and syncope episodes to more complex conditions. This article focuses on rare indications of growing importance such as rhythm monitoring after ablation of atrial fibrillation or after cryptogenic stroke. Furthermore, forthcoming applications in various clinical settings are described, e. g., arrhythmia detection after myocardial infarction, after catheter-based valve interventions, in heart failure, and in cardiomyopathies...
December 2016: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/27807090/surgical-ablation-of-atrial-fibrillation-a-protocol-for-a-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#7
Graham R McClure, Emilie P Belley-Cote, Rohit K Singal, Iqbal H Jaffer, Nazari Dvirnik, Kevin R An, Gabriel Fortin, Jessica Spence, Richard P Whitlock
INTRODUCTION: Atrial fibrillation (AF) affects 10% of patients undergoing cardiac surgery and is an independent risk factor for all-cause mortality, ischaemic stroke and heart failure. Surgical AF ablation has been shown to significantly improve maintenance of sinus rhythm, however, small to medium size trials conducted to date lack the power required to assess patient-important outcomes such as mortality, stroke, heart failure and health-related quality of life. Moreover, a recent randomised trial (RCT) suggested harm by surgical AF ablation with an almost threefold increase in the requirement for permanent pacemaker postablation...
November 2, 2016: BMJ Open
https://www.readbyqxmd.com/read/27802430/prognostic-value-of-red-blood-cell-distribution-width-on-bleeding-events-in-nonvalvular-atrial-fibrillation-patients-taking-dabigatran-110-mg-b-i-d-after-catheter-ablation
#8
Qing Zhang, Yao Qin, Dong-Sheng Zhao, Hai-Ping Zhao, Lei Zhou
OBJECTIVES: Recent research has indicated that red blood cell distribution width (RDW) is associated with the prognosis of cardiovascular diseases such as chronic heart failure and coronary heart disease. We aimed to study the predictive value of RDW for bleeding events in patients with nonvalvular atrial fibrillation (NVAF) during the administration of 110 mg of dabigatran twice a day after catheter ablation. METHODS: One hundred and seventy-two NVAF patients who were hospitalized and received catheter ablation in Jiangsu Provincial People's Hospital from January 2014 to January 2015 were enrolled (110 mg of dabigatran was administered orally to outpatients preoperatively twice a day for 3 weeks)...
November 2, 2016: Cardiology
https://www.readbyqxmd.com/read/27782345/safety-and-clinical-outcomes-of-catheter-ablation-of-atrial-fibrillation-in-patients-with-chronic-kidney-disease
#9
Aditya J Ullal, Daniel W Kaiser, Jun Fan, Susan Schmitt, Claire T Than, Wolfgang C Winkelmayer, Paul A Heidenreich, Jonathon P Piccini, Marco V Perez, Paul J Wang, Mintu P Turakhia
INTRODUCTION: Data regarding catheter ablation of atrial fibrillation (AF) in patients with chronic kidney disease (CKD) is limited. We therefore assessed the association of CKD with common safety and clinical outcomes in a nationwide sample of ablation recipients. METHODS: Using MarketScan(®) Commercial Claims and Medicare Supplemental Databases, we evaluated 30-day safety and 1-year clinical outcomes in patients who underwent a first AF ablation procedure between 2007-2011...
October 26, 2016: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/27775782/observation-of-the-efficacy-of-radiofrequency-catheter-ablation-on-patients-with-different-forms-of-atrial-fibrillation
#10
R-C Zhao, W Han, J Han, J Yu, J Guo, J-L Fu, Z Li, R-Z Zhao
OBJECTIVE: To study the efficacy and safety of radiofrequency catheter ablation (RFCA) in patients with different forms of atrial fibrillation. PATIENTS AND METHODS: By retrospective analysis, we summarize 720 cases, where patients diagnosed with atrial fibrillation in our hospital were treated with RFCA from February 2010 to October 2014. Among the cases, 425 were diagnosed with paroxysmal atrial fibrillation and 295 with non-paroxysmal atrial fibrillation (including persistent atrial fibrillation and permanent atrial fibrillation)...
October 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27754137/os-27-01-is-hypertension-a-risk-factor-for-recurrence-after-radiofrequency-catheter-ablation-in-atrial-fibrillation
#11
Mi-Na Kim, Donghyuk Cho, Jae-Min Shim, Jong Il Choi, Seong-Mi Park, Young-Hoon Kim, Wan-Joo Shim
OBJECTIVE: Hypertension (HT) is the important risk factor for atrial fibrillation (AF). Hemodynamic overload by increased blood pressure causes atrial wall stretch and atrial dysfunction. Left atrial (LA) dysfunction has been regarded as the most important risk factor for AF recurrence after radiofrequency catheter ablation (RFCA). But there are controversies regarding the role of hypertension as a risk factor of AF recurrence after RFCA. The aim of this study was to assess whether the hypertension is an independent risk factor for AF recurrence after RFCA...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27748530/sudden-death-and-its-risk-factors-after-atrioventricular-junction-ablation-and-pacemaker-implantation-in-patients-with-atrial-fibrillation
#12
Ru-Xing Wang, Hon-Chi Lee, Jia-Ping Li, David O Hodge, Yong-Mei Cha, Paul A Friedman, Thomas M Munger, Komandoor Srivathsan, Behzad B Pavri, Win-Kuang Shen
BACKGROUND: Although sudden death (SD) is a rare complication after atrioventricular junction (AVJ) ablation and permanent pacemaker implantation, the risk factors leading to this SD remain unknown. The purpose of this study was to investigate SD and its risk factors after ablate-and-pace strategy for rate control in atrial fibrillation (AF) patients during long-term follow-up. HYPOTHESIS: METHODS: From January 2005 to December 2009, we enrolled into this study 517 AF patients with AVJ ablation and right ventricular pacemaker implantation...
October 17, 2016: Clinical Cardiology
https://www.readbyqxmd.com/read/27734699/-thyroid-hormones-and-cardiovascular-system
#13
Zdeňka Límanová, Jan Jiskra
Cardiovascular system is essentially affected by thyroid hormones by way of their genomic and non-genomic effects. Untreated overt thyroid dysfunction is associated with higher cardiovascular risk. Although it has been studied more than 3 decades, in subclinical thyroid dysfunction the negative effect on cardiovascular system is much more controversial. Large meta-analyses within last 10 years have shown that subclinical hyperthyroidism is associated with higher cardiovascular risk than subclinical hypothyroidism...
2016: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27647995/impact-of-cryoballoon-ablation-in-hypertrophic-cardiomyopathy-related-heart-failure-due-to-paroxysmal-atrial-fibrillation-a-comparative-case-series
#14
Petra Maagh, Gunnar Plehn, Arnd Christoph, Ahmet Oernek, Axel Meissner
Background: Atrial fibrillation (AF) represents a turning point in hypertrophic cardiomyopathy (HCM). Pulmonary Vein Isolation (PVI) with Radiofrequency Catheter Ablation (RFCA) is accepted to be successful in restoring sinus rhythm (SR) in HCM patients. The efficacy of cryoballoon (CB) therapy in HCM patients has not been studied so far. Methods: 166 patients with AF underwent PVI with CB technology in our single center between 1/2012 and 12/2015. To evaluate the efficacy of the CB therapy in HCM patients, we compared their clinical outcome with those in "Non-HCM" AF patients in a 3 and 6 months follow-up...
2016: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/27643064/os-27-01-is-hypertension-a-risk-factor-for-recurrence-after-radiofrequency-catheter-ablation-in-atrial-fibrillation
#15
Mi-Na Kim, Donghyuk Cho, Jae-Min Shim, Jong Il Choi, Seong-Mi Park, Young-Hoon Kim, Wan-Joo Shim
OBJECTIVE: Hypertension (HT) is the important risk factor for atrial fibrillation (AF). Hemodynamic overload by increased blood pressure causes atrial wall stretch and atrial dysfunction. Left atrial (LA) dysfunction has been regarded as the most important risk factor for AF recurrence after radiofrequency catheter ablation (RFCA). But there are controversies regarding the role of hypertension as a risk factor of AF recurrence after RFCA. The aim of this study was to assess whether the hypertension is an independent risk factor for AF recurrence after RFCA...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27623680/exploring-unmet-needs-in-venous-and-arterial-thromboembolism-with-rivaroxaban
#16
Riccardo Cappato, Robert Welsh
The vast clinical research programme for the direct, oral factor Xa inhibitor rivaroxaban has generated a wealth of data since the first rivaroxaban approval in 2008 for the prevention of venous thromboembolism (VTE) in patients undergoing elective hip or knee replacement surgery. While rivaroxaban is widely used across a spectrum of seven indications, there is continuous commitment to investigating its wider benefits in new indications and attempts to refine current evidence. Key data from recently completed randomised controlled trials (RCTs) have shown that rivaroxaban is a feasible anticoagulation option for patients with non-valvular atrial fibrillation (NVAF) undergoing cardioversion or catheter ablation...
September 28, 2016: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/27619629/pursuing-early-catheter-ablation-to-treat-atrial-fibrillation-in-the-congestive-heart-failure-population-significance-of-the-aatac-trial-results
#17
EDITORIAL
Karen P Phillips
No abstract text is available yet for this article.
August 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27612549/anti-arrhythmic-strategies-for-atrial-fibrillation-the-role-of-computational-modeling-in-discovery-development-and-optimization
#18
REVIEW
Eleonora Grandi, Mary M Maleckar
Atrial fibrillation (AF), the most common cardiac arrhythmia, is associated with increased risk of cerebrovascular stroke, and with several other pathologies, including heart failure. Current therapies for AF are targeted at reducing risk of stroke (anticoagulation) and tachycardia-induced cardiomyopathy (rate or rhythm control). Rate control, typically achieved by atrioventricular nodal blocking drugs, is often insufficient to alleviate symptoms. Rhythm control approaches include antiarrhythmic drugs, electrical cardioversion, and ablation strategies...
December 2016: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27609551/late-atypical-atrial-flutter-after-ablation-of-atrial-fibrillation
#19
Raquel Ferreira, João Primo, Luís Adão, Anabela Gonzaga, Helena Gonçalves, Rui Santos, Paulo Fonseca, José Santos, Vasco Gama
Cardiac surgery for structural heart disease (often involving the left atrium) and radiofrequency catheter ablation of atrial fibrillation have led to an increased incidence of regular atrial tachycardias, often presenting as atypical flutters. This type of flutter is particularly common after pulmonary vein isolation, especially after extensive atrial ablation including linear lesions and/or defragmentation. The authors describe the case of a 51-year-old man, with no relevant medical history, referred for a cardiology consultation in 2009 for paroxysmal atrial fibrillation...
October 2016: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/27560278/rhythm-control-in-atrial-fibrillation
#20
REVIEW
Jonathan P Piccini, Laurent Fauchier
Many patients with atrial fibrillation have substantial symptoms despite ventricular rate control and require restoration of sinus rhythm to improve their quality of life. Acute restoration (ie, cardioversion) and maintenance of sinus rhythm in patients with atrial fibrillation are referred to as rhythm control. The decision to pursue rhythm control is based on symptoms, the type of atrial fibrillation (paroxysmal, persistent, or long-standing persistent), patient comorbidities, general health status, and anticoagulation status...
August 20, 2016: Lancet
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